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Results for alx4a+alx4b

Z-value: 0.73

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Transcription factors associated with alx4a+alx4b

Gene Symbol Gene ID Gene Info
ENSDARG00000074442 ALX homeobox 4b
ENSDARG00000088332 ALX homeobox 4a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
alx4adr10_dc_chr7_-_26653629_266536370.214.4e-01Click!

Activity profile of alx4a+alx4b motif

Sorted Z-values of alx4a+alx4b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of alx4a+alx4b

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr21_+_6289363 0.62 ENSDART00000138600
si:ch211-225g23.1
chr5_+_39885307 0.52 ENSDART00000051055
NADH dehydrogenase (ubiquinone) Fe-S protein 4, (NADH-coenzyme Q reductase)
chr5_-_21015548 0.51 ENSDART00000040184
teneurin transmembrane protein 1
chr3_+_50511676 0.51 ENSDART00000102202
phosphatidic acid phosphatase type 2D
chr8_+_44619220 0.50 ENSDART00000063392
LSM1, U6 small nuclear RNA associated
chr7_-_29906486 0.49 ENSDART00000046689
transmembrane p24 trafficking protein 3
chr5_-_3673698 0.47

chr4_-_1952201 0.46 ENSDART00000135749
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr2_-_17721575 0.45 ENSDART00000141188
ENSDART00000100201
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr17_+_43041951 0.44 ENSDART00000154863
iron-sulfur cluster assembly 2
chr2_+_25659945 0.44 ENSDART00000161386
fibronectin type III domain containing 3Ba
chr16_+_23516127 0.43 ENSDART00000004679
ictacalcin
chr18_+_8362131 0.43 ENSDART00000092053
choline kinase beta
chr8_+_29733109 0.43 ENSDART00000020621
mitogen-activated protein kinase 4
chr12_+_47134830 0.42 ENSDART00000169406
ENSDART00000158568
ENSDART00000160616
5-methyltetrahydrofolate-homocysteine methyltransferase
chr19_+_1743359 0.41 ENSDART00000166744
DENN/MADD domain containing 3a
chr4_-_1952230 0.41 ENSDART00000135749
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr25_+_4454862 0.40 ENSDART00000110598
zmp:0000001167
chr6_+_11014565 0.39 ENSDART00000132677
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr13_-_36672606 0.39 ENSDART00000179242
salvador family WW domain containing protein 1
chr18_+_39506453 0.38 ENSDART00000126978
acyl-CoA dehydrogenase, long chain
chr23_-_24556810 0.38 ENSDART00000109248
spen family transcriptional repressor
chr8_+_31426328 0.38 ENSDART00000135101
selenoprotein P, plasma, 1a
chr3_-_32686790 0.37 ENSDART00000075465
myosin light chain, phosphorylatable, fast skeletal muscle a
chr14_+_5078937 0.35 ENSDART00000031508
ladybird homeobox 2
chr10_-_34058331 0.35 ENSDART00000046599
zygote arrest 1-like
chr19_+_32570656 0.35 ENSDART00000005255
mitochondrial ribosomal protein L53
chr10_-_25246786 0.34 ENSDART00000036906
karyopherin alpha 7 (importin alpha 8)
chr9_+_28329384 0.34 ENSDART00000046880
pleckstrin homology domain containing, family M, member 3
KN149830v1_-_31870 0.34 ENSDART00000167653
zgc:194336
chr9_-_1701626 0.34 ENSDART00000163482
heterogeneous nuclear ribonucleoprotein A3
chr6_-_33893933 0.34 ENSDART00000129916
transmembrane protein 69
chr24_-_32259086 0.34 ENSDART00000048633
tRNA aspartic acid methyltransferase 1
chr8_+_17739521 0.33 ENSDART00000112356
si:ch211-150o23.3
chr13_-_9509729 0.33 ENSDART00000101949
sideroflexin 4
chr14_-_14353487 0.32 ENSDART00000172241
NAD(P) dependent steroid dehydrogenase-like
chr8_-_11286377 0.32 ENSDART00000008215
phosphatidylinositol-4-phosphate 5-kinase, type I, beta b
chr4_+_74845382 0.32 ENSDART00000159789
zgc:172128
chr21_+_21158761 0.32 ENSDART00000058311
RPTOR independent companion of MTOR, complex 2b
chr25_+_30699938 0.32 ENSDART00000036275
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr14_-_4038642 0.32 ENSDART00000077348
caspase 3, apoptosis-related cysteine peptidase b
chr20_-_29961621 0.31 ENSDART00000132278
ring finger protein 144ab
chr18_-_15582896 0.31 ENSDART00000172690
ENSDART00000159915
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr4_-_75732882 0.31

chr21_+_27477153 0.31 ENSDART00000065420
phosphofurin acidic cluster sorting protein 1a
chr13_-_36672285 0.31 ENSDART00000012357
salvador family WW domain containing protein 1
chr2_-_17721810 0.30 ENSDART00000100201
ENSDART00000141188
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr10_+_33449922 0.30 ENSDART00000115379
ENSDART00000163458
ENSDART00000078012
zgc:153345
chr1_-_54570813 0.30 ENSDART00000098615
nanos homolog 3
chr16_-_25452949 0.30 ENSDART00000167574
ribosome binding factor A
chr15_+_34734212 0.30 ENSDART00000099776
tetraspanin 13a
chr9_-_22318918 0.30 ENSDART00000124272
crystallin, gamma M2d17
chr21_-_2350090 0.30 ENSDART00000168946
si:ch211-241b2.4
chr11_+_17849608 0.30 ENSDART00000020283
RNA pseudouridylate synthase domain containing 4
chr20_-_29961589 0.29 ENSDART00000132278
ring finger protein 144ab
chr3_-_6633512 0.28 ENSDART00000165273
golgi associated, gamma adaptin ear containing, ARF binding protein 3
chr20_+_34693415 0.28 ENSDART00000138338
ENSDARG00000054723
chr17_-_52233071 0.28

chr3_-_15889742 0.28 ENSDART00000143324
splA/ryanodine receptor domain and SOCS box containing 3a
chr7_+_23752492 0.27 ENSDART00000141165
TERF1 (TRF1)-interacting nuclear factor 2
chr5_+_65633207 0.27 ENSDART00000114532
MALT paracaspase 1
chr11_+_44108192 0.26 ENSDART00000165219
ENSDART00000160678
serine/arginine-rich splicing factor 7b
chr18_-_188494 0.26 ENSDART00000166207
ENSDART00000172235
ENSDART00000170884
phosphoribosylglycinamide formyltransferase
chr21_+_25199691 0.26 ENSDART00000168140
ENSDART00000112783
transmembrane protein 45B
chr24_+_17115897 0.26 ENSDART00000129554
bmi1 polycomb ring finger oncogene 1a
chr23_+_26806694 0.26 ENSDART00000035080
zgc:158263
chr21_+_25740782 0.26 ENSDART00000021620
claudin d
chr24_-_8585312 0.26

chr5_+_25133592 0.26 ENSDART00000098467
abhydrolase domain containing 17B
chr10_+_9575 0.26

chr16_+_1227270 0.25

chr4_+_5246465 0.25 ENSDART00000137966
coiled-coil domain containing 167
chr10_-_25737632 0.25 ENSDART00000135058
superoxide dismutase 1, soluble
chr20_-_29961498 0.25 ENSDART00000132278
ring finger protein 144ab
chr24_-_2278409 0.25

chr5_+_51992974 0.25 ENSDART00000170341
amyloid beta (A4) precursor protein-binding, family A, member 1a
chr8_+_23716843 0.25 ENSDART00000136547
ribosomal protein L10a
chr23_-_19299279 0.25 ENSDART00000080099
O-acyl-ADP-ribose deacylase 1
chr2_+_47827350 0.24

chr10_-_43874646 0.24 ENSDART00000025366
centrin 3
chr3_+_40022244 0.24 ENSDART00000102526
growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)
chr23_-_36922175 0.24

chr7_+_21006803 0.24 ENSDART00000052942
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr18_+_1353738 0.24 ENSDART00000165301
RAB27A, member RAS oncogene family
chr2_+_21267793 0.24 ENSDART00000099913
phospholipase A2, group IVAa (cytosolic, calcium-dependent)
chr20_-_9107294 0.24 ENSDART00000140792
OMA1 zinc metallopeptidase
chr17_-_9794176 0.24

chr6_+_18941186 0.24 ENSDART00000044519
connexin 44.2
chr16_+_3090170 0.24 ENSDART00000110395
LIM domains containing 1a
chr15_+_9351511 0.23 ENSDART00000144381
sarcoglycan, gamma
chr3_+_28808901 0.23 ENSDART00000141904
ENSDART00000077221
lectin, galactoside-binding, soluble, 1 (galectin 1)-like 1
chr18_+_8943793 0.23 ENSDART00000144247
si:dkey-5i3.5
chr9_+_24255064 0.23 ENSDART00000101577
ENSDART00000159324
ENSDART00000023196
ENSDART00000079689
ENSDART00000172743
ENSDART00000171577
leucine rich repeat (in FLII) interacting protein 1a
chr8_+_28493742 0.23 ENSDART00000053782
scratch family zinc finger 2
chr3_+_39437497 0.23 ENSDART00000055170
ceroid-lipofuscinosis, neuronal 3
chr15_-_21003820 0.23 ENSDART00000152371
ubiquitin specific peptidase 2a
chr1_-_25272318 0.23 ENSDART00000134192
synaptopodin 2b
chr15_-_5827067 0.23 ENSDART00000102459
retinol binding protein 2a, cellular
chr13_+_33138144 0.22 ENSDART00000002095
transmembrane protein 39B
chr16_+_53602834 0.22 ENSDART00000074653
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1b (glutamate binding)
chr19_+_12995955 0.22 ENSDART00000132892
collagen triple helix repeat containing 1a
chr23_-_42775849 0.22 ENSDART00000149944
glutathione peroxidase 7
chr10_-_35293024 0.22 ENSDART00000145804
yippee-like 2a
chr2_-_49114158 0.22

chr20_+_47639141 0.22 ENSDART00000043938
translocation associated membrane protein 2
chr10_+_1653720 0.22 ENSDART00000018532
TP53 regulated inhibitor of apoptosis 1
chr7_+_25052687 0.22 ENSDART00000110347
cytochrome P450, family 26, subfamily b, polypeptide 1
chr19_+_44413865 0.22 ENSDART00000136147
ENSDART00000151004
naked cuticle homolog 3
chr11_+_5522377 0.21 ENSDART00000013203
CSE1 chromosome segregation 1-like (yeast)
chr1_+_9633924 0.21 ENSDART00000029774
transmembrane protein 55Bb
chr16_+_42567707 0.21 ENSDART00000166640
si:ch211-215k15.5
chr3_-_34006846 0.21 ENSDART00000136900
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr15_-_16241341 0.21 ENSDART00000156352
si:ch211-259g3.4
chr23_-_32043229 0.21 ENSDART00000134550
ORMDL sphingolipid biosynthesis regulator 2
chr18_+_21419735 0.21 ENSDART00000144523
N-terminal EF-hand calcium binding protein 2
chr15_-_3023693 0.21

chr20_-_27193158 0.20 ENSDART00000062096
si:dkeyp-55f12.3
chr9_-_30765708 0.20 ENSDART00000101085
MORC family CW-type zinc finger 3a
chr18_+_8362265 0.20 ENSDART00000092053
choline kinase beta
chr8_+_7740132 0.20 ENSDART00000171325
transcription factor binding to IGHM enhancer 3a
chr14_+_8634518 0.20 ENSDART00000159920
ribosomal protein S6 kinase a, like
chr16_-_28723722 0.20 ENSDART00000148456
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr16_-_43061368 0.20 ENSDART00000113714
metaxin 1a
chr8_+_19945528 0.20 ENSDART00000134124
zinc finger protein 692
KN150200v1_+_7856 0.20

chr1_+_51087450 0.20 ENSDART00000040397
peroxiredoxin 2
chr2_-_2218945 0.20 ENSDART00000156951
ENSDARG00000097328
chr5_+_31475897 0.20 ENSDART00000144510
zinc finger, matrin-type 5
chr16_-_28723759 0.19 ENSDART00000148456
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr14_+_51934755 0.19

chr3_+_479366 0.19

chr14_-_8634381 0.19 ENSDART00000129030
zgc:153681
chr7_+_23752651 0.19 ENSDART00000141165
TERF1 (TRF1)-interacting nuclear factor 2
chr23_-_23474703 0.19 ENSDART00000078936
hairy-related 9
chr1_-_9256864 0.19 ENSDART00000041849
transmembrane protein 8A
chr4_-_951970 0.19 ENSDART00000093289
XRCC6 binding protein 1
chr2_-_58111727 0.19 ENSDART00000004431
ENSDART00000166845
ENSDART00000163999
erythrocyte membrane protein band 4.1-like 3b
chr19_-_22895095 0.19

chr7_-_73866202 0.19

chr14_-_45883839 0.19

chr2_+_31974269 0.19 ENSDART00000012413
ANKH inorganic pyrophosphate transport regulator b
chr19_+_44185325 0.19 ENSDART00000063870
ribosomal protein L11
chr5_-_40894631 0.19 ENSDART00000121840
eukaryotic translation elongation factor 2, like 2
chr21_+_22598805 0.19 ENSDART00000142495
ENSDARG00000089088
chr14_-_50075366 0.19 ENSDART00000021260
septin 8b
chr2_+_57734025 0.19 ENSDART00000143453
pleckstrin homology domain containing, family J member 1
chr3_-_21149752 0.18 ENSDART00000003939
synaptogyrin 1a
chr6_-_7577736 0.18 ENSDART00000151545
solute carrier family 25, member 38b
chr15_+_35076414 0.18 ENSDART00000165210
zgc:66024
chr23_+_11412329 0.18 ENSDART00000135406
cell adhesion molecule L1-like a
chr23_+_36023748 0.18

chr14_-_30630835 0.18 ENSDART00000010512
zgc:92907
chr24_-_10935904 0.18 ENSDART00000003195
charged multivesicular body protein 4C
chr22_+_16509286 0.18 ENSDART00000083063
T-cell acute lymphocytic leukemia 1
chr19_-_18664670 0.18 ENSDART00000108627
sorting nexin 10a
chr18_+_14715573 0.18 ENSDART00000108469
spermatogenesis associated 2-like
chr16_+_34038263 0.18 ENSDART00000134946
zinc finger, DHHC-type containing 18a
chr21_+_28921734 0.18 ENSDART00000166575
protein phosphatase 3, catalytic subunit, alpha isozyme
chr9_-_43736549 0.18 ENSDART00000140526
zinc finger protein 385B
chr11_-_38856849 0.18 ENSDART00000113185
adaptor-related protein complex 5, beta 1 subunit
chr13_+_40347099 0.18

chr14_-_17257773 0.18 ENSDART00000082667
fibroblast growth factor receptor-like 1a
chr19_-_35739239 0.18

chr17_-_21398340 0.18 ENSDART00000007021
ATPase, H+ transporting, lysosomal, V1 subunit B, member a
chr2_+_11902170 0.18 ENSDART00000138562
growth regulation by estrogen in breast cancer-like
chr22_-_19986461 0.17 ENSDART00000093310
cugbp, Elav-like family member 5a
chr4_+_22759177 0.17 ENSDART00000146272
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr3_+_26158051 0.17 ENSDART00000163500
ras homolog family member T1a
chr22_+_11943032 0.17 ENSDART00000105788
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr11_+_35790782 0.17 ENSDART00000125221
ENSDARG00000087939
chr3_-_48458042 0.17 ENSDART00000156822
cell death-inducing p53 target 1
chr20_-_47994364 0.17 ENSDART00000166857
ENSDARG00000100162
chr20_+_19613133 0.17 ENSDART00000152548
ENSDART00000063696
all-trans retinoic acid-induced differentiation factor
chr9_+_36092350 0.17 ENSDART00000005086
ATPase, Na+/K+ transporting, alpha 1b polypeptide
chr25_+_4534280 0.17 ENSDART00000130299
DEAF1 transcription factor
chr21_-_13026077 0.17 ENSDART00000024616
family with sequence similarity 219, member Aa
chr20_+_1724609 0.17

chr9_+_20715436 0.17 ENSDART00000141775
tripartite motif containing 45
chr11_+_15935769 0.17 ENSDART00000158824
chitobiase, di-N-acetyl-
chr22_-_19986607 0.17 ENSDART00000093310
cugbp, Elav-like family member 5a
KN150037v1_+_2317 0.16

chr21_+_31113731 0.16 ENSDART00000065366
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr1_+_51706536 0.16

chr24_+_8702288 0.16 ENSDART00000114810
synaptonemal complex protein 2-like
chr5_-_31796734 0.16 ENSDART00000142095
F-box and WD repeat domain containing 2
chr15_-_5636737 0.16 ENSDART00000114410
WD repeat domain 62
chr2_+_51087570 0.16

chr13_-_24778226 0.16

chr19_+_5562107 0.16 ENSDART00000082080
junction plakoglobin b
chr12_-_7902815 0.16 ENSDART00000088100
ankyrin 3b
chr8_-_12253026 0.16 ENSDART00000091612
DAB2 interacting protein a
chr9_-_30553051 0.16 ENSDART00000147030
synaptotagmin-like 5
chr6_+_8362892 0.16 ENSDART00000032118
ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)
chr17_+_24300332 0.15 ENSDART00000064083
orthodenticle homeobox 1b
chr19_-_5186692 0.15 ENSDART00000037007
triosephosphate isomerase 1a
chr21_-_2273243 0.15 ENSDART00000168712
si:ch73-299h12.6
chr22_+_35229139 0.15 ENSDART00000061315
ENSDART00000146430
TSC22 domain family 2
chr19_-_22182031 0.15 ENSDART00000104279
zinc finger protein 516
chr19_-_2084281 0.15

chr6_+_18941289 0.15 ENSDART00000044519
connexin 44.2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:1901909 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.4 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.1 0.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.4 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.3 GO:0070658 mechanosensory epithelium regeneration(GO:0070655) mechanoreceptor differentiation involved in mechanosensory epithelium regeneration(GO:0070656) neuromast regeneration(GO:0070657) neuromast hair cell differentiation involved in neuromast regeneration(GO:0070658)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.2 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 0.2 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 0.4 GO:0046084 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.1 0.4 GO:1990748 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 0.2 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.1 0.2 GO:0090594 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698) inflammatory response to wounding(GO:0090594)
0.1 0.4 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.5 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.2 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.2 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.2 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.2 GO:0045669 regulation of osteoblast proliferation(GO:0033688) positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.3 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.0 0.3 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.6 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.2 GO:0007589 body fluid secretion(GO:0007589)
0.0 0.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.2 GO:0060148 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.2 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.0 0.1 GO:0090344 negative regulation of cell aging(GO:0090344)
0.0 0.4 GO:0006555 methionine metabolic process(GO:0006555) methionine biosynthetic process(GO:0009086)
0.0 0.3 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.2 GO:0001881 receptor recycling(GO:0001881)
0.0 0.2 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.1 GO:0090303 positive regulation of wound healing(GO:0090303)
0.0 0.3 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0042423 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0 0.3 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 0.4 GO:0016233 telomere capping(GO:0016233)
0.0 0.1 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.1 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.2 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.0 0.2 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.1 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:0007168 cGMP biosynthetic process(GO:0006182) receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.8 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.3 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.2 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.1 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.0 0.1 GO:1902868 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.0 0.2 GO:0051654 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) establishment of mitochondrion localization(GO:0051654)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.2 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.0 0.3 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.4 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.3 GO:0019827 stem cell population maintenance(GO:0019827)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.3 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.2 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.2 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 0.3 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.0 GO:0019478 D-amino acid catabolic process(GO:0019478) D-serine catabolic process(GO:0036088) D-amino acid metabolic process(GO:0046416) D-serine metabolic process(GO:0070178)
0.0 0.1 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.1 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.0 0.5 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.1 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.1 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249) positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.3 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.1 GO:1900153 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.4 GO:0070187 telosome(GO:0070187)
0.1 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0071914 prominosome(GO:0071914)
0.0 0.2 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:0043186 P granule(GO:0043186)
0.0 0.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.6 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.1 0.9 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.4 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.4 GO:0016936 galactoside binding(GO:0016936)
0.1 0.3 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 0.3 GO:0001729 ceramide kinase activity(GO:0001729)
0.1 0.3 GO:1903231 mRNA binding involved in posttranscriptional gene silencing(GO:1903231)
0.1 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.4 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) efflux transmembrane transporter activity(GO:0015562)
0.1 0.2 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.1 0.2 GO:0004568 chitinase activity(GO:0004568)
0.1 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.2 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 0.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0102345 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.3 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.1 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.0 0.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.0 0.2 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.3 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.3 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.5 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.4 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.0 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.2 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.0 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.3 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0035804 structural constituent of egg coat(GO:0035804)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.0 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.3 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.4 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type