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DANIO-CODE

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Results for ar_nr3c1

Z-value: 2.04

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Transcription factors associated with ar_nr3c1

Gene Symbol Gene ID Gene Info
ENSDARG00000067976 androgen receptor
ENSDARG00000025032 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr3c1dr10_dc_chr14_-_23503974_235041370.683.5e-03Click!

Activity profile of ar_nr3c1 motif

Sorted Z-values of ar_nr3c1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ar_nr3c1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_-_45258675 7.29 ENSDART00000158855
FXYD domain containing ion transport regulator 1 (phospholemman)
chr15_-_9055873 7.25 ENSDART00000124998
reticulon 2a
chr21_+_11410738 6.84 ENSDART00000146701
si:dkey-184p9.7
chr22_-_951880 6.76 ENSDART00000105895
ENSDART00000172206
calcium channel, voltage-dependent, L type, alpha 1S subunit, a
chr19_+_10936229 5.90 ENSDART00000172219
apolipoprotein Ea
KN149955v1_+_4206 5.83 ENSDART00000167370
cyclin-dependent kinase inhibitor 1D
chr13_+_39110160 5.59 ENSDART00000111458
zgc:172136
chr16_+_32605735 5.49 ENSDART00000093250
POU class 3 homeobox 2b
chr10_+_26705729 5.34 ENSDART00000147013
si:ch73-52f15.5
chr19_+_7798512 5.24 ENSDART00000104719
ENSDART00000146747
tuftelin 1b
chr5_-_43334777 5.16 ENSDART00000142271
ENSDARG00000053091
chr7_+_58397256 5.11 ENSDART00000049264
short chain dehydrogenase/reductase family 16C, member 5b
chr18_-_39491932 4.80 ENSDART00000122930
secretogranin III
chr15_-_23407388 4.52 ENSDART00000020425
melanoma cell adhesion molecule b
chr11_+_13470883 4.28 ENSDART00000011362
arrestin domain containing 2
chr4_+_4795126 4.21 ENSDART00000129252
solute carrier family 13 (sodium/sulfate symporter), member 4
chr13_+_28689749 4.21 ENSDART00000101653
ENSDARG00000062790
chr25_+_3232912 4.09 ENSDART00000104877
ENSDART00000170765
ENSDART00000158571
coiled-coil-helix-coiled-coil-helix domain containing 3b
chr16_+_10885785 3.98 ENSDART00000161969
ATPase, Na+/K+ transporting, alpha 3b polypeptide
chr11_-_25592102 3.89 ENSDART00000103549
v-ski avian sarcoma viral oncogene homolog b
chr18_-_48750637 3.77 ENSDART00000097259
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr18_-_25010085 3.66 ENSDART00000133786
si:ch211-196l7.4
chr9_+_49054601 3.59 ENSDART00000047401
ATP-binding cassette, sub-family B (MDR/TAP), member 11a
chr21_-_25528699 3.55 ENSDART00000144917
ENSDARG00000089836
chr5_+_31606213 3.53 ENSDART00000126873
myosin, heavy polypeptide 2, fast muscle specific
chr20_+_37940880 3.50 ENSDART00000165887
feline leukemia virus subgroup C cellular receptor 1
chr11_-_25592017 3.34 ENSDART00000103549
v-ski avian sarcoma viral oncogene homolog b
chr23_+_35609887 3.28 ENSDART00000179393
tubulin, alpha 1b
chr8_+_7340538 3.21 ENSDART00000121708
proprotein convertase subtilisin/kexin type 1 inhibitor, like
chr16_-_32605560 3.20

chr8_-_4903896 3.16 ENSDART00000004986
immunoglobulin superfamily, member 9b
chr4_+_4223606 3.10

chr1_+_23385409 2.98 ENSDART00000014608
mab-21-like 2
chr23_+_37355971 2.96

chr3_+_23563620 2.94 ENSDART00000147022
homeobox B7a
chr5_+_22752368 2.90 ENSDART00000142915
si:dkey-125i10.3
chr20_+_25441689 2.85 ENSDART00000063028
connective tissue growth factor a
chr4_-_12726432 2.84 ENSDART00000132286
microsomal glutathione S-transferase 1.2
chr20_-_6822668 2.82 ENSDART00000169569
insulin-like growth factor binding protein 1a
chr2_-_48341913 2.81 ENSDART00000139944
si:dkeyp-12a9.5
chr25_-_20994084 2.75 ENSDART00000154765
proline rich 5a (renal)
chr17_+_29328653 2.74 ENSDART00000086164
potassium channel tetramerization domain containing 3
chr12_-_46943791 2.74 ENSDART00000084557
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr24_+_35676505 2.70 ENSDART00000122734
CCAAT/enhancer binding protein (C/EBP), delta
chr3_-_54866453 2.69 ENSDART00000125092
hemoglobin, alpha embryonic 1
chr9_-_47042015 2.64 ENSDART00000054137
insulin-like growth factor binding protein 5b
chr18_+_26437604 2.62 ENSDART00000060245
cathepsin H
chr1_+_30941618 2.57 ENSDART00000044214
WW domain binding protein 1-like b
chr14_-_27703812 2.54 ENSDART00000054115
TSC22 domain family, member 3
chr21_-_19280266 2.53 ENSDART00000141596
glycerol-3-phosphate acyltransferase 3
chr23_+_45020761 2.51 ENSDART00000159104
ATPase, Na+/K+ transporting, beta 2a polypeptide
chr18_-_35755677 2.50 ENSDART00000036015
ryanodine receptor 1b (skeletal)
KN149955v1_+_4134 2.48 ENSDART00000167370
cyclin-dependent kinase inhibitor 1D
chr9_+_1225808 2.45 ENSDART00000177730
ENSDARG00000107255
chr18_-_48750433 2.44 ENSDART00000097259
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr23_-_39956151 2.43 ENSDART00000115330
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr21_+_28441951 2.32 ENSDART00000077887
solute carrier family 22 (organic anion transporter), member 6, like
chr19_+_17926983 2.31 ENSDART00000141397
ubiquitin-conjugating enzyme E2E 1
chr12_-_28456044 2.30 ENSDART00000008010
pyruvate dehydrogenase kinase, isozyme 2a
chr3_-_30948297 2.30 ENSDART00000145636
elongin B
chr15_-_29454583 2.28 ENSDART00000145976
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr9_-_30437160 2.28 ENSDART00000147241
ENSDARG00000092870
chr3_-_35671276 2.26 ENSDART00000150911
CASK interacting protein 1
chr16_+_330953 2.26 ENSDART00000102977
neurensin 1
chr18_+_17439409 2.23 ENSDART00000100223
zgc:91860
chr4_-_20435099 2.17 ENSDART00000055317
leucine rich repeat containing 17
chr20_+_34640435 2.14 ENSDART00000152073
ENSDARG00000054723
chr16_-_46463900 2.10 ENSDART00000157045
ENSDARG00000097192
chr19_-_41819752 2.08 ENSDART00000167772
split hand/foot malformation (ectrodactyly) type 1
chr24_+_7607915 2.04 ENSDART00000124409
caveolae associated protein 1b
chr23_-_20332076 2.03 ENSDART00000147326
laminin, beta 2 (laminin S)
chr3_-_58488929 2.03 ENSDART00000042386
un-named sa1261
chr16_-_46463845 2.03 ENSDART00000157045
ENSDARG00000097192
chr1_-_32934338 2.02

chr2_+_52639037 2.01 ENSDART00000006216
phospholipid phosphatase 2a
chr8_+_19642272 1.96 ENSDART00000138176
forkhead box D2
chr10_-_43466392 1.95 ENSDART00000062631
hyaluronan and proteoglycan link protein 1b
chr16_-_31835463 1.95 ENSDART00000148389
chromodomain helicase DNA binding protein 4b
chr9_+_38975508 1.94

chr22_-_13325409 1.93 ENSDART00000154095
si:ch211-227m13.1
chr18_+_27119086 1.92 ENSDART00000086094
pleckstrin homology domain containing, family A member 7a
chr12_-_4648262 1.90 ENSDART00000152771
si:ch211-255p10.3
chr2_+_13373937 1.89 ENSDART00000142649
protein kinase, AMP-activated, gamma 2 non-catalytic subunit b
chr17_+_6119323 1.87 ENSDART00000131075
dual specificity phosphatase 23b
chr5_-_40894631 1.85 ENSDART00000121840
eukaryotic translation elongation factor 2, like 2
chr10_-_43466478 1.85 ENSDART00000062631
hyaluronan and proteoglycan link protein 1b
chr16_-_17439735 1.85 ENSDART00000144392
zyxin
chr2_-_24113073 1.84 ENSDART00000148685
xin actin binding repeat containing 1
chr25_+_4918339 1.84 ENSDART00000153980
parvin, beta
chr7_-_7442720 1.83 ENSDART00000091105
microfibrillar-associated protein 3-like
chr5_-_31301280 1.80 ENSDART00000141446
coronin, actin binding protein, 1Cb
chr20_+_230394 1.79 ENSDART00000002661
laminin, alpha 4
chr17_+_52736192 1.78 ENSDART00000158273
ENSDART00000161414
Meis homeobox 2a
chr3_+_16115708 1.77 ENSDART00000122519
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr1_+_4557485 1.77 ENSDART00000052423
sprouty RTK signaling antagonist 2
chr19_+_31046291 1.74 ENSDART00000052124
family with sequence similarity 49, member A-like
chr19_+_19839981 1.73 ENSDART00000113580
ENSDARG00000074216
chr12_-_16331781 1.68 ENSDART00000152133
HECT domain containing 2
chr16_-_21238288 1.67 ENSDART00000139737
chromobox homolog 3b
chr6_-_49064365 1.67 ENSDART00000156124
si:ch211-105j21.9
chr20_+_2255204 1.66 ENSDART00000137579
si:ch73-18b11.2
chr1_-_53247258 1.66 ENSDART00000007732
calpain 9
chr6_+_8895437 1.64 ENSDART00000162588
regucalcin
chr3_-_32205873 1.62 ENSDART00000156918
si:dkey-16p21.8
chr23_-_29138952 1.61 ENSDART00000002812
castor zinc finger 1
chr5_-_28888704 1.55

chr13_+_22119569 1.54 ENSDART00000108472
synaptopodin 2-like a
chr17_-_37447917 1.54 ENSDART00000075975
cysteine-rich protein 1
chr13_-_1177857 1.54 ENSDART00000111052
oligodendrocyte transcription factor 3
chr1_-_44348236 1.53 ENSDART00000023336
ribosomal protein S6
chr4_-_16417703 1.51 ENSDART00000013085
decorin
chr14_+_20632593 1.51 ENSDART00000166366
ENSDART00000106198
zgc:66433
chr2_+_26273986 1.50 ENSDART00000137746
solute carrier family 7, member 14a
chr17_+_381715 1.50 ENSDART00000162898
si:rp71-62i8.1
chr18_+_16755239 1.50 ENSDART00000133490
lymphatic vessel endothelial hyaluronic receptor 1b
chr17_+_52024610 1.48

chr23_-_5751064 1.47 ENSDART00000067351
troponin T type 2a (cardiac)
chr23_-_28367816 1.46 ENSDART00000003548
zinc finger protein 385A
chr5_-_69628472 1.45

chr2_+_3701942 1.44 ENSDART00000132572
glutamic pyruvate transaminase (alanine aminotransferase) 2, like
chr16_-_12375204 1.44 ENSDART00000113345
leukocyte receptor cluster (LRC) member 8
chr10_-_36864268 1.43 ENSDART00000165853
dehydrogenase/reductase (SDR family) member 13a, tandem duplicate 1
chr18_+_45121016 1.43 ENSDART00000172328
glycosyltransferase-like 1b
chr15_+_161444 1.42 ENSDART00000008504
mediator complex subunit 17
chr9_-_32942783 1.42 ENSDART00000060006
oligodendrocyte lineage transcription factor 2
chr10_-_37131530 1.40 ENSDART00000132023
myosin XVIIIAa
chr25_-_18234069 1.39 ENSDART00000104496
dual specificity phosphatase 6
chr1_+_15827083 1.39

chr20_-_46458839 1.36 ENSDART00000153087
Bcl2 modifying factor 2
chr17_+_52736535 1.35 ENSDART00000158273
ENSDART00000161414
Meis homeobox 2a
chr4_-_2595775 1.35 ENSDART00000132581
ENSDART00000019508
cysteine and glycine-rich protein 2
chr11_-_53846 1.34

chr1_-_58242892 1.34

chr23_+_17939650 1.33 ENSDART00000162822
nascent polypeptide-associated complex alpha subunit
chr12_+_18643598 1.32

chr11_+_132668 1.31 ENSDART00000163978
ENSDART00000170778
dual specificity phosphatase 7
chr19_+_44185325 1.31 ENSDART00000063870
ribosomal protein L11
chr5_-_28888658 1.28

chr7_-_23601966 1.26 ENSDART00000101408
zgc:162171
chr8_+_999710 1.26 ENSDART00000081432
sepiapterin reductase b
chr24_-_20812255 1.25 ENSDART00000142080
karyopherin alpha 1 (importin alpha 5)
chr15_+_15479719 1.25 ENSDART00000127436
zgc:92630
chr20_-_34898276 1.23 ENSDART00000048375
ENSDART00000132426
stathmin-like 4
chr25_-_23949331 1.23 ENSDART00000047569
insulin-like growth factor 2b
chr18_+_29178482 1.23 ENSDART00000137587
ENSDART00000144423
PTPRF interacting protein, binding protein 2a (liprin beta 2)
chr23_+_4955111 1.20 ENSDART00000023537
troponin C type 1a (slow)
chr4_-_72067910 1.19 ENSDART00000170308
ENSDARG00000101193
chr17_-_45403518 1.19 ENSDART00000156002
transmembrane protein 206
chr5_+_50947650 1.18 ENSDART00000058403
creatine kinase, mitochondrial 2b (sarcomeric)
chr4_+_4795530 1.17 ENSDART00000129252
solute carrier family 13 (sodium/sulfate symporter), member 4
chr19_-_31785558 1.16 ENSDART00000046609
scinderin
chr14_+_29428950 1.16 ENSDART00000105898
ENSDARG00000071567
chr3_-_33290990 1.16 ENSDART00000075493
ENSDART00000132293
coiled-coil domain containing 103
chr19_+_5501487 1.16 ENSDART00000132874
eukaryotic translation initiation factor 1B
chr22_-_13325475 1.15 ENSDART00000154095
si:ch211-227m13.1
chr12_-_26291790 1.15 ENSDART00000152941
ubiquitin specific peptidase 54b
chr1_+_33510660 1.13 ENSDART00000147201
solute carrier family 5 (sodium/choline cotransporter), member 7a
chr1_-_54319671 1.12 ENSDART00000074058
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23a
chr12_-_43939028 1.11 ENSDART00000170723
zgc:112964
chr19_-_3547521 1.11 ENSDART00000168139
human immunodeficiency virus type I enhancer binding protein 1
chr17_-_52735615 1.09

chr4_+_27141061 1.08 ENSDART00000145083
bromodomain containing 1a
chr25_-_20993989 1.07

chr25_+_446920 1.07 ENSDART00000104717
ribosomal L24 domain containing 1
chr9_-_38232999 1.07 ENSDART00000133998
3-hydroxyacyl-CoA dehydratase 2
chr21_+_25017684 1.05 ENSDART00000065132
zgc:171740
chr3_-_54414513 1.04 ENSDART00000053106
sphingosine-1-phosphate receptor 2
chr13_-_219661 1.03 ENSDART00000133731
si:ch1073-291c23.2
chr4_-_16365281 1.02 ENSDART00000139919
lumican
chr4_-_73484546 1.01

chr4_+_19545842 1.01 ENSDART00000140028
leucine rich repeat containing 4.1
chr11_-_23333850 0.98

chr21_+_11046459 0.97 ENSDART00000169024
alanine--glyoxylate aminotransferase 2
chr20_+_46683031 0.96 ENSDART00000153231
Jun dimerization protein 2b
chr14_-_9216303 0.95 ENSDART00000054689
atonal bHLH transcription factor 8
chr24_-_32750010 0.94 ENSDART00000038364
carbonic anhydrase II
chr9_+_30774173 0.94 ENSDART00000160590
TBC1 domain family, member 4
chr9_-_43736549 0.94 ENSDART00000140526
zinc finger protein 385B
chr14_+_51692872 0.93 ENSDART00000163856
nitric oxide associated 1
chr2_-_3571821 0.92 ENSDART00000092741
synaptosomal-associated protein, 47
chr3_+_19863136 0.92 ENSDART00000078974
transmembrane and ubiquitin-like domain containing 2
chr24_-_21750082 0.91

chr14_-_12001505 0.91 ENSDART00000171136
myotilin
chr6_+_23462412 0.89 ENSDART00000166192
phosphoinositide-3-kinase, regulatory subunit 5
chr16_-_5936637 0.88 ENSDART00000085678
trafficking protein, kinesin binding 1
chr16_-_46653204 0.88 ENSDART00000158341
transmembrane protein 176l.3a
chr10_-_38372282 0.88 ENSDART00000149580
nuclear receptor interacting protein 1b
chr2_+_54911012 0.87 ENSDART00000027313
NADH dehydrogenase (ubiquinone) flavoprotein 2
chr19_-_9779467 0.87

chr15_-_33782909 0.87 ENSDART00000167705
StAR-related lipid transfer (START) domain containing 13b
chr4_-_19992951 0.84 ENSDART00000169248
dopamine receptor D4 related sequence
chr16_+_46463904 0.84

chr10_-_13220838 0.84 ENSDART00000160265
muscle, skeletal, receptor tyrosine kinase
chr24_+_21828704 0.84 ENSDART00000042495
spermidine/spermine N1-acetyltransferase 1b
chr1_-_58258428 0.83

chr14_-_2437593 0.83 ENSDART00000157677
si:ch73-233f7.6
chr11_-_9479592 0.83 ENSDART00000175829
ENSDARG00000086489
chr5_-_40894693 0.83 ENSDART00000051081
eukaryotic translation elongation factor 2, like 2
chr21_-_19789339 0.82

chr25_+_28329427 0.82 ENSDART00000160619
solute carrier family 41 (magnesium transporter), member 2a

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 5.9 GO:0050999 regulation of nitric-oxide synthase activity(GO:0050999) positive regulation of nitric-oxide synthase activity(GO:0051000) beta-amyloid clearance(GO:0097242) regulation of beta-amyloid clearance(GO:1900221)
1.4 5.6 GO:0035332 positive regulation of hippo signaling(GO:0035332)
1.2 3.5 GO:0097037 heme export(GO:0097037)
0.7 2.2 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.6 1.9 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.6 2.5 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.6 3.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.6 5.8 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.5 1.5 GO:0007263 atrial cardiac muscle tissue development(GO:0003228) nitric oxide mediated signal transduction(GO:0007263)
0.5 1.4 GO:0021742 abducens nucleus development(GO:0021742)
0.5 1.4 GO:1905178 regulation of cardiac muscle tissue regeneration(GO:1905178)
0.5 2.8 GO:0038203 TORC2 signaling(GO:0038203)
0.4 1.6 GO:0050848 L-ascorbic acid metabolic process(GO:0019852) water-soluble vitamin biosynthetic process(GO:0042364) regulation of calcium-mediated signaling(GO:0050848)
0.4 6.5 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.4 3.0 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.3 3.8 GO:0070831 basement membrane assembly(GO:0070831)
0.3 1.0 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.3 0.9 GO:0015670 carbon dioxide transport(GO:0015670)
0.3 2.1 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.3 6.3 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.3 0.8 GO:0030815 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclic nucleotide metabolic process(GO:0030800) negative regulation of cyclic nucleotide biosynthetic process(GO:0030803) negative regulation of nucleotide biosynthetic process(GO:0030809) negative regulation of cAMP metabolic process(GO:0030815) negative regulation of cAMP biosynthetic process(GO:0030818) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350) negative regulation of purine nucleotide biosynthetic process(GO:1900372)
0.3 1.0 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.3 1.8 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.3 4.5 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.2 4.7 GO:0014823 response to activity(GO:0014823)
0.2 0.7 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.2 2.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.2 1.1 GO:1900619 neuromuscular synaptic transmission(GO:0007274) acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.2 1.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.2 0.8 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.2 0.6 GO:0035676 anterior lateral line neuromast hair cell development(GO:0035676)
0.2 1.8 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.2 0.5 GO:0032877 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.2 7.4 GO:0007050 cell cycle arrest(GO:0007050)
0.2 1.5 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.2 0.8 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.2 5.5 GO:0001885 endothelial cell development(GO:0001885)
0.2 0.6 GO:0006788 heme oxidation(GO:0006788)
0.2 1.4 GO:0042574 retinal metabolic process(GO:0042574)
0.2 3.3 GO:0030199 collagen fibril organization(GO:0030199)
0.2 0.5 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.1 1.2 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 1.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.5 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 1.2 GO:0090660 cerebrospinal fluid circulation(GO:0090660)
0.1 1.3 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 6.8 GO:0070509 calcium ion import(GO:0070509)
0.1 3.5 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.1 0.4 GO:1990092 calcium-dependent self proteolysis(GO:1990092)
0.1 6.4 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.1 1.2 GO:0032946 positive regulation of mononuclear cell proliferation(GO:0032946) positive regulation of T cell proliferation(GO:0042102) positive regulation of lymphocyte proliferation(GO:0050671) positive regulation of leukocyte proliferation(GO:0070665)
0.1 0.3 GO:0035552 oxidative RNA demethylation(GO:0035513) oxidative single-stranded DNA demethylation(GO:0035552) regulation of multicellular organism growth(GO:0040014)
0.1 0.3 GO:0015822 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.1 2.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.3 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.1 0.3 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.1 0.6 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 1.1 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 0.7 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.1 1.8 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 0.7 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.1 1.0 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.1 0.4 GO:0003379 establishment of cell polarity involved in gastrulation cell migration(GO:0003379)
0.1 1.3 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 0.9 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 1.9 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 1.5 GO:0050654 chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.1 3.2 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 0.7 GO:0009437 carnitine metabolic process(GO:0009437)
0.1 5.4 GO:0006814 sodium ion transport(GO:0006814)
0.1 0.4 GO:0051601 exocyst localization(GO:0051601)
0.1 0.8 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.5 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 1.1 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.5 GO:0009303 rRNA transcription(GO:0009303)
0.1 2.1 GO:0045214 sarcomere organization(GO:0045214)
0.1 1.2 GO:0051014 actin filament severing(GO:0051014)
0.1 0.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 2.7 GO:0051260 protein homooligomerization(GO:0051260)
0.1 2.7 GO:0006414 translational elongation(GO:0006414)
0.1 0.9 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 1.7 GO:0007586 digestion(GO:0007586)
0.0 0.6 GO:0007634 optokinetic behavior(GO:0007634)
0.0 1.4 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 1.2 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.6 GO:0051180 vitamin transport(GO:0051180)
0.0 0.7 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 1.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 2.2 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.6 GO:1902667 regulation of axon guidance(GO:1902667)
0.0 0.9 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 3.8 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 1.0 GO:1902749 regulation of cell cycle G2/M phase transition(GO:1902749)
0.0 0.6 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.1 GO:0010456 cell proliferation in dorsal spinal cord(GO:0010456)
0.0 1.3 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.8 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 3.1 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 1.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 1.8 GO:0021782 glial cell development(GO:0021782)
0.0 1.0 GO:0071560 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 1.0 GO:0006865 amino acid transport(GO:0006865)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.3 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 1.1 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.4 GO:0003146 heart jogging(GO:0003146)
0.0 0.5 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.1 GO:0032526 response to retinoic acid(GO:0032526)
0.0 1.2 GO:0006413 translational initiation(GO:0006413)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 5.9 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.4 1.3 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.4 4.8 GO:0030667 secretory granule membrane(GO:0030667)
0.4 2.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.3 3.8 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.3 1.9 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.3 2.5 GO:1904949 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.3 1.2 GO:0005858 axonemal dynein complex(GO:0005858)
0.3 6.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.3 3.5 GO:0061617 MICOS complex(GO:0061617)
0.2 0.6 GO:1902560 GMP reductase complex(GO:1902560)
0.2 1.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 3.5 GO:0005861 troponin complex(GO:0005861)
0.2 2.8 GO:0031932 TORC2 complex(GO:0031932)
0.1 1.2 GO:0002102 podosome(GO:0002102)
0.1 5.1 GO:0005811 lipid particle(GO:0005811)
0.1 0.9 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.1 0.6 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 6.3 GO:0016459 myosin complex(GO:0016459)
0.1 1.4 GO:0070847 core mediator complex(GO:0070847)
0.1 1.8 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 2.9 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 5.6 GO:0016324 apical plasma membrane(GO:0016324)
0.1 4.7 GO:0030018 Z disc(GO:0030018)
0.1 1.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 3.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.2 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.2 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.0 1.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.5 GO:0043195 terminal bouton(GO:0043195)
0.0 0.4 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0005903 brush border(GO:0005903) brush border membrane(GO:0031526)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 3.2 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.9 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.3 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.3 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 3.8 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0034707 chloride channel complex(GO:0034707)
0.0 3.3 GO:0005874 microtubule(GO:0005874)
0.0 0.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.4 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.6 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.8 8.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.7 2.9 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.7 6.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.6 5.6 GO:0033613 activating transcription factor binding(GO:0033613)
0.6 5.8 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.5 2.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.4 2.5 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.4 2.5 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.4 4.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.4 1.1 GO:0102345 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.4 5.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 3.5 GO:0015232 heme transporter activity(GO:0015232)
0.3 2.3 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.2 2.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 2.2 GO:0048495 Roundabout binding(GO:0048495)
0.2 4.6 GO:0005518 collagen binding(GO:0005518)
0.2 8.0 GO:0008373 sialyltransferase activity(GO:0008373)
0.2 1.1 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.2 0.8 GO:0099528 G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.2 0.8 GO:0019809 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.2 0.6 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.2 2.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 1.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 1.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 4.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 0.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 1.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 0.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 2.5 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.2 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 1.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 7.2 GO:0046332 SMAD binding(GO:0046332)
0.1 0.4 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.7 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 2.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.3 GO:0035515 DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
0.1 0.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 1.7 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.3 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 0.5 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 0.7 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 1.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 1.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 3.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.9 GO:0016208 AMP binding(GO:0016208)
0.1 1.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 2.7 GO:0043022 ribosome binding(GO:0043022)
0.1 3.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.7 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 1.0 GO:0008483 transaminase activity(GO:0008483)
0.1 0.5 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.9 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 4.9 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 4.9 GO:0003774 motor activity(GO:0003774)
0.0 1.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.6 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 2.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 5.7 GO:0008514 organic anion transmembrane transporter activity(GO:0008514)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 2.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 2.5 GO:0042277 peptide binding(GO:0042277)
0.0 3.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 3.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0022884 protein transmembrane transporter activity(GO:0008320) macromolecule transmembrane transporter activity(GO:0022884)
0.0 0.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 3.4 GO:0051015 actin filament binding(GO:0051015)
0.0 2.8 GO:0003779 actin binding(GO:0003779)
0.0 1.2 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.2 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 2.7 GO:0015631 tubulin binding(GO:0015631)
0.0 1.0 GO:0003678 DNA helicase activity(GO:0003678)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 5.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 3.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 1.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 0.6 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 0.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 1.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.9 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.8 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.3 2.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 4.1 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.2 3.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.2 1.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 1.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 1.8 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.2 1.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 2.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 2.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 4.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 0.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 4.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 0.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 3.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.7 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.6 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation