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Results for arntl1a+arntl1b

Z-value: 1.84

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Transcription factors associated with arntl1a+arntl1b

Gene Symbol Gene ID Gene Info
arntl1a
ENSDARG00000006791 aryl hydrocarbon receptor nuclear translocator-like 1a
arntl1b
ENSDARG00000035732 aryl hydrocarbon receptor nuclear translocator-like 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
arntl1adr10_dc_chr25_-_17822194_17822207-0.783.2e-04Click!
arntl1bdr10_dc_chr7_+_65824459_658245250.263.4e-01Click!

Activity profile of arntl1a+arntl1b motif

Sorted Z-values of arntl1a+arntl1b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of arntl1a+arntl1b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_+_12733209 8.56 ENSDART00000167021
mcm6
minichromosome maintenance complex component 6
chr10_-_6816534 7.25 ENSDART00000110735
zgc:194281
zgc:194281
chr24_-_12794564 5.81 ENSDART00000024084
pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr10_-_44441481 5.67 ENSDART00000160231
sbno1
strawberry notch homolog 1 (Drosophila)
chr20_-_47521258 5.57

chr24_-_12794057 5.57 ENSDART00000024084
pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr21_-_4375313 4.86 ENSDART00000112460
dolk
dolichol kinase
chr24_-_33869817 4.75 ENSDART00000079283
tmeff1b
transmembrane protein with EGF-like and two follistatin-like domains 1b
chr7_+_55332040 4.57 ENSDART00000171736
trappc2l
trafficking protein particle complex 2-like
chr24_+_35676505 4.34 ENSDART00000122734
cebpd
CCAAT/enhancer binding protein (C/EBP), delta
chr7_+_6814828 4.01 ENSDART00000001649
actn3b
actinin alpha 3b
chr22_+_30234718 3.94 ENSDART00000172496
add3a
adducin 3 (gamma) a
chr16_-_9978112 3.92 ENSDART00000149312
ncalda
neurocalcin delta a
chr11_+_42265857 3.91 ENSDART00000039206
rps23
ribosomal protein S23
chr4_-_13922285 3.85 ENSDART00000080334
yaf2
YY1 associated factor 2
chr18_-_39491932 3.78 ENSDART00000122930
scg3
secretogranin III
chr14_+_25168063 3.64 ENSDART00000173436
si:dkey-280e21.3
si:dkey-280e21.3
chr16_-_24697750 3.61 ENSDART00000163305
fxyd6l
FXYD domain containing ion transport regulator 6 like
chr15_+_1187249 3.52 ENSDART00000152638
ENSDART00000152466
mlf1
myeloid leukemia factor 1
chr12_+_27032862 3.48

chr20_+_54512601 3.25 ENSDART00000169386
faua
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed a
chr24_-_12794672 3.23 ENSDART00000024084
pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr24_+_39213400 3.15 ENSDART00000115297
mss51
MSS51 mitochondrial translational activator
chr1_+_45063098 3.06 ENSDART00000084512
pkn1a
protein kinase N1a
chr8_+_19642272 2.92 ENSDART00000138176
foxd2
forkhead box D2
chr22_-_120677 2.89

chr16_+_24697776 2.80

chr25_+_222244 2.78 ENSDART00000155344
ENSDARG00000073905
ENSDARG00000073905
chr9_+_56881036 2.78

chr19_+_20177128 2.77 ENSDART00000168041
hoxa9a
homeobox A9a
chr19_+_7233537 2.77 ENSDART00000080348
brd2a
bromodomain containing 2a
chr6_+_45917081 2.76 ENSDART00000149450
ENSDART00000149642
h6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
KN150349v1_-_13313 2.76

chr13_-_23536022 2.76

chr11_+_7139675 2.74 ENSDART00000155864
CU929070.1
ENSDARG00000097452
chr7_-_29811734 2.69 ENSDART00000075600
tspan3b
tetraspanin 3b
chr9_-_24431684 2.67 ENSDART00000039399
cavin2a
caveolae associated protein 2a
chr20_-_25726868 2.66 ENSDART00000126716
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr6_-_37444877 2.62 ENSDART00000138351
cth
cystathionase (cystathionine gamma-lyase)
KN150670v1_-_72156 2.59

chr16_+_21109486 2.59 ENSDART00000079383
hoxa9b
homeobox A9b
chr16_+_6923898 2.54 ENSDART00000078306
arhgef2
rho/rac guanine nucleotide exchange factor (GEF) 2
chr22_-_23598571 2.54 ENSDART00000166800
cfhl4
complement factor H like 4
chr18_-_8697347 2.52 ENSDART00000093131
FRMD4A
FERM domain containing 4A
chr19_+_7234029 2.52 ENSDART00000080348
brd2a
bromodomain containing 2a
chr9_-_44493074 2.50 ENSDART00000167685
neurod1
neuronal differentiation 1
chr11_+_14142126 2.49 ENSDART00000102520
palm1a
paralemmin 1a
chr21_-_3548719 2.48 ENSDART00000137844
atp8b1
ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr1_-_18110990 2.44 ENSDART00000020970
pgm2
phosphoglucomutase 2
chr7_+_48727042 2.41 ENSDART00000166329
si:ch211-288d18.1
si:ch211-288d18.1
chr23_+_35996491 2.39 ENSDART00000127384
hoxc9a
homeobox C9a
chr4_+_828545 2.39 ENSDART00000067461
si:ch211-152c2.3
si:ch211-152c2.3
chr15_+_1238615 2.38 ENSDART00000167760
ENSDART00000163827
mfsd1
major facilitator superfamily domain containing 1
chr7_+_48726955 2.37 ENSDART00000166329
si:ch211-288d18.1
si:ch211-288d18.1
chr6_-_22504772 2.36 ENSDART00000170039
sept9b
septin 9b
chr19_+_34582100 2.36 ENSDART00000135592
poc1bl
POC1 centriolar protein homolog B (Chlamydomonas), like
chr6_-_36574848 2.32 ENSDART00000135413
her6
hairy-related 6
chr19_+_20183210 2.28 ENSDART00000164968
hoxa4a
homeobox A4a
KN149955v1_+_4134 2.28 ENSDART00000167370
cdkn1d
cyclin-dependent kinase inhibitor 1D
chr13_+_19753644 2.25 ENSDART00000089533
atrnl1a
attractin-like 1a
chr6_-_39608334 2.25 ENSDART00000179059
dip2bb
disco-interacting protein 2 homolog Bb
chr21_-_45341242 2.23 ENSDART00000075438
cdkn2aipnl
CDKN2A interacting protein N-terminal like
chr24_-_18775146 2.22 ENSDART00000144244
cpa6
carboxypeptidase A6
chr19_+_48499602 2.20

chr8_-_9081109 2.19 ENSDART00000176850
slc6a8
solute carrier family 6 (neurotransmitter transporter), member 8
chr4_+_317946 2.15 ENSDART00000132625
tulp4a
tubby like protein 4a
chr12_-_9479063 2.15 ENSDART00000169727
si:ch211-207i20.3
si:ch211-207i20.3
chr14_+_28136958 2.14

chr23_+_31986806 2.13 ENSDART00000136910
armc1l
armadillo repeat containing 1, like
chr25_+_36872560 2.12 ENSDART00000163178
slc10a3
solute carrier family 10, member 3
chr8_+_46378250 2.10 ENSDART00000129661
ENSDART00000084081
ogg1
8-oxoguanine DNA glycosylase
chr23_-_5785468 2.09 ENSDART00000033093
lad1
ladinin
chr25_+_36878565 2.08 ENSDART00000157596
ric3b
RIC3 acetylcholine receptor chaperone b
chr14_+_11089382 2.08 ENSDART00000106657
glod5
glyoxalase domain containing 5
chr19_+_20199890 2.04 ENSDART00000161019
hoxa4a
homeobox A4a
chr7_+_69119748 2.02 ENSDART00000177049
ENSDARG00000106989
ENSDARG00000106989
KN149955v1_+_4206 2.01 ENSDART00000167370
cdkn1d
cyclin-dependent kinase inhibitor 1D
chr5_-_9497591 2.01 ENSDART00000113448
ENSDARG00000073808
ENSDARG00000073808
chr3_+_23638277 2.01 ENSDART00000110682
hoxb1a
homeobox B1a
chr10_-_44180588 2.00 ENSDART00000145404
crybb1
crystallin, beta B1
chr19_-_27239468 1.99 ENSDART00000149132
neu1
neuraminidase 1
chr17_+_11264847 1.96 ENSDART00000153602
CU076099.1
ENSDARG00000097666
chr2_-_24661477 1.95 ENSDART00000078975
ENSDART00000155677
trnau1apb
tRNA selenocysteine 1 associated protein 1b
chr4_-_2187291 1.94 ENSDART00000150490
ENSDARG00000009262
ENSDARG00000009262
chr24_+_42133471 1.92 ENSDART00000170514
top1mt
topoisomerase (DNA) I, mitochondrial
chr10_-_22834248 1.91 ENSDART00000079469
pcolcea
procollagen C-endopeptidase enhancer a
chr24_-_14567403 1.89 ENSDART00000131830
jph1a
junctophilin 1a
chr6_-_32106882 1.89 ENSDART00000144772
BX664614.1
ENSDARG00000095311
chr10_-_11806373 1.88 ENSDART00000009715
adamts6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr21_-_20728623 1.88 ENSDART00000135940
ENSDART00000002231
ghrb
growth hormone receptor b
chr18_+_44656323 1.87 ENSDART00000059063
ehd2b
EH-domain containing 2b
chr20_+_32503118 1.83 ENSDART00000018640
snx3
sorting nexin 3
chr17_-_20267580 1.82 ENSDART00000078703
add3b
adducin 3 (gamma) b
chr25_+_31769985 1.82

chr21_-_15578808 1.81 ENSDART00000136666
mmp11b
matrix metallopeptidase 11b
chr7_-_13118705 1.81 ENSDART00000081212
polr2l
polymerase (RNA) II (DNA directed) polypeptide L
chr6_-_37444807 1.80 ENSDART00000138351
cth
cystathionase (cystathionine gamma-lyase)
chr8_+_46378706 1.79 ENSDART00000129661
ENSDART00000084081
ogg1
8-oxoguanine DNA glycosylase
chr5_+_26804344 1.78 ENSDART00000121886
ENSDART00000005025
hdr
hematopoietic death receptor
chr24_-_986371 1.77 ENSDART00000168961
ENSDART00000063151
napga
N-ethylmaleimide-sensitive factor attachment protein, gamma a
chr16_+_22950567 1.76 ENSDART00000143957
flad1
flavin adenine dinucleotide synthetase 1
chr12_-_26495741 1.73 ENSDART00000153168
slc16a5a
solute carrier family 16 (monocarboxylate transporter), member 5a
chr18_-_17527321 1.72

chr1_+_55077656 1.71 ENSDART00000144983
tecrb
trans-2,3-enoyl-CoA reductase b
chr7_-_40713381 1.70 ENSDART00000031700
en2a
engrailed homeobox 2a
chr23_+_5632124 1.70 ENSDART00000059307
smpd2a
sphingomyelin phosphodiesterase 2a, neutral membrane (neutral sphingomyelinase)
chr18_-_19114558 1.68 ENSDART00000177621
dennd4a
DENN/MADD domain containing 4A
chr24_-_42120772 1.67 ENSDART00000166413
ENSDART00000166414
ssr1
signal sequence receptor, alpha
chr22_-_24341408 1.67

chr23_+_39713307 1.67 ENSDART00000109464
g0s2
G0/G1 switch 2
chr19_-_791149 1.65 ENSDART00000151782
ENSDART00000037515
msto1
misato 1, mitochondrial distribution and morphology regulator
KN150487v1_+_15409 1.64 ENSDART00000166996
CABZ01074304.1
ENSDARG00000100224
chr9_-_24602136 1.63 ENSDART00000135897
tmeff2a
transmembrane protein with EGF-like and two follistatin-like domains 2a
chr20_+_46309812 1.63 ENSDART00000100532
stx7l
syntaxin 7-like
chr13_-_31310439 1.59 ENSDART00000076571
rtn1a
reticulon 1a
chr22_-_120910 1.56

chr17_+_37268262 1.54 ENSDART00000104009
slc30a1b
solute carrier family 30 (zinc transporter), member 1b
chr19_-_32931355 1.54 ENSDART00000103410
zbtb8b
zinc finger and BTB domain containing 8B
chr5_-_70939686 1.52

chr12_+_13614102 1.51 ENSDART00000152689
oplah
5-oxoprolinase (ATP-hydrolysing)
chr13_+_28382422 1.50 ENSDART00000043117
fbxw4
F-box and WD repeat domain containing 4
chr19_+_20177319 1.49 ENSDART00000170697
CR382300.2
ENSDARG00000100358
chr19_-_27152063 1.47 ENSDART00000109258
csnk2b
casein kinase 2, beta polypeptide
chr3_-_18605846 1.46 ENSDART00000145277
zgc:113333
zgc:113333
chr22_-_29133832 1.46 ENSDART00000172576
cbx6a
chromobox homolog 6a
chr2_+_2295529 1.44 ENSDART00000127286
si:ch73-140j24.4
si:ch73-140j24.4
chr13_+_29379602 1.43 ENSDART00000154120
chst3a
carbohydrate (chondroitin 6) sulfotransferase 3a
chr5_-_47523737 1.43 ENSDART00000153239
BX465834.1
ENSDARG00000095715
chr2_-_10602948 1.43 ENSDART00000016369
wls
wntless Wnt ligand secretion mediator
chr4_+_17364740 1.41 ENSDART00000136299
nup37
nucleoporin 37
chr14_+_151136 1.41 ENSDART00000165766
mcm7
minichromosome maintenance complex component 7
chr10_-_14530112 1.41 ENSDART00000176126
galt
galactose-1-phosphate uridylyltransferase
chr9_-_1964814 1.40 ENSDART00000082354
hoxd9a
homeobox D9a
chr19_+_20177234 1.39 ENSDART00000170697
CR382300.2
ENSDARG00000100358
chr2_+_54218444 1.38 ENSDART00000161221
capsla
calcyphosine-like a
chr13_+_16130212 1.36 ENSDART00000125813
mocos
molybdenum cofactor sulfurase
chr9_-_16845777 1.32 ENSDART00000160273
ENSDARG00000102261
ENSDARG00000102261
chr3_-_39485490 1.30 ENSDART00000123292
si:dkey-27o4.1
si:dkey-27o4.1
chr12_-_44825493 1.28 ENSDART00000016635
bccip
BRCA2 and CDKN1A interacting protein
chr8_+_41525623 1.28 ENSDART00000142377
ENSDARG00000078536
ENSDARG00000078536
chr20_-_2936289 1.26 ENSDART00000104667
cdk19
cyclin-dependent kinase 19
chr21_-_91068 1.26

chr9_+_33979089 1.25 ENSDART00000144623
kdm6a
lysine (K)-specific demethylase 6A
chr18_-_3741790 1.25

chr24_+_42133272 1.24 ENSDART00000170514
top1mt
topoisomerase (DNA) I, mitochondrial
chr24_-_36428001 1.23 ENSDART00000048046
naglu
N-acetylglucosaminidase, alpha
chr17_+_1950129 1.21 ENSDART00000110529
bub1bb
BUB1 mitotic checkpoint serine/threonine kinase Bb
chr20_-_13244278 1.19 ENSDART00000124470
ints7
integrator complex subunit 7
chr19_+_20164275 1.17 ENSDART00000160283
hoxa11a
homeobox A11a
chr19_+_20616655 1.16 ENSDART00000163026
igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr13_+_25069579 1.15 ENSDART00000039640
ap3m1
adaptor-related protein complex 3, mu 1 subunit
chr23_-_36319185 1.14 ENSDART00000139328
znf740b
zinc finger protein 740b
chr7_+_49381856 1.14 ENSDART00000141934
rassf7b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr24_-_33869772 1.14 ENSDART00000079283
tmeff1b
transmembrane protein with EGF-like and two follistatin-like domains 1b
chr8_-_46378116 1.13 ENSDART00000136602
qars
glutaminyl-tRNA synthetase
chr25_+_34244186 1.12 ENSDART00000087364
wwp2
WW domain containing E3 ubiquitin protein ligase 2
chr22_-_11106940 1.12 ENSDART00000016873
atp6ap2
ATPase, H+ transporting, lysosomal accessory protein 2
chr19_+_20177087 1.11 ENSDART00000168041
hoxa9a
homeobox A9a
chr18_+_44656426 1.11 ENSDART00000059063
ehd2b
EH-domain containing 2b
chr6_+_3655397 1.10 ENSDART00000178545
erich2
glutamate-rich 2
chr1_-_54319671 1.10 ENSDART00000074058
slc25a23a
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23a
chr15_+_8359658 1.10 ENSDART00000152603
egln2
egl-9 family hypoxia-inducible factor 2
chr23_+_758658 1.09

chr17_+_10345498 1.08 ENSDART00000081659
ENSDART00000169120
ENSDART00000170970
ENSDART00000140391
tyro3
TYRO3 protein tyrosine kinase
chr21_-_15578885 1.08 ENSDART00000136666
mmp11b
matrix metallopeptidase 11b
chr3_+_23621843 1.08 ENSDART00000146636
hoxb2a
homeobox B2a
chr23_+_35996779 1.08 ENSDART00000127384
hoxc9a
homeobox C9a
chr23_-_45356039 1.07 ENSDART00000067630
ENSDARG00000039901
ENSDARG00000039901
chr5_-_6004819 1.05 ENSDART00000099570
tnks1bp1
tankyrase 1 binding protein 1
chr20_+_40869520 1.04 ENSDART00000144401
tbc1d32
TBC1 domain family, member 32
chr13_-_25068717 1.04 ENSDART00000057605
adka
adenosine kinase a
chr2_-_23431625 1.04 ENSDART00000157318
BX548024.1
ENSDARG00000097593
chr15_-_37949371 1.04 ENSDART00000031418
hsc70
heat shock cognate 70
chr10_+_23052796 1.03 ENSDART00000138955
si:dkey-175g6.2
si:dkey-175g6.2
chr2_+_57825758 1.01

chr16_-_12345194 1.01 ENSDART00000114759
lpcat3
lysophosphatidylcholine acyltransferase 3
chr12_+_272930 1.00 ENSDART00000152639
ict1
immature colon carcinoma transcript 1
chr3_-_25290558 1.00 ENSDART00000154200
bptf
bromodomain PHD finger transcription factor
chr3_+_15667773 1.00 ENSDART00000055787
natd1
zgc:110779
chr8_+_17132156 0.99 ENSDART00000134665
cenph
centromere protein H
KN150699v1_+_15656 0.99 ENSDART00000167656
creg1
cellular repressor of E1A-stimulated genes 1
chr5_+_25604463 0.98 ENSDART00000137178
marveld2b
MARVEL domain containing 2b
chr22_+_38206685 0.97 ENSDART00000104527
tm4sf18
transmembrane 4 L six family member 18
chr3_+_22724101 0.97 ENSDART00000167127
BX322574.1
ENSDARG00000098353
chr22_-_13613870 0.97

chr2_+_50892294 0.96 ENSDART00000018150
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr20_+_33272248 0.94 ENSDART00000023963
ddx1
DEAD (Asp-Glu-Ala-Asp) box helicase 1
chr24_-_16772446 0.93 ENSDART00000110715
cmbl
carboxymethylenebutenolidase homolog (Pseudomonas)
chr1_+_17002495 0.92 ENSDART00000103236
ankrd37
ankyrin repeat domain 37
chr5_+_60871396 0.92 ENSDART00000131937
orai2
ORAI calcium release-activated calcium modulator 2
chr7_+_16854284 0.92 ENSDART00000013409
prmt3
protein arginine methyltransferase 3
chr16_-_204751 0.91

chr5_-_54773058 0.91 ENSDART00000145791
prune2
prune homolog 2 (Drosophila)
chr25_+_10450395 0.91 ENSDART00000067678
zgc:110339
zgc:110339
chr17_-_45750693 0.90 ENSDART00000074873
arf6b
ADP-ribosylation factor 6b
chr21_+_6858073 0.90 ENSDART00000139493
olfm1b
olfactomedin 1b
chr22_+_120930 0.90 ENSDART00000114777
nckipsd
NCK interacting protein with SH3 domain
chr23_+_44828346 0.90 ENSDART00000140799
zgc:85858
zgc:85858
chr25_-_35094733 0.90 ENSDART00000153827
clpxb
caseinolytic mitochondrial matrix peptidase chaperone subunit b
chr1_+_55077417 0.89 ENSDART00000144983
tecrb
trans-2,3-enoyl-CoA reductase b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 14.6 GO:0019543 propionate metabolic process(GO:0019541) propionate catabolic process(GO:0019543) glycerol biosynthetic process from pyruvate(GO:0046327) cellular response to dexamethasone stimulus(GO:0071549)
1.1 11.3 GO:0009954 proximal/distal pattern formation(GO:0009954)
1.1 4.4 GO:0019346 homoserine metabolic process(GO:0009092) cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) transsulfuration(GO:0019346)
0.8 10.0 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.7 2.0 GO:0010312 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.6 1.7 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.4 1.8 GO:0046443 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.4 1.7 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.4 2.0 GO:0021561 facial nerve development(GO:0021561)
0.4 3.9 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.4 1.4 GO:0061355 Wnt protein secretion(GO:0061355)
0.4 2.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.4 1.4 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.3 1.9 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.3 2.8 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.3 1.9 GO:0060416 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.3 5.3 GO:0002574 thrombocyte differentiation(GO:0002574)
0.3 1.0 GO:0044209 AMP salvage(GO:0044209)
0.3 1.0 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.2 1.2 GO:0045144 meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177) meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.2 2.9 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.2 3.2 GO:0006265 DNA topological change(GO:0006265)
0.2 5.8 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.2 1.2 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.2 2.5 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.2 3.6 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.2 1.7 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.2 1.6 GO:0048311 mitochondrion distribution(GO:0048311)
0.2 2.3 GO:0021794 thalamus development(GO:0021794)
0.2 2.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.2 2.9 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.2 1.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 0.9 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 1.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 1.6 GO:0070831 basement membrane assembly(GO:0070831)
0.1 0.8 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 1.8 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 2.3 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 0.6 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 1.8 GO:0098781 ncRNA transcription(GO:0098781)
0.1 1.0 GO:0042026 protein refolding(GO:0042026)
0.1 1.1 GO:0060021 palate development(GO:0060021)
0.1 1.1 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1 0.3 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 3.6 GO:0007050 cell cycle arrest(GO:0007050)
0.1 0.7 GO:0048899 anterior lateral line development(GO:0048899)
0.1 1.3 GO:0034453 microtubule anchoring(GO:0034453)
0.1 1.7 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 0.9 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 0.3 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 0.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 2.0 GO:0032456 endocytic recycling(GO:0032456)
0.0 2.5 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.6 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 1.0 GO:2000117 negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0 0.5 GO:0008272 sulfate transport(GO:0008272)
0.0 2.2 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 3.7 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 5.3 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 1.1 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.5 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 1.4 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.5 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.2 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.7 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 0.6 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 2.0 GO:0007601 visual perception(GO:0007601)
0.0 3.3 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 1.6 GO:0048278 vesicle docking(GO:0048278)
0.0 2.5 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.4 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 1.1 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.2 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.5 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 1.7 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 1.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 6.0 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 0.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 3.9 GO:0030900 forebrain development(GO:0030900)
0.0 3.2 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 1.9 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.5 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.1 GO:0072089 stem cell proliferation(GO:0072089)
0.0 0.1 GO:0060036 notochord cell vacuolation(GO:0060036)
0.0 5.9 GO:0006412 translation(GO:0006412)
0.0 0.8 GO:0006006 glucose metabolic process(GO:0006006)
0.0 0.1 GO:0046113 nucleobase catabolic process(GO:0046113)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0030314 junctional membrane complex(GO:0030314)
0.6 1.9 GO:0070195 growth hormone receptor complex(GO:0070195)
0.5 10.0 GO:0042555 MCM complex(GO:0042555)
0.4 1.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.3 3.8 GO:0030667 secretory granule membrane(GO:0030667)
0.3 4.6 GO:0030008 TRAPP complex(GO:0030008)
0.2 0.7 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
0.2 1.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.2 7.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 0.7 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.2 1.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 1.6 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 1.8 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 4.4 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 2.5 GO:0032587 ruffle membrane(GO:0032587)
0.1 1.8 GO:0005736 DNA-directed RNA polymerase II, core complex(GO:0005665) DNA-directed RNA polymerase I complex(GO:0005736)
0.1 2.4 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 6.1 GO:0060076 excitatory synapse(GO:0060076)
0.1 0.6 GO:0072379 ER membrane insertion complex(GO:0072379)
0.1 0.3 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 1.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 1.2 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 0.4 GO:1990246 uniplex complex(GO:1990246)
0.1 3.0 GO:0030139 endocytic vesicle(GO:0030139)
0.1 2.3 GO:0005604 basement membrane(GO:0005604)
0.1 0.5 GO:0032039 integrator complex(GO:0032039)
0.1 1.3 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 3.4 GO:0031201 SNARE complex(GO:0031201)
0.0 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 1.2 GO:0030686 90S preribosome(GO:0030686)
0.0 4.8 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.9 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 2.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 10.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.7 GO:0005814 centriole(GO:0005814)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 14.6 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
2.5 10.0 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
1.0 3.9 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.9 2.8 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.7 2.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.7 2.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.6 3.2 GO:0033149 FFAT motif binding(GO:0033149)
0.6 1.9 GO:0004903 growth hormone receptor activity(GO:0004903)
0.6 4.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.5 2.0 GO:0030151 molybdenum ion binding(GO:0030151)
0.5 2.3 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.4 1.8 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.4 4.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.4 1.4 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.3 1.0 GO:0004001 adenosine kinase activity(GO:0004001)
0.3 1.7 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.3 1.0 GO:0043515 kinetochore binding(GO:0043515)
0.3 3.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.3 1.8 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.3 1.0 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2 2.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 2.7 GO:0005080 protein kinase C binding(GO:0005080)
0.2 3.5 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.2 2.1 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.2 1.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 0.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 0.9 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 1.4 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 0.8 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 2.4 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 3.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 1.5 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 1.1 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.3 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.1 1.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.5 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 0.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 2.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.4 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.0 0.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.5 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.5 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 3.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.8 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 1.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 2.2 GO:0015293 symporter activity(GO:0015293)
0.0 5.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 3.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 29.6 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 5.8 GO:0051015 actin filament binding(GO:0051015)
0.0 12.2 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0048038 quinone binding(GO:0048038)
0.0 1.1 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 3.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 4.4 GO:0003924 GTPase activity(GO:0003924)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.8 GO:0003724 RNA helicase activity(GO:0003724)
0.0 1.6 GO:0005198 structural molecule activity(GO:0005198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.2 14.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.2 4.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 2.5 PID REELIN PATHWAY Reelin signaling pathway
0.1 3.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.4 PID ATR PATHWAY ATR signaling pathway
0.0 1.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 14.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.6 9.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.5 3.9 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.3 2.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.3 4.9 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.3 1.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 2.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.0 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 2.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.8 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 2.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 3.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 2.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 3.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 2.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 5.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 3.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 1.7 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 1.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 1.1 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.0 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 3.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.4 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 0.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.9 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane