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Results for arxb_drgx

Z-value: 1.26

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Transcription factors associated with arxb_drgx

Gene Symbol Gene ID Gene Info
ENSDARG00000101523 aristaless related homeobox b
ENSDARG00000069329 dorsal root ganglia homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
drgxdr10_dc_chr13_+_30781652_307816570.683.6e-03Click!
arxbdr10_dc_chr21_-_40653250_406532540.591.6e-02Click!

Activity profile of arxb_drgx motif

Sorted Z-values of arxb_drgx motif

Network of associatons between targets according to the STRING database.

First level regulatory network of arxb_drgx

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr25_+_18866796 5.83 ENSDART00000017299
thymine DNA glycosylase, tandem duplicate 1
chr7_+_21593005 4.43 ENSDART00000159626
si:dkey-85k7.7
chr1_+_44205158 4.04 ENSDART00000142820
wu:fc21g02
chr6_+_16341787 3.80 ENSDART00000114667
zgc:161969
chr22_-_32553488 3.08 ENSDART00000104693
poly(rC) binding protein 4
chr16_-_31763183 2.75 ENSDART00000169109
retinol binding protein 1a, cellular
chr7_+_26357875 2.72 ENSDART00000101044
heat shock factor binding protein 1a
chr4_+_9668755 2.64 ENSDART00000004604
si:dkey-153k10.9
chr14_-_20760787 2.51

chr6_+_23787804 2.43 ENSDART00000163188
zinc finger protein 648
chr6_-_15444945 2.31

chr20_-_21031504 2.27 ENSDART00000152726
BTB (POZ) domain containing 6b
chr16_+_24069711 2.11 ENSDART00000142869
apolipoprotein C-II
chr21_+_7844259 1.98 ENSDART00000027268
orthopedia homeobox a
chr2_+_30932612 1.90 ENSDART00000132450
ENSDART00000137012
myomesin 1a (skelemin)
chr4_+_5826813 1.72 ENSDART00000055414
peroxisomal biogenesis factor 26
chr6_+_16342020 1.72 ENSDART00000114667
zgc:161969
chr7_-_30096283 1.63 ENSDART00000075519
aldehyde dehydrogenase 1 family, member A2
chr1_-_40208544 1.62 ENSDART00000027463
H6 family homeobox 4
chr7_-_27877036 1.60 ENSDART00000044208
LIM domain only 1
chr17_-_19325678 1.59 ENSDART00000082085
goosecoid
chr5_-_30324182 1.56 ENSDART00000153909
spinster homolog 2 (Drosophila)
chr12_+_14702847 1.54

chr16_-_21334269 1.51 ENSDART00000145837
si:dkey-271j15.3
chr1_+_13779755 1.48

chr21_-_27845076 1.43 ENSDART00000132583
neurexin 2a
chr10_-_26782374 1.39 ENSDART00000162710
fibroblast growth factor 13b
chr2_-_48103519 1.39 ENSDART00000056305
frizzled class receptor 8b
chr17_-_8111181 1.36 ENSDART00000149873
ENSDART00000148403
Abelson helper integration site 1
chr22_-_15567180 1.34 ENSDART00000123125
tropomyosin 4a
chr23_-_18203680 1.34 ENSDART00000016976
nuclear casein kinase and cyclin-dependent kinase substrate 1b
chr13_-_31491759 1.33 ENSDART00000057432
SIX homeobox 1a
chr1_-_40208469 1.29 ENSDART00000027463
H6 family homeobox 4
chr18_-_13153360 1.27 ENSDART00000092648
transmembrane protein 5
chr12_+_42281025 1.27 ENSDART00000167324
early B-cell factor 3a
chr7_+_19895162 1.26 ENSDART00000011398
si:ch73-335l21.1
chr2_+_27344633 1.26 ENSDART00000178275
cadherin 7, type 2
chr11_-_44724371 1.25 ENSDART00000166501
calcium activated nucleotidase 1b
chr6_+_43236843 1.21 ENSDART00000112474
ADP-ribosylation factor-like 6 interacting protein 5a
chr5_+_48031920 1.19 ENSDART00000008043
ENSDART00000171438
adhesion G protein-coupled receptor V1
chr14_-_47083485 1.16 ENSDART00000172512
E74-like factor 2a (ets domain transcription factor)
chr24_+_19374200 1.14 ENSDART00000056081
ENSDART00000027022
sulfatase 1
chr9_+_34832049 1.10 ENSDART00000100735
ENSDART00000133996
short stature homeobox
chr24_-_38496534 1.03 ENSDART00000140739
leucine rich repeat containing 4Bb
chr18_+_23891068 1.00 ENSDART00000146490
ENSDARG00000092402
chr21_-_44109455 0.99 ENSDART00000044599
organic anion transporter X
chr13_-_29290894 0.97 ENSDART00000150228
choline O-acetyltransferase a
chr5_+_50432868 0.95 ENSDART00000097466
family with sequence similarity 169, member Aa
chr9_-_51975919 0.93 ENSDART00000006612
T-box, brain, 1b
chr23_-_24755654 0.90 ENSDART00000104035
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr2_-_49114158 0.90

chr24_-_23797468 0.86 ENSDART00000080810
aristaless related homeobox a
chr2_-_42222069 0.86 ENSDART00000142792
centrosome and spindle pole associated protein 1b
chr24_+_19374099 0.82 ENSDART00000056081
ENSDART00000027022
sulfatase 1
chr14_-_16791447 0.81 ENSDART00000158002
ENSDARG00000103278
chr25_+_4918339 0.80 ENSDART00000153980
parvin, beta
chr6_+_6767424 0.77 ENSDART00000065551
ENSDART00000151393
sterile alpha motif and leucine zipper containing kinase AZK
chr21_-_28883441 0.75 ENSDART00000132884
CXXC finger protein 5a
chr14_-_24304373 0.75

chr18_+_23891152 0.75 ENSDART00000146490
ENSDARG00000092402
chr19_-_35739239 0.71

chr3_-_26657213 0.69

chr7_+_13753344 0.68

chr6_+_8895437 0.66 ENSDART00000162588
regucalcin
chr23_-_12410797 0.65 ENSDART00000133956
phosphatase and actin regulator 3a
chr12_+_17382681 0.65 ENSDART00000020628
cytohesin 3a
chr14_-_16762869 0.64 ENSDART00000163766
paired-like homeobox 2bb
chr2_-_20490037 0.64 ENSDART00000160388
ENSDARG00000101927
chr13_+_33378267 0.61 ENSDART00000025007
jagged 2a
chr13_+_14845093 0.61 ENSDART00000011520
notochord homeobox
chr23_-_10906094 0.60

chr18_+_23890892 0.58 ENSDART00000146490
ENSDARG00000092402
chr15_+_22499643 0.58 ENSDART00000031976
transmembrane protein 136a
chr6_+_40664212 0.57 ENSDART00000103842
enolase 1b, (alpha)
chr14_-_16762762 0.54 ENSDART00000106333
paired-like homeobox 2bb
chr14_-_21854679 0.54 ENSDART00000115422
NudC domain containing 2
chr24_+_30343717 0.53 ENSDART00000162377
ENSDARG00000100270
chr16_-_31763281 0.53 ENSDART00000169109
retinol binding protein 1a, cellular
chr3_+_3923243 0.52 ENSDART00000104977
protein interacting with prkca 1
chr11_-_37158131 0.50 ENSDART00000160911
ELKS/RAB6-interacting/CAST family member 2
chr13_+_18376642 0.49 ENSDART00000142622
si:ch211-198a12.6
chr19_+_16160028 0.49 ENSDART00000144376
glucocorticoid modulatory element binding protein 1
chr23_+_28564630 0.47

chr23_+_5899604 0.42

chr5_-_23709401 0.40

chr12_-_34612821 0.39 ENSDART00000153272
BAH domain and coiled-coil containing 1b
chr13_-_49707003 0.39

chr22_+_37688585 0.39 ENSDART00000174664
ENSDART00000178200
ENSDARG00000108910
chr10_+_9259213 0.38 ENSDART00000064966
sorting nexin 18b
chr20_-_29028920 0.38 ENSDART00000153082
sushi domain containing 6
chr24_-_21750082 0.38

chr7_+_71757218 0.38 ENSDART00000012918
proteasome 26S subunit, non-ATPase 9
chr14_-_20826302 0.37 ENSDART00000171679
si:dkey-74k8.4
chr13_+_49154065 0.37

chr23_-_36342779 0.33 ENSDART00000024354
cysteine sulfinic acid decarboxylase
chr7_+_28896401 0.32 ENSDART00000076345
solute carrier family 38, member 8b
chr3_+_29314649 0.30 ENSDART00000020381
GRB2-related adaptor protein 2a
chr8_-_17130805 0.30

chr24_+_30343687 0.30 ENSDART00000162377
ENSDARG00000100270
chr24_+_24924379 0.29 ENSDART00000115165
APC membrane recruitment protein 2
chr1_+_45843326 0.28

KN149962v1_-_109672 0.28

chr17_-_12812747 0.27 ENSDART00000022874
ENSDART00000046025
proteasome subunit alpha 6a
chr14_-_34265449 0.27 ENSDART00000144547
actin filament associated protein 1-like 1a
chr7_+_21592861 0.26 ENSDART00000159626
si:dkey-85k7.7
chr1_+_18118995 0.26 ENSDART00000078610
solute carrier family 25, member 51a
chr14_-_24113237 0.25 ENSDART00000125923
chemokine (C-X-C motif) ligand 14
chr20_+_10179249 0.24 ENSDART00000141877
potassium channel, subfamily K, member 10a
chr21_-_10354049 0.23 ENSDART00000159958
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr20_-_43878454 0.22 ENSDART00000100610
ENSDART00000100608
ENSDART00000148809
matrilin 3a
chr20_+_31384580 0.22 ENSDART00000007688
solute carrier family 22 (organic cation/carnitine transporter), member 16
chr3_-_30948297 0.22 ENSDART00000145636
elongin B
chr7_+_38540519 0.22 ENSDART00000052322
zgc:110699
chr3_-_13771322 0.21 ENSDART00000159177
ENSDART00000165174
si:dkey-61n16.5
chr24_-_17089437 0.20

chr12_+_42281154 0.19 ENSDART00000167324
early B-cell factor 3a
chr9_-_27838603 0.19

chr1_+_37423689 0.18 ENSDART00000079928
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr13_+_46487890 0.18

chr10_+_22538287 0.18 ENSDART00000109070
GRB10 interacting GYF protein 1b
chr22_+_17409030 0.18 ENSDART00000139523
RAB GTPase activating protein 1-like
chr7_+_38540586 0.17 ENSDART00000052322
zgc:110699
chr3_+_31047152 0.16

chr21_-_28883243 0.15 ENSDART00000132884
CXXC finger protein 5a
chr19_-_35739013 0.12

chr20_-_21031592 0.11 ENSDART00000152726
BTB (POZ) domain containing 6b
chr2_+_20946939 0.10 ENSDART00000128505
olfactomedin-like 2Bb
chr1_-_55195428 0.10 ENSDART00000019936
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b
chr9_-_48709908 0.09 ENSDART00000058248
ENSDARG00000039824
chr14_+_6308806 0.09 ENSDART00000139292
si:dkeyp-44a8.2
chr8_-_18167468 0.08 ENSDART00000137005
ELOVL fatty acid elongase 8b
chr1_+_25110899 0.08 ENSDART00000129471
guanylate cyclase 1, soluble, beta 3
chr14_-_29518685 0.08 ENSDART00000136380
sorbin and SH3 domain containing 2b
chr8_-_18167570 0.08 ENSDART00000142114
ELOVL fatty acid elongase 8b
chr9_-_9727433 0.07 ENSDART00000149021
G protein-coupled receptor 156
chr9_-_51976213 0.07 ENSDART00000006612
T-box, brain, 1b
chr15_+_8791540 0.06 ENSDART00000033871
adaptor-related protein complex 2, sigma 1 subunit
chr1_+_37423518 0.06 ENSDART00000079928
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr2_+_52225276 0.05 ENSDART00000170353
ENSDARG00000103108
chr2_+_29729161 0.05 ENSDART00000141666
ENSDARG00000093205
chr19_+_42658273 0.05 ENSDART00000131574
ENSDART00000135436
jumping translocation breakpoint
chr15_-_5732737 0.04 ENSDART00000109599
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
chr2_-_14938196 0.04 ENSDART00000170687
phosphodiesterase 4B, cAMP-specific b
chr14_-_21717949 0.04 ENSDART00000137795
structure specific recognition protein 1a
chr5_+_31889674 0.03 ENSDART00000165417
NADPH dependent diflavin oxidoreductase 1
chr22_-_15666856 0.03 ENSDART00000141861
si:ch1073-396h14.1
chr5_-_68408171 0.03 ENSDART00000109761
ENSDART00000156681
ENSDART00000167680
ENSDARG00000076888
chr10_-_33677866 0.02 ENSDART00000142655
hormonally up-regulated Neu-associated kinase
chr20_-_43281081 0.01

chr8_+_35483042 0.00 ENSDART00000111021
si:dkeyp-14d3.1
chr17_-_45140696 0.00

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.8 3.1 GO:0048025 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.6 5.8 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.6 1.7 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.5 1.6 GO:0061130 branching involved in pancreas morphogenesis(GO:0061114) pancreatic bud formation(GO:0061130) pancreas field specification(GO:0061131)
0.5 2.0 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.4 1.2 GO:0030818 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclic nucleotide metabolic process(GO:0030800) negative regulation of cyclic nucleotide biosynthetic process(GO:0030803) negative regulation of nucleotide biosynthetic process(GO:0030809) negative regulation of cAMP metabolic process(GO:0030815) negative regulation of cAMP biosynthetic process(GO:0030818) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350) negative regulation of purine nucleotide biosynthetic process(GO:1900372)
0.4 1.2 GO:0061549 sympathetic ganglion development(GO:0061549)
0.4 1.6 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.3 1.0 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.3 1.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.3 1.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 2.9 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.2 0.9 GO:0003322 pancreatic A cell development(GO:0003322)
0.2 1.4 GO:0044458 motile cilium assembly(GO:0044458)
0.2 1.3 GO:0014857 skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857)
0.2 1.6 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.2 2.0 GO:0021767 mammillary body development(GO:0021767)
0.2 0.7 GO:0019852 L-ascorbic acid metabolic process(GO:0019852) water-soluble vitamin biosynthetic process(GO:0042364) regulation of calcium-mediated signaling(GO:0050848)
0.2 2.1 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.6 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 0.6 GO:0021982 pineal gland development(GO:0021982)
0.1 0.5 GO:0002090 regulation of receptor internalization(GO:0002090)
0.1 0.9 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.2 GO:0015695 organic cation transport(GO:0015695)
0.1 1.3 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 1.3 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.8 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 1.1 GO:0030282 bone mineralization(GO:0030282)
0.0 0.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.3 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 1.9 GO:0006936 muscle contraction(GO:0006936)
0.0 0.3 GO:0007398 ectoderm development(GO:0007398)
0.0 0.7 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.3 GO:0003333 amino acid transmembrane transport(GO:0003333)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0042627 chylomicron(GO:0042627)
0.2 1.2 GO:0001917 photoreceptor inner segment(GO:0001917) stereocilium(GO:0032420)
0.2 1.7 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.2 1.9 GO:0031430 M band(GO:0031430)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.5 GO:0098842 postsynaptic early endosome(GO:0098842)
0.1 0.5 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.0 1.4 GO:0030175 filopodium(GO:0030175)
0.0 2.0 GO:0005795 Golgi stack(GO:0005795)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.8 GO:0030018 Z disc(GO:0030018)
0.0 1.3 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0038039 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.9 GO:0000922 spindle pole(GO:0000922)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.8 GO:0008263 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.5 3.3 GO:0016918 retinal binding(GO:0016918)
0.2 2.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 1.6 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.2 1.7 GO:0051117 ATPase binding(GO:0051117)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.5 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 1.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.3 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.2 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 1.0 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 1.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.9 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.5 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.3 GO:0042379 chemokine activity(GO:0008009) chemokine receptor binding(GO:0042379)
0.0 0.2 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 2.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 1.9 GO:0019900 kinase binding(GO:0019900)
0.0 0.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 16.1 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.3 GO:0016831 carboxy-lyase activity(GO:0016831)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 0.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 3.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 2.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.6 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 0.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)