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Results for atf2_atf1_atf3_crema+cremb

Z-value: 3.06

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Transcription factors associated with atf2_atf1_atf3_crema+cremb

Gene Symbol Gene ID Gene Info
ENSDARG00000023903 activating transcription factor 2
ENSDARG00000044301 activating transcription factor 1
ENSDARG00000007823 activating transcription factor 3
ENSDARG00000023217 cAMP responsive element modulator a
ENSDARG00000102899 cAMP responsive element modulator b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
atf3dr10_dc_chr20_+_37891739_378917470.885.7e-06Click!
cremadr10_dc_chr2_-_43318809_43318849-0.871.1e-05Click!
atf1dr10_dc_chr6_-_39524075_395242960.853.4e-05Click!
atf2dr10_dc_chr9_+_2346341_2346400-0.581.7e-02Click!

Activity profile of atf2_atf1_atf3_crema+cremb motif

Sorted Z-values of atf2_atf1_atf3_crema+cremb motif

Network of associatons between targets according to the STRING database.

First level regulatory network of atf2_atf1_atf3_crema+cremb

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr25_-_36512943 9.31 ENSDART00000114508
hypoxanthine phosphoribosyltransferase 1, like
chr24_-_19573615 8.95 ENSDART00000158952
ENSDART00000109107
ENSDART00000056082
cysteine-serine-rich nuclear protein 1b
chr11_-_44539778 8.03 ENSDART00000161846
microtubule-associated protein 1 light chain 3 gamma
chr8_-_410190 8.00 ENSDART00000151155
tripartite motif containing 36
chr7_+_17848688 7.45 ENSDART00000055810
zRAB1B, member RAS oncogene family a
chr17_+_25168837 7.40 ENSDART00000148431
CLN8, transmembrane ER and ERGIC protein
chr25_+_34340569 7.16 ENSDART00000157638
transmembrane protein 231
chr2_+_35621136 7.02 ENSDART00000133018
ENSDART00000147278
polo-like kinase 3 (Drosophila)
chr24_-_19573966 6.90 ENSDART00000158952
ENSDART00000109107
ENSDART00000056082
cysteine-serine-rich nuclear protein 1b
chr19_+_14592632 6.85 ENSDART00000161088
ENSDART00000161965
zinc finger, DHHC-type containing 18b
chr2_-_57020663 6.78

chr7_-_19989384 6.77 ENSDART00000173619
si:ch73-335l21.4
chr5_-_28931727 6.61 ENSDART00000174697
arrestin domain containing 1a
chr17_+_52526741 6.59 ENSDART00000109891
angel homolog 1 (Drosophila)
chr16_-_41585481 6.58 ENSDART00000102662
ribonuclease P/MRP 25 subunit-like
chr10_-_34971985 6.50 ENSDART00000141201
cyclin A1
chr14_+_29945327 6.14 ENSDART00000173090
microtubule associated tumor suppressor 1a
chr7_-_51497945 6.10 ENSDART00000054591
bone morphogenetic protein 15
chr22_+_24596299 6.02 ENSDART00000158303
ENSDART00000160924
mucolipin 2
chr4_-_16639774 6.00 ENSDART00000125323
caprin family member 2
chr16_-_42116471 5.94 ENSDART00000058620
zona pellucida glycoprotein 3d tandem duplicate 1
chr8_+_52456064 5.77 ENSDART00000012758
zgc:77112
chr22_+_1500412 5.76 ENSDART00000160406
si:ch211-255f4.5
chr15_+_5125138 5.68 ENSDART00000101937
phosphoglucomutase 2-like 1
chr10_+_7634671 5.66 ENSDART00000171744
protein phosphatase 2, catalytic subunit, beta isozyme
chr23_-_1562572 5.42 ENSDART00000013635
F-box protein 30b
chr17_-_24684870 5.41 ENSDART00000156061
si:ch211-15d5.12
chr23_+_20586745 5.38 ENSDART00000157522
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
KN150030v1_-_22572 5.37 ENSDART00000175410
ENSDARG00000106760
chr2_-_31817448 5.35 ENSDART00000170880
reticulophagy regulator 1
chr20_-_20921480 5.31 ENSDART00000152781
creatine kinase, brain b
chr22_+_1837102 5.24 ENSDART00000163288
zinc finger protein 1174
chr12_-_24711074 4.99 ENSDART00000066317
forkhead box N2b
chr10_+_15644868 4.91 ENSDART00000139259
zinc finger, AN1-type domain 5b
chr24_+_12845339 4.89 ENSDART00000126842
hypothetical protein FLJ11011-like (H. sapiens)
chr8_-_410293 4.83 ENSDART00000164886
tripartite motif containing 36
chr17_+_27988842 4.62 ENSDART00000155838
leucine zipper protein 1
chr13_+_51485084 4.60 ENSDART00000163741
PWWP domain containing 2B
chr2_-_31817409 4.54 ENSDART00000112763
reticulophagy regulator 1
chr11_+_36117256 4.52 ENSDART00000141529
ataxin 7-like 2a
chr16_-_55210909 4.52 ENSDART00000156533
keratinocyte differentiation factor 1a
chr12_-_17741377 4.52 ENSDART00000166604
BAI1-associated protein 2-like 1a
chr14_-_745312 4.52 ENSDART00000049918
ENSDART00000165856
tripartite motif containing 35-27
chr2_+_9762781 4.46 ENSDART00000003465
GIPC PDZ domain containing family, member 2
chr19_+_14592246 4.43 ENSDART00000161088
ENSDART00000161965
zinc finger, DHHC-type containing 18b
chr15_+_5124690 4.42 ENSDART00000101937
phosphoglucomutase 2-like 1
chr16_-_5205600 4.39 ENSDART00000148955
branched chain keto acid dehydrogenase E1, beta polypeptide
chr6_+_94581 4.37 ENSDART00000125176
adaptor-related protein complex 1, mu 2 subunit
chr19_+_10742944 4.33 ENSDART00000165653
argonaute RISC catalytic component 3b
chr7_-_19989419 4.32 ENSDART00000127699
si:ch73-335l21.4
chr15_+_5124897 4.31 ENSDART00000101937
phosphoglucomutase 2-like 1
chr2_-_57020490 4.27

chr18_-_5167807 4.27

chr11_-_44859225 4.21 ENSDART00000163776
eukaryotic translation initiation factor 4A3
chr25_-_34340016 4.21 ENSDART00000039485
GABA(A) receptor-associated protein like 2
chr7_+_10319999 4.19 ENSDART00000168801
zinc finger, AN1-type domain 6
chr1_-_54391298 4.16 ENSDART00000152143
ENSDART00000152590
pellino E3 ubiquitin protein ligase 1a
chr17_+_23534953 4.12 ENSDART00000135814
pantothenate kinase 1a
chr17_+_15527923 3.98 ENSDART00000148443
myristoylated alanine-rich protein kinase C substrate b
chr13_+_8508786 3.95 ENSDART00000059321
epithelial cell adhesion molecule
chr20_+_46668743 3.95 ENSDART00000139051
ENSDART00000161320
basic leucine zipper transcription factor, ATF-like
chr14_-_41101660 3.94 ENSDART00000003170
MID1 interacting protein 1, like
chr12_-_10474942 3.89 ENSDART00000106163
ENSDART00000124562
zgc:152977
chr6_+_40994859 3.84 ENSDART00000151419
transforming growth factor, alpha
chr23_-_10850891 3.79

chr15_+_37644266 3.71 ENSDART00000099456
presenilin enhancer gamma secretase subunit
chr9_-_27585644 3.70 ENSDART00000101401
testis expressed 30
chr25_-_31352866 3.70 ENSDART00000041740
ubiquitin-like 7a (bone marrow stromal cell-derived)
chr2_+_9762627 3.68 ENSDART00000003465
GIPC PDZ domain containing family, member 2
chr1_-_17000212 3.66 ENSDART00000146258
cilia and flagella associated protein 97
chr17_-_31195299 3.65 ENSDART00000086511
RNA pseudouridylate synthase domain containing 2
chr10_+_44456550 3.65 ENSDART00000157611
small nuclear ribonucleoprotein 35 (U11/U12)
chr3_+_16772351 3.62 ENSDART00000164895
ATPase, H+ transporting, lysosomal V0 subunit a1a
chr6_+_40994918 3.61 ENSDART00000151419
transforming growth factor, alpha
chr20_-_3301951 3.59 ENSDART00000123096
myristoylated alanine-rich protein kinase C substrate a
chr7_+_69211965 3.59 ENSDART00000028064
CTD nuclear envelope phosphatase 1b
chr5_-_9035789 3.59 ENSDART00000124384
cyclin G associated kinase
chr16_-_55211053 3.55 ENSDART00000156533
keratinocyte differentiation factor 1a
chr18_+_18890626 3.52 ENSDART00000019581
ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)
chr9_-_25555313 3.52 ENSDART00000021672
enhancer of polycomb homolog 2 (Drosophila)
KN150030v1_-_22613 3.52 ENSDART00000175410
ENSDARG00000106760
chr21_-_25991335 3.51 ENSDART00000034875
stromal cell-derived factor 2
chr6_+_27676886 3.50 ENSDART00000159624
ENSDART00000049177
RAB6B, member RAS oncogene family a
chr22_-_26971170 3.50 ENSDART00000162742
ENSDARG00000061256
chr17_+_25163592 3.43 ENSDART00000100277
CLN8, transmembrane ER and ERGIC protein
chr21_-_25991445 3.43 ENSDART00000034875
stromal cell-derived factor 2
chr4_-_14916491 3.43 ENSDART00000067040
si:dkey-180p18.9
chr8_-_38284959 3.41 ENSDART00000125920
PDZ and LIM domain 2 (mystique)
KN150455v1_-_14200 3.41

chr22_+_1153361 3.41 ENSDART00000159761
interferon regulatory factor 6
chr5_+_56988663 3.41 ENSDART00000074268
zgc:153929
chr4_-_25526284 3.40 ENSDART00000142276
RNA binding motif protein 17
chr22_+_2422443 3.39

chr16_-_34471672 3.38 ENSDART00000172162
ENSDARG00000105308
chr2_-_37495925 3.38 ENSDART00000146103
death-associated protein kinase 3
chr7_+_1443102 3.34 ENSDART00000172830
SPT16 homolog, facilitates chromatin remodeling subunit
chr8_+_23704663 3.33 ENSDART00000104346
makorin, ring finger protein, 4
chr19_-_12728868 3.33 ENSDART00000103692
family with sequence similarity 210, member Aa
chr23_-_25760917 3.32

chr23_-_27579257 3.31 ENSDART00000137229
ankyrin repeat and SOCS box containing 8
chr20_+_37891739 3.30 ENSDART00000022060
activating transcription factor 3
chr8_+_29733037 3.28 ENSDART00000133955
mitogen-activated protein kinase 4
chr4_-_14916416 3.25 ENSDART00000067040
si:dkey-180p18.9
chr7_+_66410533 3.24 ENSDART00000027616
ENSDART00000162763
eukaryotic translation initiation factor 4, gamma 2a
chr2_-_4191540 3.24 ENSDART00000158335
RAB18B, member RAS oncogene family
chr7_+_45747622 3.24 ENSDART00000163991
cyclin E1
chr24_-_16835352 3.24 ENSDART00000005331
ENSDART00000128446
kelch-like family member 15
chr3_+_33608070 3.20

chr10_-_34971926 3.19 ENSDART00000141201
cyclin A1
chr16_-_29452509 3.19 ENSDART00000148787
S100 calcium binding protein A1
chr23_+_10870124 3.19 ENSDART00000035693
protein phosphatase 4, regulatory subunit 2a
chr13_-_49749441 3.19 ENSDART00000136165
lysosomal trafficking regulator
chr13_+_404116 3.17 ENSDART00000147909
wu:fc17b08
chr19_+_14592518 3.17 ENSDART00000161088
ENSDART00000161965
zinc finger, DHHC-type containing 18b
chr19_+_43090603 3.16 ENSDART00000018328
F-box and leucine-rich repeat protein 2
chr7_+_45747395 3.14 ENSDART00000163991
cyclin E1
chr4_+_74723809 3.13 ENSDART00000172734
si:ch73-389k6.1
chr5_-_68011971 3.12 ENSDART00000141699
methylphosphate capping enzyme
chr4_-_71752866 3.12 ENSDART00000143417
ENSDART00000172042
zgc:162958
chr6_+_40995061 3.11 ENSDART00000151419
transforming growth factor, alpha
chr3_-_16263615 3.10 ENSDART00000127309
elongation factor Tu GTP binding domain containing 2
chr25_-_6320310 3.10 ENSDART00000139606
snurportin 1
chr13_-_36312975 3.08 ENSDART00000084867
ddb1 and cul4 associated factor 5
chr21_-_25991595 3.08 ENSDART00000034875
stromal cell-derived factor 2
chr17_+_15527861 3.07 ENSDART00000148443
myristoylated alanine-rich protein kinase C substrate b
chr2_-_56511961 3.06 ENSDART00000168160
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma b
chr12_-_22116694 3.06 ENSDART00000038310
ENSDART00000132731
ORMDL sphingolipid biosynthesis regulator 3
chr6_+_59580554 3.06

chr23_-_29952057 3.05 ENSDART00000058407
solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr12_-_17741310 3.03 ENSDART00000166604
BAI1-associated protein 2-like 1a
chr17_-_31195376 3.03 ENSDART00000086511
RNA pseudouridylate synthase domain containing 2
chr9_+_42744889 3.02

chr17_+_23534824 3.02 ENSDART00000135814
pantothenate kinase 1a
chr12_-_926596 3.00 ENSDART00000088351
sperm associated antigen 9
chr5_-_37655292 3.00 ENSDART00000156291
ENSDARG00000096962
chr10_+_32702525 2.99 ENSDART00000137244
zinc finger and BTB domain containing 21
chr23_+_23256896 2.98 ENSDART00000132296
kelch-like family member 17
chr17_-_22552999 2.97 ENSDART00000141523
exonuclease 1
chr3_-_18039574 2.97 ENSDART00000049240
transducer of ERBB2, 1a
chr22_+_1445227 2.96 ENSDART00000164685
si:dkeyp-53d3.5
chr6_+_19167599 2.94 ENSDART00000086619
protein kinase C, alpha
chr19_+_27338879 2.94 ENSDART00000149988
negative elongation factor complex member E
chr2_-_6380292 2.94 ENSDART00000092182
protein phosphatase, Mg2+/Mn2+ dependent, 1La
chr6_-_54436651 2.94 ENSDART00000154121
Sys1 golgi trafficking protein
chr22_-_760140 2.93 ENSDART00000019155
B-cell translocation gene 2
chr3_-_45358502 2.92 ENSDART00000168108
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a
chr5_+_61711614 2.90 ENSDART00000082965
active BCR-related
chr23_+_33792145 2.90 ENSDART00000024695
DAZ associated protein 2
chr15_+_5124616 2.88 ENSDART00000101937
phosphoglucomutase 2-like 1
chr12_-_10384031 2.83 ENSDART00000052004
zgc:153595
chr18_+_6417959 2.82 ENSDART00000110892
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr17_+_15527525 2.82 ENSDART00000159426
myristoylated alanine-rich protein kinase C substrate b
chr21_+_3624059 2.82 ENSDART00000111699
torsin family 1
chr16_-_41585555 2.82 ENSDART00000131706
ribonuclease P/MRP 25 subunit-like
chr21_+_3764216 2.79 ENSDART00000149777
senataxin
chr7_+_10320142 2.79 ENSDART00000168801
zinc finger, AN1-type domain 6
chr25_-_22954929 2.78 ENSDART00000024633
dual specificity phosphatase 8a
chr10_+_14530451 2.78 ENSDART00000026383
sigma non-opioid intracellular receptor 1
chr5_+_12971972 2.78 ENSDART00000132406
cyclin and CBS domain divalent metal cation transport mediator 4b
chr12_-_24711169 2.78 ENSDART00000066317
forkhead box N2b
chr3_-_30778382 2.78 ENSDART00000025046
protein phosphatase 1, catalytic subunit, alpha isozyme a
chr7_+_28341426 2.78 ENSDART00000019991
solute carrier family 7, member 6 opposite strand
chr5_+_71360249 2.78

chr19_+_14592757 2.77 ENSDART00000161088
ENSDART00000161965
zinc finger, DHHC-type containing 18b
chr8_-_38284748 2.77 ENSDART00000102233
PDZ and LIM domain 2 (mystique)
chr12_+_33793663 2.77 ENSDART00000004769
major facilitator superfamily domain containing 13A
chr2_+_22753634 2.76 ENSDART00000171853
zgc:56628
chr15_-_41732606 2.76 ENSDART00000059327
splA/ryanodine receptor domain and SOCS box containing 4b
chr10_+_27028355 2.75 ENSDART00000064111
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed b
chr6_-_10677028 2.75 ENSDART00000036456
cytochrome c, somatic b
chr5_-_9036049 2.73 ENSDART00000160079
cyclin G associated kinase
chr4_+_9010972 2.73 ENSDART00000058007
sorting and assembly machinery component 50 homolog, like
chr1_+_9621488 2.73 ENSDART00000043881
zgc:77880
chr10_-_2944190 2.72 ENSDART00000132526
MARVEL domain containing 2a
chr17_-_7635061 2.72 ENSDART00000064655
zinc finger and BTB domain containing 2a
chr11_-_13283709 2.71 ENSDART00000164978
microtubule associated serine/threonine kinase 3b
KN150699v1_-_15078 2.71 ENSDART00000159861
ENSDARG00000098739
chr10_-_6587281 2.69 ENSDART00000163788
ENSDART00000171833
chromodomain helicase DNA binding protein 1
chr14_+_31278584 2.69 ENSDART00000158875
ENSDART00000026195
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6a
chr17_+_27988973 2.68 ENSDART00000155838
leucine zipper protein 1
chr25_-_36513113 2.67 ENSDART00000025494
hypoxanthine phosphoribosyltransferase 1, like
chr15_-_29229170 2.67 ENSDART00000138449
XIAP associated factor 1
chr7_+_37818298 2.67 ENSDART00000052365
CCAAT/enhancer binding protein (C/EBP), gamma
chr18_-_16964811 2.65 ENSDART00000100126
A kinase (PRKA) interacting protein 1
chr11_-_22663375 2.65 ENSDART00000154813
MDM4, p53 regulator
chr18_+_22804127 2.64 ENSDART00000149685
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a
chr23_+_17583383 2.64 ENSDART00000148457
GID complex subunit 8 homolog b (S. cerevisiae)
chr15_-_778461 2.64 ENSDART00000153874
si:dkey-7i4.19
chr23_+_23256859 2.64 ENSDART00000132296
kelch-like family member 17
chr8_-_38284904 2.64 ENSDART00000125920
PDZ and LIM domain 2 (mystique)
chr22_+_3167367 2.62 ENSDART00000160604
FtsJ homolog 3 (E. coli)
chr19_-_3547196 2.62 ENSDART00000166107
human immunodeficiency virus type I enhancer binding protein 1
chr3_-_40791035 2.60 ENSDART00000055201
forkhead box K1
chr20_-_3301898 2.59 ENSDART00000123096
myristoylated alanine-rich protein kinase C substrate a
chr20_-_44678938 2.59 ENSDART00000148639
UBX domain protein 2A
chr8_-_16638825 2.58 ENSDART00000100727
oxysterol binding protein-like 9
chr12_+_46853062 2.56 ENSDART00000171146
4-hydroxyphenylpyruvate dioxygenase-like
chr22_-_10861268 2.55 ENSDART00000145229
rho/rac guanine nucleotide exchange factor (GEF) 18b
chr22_+_1451958 2.55

chr24_+_16838877 2.55 ENSDART00000145520
eukaryotic translation initiation factor 2, subunit 3 gamma

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 9.9 GO:1900144 epithelial cell morphogenesis involved in gastrulation(GO:0003381) BMP secretion(GO:0038055) positive regulation of BMP secretion(GO:1900144) regulation of BMP secretion(GO:2001284)
3.0 12.0 GO:0006178 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine metabolic process(GO:0046098) guanine biosynthetic process(GO:0046099) hypoxanthine metabolic process(GO:0046100)
2.3 7.0 GO:0090166 Golgi disassembly(GO:0090166)
2.2 8.7 GO:0003334 keratinocyte development(GO:0003334)
1.6 7.8 GO:0072319 clathrin coat disassembly(GO:0072318) vesicle uncoating(GO:0072319)
1.5 12.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
1.5 6.1 GO:0001541 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698)
1.5 6.0 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
1.5 16.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
1.5 5.8 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
1.5 2.9 GO:0071331 cellular glucose homeostasis(GO:0001678) cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
1.3 9.2 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
1.3 3.9 GO:0072540 T-helper cell lineage commitment(GO:0002295) T cell lineage commitment(GO:0002360) alpha-beta T cell lineage commitment(GO:0002363) type 2 immune response(GO:0042092) positive T cell selection(GO:0043368) CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) T cell selection(GO:0045058) T-helper 2 cell differentiation(GO:0045064) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540)
1.2 9.9 GO:0001682 tRNA 5'-leader removal(GO:0001682)
1.2 9.5 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
1.1 4.5 GO:0030730 regulation of sequestering of triglyceride(GO:0010889) positive regulation of sequestering of triglyceride(GO:0010890) sequestering of triglyceride(GO:0030730)
1.0 4.2 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
1.0 3.1 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
1.0 3.1 GO:0061015 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
1.0 3.1 GO:1905038 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
1.0 6.1 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
1.0 2.9 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
1.0 2.9 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.9 7.6 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249) positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.9 2.8 GO:0071763 nuclear membrane organization(GO:0071763)
0.9 3.7 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.9 3.7 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.9 4.4 GO:0032516 positive regulation of phosphatase activity(GO:0010922) positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.9 2.7 GO:0006408 snRNA export from nucleus(GO:0006408) regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833) snRNA transport(GO:0051030)
0.9 4.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.9 2.6 GO:0070476 rRNA (guanine-N7)-methylation(GO:0070476)
0.8 0.8 GO:1990564 protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.8 0.8 GO:0034727 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) single-organism membrane invagination(GO:1902534)
0.8 6.4 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.8 2.4 GO:0021861 forebrain radial glial cell differentiation(GO:0021861)
0.7 23.8 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.7 2.8 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.7 4.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.7 9.9 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.6 8.4 GO:0061709 reticulophagy(GO:0061709)
0.6 1.9 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.6 2.5 GO:1902224 cellular ketone body metabolic process(GO:0046950) ketone body metabolic process(GO:1902224)
0.6 3.1 GO:1900182 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.6 2.3 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.6 2.3 GO:0045980 negative regulation of nucleotide metabolic process(GO:0045980) negative regulation of purine nucleotide metabolic process(GO:1900543)
0.6 2.3 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.6 4.0 GO:0090049 regulation of cell migration involved in sprouting angiogenesis(GO:0090049)
0.6 2.8 GO:0034205 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.6 5.0 GO:0090382 phagosome maturation(GO:0090382)
0.5 8.0 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.5 5.3 GO:0070932 histone H3 deacetylation(GO:0070932)
0.5 10.5 GO:0006998 nuclear envelope organization(GO:0006998)
0.5 3.2 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.5 5.7 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.5 2.6 GO:0038171 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.5 3.6 GO:0070987 error-free translesion synthesis(GO:0070987)
0.5 2.5 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.5 4.0 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.5 2.9 GO:0006895 Golgi to endosome transport(GO:0006895)
0.5 1.5 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.5 2.4 GO:1901976 regulation of cell cycle checkpoint(GO:1901976)
0.5 0.5 GO:0060143 positive regulation of syncytium formation by plasma membrane fusion(GO:0060143) positive regulation of myoblast fusion(GO:1901741)
0.5 2.9 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.5 2.9 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.5 3.8 GO:0034389 lipid particle organization(GO:0034389)
0.5 2.8 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.5 1.9 GO:0072575 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.5 1.9 GO:0015882 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.5 3.7 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.5 3.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.4 1.8 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.4 4.0 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.4 3.6 GO:1901031 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.4 1.3 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded DNA demethylation(GO:0035552)
0.4 2.5 GO:0048608 gonad development(GO:0008406) reproductive structure development(GO:0048608) reproductive system development(GO:0061458)
0.4 8.0 GO:0032885 regulation of polysaccharide biosynthetic process(GO:0032885)
0.4 0.4 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.4 5.0 GO:0016926 protein desumoylation(GO:0016926)
0.4 0.8 GO:1903429 regulation of cell maturation(GO:1903429)
0.4 6.2 GO:0090559 regulation of membrane permeability(GO:0090559)
0.4 2.4 GO:0097354 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.4 12.6 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.4 3.6 GO:0048532 anatomical structure arrangement(GO:0048532)
0.4 1.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.4 1.2 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.4 2.7 GO:1904666 regulation of ubiquitin protein ligase activity(GO:1904666)
0.4 1.9 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.4 2.6 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.4 1.8 GO:0035313 negative regulation of Rac protein signal transduction(GO:0035021) wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.4 2.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.3 5.9 GO:0007339 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.3 3.1 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.3 2.8 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.3 0.7 GO:0048569 post-embryonic organ development(GO:0048569)
0.3 1.7 GO:0021588 cerebellum formation(GO:0021588)
0.3 6.9 GO:0043574 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.3 8.8 GO:0048263 determination of dorsal identity(GO:0048263)
0.3 4.3 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.3 1.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.3 1.3 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.3 1.3 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.3 0.9 GO:0070640 vitamin D3 metabolic process(GO:0070640)
0.3 1.8 GO:0021550 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.3 2.0 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.3 3.7 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.3 3.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.3 2.0 GO:0055015 ventricular cardiac muscle cell differentiation(GO:0055012) ventricular cardiac muscle cell development(GO:0055015)
0.3 5.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.3 10.0 GO:0055088 lipid homeostasis(GO:0055088)
0.3 2.2 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.3 0.8 GO:0048103 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
0.3 1.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.3 1.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.3 12.4 GO:0030901 midbrain development(GO:0030901)
0.3 0.5 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.3 4.3 GO:0072091 regulation of stem cell proliferation(GO:0072091)
0.3 0.8 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.2 0.7 GO:0072501 cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320) cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2 2.2 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.2 3.4 GO:0048669 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.2 12.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.2 0.7 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 1.4 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.2 11.9 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.2 4.3 GO:0006298 mismatch repair(GO:0006298)
0.2 2.4 GO:0051639 actin filament network formation(GO:0051639)
0.2 1.9 GO:1990108 protein linear deubiquitination(GO:1990108)
0.2 10.0 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.2 0.7 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.2 2.5 GO:0030719 P granule organization(GO:0030719)
0.2 5.3 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.2 3.0 GO:0097320 membrane tubulation(GO:0097320)
0.2 1.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.2 0.7 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.2 1.6 GO:0015740 C4-dicarboxylate transport(GO:0015740)
0.2 2.4 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.2 0.4 GO:0006013 mannose metabolic process(GO:0006013)
0.2 0.9 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 0.6 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.2 0.8 GO:1990379 lysophospholipid transport(GO:0051977) lipid transport across blood brain barrier(GO:1990379)
0.2 0.8 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.2 1.4 GO:0010888 negative regulation of cholesterol storage(GO:0010887) negative regulation of lipid storage(GO:0010888)
0.2 1.4 GO:1901909 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.2 0.6 GO:0042908 xenobiotic transport(GO:0042908)
0.2 0.2 GO:0008298 intracellular mRNA localization(GO:0008298)
0.2 1.0 GO:2000290 regulation of myotome development(GO:2000290)
0.2 1.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.2 1.7 GO:0019682 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.2 1.7 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.2 0.8 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.2 2.1 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.2 0.9 GO:0016540 protein autoprocessing(GO:0016540)
0.2 0.7 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.2 0.7 GO:0046326 positive regulation of glucose import(GO:0046326)
0.2 1.3 GO:0016578 histone deubiquitination(GO:0016578)
0.2 5.8 GO:0044042 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) energy reserve metabolic process(GO:0006112) glucan metabolic process(GO:0044042)
0.2 1.1 GO:0008272 sulfate transport(GO:0008272)
0.2 0.5 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.2 0.3 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.2 2.1 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.2 1.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 1.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.2 0.7 GO:0090161 Golgi ribbon formation(GO:0090161)
0.2 2.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.2 3.8 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.2 2.4 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.2 0.6 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 4.4 GO:0043966 histone H3 acetylation(GO:0043966)
0.2 3.9 GO:0046890 regulation of lipid biosynthetic process(GO:0046890)
0.2 1.6 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.2 0.5 GO:0001955 blood vessel maturation(GO:0001955)
0.2 0.8 GO:0006828 manganese ion transport(GO:0006828)
0.2 0.9 GO:0051589 negative regulation of synaptic transmission(GO:0050805) negative regulation of neurotransmitter transport(GO:0051589)
0.2 0.9 GO:0000012 single strand break repair(GO:0000012)
0.2 1.4 GO:0001709 cell fate determination(GO:0001709)
0.1 0.9 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 0.4 GO:0036010 protein localization to endosome(GO:0036010)
0.1 2.8 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 5.1 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.1 1.7 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.1 5.9 GO:0009615 response to virus(GO:0009615)
0.1 1.1 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 0.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 8.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 0.7 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.9 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479) negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.4 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 1.1 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 0.2 GO:0071548 response to dexamethasone(GO:0071548)
0.1 0.2 GO:0000741 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.1 0.4 GO:0000388 spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)(GO:0000388)
0.1 0.8 GO:0046549 retinal cone cell development(GO:0046549)
0.1 1.7 GO:0006265 DNA topological change(GO:0006265)
0.1 5.9 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.1 1.7 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 1.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.9 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 6.1 GO:0006006 glucose metabolic process(GO:0006006)
0.1 0.6 GO:0000212 meiotic spindle organization(GO:0000212)
0.1 0.3 GO:0051645 Golgi localization(GO:0051645)
0.1 0.8 GO:0006108 malate metabolic process(GO:0006108)
0.1 3.3 GO:0061136 regulation of proteasomal protein catabolic process(GO:0061136)
0.1 0.1 GO:0000423 macromitophagy(GO:0000423)
0.1 1.2 GO:0051351 regulation of ligase activity(GO:0051340) positive regulation of ligase activity(GO:0051351)
0.1 0.6 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 1.4 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 0.7 GO:0060232 delamination(GO:0060232)
0.1 1.1 GO:0008089 anterograde axonal transport(GO:0008089)
0.1 0.3 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 3.5 GO:0060872 semicircular canal development(GO:0060872)
0.1 0.6 GO:0006750 glutathione biosynthetic process(GO:0006750) nonribosomal peptide biosynthetic process(GO:0019184)
0.1 0.7 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.9 GO:0046548 retinal rod cell development(GO:0046548)
0.1 2.2 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.1 2.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 2.0 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 0.4 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 1.7 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 0.3 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.1 0.3 GO:0000493 box H/ACA snoRNP assembly(GO:0000493)
0.1 2.1 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.8 GO:0071025 RNA surveillance(GO:0071025)
0.1 4.8 GO:0055113 epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.1 0.5 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.7 GO:0032467 positive regulation of cytokinesis(GO:0032467) mitotic cell cycle arrest(GO:0071850)
0.1 4.0 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.1 1.5 GO:0006458 'de novo' protein folding(GO:0006458) 'de novo' posttranslational protein folding(GO:0051084) chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 0.3 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627) mitochondrial protein processing(GO:0034982)
0.1 1.0 GO:0009070 serine family amino acid biosynthetic process(GO:0009070)
0.1 0.3 GO:0034505 tooth mineralization(GO:0034505)
0.1 0.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.7 GO:0051310 metaphase plate congression(GO:0051310)
0.1 0.3 GO:0006857 oligopeptide transport(GO:0006857)
0.1 0.6 GO:0030534 adult behavior(GO:0030534)
0.1 1.4 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 2.3 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 0.6 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.2 GO:1903003 regulation of protein deubiquitination(GO:0090085) positive regulation of protein deubiquitination(GO:1903003)
0.1 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 1.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.4 GO:0090200 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 0.4 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 0.5 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.7 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.1 1.8 GO:0009994 oocyte differentiation(GO:0009994) oocyte development(GO:0048599)
0.1 0.6 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.1 1.7 GO:0009408 response to heat(GO:0009408)
0.1 2.3 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.7 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.9 GO:0071428 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.1 1.0 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.2 GO:0071364 response to epidermal growth factor(GO:0070849) cellular response to epidermal growth factor stimulus(GO:0071364)
0.1 0.2 GO:0036503 ERAD pathway(GO:0036503)
0.1 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 1.0 GO:0043588 skin development(GO:0043588)
0.1 6.6 GO:0006413 translational initiation(GO:0006413)
0.1 0.7 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.1 0.8 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.2 GO:2000104 replication fork protection(GO:0048478) negative regulation of DNA-dependent DNA replication(GO:2000104)
0.1 3.2 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.1 2.9 GO:0016573 histone acetylation(GO:0016573)
0.1 0.7 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 0.1 GO:0010259 multicellular organism aging(GO:0010259)
0.1 4.1 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 2.6 GO:0003341 cilium movement(GO:0003341)
0.1 1.1 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 0.1 GO:0048659 smooth muscle cell proliferation(GO:0048659)
0.1 0.6 GO:0031268 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.9 GO:0046466 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.1 0.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.6 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 1.6 GO:0016236 macroautophagy(GO:0016236)
0.0 0.3 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.8 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 1.8 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.4 GO:1902743 regulation of lamellipodium assembly(GO:0010591) regulation of lamellipodium organization(GO:1902743)
0.0 0.0 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 1.5 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 6.7 GO:0006869 lipid transport(GO:0006869)
0.0 0.2 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.0 0.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0000050 urea cycle(GO:0000050) ornithine metabolic process(GO:0006591) urea metabolic process(GO:0019627)
0.0 0.2 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 18.6 GO:0016567 protein ubiquitination(GO:0016567)
0.0 0.5 GO:0009409 response to cold(GO:0009409)
0.0 0.3 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 0.0 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.0 0.6 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.5 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:1903441 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.0 0.9 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 1.6 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.0 0.7 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.3 GO:0009084 glutamine family amino acid biosynthetic process(GO:0009084)
0.0 1.3 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 3.0 GO:0045216 cell-cell junction organization(GO:0045216)
0.0 1.7 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.1 GO:0051792 response to progesterone(GO:0032570) medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 1.4 GO:0051028 mRNA transport(GO:0051028)
0.0 0.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.5 GO:2000779 regulation of double-strand break repair(GO:2000779)
0.0 0.3 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:0060036 notochord cell vacuolation(GO:0060036)
0.0 0.6 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.1 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.0 0.3 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.0 0.7 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.1 GO:0007032 endosome organization(GO:0007032)
0.0 0.4 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.1 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
0.0 0.5 GO:0036269 swimming behavior(GO:0036269)
0.0 0.5 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 0.1 GO:0043153 entrainment of circadian clock(GO:0009649) entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.2 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.0 0.2 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 1.0 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 7.2 GO:0000398 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 1.7 GO:0006400 tRNA modification(GO:0006400)
0.0 3.0 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 1.8 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 0.5 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 3.0 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.3 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 1.0 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 0.6 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.6 GO:0071897 DNA biosynthetic process(GO:0071897)
0.0 1.6 GO:0006310 DNA recombination(GO:0006310)
0.0 1.1 GO:0031497 chromatin assembly(GO:0031497)
0.0 0.1 GO:0009098 leucine biosynthetic process(GO:0009098)
0.0 0.5 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.3 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.3 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.4 GO:0033014 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0 0.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.3 GO:0048821 erythrocyte development(GO:0048821)
0.0 0.1 GO:0003139 secondary heart field specification(GO:0003139)
0.0 0.2 GO:0035459 cargo loading into vesicle(GO:0035459)
0.0 0.3 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 1.8 GO:0051603 proteolysis involved in cellular protein catabolic process(GO:0051603)
0.0 0.6 GO:0006487 protein N-linked glycosylation(GO:0006487)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.7 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
1.6 4.9 GO:0061689 tricellular tight junction(GO:0061689)
1.4 9.9 GO:0000172 ribonuclease MRP complex(GO:0000172)
1.3 5.3 GO:0034066 RIC1-RGP1 guanyl-nucleotide exchange factor complex(GO:0034066)
1.3 9.2 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
1.3 3.8 GO:0008537 proteasome activator complex(GO:0008537)
1.1 6.4 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
1.1 5.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
1.0 3.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
1.0 3.1 GO:0035339 SPOTS complex(GO:0035339)
0.9 4.3 GO:0008623 CHRAC(GO:0008623)
0.8 6.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.7 2.9 GO:0031262 Ndc80 complex(GO:0031262)
0.7 3.5 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.7 3.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.7 2.7 GO:0070545 PeBoW complex(GO:0070545)
0.6 1.9 GO:0005797 Golgi medial cisterna(GO:0005797)
0.6 1.9 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.6 11.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.6 3.7 GO:0070765 gamma-secretase complex(GO:0070765)
0.6 3.7 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.6 1.7 GO:0033391 chromatoid body(GO:0033391)
0.5 5.9 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.5 2.7 GO:0034518 RNA cap binding complex(GO:0034518)
0.5 3.3 GO:0035101 FACT complex(GO:0035101)
0.4 3.6 GO:0061700 GATOR2 complex(GO:0061700)
0.4 4.0 GO:0032021 NELF complex(GO:0032021)
0.4 22.7 GO:0032432 actin filament bundle(GO:0032432)
0.4 1.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.4 2.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.4 10.4 GO:0000421 autophagosome membrane(GO:0000421)
0.4 8.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.3 1.0 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.3 2.4 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.3 11.6 GO:0005811 lipid particle(GO:0005811)
0.3 1.6 GO:0000811 GINS complex(GO:0000811)
0.3 0.9 GO:0030892 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.3 0.9 GO:0030914 STAGA complex(GO:0030914)
0.3 2.0 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.3 1.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.3 3.8 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.3 0.8 GO:1990077 primosome complex(GO:1990077)
0.3 8.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.3 2.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.3 1.3 GO:0035517 PR-DUB complex(GO:0035517)
0.2 1.4 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.2 0.9 GO:0070724 BMP receptor complex(GO:0070724)
0.2 2.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 17.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 1.6 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 1.1 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2 0.4 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.2 1.9 GO:0071797 LUBAC complex(GO:0071797)
0.2 1.9 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.2 2.3 GO:0000813 ESCRT I complex(GO:0000813)
0.2 1.1 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.2 3.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.2 0.9 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.2 3.7 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.2 2.7 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.2 2.2 GO:0061617 MICOS complex(GO:0061617)
0.2 4.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 4.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 4.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 0.6 GO:0017177 glucosidase II complex(GO:0017177)
0.1 3.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.4 GO:0032389 MutLalpha complex(GO:0032389)
0.1 6.3 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 2.5 GO:0043186 P granule(GO:0043186)
0.1 2.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.6 GO:0018444 translation release factor complex(GO:0018444)
0.1 1.0 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.8 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.1 7.8 GO:0000922 spindle pole(GO:0000922)
0.1 1.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.3 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.7 GO:0030125 clathrin vesicle coat(GO:0030125) clathrin-coated vesicle membrane(GO:0030665)
0.1 1.8 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.1 0.7 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.6 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.8 GO:0071141 SMAD protein complex(GO:0071141)
0.1 1.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.3 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.1 1.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 10.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 5.9 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 7.3 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 1.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.5 GO:0072487 MSL complex(GO:0072487)
0.1 1.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.4 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.5 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 0.8 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 2.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.4 GO:0032300 mismatch repair complex(GO:0032300)
0.1 1.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.9 GO:0017119 Golgi transport complex(GO:0017119)
0.1 1.6 GO:0005876 spindle microtubule(GO:0005876)
0.1 2.5 GO:0055037 recycling endosome(GO:0055037)
0.1 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.8 GO:0005869 dynactin complex(GO:0005869)
0.1 1.4 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 2.1 GO:0030426 growth cone(GO:0030426)
0.1 0.3 GO:0001772 immunological synapse(GO:0001772)
0.1 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 7.0 GO:0005681 spliceosomal complex(GO:0005681)
0.1 1.7 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 1.7 GO:0031965 nuclear membrane(GO:0031965)
0.1 0.2 GO:0016589 NURF complex(GO:0016589)
0.1 17.9 GO:0000139 Golgi membrane(GO:0000139)
0.1 1.9 GO:0005657 replication fork(GO:0005657)
0.1 0.2 GO:0071818 BAT3 complex(GO:0071818)
0.1 2.3 GO:0016592 mediator complex(GO:0016592)
0.1 1.4 GO:0030496 midbody(GO:0030496)
0.1 7.3 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 4.8 GO:0019867 mitochondrial outer membrane(GO:0005741) outer membrane(GO:0019867) organelle outer membrane(GO:0031968)
0.1 7.5 GO:0016604 nuclear body(GO:0016604)
0.1 3.7 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.8 GO:0000177 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 1.2 GO:0005844 polysome(GO:0005844)
0.0 0.5 GO:0008278 cohesin complex(GO:0008278)
0.0 0.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.6 GO:0043195 terminal bouton(GO:0043195)
0.0 3.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.4 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 1.7 GO:0043025 neuronal cell body(GO:0043025)
0.0 15.4 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.4 GO:0035060 brahma complex(GO:0035060)
0.0 2.2 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 12.6 GO:0005794 Golgi apparatus(GO:0005794)
0.0 10.2 GO:0031966 mitochondrial envelope(GO:0005740) mitochondrial membrane(GO:0031966)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0016234 inclusion body(GO:0016234)
0.0 1.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.8 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.6 GO:0030686 90S preribosome(GO:0030686)
0.0 0.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 0.3 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 2.1 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.9 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891) calcium channel complex(GO:0034704)
0.0 0.2 GO:0070993 eukaryotic 43S preinitiation complex(GO:0016282) translation preinitiation complex(GO:0070993)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 12.0 GO:0052657 guanine phosphoribosyltransferase activity(GO:0052657)
1.5 10.8 GO:0097001 sphingolipid binding(GO:0046625) ceramide binding(GO:0097001)
1.5 7.7 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
1.5 5.8 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
1.3 5.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
1.2 7.4 GO:0070698 type I activin receptor binding(GO:0070698)
1.2 3.6 GO:0017125 deoxycytidyl transferase activity(GO:0017125)
1.1 13.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
1.1 4.2 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
1.0 8.0 GO:0004594 pantothenate kinase activity(GO:0004594)
1.0 18.5 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.9 5.6 GO:0034338 short-chain carboxylesterase activity(GO:0034338)
0.9 3.7 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.9 12.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.8 8.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.8 6.4 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.8 2.4 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.8 2.3 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.8 3.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.7 4.3 GO:0090624 endoribonuclease activity, cleaving miRNA-paired mRNA(GO:0090624)
0.7 2.9 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.6 23.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.6 2.3 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.6 3.9 GO:0043495 protein anchor(GO:0043495)
0.5 2.2 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.5 7.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.5 7.3 GO:2001069 glycogen binding(GO:2001069)
0.5 2.6 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.5 1.5 GO:0004743 pyruvate kinase activity(GO:0004743)
0.5 1.5 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.5 6.8 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.5 2.8 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.5 2.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.5 2.8 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.4 3.6 GO:0070728 leucine binding(GO:0070728)
0.4 2.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.4 1.3 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.4 1.3 GO:0035514 DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
0.4 5.0 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.4 2.9 GO:0004691 AMP-activated protein kinase activity(GO:0004679) cAMP-dependent protein kinase activity(GO:0004691)
0.4 1.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.4 8.6 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.4 2.4 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.4 1.2 GO:0004348 glucosylceramidase activity(GO:0004348)
0.4 13.7 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.4 2.6 GO:0015925 galactosidase activity(GO:0015925)
0.3 5.9 GO:0032190 acrosin binding(GO:0032190)
0.3 2.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.3 2.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.3 2.0 GO:1901611 phosphatidic acid binding(GO:0070300) phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.3 1.3 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.3 1.3 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.3 1.9 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.3 5.3 GO:0017136 histone deacetylase activity(GO:0004407) NAD-dependent histone deacetylase activity(GO:0017136)
0.3 1.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.3 2.6 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.3 9.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.3 1.4 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.3 1.1 GO:0004061 arylformamidase activity(GO:0004061)
0.3 25.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.3 3.7 GO:0019894 kinesin binding(GO:0019894)
0.3 1.0 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.3 1.0 GO:0061650 ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.3 3.4 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.3 0.8 GO:0030623 U5 snRNA binding(GO:0030623)
0.3 8.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 0.7 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.2 1.4 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.2 2.4 GO:0097200 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.2 16.0 GO:0003724 RNA helicase activity(GO:0003724)
0.2 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 0.9 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.2 4.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 9.4 GO:0017069 snRNA binding(GO:0017069)
0.2 1.8 GO:0004322 ferroxidase activity(GO:0004322) ferric iron binding(GO:0008199) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 15.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.2 4.2 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.2 0.9 GO:0004427 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.2 1.7 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.2 3.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 0.6 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 6.1 GO:0043130 ubiquitin binding(GO:0043130)
0.2 0.6 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 0.8 GO:0051978 lysophospholipid transporter activity(GO:0051978)
0.2 2.2 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.2 1.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 1.4 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.2 3.1 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.2 0.8 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.2 8.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.2 1.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 0.6 GO:0035174 histone serine kinase activity(GO:0035174)
0.2 1.1 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 2.4 GO:0005080 protein kinase C binding(GO:0005080)
0.2 13.0 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.2 0.9 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.2 1.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.2 3.6 GO:0015248 sterol transporter activity(GO:0015248)
0.2 0.5 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.2 0.5 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.2 3.7 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 1.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.6 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.1 14.5 GO:0005516 calmodulin binding(GO:0005516)
0.1 2.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.7 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 0.7 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.1 9.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.9 GO:0030291 cAMP-dependent protein kinase inhibitor activity(GO:0004862) protein serine/threonine kinase inhibitor activity(GO:0030291)
0.1 0.5 GO:0004630 phospholipase D activity(GO:0004630)
0.1 0.5 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 1.3 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 1.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 1.9 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.4 GO:0016595 glutamate-cysteine ligase activity(GO:0004357) glutamate binding(GO:0016595)
0.1 1.1 GO:0051429 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.4 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.8 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.3 GO:0015288 porin activity(GO:0015288)
0.1 0.6 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 1.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 2.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.6 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.1 2.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 1.0 GO:0051117 ATPase binding(GO:0051117)
0.1 1.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.3 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.1 1.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.6 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 3.1 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.1 1.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 5.0 GO:0030276 clathrin binding(GO:0030276)
0.1 31.6 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 1.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.6 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 0.8 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 7.2 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 1.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 0.9 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.2 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 1.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.4 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.6 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 6.9 GO:0004386 helicase activity(GO:0004386)
0.1 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.1 2.6 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.1 0.3 GO:0043878 aminobutyraldehyde dehydrogenase activity(GO:0019145) glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.1 3.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 0.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 4.4 GO:0031491 nucleosome binding(GO:0031491)
0.1 0.4 GO:0005123 death receptor binding(GO:0005123)
0.1 0.4 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.5 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 1.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0004044 amidophosphoribosyltransferase activity(GO:0004044)
0.0 0.2 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073) ornithine decarboxylase regulator activity(GO:0042979)
0.0 1.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.7 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.5 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.1 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 0.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 1.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 3.7 GO:0004518 nuclease activity(GO:0004518)
0.0 0.2 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 2.6 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.9 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.6 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 5.0 GO:0003682 chromatin binding(GO:0003682)
0.0 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 1.2 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 0.1 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 4.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 11.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.9 14.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.8 1.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.5 2.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3 3.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.3 11.4 PID AP1 PATHWAY AP-1 transcription factor network
0.3 7.9 PID RHOA PATHWAY RhoA signaling pathway
0.2 11.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.2 0.7 PID S1P S1P3 PATHWAY S1P3 pathway
0.2 2.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.2 9.2 PID P73PATHWAY p73 transcription factor network
0.2 4.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 1.8 PID ENDOTHELIN PATHWAY Endothelins
0.1 4.2 PID PLK1 PATHWAY PLK1 signaling events
0.1 3.8 PID ATM PATHWAY ATM pathway
0.1 3.5 PID SHP2 PATHWAY SHP2 signaling
0.1 1.3 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 1.9 PID BARD1 PATHWAY BARD1 signaling events
0.1 4.5 PID P53 REGULATION PATHWAY p53 pathway
0.1 2.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 1.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 7.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 8.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 1.1 PID MYC PATHWAY C-MYC pathway
0.1 2.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 1.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 3.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 1.1 PID ARF 3PATHWAY Arf1 pathway
0.1 0.6 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 0.5 PID EPO PATHWAY EPO signaling pathway
0.1 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.6 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.9 5.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.8 4.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.8 5.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.8 1.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.7 15.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.5 10.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.5 8.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.4 3.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.4 2.8 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.4 4.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.3 1.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.3 2.0 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.3 2.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.3 3.0 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.3 2.7 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.3 5.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.3 4.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 9.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.2 1.1 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.2 0.7 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.2 1.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.2 6.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.2 0.6 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.2 3.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.2 1.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 0.2 REACTOME INFLUENZA LIFE CYCLE Genes involved in Influenza Life Cycle
0.2 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.2 1.0 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 3.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 0.5 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 1.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.9 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 4.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 7.1 REACTOME RNA POL II PRE TRANSCRIPTION EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.1 3.9 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 1.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 0.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 3.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 5.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 22.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.0 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 0.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 0.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.0 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.1 0.6 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 1.0 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 0.8 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 0.7 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 1.0 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 4.0 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.1 0.8 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 0.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.1 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 2.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 0.8 REACTOME KINESINS Genes involved in Kinesins
0.1 1.1 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 0.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 0.3 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 0.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 3.2 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.6 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.8 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 1.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 4.4 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters