Project

DANIO-CODE

Navigation
Downloads

Results for atf4b

Z-value: 0.96

Motif logo

Transcription factors associated with atf4b

Gene Symbol Gene ID Gene Info
ENSDARG00000038141 activating transcription factor 4b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
atf4bdr10_dc_chr3_+_24067430_24067435-0.862.0e-05Click!

Activity profile of atf4b motif

Sorted Z-values of atf4b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of atf4b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr20_+_37891739 4.62 ENSDART00000022060
activating transcription factor 3
chr20_+_37891795 3.55 ENSDART00000022060
activating transcription factor 3
chr12_+_30673985 2.87 ENSDART00000160422
aldehyde dehydrogenase 18 family, member A1
chr14_-_7437682 2.43 ENSDART00000172215
si:ch211-39i2.2
chr12_+_17032829 2.33 ENSDART00000028003
ankyrin repeat domain 22
chr18_+_17611571 2.23 ENSDART00000151850
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr19_+_43745687 2.22 ENSDART00000102384
sestrin 2
chr19_+_43745546 2.22 ENSDART00000145846
sestrin 2
chr18_+_17611931 2.10 ENSDART00000141465
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr12_+_17032997 2.05 ENSDART00000028003
ankyrin repeat domain 22
chr18_+_17611865 2.01 ENSDART00000141465
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr3_-_40142513 1.96 ENSDART00000018626
pdgfa associated protein 1b
chr19_+_43745515 1.74 ENSDART00000145846
sestrin 2
chr19_-_8893920 1.65 ENSDART00000025385
ceramide synthase 2a
chr21_+_30684976 1.62 ENSDART00000040443
zgc:110224
chr14_+_7585289 1.58 ENSDART00000161307
ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
chr20_+_28367799 1.50 ENSDART00000153319
ENSDART00000103330
ChaC, cation transport regulator homolog 1 (E. coli)
chr3_+_40142679 1.49 ENSDART00000009411
BUD31 homolog (S. cerevisiae)
chr24_+_16838877 1.47 ENSDART00000145520
eukaryotic translation initiation factor 2, subunit 3 gamma
chr5_+_56988663 1.45 ENSDART00000074268
zgc:153929
chr12_+_17032963 1.44 ENSDART00000028003
ankyrin repeat domain 22
chr3_+_15244806 1.44 ENSDART00000133168
ataxin 2-like
chr7_+_71263100 1.39 ENSDART00000100396
protein phosphatase 1, regulatory subunit 15A
chr12_-_46943717 1.34 ENSDART00000084557
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr9_-_48516764 1.34 ENSDART00000012938
phosphoglycerate dehydrogenase
chr23_+_25062826 1.30 ENSDART00000172299
Rho GTPase activating protein 4a
chr7_+_71262845 1.21 ENSDART00000100396
protein phosphatase 1, regulatory subunit 15A
chr9_+_2523927 1.15 ENSDART00000166326
si:ch73-167c12.2
chr3_+_25776714 1.15 ENSDART00000170324
target of myb1 membrane trafficking protein
chr10_-_8839096 1.13 ENSDART00000080763
si:dkey-27b3.2
chr20_-_20711298 1.13 ENSDART00000063492
protein phosphatase, Mg2+/Mn2+ dependent, 1Ab
chr18_+_17611519 1.11 ENSDART00000175258
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr9_+_10728013 1.04 ENSDART00000130065
aspartyl-tRNA synthetase
chr3_+_33308831 1.03 ENSDART00000164322
GTP binding protein 1
chr5_-_34600655 1.02 ENSDART00000164396
FCH domain only 2
chr17_-_42523585 1.01 ENSDART00000154755
protein kinase D3
chr7_+_15781933 1.01 ENSDART00000161669
inner mitochondrial membrane peptidase subunit 1
chr24_+_16838984 1.00 ENSDART00000023833
eukaryotic translation initiation factor 2, subunit 3 gamma
chr12_+_13167278 1.00 ENSDART00000092906
protein phosphatase 1, catalytic subunit, alpha isozyme b
chr3_-_30022268 0.99 ENSDART00000159065
nucleobindin 1
chr21_+_30685020 0.99 ENSDART00000040443
zgc:110224
chr14_-_7585265 0.96

chr18_-_18678313 0.94 ENSDART00000076695
alanyl-tRNA synthetase
chr17_-_42523635 0.93 ENSDART00000154755
protein kinase D3
chr12_+_13167781 0.90 ENSDART00000160664
protein phosphatase 1, catalytic subunit, alpha isozyme b
chr14_+_28132910 0.89 ENSDART00000006489
acyl-CoA synthetase long-chain family member 4a
chr9_-_24407859 0.87 ENSDART00000135356
nucleic acid binding protein 1a
chr14_-_30604897 0.86 ENSDART00000161540
si:zfos-80g12.1
chr10_+_16914003 0.82 ENSDART00000177906
unc-13 homolog B
chr15_+_24802510 0.82 ENSDART00000078024
v-crk avian sarcoma virus CT10 oncogene homolog
chr4_+_16795681 0.79 ENSDART00000134054
si:dkey-13i19.8
chr23_-_26301505 0.77 ENSDART00000162423
ENSDARG00000098968
chr5_-_29551051 0.77 ENSDART00000156048
zinc finger and BTB domain containing 44
chr22_+_25911875 0.76 ENSDART00000157842
DnaJ (Hsp40) homolog, subfamily A, member 3B
chr3_-_40142617 0.76 ENSDART00000018626
pdgfa associated protein 1b
chr18_+_20058174 0.73 ENSDART00000146957
uveal autoantigen with coiled-coil domains and ankyrin repeats a
chr3_-_40142333 0.71 ENSDART00000018626
pdgfa associated protein 1b
chr6_-_4067642 0.71 ENSDART00000162497
trafficking protein, kinesin binding 2
chr4_+_16795573 0.70 ENSDART00000134054
si:dkey-13i19.8
chr23_-_43916621 0.67 ENSDART00000015777
ATP-binding cassette, sub-family E (OABP), member 1
chr12_-_13167362 0.67 ENSDART00000152670
pelota mRNA surveillance and ribosome rescue factor
chr4_+_16795523 0.66 ENSDART00000134054
si:dkey-13i19.8
chr12_-_48391342 0.66 ENSDART00000153209
DnaJ (Hsp40) homolog, subfamily B, member 12b
chr8_-_31375316 0.65 ENSDART00000159878
ENSDART00000164134
cAMP responsive element binding protein 3-like 3 like
chr19_+_31297635 0.65 ENSDART00000139599
tyrosyl-tRNA synthetase
chr6_+_49552893 0.63 ENSDART00000022581
RAB22A, member RAS oncogene family
chr9_-_48516909 0.63 ENSDART00000012938
phosphoglycerate dehydrogenase
chr14_+_7585533 0.63 ENSDART00000161307
ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
chr14_-_23504183 0.63 ENSDART00000054264
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr14_-_7000549 0.62 ENSDART00000158914
si:ch211-51f19.1
chr5_-_68751287 0.61 ENSDART00000112692
ENSDARG00000077155
chr23_+_43916520 0.59 ENSDART00000149266
ENSDART00000149503
anaphase promoting complex subunit 10
chr8_+_42910733 0.59 ENSDART00000021715
solute carrier family 23 (ascorbic acid transporter), member 2
chr20_-_20711525 0.58 ENSDART00000063492
protein phosphatase, Mg2+/Mn2+ dependent, 1Ab
chr8_+_22305999 0.57 ENSDART00000075129
leucine rich repeat containing 47
chr3_-_30022354 0.56 ENSDART00000077089
nucleobindin 1
chr23_-_29467861 0.53 ENSDART00000017728
phosphogluconate dehydrogenase
chr16_-_42866318 0.49 ENSDART00000176570
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr6_+_23709605 0.46 ENSDART00000166921
glutamate-ammonia ligase (glutamine synthase) b
chr23_+_43916552 0.46 ENSDART00000149266
ENSDART00000149503
anaphase promoting complex subunit 10
chr23_+_38313746 0.44 ENSDART00000129593
zinc finger protein 217
chr16_-_42866236 0.42 ENSDART00000112879
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr20_-_19632944 0.42 ENSDART00000125830
eukaryotic translation initiation factor 2B, subunit 4 delta
chr8_+_7739964 0.40 ENSDART00000171325
transcription factor binding to IGHM enhancer 3a
chr7_+_28814408 0.40 ENSDART00000173960
ACD, shelterin complex subunit and telomerase recruitment factor
chr14_+_28860508 0.38 ENSDART00000166608
ENSDARG00000037122
chr11_-_23826046 0.38

chr12_+_34851952 0.37 ENSDART00000123988
QKI, KH domain containing, RNA binding 2
chr4_+_25618251 0.36 ENSDART00000044739
ENSDART00000028297
acyl-CoA thioesterase 15
acyl-CoA thioesterase 14
chr15_+_24802607 0.34 ENSDART00000078024
v-crk avian sarcoma virus CT10 oncogene homolog
chr11_+_44909949 0.29 ENSDART00000173116
ENSDART00000167011
ENSDART00000167226
pyrroline-5-carboxylate reductase 1b
chr21_+_9904707 0.28 ENSDART00000171579
hect domain and RLD 7
chr15_-_7340623 0.28 ENSDART00000161613
solute carrier family 7 member 1
chr24_-_38757086 0.27 ENSDART00000170194
solute carrier family 6, member 16b
chr16_-_13927947 0.26 ENSDART00000144856
leukocyte receptor cluster (LRC) member 9
chr13_-_8968136 0.25 ENSDART00000144714
HtrA serine peptidase 2
chr20_+_28901045 0.24 ENSDART00000153046
farnesyltransferase, CAAX box, beta
chr24_+_32610480 0.24 ENSDART00000132417
YME1-like 1a
chr16_-_13927684 0.23 ENSDART00000146719
leukocyte receptor cluster (LRC) member 9
chr15_+_24802238 0.21 ENSDART00000078024
v-crk avian sarcoma virus CT10 oncogene homolog
chr15_+_24802704 0.19 ENSDART00000078024
v-crk avian sarcoma virus CT10 oncogene homolog
chr9_-_48516792 0.19 ENSDART00000012938
phosphoglycerate dehydrogenase
chr8_+_7740024 0.18 ENSDART00000171325
transcription factor binding to IGHM enhancer 3a
chr5_-_34600498 0.18 ENSDART00000164396
FCH domain only 2
chr21_+_3733019 0.12 ENSDART00000170653
dolichyldiphosphatase 1
chr6_-_9471808 0.11 ENSDART00000039280
frizzled class receptor 7b
chr2_+_35258438 0.10 ENSDART00000015827
tenascin R (restrictin, janusin)
chr14_-_23503974 0.08 ENSDART00000054264
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr7_+_71262935 0.08 ENSDART00000100396
protein phosphatase 1, regulatory subunit 15A
chr15_+_20607816 0.06 ENSDART00000169941
small G protein signaling modulator 2
chr3_-_15739926 0.06 ENSDART00000148363
cramped chromatin regulator homolog 1
chr5_-_68727127 0.05 ENSDART00000023983
phosphoserine aminotransferase 1
chr25_-_5921772 0.05 ENSDART00000075184
sorting nexin 1a
chr17_+_8018808 0.04 ENSDART00000131200
myc target 1b
chr6_-_58921392 0.03

chr14_+_37203442 0.03

chr25_+_28450465 0.03 ENSDART00000075151
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr13_-_8968218 0.03 ENSDART00000144142
ENSDART00000144714
HtrA serine peptidase 2
chr5_+_43365528 0.02 ENSDART00000113502
si:dkey-84j12.1
chr23_-_43916434 0.01 ENSDART00000015777
ATP-binding cassette, sub-family E (OABP), member 1
chr3_+_33309011 0.01 ENSDART00000164322
GTP binding protein 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.5 GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902235) negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.9 7.0 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.6 2.2 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.5 2.7 GO:0010922 positive regulation of phosphatase activity(GO:0010922) positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.4 2.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.4 2.6 GO:0000012 single strand break repair(GO:0000012)
0.4 1.5 GO:0006751 glutathione catabolic process(GO:0006751)
0.4 1.8 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.3 1.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.3 1.0 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.2 0.7 GO:0071387 response to cortisol(GO:0051414) cellular response to cortisol stimulus(GO:0071387)
0.2 0.9 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.2 8.2 GO:0009615 response to virus(GO:0009615)
0.1 0.6 GO:0019852 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.1 0.6 GO:0032790 ribosome disassembly(GO:0032790)
0.1 1.7 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 1.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.4 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 0.7 GO:0048311 mitochondrion distribution(GO:0048311)
0.1 0.5 GO:0009084 glutamine family amino acid biosynthetic process(GO:0009084)
0.1 0.9 GO:0015701 bicarbonate transport(GO:0015701)
0.1 2.0 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 1.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.9 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.1 0.5 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.1 1.6 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.7 GO:0006415 translational termination(GO:0006415)
0.0 0.2 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 1.6 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 1.6 GO:0005977 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) energy reserve metabolic process(GO:0006112) glucan metabolic process(GO:0044042)
0.0 0.7 GO:0071218 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.0 0.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.8 GO:0009408 response to heat(GO:0009408)
0.0 1.3 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.6 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.0 GO:0034498 early endosome to Golgi transport(GO:0034498)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.0 GO:0061700 GATOR2 complex(GO:0061700)
0.4 2.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.9 GO:0070876 SOSS complex(GO:0070876)
0.1 2.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.4 GO:0070187 telosome(GO:0070187)
0.0 1.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.7 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.9 GO:0005811 lipid particle(GO:0005811)
0.0 10.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.9 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.3 GO:0005769 early endosome(GO:0005769)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.0 GO:0070728 leucine binding(GO:0070728)
0.7 2.2 GO:0004617 phosphoglycerate dehydrogenase activity(GO:0004617)
0.3 7.5 GO:0044325 ion channel binding(GO:0044325)
0.3 1.0 GO:0004427 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.1 1.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.9 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 2.9 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.1 0.9 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 1.5 GO:0005112 Notch binding(GO:0005112)
0.1 0.7 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.7 GO:0000049 tRNA binding(GO:0000049)
0.0 0.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 2.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 3.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 2.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.8 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.8 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.5 GO:0050661 NADP binding(GO:0050661)
0.0 0.9 GO:0003697 single-stranded DNA binding(GO:0003697)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.9 PID AP1 PATHWAY AP-1 transcription factor network
0.2 1.6 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 2.7 PID BMP PATHWAY BMP receptor signaling
0.0 2.0 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.2 PID CMYB PATHWAY C-MYB transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 0.8 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.4 13.9 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.3 3.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 1.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 2.0 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 2.7 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 2.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends