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Results for atf5a+atf5b

Z-value: 2.10

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Transcription factors associated with atf5a+atf5b

Gene Symbol Gene ID Gene Info
atf5a
ENSDARG00000068096 activating transcription factor 5a
atf5b
ENSDARG00000077785 activating transcription factor 5b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
atf5bdr10_dc_chr15_-_17933972_179340750.947.0e-08Click!
atf5adr10_dc_chr5_-_29818325_29818328-0.741.1e-03Click!

Activity profile of atf5a+atf5b motif

Sorted Z-values of atf5a+atf5b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of atf5a+atf5b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_-_5048203 5.95 ENSDART00000150863
ENSDART00000163417
nrp2a
neuropilin 2a
chr22_-_13139894 5.60 ENSDART00000105762
ahr2
aryl hydrocarbon receptor 2
chr11_-_29410649 5.50 ENSDART00000125753
rpl22
ribosomal protein L22
chr16_-_24602919 5.47 ENSDART00000147478
cadm4
cell adhesion molecule 4
chr3_-_48865474 5.43 ENSDART00000133036
elavl3
ELAV like neuron-specific RNA binding protein 3
chr9_+_25964943 5.21 ENSDART00000147229
ENSDART00000127834
zeb2a
zinc finger E-box binding homeobox 2a
chr11_+_5929544 5.12 ENSDART00000104364
rps15
ribosomal protein S15
chr16_-_24220413 4.79 ENSDART00000103176
bcam
basal cell adhesion molecule (Lutheran blood group)
chr7_+_35769973 4.71 ENSDART00000168658
irx3a
iroquois homeobox 3a
chr7_+_60054116 4.69 ENSDART00000145201
ppp1r14bb
protein phosphatase 1, regulatory (inhibitor) subunit 14Bb
chr3_+_36146072 4.66 ENSDART00000148444
zgc:86896
zgc:86896
chr24_+_9231693 4.62 ENSDART00000082422
si:ch211-285f17.1
si:ch211-285f17.1
chr13_+_23065500 4.48 ENSDART00000158370
sorbs1
sorbin and SH3 domain containing 1
chr20_-_19646761 4.46

chr5_+_37053530 4.38 ENSDART00000161051
sptbn2
spectrin, beta, non-erythrocytic 2
chr5_+_38487183 4.17 ENSDART00000164065
anxa3a
annexin A3a
chr7_-_37816600 4.03 ENSDART00000052366
cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr4_+_7668939 3.95 ENSDART00000149218
elk3
ELK3, ETS-domain protein
chr7_+_25052543 3.90 ENSDART00000110347
cyp26b1
cytochrome P450, family 26, subfamily b, polypeptide 1
chr25_-_32344881 3.78 ENSDART00000012862
isl2a
ISL LIM homeobox 2a
chr4_-_28346021 3.64 ENSDART00000178149
celsr1a
cadherin EGF LAG seven-pass G-type receptor 1a
chr20_-_26521700 3.60 ENSDART00000110883
akap12b
A kinase (PRKA) anchor protein 12b
chr13_-_22877318 3.58 ENSDART00000057638
ENSDART00000171778
hk1
hexokinase 1
chr15_+_37204488 3.52 ENSDART00000157762
aplp1
amyloid beta (A4) precursor-like protein 1
chr11_-_23151247 3.49

chr5_-_2468736 3.47 ENSDART00000170112
rabepk
Rab9 effector protein with kelch motifs
chr18_-_23889256 3.42 ENSDART00000059976
nr2f2
nuclear receptor subfamily 2, group F, member 2
chr2_+_30932612 3.37 ENSDART00000132450
ENSDART00000137012
myom1a
myomesin 1a (skelemin)
chr20_+_30894667 3.31 ENSDART00000145066
nhsl1b
NHS-like 1b
chr14_+_13919450 3.30 ENSDART00000174760
nlgn3a
neuroligin 3a
chr17_+_38528709 3.18 ENSDART00000123298
stard9
StAR-related lipid transfer (START) domain containing 9
chr5_-_47656197 3.08

chr5_-_67233396 3.08 ENSDART00000051833
ENSDART00000124890
gsx1
GS homeobox 1
chr8_+_22268070 2.97 ENSDART00000075126
b3gnt7l
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7, like
chr10_-_7427767 2.88 ENSDART00000167963
ENSDART00000162021
nrg1
neuregulin 1
chr19_+_20209561 2.87 ENSDART00000168833
CR382300.1
ENSDARG00000098798
chr1_+_40795366 2.84 ENSDART00000146310
dtx4
deltex 4, E3 ubiquitin ligase
chr9_+_25964868 2.82 ENSDART00000147229
ENSDART00000127834
zeb2a
zinc finger E-box binding homeobox 2a
chr12_-_3742062 2.77 ENSDART00000092983
ENSDARG00000063555
ENSDARG00000063555
chr14_+_5078937 2.74 ENSDART00000031508
lbx2
ladybird homeobox 2
chr5_-_1698166 2.70 ENSDART00000073462
rplp0
ribosomal protein, large, P0
chr22_+_36687668 2.66 ENSDART00000134031
b3gnt7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr16_-_16796313 2.65

chr3_+_13692658 2.65 ENSDART00000162317
ilf3b
interleukin enhancer binding factor 3b
chr7_+_60054196 2.62 ENSDART00000039827
ppp1r14bb
protein phosphatase 1, regulatory (inhibitor) subunit 14Bb
chr23_-_34970838 2.61 ENSDART00000087219
ENSDARG00000061272
ENSDARG00000061272
chr24_-_16993914 2.60

chr3_+_23573114 2.54 ENSDART00000024256
hoxb6a
homeobox B6a
chr13_+_30743690 2.51 ENSDART00000134809
ercc6
excision repair cross-complementation group 6
chr12_-_47699958 2.48 ENSDART00000171932
ENSDART00000168165
ENSDART00000161985
HHEX
hematopoietically expressed homeobox
chr5_+_18740715 2.46 ENSDART00000089173
atp8b5a
ATPase, class I, type 8B, member 5a
chr9_-_35260503 2.46 ENSDART00000125536
appb
amyloid beta (A4) precursor protein b
chr17_-_37107310 2.44 ENSDART00000151921
dnmt3ab
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr16_+_17705704 2.36

chr15_-_27431216 2.33 ENSDART00000155933
AL954322.2
ENSDARG00000097072
chr10_+_4874841 2.30 ENSDART00000165942
palm2
paralemmin 2
chr16_+_10531986 2.28 ENSDART00000161568
ino80e
INO80 complex subunit E
chr23_-_28390747 2.24

chr5_-_63531729 2.23 ENSDART00000171711
gpsm1a
G protein signaling modulator 1a
chr10_-_7827244 2.21 ENSDART00000111058
mpx
myeloid-specific peroxidase
chr3_+_28450576 2.19 ENSDART00000150893
sept12
septin 12
chr18_-_19467100 2.16 ENSDART00000060363
rpl4
ribosomal protein L4
chr3_+_37565550 2.15 ENSDART00000151236
map3k14a
mitogen-activated protein kinase kinase kinase 14a
chr18_-_23888988 2.15 ENSDART00000059976
nr2f2
nuclear receptor subfamily 2, group F, member 2
chr13_+_30097568 2.13 ENSDART00000134691
rps24
ribosomal protein S24
chr8_-_37011436 2.10 ENSDART00000139567
renbp
renin binding protein
chr24_+_9231768 2.10 ENSDART00000082422
si:ch211-285f17.1
si:ch211-285f17.1
chr18_-_23889025 2.08 ENSDART00000059976
nr2f2
nuclear receptor subfamily 2, group F, member 2
chr6_+_28303542 2.07 ENSDART00000136898
lpp
LIM domain containing preferred translocation partner in lipoma
chr3_-_16077831 2.07 ENSDART00000111707
cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr12_-_3741925 2.07 ENSDART00000092983
ENSDARG00000063555
ENSDARG00000063555
chr15_-_19314712 2.03 ENSDART00000092705
igsf9ba
immunoglobulin superfamily, member 9Ba
chr18_-_50156084 2.00 ENSDART00000006078
loxl1
lysyl oxidase-like 1
chr4_-_16344954 1.97 ENSDART00000079523
epyc
epiphycan
chr22_-_28840467 1.95

chr12_-_7902815 1.95 ENSDART00000088100
ank3b
ankyrin 3b
chr10_+_35344246 1.93 ENSDART00000139229
pora
P450 (cytochrome) oxidoreductase a
chr20_+_6640497 1.91 ENSDART00000138361
tns3.2
tensin 3, tandem duplicate 2
chr23_-_30114528 1.85 ENSDART00000131209
ccdc187
coiled-coil domain containing 187
chr7_+_25052687 1.82 ENSDART00000110347
cyp26b1
cytochrome P450, family 26, subfamily b, polypeptide 1
chr12_+_20578266 1.80 ENSDART00000016099
ENSDARG00000043818
ENSDARG00000043818
chr24_+_24924379 1.79 ENSDART00000115165
amer2
APC membrane recruitment protein 2
chr21_-_26655339 1.79 ENSDART00000149702
ENSDART00000149840
bscl2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr16_+_10531926 1.74 ENSDART00000161568
ino80e
INO80 complex subunit E
chr7_-_13118705 1.71 ENSDART00000081212
polr2l
polymerase (RNA) II (DNA directed) polypeptide L
chr6_-_34024063 1.66 ENSDART00000003701
tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr18_+_22804322 1.64 ENSDART00000149685
gnao1a
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a
chr19_+_30212276 1.62

chr18_-_23889169 1.62 ENSDART00000059976
nr2f2
nuclear receptor subfamily 2, group F, member 2
chr14_-_46649324 1.58

chr22_+_1568413 1.53 ENSDART00000175704
si:ch211-255f4.11
si:ch211-255f4.11
chr24_+_40292617 1.53

chr3_-_48865399 1.50 ENSDART00000028610
elavl3
ELAV like neuron-specific RNA binding protein 3
chr18_+_17564926 1.48

chr11_+_26238579 1.47 ENSDART00000165097
unm_sa1614
un-named sa1614
chr21_-_22078508 1.46 ENSDART00000122389
elmod1
ELMO/CED-12 domain containing 1
chr4_+_7668691 1.46 ENSDART00000149218
elk3
ELK3, ETS-domain protein
chr1_+_31788994 1.43 ENSDART00000152580
nlgn4a
neuroligin 4a
chr17_-_37266525 1.41 ENSDART00000128715
kif3cb
kinesin family member 3Cb
chr16_-_6318609 1.39

chr8_-_50299273 1.38 ENSDART00000023639
nkx2.7
NK2 transcription factor related 7
chr1_+_46537333 1.37

chr8_+_22559432 1.34

chr7_-_29956705 1.29 ENSDART00000173514
znf710b
zinc finger protein 710b
chr20_-_31524559 1.29 ENSDART00000007735
ust
uronyl-2-sulfotransferase
chr11_+_18020191 1.25 ENSDART00000125984
mustn1b
musculoskeletal, embryonic nuclear protein 1b
chr14_-_46649039 1.24

chr1_-_42078442 1.23 ENSDART00000074618
lrrtm1
leucine rich repeat transmembrane neuronal 1
chr18_+_22228682 1.21 ENSDART00000165464
fam65a
family with sequence similarity 65, member A
chr13_-_5423165 1.20

chr4_-_16344835 1.19 ENSDART00000134449
epyc
epiphycan
chr16_+_17706003 1.19

chr3_+_26015378 1.17

chr5_-_25586926 1.17 ENSDART00000137027
ccdc125
coiled-coil domain containing 125
chr1_+_23093475 1.15

chr19_-_11161797 1.15

chr14_-_46649231 1.14

chr19_-_36009321 1.12 ENSDART00000136811
col8a2
collagen, type VIII, alpha 2
chr5_-_25586964 1.11 ENSDART00000163601
ccdc125
coiled-coil domain containing 125
chr10_-_20524670 1.09

chr15_-_40115930 1.06 ENSDART00000157388
lypc
ly6 domain containing, pigment cell
chr9_-_33975936 1.06 ENSDART00000140779
fundc1
FUN14 domain containing 1
chr12_-_3742020 1.04 ENSDART00000092983
ENSDARG00000063555
ENSDARG00000063555
chr2_-_59013059 1.03

chr24_-_20176227 1.02 ENSDART00000163683
map3k20
mitogen-activated protein kinase kinase kinase 20
chr16_-_29599005 1.01

chr20_+_44684239 0.99 ENSDART00000149775
atad2b
ATPase family, AAA domain containing 2B
chr17_-_21773194 0.98 ENSDART00000160296
hmx3a
H6 family homeobox 3a
chr5_-_64637049 0.94 ENSDART00000164649
col27a1b
collagen, type XXVII, alpha 1b
chr23_+_36648211 0.93

chr17_-_20830287 0.93 ENSDART00000149630
ank3a
ankyrin 3a
chr8_-_17692185 0.92

chr18_+_17796754 0.90

chr9_+_30909382 0.87 ENSDART00000146115
klf12b
Kruppel-like factor 12b
chr9_+_30909291 0.84 ENSDART00000146115
klf12b
Kruppel-like factor 12b
chr16_+_11027394 0.80 ENSDART00000172949
pou2f2a
POU class 2 homeobox 2a
chr3_-_32834113 0.77 ENSDART00000125012
casp6
caspase 6, apoptosis-related cysteine peptidase
chr7_+_35770134 0.74 ENSDART00000168658
irx3a
iroquois homeobox 3a
chr18_+_29010470 0.66 ENSDART00000018685
syt9a
synaptotagmin IXa
chr10_-_20524586 0.65

chr11_+_16018035 0.63 ENSDART00000081054
tada3l
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr9_+_6609374 0.60 ENSDART00000122279
fhl2a
four and a half LIM domains 2a
chr15_+_42548643 0.58

chr13_-_34926382 0.58 ENSDART00000178470
btbd3b
BTB (POZ) domain containing 3b
chr17_-_29885237 0.57 ENSDART00000009104
esrrga
estrogen-related receptor gamma a
chr12_+_29140448 0.55

chr7_+_39353697 0.55 ENSDART00000173847
ENSDART00000173845
ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr14_+_26424717 0.54

chr11_-_25086785 0.50 ENSDART00000158598
si:ch211-232b12.5
si:ch211-232b12.5
chr7_+_39181175 0.49

chr19_+_5054263 0.43

chr24_+_34720673 0.41 ENSDART00000105477
lrrtm2
leucine rich repeat transmembrane neuronal 2
chr13_-_44708149 0.41

chr10_+_4874800 0.41 ENSDART00000165942
palm2
paralemmin 2
chr8_-_23239664 0.40

chr20_-_31524614 0.40 ENSDART00000007735
ust
uronyl-2-sulfotransferase
chr10_-_45134642 0.40 ENSDART00000166528
purbb
purine-rich element binding protein Bb
chr20_-_26517630 0.36

chr5_+_63716392 0.30 ENSDART00000015940
edf1
endothelial differentiation-related factor 1
chr12_+_18622682 0.29 ENSDART00000153456
mkl1b
megakaryoblastic leukemia (translocation) 1b
chr20_+_27341026 0.25 ENSDART00000123950
ENSDARG00000077377
ENSDARG00000077377
chr4_-_70948610 0.24 ENSDART00000174299
CABZ01054394.2
ENSDARG00000098324
chr8_+_22268039 0.23 ENSDART00000075126
b3gnt7l
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7, like
chr19_-_5142538 0.23 ENSDART00000130062
chd4a
chromodomain helicase DNA binding protein 4a
chr4_-_13256905 0.23 ENSDART00000026593
ENSDART00000150577
grip1
glutamate receptor interacting protein 1
chr5_-_3077874 0.20

chr3_+_19186724 0.18 ENSDART00000110548
kri1
KRI1 homolog
chr10_-_20524860 0.15

chr8_-_16614882 0.12 ENSDART00000135319
osbpl9
oxysterol binding protein-like 9
chr13_-_743751 0.12 ENSDART00000167256
ENSDARG00000102651
ENSDARG00000102651
chr15_-_8786861 0.12 ENSDART00000154171
arhgap35a
Rho GTPase activating protein 35a
chr3_+_23573053 0.10 ENSDART00000024256
hoxb6a
homeobox B6a
chr3_-_26211047 0.10 ENSDART00000087196
zgc:153240
zgc:153240

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.7 GO:0060363 cranial suture morphogenesis(GO:0060363)
1.9 9.3 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) venous endothelial cell differentiation(GO:0060843) venous endothelial cell fate commitment(GO:0060845)
1.4 5.6 GO:0022602 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698)
1.3 8.0 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
1.1 3.3 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
1.0 2.9 GO:0021755 glial cell migration(GO:0008347) eurydendroid cell differentiation(GO:0021755)
0.9 2.7 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.9 5.5 GO:0003232 bulbus arteriosus development(GO:0003232)
0.8 3.8 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.7 5.5 GO:0071594 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.4 5.9 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.4 4.0 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.4 2.5 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.3 2.0 GO:0018057 peptidyl-lysine oxidation(GO:0018057) protein oxidation(GO:0018158)
0.3 3.6 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.3 6.0 GO:0038084 vascular endothelial growth factor signaling pathway(GO:0038084)
0.3 1.3 GO:0035988 chondrocyte proliferation(GO:0035988)
0.2 3.3 GO:0097475 motor neuron migration(GO:0097475)
0.2 2.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 1.4 GO:0003207 cardiac chamber formation(GO:0003207)
0.2 4.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 2.5 GO:0045332 phospholipid translocation(GO:0045332)
0.2 0.9 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 2.2 GO:2000377 regulation of reactive oxygen species metabolic process(GO:2000377)
0.2 1.7 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.2 2.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 2.1 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 4.4 GO:0051693 regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835) actin filament capping(GO:0051693)
0.1 4.7 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 2.1 GO:0060030 dorsal convergence(GO:0060030)
0.1 1.1 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 1.8 GO:0007398 ectoderm development(GO:0007398)
0.1 1.7 GO:0098781 ncRNA transcription(GO:0098781)
0.1 2.6 GO:0051607 defense response to virus(GO:0051607)
0.1 5.4 GO:0031018 endocrine pancreas development(GO:0031018)
0.1 2.4 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.1 6.6 GO:0045087 innate immune response(GO:0045087)
0.1 0.9 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.6 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 3.6 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.2 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 2.5 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.2 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.5 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 3.4 GO:0006936 muscle contraction(GO:0006936)
0.0 2.1 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 4.0 GO:0006338 chromatin remodeling(GO:0006338)
0.0 2.2 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 1.1 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 2.9 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 6.9 GO:0050767 regulation of neurogenesis(GO:0050767)
0.0 1.0 GO:0048916 posterior lateral line development(GO:0048916)
0.0 1.1 GO:0007623 circadian rhythm(GO:0007623)
0.0 3.0 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.6 GO:0071599 otic vesicle development(GO:0071599)
0.0 1.9 GO:0009725 response to hormone(GO:0009725)
0.0 1.1 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.4 GO:0008091 spectrin(GO:0008091)
0.3 3.4 GO:0031430 M band(GO:0031430)
0.3 5.6 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.2 4.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.2 4.0 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 0.9 GO:0030315 T-tubule(GO:0030315)
0.1 1.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665) DNA-directed RNA polymerase I complex(GO:0005736)
0.1 4.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 2.2 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 4.0 GO:0022626 cytosolic ribosome(GO:0022626) cytosolic small ribosomal subunit(GO:0022627)
0.1 2.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 4.6 GO:0005871 kinesin complex(GO:0005871)
0.1 0.5 GO:0031045 dense core granule(GO:0031045)
0.1 7.6 GO:0005840 ribosome(GO:0005840)
0.0 2.1 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 3.3 GO:0031012 extracellular matrix(GO:0031012)
0.0 6.4 GO:0005615 extracellular space(GO:0005615)
0.0 0.6 GO:0030018 Z disc(GO:0030018)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.7 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.8 9.3 GO:0001972 retinoic acid binding(GO:0001972)
0.7 6.0 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.6 3.6 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.6 2.9 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.5 2.7 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.5 4.2 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.5 6.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.4 5.9 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.4 1.9 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.4 3.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.3 2.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.3 2.6 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 3.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 2.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 2.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 2.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 6.0 GO:0008201 heparin binding(GO:0008201)
0.1 0.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 4.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 6.2 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 13.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 2.2 GO:0004601 peroxidase activity(GO:0004601)
0.0 1.7 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 2.5 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 1.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 2.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 8.0 GO:0051015 actin filament binding(GO:0051015)
0.0 3.6 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 26.7 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 1.7 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 3.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 10.2 GO:0030234 enzyme regulator activity(GO:0030234)
0.0 7.0 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 1.6 GO:0042802 identical protein binding(GO:0042802)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 7.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 3.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 4.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 4.4 PID INSULIN PATHWAY Insulin Pathway
0.0 2.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 2.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 2.9 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.3 5.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 4.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 2.8 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 16.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.2 0.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 2.7 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 9.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 3.6 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 4.2 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1 2.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation