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Results for bach1a+bach2a+bach2b

Z-value: 1.16

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Transcription factors associated with bach1a+bach2a+bach2b

Gene Symbol Gene ID Gene Info
bach2b
ENSDARG00000004074 BTB and CNC homology 1, basic leucine zipper transcription factor 2b
bach2a
ENSDARG00000036569 BTB and CNC homology 1, basic leucine zipper transcription factor 2a
bach1a
ENSDARG00000062553 BTB and CNC homology 1, basic leucine zipper transcription factor 1 a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
bach2bdr10_dc_chr20_-_24223659_24223771-0.968.7e-09Click!
bach2adr10_dc_chr17_+_15666420_156664240.911.1e-06Click!
bach1adr10_dc_chr15_-_8215797_82158030.552.7e-02Click!

Activity profile of bach1a+bach2a+bach2b motif

Sorted Z-values of bach1a+bach2a+bach2b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of bach1a+bach2a+bach2b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_+_45907269 5.55 ENSDART00000132861
cab39l
calcium binding protein 39-like
chr23_+_2786407 4.58 ENSDART00000066086
zgc:114123
zgc:114123
chr6_+_51713264 4.19 ENSDART00000146281
fam65c
family with sequence similarity 65, member C
chr2_+_15432208 4.19 ENSDART00000027171
f3b
coagulation factor IIIb
chr2_+_15432130 3.63 ENSDART00000027171
f3b
coagulation factor IIIb
chr11_+_37371675 3.32 ENSDART00000140502
sh2d5
SH2 domain containing 5
chr5_+_26888744 3.00 ENSDART00000123635
sfrp1a
secreted frizzled-related protein 1a
chr17_+_19606608 2.88 ENSDART00000044993
ENSDART00000131863
rgs7a
regulator of G protein signaling 7a
chr1_+_45907424 2.64 ENSDART00000053240
cab39l
calcium binding protein 39-like
chr22_+_24194444 2.35 ENSDART00000165380
uchl5
ubiquitin carboxyl-terminal hydrolase L5
chr24_-_21224371 2.32 ENSDART00000156537
spice1
spindle and centriole associated protein 1
chr24_-_21224397 2.30 ENSDART00000156537
spice1
spindle and centriole associated protein 1
chr5_-_46028578 2.24

chr5_+_26888419 2.19 ENSDART00000123635
sfrp1a
secreted frizzled-related protein 1a
chr14_+_30433715 2.17 ENSDART00000139552
atl3
atlastin 3
chr9_+_28329384 2.16 ENSDART00000046880
plekhm3
pleckstrin homology domain containing, family M, member 3
chr5_+_35186037 2.08 ENSDART00000127383
ENSDART00000022043
stard8
StAR-related lipid transfer (START) domain containing 8
chr19_-_3547196 2.05 ENSDART00000166107
hivep1
human immunodeficiency virus type I enhancer binding protein 1
chr16_-_24916921 1.94 ENSDART00000153731
si:dkey-79d12.5
si:dkey-79d12.5
chr15_+_25554119 1.88 ENSDART00000162482
zgc:152863
zgc:152863
chr14_+_30434569 1.86 ENSDART00000023054
atl3
atlastin 3
chr11_-_14044356 1.83 ENSDART00000085158
tmem259
transmembrane protein 259
chr2_-_49155324 1.81

chr24_-_21828216 1.80 ENSDART00000030592
acot9.1
acyl-CoA thioesterase 9, tandem duplicate 1
KN150286v1_-_2942 1.80

chr23_-_37010705 1.79 ENSDART00000134461
zgc:193690
zgc:193690
chr15_+_17407036 1.76 ENSDART00000018461
vmp1
vacuole membrane protein 1
chr12_-_27121226 1.71 ENSDART00000153101
psme3
proteasome activator subunit 3
chr19_+_10742944 1.69 ENSDART00000165653
ago3b
argonaute RISC catalytic component 3b
chr8_-_18637047 1.69 ENSDART00000172584
ENSDART00000100516
stap2b
signal transducing adaptor family member 2b
chr5_+_33949469 1.69 ENSDART00000136787
aif1l
allograft inflammatory factor 1-like
chr3_+_48810347 1.68 ENSDART00000133283
prkcsh
protein kinase C substrate 80K-H
chr23_+_25929969 1.64 ENSDART00000145426
hnf4a
hepatocyte nuclear factor 4, alpha
chr23_-_4769182 1.62 ENSDART00000144536
cnbpa
CCHC-type zinc finger, nucleic acid binding protein a
chr5_-_56810425 1.55 ENSDART00000147875
ENSDART00000142776
ENSDARG00000095415
ENSDARG00000095415
chr16_+_46443800 1.55 ENSDART00000131072
rpz2
rapunzel 2
chr8_+_48976657 1.53 ENSDART00000008058
aak1a
AP2 associated kinase 1a
chr1_+_46474561 1.46 ENSDART00000167051
cbr1
carbonyl reductase 1
chr12_-_36113358 1.46

chr10_+_32107014 1.44 ENSDART00000137373
si:ch211-266i6.3
si:ch211-266i6.3
chr22_-_6532901 1.41 ENSDART00000106100
zgc:171490
zgc:171490
chr3_-_29430586 1.40

chr23_-_4769010 1.39 ENSDART00000067293
cnbpa
CCHC-type zinc finger, nucleic acid binding protein a
chr11_-_22210506 1.39 ENSDART00000146873
tmem183a
transmembrane protein 183A
chr7_+_38408691 1.36 ENSDART00000171691
psmc3
proteasome 26S subunit, ATPase 3
chr19_-_44161905 1.34 ENSDART00000058491
ppt1
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
chr7_+_26378093 1.34 ENSDART00000173823
ENSDART00000101053
tp53i11a
tumor protein p53 inducible protein 11a
chr15_-_43954665 1.32 ENSDART00000041249
chordc1a
cysteine and histidine-rich domain (CHORD) containing 1a
chr22_+_31073990 1.32 ENSDART00000111561
zmp:0000000735
zmp:0000000735
chr13_+_40347099 1.30

chr5_+_26888865 1.30 ENSDART00000123635
sfrp1a
secreted frizzled-related protein 1a
chr2_+_48090771 1.30 ENSDART00000135584
ftr19
finTRIM family, member 19
chr3_-_3665840 1.29 ENSDART00000078886
ENSDART00000170539
ENSDARG00000008835
ENSDARG00000008835
chr6_-_19473903 1.27 ENSDART00000126186
psmd12
proteasome 26S subunit, non-ATPase 12
chr19_-_44161951 1.26 ENSDART00000058491
ppt1
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
chr13_+_6908853 1.24 ENSDART00000109434
aifm2
apoptosis-inducing factor, mitochondrion-associated, 2
chr7_-_57055583 1.22

chr11_-_38856849 1.21 ENSDART00000113185
ap5b1
adaptor-related protein complex 5, beta 1 subunit
chr5_+_44204845 1.21 ENSDART00000141198
ctsla
cathepsin La
chr19_+_43277870 1.20 ENSDART00000135164
pdcd6ip
programmed cell death 6 interacting protein
chr24_-_33475705 1.20 ENSDART00000074161
slc4a2b
solute carrier family 4 (anion exchanger), member 2b
chr2_-_8002471 1.19 ENSDART00000146360
tbl1xr1b
transducin (beta)-like 1 X-linked receptor 1b
chr8_-_18637019 1.19 ENSDART00000172584
ENSDART00000100516
stap2b
signal transducing adaptor family member 2b
chr20_-_16949608 1.18 ENSDART00000027582
brms1lb
breast cancer metastasis-suppressor 1-like b
chr23_+_45486958 1.17 ENSDART00000111126
psip1b
PC4 and SFRS1 interacting protein 1b
chr15_+_40340914 1.16 ENSDART00000063779
efhd1
EF-hand domain family, member D1
chr21_-_30217360 1.16 ENSDART00000101054
dnajc18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr12_-_27121343 1.13 ENSDART00000002835
psme3
proteasome activator subunit 3
chr23_+_4315077 1.05 ENSDART00000008761
arl6ip5b
ADP-ribosylation factor-like 6 interacting protein 5b
chr9_-_2522639 1.01 ENSDART00000137706
scrn3
secernin 3
chr21_+_13136338 0.99 ENSDART00000142569
specc1lb
sperm antigen with calponin homology and coiled-coil domains 1-like b
chr20_-_43826667 0.99 ENSDART00000100637
mixl1
Mix paired-like homeobox
chr13_-_2296283 0.99 ENSDART00000017148
gclc
glutamate-cysteine ligase, catalytic subunit
chr6_-_6818607 0.98 ENSDART00000151822
tuba8l4
tubulin, alpha 8 like 4
chr1_-_51863300 0.98 ENSDART00000004233
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr16_-_30561224 0.98 ENSDART00000155436
CR848742.1
ENSDARG00000097142
chr5_+_44204661 0.97 ENSDART00000122288
ctsla
cathepsin La
chr18_+_15873032 0.96 ENSDART00000141800
eea1
early endosome antigen 1
chr2_+_37855019 0.96 ENSDART00000113337
parp2
poly (ADP-ribose) polymerase 2
chr13_-_37523664 0.95 ENSDART00000115354
si:dkey-188i13.10
si:dkey-188i13.10
chr13_-_2296041 0.95 ENSDART00000126697
gclc
glutamate-cysteine ligase, catalytic subunit
chr23_+_17596460 0.95 ENSDART00000002714
slc17a9b
solute carrier family 17 (vesicular nucleotide transporter), member 9b
chr18_+_44856321 0.95 ENSDART00000097328
arfgap2
ADP-ribosylation factor GTPase activating protein 2
chr20_-_16949680 0.93 ENSDART00000027582
brms1lb
breast cancer metastasis-suppressor 1-like b
chr7_+_71262845 0.92 ENSDART00000100396
ppp1r15a
protein phosphatase 1, regulatory subunit 15A
chr14_+_28158771 0.91 ENSDART00000019003
psmd10
proteasome 26S subunit, non-ATPase 10
chr14_+_8641470 0.90 ENSDART00000158025
rps6kal
ribosomal protein S6 kinase a, like
chr24_+_36351542 0.88 ENSDART00000062745
riok3
RIO kinase 3 (yeast)
chr14_+_8641516 0.86 ENSDART00000158025
rps6kal
ribosomal protein S6 kinase a, like
chr3_+_17728616 0.85 ENSDART00000167953
dnajc7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr13_+_7243353 0.85 ENSDART00000146592
gbf1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr19_+_37533306 0.85 ENSDART00000032341
pef1
penta-EF-hand domain containing 1
chr12_-_3042545 0.85 ENSDART00000002867
ENSDART00000126315
rfng
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr18_+_7584201 0.82 ENSDART00000163709
zgc:77650
zgc:77650
chr19_-_42847112 0.81 ENSDART00000086961
vps45
vacuolar protein sorting 45 homolog (S. cerevisiae)
chr7_+_34277682 0.80 ENSDART00000073447
fhod1
formin homology 2 domain containing 1
chr5_-_1102450 0.79 ENSDART00000115044
mbd2
methyl-CpG binding domain protein 2
chr6_+_41455676 0.79 ENSDART00000007798
ENSDART00000162135
twf2a
twinfilin actin-binding protein 2a
chr7_-_29956782 0.78 ENSDART00000173514
znf710b
zinc finger protein 710b
chr5_-_62963536 0.78 ENSDART00000050865
surf4l
surfeit gene 4, like
chr4_-_4526152 0.77 ENSDART00000057519
zgc:194209
zgc:194209
chr8_+_48976994 0.77 ENSDART00000008058
aak1a
AP2 associated kinase 1a
chr4_+_76548332 0.77 ENSDART00000159452
ENSDART00000092415
pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr5_-_41523801 0.75 ENSDART00000051135
emc6
ER membrane protein complex subunit 6
chr5_-_41523490 0.75 ENSDART00000051135
emc6
ER membrane protein complex subunit 6
chr7_+_7463565 0.74 ENSDART00000091099
ino80b
INO80 complex subunit B
chr5_-_32698092 0.73 ENSDART00000015076
zgc:103692
zgc:103692
chr23_-_37010664 0.73 ENSDART00000102886
zgc:193690
zgc:193690
chr4_-_7644310 0.72 ENSDART00000157751
BX649411.1
ENSDARG00000101254
chr2_-_1028487 0.71 ENSDART00000058289
dusp22b
dual specificity phosphatase 22b
chr8_-_49217824 0.70

chr15_-_31296457 0.69 ENSDART00000008854
wsb1
WD repeat and SOCS box containing 1
chr11_-_18649022 0.69

chr15_-_31296524 0.67 ENSDART00000008854
wsb1
WD repeat and SOCS box containing 1
chr12_-_3042573 0.65 ENSDART00000002867
ENSDART00000126315
rfng
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr19_-_37533194 0.64

chr11_-_29689360 0.64 ENSDART00000145251
pir
pirin
chr16_+_27608996 0.64 ENSDART00000147611
si:ch211-197h24.6
si:ch211-197h24.6
chr9_+_22846535 0.64 ENSDART00000101765
si:dkey-189g17.2
si:dkey-189g17.2
chr20_-_26516874 0.63

chr16_+_48772036 0.61 ENSDART00000148709
brd2b
bromodomain containing 2b
chr20_+_49380442 0.61

chr15_+_20961370 0.61 ENSDART00000154854
CR848784.5
ENSDARG00000097996
chr5_+_32698516 0.60 ENSDART00000097945
usp20
ubiquitin specific peptidase 20
chr5_+_44205128 0.60 ENSDART00000136965
ctsla
cathepsin La
chr20_-_16649213 0.60 ENSDART00000137601
ches1
checkpoint suppressor 1
chr19_+_10477101 0.59 ENSDART00000151735
necap1
NECAP endocytosis associated 1
chr13_+_7243325 0.59 ENSDART00000146592
gbf1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr9_-_30560440 0.58 ENSDART00000079068
asb11
ankyrin repeat and SOCS box containing 11
chr17_+_28657998 0.56 ENSDART00000159067
hectd1
HECT domain containing 1
chr6_-_39313358 0.55

chr22_+_39012456 0.55 ENSDART00000176985
CABZ01044615.1
ENSDARG00000108810
chr11_-_29689291 0.54 ENSDART00000145251
pir
pirin
chr8_+_48976926 0.50 ENSDART00000008058
aak1a
AP2 associated kinase 1a
chr7_-_29262814 0.47 ENSDART00000124028
anxa2b
annexin A2b
chr3_-_34687314 0.47 ENSDART00000084448
psmd11a
proteasome 26S subunit, non-ATPase 11a
chr11_+_19208363 0.46 ENSDART00000165906
prickle2b
prickle homolog 2b
chr21_-_30217568 0.45 ENSDART00000101054
dnajc18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr8_-_46904610 0.44

chr13_-_2296317 0.44 ENSDART00000017148
gclc
glutamate-cysteine ligase, catalytic subunit
chr7_-_6273677 0.44 ENSDART00000173419
si:ch73-368j24.1
si:ch73-368j24.1
chr6_+_55250892 0.44

chr21_-_20983956 0.43 ENSDART00000064032
eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
chr19_-_8829701 0.43 ENSDART00000031173
rps27.1
ribosomal protein S27, isoform 1
chr20_-_34167039 0.42 ENSDART00000017941
tprb
translocated promoter region b, nuclear basket protein
chr13_+_21757676 0.42 ENSDART00000162709
ndst2a
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2a
chr6_+_37774863 0.42 ENSDART00000110770
herc2
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr17_-_20675997 0.42 ENSDART00000063613
ENSDART00000171575
ccdc6a
coiled-coil domain containing 6a
chr5_+_41463969 0.42 ENSDART00000035235
UBB
si:ch211-202a12.4
chr21_-_10962154 0.41 ENSDART00000084061
nedd4l
neural precursor cell expressed, developmentally down-regulated 4-like
chr4_-_1952230 0.41 ENSDART00000135749
nudt4b
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr1_+_46474845 0.41 ENSDART00000053152
cbr1
carbonyl reductase 1
chr16_-_13927947 0.40 ENSDART00000144856
leng9
leukocyte receptor cluster (LRC) member 9
chr16_-_13927684 0.40 ENSDART00000146719
leng9
leukocyte receptor cluster (LRC) member 9
chr16_+_17706214 0.39

chr22_+_39098205 0.38 ENSDART00000002826
gmppb
GDP-mannose pyrophosphorylase B
chr3_+_12438915 0.38 ENSDART00000159252
abca3b
ATP-binding cassette, sub-family A (ABC1), member 3b
chr10_+_187740 0.36 ENSDART00000167367
ets2
v-ets avian erythroblastosis virus E26 oncogene homolog 2
chr22_-_6532694 0.32 ENSDART00000106100
zgc:171490
zgc:171490
chr14_-_36422904 0.32 ENSDART00000074786
ctso
cathepsin O
chr14_-_5509554 0.31

chr4_-_7644374 0.31 ENSDART00000157751
BX649411.1
ENSDARG00000101254
chr21_+_10773736 0.31 ENSDART00000137858
alpk2
alpha-kinase 2
chr7_-_29452646 0.31 ENSDART00000112651
vps13c
vacuolar protein sorting 13 homolog C (S. cerevisiae)
chr15_+_17407258 0.30 ENSDART00000111753
vmp1
vacuole membrane protein 1
chr11_+_44805115 0.28 ENSDART00000167828
tmc6b
transmembrane channel-like 6b
KN150359v1_+_69830 0.28

chr17_+_41313762 0.26 ENSDART00000128482
fosl2
fos-like antigen 2
chr16_-_27609082 0.26

chr15_-_43954596 0.25 ENSDART00000041249
chordc1a
cysteine and histidine-rich domain (CHORD) containing 1a
chr14_-_470112 0.25 ENSDART00000115093
zgc:172215
zgc:172215
chr10_-_28474052 0.25

chr21_+_6009262 0.25 ENSDART00000065858
fpgs
folylpolyglutamate synthase
chr11_+_11284030 0.23 ENSDART00000026814
ptp4a1
protein tyrosine phosphatase type IVA, member 1
chr19_+_33506239 0.23 ENSDART00000019459
fam91a1
family with sequence similarity 91, member A1
chr18_+_15872911 0.20 ENSDART00000141800
eea1
early endosome antigen 1
chr12_+_8040369 0.20 ENSDART00000124084
zgc:194508
zgc:194508
chr19_-_10476653 0.19 ENSDART00000109488
zgc:194578
zgc:194578
chr10_-_7019880 0.19 ENSDART00000123312
sh2d4a
SH2 domain containing 4A
chr18_-_15187432 0.18 ENSDART00000111333
mterf2
mitochondrial transcription termination factor 2
chr7_+_71262935 0.18 ENSDART00000100396
ppp1r15a
protein phosphatase 1, regulatory subunit 15A
chr3_+_12438761 0.17 ENSDART00000159252
abca3b
ATP-binding cassette, sub-family A (ABC1), member 3b
chr17_+_51593393 0.17 ENSDART00000004379
nol10
nucleolar protein 10
chr22_+_17278690 0.16 ENSDART00000088460
rabgap1l
RAB GTPase activating protein 1-like
chr7_-_30654776 0.16 ENSDART00000075421
sord
sorbitol dehydrogenase
chr11_+_6450876 0.16 ENSDART00000170180
CU062501.2
ENSDARG00000103967
chr17_+_35149038 0.16 ENSDART00000163557
asap2a
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2a
chr4_+_46414646 0.16 ENSDART00000179615
BX324155.2
ENSDARG00000107359
chr5_-_42350607 0.16 ENSDART00000149868
grsf1
G-rich RNA sequence binding factor 1
chr20_-_43826581 0.14 ENSDART00000100637
mixl1
Mix paired-like homeobox
chr17_-_31027949 0.14 ENSDART00000152016
eml1
echinoderm microtubule associated protein like 1
chr5_-_2540097 0.14

chr1_+_51503405 0.13 ENSDART00000171597
ENSDART00000007079
asna1
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr11_-_269181 0.13

chr13_-_49294664 0.13 ENSDART00000165868
tomm20a
translocase of outer mitochondrial membrane 20
chr21_+_22856217 0.12 ENSDART00000065565
alg8
ALG8, alpha-1,3-glucosyltransferase
chr2_-_37854616 0.12 ENSDART00000171409
mettl17
methyltransferase like 17
chr23_+_24575330 0.12 ENSDART00000078824
szrd1
SUZ RNA binding domain containing 1
chr22_+_39110524 0.11 ENSDART00000153841
lmcd1
LIM and cysteine-rich domains 1
KN150266v1_-_69477 0.10

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.6 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.5 2.8 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.4 2.4 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.4 4.6 GO:0046599 regulation of centriole replication(GO:0046599)
0.3 0.9 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.3 1.2 GO:0030224 monocyte differentiation(GO:0030224)
0.3 0.8 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.3 1.8 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.2 1.0 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.2 3.4 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.2 6.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.2 1.1 GO:0010922 positive regulation of phosphatase activity(GO:0010922) positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.2 2.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.2 2.6 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.2 1.5 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.2 7.8 GO:0007596 blood coagulation(GO:0007596) hemostasis(GO:0007599)
0.2 1.8 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.1 1.5 GO:0035283 fourth ventricle development(GO:0021592) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 2.1 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.4 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 0.8 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.8 GO:0001765 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1 0.6 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 1.7 GO:0097178 ruffle assembly(GO:0097178)
0.1 1.5 GO:0070365 hepatocyte differentiation(GO:0070365)
0.1 2.8 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.1 0.5 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.1 0.8 GO:0006901 vesicle coating(GO:0006901)
0.1 0.8 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 3.5 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 1.7 GO:0072091 regulation of stem cell proliferation(GO:0072091)
0.1 1.2 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.3 GO:2000725 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.1 1.6 GO:0051788 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.1 1.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.4 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.2 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.1 0.3 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 1.7 GO:0006491 N-glycan processing(GO:0006491)
0.1 1.6 GO:0051298 centrosome duplication(GO:0051298)
0.1 3.3 GO:0016575 histone deacetylation(GO:0016575)
0.1 0.6 GO:0021551 central nervous system morphogenesis(GO:0021551) protein K48-linked deubiquitination(GO:0071108)
0.0 1.2 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 2.1 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:1901906 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.4 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.4 GO:0030202 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.6 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 1.9 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 2.2 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.2 GO:0019405 alditol catabolic process(GO:0019405)
0.0 0.6 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 1.8 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 1.1 GO:0001706 endoderm formation(GO:0001706)
0.0 1.0 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 1.0 GO:0051051 negative regulation of transport(GO:0051051)
0.0 0.7 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 2.8 GO:0006955 immune response(GO:0006955)
0.0 0.4 GO:0055088 lipid homeostasis(GO:0055088)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0008537 proteasome activator complex(GO:0008537)
0.5 2.4 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.4 1.7 GO:0017177 glucosidase II complex(GO:0017177)
0.2 1.7 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 2.5 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 1.0 GO:0005921 gap junction(GO:0005921)
0.1 1.7 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 1.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 2.5 GO:0032587 ruffle membrane(GO:0032587)
0.1 2.1 GO:0070822 Sin3-type complex(GO:0070822)
0.1 2.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 4.6 GO:0005814 centriole(GO:0005814)
0.1 0.8 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 0.6 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 3.3 GO:0014069 postsynaptic density(GO:0014069)
0.1 0.9 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 1.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.8 GO:0030665 clathrin vesicle coat(GO:0030125) clathrin-coated vesicle membrane(GO:0030665)
0.0 1.2 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 4.6 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 1.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.5 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.9 GO:0000502 proteasome complex(GO:0000502)
0.0 3.7 GO:0005764 lysosome(GO:0005764)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0016595 glutamate-cysteine ligase activity(GO:0004357) glutamate binding(GO:0016595)
0.6 2.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.4 1.5 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.4 2.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.3 8.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.3 1.7 GO:0090624 endoribonuclease activity, cleaving miRNA-paired mRNA(GO:0090624)
0.3 0.8 GO:0016844 amine-lyase activity(GO:0016843) strictosidine synthase activity(GO:0016844)
0.2 1.0 GO:0016805 dipeptidase activity(GO:0016805)
0.2 2.2 GO:0070628 proteasome binding(GO:0070628)
0.2 0.8 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.2 2.6 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 2.9 GO:0035591 signaling adaptor activity(GO:0035591)
0.1 6.3 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 6.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 1.8 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 1.5 GO:0032977 membrane insertase activity(GO:0032977)
0.1 0.4 GO:0008905 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.1 1.8 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.6 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 1.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 1.2 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 0.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 2.8 GO:0045182 translation regulator activity(GO:0045182)
0.1 0.3 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.2 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326)
0.1 0.5 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.1 2.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.2 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 3.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 2.5 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.2 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.2 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID ARF 3PATHWAY Arf1 pathway
0.0 1.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.1 PID BMP PATHWAY BMP receptor signaling
0.0 0.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 8.2 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.2 1.7 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 2.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 3.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 3.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 2.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 2.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.2 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production