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Results for bcl6aa+bcl6ab+bcl6b

Z-value: 1.26

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Transcription factors associated with bcl6aa+bcl6ab+bcl6b

Gene Symbol Gene ID Gene Info
bcl6ab
ENSDARG00000069295 BCL6A transcription repressor b
bcl6b
ENSDARG00000069335 BCL6B transcription repressor
bcl6aa
ENSDARG00000070864 BCL6A transcription repressor a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
bcl6adr10_dc_chr6_-_28231995_282319990.273.1e-01Click!
bcl6abdr10_dc_chr2_-_10300329_10300384-0.146.1e-01Click!
bcl6bdr10_dc_chr7_+_19765237_19765243-0.097.5e-01Click!

Activity profile of bcl6aa+bcl6ab+bcl6b motif

Sorted Z-values of bcl6aa+bcl6ab+bcl6b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of bcl6aa+bcl6ab+bcl6b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr11_-_17829889 3.26 ENSDART00000018948
ENSDART00000172343
cishb
cytokine inducible SH2-containing protein b
chr16_-_45950530 3.06 ENSDART00000060822
afp4
antifreeze protein type IV
chr7_+_44373815 2.98 ENSDART00000170721
si:dkey-56m19.5
si:dkey-56m19.5
chr11_+_43083105 2.88 ENSDART00000130131
sult6b1
sulfotransferase family, cytosolic, 6b, member 1
chr23_+_42431407 2.61 ENSDART00000169821
cyp2aa8
cytochrome P450, family 2, subfamily AA, polypeptide 8
chr14_-_3264798 1.95 ENSDART00000171601
im:7150988
im:7150988
chr11_-_42934175 1.85 ENSDART00000172929
sptbn1
spectrin, beta, non-erythrocytic 1
chr15_-_40391882 1.70

chr24_-_2830194 1.58 ENSDART00000164913
si:ch211-152c8.5
si:ch211-152c8.5
chr1_-_50147413 1.54 ENSDART00000080389
fam13a
family with sequence similarity 13, member A
chr16_-_14973966 1.49

chr2_+_314278 1.47 ENSDART00000155595
zgc:174263
zgc:174263
chr11_-_22143133 1.43 ENSDART00000159681
tfeb
transcription factor EB
chr17_-_30846176 1.41 ENSDART00000062811
yy1a
YY1 transcription factor a
chr4_-_72097569 1.33 ENSDART00000108669
zgc:171551
zgc:171551
chr21_-_2191847 1.32 ENSDART00000159315
si:dkey-50i6.5
si:dkey-50i6.5
chr11_+_2306187 1.29

chr8_+_32604349 1.26 ENSDART00000126833
hmcn2
hemicentin 2
chr21_+_35181329 1.24 ENSDART00000135256
ubtd2
ubiquitin domain containing 2
chr3_-_60522527 1.22 ENSDART00000166334
srsf2b
serine/arginine-rich splicing factor 2b
chr18_+_22120282 1.21 ENSDART00000147230
zgc:158868
zgc:158868
chr7_-_22519196 1.17 ENSDART00000129919
ENSDARG00000091111
ENSDARG00000091111
chr11_-_8158013 1.14 ENSDART00000024046
uox
urate oxidase
chr15_-_29454583 1.13 ENSDART00000145976
serpinh1b
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr14_-_11765407 1.11 ENSDART00000165581
tmsb1
thymosin beta 1
chr11_-_17829827 1.10 ENSDART00000018948
ENSDART00000172343
cishb
cytokine inducible SH2-containing protein b
chr19_+_30212276 1.07

chr14_-_31128891 1.01

chr1_+_27174549 1.01 ENSDART00000102337
dnajb14
DnaJ (Hsp40) homolog, subfamily B, member 14
chr18_-_36956268 1.00

chr13_-_37482466 0.99 ENSDART00000147934
zgc:123068
zgc:123068
chr3_+_39514598 0.97 ENSDART00000156038
epn2
epsin 2
chr7_+_5408319 0.94 ENSDART00000142709
si:dkeyp-67a8.4
si:dkeyp-67a8.4
chr14_+_11151485 0.93 ENSDART00000169202
si:ch211-153b23.5
si:ch211-153b23.5
chr10_+_5268009 0.93 ENSDART00000114491
ror2
receptor tyrosine kinase-like orphan receptor 2
chr2_-_10919978 0.93 ENSDART00000005944
rpl5a
ribosomal protein L5a
chr23_-_33631518 0.92 ENSDART00000018301
itga5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr5_-_42272455 0.90 ENSDART00000161586
flot2a
flotillin 2a
chr21_-_2212429 0.88 ENSDART00000165754
si:dkey-50i6.6
si:dkey-50i6.6
chr13_+_46637827 0.88 ENSDART00000167931
mtrf1l
mitochondrial translational release factor 1-like
chr1_-_57931565 0.85 ENSDART00000109528
adgre5b.3
adhesion G protein-coupled receptor E5b, duplicate 3
chr2_-_21960233 0.85 ENSDART00000027587
ralab
v-ral simian leukemia viral oncogene homolog Ab (ras related)
chr17_+_1080921 0.83

chr14_+_6122948 0.83 ENSDART00000149783
ENSDART00000148461
abca1b
ATP-binding cassette, sub-family A (ABC1), member 1B
chr20_+_10179249 0.82 ENSDART00000141877
kcnk10a
potassium channel, subfamily K, member 10a
chr7_+_32097831 0.81 ENSDART00000169588
LGR4
leucine rich repeat containing G protein-coupled receptor 4
chr23_-_19789409 0.81 ENSDART00000131860
rpl10
ribosomal protein L10
chr23_+_42449089 0.79 ENSDART00000171119
cyp2aa9
cytochrome P450, family 2, subfamily AA, polypeptide 9
chr1_-_25704525 0.79 ENSDART00000171614
ppa2
pyrophosphatase (inorganic) 2
chr11_-_42933969 0.79 ENSDART00000172929
sptbn1
spectrin, beta, non-erythrocytic 1
chr11_+_43083214 0.77 ENSDART00000130131
sult6b1
sulfotransferase family, cytosolic, 6b, member 1
chr25_+_35791595 0.76 ENSDART00000103013
ENSDARG00000070286
ENSDARG00000070286
chr18_+_22120507 0.76 ENSDART00000147230
zgc:158868
zgc:158868
chr11_-_18649022 0.74

chr1_+_43352429 0.70 ENSDART00000124873
si:ch73-109d9.4
si:ch73-109d9.4
chr24_-_37800277 0.69 ENSDART00000141414
zgc:112185
zgc:112185
chr1_-_20131393 0.69

chr22_-_37676744 0.69 ENSDART00000028085
ttc14
tetratricopeptide repeat domain 14
chr5_+_4033390 0.68 ENSDART00000149185
sat1a.2
spermidine/spermine N1-acetyltransferase 1a, duplicate 2
chr17_-_32471070 0.66

chr25_+_35788501 0.64 ENSDART00000121838
hist1h4l
histone 1, H4, like
chr21_-_26078089 0.63 ENSDART00000139320
nipal4
NIPA-like domain containing 4
chr24_-_33377293 0.63 ENSDART00000124938
si:ch1073-406l10.2
si:ch1073-406l10.2
chr22_-_37676556 0.62 ENSDART00000028085
ttc14
tetratricopeptide repeat domain 14
chr19_+_42936516 0.62 ENSDART00000165747
BX950855.1
ENSDARG00000103815
chr7_-_6289729 0.61 ENSDART00000173323
hist1h4l
histone 1, H4, like
chr10_+_17470158 0.60

chr8_-_23218886 0.60 ENSDART00000131632
ptk6a
PTK6 protein tyrosine kinase 6a
chr20_-_23949621 0.59

chr14_+_11089382 0.57 ENSDART00000106657
glod5
glyoxalase domain containing 5
chr1_-_54331157 0.55 ENSDART00000083572
zgc:136864
zgc:136864
chr25_-_34632441 0.55 ENSDART00000111724
hist1h4l
histone 1, H4, like
chr21_+_35181410 0.53 ENSDART00000135256
ubtd2
ubiquitin domain containing 2
chr23_-_1024735 0.52

chr18_-_46185361 0.49 ENSDART00000021192
kcnk6
potassium channel, subfamily K, member 6
chr23_+_42381296 0.49 ENSDART00000158684
ENSDART00000159985
ENSDART00000172144
cyp2aa11
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr13_+_33578737 0.48 ENSDART00000161465
CABZ01087953.1
ENSDARG00000104106
chr10_+_17470092 0.48

chr19_+_30212487 0.48

chr16_+_17808801 0.47 ENSDART00000149596
si:dkey-87o1.2
si:dkey-87o1.2
chr19_+_30212565 0.47

chr10_+_5267746 0.46 ENSDART00000114491
ror2
receptor tyrosine kinase-like orphan receptor 2
chr7_-_22519593 0.46 ENSDART00000173496
ENSDARG00000091111
ENSDARG00000091111
chr15_-_5811394 0.45 ENSDART00000158522
hnrnpl2
heterogeneous nuclear ribonucleoprotein L2
chr23_+_19743720 0.44 ENSDART00000031872
kctd6b
potassium channel tetramerization domain containing 6b
chr20_+_25669615 0.44 ENSDART00000063107
cyp2p7
cytochrome P450, family 2, subfamily P, polypeptide 7
chr1_-_49028598 0.43

chr5_-_64315770 0.41 ENSDART00000169287
zgc:110283
zgc:110283
chr20_-_25726868 0.41 ENSDART00000126716
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr14_+_6122901 0.40 ENSDART00000149783
ENSDART00000148461
abca1b
ATP-binding cassette, sub-family A (ABC1), member 1B
chr6_-_59510397 0.40 ENSDART00000170685
gli1
GLI family zinc finger 1
chr6_+_37677155 0.39 ENSDART00000122199
ENSDART00000065127
cyfip1
cytoplasmic FMR1 interacting protein 1
chr21_-_41191143 0.39 ENSDART00000164125
crebrf
creb3 regulatory factor
chr2_+_14016329 0.38

chr18_+_18874077 0.37 ENSDART00000091094
pllp
plasmolipin
chr21_+_15660541 0.37 ENSDART00000101956
ENSDART00000026903
ptpra
protein tyrosine phosphatase, receptor type, A
chr18_+_36085169 0.37 ENSDART00000059347
bckdha
branched chain keto acid dehydrogenase E1, alpha polypeptide
chr21_+_15774822 0.37 ENSDART00000122015
fam169ab
family with sequence similarity 169, member Ab
chr4_-_18447913 0.36 ENSDART00000141671
socs2
suppressor of cytokine signaling 2
chr8_-_47156727 0.36

chr14_-_6680528 0.36 ENSDART00000060990
eif4ebp3l
eukaryotic translation initiation factor 4E binding protein 3, like
chr16_+_10438774 0.36 ENSDART00000121966
mdc1
mediator of DNA damage checkpoint 1
chr15_-_5811458 0.35 ENSDART00000158522
hnrnpl2
heterogeneous nuclear ribonucleoprotein L2
chr19_+_28363333 0.35

chr19_+_5501487 0.34 ENSDART00000132874
eif1b
eukaryotic translation initiation factor 1B
chr10_+_5267937 0.34 ENSDART00000114491
ror2
receptor tyrosine kinase-like orphan receptor 2
chr24_+_42884 0.33 ENSDART00000122785
zgc:152808
zgc:152808
chr15_+_23615727 0.33 ENSDART00000152720
MARK4
microtubule affinity regulating kinase 4
chr8_+_47108500 0.32 ENSDART00000142979
arhgef16
Rho guanine nucleotide exchange factor (GEF) 16
chr14_-_5371581 0.32 ENSDART00000012116
tlx2
T-cell leukemia, homeobox 2
chr10_+_17470024 0.32

chr8_+_47108614 0.32 ENSDART00000142979
arhgef16
Rho guanine nucleotide exchange factor (GEF) 16
chr11_+_30073930 0.31 ENSDART00000127075
ugt1b1
UDP glucuronosyltransferase 1 family, polypeptide B1
chr13_-_49921086 0.31 ENSDART00000165066
eif2ak2
eukaryotic translation initiation factor 2-alpha kinase 2
chr16_+_46327528 0.31 ENSDART00000040769
nr2f5
nuclear receptor subfamily 2, group F, member 5
chr21_+_15774697 0.30 ENSDART00000122015
fam169ab
family with sequence similarity 169, member Ab
chr8_-_28323246 0.30 ENSDART00000005583
kdm5bb
lysine (K)-specific demethylase 5Bb
chr20_+_32594366 0.30 ENSDART00000145175
si:ch73-257c13.2
si:ch73-257c13.2
chr15_+_20303330 0.30 ENSDART00000152473
spint2
serine peptidase inhibitor, Kunitz type, 2
chr15_+_20303673 0.30 ENSDART00000152473
spint2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_26386711 0.29 ENSDART00000089836
jarid2b
jumonji, AT rich interactive domain 2b
chr5_+_23555868 0.29 ENSDART00000124379
gabarapa
GABA(A) receptor-associated protein a
chr5_+_36055362 0.29 ENSDART00000015240
capns1a
calpain, small subunit 1 a
chr24_-_18302095 0.28 ENSDART00000144203
ENSDART00000146024
sec61g
Sec61 translocon gamma subunit
chr14_+_7626822 0.28 ENSDART00000109941
cxxc5b
CXXC finger protein 5b
chr22_+_26543146 0.28

chr21_+_44586326 0.28

chr2_-_10192027 0.28 ENSDART00000100709
imp3
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr14_-_1187074 0.27 ENSDART00000106672
arl9
ADP-ribosylation factor-like 9
chr10_-_42318897 0.27 ENSDART00000134890
ENSDART00000099259
dusp11
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
chr20_+_25726978 0.27 ENSDART00000164264
ppat
phosphoribosyl pyrophosphate amidotransferase
chr16_+_17808913 0.27 ENSDART00000149596
si:dkey-87o1.2
si:dkey-87o1.2
chr6_-_51538315 0.27

chr19_+_14490203 0.26 ENSDART00000164386
arid1ab
AT rich interactive domain 1Ab (SWI-like)
chr15_+_19389071 0.26 ENSDART00000164184
vps26b
VPS26 retromer complex component B
chr8_-_23762309 0.26 ENSDART00000141879
si:ch211-163l21.7
si:ch211-163l21.7
chr23_+_10211543 0.26 ENSDART00000048073
zgc:171775
zgc:171775
chr4_-_72115050 0.25 ENSDART00000174274
BX855614.4
ENSDARG00000105816
chr6_-_28231995 0.25 ENSDART00000131126
bcl6a
B-cell CLL/lymphoma 6a (zinc finger protein 51)
chr25_-_16547149 0.25 ENSDART00000104110
slc25a18
solute carrier family 25 (glutamate carrier), member 18
chr15_+_23861042 0.25

chr5_+_36295353 0.25 ENSDART00000135776
srsf7a
serine/arginine-rich splicing factor 7a
chr6_+_26957509 0.25 ENSDART00000153595
farp2
FERM, RhoGEF and pleckstrin domain protein 2
chr13_-_36996246 0.25 ENSDART00000133242
syne2b
spectrin repeat containing, nuclear envelope 2b
chr14_-_38469172 0.24 ENSDART00000159159
ENSDARG00000100564
ENSDARG00000100564
chr11_-_2223434 0.24

chr15_+_19388905 0.24 ENSDART00000149926
vps26b
VPS26 retromer complex component B
chr13_-_31165867 0.23 ENSDART00000030946
prdm8
PR domain containing 8
chr19_-_48144752 0.23 ENSDART00000158979
c19h1orf109
c19h1orf109 homolog (H. sapiens)
chr18_-_14891913 0.23 ENSDART00000018502
mapk12a
mitogen-activated protein kinase 12a
chr14_-_1186858 0.22 ENSDART00000106672
arl9
ADP-ribosylation factor-like 9
chr14_-_1186789 0.22

chr16_+_16941228 0.22 ENSDART00000142155
myh14
myosin, heavy chain 14, non-muscle
chr1_+_39545535 0.22 ENSDART00000045697
zgc:56493
zgc:56493
chr10_-_40904685 0.21

chr6_+_7376428 0.21 ENSDART00000057823
pa2g4a
proliferation-associated 2G4, a
chr4_+_72666635 0.21 ENSDART00000166994
trim24
tripartite motif containing 24
chr7_-_981435 0.21 ENSDART00000101799
alpk1
alpha-kinase 1
chr2_+_30911143 0.21 ENSDART00000132645
chmp5a
charged multivesicular body protein 5a
chr11_-_36088889 0.20 ENSDART00000146495
psma5
proteasome subunit alpha 5
chr13_-_37482524 0.20 ENSDART00000140230
zgc:123068
zgc:123068
chr24_+_39139469 0.19 ENSDART00000085565
capn15
calpain 15
chr17_-_21258714 0.19 ENSDART00000157518
hspa12a
heat shock protein 12A
chr6_-_39524075 0.19 ENSDART00000065038
atf1
activating transcription factor 1
chr13_+_49527181 0.19 ENSDART00000176643
CABZ01084653.1
ENSDARG00000106801
chr25_+_18487408 0.18 ENSDART00000148741
met
MET proto-oncogene, receptor tyrosine kinase
chr20_-_34865344 0.18 ENSDART00000142482
paqr8
progestin and adipoQ receptor family member VIII
chr16_+_42868905 0.18 ENSDART00000156601
si:ch211-135n15.2
si:ch211-135n15.2
chr9_+_19655550 0.18 ENSDART00000111973
pde9a
phosphodiesterase 9A
chr18_-_44539130 0.18

chr14_-_6669062 0.17

chr19_+_38580804 0.17 ENSDART00000160756
phf14
PHD finger protein 14
chr16_-_1736470 0.17 ENSDART00000124660
ascc3
activating signal cointegrator 1 complex subunit 3
chr17_+_16082472 0.16 ENSDART00000133154
znf395a
zinc finger protein 395a
chr7_+_30516734 0.16 ENSDART00000174000
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr6_-_34237257 0.16 ENSDART00000102391
dmrt2b
doublesex and mab-3 related transcription factor 2b
chr25_+_4490129 0.16

chr24_-_24023167 0.16 ENSDART00000080671
eif1axb
eukaryotic translation initiation factor 1A, X-linked, b
chr17_+_31205274 0.16 ENSDART00000155580
ccdc32
coiled-coil domain containing 32
chr12_-_4584327 0.15

chr11_-_1792616 0.15

chr8_+_26037704 0.14

chr21_+_3017623 0.14

chr11_-_2274344 0.14 ENSDART00000158266
ENSDART00000104570
znf740a
zinc finger protein 740a
chr23_+_1024493 0.14 ENSDART00000143391
si:zfos-905g2.1
si:zfos-905g2.1
chr13_-_25418278 0.14 ENSDART00000077655
ENSDART00000168099
ENSDART00000135788
mcmbp
minichromosome maintenance complex binding protein
chr13_+_25418877 0.14 ENSDART00000169199
sec23ip
SEC23 interacting protein
chr6_-_40469263 0.13 ENSDART00000062724
crbn
cereblon
chr19_+_48144910 0.13 ENSDART00000149705
cdca8
cell division cycle associated 8
chr8_-_47156995 0.13

chr8_+_47909655 0.13

chr1_-_58183299 0.12 ENSDART00000166615
dnm2b
dynamin 2b
chr19_+_38580844 0.12 ENSDART00000160756
phf14
PHD finger protein 14
chr14_-_6680812 0.12 ENSDART00000060990
eif4ebp3l
eukaryotic translation initiation factor 4E binding protein 3, like
chr5_-_32282404 0.12 ENSDART00000166698
lrsam1
leucine rich repeat and sterile alpha motif containing 1
chr23_+_2614658 0.12

chr14_+_7626683 0.12 ENSDART00000171657
cxxc5b
CXXC finger protein 5b
chr16_-_4780901 0.12 ENSDART00000029485
arnt
aryl hydrocarbon receptor nuclear translocator
chr4_+_5634025 0.11 ENSDART00000028941
mrps18a
mitochondrial ribosomal protein S18A
chr17_+_10161999 0.11 ENSDART00000170274
foxa1
forkhead box A1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0043589 skin morphogenesis(GO:0043589)
0.3 0.9 GO:0070126 mitochondrial translational termination(GO:0070126)
0.3 3.6 GO:0051923 sulfation(GO:0051923)
0.2 1.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.2 0.9 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.2 0.9 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.2 0.7 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.2 4.0 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.2 1.2 GO:0033700 phospholipid efflux(GO:0033700)
0.1 0.4 GO:0021563 glossopharyngeal nerve development(GO:0021563) abducens nucleus development(GO:0021742)
0.1 1.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 3.0 GO:0060030 dorsal convergence(GO:0060030)
0.1 0.3 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.1 0.4 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 1.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 1.4 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 1.6 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1 1.4 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.1 2.7 GO:0051693 regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835) actin filament capping(GO:0051693)
0.1 1.7 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.1 1.1 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.2 GO:0070920 regulation of production of small RNA involved in gene silencing by RNA(GO:0070920) regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798)
0.1 0.6 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.6 GO:0050994 regulation of lipid catabolic process(GO:0050994)
0.0 2.0 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.4 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.4 GO:0014743 regulation of muscle hypertrophy(GO:0014743) muscle hypertrophy(GO:0014896)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.2 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 1.0 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.2 GO:0015740 C4-dicarboxylate transport(GO:0015740)
0.0 0.5 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.2 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.3 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.3 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.1 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.1 GO:0009410 response to xenobiotic stimulus(GO:0009410)
0.0 0.2 GO:0019934 cGMP-mediated signaling(GO:0019934) cGMP metabolic process(GO:0046068)
0.0 0.2 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0006226 dUMP biosynthetic process(GO:0006226) dUMP metabolic process(GO:0046078)
0.0 1.8 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.3 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.9 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 1.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.0 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0048319 axial mesoderm morphogenesis(GO:0048319)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:0008091 spectrin(GO:0008091)
0.2 0.9 GO:0016600 flotillin complex(GO:0016600)
0.1 1.1 GO:0030669 clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 0.4 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.1 0.3 GO:0034457 Mpp10 complex(GO:0034457)
0.1 1.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.5 GO:0030904 retromer complex(GO:0030904)
0.0 1.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0071256 translocon complex(GO:0071256)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 1.7 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.9 GO:0008305 integrin complex(GO:0008305)
0.0 0.1 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.3 GO:0035060 brahma complex(GO:0035060)
0.0 0.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 1.8 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.3 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.7 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0000421 autophagosome membrane(GO:0000421)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 0.8 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.2 0.9 GO:0008097 5S rRNA binding(GO:0008097)
0.2 0.7 GO:0019808 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.2 1.1 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.1 1.3 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.1 1.6 GO:2001069 glycogen binding(GO:2001069)
0.1 3.7 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.3 GO:0004044 amidophosphoribosyltransferase activity(GO:0004044)
0.1 0.9 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.6 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.4 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 3.6 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 0.9 GO:0001968 fibronectin binding(GO:0001968)
0.1 1.1 GO:0005518 collagen binding(GO:0005518)
0.1 1.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 2.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.4 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 1.9 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.8 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 1.1 GO:0030276 clathrin binding(GO:0030276)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.0 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0 0.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.1 0.9 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 2.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.4 PID ATM PATHWAY ATM pathway
0.0 0.3 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.8 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.9 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 1.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.0 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants