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Results for bhlhe23+si:ch211-196c10.13_bhlhe22_neurod2_bhlha15

Z-value: 1.06

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Transcription factors associated with bhlhe23+si:ch211-196c10.13_bhlhe22_neurod2_bhlha15

Gene Symbol Gene ID Gene Info
bhlhe23
ENSDARG00000037588 basic helix-loop-helix family, member e23
si_ch211-196c10.13
ENSDARG00000096756 si_ch211-196c10.13
bhlhe22
ENSDARG00000058039 basic helix-loop-helix family, member e22
neurod2
ENSDARG00000016854 neuronal differentiation 2
bhlha15
ENSDARG00000045166 basic helix-loop-helix family, member a15

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
bhlhe22dr10_dc_chr24_+_24316486_243165190.946.4e-08Click!
bhlha15dr10_dc_chr12_+_17632953_176330110.282.9e-01Click!

Activity profile of bhlhe23+si:ch211-196c10.13_bhlhe22_neurod2_bhlha15 motif

Sorted Z-values of bhlhe23+si:ch211-196c10.13_bhlhe22_neurod2_bhlha15 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of bhlhe23+si:ch211-196c10.13_bhlhe22_neurod2_bhlha15

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr20_-_22576513 6.31 ENSDART00000103510
pdgfra
platelet-derived growth factor receptor, alpha polypeptide
chr14_+_45895103 5.66

chr19_-_22182031 4.20 ENSDART00000104279
znf516
zinc finger protein 516
chr13_-_24181106 4.06 ENSDART00000004420
rab4a
RAB4a, member RAS oncogene family
chr20_+_34423970 4.01 ENSDART00000061659
ivns1abpa
influenza virus NS1A binding protein a
chr13_+_31155208 3.56 ENSDART00000148352
gdf10a
growth differentiation factor 10a
chr5_+_36093701 3.24 ENSDART00000019259
dlb
deltaB
chr14_+_2969679 3.11 ENSDART00000044678
ENSDARG00000034011
ENSDARG00000034011
chr17_-_756401 2.95 ENSDART00000157622
zbtb42
zinc finger and BTB domain containing 42
chr3_-_30554400 2.92 ENSDART00000151097
si:ch211-51c14.1
si:ch211-51c14.1
chr22_-_37468331 2.88 ENSDART00000160940
SOX2OT_exon1
SOX2 overlapping transcript exon 1
chr2_-_50638153 2.62 ENSDART00000108900
cntnap2b
contactin associated protein-like 2b
chr24_+_30343717 2.56 ENSDART00000162377
FP085414.1
ENSDARG00000100270
chr3_+_28822408 2.48 ENSDART00000133528
lgals2a
lectin, galactoside-binding, soluble, 2a
chr2_-_28154388 2.41 ENSDART00000161864
zgc:123035
zgc:123035
chr13_+_11305781 2.33

chr15_-_4322875 2.33 ENSDART00000173311
si:ch211-117a13.2
si:ch211-117a13.2
chr3_-_30554490 2.24 ENSDART00000151097
si:ch211-51c14.1
si:ch211-51c14.1
chr15_-_18159904 2.15 ENSDART00000170874
phldb1b
pleckstrin homology-like domain, family B, member 1b
chr3_+_40667131 2.13 ENSDART00000033713
arpc1b
actin related protein 2/3 complex, subunit 1B
chr6_+_54134129 2.11 ENSDART00000156554
hmga1b
high mobility group AT-hook 1b
chr18_-_25659136 2.11 ENSDART00000138861
si:ch211-13k12.2
si:ch211-13k12.2
chr3_+_50511676 2.07 ENSDART00000102202
ppap2d
phosphatidic acid phosphatase type 2D
chr16_-_45258675 1.95 ENSDART00000158855
fxyd1
FXYD domain containing ion transport regulator 1 (phospholemman)
chr23_-_28286971 1.94

chr6_+_49366870 1.84 ENSDART00000109628
kcna3a
potassium voltage-gated channel, shaker-related subfamily, member 3a
chr13_+_11305846 1.81

chr19_-_15951003 1.80 ENSDART00000133059
cited4a
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4a
chr3_+_31490043 1.79 ENSDART00000076636
fzd2
frizzled class receptor 2
chr8_-_17580655 1.77

chr7_-_15164722 1.76 ENSDART00000172147
ENSDARG00000036809
ENSDARG00000036809
chr10_+_22043094 1.75 ENSDART00000035188
kcnip1b
Kv channel interacting protein 1 b
chr1_-_15814788 1.61 ENSDART00000169081
mtmr7b
myotubularin related protein 7b
chr5_-_27394386 1.59 ENSDART00000171611
ppp3cca
protein phosphatase 3, catalytic subunit, gamma isozyme, a
chr1_-_44942047 1.57 ENSDART00000044057
sept3
septin 3
chr9_+_30279907 1.56 ENSDART00000102981
col8a1a
collagen, type VIII, alpha 1a
chr24_+_9124068 1.55

chr5_-_41645167 1.47

chr24_+_30343687 1.47 ENSDART00000162377
FP085414.1
ENSDARG00000100270
chr2_-_55737505 1.42 ENSDART00000059003
rx2
retinal homeobox gene 2
chr6_+_44891187 1.41

chr18_-_14868444 1.35 ENSDART00000045232
mtss1la
metastasis suppressor 1-like a
chr22_+_19605843 1.33 ENSDART00000124646
rgmd
RGM domain family, member D
chr21_+_11375961 1.33 ENSDART00000158936
grin1a
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr19_+_32317583 1.31 ENSDART00000151218
tpd52
tumor protein D52
chr6_+_44891278 1.31

chr14_+_45895037 1.29

chr14_-_15651090 1.26 ENSDART00000169197
flt4
fms-related tyrosine kinase 4
chr12_-_6144233 1.24 ENSDART00000152292
a1cf
apobec1 complementation factor
chr20_+_6783810 1.20 ENSDART00000169966
igfbp3
insulin-like growth factor binding protein 3
chr5_+_25346893 1.14

chr3_+_24564249 1.12 ENSDART00000111769
mkl1a
megakaryoblastic leukemia (translocation) 1a
chr9_-_42894582 1.11 ENSDART00000144744
col5a2a
collagen, type V, alpha 2a
chr21_-_19280266 1.06 ENSDART00000141596
gpat3
glycerol-3-phosphate acyltransferase 3
chr8_-_27839244 1.06 ENSDART00000136562
cttnbp2nlb
CTTNBP2 N-terminal like b
chr19_-_22802777 1.03 ENSDART00000151234
eppk1
epiplakin 1
chr24_+_13780640 1.03 ENSDART00000136443
ENSDART00000081595
ENSDART00000012253
eya1
EYA transcriptional coactivator and phosphatase 1
chr24_+_14302079 1.00 ENSDART00000168059
prdm14
PR domain containing 14
chr11_-_34259173 0.98 ENSDART00000114004
pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr14_+_25519707 0.97 ENSDART00000005499
glra1
glycine receptor, alpha 1
chr14_-_31514534 0.96 ENSDART00000003345
arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr8_+_39964695 0.94 ENSDART00000073782
ggt5a
gamma-glutamyltransferase 5a
chr17_-_20538582 0.94

chr5_+_18836714 0.94

chr11_+_6675108 0.93 ENSDART00000139454
pde4cb
phosphodiesterase 4C, cAMP-specific b
chr17_+_25463178 0.92 ENSDART00000139451
aim1a
crystallin beta-gamma domain containing 1a
chr5_+_18836775 0.91

chr3_+_24067387 0.87 ENSDART00000055609
atf4b
activating transcription factor 4b
chr20_+_18803167 0.86 ENSDART00000019476
eif5
eukaryotic translation initiation factor 5
chr4_+_5498355 0.86 ENSDART00000150785
mapk11
mitogen-activated protein kinase 11
chr14_+_20862466 0.84 ENSDART00000059796
ENSDARG00000019213
ENSDARG00000019213
chr2_-_5233883 0.83 ENSDART00000163728
dlg1l
discs, large (Drosophila) homolog 1, like
chr9_-_42928777 0.69 ENSDART00000136728
fkbp7
FK506 binding protein 7
chr23_-_18131105 0.67 ENSDART00000173102
zgc:92287
zgc:92287
chr17_-_10682357 0.66 ENSDART00000064597
lgals3b
lectin, galactoside binding soluble 3b
chr16_+_53568814 0.63 ENSDART00000154189
rbm24b
RNA binding motif protein 24b
chr19_-_22983970 0.63 ENSDART00000160153
pleca
plectin a
chr6_-_42143595 0.62 ENSDART00000085472
grm2a
glutamate receptor, metabotropic 2a
chr4_+_12618256 0.62 ENSDART00000112860
ENSDART00000134362
lmo3
LIM domain only 3
chr22_-_17026124 0.61 ENSDART00000138382
nfia
nuclear factor I/A
chr14_+_33382973 0.54 ENSDART00000132488
apln
apelin
chr4_+_14361566 0.53 ENSDART00000007103
nuak1a
NUAK family, SNF1-like kinase, 1a
chr1_-_28241500 0.51 ENSDART00000019770
gpm6ba
glycoprotein M6Ba
chr14_-_33596430 0.50 ENSDART00000112438
si:ch73-335m24.5
si:ch73-335m24.5
chr8_+_25590886 0.49 ENSDART00000062385
slc38a5a
solute carrier family 38, member 5a
chr12_+_3189489 0.49 ENSDART00000010569
g6pc3
glucose 6 phosphatase, catalytic, 3
chr5_+_29327479 0.47

chr13_+_11305968 0.46

chr3_+_52645074 0.46 ENSDART00000058958
atp13a1
ATPase type 13A1
chr4_-_16365281 0.45 ENSDART00000139919
lum
lumican
chr3_+_23604393 0.45

chr5_+_29327363 0.44

chr1_+_46794847 0.44 ENSDART00000140846
lrrc58a
leucine rich repeat containing 58a
chr19_-_22984081 0.43 ENSDART00000160153
pleca
plectin a
chr4_+_14361655 0.43 ENSDART00000007103
nuak1a
NUAK family, SNF1-like kinase, 1a
chr22_-_17026421 0.43 ENSDART00000138382
nfia
nuclear factor I/A
chr4_+_27139902 0.41

chr3_+_40667088 0.41 ENSDART00000033713
arpc1b
actin related protein 2/3 complex, subunit 1B
chr18_+_12179227 0.41 ENSDART00000162067
ENSDART00000168386
fgd4a
FYVE, RhoGEF and PH domain containing 4a
chr3_-_52419408 0.40 ENSDART00000154260
si:dkey-210j14.4
si:dkey-210j14.4
chr14_-_32485197 0.40

chr6_+_39225133 0.40 ENSDART00000154991
b4galnt1b
beta-1,4-N-acetyl-galactosaminyl transferase 1b
chr7_-_50122602 0.39 ENSDART00000065868
vps33b
vacuolar protein sorting 33B
chr20_-_36672566 0.39 ENSDART00000062893
enah
enabled homolog (Drosophila)
chr21_-_24552672 0.39

chr14_-_31522323 0.38 ENSDART00000172870
rbmx
RNA binding motif protein, X-linked
chr4_+_12618485 0.37 ENSDART00000112860
lmo3
LIM domain only 3
chr6_-_10728582 0.36 ENSDART00000151102
notum2
notum pectinacetylesterase 2
chr20_+_30917073 0.36

chr1_-_8968543 0.35 ENSDART00000126877
ENSDART00000123773
ENSDART00000126996
ugt5b1
ugt5b3
UDP glucuronosyltransferase 5 family, polypeptide B1
UDP glucuronosyltransferase 5 family, polypeptide B3
chr3_-_35472632 0.35 ENSDART00000055269
gng13b
guanine nucleotide binding protein (G protein), gamma 13b
chr5_+_5186074 0.34

chr2_+_35505943 0.34 ENSDART00000131248
CR855337.1
ENSDARG00000094295
chr23_-_7048903 0.33 ENSDART00000149656
edem2
ER degradation enhancer, mannosidase alpha-like 2
chr2_-_53156364 0.32

chr11_+_30035395 0.31 ENSDART00000122756
si:dkey-163f14.6
si:dkey-163f14.6
chr16_+_13534390 0.28 ENSDART00000157396
ENSDARG00000022807
ENSDARG00000022807
chr17_+_11950934 0.27

chr3_+_35276575 0.27 ENSDART00000102994
rbbp6
retinoblastoma binding protein 6
chr5_+_29327447 0.26

chr10_+_19568414 0.25 ENSDART00000162912
vsig8a
V-set and immunoglobulin domain containing 8a
chr23_-_4080767 0.24 ENSDART00000159780
slc9a8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr6_+_7395817 0.23 ENSDART00000150939
ENSDART00000151114
myh10
myosin, heavy chain 10, non-muscle
chr8_+_36888422 0.22

chr19_-_7621797 0.22 ENSDART00000143958
lix1l
limb and CNS expressed 1 like
chr19_-_41819752 0.21 ENSDART00000167772
shfm1
split hand/foot malformation (ectrodactyly) type 1
chr10_+_42546351 0.20 ENSDART00000020000
COX5B
cytochrome c oxidase subunit 5B
chr9_+_30183691 0.19 ENSDART00000012447
tmem30c
transmembrane protein 30C
chr13_-_8968218 0.19 ENSDART00000144142
ENSDART00000144714
HTRA2 (1 of many)
HtrA serine peptidase 2
chr13_-_10539949 0.19 ENSDART00000132393
slc3a1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr20_-_43281269 0.18

chr13_+_22150568 0.18 ENSDART00000173379
ENSDART00000173258
usp54a
ubiquitin specific peptidase 54a
chr9_+_33049445 0.18 ENSDART00000168992
si:dkey-145p14.5
si:dkey-145p14.5
chr9_+_3578084 0.17

chr4_-_72132319 0.16 ENSDART00000159313
si:dkey-262g12.10
si:dkey-262g12.10
chr24_-_8365022 0.14 ENSDART00000149025
slc35b3
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
chr3_+_24067430 0.14 ENSDART00000055609
atf4b
activating transcription factor 4b
chr19_-_7487978 0.13 ENSDART00000151137
oxr1b
oxidation resistance 1b
chr23_-_18131038 0.12 ENSDART00000173385
zgc:92287
zgc:92287
chr24_+_2678808 0.12

chr16_-_52761159 0.11 ENSDART00000111869
ubr5
ubiquitin protein ligase E3 component n-recognin 5
chr9_+_33049549 0.11 ENSDART00000121751
si:dkey-145p14.5
si:dkey-145p14.5
chr8_+_39964882 0.10 ENSDART00000134452
ggt5a
gamma-glutamyltransferase 5a
chr5_-_2540097 0.10

chr16_+_41922407 0.09

chr19_-_22984023 0.09 ENSDART00000160153
pleca
plectin a
chr3_-_36316264 0.09 ENSDART00000168733
glyr1
glyoxylate reductase 1 homolog (Arabidopsis)
chr2_+_50873893 0.08

chr6_+_29799599 0.07

chr21_+_18913329 0.06 ENSDART00000036172
crkl
v-crk avian sarcoma virus CT10 oncogene homolog-like
chr21_+_21575563 0.05 ENSDART00000008099
b9d2
B9 protein domain 2
chr11_+_2641147 0.05 ENSDART00000132768
mapk14b
mitogen-activated protein kinase 14b
chr6_-_16267239 0.03 ENSDART00000089445
agap1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr22_+_11827925 0.03 ENSDART00000179540
mras
muscle RAS oncogene homolog
chr20_-_43281081 0.03

chr17_-_14621328 0.01

chr8_+_27536121 0.00 ENSDART00000016696
rhocb
ras homolog family member Cb
chr25_+_3168376 0.00 ENSDART00000030683
tmpob
thymopoietin b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.3 GO:0003315 heart rudiment formation(GO:0003315)
0.6 1.3 GO:0035474 selective angioblast sprouting(GO:0035474)
0.4 5.2 GO:0097320 membrane tubulation(GO:0097320)
0.4 2.5 GO:0090303 positive regulation of wound healing(GO:0090303)
0.3 1.0 GO:0032355 glutathione catabolic process(GO:0006751) response to estradiol(GO:0032355)
0.3 4.1 GO:0032482 Rab protein signal transduction(GO:0032482)
0.2 1.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 0.7 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.2 0.6 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.2 0.5 GO:0042756 drinking behavior(GO:0042756)
0.2 1.0 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.2 1.0 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.2 0.5 GO:0098810 neurotransmitter uptake(GO:0001504) regulation of neurotransmitter uptake(GO:0051580) neurotransmitter reuptake(GO:0098810)
0.2 1.0 GO:0034969 histone arginine methylation(GO:0034969)
0.2 1.3 GO:0030183 B cell differentiation(GO:0030183)
0.2 0.5 GO:1902024 serine transport(GO:0032329) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 1.8 GO:0003306 Wnt signaling pathway involved in heart development(GO:0003306) Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.1 1.6 GO:0014028 notochord formation(GO:0014028)
0.1 2.5 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 0.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 3.6 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 3.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 1.0 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 1.1 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 1.4 GO:0097178 ruffle assembly(GO:0097178)
0.1 0.4 GO:0048025 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 1.2 GO:0016556 mRNA modification(GO:0016556)
0.1 0.9 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 1.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.4 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 3.7 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 2.1 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.6 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0 0.4 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 1.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:1990697 protein depalmitoleylation(GO:1990697)
0.0 0.2 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 0.5 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.4 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.5 GO:0030199 collagen fibril organization(GO:0030199)
0.0 1.6 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 2.1 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 0.1 GO:1900045 negative regulation of histone ubiquitination(GO:0033183) histone H2A K63-linked ubiquitination(GO:0070535) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.0 GO:0060143 positive regulation of syncytium formation by plasma membrane fusion(GO:0060143) positive regulation of myoblast fusion(GO:1901741)
0.0 0.2 GO:0048669 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.4 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0036372 opsin transport(GO:0036372)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.4 1.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.4 1.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3 1.0 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.2 1.6 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.2 2.1 GO:0045180 basal cortex(GO:0045180)
0.1 2.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.7 GO:0001772 immunological synapse(GO:0001772)
0.1 1.1 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.4 GO:0033263 CORVET complex(GO:0033263)
0.1 0.4 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 1.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.7 GO:0045095 keratin filament(GO:0045095)
0.0 7.5 GO:0043235 receptor complex(GO:0043235)
0.0 1.6 GO:0005581 collagen trimer(GO:0005581)
0.0 2.6 GO:0005911 cell-cell junction(GO:0005911)
0.0 1.0 GO:0030027 lamellipodium(GO:0030027)
0.0 5.8 GO:0005615 extracellular space(GO:0005615)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0016936 galactoside binding(GO:0016936)
0.3 1.0 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.3 1.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.2 0.6 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.2 1.0 GO:0019215 intermediate filament binding(GO:0019215)
0.2 3.2 GO:0005112 Notch binding(GO:0005112)
0.2 1.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.2 1.0 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 1.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 1.3 GO:0015026 coreceptor activity(GO:0015026)
0.1 2.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.1 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.5 GO:0031704 apelin receptor binding(GO:0031704)
0.1 5.8 GO:0019838 growth factor binding(GO:0019838)
0.1 0.5 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 1.6 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.1 0.5 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 2.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 3.6 GO:0005125 cytokine activity(GO:0005125)
0.0 0.9 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.3 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.5 GO:0019203 carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308)
0.0 1.2 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 5.5 GO:0003924 GTPase activity(GO:0003924)
0.0 0.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.4 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 1.8 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 3.5 GO:0005543 phospholipid binding(GO:0005543)
0.0 1.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.4 GO:0017069 snRNA binding(GO:0017069)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.2 6.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 4.1 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 0.9 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 1.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 3.9 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.3 1.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 1.0 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 6.2 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 0.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.6 REACTOME MRNA PROCESSING Genes involved in mRNA Processing