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Results for bsx+nanog

Z-value: 0.92

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Transcription factors associated with bsx+nanog

Gene Symbol Gene ID Gene Info
ENSDARG00000068976 brain-specific homeobox
ENSDARG00000075113 nanog homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nanogdr10_dc_chr24_+_12689711_126898650.931.7e-07Click!
bsxdr10_dc_chr10_-_30006277_30006282-0.871.2e-05Click!

Activity profile of bsx+nanog motif

Sorted Z-values of bsx+nanog motif

Network of associatons between targets according to the STRING database.

First level regulatory network of bsx+nanog

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_-_6442588 3.68 ENSDART00000137879
zgc:162969
chr11_-_1524107 3.49 ENSDART00000110097
si:ch73-303b9.1
chr19_-_20819101 3.41 ENSDART00000137590
deleted in azoospermia-like
chr21_+_25740782 3.34 ENSDART00000021620
claudin d
chr16_+_39209567 3.22 ENSDART00000121756
syntabulin (syntaxin-interacting)
chr19_-_20819477 2.87 ENSDART00000151356
deleted in azoospermia-like
chr19_-_18664720 2.84 ENSDART00000108627
sorting nexin 10a
chr24_-_14446593 2.60

chr23_-_35691369 2.53 ENSDART00000142369
major facilitator superfamily domain containing 5
chr17_+_16038358 2.48 ENSDART00000155336
si:ch73-204p21.2
chr22_-_20670164 2.43 ENSDART00000169077
oogenesis-related gene
chr14_+_34150130 2.43 ENSDART00000132193
ENSDART00000141058
wingless-type MMTV integration site family, member 8a
ENSDARG00000105311
chr13_-_6875290 2.40

chr15_-_25164321 2.03 ENSDART00000154628
family with sequence similarity 101, member B
chr21_-_32747592 1.99

chr5_+_29193876 1.99 ENSDART00000045410
Thy-1 cell surface antigen
chr2_-_27892824 1.97

chr17_+_16038103 1.91 ENSDART00000155005
si:ch73-204p21.2
chr10_-_21404605 1.91 ENSDART00000125167
avidin
chr10_-_25246786 1.87 ENSDART00000036906
karyopherin alpha 7 (importin alpha 8)
KN149710v1_+_38638 1.79

chr19_+_15536640 1.77 ENSDART00000098970
lin-28 homolog A (C. elegans)
chr20_-_23527234 1.74 ENSDART00000004625
zygote arrest 1
KN150266v1_-_68652 1.71

chr10_-_34058331 1.69 ENSDART00000046599
zygote arrest 1-like
chr10_+_19625897 1.69

chr20_+_37023072 1.68 ENSDART00000155058
ENSDARG00000096706
chr14_+_23420053 1.64 ENSDART00000006373
Nedd4 family interacting protein 1
chr24_+_39750793 1.55 ENSDART00000133284
LUC7-like (S. cerevisiae)
chr8_-_44247277 1.52

chr14_+_29932533 1.51 ENSDART00000017122
N-acylsphingosine amidohydrolase (acid ceramidase) 1a
chr6_+_28218420 1.51 ENSDART00000171216
ENSDART00000171377
si:ch73-14h10.2
chr15_-_16241412 1.50 ENSDART00000156352
si:ch211-259g3.4
chr16_+_47283253 1.50 ENSDART00000062507
islet cell autoantigen 1
chr5_+_36168475 1.46 ENSDART00000146854
MAP/microtubule affinity-regulating kinase 4a
chr10_+_6925373 1.45 ENSDART00000128866
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr7_+_15479700 1.44

chr6_+_49411169 1.44

chr18_-_43890836 1.44 ENSDART00000087382
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr16_+_42567707 1.41 ENSDART00000166640
si:ch211-215k15.5
chr23_-_32267833 1.41

KN150702v1_-_111659 1.40 ENSDART00000165431
protein phosphatase 1 catalytic subunit gamma
chr5_-_8712114 1.37 ENSDART00000134896
ENSDART00000147000
low-density lipoprotein receptor related-protein 13
chr10_-_34971926 1.35 ENSDART00000141201
cyclin A1
chr7_-_21571924 1.33 ENSDART00000166446
ENSDARG00000102693
chr5_+_58936399 1.32

chr1_-_39265484 1.31 ENSDART00000160066
inhibitor of growth family, member 2
chr20_-_28531087 1.26 ENSDART00000172133
ENSDARG00000105192
chr3_-_25142506 1.26 ENSDART00000145315
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr6_+_46430090 1.25 ENSDART00000064865
ENSDART00000133992
staufen double-stranded RNA binding protein 1
chr3_-_25142301 1.25 ENSDART00000145315
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr15_-_23484927 1.25 ENSDART00000148840
lysine (K)-specific methyltransferase 2A
chr23_+_28464194 1.24 ENSDART00000133736
ENSDARG00000093306
chr1_-_39265542 1.23 ENSDART00000160066
inhibitor of growth family, member 2
chr10_-_44713495 1.23 ENSDART00000076084
nucleophosmin/nucleoplasmin, 2b
chr23_+_28396415 1.23 ENSDART00000142179
baculoviral IAP repeat containing 5b
chr5_-_8712068 1.22 ENSDART00000134896
ENSDART00000147000
low-density lipoprotein receptor related-protein 13
chr7_+_24257251 1.20 ENSDART00000136473
ENSDARG00000079281
chr3_+_13034056 1.20

chr24_+_34183462 1.16 ENSDART00000143995
zgc:92591
chr20_-_28939553 1.16 ENSDART00000044462
myc associated factor X
chr3_-_25142556 1.15 ENSDART00000145315
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr21_-_39521698 1.14 ENSDART00000020174
dynein, light chain, LC8-type 2b
chr20_-_38884093 1.13 ENSDART00000153430
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a
chr11_-_44756789 1.13 ENSDART00000161712
synaptogyrin 2b
chr11_+_39664664 1.10 ENSDART00000102734
ENSDART00000137516
vesicle-associated membrane protein 3 (cellubrevin)
chr16_+_33209956 1.10 ENSDART00000101943
Ras-related GTP binding Ca
chr19_-_20819057 1.10 ENSDART00000136826
deleted in azoospermia-like
chr1_-_54570813 1.10 ENSDART00000098615
nanos homolog 3
chr20_-_28531019 1.09 ENSDART00000172133
ENSDARG00000105192
chr5_+_62681954 1.07 ENSDART00000137855
si:ch73-376l24.6
chr18_+_6417959 1.06 ENSDART00000110892
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr2_+_37194276 1.06 ENSDART00000048277
coatomer protein complex, subunit alpha
chr17_-_25630635 1.03 ENSDART00000149060
protein phosphatase 1, catalytic subunit, beta isozyme
chr17_+_28085497 1.02 ENSDART00000131638
ENSDARG00000054122
chr11_-_44859225 1.02 ENSDART00000163776
eukaryotic translation initiation factor 4A3
chr12_-_20494169 1.02 ENSDART00000105362
sorting nexin 11
chr3_-_33296077 1.01 ENSDART00000075495
ribosomal protein L23
chr2_-_54224744 1.01

chr2_-_26941084 1.00 ENSDART00000134685
ENSDART00000056787
zgc:113691
chr19_-_18664670 1.00 ENSDART00000108627
sorting nexin 10a
chr19_+_3115685 1.00 ENSDART00000127473
ENSDART00000126549
ENSDART00000024593
ENSDART00000082353
ENSDART00000141324
heat shock transcription factor 1
chr21_+_32046764 1.00

chr7_+_35163845 0.99 ENSDART00000173733
ENSDARG00000104955
chr7_-_56465369 0.99 ENSDART00000020967
casein kinase 2, alpha prime polypeptide a
chr12_-_33558248 0.99 ENSDART00000153457
transmembrane protein 94
chr1_+_21244200 0.99 ENSDART00000087729
lysine (K)-specific demethylase 4C
chr15_-_16241500 0.98 ENSDART00000156352
si:ch211-259g3.4
chr25_+_29219342 0.97 ENSDART00000108692
ENSDART00000077445
Pim-3 proto-oncogene, serine/threonine kinase
chr23_-_42918086 0.97 ENSDART00000102328
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr16_+_47283374 0.97 ENSDART00000062507
islet cell autoantigen 1
chr25_-_28630138 0.96

chr12_-_10529153 0.96 ENSDART00000047769
myoferlin
chr16_+_29574449 0.95 ENSDART00000148450
cathepsin S, ortholog2, tandem duplicate 1
chr19_+_3115791 0.94 ENSDART00000127473
ENSDART00000126549
ENSDART00000024593
ENSDART00000082353
ENSDART00000141324
heat shock transcription factor 1
chr20_+_27813565 0.93 ENSDART00000008306
zinc finger and BTB domain containing 1
chr12_+_19077980 0.92 ENSDART00000066393
pdgfa associated protein 1a
chr8_-_1833095 0.91 ENSDART00000114476
ENSDART00000091235
ENSDART00000140077
phosphatidylinositol 4-kinase, catalytic, alpha b
chr10_-_32550351 0.91 ENSDART00000129395
UV radiation resistance associated gene
chr16_+_25192196 0.91 ENSDART00000033211
zgc:66448
chr6_-_31798839 0.91

chr24_+_34183557 0.90 ENSDART00000143995
zgc:92591
chr12_+_47729417 0.90 ENSDART00000159120
polymerase (RNA) III (DNA directed) polypeptide A
chr11_-_6442490 0.88 ENSDART00000137879
zgc:162969
chr6_-_2037693 0.88 ENSDART00000159957
peroxisomal membrane protein 4
chr25_-_28630823 0.88 ENSDART00000165603
AT rich interactive domain 3B (BRIGHT-like)
chr2_-_38223813 0.87 ENSDART00000137395
apoptotic chromatin condensation inducer 1a
chr20_-_23355244 0.87

chr2_+_38305689 0.87 ENSDART00000170672
neural precursor cell expressed, developmentally down-regulated 8, like
chr5_+_6391432 0.87 ENSDART00000170564
ENSDART00000086666
sperm-tail PG-rich repeat containing 2
chr4_+_14983045 0.86 ENSDART00000067046
cation/H+ exchanger protein 1
chr23_-_42918055 0.84 ENSDART00000102328
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
KN150266v1_-_68620 0.84

chr5_+_62682097 0.84 ENSDART00000137855
si:ch73-376l24.6
chr11_-_6442547 0.83 ENSDART00000137879
zgc:162969
chr13_-_2259820 0.83 ENSDART00000168595
ELOVL fatty acid elongase 5
chr3_-_42949449 0.83 ENSDART00000161127
axin 1
chr14_-_26199859 0.82 ENSDART00000054175
ENSDART00000145625
SMAD family member 5
chr3_-_42949479 0.82 ENSDART00000161127
axin 1
chr6_+_40925259 0.82 ENSDART00000002728
ENSDART00000145153
eukaryotic translation initiation factor 4E nuclear import factor 1
chr23_+_28464298 0.81 ENSDART00000133736
ENSDARG00000093306
chr3_+_26113393 0.80 ENSDART00000103733
ATPase family, AAA domain containing 5a
chr22_+_1568354 0.80 ENSDART00000175704
si:ch211-255f4.11
chr7_-_23623141 0.79

chr3_+_28729443 0.79 ENSDART00000077235
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr8_-_23591293 0.79 ENSDART00000025024
solute carrier family 38, member 5b
chr8_-_21039978 0.78 ENSDART00000137606
ENSDART00000146532
zgc:112962
chr11_-_18078147 0.77 ENSDART00000177625
zgc:173545
chr3_-_26052785 0.77 ENSDART00000147517
si:ch211-11k18.4
chr19_-_20819028 0.77 ENSDART00000136826
deleted in azoospermia-like
chr2_-_26941232 0.76 ENSDART00000134685
ENSDART00000056787
zgc:113691
chr7_+_72925910 0.76 ENSDART00000175267
ENSDART00000179638
ENSDARG00000106453
chr2_+_38305772 0.76 ENSDART00000170672
neural precursor cell expressed, developmentally down-regulated 8, like
chr19_-_5186692 0.76 ENSDART00000037007
triosephosphate isomerase 1a
chr16_+_42567668 0.76 ENSDART00000166640
si:ch211-215k15.5
chr3_-_26113336 0.76 ENSDART00000103741
protein phosphatase 4, catalytic subunit a
chr5_-_56293700 0.76

chr18_+_2124267 0.75

chr6_+_18941135 0.75 ENSDART00000044519
connexin 44.2
chr23_+_28464143 0.75 ENSDART00000133736
ENSDARG00000093306
chr23_-_31986679 0.74 ENSDART00000085054
mitochondrial fission regulator 2
chr19_+_3115642 0.74 ENSDART00000127473
ENSDART00000126549
ENSDART00000024593
ENSDART00000082353
ENSDART00000141324
heat shock transcription factor 1
chr24_+_24025923 0.74 ENSDART00000127842
si:dkey-226l10.6
chr3_-_19890717 0.73 ENSDART00000104118
ENSDART00000170199
ataxin 7-like 3
chr20_-_29961498 0.73 ENSDART00000132278
ring finger protein 144ab
chr3_-_42949526 0.72 ENSDART00000161127
axin 1
chr10_-_35313462 0.72 ENSDART00000139107
proline rich 11
chr19_+_30211052 0.71 ENSDART00000051804
MARCKS-like 1b
chr25_+_29219116 0.71 ENSDART00000108692
ENSDART00000077445
Pim-3 proto-oncogene, serine/threonine kinase
chr10_+_22065599 0.71 ENSDART00000143461
nucleophosmin 1a (nucleolar phosphoprotein B23, numatrin)
chr2_+_30497550 0.71 ENSDART00000125933
family with sequence similarity 173, member B
chr7_+_66410947 0.71 ENSDART00000027616
ENSDART00000162763
eukaryotic translation initiation factor 4, gamma 2a
chr24_+_24025701 0.70 ENSDART00000127842
si:dkey-226l10.6
chr20_-_29961589 0.69 ENSDART00000132278
ring finger protein 144ab
chr10_-_11011134 0.69 ENSDART00000138041
exonuclease 3'-5' domain containing 3
chr1_+_21244242 0.69 ENSDART00000087729
lysine (K)-specific demethylase 4C
chr10_-_44713414 0.69 ENSDART00000076084
nucleophosmin/nucleoplasmin, 2b
chr12_-_13690748 0.68 ENSDART00000078021
forkhead box H1
chr24_-_14446522 0.68

chr11_+_16017857 0.67 ENSDART00000081054
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr23_-_17078167 0.67 ENSDART00000126841
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2
chr20_+_46524223 0.67 ENSDART00000153290
RAD51 recombinase
chr2_-_26940965 0.66 ENSDART00000134685
ENSDART00000056787
zgc:113691
chr6_-_12787256 0.66 ENSDART00000157139
transmembrane BAX inhibitor motif containing 1a
chr6_-_12786937 0.66 ENSDART00000157139
transmembrane BAX inhibitor motif containing 1a
chr10_+_516924 0.66 ENSDART00000128275
neuropeptide FF receptor 1 like 3
chr11_-_12024136 0.66 ENSDART00000111919
sp2 transcription factor
chr20_-_34851706 0.65 ENSDART00000148066
zinc finger protein 395b
chr12_-_31958774 0.65 ENSDART00000086531
cytochrome c oxidase assembly homolog 11 (yeast)
KN150702v1_-_111618 0.64 ENSDART00000165431
protein phosphatase 1 catalytic subunit gamma
chr21_-_36710989 0.64 ENSDART00000086060
mitochondrial ribosomal protein L22
chr3_-_42949189 0.64 ENSDART00000161127
axin 1
chr10_+_516885 0.63 ENSDART00000128275
neuropeptide FF receptor 1 like 3
chr5_+_68036497 0.63 ENSDART00000017849
hairy and enhancer of split related-7
chr2_-_38223766 0.63 ENSDART00000137395
apoptotic chromatin condensation inducer 1a
chr7_+_33965084 0.62 ENSDART00000052474
timeless interacting protein
chr10_+_35058886 0.62 ENSDART00000145238
exosome component 8
chr12_+_31523411 0.62 ENSDART00000153129
dynamin binding protein
chr3_-_26112995 0.62 ENSDART00000103741
protein phosphatase 4, catalytic subunit a
chr21_-_32747544 0.61

chr11_+_11319810 0.61 ENSDART00000162486
si:dkey-23f9.4
chr21_-_21477462 0.59 ENSDART00000031205
poliovirus receptor-related 3b
chr23_-_31986571 0.59 ENSDART00000135526
mitochondrial fission regulator 2
chr20_+_18360827 0.59 ENSDART00000057039
TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr19_+_43316957 0.59 ENSDART00000151298
cAMP-regulated phosphoprotein, 21
chr2_+_30497691 0.59 ENSDART00000125933
family with sequence similarity 173, member B
chr14_+_24548729 0.59

chr6_+_13676955 0.58 ENSDART00000043522
transmembrane protein 198b
chr24_-_41403824 0.58 ENSDART00000063504
ENSDART00000169374
xylulokinase homolog (H. influenzae)
chr23_-_25208472 0.58 ENSDART00000103989
ENSDART00000160278
isocitrate dehydrogenase 3 (NAD+) gamma
chr12_+_31523147 0.57 ENSDART00000153129
dynamin binding protein
chr14_+_31596468 0.57 ENSDART00000173259
ENSDARG00000100646
chr5_+_62681997 0.56 ENSDART00000137855
si:ch73-376l24.6
chr5_-_12242777 0.56 ENSDART00000137705
leucine-zipper-like transcription regulator 1
chr11_+_29753292 0.56

chr19_+_42657913 0.55 ENSDART00000131574
ENSDART00000135436
jumping translocation breakpoint
chr24_-_36383243 0.55 ENSDART00000155892
si:ch211-40k21.5
chr12_+_30252424 0.55 ENSDART00000153364
si:ch211-225b10.4
chr8_+_24276275 0.55

chr18_-_18886144 0.55 ENSDART00000127182
ADP-ribosylation factor-like 2 binding protein

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 8.1 GO:0060967 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
1.0 3.8 GO:0070986 left/right axis specification(GO:0070986)
0.7 2.9 GO:0039015 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.6 2.5 GO:2000772 regulation of cellular senescence(GO:2000772)
0.5 3.2 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.4 1.2 GO:0051311 meiotic metaphase plate congression(GO:0051311)
0.3 3.2 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.3 0.8 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 1.1 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 0.6 GO:0005997 xylulose metabolic process(GO:0005997)
0.2 0.7 GO:0006407 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
0.2 1.2 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.2 2.5 GO:0050796 regulation of insulin secretion(GO:0050796)
0.2 0.5 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.2 2.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 1.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 0.6 GO:0043111 replication fork arrest(GO:0043111)
0.2 0.6 GO:0071047 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.2 0.8 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 1.5 GO:0048608 gonad development(GO:0008406) reproductive structure development(GO:0048608) reproductive system development(GO:0061458)
0.1 0.7 GO:0010159 specification of organ position(GO:0010159)
0.1 3.3 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 0.4 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 0.9 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.1 1.5 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.4 GO:0032329 serine transport(GO:0032329) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 3.9 GO:0009408 response to heat(GO:0009408)
0.1 2.3 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 0.7 GO:0000730 DNA recombinase assembly(GO:0000730)
0.1 0.8 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 0.7 GO:0035264 multicellular organism growth(GO:0035264)
0.1 3.4 GO:0048264 determination of ventral identity(GO:0048264)
0.1 1.0 GO:1900151 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.1 0.4 GO:0015809 arginine transport(GO:0015809)
0.1 0.7 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.4 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 1.5 GO:0045116 protein neddylation(GO:0045116)
0.1 0.6 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.2 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 0.5 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1 1.7 GO:0000266 mitochondrial fission(GO:0000266)
0.1 2.3 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.1 0.5 GO:0015740 C4-dicarboxylate transport(GO:0015740)
0.1 0.3 GO:1902307 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.4 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.0 0.5 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 1.1 GO:0019827 stem cell population maintenance(GO:0019827)
0.0 0.9 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.2 GO:0071922 regulation of sister chromatid cohesion(GO:0007063) regulation of cohesin loading(GO:0071922)
0.0 0.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.6 GO:0001757 somite specification(GO:0001757)
0.0 0.7 GO:0035803 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 1.1 GO:0007520 myoblast fusion(GO:0007520)
0.0 1.4 GO:1903052 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800) positive regulation of proteolysis involved in cellular protein catabolic process(GO:1903052) positive regulation of cellular protein catabolic process(GO:1903364)
0.0 0.3 GO:0030323 respiratory tube development(GO:0030323) lung development(GO:0030324)
0.0 0.3 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 0.8 GO:0051014 actin filament severing(GO:0051014)
0.0 0.4 GO:0048696 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.3 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 1.0 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.8 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 1.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 2.3 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.5 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.7 GO:0007050 cell cycle arrest(GO:0007050)
0.0 1.3 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.6 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 1.6 GO:0015698 inorganic anion transport(GO:0015698)
0.0 0.2 GO:0006004 fucose metabolic process(GO:0006004)
0.0 1.3 GO:0007281 germ cell development(GO:0007281)
0.0 0.6 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 1.0 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.9 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 1.7 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.8 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.5 GO:0001878 response to yeast(GO:0001878)
0.0 0.6 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.3 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 1.4 GO:0050684 regulation of mRNA processing(GO:0050684) regulation of mRNA metabolic process(GO:1903311)
0.0 0.6 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.6 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.5 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 0.6 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0097189 apoptotic body(GO:0097189)
0.4 1.3 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.3 3.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 2.5 GO:0030667 secretory granule membrane(GO:0030667)
0.2 0.6 GO:0031298 replication fork protection complex(GO:0031298)
0.2 1.4 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 0.8 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 1.0 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 3.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 2.5 GO:0043186 P granule(GO:0043186)
0.1 2.0 GO:0071141 SMAD protein complex(GO:0071141)
0.1 0.5 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.8 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 1.6 GO:0005685 U1 snRNP(GO:0005685)
0.1 1.1 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.3 GO:0071818 BAT3 complex(GO:0071818)
0.1 1.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 1.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 1.2 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 3.1 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.6 GO:0000177 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 1.3 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.9 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.6 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.9 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.7 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 3.2 GO:0030425 dendrite(GO:0030425)
0.0 4.7 GO:0005813 centrosome(GO:0005813)
0.0 1.6 GO:0030027 lamellipodium(GO:0030027)
0.0 2.1 GO:0000786 nucleosome(GO:0000786)
0.0 1.1 GO:0031201 SNARE complex(GO:0031201)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.4 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.0 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 1.1 GO:0005795 Golgi stack(GO:0005795)
0.0 1.3 GO:0005815 microtubule organizing center(GO:0005815)
0.0 0.9 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.6 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 3.8 GO:0005730 nucleolus(GO:0005730)
0.0 0.2 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 1.0 GO:0098791 Golgi subcompartment(GO:0098791)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:1903231 mRNA binding involved in posttranscriptional gene silencing(GO:1903231)
0.7 8.1 GO:0008494 translation activator activity(GO:0008494)
0.4 1.9 GO:0009374 biotin binding(GO:0009374)
0.4 1.5 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.4 1.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.3 2.3 GO:0050699 WW domain binding(GO:0050699)
0.3 0.8 GO:0031730 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729) CCR5 chemokine receptor binding(GO:0031730)
0.3 0.8 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.2 3.2 GO:0019894 kinesin binding(GO:0019894)
0.2 1.3 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.2 2.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.2 1.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 0.9 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.6 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.4 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.1 0.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 1.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.9 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 1.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.5 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 6.8 GO:0003724 RNA helicase activity(GO:0003724)
0.1 1.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 0.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 2.7 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.2 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 1.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 1.5 GO:0031386 protein tag(GO:0031386)
0.1 0.4 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 3.2 GO:0008013 beta-catenin binding(GO:0008013)
0.1 0.3 GO:0017081 chloride channel regulator activity(GO:0017081) chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 0.8 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 2.2 GO:0005178 integrin binding(GO:0005178)
0.1 0.4 GO:0071253 connexin binding(GO:0071253)
0.1 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.4 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.4 GO:0035804 structural constituent of egg coat(GO:0035804)
0.0 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 1.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.6 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.2 GO:0046922 peptide-O-fucosyltransferase activity(GO:0046922)
0.0 0.6 GO:0031267 small GTPase binding(GO:0031267)
0.0 1.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.7 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 1.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.8 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.6 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.8 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 2.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 5.2 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 2.3 GO:0015103 inorganic anion transmembrane transporter activity(GO:0015103)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 1.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 2.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.9 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.6 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 2.5 GO:0019904 protein domain specific binding(GO:0019904)
0.0 1.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 3.2 GO:0042802 identical protein binding(GO:0042802)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.6 GO:0005507 copper ion binding(GO:0005507)
0.0 0.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.7 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.8 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 1.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 0.8 PID ALK2 PATHWAY ALK2 signaling events
0.1 4.4 PID MYC PATHWAY C-MYC pathway
0.1 2.0 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.8 PID P73PATHWAY p73 transcription factor network
0.1 0.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 2.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 3.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.6 PID ATR PATHWAY ATR signaling pathway
0.0 0.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 3.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 0.8 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.9 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 1.0 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.9 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.8 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.1 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.4 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing