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Results for cebpb

Z-value: 1.54

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Transcription factors associated with cebpb

Gene Symbol Gene ID Gene Info
cebpb
ENSDARG00000042725 CCAAT enhancer binding protein beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
cebpbdr10_dc_chr8_-_28415750_284158160.543.2e-02Click!

Activity profile of cebpb motif

Sorted Z-values of cebpb motif

Network of associatons between targets according to the STRING database.

First level regulatory network of cebpb

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr14_-_11765407 7.85 ENSDART00000165581
tmsb1
thymosin beta 1
chr14_+_9115745 5.26 ENSDART00000123652
hmgn6
high mobility group nucleosome binding domain 6
chr5_+_26195540 4.83 ENSDART00000145631
tcn2
transcobalamin II
chr16_-_31670211 4.13 ENSDART00000138216
CR855311.1
ENSDARG00000090352
chr22_-_17570306 3.79 ENSDART00000139361
gpx4a
glutathione peroxidase 4a
chr12_-_5085227 3.76 ENSDART00000160729
rbp4
retinol binding protein 4, plasma
chr15_+_29153215 3.72 ENSDART00000156799
si:ch211-137a8.4
si:ch211-137a8.4
chr19_-_23037220 3.68 ENSDART00000090669
pleca
plectin a
chr24_+_389982 3.46 ENSDART00000061973
tgfbr1b
transforming growth factor, beta receptor 1 b
chr14_+_20809272 3.32 ENSDART00000139865
aldob
aldolase b, fructose-bisphosphate
chr1_+_25662652 3.19 ENSDART00000113020
tet2
tet methylcytosine dioxygenase 2
chr14_-_30363703 3.18 ENSDART00000134098
efemp2a
EGF containing fibulin-like extracellular matrix protein 2a
chr15_-_4322875 3.16 ENSDART00000173311
si:ch211-117a13.2
si:ch211-117a13.2
chr13_-_18506153 3.14 ENSDART00000057869
mat1a
methionine adenosyltransferase I, alpha
chr13_-_39365252 3.14 ENSDART00000019379
marveld1
MARVEL domain containing 1
chr5_+_42930239 3.04 ENSDART00000097618
si:dkey-40c11.2
si:dkey-40c11.2
chr2_+_7917776 2.96 ENSDART00000134178
ENSDART00000130781
eif4a2
eukaryotic translation initiation factor 4A, isoform 2
chr5_+_50432868 2.96 ENSDART00000097466
fam169aa
family with sequence similarity 169, member Aa
chr21_-_39013447 2.95 ENSDART00000114885
aldh3a2b
aldehyde dehydrogenase 3 family, member A2b
chr7_+_63014869 2.92 ENSDART00000161436
pcdh7b
protocadherin 7b
chr11_+_23695123 2.90 ENSDART00000000486
cntn2
contactin 2
chr2_-_30675594 2.89 ENSDART00000087270
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr8_+_15987710 2.88 ENSDART00000165141
elavl4
ELAV like neuron-specific RNA binding protein 4
chr19_-_5781358 2.87 ENSDART00000082050
zgc:174904
zgc:174904
chr1_+_49894978 2.81 ENSDART00000020412
pkd2
polycystic kidney disease 2
chr5_-_43334777 2.80 ENSDART00000142271
ENSDARG00000053091
ENSDARG00000053091
chr5_-_62816208 2.80 ENSDART00000097325
c5
complement component 5
chr16_-_21981065 2.73 ENSDART00000078858
si:ch73-86n18.1
si:ch73-86n18.1
chr25_+_7660590 2.69 ENSDART00000155016
dgkzb
diacylglycerol kinase, zeta b
chr25_+_30746445 2.69 ENSDART00000156916
lsp1
lymphocyte-specific protein 1
chr12_+_25684420 2.64 ENSDART00000024415
epas1a
endothelial PAS domain protein 1a
chr2_+_36634309 2.64 ENSDART00000169547
ENSDART00000098417
pak2a
p21 protein (Cdc42/Rac)-activated kinase 2a
chr7_-_60525749 2.60 ENSDART00000136999
pcxb
pyruvate carboxylase b
chr2_-_28446615 2.57 ENSDART00000179495
cdh6
cadherin 6
chr11_-_42096921 2.51

chr9_+_9524547 2.50 ENSDART00000061525
ENSDART00000125174
nr1i2
nuclear receptor subfamily 1, group I, member 2
chr6_+_42478185 2.49 ENSDART00000150226
mst1ra
macrophage stimulating 1 receptor a
chr9_-_4890648 2.48 ENSDART00000167998
fmnl2a
formin-like 2a
chr18_+_618393 2.47 ENSDART00000159464
nedd4a
neural precursor cell expressed, developmentally down-regulated 4a
chr23_+_45020761 2.47 ENSDART00000159104
atp1b2a
ATPase, Na+/K+ transporting, beta 2a polypeptide
chr23_+_17856053 2.45 ENSDART00000154427
CR381647.1
ENSDARG00000097211
chr17_+_10161999 2.40 ENSDART00000170274
foxa1
forkhead box A1
chr9_+_9524768 2.30 ENSDART00000061525
ENSDART00000125174
nr1i2
nuclear receptor subfamily 1, group I, member 2
chr20_-_47521258 2.28

chr6_+_7283773 2.28 ENSDART00000172285
arf3b
ADP-ribosylation factor 3b
chr9_+_48717490 2.24 ENSDART00000163353
lrp2a
low density lipoprotein receptor-related protein 2a
chr5_+_45822196 2.23

chr10_+_21850059 2.22 ENSDART00000164634
ENSDART00000172513
pcdh1g32
protocadherin 1 gamma 32
chr21_-_15833030 2.21 ENSDART00000080693
lhx5
LIM homeobox 5
chr9_+_219478 2.21 ENSDART00000164048
ENSDART00000161484
ENSDART00000171623
map3k12
mitogen-activated protein kinase kinase kinase 12
chr1_+_25662910 2.14 ENSDART00000113020
tet2
tet methylcytosine dioxygenase 2
chr10_-_23939618 2.11

chr20_+_16843502 2.11 ENSDART00000050308
calm1b
calmodulin 1b
chr12_-_10372055 2.10 ENSDART00000052001
eef2k
eukaryotic elongation factor 2 kinase
chr10_+_39291358 2.09 ENSDART00000159501
stt3a
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr6_-_37444877 2.09 ENSDART00000138351
cth
cystathionase (cystathionine gamma-lyase)
chr12_+_46944395 2.08 ENSDART00000149032
oat
ornithine aminotransferase
chr8_+_7340538 2.06 ENSDART00000121708
pcsk1nl
proprotein convertase subtilisin/kexin type 1 inhibitor, like
chr14_+_36545240 2.02 ENSDART00000032547
lect2l
leukocyte cell-derived chemotaxin 2 like
chr15_+_32853646 2.01 ENSDART00000167515
postnb
periostin, osteoblast specific factor b
chr13_+_28364942 2.00 ENSDART00000025583
fgf8a
fibroblast growth factor 8a
chr7_+_21521123 1.99 ENSDART00000112531
ENSDART00000100936
tmem88b
transmembrane protein 88 b
chr7_-_66229124 1.96 ENSDART00000082604
galnt18b
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18b
chr9_-_35106146 1.96 ENSDART00000139608
ENSDART00000100728
ENSDART00000123005
upf3a
UPF3 regulator of nonsense transcripts homolog A (yeast)
KN150702v1_+_177145 1.92 ENSDART00000166225
CABZ01076674.1
ENSDARG00000102620
chr21_-_4842528 1.92 ENSDART00000097796
rnf165a
ring finger protein 165a
chr9_+_9524688 1.91 ENSDART00000061525
ENSDART00000125174
nr1i2
nuclear receptor subfamily 1, group I, member 2
chr1_-_9387290 1.88 ENSDART00000135522
ENSDART00000135676
fga
fibrinogen alpha chain
chr24_-_32750010 1.88 ENSDART00000038364
ca2
carbonic anhydrase II
chr13_+_28365036 1.81 ENSDART00000025583
fgf8a
fibroblast growth factor 8a
chr5_-_30015572 1.81 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr12_-_10001043 1.81 ENSDART00000152250
ngfrb
nerve growth factor receptor b
chr23_+_35996491 1.79 ENSDART00000127384
hoxc9a
homeobox C9a
chr9_+_3416651 1.77 ENSDART00000019910
dlx1a
distal-less homeobox 1a
chr9_+_23854859 1.76 ENSDART00000060905
gypc
glycophorin C (Gerbich blood group)
chr10_+_39140943 1.72 ENSDART00000158245
si:ch73-1a9.3
si:ch73-1a9.3
chr12_+_35018663 1.72 ENSDART00000085774
si:ch73-127m5.1
si:ch73-127m5.1
chr3_-_11892052 1.68

chr6_+_58549236 1.67 ENSDART00000157018
stmn3
stathmin-like 3
chr3_-_39346621 1.67 ENSDART00000135192
ENSDART00000013553
ENSDART00000167289
zgc:100868
zgc:100868
chr6_+_16279737 1.65 ENSDART00000040035
ccdc80l1
coiled-coil domain containing 80 like 1
KN150339v1_-_34304 1.64

chr5_+_38903966 1.63 ENSDART00000121460
prdm8b
PR domain containing 8b
chr19_+_5073991 1.62 ENSDART00000151050
ENSDARG00000011076
ENSDARG00000011076
chr3_+_23573114 1.61 ENSDART00000024256
hoxb6a
homeobox B6a
chr22_+_15946773 1.60 ENSDART00000144545
rc3h1a
ring finger and CCCH-type domains 1a
chr21_-_9708608 1.59

chr8_-_50159285 1.54 ENSDART00000149010
hp
haptoglobin
chr22_-_23641813 1.54 ENSDART00000159622
cfh
complement factor H
chr4_-_12726432 1.52 ENSDART00000132286
mgst1.2
microsomal glutathione S-transferase 1.2
chr21_-_3301751 1.48 ENSDART00000009740
smad7
SMAD family member 7
chr25_-_1989785 1.48 ENSDART00000156925
wnt7bb
wingless-type MMTV integration site family, member 7Bb
chr3_+_13487523 1.47 ENSDART00000166000
si:ch211-194b1.1
si:ch211-194b1.1
chr17_+_25500291 1.47 ENSDART00000041721
aim1a
crystallin beta-gamma domain containing 1a
chr12_-_36415239 1.45

chr24_-_11103952 1.45

chr10_-_36864268 1.45 ENSDART00000165853
dhrs13a.1
dehydrogenase/reductase (SDR family) member 13a, tandem duplicate 1
chr16_+_21090083 1.44 ENSDART00000052662
hoxa13b
homeobox A13b
chr7_-_25816549 1.43 ENSDART00000052989
ENSDART00000047951
ache
acetylcholinesterase
chr3_-_45420882 1.43 ENSDART00000161507
zgc:153426
zgc:153426
chr21_-_91068 1.42

chr8_+_46378250 1.39 ENSDART00000129661
ENSDART00000084081
ogg1
8-oxoguanine DNA glycosylase
chr18_+_26916897 1.37 ENSDART00000050230
tspan3a
tetraspanin 3a
chr3_-_13942505 1.37

chr8_+_46378706 1.36 ENSDART00000129661
ENSDART00000084081
ogg1
8-oxoguanine DNA glycosylase
chr22_+_16293900 1.36 ENSDART00000164161
osbpl1a
oxysterol binding protein-like 1A
chr23_+_11350727 1.36

chr23_+_25378921 1.34 ENSDART00000143291
RPL41
ribosomal protein L41
chr20_-_52459338 1.34 ENSDART00000135463
rhpn1
rhophilin, Rho GTPase binding protein 1
chr9_+_3416525 1.33 ENSDART00000019910
dlx1a
distal-less homeobox 1a
chr4_+_12618485 1.32 ENSDART00000112860
lmo3
LIM domain only 3
chr22_-_17652938 1.31 ENSDART00000139911
tjp3
tight junction protein 3
chr17_+_52736535 1.28 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr24_-_36840203 1.27 ENSDART00000135142
si:ch73-334d15.1
si:ch73-334d15.1
chr23_+_22729939 1.26 ENSDART00000009337
eno1a
enolase 1a, (alpha)
chr25_-_17142578 1.25 ENSDART00000152106
ccnd2a
cyclin D2, a
chr12_+_25684362 1.23 ENSDART00000024415
epas1a
endothelial PAS domain protein 1a
chr3_+_40667131 1.22 ENSDART00000033713
arpc1b
actin related protein 2/3 complex, subunit 1B
chr6_-_37444807 1.22 ENSDART00000138351
cth
cystathionase (cystathionine gamma-lyase)
chr21_-_8304754 1.22 ENSDART00000055328
nek6
NIMA-related kinase 6
chr19_-_9793494 1.21 ENSDART00000134816
slc2a3a
solute carrier family 2 (facilitated glucose transporter), member 3a
chr9_+_32490721 1.20 ENSDART00000078608
hspe1
heat shock 10 protein 1
chr23_-_19053587 1.19

chr15_-_3120500 1.18

chr2_+_20814888 1.18 ENSDART00000170793
agla
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase a
chr2_+_11245538 1.17 ENSDART00000138737
ENSDART00000081058
acot11a
acyl-CoA thioesterase 11a
chr6_-_14162846 1.17 ENSDART00000100762
inpp4ab
inositol polyphosphate-4-phosphatase type I Ab
chr21_-_11561855 1.16 ENSDART00000162426
cast
calpastatin
chr2_+_27005381 1.16

chr13_-_18064929 1.15 ENSDART00000079902
slc25a16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr6_-_3413472 1.15 ENSDART00000026693
dmbx1b
diencephalon/mesencephalon homeobox 1b
chr17_-_43475725 1.15 ENSDART00000155313
hspa4l
heat shock protein 4 like
chr13_+_40311601 1.14 ENSDART00000148510
got1
glutamic-oxaloacetic transaminase 1, soluble
chr24_-_1308951 1.12

chr21_+_4375508 1.12 ENSDART00000043431
nup188
nucleoporin 188
chr16_-_16793728 1.11 ENSDART00000143550
si:dkey-8k3.2
si:dkey-8k3.2
chr10_-_7427767 1.07 ENSDART00000167963
ENSDART00000162021
nrg1
neuregulin 1
chr11_+_24479085 1.05 ENSDART00000145217
ENSDARG00000070571
ENSDARG00000070571
chr8_-_37011436 1.05 ENSDART00000139567
renbp
renin binding protein
chr17_-_35004687 1.05

chr15_-_17074348 1.03 ENSDART00000156768
hip1
huntingtin interacting protein 1
chr6_-_34237257 1.02 ENSDART00000102391
dmrt2b
doublesex and mab-3 related transcription factor 2b
chr7_+_10346939 1.01

chr25_+_1773157 1.01

chr6_+_54134129 1.01 ENSDART00000156554
hmga1b
high mobility group AT-hook 1b
chr20_-_28739099 1.00 ENSDART00000135513
rgs6
regulator of G protein signaling 6
chr14_-_46646451 0.99

chr23_-_21288972 0.99 ENSDART00000143206
megf6a
multiple EGF-like-domains 6a
chr21_+_18295124 0.99 ENSDART00000167511
ENSDARG00000104101
ENSDARG00000104101
chr17_+_10345498 0.98 ENSDART00000081659
ENSDART00000169120
ENSDART00000170970
ENSDART00000140391
tyro3
TYRO3 protein tyrosine kinase
chr17_+_52736844 0.97 ENSDART00000160507
meis2a
Meis homeobox 2a
chr17_+_11904378 0.97 ENSDART00000150209
ENSDART00000110058
tfb2m
transcription factor B2, mitochondrial
chr21_+_29190291 0.97 ENSDART00000013641
adra1ba
adrenoceptor alpha 1Ba
chr4_-_885413 0.96 ENSDART00000022668
aim1b
crystallin beta-gamma domain containing 1b
chr16_+_33189439 0.96 ENSDART00000101953
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr23_+_2665 0.96 ENSDART00000011146
twist3
twist3
chr4_-_22617898 0.95 ENSDART00000131402
golgb1
golgin B1
chr13_-_45018897 0.94

chr15_-_17074107 0.94 ENSDART00000156768
hip1
huntingtin interacting protein 1
chr5_+_22204129 0.94

chr19_-_46058895 0.94 ENSDART00000163504
trps1
trichorhinophalangeal syndrome I
chr9_-_7260431 0.90 ENSDART00000142726
creg2
cellular repressor of E1A-stimulated genes 2
chr8_+_16954190 0.90 ENSDART00000018934
pde4d
phosphodiesterase 4D, cAMP-specific
chr21_-_11554253 0.90 ENSDART00000133443
cast
calpastatin
chr14_-_46646747 0.89

chr1_-_24486146 0.88 ENSDART00000144711
tmem154
transmembrane protein 154
chr2_+_2295529 0.88 ENSDART00000127286
si:ch73-140j24.4
si:ch73-140j24.4
chr20_+_29307142 0.87 ENSDART00000153016
katnbl1
katanin p80 subunit B-like 1
chr3_+_21928819 0.86 ENSDART00000154622
kansl1b
KAT8 regulatory NSL complex subunit 1b
chr24_-_14432269 0.85 ENSDART00000140624
pabpn1
poly(A) binding protein, nuclear 1
chr7_+_65532871 0.85 ENSDART00000082740
CT573494.2
ENSDARG00000097673
chr9_+_23854967 0.84 ENSDART00000060905
gypc
glycophorin C (Gerbich blood group)
chr10_-_42155708 0.83

chr15_+_24277664 0.83 ENSDART00000155502
sez6b
seizure related 6 homolog b
chr3_+_13040717 0.82

chr4_-_19705018 0.81 ENSDART00000100974
snd1
staphylococcal nuclease and tudor domain containing 1
chr22_+_15412270 0.81 ENSDART00000010846
gpc5b
glypican 5b
chr13_+_41791642 0.77 ENSDART00000114741
polr1b
polymerase (RNA) I polypeptide B
chr9_-_30453625 0.73 ENSDART00000060150
mid1ip1a
MID1 interacting protein 1a
chr14_+_50011198 0.72 ENSDART00000171955
CR855307.1
ENSDARG00000099628
chr10_-_42155790 0.71

chr20_+_29307039 0.69 ENSDART00000152949
katnbl1
katanin p80 subunit B-like 1
chr21_+_4345150 0.69 ENSDART00000025612
phyhd1
phytanoyl-CoA dioxygenase domain containing 1
chr18_-_20880226 0.68 ENSDART00000090079
synm
synemin, intermediate filament protein
chr10_+_45401582 0.68 ENSDART00000159797
zmiz2
zinc finger, MIZ-type containing 2
chr7_-_52692386 0.65 ENSDART00000052029
cart3
cocaine- and amphetamine-regulated transcript 3
chr8_-_46378116 0.64 ENSDART00000136602
qars
glutaminyl-tRNA synthetase
chr6_+_28215039 0.63 ENSDART00000104394
smx5
smx5
chr9_-_34690993 0.62 ENSDART00000114043
ppp2r3b
protein phosphatase 2, regulatory subunit B'', beta
chr22_-_18466781 0.61 ENSDART00000105419
si:ch211-212d10.2
si:ch211-212d10.2
chr14_-_1080574 0.61 ENSDART00000169090
ENSDART00000158905
ENSDART00000159907
ENSDARG00000098694
ENSDARG00000098694
chr9_-_23577201 0.60 ENSDART00000141524
CR392363.2
ENSDARG00000095527
chr17_-_17928974 0.60 ENSDART00000090447
hhipl1
HHIP-like 1
chr11_+_36984616 0.59 ENSDART00000169804
il17rc
interleukin 17 receptor C
chr14_-_46646556 0.59

chr7_-_25816498 0.58 ENSDART00000052989
ENSDART00000047951
ache
acetylcholinesterase
chr23_-_35904414 0.58 ENSDART00000103150
calcoco1a
calcium binding and coiled-coil domain 1a
chr21_+_21706999 0.56 ENSDART00000101700
pold3
polymerase (DNA-directed), delta 3, accessory subunit
chr9_-_34691159 0.55 ENSDART00000114043
ppp2r3b
protein phosphatase 2, regulatory subunit B'', beta
chr24_+_16839260 0.54 ENSDART00000175812
eif2s3
eukaryotic translation initiation factor 2, subunit 3 gamma

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.3 GO:0006211 5-methylcytosine catabolic process(GO:0006211) 5-methylcytosine metabolic process(GO:0019857)
1.0 3.1 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533) regulation of amacrine cell differentiation(GO:1902869) positive regulation of amacrine cell differentiation(GO:1902871)
1.0 3.8 GO:0043586 tongue development(GO:0043586) tongue morphogenesis(GO:0043587) taste bud development(GO:0061193) taste bud morphogenesis(GO:0061194) taste bud formation(GO:0061195)
0.9 2.8 GO:0032965 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246) response to oscillatory fluid shear stress(GO:0097702) cellular response to oscillatory fluid shear stress(GO:0097704)
0.8 5.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.8 3.3 GO:0009092 homoserine metabolic process(GO:0009092) cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) transsulfuration(GO:0019346)
0.8 3.0 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.7 2.9 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.7 2.0 GO:0006581 response to amphetamine(GO:0001975) acetylcholine catabolic process(GO:0006581) response to amine(GO:0014075)
0.6 3.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.6 1.9 GO:0015670 carbon dioxide transport(GO:0015670)
0.5 3.8 GO:0046865 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.4 1.8 GO:1901492 regulation of lymphangiogenesis(GO:1901490) positive regulation of lymphangiogenesis(GO:1901492)
0.4 2.1 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.4 2.5 GO:0098508 endothelial to hematopoietic transition(GO:0098508)
0.4 1.1 GO:0006531 aspartate metabolic process(GO:0006531)
0.4 2.2 GO:0070293 renal absorption(GO:0070293)
0.4 4.8 GO:0051180 vitamin transport(GO:0051180)
0.4 2.9 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.4 1.1 GO:0021755 glial cell migration(GO:0008347) eurydendroid cell differentiation(GO:0021755)
0.3 1.3 GO:0030104 water homeostasis(GO:0030104)
0.3 1.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.3 1.0 GO:0010460 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.3 1.3 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.3 2.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.3 2.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.3 2.7 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.3 3.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 3.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 2.4 GO:0046686 response to cadmium ion(GO:0046686)
0.2 0.6 GO:0070914 UV-damage excision repair(GO:0070914)
0.2 5.1 GO:0009636 response to toxic substance(GO:0009636)
0.2 2.1 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.2 1.9 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.2 2.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 2.4 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.2 1.4 GO:0042574 retinal metabolic process(GO:0042574)
0.2 3.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 2.3 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.2 2.0 GO:0016203 muscle attachment(GO:0016203)
0.1 3.9 GO:0071456 cellular response to hypoxia(GO:0071456)
0.1 2.5 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 2.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 1.2 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 0.5 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.1 1.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.3 GO:0071295 cellular response to nutrient(GO:0031670) vitamin D3 metabolic process(GO:0070640) cellular response to vitamin(GO:0071295) cellular response to vitamin D(GO:0071305)
0.1 0.4 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 1.1 GO:0061074 regulation of neural retina development(GO:0061074)
0.1 1.8 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.1 1.2 GO:0000272 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 3.5 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.1 3.0 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.1 2.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 1.6 GO:0032944 regulation of mononuclear cell proliferation(GO:0032944) regulation of T cell proliferation(GO:0042129) regulation of lymphocyte proliferation(GO:0050670) regulation of leukocyte proliferation(GO:0070663)
0.1 0.7 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 1.9 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 3.1 GO:0042552 myelination(GO:0042552)
0.1 1.4 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 2.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 1.7 GO:0031638 zymogen activation(GO:0031638)
0.1 1.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 5.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.0 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.5 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 3.3 GO:0006979 response to oxidative stress(GO:0006979)
0.0 1.3 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.5 GO:0050994 regulation of lipid catabolic process(GO:0050994)
0.0 1.0 GO:0007548 sex differentiation(GO:0007548)
0.0 1.5 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 1.5 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.4 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 2.0 GO:0032147 activation of protein kinase activity(GO:0032147)
0.0 2.2 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 2.0 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.3 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.4 GO:0033333 fin development(GO:0033333)
0.0 2.2 GO:0030900 forebrain development(GO:0030900)
0.0 0.8 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.2 GO:0003014 renal system process(GO:0003014)
0.0 0.6 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.8 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 0.2 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0005577 fibrinogen complex(GO:0005577)
0.6 3.5 GO:0048179 activin receptor complex(GO:0048179)
0.4 2.0 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.4 1.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.4 2.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.3 3.7 GO:0030056 hemidesmosome(GO:0030056)
0.3 1.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 2.5 GO:0098533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.2 2.3 GO:0009925 basal plasma membrane(GO:0009925)
0.2 0.6 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.6 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 5.6 GO:0030863 cortical cytoskeleton(GO:0030863)
0.1 2.9 GO:0043204 perikaryon(GO:0043204)
0.1 1.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 2.6 GO:0016342 catenin complex(GO:0016342)
0.1 1.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.8 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.9 GO:0044545 NSL complex(GO:0044545)
0.1 2.9 GO:0014069 postsynaptic density(GO:0014069)
0.0 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 25.1 GO:0005615 extracellular space(GO:0005615)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.0 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 8.0 GO:0000785 chromatin(GO:0000785)
0.0 1.3 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.1 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.2 GO:0000502 proteasome complex(GO:0000502)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 2.2 GO:0009986 cell surface(GO:0009986)
0.0 3.4 GO:0005576 extracellular region(GO:0005576)
0.0 0.4 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
1.1 5.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
1.0 3.0 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.9 3.5 GO:0016361 activin receptor activity, type I(GO:0016361)
0.8 3.8 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.8 3.8 GO:0034632 retinol transporter activity(GO:0034632)
0.7 2.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.7 2.1 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.7 2.7 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.7 2.0 GO:0003990 acetylcholinesterase activity(GO:0003990) cholinesterase activity(GO:0004104)
0.6 2.4 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.6 4.8 GO:0031419 cobalamin binding(GO:0031419)
0.6 1.8 GO:0048406 nerve growth factor binding(GO:0048406)
0.5 3.1 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.4 5.1 GO:0003785 actin monomer binding(GO:0003785)
0.4 2.8 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.4 1.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.3 3.7 GO:0030506 ankyrin binding(GO:0030506)
0.3 3.0 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.3 6.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.3 1.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 3.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 1.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.3 1.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.3 2.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.3 2.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.3 0.8 GO:0001054 RNA polymerase I activity(GO:0001054)
0.2 1.0 GO:0004937 alpha-adrenergic receptor activity(GO:0004936) alpha1-adrenergic receptor activity(GO:0004937)
0.2 1.6 GO:0035613 RNA stem-loop binding(GO:0035613)
0.2 1.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 1.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.2 1.0 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 1.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 7.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 2.2 GO:0042562 hormone binding(GO:0042562)
0.1 0.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 2.5 GO:0001671 ATPase activator activity(GO:0001671)
0.1 2.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 2.1 GO:0008483 transaminase activity(GO:0008483)
0.1 0.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 2.0 GO:0030165 PDZ domain binding(GO:0030165)
0.1 1.5 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 5.5 GO:0045296 cadherin binding(GO:0045296)
0.1 2.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.8 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 2.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.5 GO:0034452 dynactin binding(GO:0034452)
0.0 1.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 3.0 GO:0003724 RNA helicase activity(GO:0003724)
0.0 1.5 GO:0005109 frizzled binding(GO:0005109)
0.0 2.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 3.3 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 1.8 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 4.6 GO:0030246 carbohydrate binding(GO:0030246)
0.0 2.4 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 6.7 GO:0051015 actin filament binding(GO:0051015)
0.0 0.6 GO:0034061 DNA-directed DNA polymerase activity(GO:0003887) DNA polymerase activity(GO:0034061)
0.0 0.1 GO:0016803 ether hydrolase activity(GO:0016803)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.7 GO:0051087 chaperone binding(GO:0051087)
0.0 9.2 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.7 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.8 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.4 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.2 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 5.2 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.3 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 2.7 GO:0015631 tubulin binding(GO:0015631)
0.0 0.3 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.4 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 2.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 2.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 2.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 5.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 1.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 1.5 PID ALK1 PATHWAY ALK1 signaling events
0.1 2.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.4 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.8 PID CMYB PATHWAY C-MYB transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.4 1.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 2.7 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.3 6.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.3 2.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.3 3.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.3 2.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 1.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 6.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 3.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 2.0 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 3.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 1.6 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 2.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.4 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 1.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 2.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 0.6 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0 0.9 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.1 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 3.1 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 1.0 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.8 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 2.1 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.3 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 1.0 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription