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Results for clocka+clockb

Z-value: 2.12

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Transcription factors associated with clocka+clockb

Gene Symbol Gene ID Gene Info
ENSDARG00000003631 clock circadian regulator b
ENSDARG00000011703 clock circadian regulator a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
clockbdr10_dc_chr1_+_18739982_18740119-0.629.9e-03Click!

Activity profile of clocka+clockb motif

Sorted Z-values of clocka+clockb motif

Network of associatons between targets according to the STRING database.

First level regulatory network of clocka+clockb

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_+_22065599 8.67 ENSDART00000143461
nucleophosmin 1a (nucleolar phosphoprotein B23, numatrin)
chr12_+_13053552 6.87 ENSDART00000124799
si:ch211-103b1.2
chr5_-_15971338 5.79 ENSDART00000110437
piwi-like RNA-mediated gene silencing 2
chr16_-_34240818 5.64 ENSDART00000054026
regulator of chromosome condensation 1
chr22_-_20670164 4.65 ENSDART00000169077
oogenesis-related gene
chr9_+_25109716 3.95 ENSDART00000037025
solute carrier family 39 (zinc transporter), member 10
chr15_-_17163526 3.80 ENSDART00000101724
v-mos Moloney murine sarcoma viral oncogene homolog
chr13_-_11888944 3.78 ENSDART00000125430
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr18_+_14725283 3.72 ENSDART00000146128
URI1, prefoldin-like chaperone
chr10_+_14984467 3.51

chr22_+_17235696 3.51 ENSDART00000134798
tudor domain containing 5
chr16_-_31834830 3.49

chr15_-_14102102 3.46 ENSDART00000139068
zgc:114130
chr15_+_5125138 3.42 ENSDART00000101937
phosphoglucomutase 2-like 1
chr9_-_11616001 3.37 ENSDART00000030995
uridine monophosphate synthetase
chr5_+_24039736 3.35 ENSDART00000175389
ATPase, H+ transporting, lysosomal V0 subunit a2b
chr13_-_23626146 3.34 ENSDART00000057612
regulator of G protein signaling 17
chr19_+_43984165 3.32 ENSDART00000138404
si:ch211-199g17.2
chr9_+_20970156 3.30 ENSDART00000139174
family with sequence similarity 46, member C
chr25_+_22474794 3.26 ENSDART00000152096
stimulated by retinoic acid 6
chr13_+_35799681 3.21 ENSDART00000046115
major facilitator superfamily domain containing 2aa
chr13_-_11888896 3.20 ENSDART00000125430
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr14_-_21779536 3.15

chr25_+_21001126 3.12 ENSDART00000079012
RAD52 homolog, DNA repair protein
chr16_+_25344257 3.09 ENSDART00000058938
F-box protein 32
chr24_+_36429525 3.08 ENSDART00000062722
pseudouridylate synthase 3
chr20_+_42640466 3.04 ENSDART00000134066
si:dkeyp-93d12.1
chr24_+_34183462 3.02 ENSDART00000143995
zgc:92591
chr3_-_58094618 2.92 ENSDART00000093031
SNU13 homolog, small nuclear ribonucleoprotein a (U4/U6.U5)
chr16_-_21734502 2.91 ENSDART00000179125
ENSDARG00000106589
chr1_+_13768098 2.89 ENSDART00000005067
recombination signal binding protein for immunoglobulin kappa J region a
chr22_+_818795 2.88 ENSDART00000003325
DENN/MADD domain containing 2Db
chr11_+_44678488 2.88 ENSDART00000163408
si:dkey-93h22.8
chr6_+_3556296 2.87 ENSDART00000041627
Sjogren syndrome antigen B (autoantigen La)
chr1_+_5437327 2.84 ENSDART00000092324
ATP-binding cassette, sub-family B (MDR/TAP), member 6a
chr16_-_38383875 2.84 ENSDART00000031895
CDC42 small effector 1
chr5_+_37144525 2.78 ENSDART00000148766
D4, zinc and double PHD fingers family 2
chr7_-_38581532 2.74

chr1_+_49171052 2.74 ENSDART00000164936
lymphoid enhancer-binding factor 1
chr25_-_8548041 2.71 ENSDART00000155280
GDP-D-glucose phosphorylase 1
chr5_-_1604221 2.71 ENSDART00000055878
RNA terminal phosphate cyclase-like 1
chr10_+_22065010 2.71 ENSDART00000133304
nucleophosmin 1a (nucleolar phosphoprotein B23, numatrin)
chr8_+_26040518 2.66 ENSDART00000009178
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr11_-_24300905 2.65 ENSDART00000171004
pleckstrin homology domain containing, family G (with RhoGef domain) member 5a
chr15_+_5124897 2.64 ENSDART00000101937
phosphoglucomutase 2-like 1
chr6_+_50452131 2.64 ENSDART00000155051
myelocytomatosis oncogene homolog
chr9_-_11615763 2.62 ENSDART00000110245
uridine monophosphate synthetase
chr13_+_35799602 2.58 ENSDART00000046115
major facilitator superfamily domain containing 2aa
chr19_-_11097075 2.57 ENSDART00000010997
tropomyosin 3
chr7_-_31346802 2.51 ENSDART00000111388
immunoglobulin superfamily, DCC subclass, member 3
chr4_-_12287171 2.51 ENSDART00000022646
CCR4-NOT transcription complex, subunit 4b
chr5_+_37144384 2.46 ENSDART00000148766
D4, zinc and double PHD fingers family 2
chr16_+_23976353 2.45 ENSDART00000058970
GTP-binding protein 10 (putative)
chr24_+_34183557 2.42 ENSDART00000143995
zgc:92591
chr7_-_41446119 2.42 ENSDART00000099121
ADP-ribosylation factor-like 8
chr10_-_7862983 2.42 ENSDART00000160606
ENSDART00000112201
methionine adenosyltransferase II, alpha a
chr8_-_53165501 2.41 ENSDART00000135982
nuclear receptor subfamily 6, group A, member 1a
chr15_+_5124690 2.40 ENSDART00000101937
phosphoglucomutase 2-like 1
chr10_-_39362315 2.38 ENSDART00000023831
cryptochrome circadian clock 5
chr14_+_15845853 2.38 ENSDART00000160973
polymerase (RNA) I polypeptide A
chr19_+_41834452 2.37 ENSDART00000148732
ENSDART00000149799
distal-less homeobox 6a
chr15_-_33669618 2.34 ENSDART00000161151
StAR-related lipid transfer (START) domain containing 13b
chr7_+_31750808 2.30 ENSDART00000173848
methyltransferase like 15
chr16_-_38383995 2.29 ENSDART00000031895
CDC42 small effector 1
chr8_-_22266041 2.20 ENSDART00000134033
si:ch211-147a11.3
chr6_+_48978653 2.20

chr7_-_41532268 2.20 ENSDART00000016105
ENSDART00000138800
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr5_-_24039681 2.20 ENSDART00000046384
tRNA methyltransferase 2 homolog A
chr14_-_46608307 2.19 ENSDART00000074038
SCY1-like, kinase-like 1
chr8_-_38284748 2.16 ENSDART00000102233
PDZ and LIM domain 2 (mystique)
chr7_-_31346844 2.15 ENSDART00000111388
immunoglobulin superfamily, DCC subclass, member 3
chr8_+_26040405 2.13 ENSDART00000164207
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr13_+_39151166 2.11 ENSDART00000113259
ENSDARG00000079055
chr9_+_21548183 2.10 ENSDART00000059402
N-6 adenine-specific DNA methyltransferase 2 (putative)
KN149704v1_-_17031 2.10

chr3_-_18655432 2.09 ENSDART00000034489
methionine sulfoxide reductase B1a
chr16_-_31834774 2.04

chr18_+_8959686 2.04 ENSDART00000145226
si:ch211-233h19.2
chr5_+_12336846 2.04 ENSDART00000023101
pescadillo
chr5_-_45358634 2.04 ENSDART00000135072
POC5 centriolar protein homolog (Chlamydomonas)
chr7_+_31750775 2.02 ENSDART00000173848
methyltransferase like 15
chr24_+_39631194 2.02 ENSDART00000013894
defective in cullin neddylation 1 domain containing 3
chr5_-_11162837 2.01

chr7_+_41532360 2.00 ENSDART00000174333
origin recognition complex, subunit 6
chr9_+_27909662 1.99 ENSDART00000112415
leucine carboxyl methyltransferase 2
chr14_-_44844086 1.98 ENSDART00000159988
family with sequence similarity 193, member B
chr20_+_2625716 1.97 ENSDART00000058775
zgc:101562
chr24_-_38757042 1.96 ENSDART00000170194
solute carrier family 6, member 16b
chr14_+_21779325 1.93 ENSDART00000106147
solute carrier family 43 (amino acid system L transporter), member 1a
chr7_+_29931094 1.93 ENSDART00000173525
WD repeat domain 76
chr19_+_39689450 1.92

chr25_-_8548210 1.90 ENSDART00000155280
GDP-D-glucose phosphorylase 1
chr6_-_22060441 1.90 ENSDART00000167167
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr5_+_36168475 1.89 ENSDART00000146854
MAP/microtubule affinity-regulating kinase 4a
chr14_-_35932521 1.88 ENSDART00000158722
ENSDARG00000101064
chr19_+_24741351 1.85 ENSDART00000090081
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Ab
chr12_-_4596004 1.85 ENSDART00000160617
proline rich 12a
chr13_-_23626319 1.84 ENSDART00000124152
regulator of G protein signaling 17
chr8_-_38284904 1.83 ENSDART00000125920
PDZ and LIM domain 2 (mystique)
chr9_-_30174641 1.82 ENSDART00000134157
ENSDART00000089206
interleukin 1 receptor accessory protein-like 1a
chr9_+_21548069 1.79 ENSDART00000147619
N-6 adenine-specific DNA methyltransferase 2 (putative)
chr24_-_21788942 1.78 ENSDART00000113092
abhydrolase domain containing 10b
chr18_+_27457678 1.76 ENSDART00000014726
tumor protein p53 inducible protein 11b
chr5_-_31738565 1.76 ENSDART00000017956
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr4_-_13025193 1.76 ENSDART00000177894
ENSDARG00000106390
chr7_+_28782077 1.75 ENSDART00000134332
family with sequence similarity 60, member A, like
chr23_+_38335290 1.74 ENSDART00000177981
ENSDART00000178842
ENSDARG00000109193
chr13_+_35799851 1.74 ENSDART00000046115
major facilitator superfamily domain containing 2aa
chr25_-_8548430 1.73 ENSDART00000155280
GDP-D-glucose phosphorylase 1
chr7_-_41446221 1.73 ENSDART00000099121
ADP-ribosylation factor-like 8
chr5_+_69178270 1.73 ENSDART00000097359
DnaJ (Hsp40) homolog, subfamily C , member 25
chr9_+_21548044 1.73 ENSDART00000147619
N-6 adenine-specific DNA methyltransferase 2 (putative)
chr14_+_15845943 1.73 ENSDART00000159352
polymerase (RNA) I polypeptide A
chr20_+_27088328 1.73 ENSDART00000012816
sel-1 suppressor of lin-12-like (C. elegans)
chr19_-_34529880 1.72 ENSDART00000158677
ENSDART00000112004
si:dkey-184p18.2
chr25_-_7539433 1.72 ENSDART00000131415
cAMP-regulated phosphoprotein 19b
chr5_-_27394361 1.72 ENSDART00000132740
protein phosphatase 3, catalytic subunit, gamma isozyme, a
chr13_-_4863766 1.71 ENSDART00000159679
nucleolar and coiled-body phosphoprotein 1
chr21_-_11877525 1.71 ENSDART00000145194
NOP56 ribonucleoprotein homolog
chr15_+_40228382 1.70

chr12_-_21562929 1.70 ENSDART00000152999
essential meiotic structure-specific endonuclease 1
chr15_-_33669589 1.69 ENSDART00000161151
StAR-related lipid transfer (START) domain containing 13b
chr19_-_3849836 1.68 ENSDART00000172415
bloodthirsty-related gene family, member 18
chr17_+_23534953 1.68 ENSDART00000135814
pantothenate kinase 1a
chr19_-_24971920 1.68 ENSDART00000132660
polymerase (RNA) III (DNA directed) polypeptide G like a
chr13_-_2296041 1.68 ENSDART00000126697
glutamate-cysteine ligase, catalytic subunit
chr18_-_20476969 1.67 ENSDART00000060311
progestin and adipoQ receptor family member Va
chr7_+_14290727 1.67 ENSDART00000027331
mitochondrial ribosomal protein L46
chr1_-_25982625 1.65 ENSDART00000152492
tRNA methyltransferase O
chr20_-_46079578 1.64 ENSDART00000153228
ENSDARG00000096676
chr5_-_12592887 1.64

chr5_-_47609309 1.63

chr1_-_53021646 1.63

chr17_-_7661725 1.63 ENSDART00000143870
required for meiotic nuclear division 1 homolog
chr22_-_10562118 1.62 ENSDART00000105846
si:dkey-42i9.8
chr4_-_17654047 1.62

chr20_+_25726978 1.62 ENSDART00000164264
phosphoribosyl pyrophosphate amidotransferase
chr21_-_44086464 1.61 ENSDART00000130833
ENSDARG00000087492
chr22_-_36721626 1.61 ENSDART00000017188
ENSDART00000124698
nucleolin
chr3_+_31530419 1.61 ENSDART00000113441
myosin, light chain kinase 5
chr20_+_38354928 1.60 ENSDART00000149160
chemokine (C-C motif) ligand 38, duplicate 6
chr2_+_19588034 1.60 ENSDART00000163875
coiled-coil and C2 domain containing 1B
chr13_-_11888864 1.59 ENSDART00000125430
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr19_+_43523515 1.58 ENSDART00000023156
ENSDART00000039129
eukaryotic translation elongation factor 1 alpha 1, like 2
chr5_-_18561185 1.58

chr12_+_18776712 1.55

chr4_-_1496779 1.54 ENSDART00000166360
nucleosome assembly protein 1-like 1
chr3_+_54551887 1.53 ENSDART00000169663
ENSDARG00000098327
chr20_-_3292418 1.53 ENSDART00000099315
CCAAT/enhancer binding protein (C/EBP), zeta
chr21_-_22085596 1.53 ENSDART00000101726
solute carrier family 35, member F2
chr10_-_7862767 1.52 ENSDART00000059021
methionine adenosyltransferase II, alpha a
chr24_+_39630741 1.51 ENSDART00000132939
defective in cullin neddylation 1 domain containing 3
chr11_-_24300849 1.51 ENSDART00000171004
pleckstrin homology domain containing, family G (with RhoGef domain) member 5a
chr15_+_40228295 1.51 ENSDART00000111018
neuronal guanine nucleotide exchange factor
chr11_+_3939876 1.49 ENSDART00000122953
guanine nucleotide binding protein-like 3 (nucleolar)
chr1_-_42915971 1.49

chr15_+_5124820 1.48 ENSDART00000101937
phosphoglucomutase 2-like 1
chr1_+_5437488 1.48 ENSDART00000092324
ATP-binding cassette, sub-family B (MDR/TAP), member 6a
chr24_-_38757086 1.48 ENSDART00000170194
solute carrier family 6, member 16b
chr5_+_68036497 1.48 ENSDART00000017849
hairy and enhancer of split related-7
chr5_-_47609402 1.47

chr8_-_38284959 1.47 ENSDART00000125920
PDZ and LIM domain 2 (mystique)
chr10_-_15382145 1.47 ENSDART00000133919
pumilio RNA-binding family member 3
chr16_-_42015364 1.47 ENSDART00000136742
ENSDARG00000091933
chr4_+_17653739 1.46 ENSDART00000026509
CWF19-like 1, cell cycle control
chr13_+_6060281 1.46 ENSDART00000161062
ENSDART00000109665
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr19_-_2084484 1.45

chr2_+_10192670 1.44 ENSDART00000011906
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr13_+_39151116 1.44 ENSDART00000113259
ENSDARG00000079055
chr22_-_36721592 1.43 ENSDART00000130171
nucleolin
chr5_+_12336706 1.43 ENSDART00000023101
pescadillo
chr4_-_7721419 1.43

chr4_-_14193396 1.43 ENSDART00000101812
ENSDART00000143804
pseudouridylate synthase 7-like
chr3_-_35734943 1.42 ENSDART00000135957
SUZ12 polycomb repressive complex 2a subunit
chr19_+_42758938 1.42 ENSDART00000077059
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr25_+_21001338 1.41 ENSDART00000017488
RAD52 homolog, DNA repair protein
chr1_-_19071020 1.41 ENSDART00000005733
translation machinery associated 16 homolog
chr24_+_36430199 1.40

chr3_-_56803756 1.40 ENSDART00000014103
zgc:112148
chr17_-_29196678 1.40 ENSDART00000076481
EH-domain containing 4
chr18_+_6339577 1.40 ENSDART00000136333
WAS protein family homolog 1
chr20_-_53123015 1.39 ENSDART00000162812
farnesyl-diphosphate farnesyltransferase 1
chr12_-_5153412 1.39 ENSDART00000160037
FRA10A associated CGG repeat 1
chr23_+_37124543 1.39 ENSDART00000155706
ENSDARG00000097111
chr8_-_22267016 1.39 ENSDART00000140978
si:ch211-147a11.3
chr25_+_18997440 1.39 ENSDART00000155569
si:dkeyp-19h3.8
chr23_-_21607742 1.39 ENSDART00000139092
regulator of chromosome condensation 2
chr8_-_22266750 1.39 ENSDART00000100042
ENSDART00000138966
si:ch211-147a11.3
chr20_-_22299344 1.38 ENSDART00000063578
steroid 5 alpha-reductase 3
chr6_-_22059932 1.38 ENSDART00000162148
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr8_+_31019730 1.38

chr3_-_5523147 1.38 ENSDART00000159308
tripartite motif containing 35-7
chr6_+_58528496 1.38 ENSDART00000157327
ADP-ribosylation factor related protein 1
chr8_+_29885318 1.37 ENSDART00000154309
ENSDARG00000097806
chr25_+_21001016 1.37 ENSDART00000079012
RAD52 homolog, DNA repair protein
chr19_-_2222108 1.37 ENSDART00000127578
TWIST neighbor
chr16_-_13723778 1.36 ENSDART00000139102
D site albumin promoter binding protein b
chr13_+_8560739 1.36 ENSDART00000075054
thyroid adenoma associated
chr24_-_6647047 1.36

chr3_+_7877162 1.36 ENSDART00000057434
ENSDART00000170291
hook microtubule-tethering protein 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 12.1 GO:0051029 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
1.9 5.8 GO:1990511 piRNA biosynthetic process(GO:1990511)
1.9 7.5 GO:1990379 maintenance of blood-brain barrier(GO:0035633) lysophospholipid transport(GO:0051977) lipid transport across blood brain barrier(GO:1990379)
1.2 6.0 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
1.1 4.4 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
1.1 4.3 GO:0061072 iris morphogenesis(GO:0061072)
0.9 5.6 GO:0045002 DNA recombinase assembly(GO:0000730) double-strand break repair via single-strand annealing(GO:0045002)
0.9 4.4 GO:1901993 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.8 3.2 GO:0036049 regulation of ketone biosynthetic process(GO:0010566) protein demalonylation(GO:0036046) peptidyl-lysine demalonylation(GO:0036047) protein desuccinylation(GO:0036048) peptidyl-lysine desuccinylation(GO:0036049) protein deglutarylation(GO:0061698)
0.8 3.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.8 8.5 GO:0009303 rRNA transcription(GO:0009303)
0.7 2.9 GO:0072314 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.7 2.9 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.7 5.3 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.6 1.9 GO:0050857 regulation of antigen receptor-mediated signaling pathway(GO:0050854) regulation of B cell receptor signaling pathway(GO:0050855) positive regulation of antigen receptor-mediated signaling pathway(GO:0050857) positive regulation of B cell receptor signaling pathway(GO:0050861)
0.6 5.5 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.6 1.8 GO:2000725 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.5 3.2 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.5 3.0 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.5 3.3 GO:0071939 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.5 2.7 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.4 4.8 GO:0046037 GMP biosynthetic process(GO:0006177) GTP biosynthetic process(GO:0006183) GMP metabolic process(GO:0046037)
0.4 5.6 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.4 2.1 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.4 1.3 GO:0006683 galactosylceramide catabolic process(GO:0006683) galactolipid catabolic process(GO:0019376)
0.4 0.8 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.4 4.6 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.4 1.2 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.4 0.4 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.4 4.7 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.4 5.0 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.3 1.0 GO:0070914 UV-damage excision repair(GO:0070914)
0.3 1.4 GO:0019408 dolichol biosynthetic process(GO:0019408)
0.3 1.0 GO:0046887 positive regulation of peptide secretion(GO:0002793) positive regulation of insulin secretion(GO:0032024) positive regulation of hormone secretion(GO:0046887) positive regulation of peptide hormone secretion(GO:0090277)
0.3 4.0 GO:0018298 protein-chromophore linkage(GO:0018298)
0.3 1.6 GO:0071346 monocyte chemotaxis(GO:0002548) response to interferon-gamma(GO:0034341) cellular response to interferon-gamma(GO:0071346)
0.3 1.9 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
0.3 0.9 GO:0010259 multicellular organism aging(GO:0010259)
0.3 1.1 GO:0019852 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.3 1.1 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.3 0.8 GO:0051096 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.3 4.4 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.3 0.8 GO:0071028 U4 snRNA 3'-end processing(GO:0034475) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.2 6.5 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.2 3.5 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.2 1.8 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.2 11.5 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.2 0.7 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.2 10.3 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.2 3.5 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.2 1.2 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.2 0.6 GO:0006014 D-ribose metabolic process(GO:0006014)
0.2 1.4 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.2 1.0 GO:0034367 macromolecular complex remodeling(GO:0034367)
0.2 1.0 GO:0051657 maintenance of organelle location(GO:0051657)
0.2 6.0 GO:0030488 tRNA methylation(GO:0030488)
0.2 3.7 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.2 6.6 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.2 0.7 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.2 1.7 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.2 6.3 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.2 2.5 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.2 2.2 GO:0070475 rRNA base methylation(GO:0070475)
0.2 1.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.2 2.4 GO:0035141 medial fin morphogenesis(GO:0035141)
0.2 1.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 1.2 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.1 0.9 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.1 0.6 GO:0019856 pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1 0.9 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 0.4 GO:0002188 translation reinitiation(GO:0002188)
0.1 2.0 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.7 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.1 0.8 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 1.4 GO:0001522 pseudouridine synthesis(GO:0001522)
0.1 0.8 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.8 GO:0007260 tyrosine phosphorylation of STAT protein(GO:0007260) regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1 0.4 GO:0045943 regulation of transcription from RNA polymerase I promoter(GO:0006356) positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 1.4 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 0.3 GO:0003091 renal water homeostasis(GO:0003091) renal water transport(GO:0003097) hyaluronan biosynthetic process(GO:0030213) extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 2.8 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.9 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 2.6 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 3.2 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 1.5 GO:0001757 somite specification(GO:0001757)
0.1 1.4 GO:0006265 DNA topological change(GO:0006265)
0.1 1.9 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1 0.4 GO:0043650 dicarboxylic acid biosynthetic process(GO:0043650)
0.1 3.6 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 1.2 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 1.7 GO:0007632 visual behavior(GO:0007632)
0.1 1.4 GO:0043486 histone exchange(GO:0043486)
0.1 1.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.5 GO:0008354 germ cell migration(GO:0008354)
0.1 0.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.9 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 1.9 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.1 0.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.3 GO:0018201 peptidyl-glycine modification(GO:0018201)
0.1 0.8 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.4 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 1.8 GO:0001878 response to yeast(GO:0001878)
0.0 1.2 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0070084 protein initiator methionine removal(GO:0070084)
0.0 0.5 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 1.4 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.7 GO:0070661 mononuclear cell proliferation(GO:0032943) T cell proliferation(GO:0042098) lymphocyte proliferation(GO:0046651) leukocyte proliferation(GO:0070661)
0.0 0.9 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 2.2 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 3.8 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 1.2 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 2.1 GO:0009306 protein secretion(GO:0009306)
0.0 0.6 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.0 0.7 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 1.3 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 1.0 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 1.7 GO:0051028 mRNA transport(GO:0051028)
0.0 2.4 GO:0045087 innate immune response(GO:0045087)
0.0 0.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 1.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.9 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.5 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 1.8 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 1.1 GO:0048477 female gamete generation(GO:0007292) oogenesis(GO:0048477)
0.0 0.7 GO:0000077 DNA damage checkpoint(GO:0000077)
0.0 0.8 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.4 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.2 GO:0006555 methionine metabolic process(GO:0006555) methionine biosynthetic process(GO:0009086)
0.0 0.7 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.1 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.8 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.8 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.4 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0032324 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.6 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 1.2 GO:0070646 protein modification by small protein removal(GO:0070646)
0.0 0.2 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.2 GO:0010212 response to ionizing radiation(GO:0010212)
0.0 0.6 GO:0006821 chloride transport(GO:0006821)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 10.1 GO:0071546 pi-body(GO:0071546)
0.9 3.5 GO:0070545 PeBoW complex(GO:0070545)
0.7 2.0 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.7 4.7 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.7 3.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.6 3.2 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.6 3.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.6 5.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.6 4.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.6 1.7 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.4 3.0 GO:0005955 calcineurin complex(GO:0005955)
0.4 2.0 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.4 2.7 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.3 5.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.3 0.8 GO:0070390 transcription export complex 2(GO:0070390)
0.2 0.6 GO:0034457 Mpp10 complex(GO:0034457)
0.2 6.7 GO:0031941 filamentous actin(GO:0031941)
0.2 2.2 GO:0030904 retromer complex(GO:0030904)
0.2 1.0 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.2 2.7 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 2.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 1.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 2.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 7.7 GO:0030139 endocytic vesicle(GO:0030139)
0.1 3.7 GO:0071565 nBAF complex(GO:0071565)
0.1 1.4 GO:0000812 Swr1 complex(GO:0000812)
0.1 31.8 GO:0005730 nucleolus(GO:0005730)
0.1 2.0 GO:0071141 SMAD protein complex(GO:0071141)
0.1 1.2 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 1.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.7 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 1.5 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 0.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 2.1 GO:0030286 dynein complex(GO:0030286)
0.1 0.5 GO:0070187 telosome(GO:0070187)
0.1 1.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 2.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 6.7 GO:0000786 nucleosome(GO:0000786)
0.1 0.8 GO:0000813 ESCRT I complex(GO:0000813)
0.1 5.3 GO:0005802 trans-Golgi network(GO:0005802)
0.1 0.7 GO:0000124 SAGA complex(GO:0000124)
0.0 0.7 GO:0043186 P granule(GO:0043186)
0.0 1.3 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.8 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.9 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.4 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 1.9 GO:0005884 actin filament(GO:0005884)
0.0 0.5 GO:0097346 INO80-type complex(GO:0097346)
0.0 0.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 1.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 2.0 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.3 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.1 GO:0098845 postsynaptic recycling endosome(GO:0098837) postsynaptic endosome(GO:0098845)
0.0 0.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 4.3 GO:0005774 vacuolar membrane(GO:0005774)
0.0 0.7 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 9.3 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.7 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.6 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.8 GO:0000151 ubiquitin ligase complex(GO:0000151)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.5 GO:0051978 lysophospholipid transporter activity(GO:0051978)
1.5 4.6 GO:0071424 rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424)
1.4 5.8 GO:0034584 piRNA binding(GO:0034584)
1.1 3.2 GO:0016595 glutamate-cysteine ligase activity(GO:0004357) glutamate binding(GO:0016595)
0.9 4.3 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.8 4.9 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.8 3.2 GO:0036055 protein-malonyllysine demalonylase activity(GO:0036054) protein-succinyllysine desuccinylase activity(GO:0036055) protein-glutaryllysine deglutarylase activity(GO:0061697)
0.8 4.8 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.8 4.7 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.7 2.1 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.7 3.3 GO:0034632 retinol transporter activity(GO:0034632)
0.6 1.9 GO:0004044 amidophosphoribosyltransferase activity(GO:0004044)
0.6 1.8 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.5 1.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.5 9.6 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.5 11.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.5 1.4 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.5 4.6 GO:0051117 ATPase binding(GO:0051117)
0.5 1.4 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.4 3.0 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.4 5.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.4 1.3 GO:0004336 galactosylceramidase activity(GO:0004336)
0.4 1.2 GO:0004482 mRNA (guanine-N7-)-methyltransferase activity(GO:0004482)
0.4 1.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.4 1.6 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.3 6.7 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.3 0.9 GO:0034417 bisphosphoglycerate 3-phosphatase activity(GO:0034417)
0.3 0.9 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.2 3.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.2 0.9 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.2 1.8 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 3.7 GO:0008301 DNA binding, bending(GO:0008301)
0.2 3.5 GO:0097602 cullin family protein binding(GO:0097602)
0.2 1.2 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 4.3 GO:0030515 snoRNA binding(GO:0030515)
0.2 2.9 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.2 1.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 0.5 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.2 1.4 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.2 6.2 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.2 7.9 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.2 0.6 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.1 1.4 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 4.3 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.1 1.4 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.1 1.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.7 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.1 1.0 GO:0035198 miRNA binding(GO:0035198)
0.1 0.6 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.8 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.5 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 2.6 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.1 16.7 GO:0042393 histone binding(GO:0042393)
0.1 1.2 GO:1990782 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.1 0.2 GO:0000403 Y-form DNA binding(GO:0000403)
0.1 1.1 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 4.1 GO:0004521 endoribonuclease activity(GO:0004521)
0.1 0.8 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 4.5 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.1 13.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 0.8 GO:0035591 signaling adaptor activity(GO:0035591)
0.1 5.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.9 GO:0071949 FAD binding(GO:0071949)
0.1 3.6 GO:0003724 RNA helicase activity(GO:0003724)
0.1 0.3 GO:0051920 peroxiredoxin activity(GO:0051920)
0.1 2.5 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.6 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.2 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.7 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 1.7 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 0.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 7.0 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 5.0 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 1.7 GO:0005496 steroid binding(GO:0005496)
0.0 1.0 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 2.1 GO:0004518 nuclease activity(GO:0004518)
0.0 4.6 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 1.5 GO:0008047 enzyme activator activity(GO:0008047)
0.0 0.0 GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0 0.1 GO:0005035 death receptor activity(GO:0005035)
0.0 0.2 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.2 9.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 2.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 5.0 PID FOXO PATHWAY FoxO family signaling
0.1 1.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 1.2 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 1.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 0.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.7 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 0.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 2.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 0.9 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.0 PID ATM PATHWAY ATM pathway
0.0 0.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 2.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.0 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.3 6.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.3 1.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 3.7 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 1.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.2 3.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 2.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.2 5.1 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.2 4.6 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.2 1.4 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 1.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 10.3 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.1 1.2 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1 2.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.9 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 2.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 0.7 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.6 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 1.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.1 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.2 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.8 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription