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DANIO-CODE

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Results for creb1a+creb1b

Z-value: 5.52

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Transcription factors associated with creb1a+creb1b

Gene Symbol Gene ID Gene Info
creb1a
ENSDARG00000053586 cAMP responsive element binding protein 1a
creb1b
ENSDARG00000093420 cAMP responsive element binding protein 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
creb1adr10_dc_chr1_-_32825385_328254330.467.1e-02Click!
creb1bdr10_dc_chr9_-_28464146_28464209-0.214.4e-01Click!

Activity profile of creb1a+creb1b motif

Sorted Z-values of creb1a+creb1b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of creb1a+creb1b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_+_28429523 7.54 ENSDART00000111603
znf1041
zinc finger protein 1041
chr4_+_51798289 6.72

chr4_+_46096104 6.21

chr4_-_71302151 5.92

chr4_-_44665935 5.92 ENSDART00000150524
si:ch211-162i8.4
si:ch211-162i8.4
chr4_+_30499948 5.89 ENSDART00000164555
si:dkey-199m13.4
si:dkey-199m13.4
KN149695v1_-_61011 5.86 ENSDART00000160846
BX510909.1
ENSDARG00000098877
chr4_+_50303963 5.84 ENSDART00000170022
zgc:173705
zgc:173705
chr4_-_32820181 5.66

chr4_+_40119702 5.53

chr4_+_43151489 5.51 ENSDART00000166967
si:ch211-226o13.2
si:ch211-226o13.2
chr7_-_73620443 5.36 ENSDART00000158891
ENSDART00000111622
FP236812.3
ENSDARG00000079652
chr4_-_29003925 5.35 ENSDART00000111294
zgc:174315
zgc:174315
chr4_-_29059042 5.31 ENSDART00000169971
CR387997.1
ENSDARG00000099486
chr4_+_67053031 5.20 ENSDART00000158019
CR759907.2
ENSDARG00000099855
chr4_+_43810061 5.10 ENSDART00000157214
si:dkey-7j22.2
si:dkey-7j22.2
chr4_-_35766769 5.03 ENSDART00000163144
zgc:174653
zgc:174653
chr4_+_50923792 4.99 ENSDART00000161370
BX640547.3
ENSDARG00000100076
chr4_-_71278793 4.98 ENSDART00000159715
CABZ01021453.1
ENSDARG00000102090
chr4_+_29842350 4.92

chr4_-_46819684 4.83

chr2_+_21947475 4.82 ENSDART00000112014
mplkip
M-phase specific PLK1 interacting protein
chr4_+_57648974 4.58 ENSDART00000108499
znf1068
zinc finger protein 1068
chr4_+_46379457 4.49 ENSDART00000162948
BX324155.1
ENSDARG00000104638
chr4_-_52850069 4.46 ENSDART00000169714
CR388413.6
ENSDARG00000108204
chr4_-_30634885 4.43 ENSDART00000178931
CABZ01008480.1
ENSDARG00000103047
KN149990v1_-_3473 4.42 ENSDART00000175421
CABZ01024854.1
ENSDARG00000109161
chr4_-_33436230 4.42 ENSDART00000150319
znf1000
zinc finger protein 1000
chr19_+_27338879 4.41 ENSDART00000149988
nelfe
negative elongation factor complex member E
chr4_-_44105748 4.39 ENSDART00000150621
znf1137
zinc finger protein 1137
chr15_+_895792 4.32

chr15_+_943216 4.27 ENSDART00000155783
si:dkey-77f5.13
si:dkey-77f5.13
chr4_+_38593055 4.23 ENSDART00000150397
znf977
zinc finger protein 977
chr4_+_74835204 4.17 ENSDART00000172647
ENSDART00000174351
zgc:113209
zgc:113209
chr4_-_51772774 4.10

chr4_+_58242614 4.10

chr4_+_29817277 4.10 ENSDART00000167186
BX323023.2
ENSDARG00000104750
chr4_+_28860191 3.99 ENSDART00000110358
ENSDART00000162069
znf1059
zinc finger protein 1059
chr4_-_39822997 3.94 ENSDART00000151957
si:dkey-22h13.2
si:dkey-22h13.2
chr15_+_880573 3.85 ENSDART00000115077
zgc:174573
zgc:174573
chr4_+_45007600 3.79

chr4_-_46037928 3.76

chr4_-_72603830 3.71 ENSDART00000168547
si:cabz01071912.2
si:cabz01071912.2
chr4_+_29577554 3.66

KN149696v1_+_361745 3.65 ENSDART00000159019
CABZ01074982.1
ENSDARG00000099884
chr4_-_71856428 3.61 ENSDART00000158977
si:ch73-266f23.1
si:ch73-266f23.1
chr4_+_63623569 3.61 ENSDART00000170824
znf1108
zinc finger protein 1108
chr19_+_3115791 3.60 ENSDART00000127473
ENSDART00000126549
ENSDART00000024593
ENSDART00000082353
ENSDART00000141324
hsf1
heat shock transcription factor 1
chr4_+_29008199 3.59 ENSDART00000150629
si:dkey-23a23.3
si:dkey-23a23.3
chr4_+_29008115 3.58 ENSDART00000150629
si:dkey-23a23.3
si:dkey-23a23.3
chr4_-_72008515 3.57 ENSDART00000150704
si:ch73-266f23.3
si:ch73-266f23.3
chr4_+_59415357 3.57 ENSDART00000177097
BX255935.3
ENSDARG00000106194
chr4_+_41633430 3.55 ENSDART00000162193
si:ch211-142b24.2
si:ch211-142b24.2
chr4_-_64349492 3.55

chr4_-_71730637 3.53 ENSDART00000174367
CABZ01032472.1
ENSDARG00000105801
chr4_-_57935184 3.52

chr4_-_29350215 3.50 ENSDART00000169882
CR847895.3
ENSDARG00000101105
chr4_-_48486361 3.50 ENSDART00000150854
znf1135
zinc finger protein 1135
chr19_+_3115685 3.41 ENSDART00000127473
ENSDART00000126549
ENSDART00000024593
ENSDART00000082353
ENSDART00000141324
hsf1
heat shock transcription factor 1
chr17_-_49381216 3.40 ENSDART00000166394
fcf1
FCF1 rRNA-processing protein
chr4_-_60987404 3.38

chr4_+_44111085 3.37 ENSDART00000169784
znf980
zinc finger protein 980
chr4_+_64539374 3.32 ENSDART00000170893
znf1070
zinc finger protein 1070
chr4_+_29775735 3.31 ENSDART00000166510
BX530097.1
ENSDARG00000104762
chr22_-_9879639 3.30

chr4_-_29488075 3.28 ENSDART00000167636
CR847895.4
ENSDARG00000101492
chr7_-_68962286 3.25

chr4_+_62868377 3.21 ENSDART00000159754
si:ch211-223a21.4
si:ch211-223a21.4
chr4_-_59767735 3.20 ENSDART00000159114
znf1129
zinc finger protein 1129
chr14_-_8749933 3.20 ENSDART00000041099
ENSDART00000138758
sybl1
synaptobrevin-like 1
chr19_+_3115642 3.19 ENSDART00000127473
ENSDART00000126549
ENSDART00000024593
ENSDART00000082353
ENSDART00000141324
hsf1
heat shock transcription factor 1
chr4_-_71367238 3.17 ENSDART00000165327
CABZ01021450.2
ENSDARG00000100390
chr4_+_75262389 3.16 ENSDART00000174100
CABZ01015815.2
ENSDARG00000105672
chr4_+_74885660 3.14 ENSDART00000164709
zgc:153116
zgc:153116
chr4_+_4825461 3.13 ENSDART00000150309
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr17_+_12853175 3.11 ENSDART00000064554
ppp2r3c
protein phosphatase 2, regulatory subunit B'', gamma
chr4_+_29855479 3.04

chr4_+_36226349 2.97

chr1_+_18390488 2.95 ENSDART00000002886
ENSDART00000158745
exosc9
exosome component 9
chr4_+_59014576 2.95

chr10_+_28420109 2.91 ENSDART00000142016
ptrh2
peptidyl-tRNA hydrolase 2
chr19_+_3115514 2.90 ENSDART00000127473
ENSDART00000126549
ENSDART00000024593
ENSDART00000082353
ENSDART00000141324
hsf1
heat shock transcription factor 1
chr15_-_743589 2.90 ENSDART00000156200
zgc:174574
zgc:174574
chr15_+_935686 2.90

chr6_+_3556296 2.89 ENSDART00000041627
ssb
Sjogren syndrome antigen B (autoantigen La)
chr4_+_67334424 2.87 ENSDART00000136092
si:ch211-209j12.3
si:ch211-209j12.3
chr4_+_56350528 2.87 ENSDART00000167976
BX927290.1
ENSDARG00000098469
chr4_-_25526284 2.86 ENSDART00000142276
rbm17
RNA binding motif protein 17
chr4_+_28429480 2.85 ENSDART00000162648
znf1067
zinc finger protein 1067
chr4_-_28651054 2.85 ENSDART00000167212
CABZ01050663.1
ENSDARG00000104584
chr19_+_27339056 2.85 ENSDART00000148439
nelfe
negative elongation factor complex member E
chr8_+_36550246 2.84 ENSDART00000049230
pqbp1
polyglutamine binding protein 1
chr4_+_66073648 2.81 ENSDART00000162862
CT737127.2
ENSDARG00000101797
chr4_-_44504315 2.80 ENSDART00000177682
znf1046
zinc finger protein 1046
chr4_+_28452948 2.79 ENSDART00000150879
znf1067
zinc finger protein 1067
chr8_+_21101133 2.79 ENSDART00000056405
magoh
mago homolog, exon junction complex core component
chr4_-_48343469 2.78 ENSDART00000121664
znf1128
zinc finger protein 1128
chr4_+_42243145 2.74

chr4_-_29817874 2.74

chr18_-_5235925 2.73 ENSDART00000082087
nip7
NIP7, nucleolar pre-rRNA processing protein
chr3_-_16263615 2.72 ENSDART00000127309
eftud2
elongation factor Tu GTP binding domain containing 2
chr15_+_847111 2.71 ENSDART00000158679
si:dkey-7i4.13
si:dkey-7i4.13
chr4_+_52851409 2.61

chr13_-_3801122 2.56

chr9_+_23118780 2.56 ENSDART00000061299
tsn
translin
KN149695v1_+_67009 2.55 ENSDART00000178024
ENSDARG00000107779
ENSDARG00000107779
chr4_+_56143439 2.54 ENSDART00000178597
si:ch211-212k5.1
si:ch211-212k5.1
chr1_+_29058085 2.53 ENSDART00000133905
pcca
propionyl CoA carboxylase, alpha polypeptide
chr4_-_55040981 2.53 ENSDART00000158368
BX957361.1
ENSDARG00000101664
chr4_+_33477747 2.53 ENSDART00000150417
znf1090
zinc finger protein 1090
chr19_-_3115104 2.51 ENSDART00000093146
bop1
block of proliferation 1
chr4_+_29390607 2.51 ENSDART00000160629
CR847895.1
ENSDARG00000099043
chr15_+_23787340 2.50 ENSDART00000011447
sae1
SUMO1 activating enzyme subunit 1
chr4_-_30339583 2.46 ENSDART00000171279
si:dkey-233e3.3
si:dkey-233e3.3
chr15_-_734338 2.44 ENSDART00000155878
si:dkey-7i4.23
si:dkey-7i4.23
chr15_+_926222 2.43 ENSDART00000156395
si:dkey-7i4.9
si:dkey-7i4.9
chr4_-_43806218 2.42 ENSDART00000153885
si:dkey-7j22.1
si:dkey-7j22.1
chr8_-_53165501 2.42 ENSDART00000135982
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr4_-_30124515 2.41

chr4_-_72584439 2.41 ENSDART00000174112
si:cabz01071911.4
si:cabz01071911.4
chr4_-_72067910 2.41 ENSDART00000170308
BX855614.3
ENSDARG00000101193
chr15_+_903146 2.40 ENSDART00000154083
si:dkey-7i4.12
si:dkey-7i4.12
chr4_-_49071258 2.39 ENSDART00000162560
BX855613.1
ENSDARG00000098743
chr15_+_862607 2.39 ENSDART00000174813
si:dkey-7i4.7
si:dkey-7i4.7
chr15_+_889995 2.36 ENSDART00000157374
si:dkey-77f5.11
si:dkey-77f5.11
chr17_-_24684729 2.36

chr4_-_72132319 2.35 ENSDART00000159313
si:dkey-262g12.10
si:dkey-262g12.10
chr4_-_71846854 2.33 ENSDART00000115002
si:ch73-266f23.1
si:ch73-266f23.1
chr15_+_855739 2.32 ENSDART00000046783
zgc:113294
zgc:113294
chr4_-_64277290 2.32

chr22_+_3167367 2.32 ENSDART00000160604
ftsj3
FtsJ homolog 3 (E. coli)
chr7_-_7564191 2.32 ENSDART00000084503
trmt10b
tRNA methyltransferase 10B
chr22_+_3167234 2.32 ENSDART00000176409
ftsj3
FtsJ homolog 3 (E. coli)
chr4_+_4825628 2.31 ENSDART00000150309
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr4_-_25526332 2.29 ENSDART00000142276
rbm17
RNA binding motif protein 17
chr15_+_1043976 2.28 ENSDART00000157310
si:dkey-77f5.8
si:dkey-77f5.8
chr21_-_11106675 2.26 ENSDART00000167666
dnajc21
DnaJ (Hsp40) homolog, subfamily C, member 21
chr20_+_35530285 2.26 ENSDART00000017485
sf3b6
splicing factor 3b, subunit 6
chr15_+_25700036 2.26 ENSDART00000135409
ENSDART00000162240
tsr1
TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
KN150672v1_-_47685 2.22

chr4_-_71906883 2.19 ENSDART00000150753
znf1015
zinc finger protein 1015
chr9_+_188559 2.18 ENSDART00000162764
rrp1
ribosomal RNA processing 1
chr12_-_29928951 2.17 ENSDART00000149077
ENSDART00000148847
trub1
TruB pseudouridine (psi) synthase family member 1
chr10_+_3427790 2.15 ENSDART00000081599
ptpn11a
protein tyrosine phosphatase, non-receptor type 11, a
chr4_+_40616952 2.15 ENSDART00000152116
znf1062
zinc finger protein 1062
KN150183v1_+_12947 2.14

chr2_+_21947682 2.12 ENSDART00000112014
mplkip
M-phase specific PLK1 interacting protein
chr6_-_6516441 2.11 ENSDART00000150995
si:dkey-261j15.2
si:dkey-261j15.2
chr5_+_25599354 2.10 ENSDART00000144303
ENSDARG00000035573
ENSDARG00000035573
chr19_+_27338938 2.07 ENSDART00000149988
nelfe
negative elongation factor complex member E
chr4_-_72213373 2.06

chr1_+_29058115 2.06 ENSDART00000135252
pcca
propionyl CoA carboxylase, alpha polypeptide
chr5_+_60113297 2.06 ENSDART00000125537
CABZ01069006.1
ENSDARG00000087185
chr2_-_58446028 2.05 ENSDART00000111651
ENSDARG00000078442
ENSDARG00000078442
chr4_+_58947953 2.04

chr3_+_40142679 2.04 ENSDART00000009411
bud31
BUD31 homolog (S. cerevisiae)
chr3_-_9504876 2.03 ENSDART00000128731
rnps1
RNA binding protein S1, serine-rich domain
chr16_+_32128415 2.03 ENSDART00000137029
prpf31
PRP31 pre-mRNA processing factor 31 homolog (yeast)
chr1_+_18390553 2.02 ENSDART00000002886
ENSDART00000158745
exosc9
exosome component 9
chr4_-_72468331 2.02 ENSDART00000174085
CABZ01071909.3
ENSDARG00000105818
chr23_-_43531724 2.01 ENSDART00000055564
rprd1b
regulation of nuclear pre-mRNA domain containing 1B
chr16_-_21277161 2.01

chr10_-_23130343 2.00 ENSDART00000148333
nle1
notchless homolog 1 (Drosophila)
chr5_+_35355253 1.99 ENSDART00000074630
zgc:103697
zgc:103697
chr6_+_3556145 1.99 ENSDART00000041627
ssb
Sjogren syndrome antigen B (autoantigen La)
chr4_+_47201306 1.99 ENSDART00000150289
si:ch211-234c11.2
si:ch211-234c11.2
chr4_+_46414646 1.96 ENSDART00000179615
BX324155.2
ENSDARG00000107359
chr5_+_1699963 1.94 ENSDART00000156224
dhx33
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr4_-_71353374 1.91

chr12_+_36414886 1.88 ENSDART00000171268
map2k6
mitogen-activated protein kinase kinase 6
chr4_-_62773293 1.87 ENSDART00000160787
znf1105
zinc finger protein 1105
chr13_-_36015609 1.87 ENSDART00000044115
med6
mediator complex subunit 6
chr4_-_36607316 1.87

chr22_+_1391146 1.86

chr4_-_48945944 1.83

chr4_-_71807043 1.82 ENSDART00000138333
si:ch73-120g24.4
si:ch73-120g24.4
chr15_-_784846 1.81 ENSDART00000155533
im:7143333
im:7143333
chr4_+_67836787 1.80 ENSDART00000168400
znf1117
zinc finger protein 1117
KN150703v1_-_47289 1.80 ENSDART00000168391
CABZ01081752.1
ENSDARG00000099245
chr4_-_72146177 1.80 ENSDART00000150546
si:dkey-262g12.3
si:dkey-262g12.3
chr4_+_42865142 1.78 ENSDART00000150797
znf1073
zinc finger protein 1073
chr4_-_71830240 1.78

chr17_+_53277665 1.78 ENSDART00000129236
wu:fe17e08
wu:fe17e08
chr15_+_666833 1.78 ENSDART00000157207
si:ch211-210b2.1
si:ch211-210b2.1
chr1_+_19071918 1.77 ENSDART00000138276
ENSDARG00000077648
ENSDARG00000077648
chr9_-_41072329 1.77 ENSDART00000066424
pofut2
protein O-fucosyltransferase 2
chr4_-_52603344 1.77

chr4_-_29167253 1.76 ENSDART00000160579
CR388132.2
ENSDARG00000101782
chr5_+_32687543 1.75 ENSDART00000123210
med22
mediator complex subunit 22
chr4_+_33077499 1.74

chr4_+_60620432 1.73

chr15_-_46439026 1.73 ENSDART00000125211
ENSDARG00000087950
ENSDARG00000087950
chr23_-_43531791 1.72 ENSDART00000055564
rprd1b
regulation of nuclear pre-mRNA domain containing 1B
chr4_-_70349899 1.69

chr4_-_64425534 1.68

chr15_+_1018191 1.68

chr4_+_57490141 1.66

chr4_+_59886564 1.66 ENSDART00000160943
ENSDART00000158840
CABZ01038376.1
ENSDARG00000105038
chr25_+_14302256 1.66 ENSDART00000130548
ciapin1
cytokine induced apoptosis inhibitor 1
chr12_-_1378010 1.66 ENSDART00000152308
MED9
mediator complex subunit 9

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 10.1 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
1.0 3.1 GO:0050864 regulation of B cell activation(GO:0050864)
1.0 3.9 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.8 3.0 GO:0046929 negative regulation of neurotransmitter secretion(GO:0046929) response to cAMP(GO:0051591) cellular response to cAMP(GO:0071320) negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.7 3.5 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.5 2.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.5 2.2 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.5 1.6 GO:0070476 rRNA (guanine-N7)-methylation(GO:0070476)
0.5 9.7 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.5 3.0 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.5 1.5 GO:1903523 negative regulation of heart contraction(GO:0045822) negative regulation of blood circulation(GO:1903523)
0.4 13.1 GO:0009408 response to heat(GO:0009408)
0.4 1.1 GO:0019364 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.3 1.9 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.3 1.0 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.3 0.8 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2 5.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.2 0.7 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.2 2.3 GO:0006004 fucose metabolic process(GO:0006004)
0.2 1.6 GO:0006382 adenosine to inosine editing(GO:0006382)
0.2 2.5 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.2 0.9 GO:0051031 tRNA transport(GO:0051031)
0.2 2.5 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.2 1.8 GO:0071428 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.2 0.5 GO:0010259 multicellular organism aging(GO:0010259)
0.1 0.9 GO:0006309 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.1 3.2 GO:0008333 endosome to lysosome transport(GO:0008333)
0.1 0.6 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.1 0.8 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 2.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 4.1 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.1 1.3 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 0.6 GO:0036372 opsin transport(GO:0036372)
0.1 0.7 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.4 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.1 2.1 GO:0003146 heart jogging(GO:0003146)
0.1 3.0 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 1.7 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 1.8 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 10.6 GO:0006364 rRNA processing(GO:0006364)
0.1 3.7 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.1 212.7 GO:0006355 regulation of transcription, DNA-templated(GO:0006355)
0.1 1.3 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.1 1.7 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.5 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 16.5 GO:0008380 RNA splicing(GO:0008380)
0.0 0.9 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 2.9 GO:0043068 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.0 0.5 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 4.6 GO:0016042 lipid catabolic process(GO:0016042)
0.0 4.3 GO:0006396 RNA processing(GO:0006396)
0.0 0.5 GO:0051788 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.0 0.1 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.5 GO:0006473 protein acetylation(GO:0006473)
0.0 3.6 GO:0016070 RNA metabolic process(GO:0016070)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 10.1 GO:0032021 NELF complex(GO:0032021)
0.7 2.2 GO:0071020 post-spliceosomal complex(GO:0071020)
0.7 11.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.7 2.0 GO:0061574 ASAP complex(GO:0061574)
0.6 2.5 GO:0070545 PeBoW complex(GO:0070545)
0.4 3.5 GO:0005687 U4 snRNP(GO:0005687) U2-type precatalytic spliceosome(GO:0071005)
0.4 3.5 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.3 0.9 GO:0032545 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.3 0.8 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.2 3.1 GO:0070847 core mediator complex(GO:0070847)
0.2 3.9 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.2 2.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 0.6 GO:0070209 ASTRA complex(GO:0070209)
0.2 3.5 GO:0071011 precatalytic spliceosome(GO:0071011)
0.2 0.9 GO:0031501 mannosyltransferase complex(GO:0031501)
0.2 3.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 5.2 GO:0032040 small-subunit processome(GO:0032040)
0.1 2.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.9 GO:0044447 axoneme part(GO:0044447)
0.1 1.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 3.6 GO:0016592 mediator complex(GO:0016592)
0.1 3.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.2 GO:0005736 DNA-directed RNA polymerase II, core complex(GO:0005665) DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 3.7 GO:0005694 chromosome(GO:0005694)
0.1 3.7 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.1 3.5 GO:0031201 SNARE complex(GO:0031201)
0.0 10.4 GO:0005730 nucleolus(GO:0005730)
0.0 4.5 GO:0016607 nuclear speck(GO:0016607)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.7 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.5 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 3.3 GO:0005681 spliceosomal complex(GO:0005681)
0.0 2.0 GO:0044297 cell body(GO:0044297)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 133.7 GO:0005634 nucleus(GO:0005634)
0.0 1.3 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.1 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.0 GO:0005882 intermediate filament(GO:0005882)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.2 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
1.2 3.5 GO:0030623 U5 snRNA binding(GO:0030623)
0.6 2.5 GO:0008022 protein C-terminus binding(GO:0008022)
0.6 4.6 GO:0016421 CoA carboxylase activity(GO:0016421)
0.5 2.2 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.5 3.7 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.5 2.3 GO:0046922 peptide-O-fucosyltransferase activity(GO:0046922)
0.4 2.9 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.4 2.5 GO:0034511 U3 snoRNA binding(GO:0034511)
0.4 1.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.3 1.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.3 0.8 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.2 4.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 0.8 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.2 1.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.2 3.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.2 2.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 222.1 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.1 1.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 0.9 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 5.0 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.1 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 1.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 3.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.7 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 1.0 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 3.1 GO:0004521 endoribonuclease activity(GO:0004521)
0.1 0.4 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 1.7 GO:0017069 snRNA binding(GO:0017069)
0.0 5.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 42.3 GO:0003723 RNA binding(GO:0003723)
0.0 0.5 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 1.2 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 2.9 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.2 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 3.4 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 0.2 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.5 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 13.1 PID P73PATHWAY p73 transcription factor network
0.2 1.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.9 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 4.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 3.9 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 4.8 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 8.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.7 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 3.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 1.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK