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Results for creb3l2

Z-value: 0.67

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Transcription factors associated with creb3l2

Gene Symbol Gene ID Gene Info
ENSDARG00000063563 cAMP responsive element binding protein 3-like 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
creb3l2dr10_dc_chr4_-_4743320_4743409-0.524.0e-02Click!

Activity profile of creb3l2 motif

Sorted Z-values of creb3l2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of creb3l2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_+_59972297 0.94

chr2_-_6153363 0.65 ENSDART00000037698
uridine-cytidine kinase 2b
chr20_+_32503118 0.63 ENSDART00000018640
sorting nexin 3
chr7_+_15479700 0.62

chr17_+_28689850 0.60 ENSDART00000126967
striatin, calmodulin binding protein 3
chr3_+_42217236 0.60 ENSDART00000168228
transmembrane protein 184a
chr14_+_47040687 0.59 ENSDART00000113469
nocturnin a
chr20_+_51248443 0.59 ENSDART00000134416
im:7140055
chr18_-_37271104 0.59 ENSDART00000132230
SIX homeobox 5
chr10_-_44441390 0.58 ENSDART00000160231
strawberry notch homolog 1 (Drosophila)
chr17_+_25815708 0.57 ENSDART00000164160
acyl-CoA synthetase short-chain family member 1
chr25_-_7490206 0.56 ENSDART00000163018
Bet1 golgi vesicular membrane trafficking protein-like
chr2_+_51265445 0.53 ENSDART00000161254
eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)
chr7_-_27787236 0.51 ENSDART00000173842
si:ch211-235p24.2
chr4_+_76572863 0.50 ENSDART00000156692
ADP-ribosylation factor GTPase activating protein 3
chr25_+_35782970 0.45 ENSDART00000125440
histone 1, H4, like
chr8_+_8660457 0.45 ENSDART00000137780
ubiquitously-expressed, prefoldin-like chaperone
chr5_-_54091790 0.44 ENSDART00000150070
cyclin B1
chr25_-_1243081 0.43 ENSDART00000156062
calmodulin-like 4b
chr11_+_25058986 0.42 ENSDART00000122249
topoisomerase (DNA) I, like
chr23_+_38335290 0.40 ENSDART00000177981
ENSDART00000178842
ENSDARG00000109193
chr1_-_55072271 0.39 ENSDART00000142244
DnaJ (Hsp40) homolog, subfamily B, member 1b
chr11_+_25058714 0.39 ENSDART00000065949
topoisomerase (DNA) I, like
chr25_-_34616837 0.39 ENSDART00000137502
si:ch73-36p18.1
chr10_-_1185831 0.38 ENSDART00000114261
bone morphogenetic protein receptor, type IBb
chr18_-_37271027 0.38 ENSDART00000132230
SIX homeobox 5
chr7_-_72161793 0.37 ENSDART00000162933
mitochondrial ribosomal protein L21
chr20_+_29306863 0.37 ENSDART00000141252
katanin p80 subunit B-like 1
chr5_-_21627098 0.37 ENSDART00000138606
LAS1-like, ribosome biogenesis factor
chr4_-_16893974 0.36 ENSDART00000124627
serine/threonine kinase receptor associated protein
chr13_+_36831946 0.33 ENSDART00000024386
FERM domain containing 6
chr7_+_38444768 0.33 ENSDART00000024590
synaptotagmin XIII
chr19_+_7254917 0.33 ENSDART00000123934
hydroxysteroid (17-beta) dehydrogenase 8
chr20_+_29307039 0.32 ENSDART00000152949
katanin p80 subunit B-like 1
chr5_-_36499541 0.32

chr21_-_5774127 0.32 ENSDART00000009241
ribosomal protein L35
chr17_-_28780394 0.32 ENSDART00000167897
ENSDART00000134735
sec1 family domain containing 1
chr5_-_54091732 0.31 ENSDART00000150070
cyclin B1
chr2_-_6153411 0.30 ENSDART00000037698
uridine-cytidine kinase 2b
chr3_-_15913190 0.30

chr20_+_15666406 0.30 ENSDART00000063917
si:dkey-86e18.1
chr20_-_46079578 0.29 ENSDART00000153228
ENSDARG00000096676
chr1_-_53021646 0.29

chr13_-_25418278 0.28 ENSDART00000077655
ENSDART00000168099
ENSDART00000135788
minichromosome maintenance complex binding protein
chr20_+_29306677 0.28 ENSDART00000141252
katanin p80 subunit B-like 1
chr16_-_31664756 0.27 ENSDART00000176939
PHD finger protein 20-like 1
chr17_-_44326992 0.27 ENSDART00000148786
exocyst complex component 5
chr2_-_39049391 0.27 ENSDART00000044331
coatomer protein complex, subunit beta 2
chr20_+_29306945 0.27 ENSDART00000141252
katanin p80 subunit B-like 1
chr13_+_34563757 0.27 ENSDART00000133661
taspase, threonine aspartase, 1
chr7_+_15059782 0.27 ENSDART00000165683
mesoderm posterior ba
chr20_-_46079529 0.26 ENSDART00000153228
ENSDARG00000096676
chr3_+_43361682 0.26 ENSDART00000168784
NSE1 homolog, SMC5-SMC6 complex component
chr2_+_54267946 0.25 ENSDART00000015535
catenin, beta like 1
chr3_+_42217187 0.24 ENSDART00000168228
transmembrane protein 184a
chr22_+_31110716 0.24 ENSDART00000077063
SEC13 homolog, nuclear pore and COPII coat complex component
chr20_-_13244237 0.24 ENSDART00000124470
integrator complex subunit 7
chr14_+_2820269 0.24 ENSDART00000162445
HMG box domain containing 3
chr25_-_7546532 0.23 ENSDART00000131583
Bet1 golgi vesicular membrane trafficking protein-like
chr21_+_45622590 0.22 ENSDART00000162422
secretion associated, Ras related GTPase 1B
chr20_-_7079412 0.22 ENSDART00000040793
sirtuin 5
chr3_+_22204475 0.21 ENSDART00000055676
ENSDARG00000038186
chr16_-_20488542 0.21 ENSDART00000059623
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
chr8_+_8660574 0.21 ENSDART00000137780
ubiquitously-expressed, prefoldin-like chaperone
chr13_-_25452733 0.21

chr3_+_43361636 0.21 ENSDART00000161277
NSE1 homolog, SMC5-SMC6 complex component
chr15_+_666833 0.20 ENSDART00000157207
si:ch211-210b2.1
chr2_-_55565099 0.20 ENSDART00000149062
RAB8A, member RAS oncogene family
chr15_+_32561282 0.20 ENSDART00000162663
si:dkey-285b23.3
chr2_-_45118469 0.20 ENSDART00000018818
mitochondrial E3 ubiquitin protein ligase 1a
chr5_+_1737449 0.19 ENSDART00000064088
vitamin K epoxide reductase complex, subunit 1-like 1
chr7_-_69114957 0.19

chr15_+_23272957 0.19 ENSDART00000006085
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr6_+_251026 0.19 ENSDART00000042970
activating transcription factor 4a
chr13_-_29571309 0.19 ENSDART00000139773
ENSDARG00000093614
chr14_+_47040931 0.19 ENSDART00000113469
nocturnin a
chr5_+_59394222 0.19

chr20_+_29307283 0.18 ENSDART00000153016
katanin p80 subunit B-like 1
chr14_-_21779536 0.18

chr13_+_36832145 0.17 ENSDART00000024386
FERM domain containing 6
chr14_-_35513309 0.17 ENSDART00000173343
platelet derived growth factor c
chr15_+_1569674 0.17 ENSDART00000130413
structural maintenance of chromosomes 4
chr1_-_55072064 0.17 ENSDART00000142244
DnaJ (Hsp40) homolog, subfamily B, member 1b
chr24_-_33475705 0.17 ENSDART00000074161
solute carrier family 4 (anion exchanger), member 2b
chr13_+_36832090 0.17 ENSDART00000024386
FERM domain containing 6
chr25_-_20633069 0.17 ENSDART00000172170
si:ch211-127m7.2
chr16_+_20488737 0.16 ENSDART00000059619
FK506 binding protein 14
chr12_-_9094888 0.16 ENSDART00000066471
ADAM metallopeptidase domain 8b
chr20_+_29307142 0.16 ENSDART00000153016
katanin p80 subunit B-like 1
KN150699v1_+_15349 0.16 ENSDART00000167656
cellular repressor of E1A-stimulated genes 1
chr8_+_23192085 0.16 ENSDART00000032996
ENSDART00000137536
pancreatic progenitor cell differentiation and proliferation factor a
chr8_-_17736487 0.15 ENSDART00000063592
ENSDART00000175064
protein kinase C, zeta
chr5_+_68505700 0.14 ENSDART00000136656
selenoprotein M
chr20_-_7079708 0.13 ENSDART00000040793
sirtuin 5
chr2_-_10602948 0.13 ENSDART00000016369
wntless Wnt ligand secretion mediator
chr24_+_23599223 0.12

chr19_-_25173832 0.12 ENSDART00000161016
si:dkey-154b15.1
chr7_+_69664384 0.12 ENSDART00000058763
SEC24 homolog D, COPII coat complex component
chr3_+_42217445 0.12 ENSDART00000168228
transmembrane protein 184a
chr21_-_19883010 0.12 ENSDART00000137307
protein phosphatase 1, regulatory subunit 3B
chr11_-_7146819 0.11 ENSDART00000172879
small integral membrane protein 7
chr3_-_18234622 0.11 ENSDART00000027630
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2a
chr21_+_45622095 0.10 ENSDART00000162422
secretion associated, Ras related GTPase 1B
chr21_-_37404533 0.10 ENSDART00000129439
ENSDARG00000091187
chr23_+_38335341 0.09 ENSDART00000177981
ENSDART00000178842
ENSDARG00000109193
chr4_+_344355 0.09 ENSDART00000142225
ENSDART00000163436
transmembrane protein 181
chr8_-_17736169 0.09 ENSDART00000063592
ENSDART00000175064
protein kinase C, zeta
chr11_-_7146782 0.09 ENSDART00000172823
small integral membrane protein 7
chr1_+_25750825 0.08 ENSDART00000046376
GTPase activating protein (SH3 domain) binding protein 2
chr21_-_3462128 0.08 ENSDART00000139194
dymeclin
chr20_-_7079663 0.08 ENSDART00000040793
sirtuin 5
chr14_+_21779325 0.08 ENSDART00000106147
solute carrier family 43 (amino acid system L transporter), member 1a
chr5_-_28368834 0.08

chr3_+_39426379 0.07 ENSDART00000020741
aldolase a, fructose-bisphosphate, a
chr17_+_28690237 0.07 ENSDART00000126967
striatin, calmodulin binding protein 3
chr4_-_23028510 0.07 ENSDART00000040033
ENSDART00000160375
nucleoporin 107
chr8_-_8659980 0.07 ENSDART00000046712
zgc:86609
chr20_-_20412830 0.07 ENSDART00000114779
ENSDARG00000079369
chr7_+_15479520 0.07

chr13_-_40189984 0.06

chr22_-_800449 0.06 ENSDART00000123487
zgc:153675
chr17_+_44327269 0.06 ENSDART00000045882
adaptor-related protein complex 5, mu 1 subunit
chr19_+_47846675 0.06 ENSDART00000041114
proteasome subunit beta 2
chr1_-_25750237 0.06 ENSDART00000125690
integrator complex subunit 12
chr10_-_44441481 0.06 ENSDART00000160231
strawberry notch homolog 1 (Drosophila)
chr12_+_33793495 0.06 ENSDART00000152988
major facilitator superfamily domain containing 13A
chr25_-_36512943 0.06 ENSDART00000114508
hypoxanthine phosphoribosyltransferase 1, like
chr17_-_28794581 0.06 ENSDART00000132811
G2/M-phase specific E3 ubiquitin protein ligase
chr22_-_4715399 0.04 ENSDART00000122341
ENSDART00000161345
zinc finger RNA binding protein 2
chr3_+_22204569 0.03 ENSDART00000055676
ENSDARG00000038186
chr15_-_43954665 0.03 ENSDART00000041249
cysteine and histidine-rich domain (CHORD) containing 1a
chr3_+_22724101 0.03 ENSDART00000167127
ENSDARG00000098353
chr10_-_44441197 0.03 ENSDART00000160231
strawberry notch homolog 1 (Drosophila)
chr20_-_13244278 0.02 ENSDART00000124470
integrator complex subunit 7
chr5_+_56658275 0.02 ENSDART00000149646
solute carrier family 31 (copper transporter), member 1
chr25_+_34357376 0.02 ENSDART00000149782
carbohydrate sulfotransferase 6
chr10_-_45535333 0.02

chr21_-_45621982 0.02 ENSDART00000160530
SEC24 homolog A, COPII coat complex component
chr5_-_62963536 0.01 ENSDART00000050865
surfeit gene 4, like
chr2_-_11720585 0.01 ENSDART00000019392
short chain dehydrogenase/reductase family 16C, member 5a
chr2_+_54268010 0.01 ENSDART00000170799
catenin, beta like 1
chr8_+_46378250 0.01 ENSDART00000129661
ENSDART00000084081
8-oxoguanine DNA glycosylase
chr8_-_46037132 0.00 ENSDART00000135138
si:ch211-119d14.3
chr17_-_28794619 0.00 ENSDART00000001444
G2/M-phase specific E3 ubiquitin protein ligase

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.4 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 1.0 GO:0044206 pyrimidine-containing compound salvage(GO:0008655) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206) CTP salvage(GO:0044211)
0.1 0.7 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 0.4 GO:0036049 regulation of ketone biosynthetic process(GO:0010566) protein demalonylation(GO:0036046) peptidyl-lysine demalonylation(GO:0036047) protein desuccinylation(GO:0036048) peptidyl-lysine desuccinylation(GO:0036049) protein deglutarylation(GO:0061698)
0.1 0.6 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.1 0.3 GO:0070863 regulation of COPII vesicle coating(GO:0003400) regulation of protein exit from endoplasmic reticulum(GO:0070861) positive regulation of protein exit from endoplasmic reticulum(GO:0070863) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.1 0.3 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.2 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 0.3 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.1 0.8 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.6 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.2 GO:0035627 ceramide transport(GO:0035627)
0.0 0.1 GO:0061355 Wnt protein secretion(GO:0061355)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.2 GO:0090049 regulation of cell migration involved in sprouting angiogenesis(GO:0090049)
0.0 1.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.2 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.2 GO:0070309 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.0 0.7 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.6 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.5 GO:0006301 postreplication repair(GO:0006301)
0.0 0.1 GO:0051292 pore complex assembly(GO:0046931) nuclear pore complex assembly(GO:0051292)
0.0 0.7 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.3 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.6 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.3 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 1.0 GO:0045765 regulation of angiogenesis(GO:0045765)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 0.8 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.2 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.1 0.7 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.6 GO:0030904 retromer complex(GO:0030904)
0.0 0.5 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.0 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.3 GO:0044545 NSL complex(GO:0044545)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.4 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.4 GO:0036054 protein-malonyllysine demalonylase activity(GO:0036054) protein-succinyllysine desuccinylase activity(GO:0036055) protein-glutaryllysine deglutarylase activity(GO:0061697)
0.1 0.8 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.6 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.2 GO:0047690 aspartyltransferase activity(GO:0047690)
0.1 0.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0035620 ceramide transporter activity(GO:0035620) sphingolipid transporter activity(GO:0046624) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.0 0.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0048038 quinone binding(GO:0048038)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.2 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.2 PID TXA2PATHWAY Thromboxane A2 receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 0.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends