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Results for crx+otx5

Z-value: 1.48

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Transcription factors associated with crx+otx5

Gene Symbol Gene ID Gene Info
crx
ENSDARG00000011989 cone-rod homeobox
otx5
ENSDARG00000043483 orthodenticle homolog 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
otx5dr10_dc_chr15_+_47316316_47316434-0.332.2e-01Click!
crxdr10_dc_chr5_+_36332564_36332612-0.292.7e-01Click!

Activity profile of crx+otx5 motif

Sorted Z-values of crx+otx5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of crx+otx5

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr12_-_4264663 6.81 ENSDART00000152521
ca15b
carbonic anhydrase XVb
chr20_+_9141086 4.12 ENSDART00000064144
ENSDART00000144396
bpnt1
bisphosphate nucleotidase 1
chr14_+_44703094 3.39

chr15_+_44177774 3.05

chr9_+_18821640 2.98 ENSDART00000006514
gtf2f2b
general transcription factor IIF, polypeptide 2b
chr15_+_44177693 2.97

chr17_+_16038358 2.91 ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr12_-_13866903 2.91 ENSDART00000152400
dbf4b
DBF4 zinc finger B
chr3_-_26052785 2.69 ENSDART00000147517
si:ch211-11k18.4
si:ch211-11k18.4
chr22_+_25113293 2.67 ENSDART00000171851
si:ch211-226h8.4
si:ch211-226h8.4
chr23_+_39961676 2.51 ENSDART00000161881
ENSDARG00000104435
ENSDARG00000104435
chr11_-_2437396 2.49

chr15_+_40232397 2.34 ENSDART00000154947
ngef
neuronal guanine nucleotide exchange factor
chr12_-_13866811 2.29 ENSDART00000152400
dbf4b
DBF4 zinc finger B
chr8_-_3354396 2.24 ENSDART00000169430
ENSDART00000167187
ENSDART00000170478
FUT9 (1 of many)
fut9b
fucosyltransferase 9
fucosyltransferase 9b
chr1_+_39315964 2.16 ENSDART00000011727
ccdc149b
coiled-coil domain containing 149b
chr25_-_36512943 2.10 ENSDART00000114508
hprt1l
hypoxanthine phosphoribosyltransferase 1, like
chr17_+_16038103 1.98 ENSDART00000155005
si:ch73-204p21.2
si:ch73-204p21.2
chr4_-_3184182 1.95

chr3_-_26052601 1.95 ENSDART00000147517
si:ch211-11k18.4
si:ch211-11k18.4
chr3_+_38497816 1.95

chr24_+_36429525 1.92 ENSDART00000062722
pus3
pseudouridylate synthase 3
chr19_-_2148053 1.90 ENSDART00000020497
snx13
sorting nexin 13
chr5_-_68408107 1.88 ENSDART00000109761
ENSDART00000156681
ENSDART00000167680
ENSDARG00000076888
ENSDARG00000076888
chr3_+_16692138 1.84 ENSDART00000023985
zgc:153952
zgc:153952
chr3_+_16692090 1.82 ENSDART00000023985
zgc:153952
zgc:153952
chr3_+_17783319 1.81 ENSDART00000104299
cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr8_+_25940758 1.74 ENSDART00000140626
ENSDARG00000061023
ENSDARG00000061023
chr24_+_10758290 1.73 ENSDART00000106272
si:dkey-37o8.1
si:dkey-37o8.1
chr17_+_50622734 1.70 ENSDART00000049464
fermt2
fermitin family member 2
chr16_+_25370991 1.68 ENSDART00000154112
si:dkey-29h14.10
si:dkey-29h14.10
chr20_-_15205248 1.66 ENSDART00000034011
fmo5
flavin containing monooxygenase 5
chr24_+_39237314 1.64 ENSDART00000155346
tbc1d24
TBC1 domain family, member 24
chr13_+_40689102 1.60 ENSDART00000016960
prkg1a
protein kinase, cGMP-dependent, type Ia
chr10_-_1933761 1.58 ENSDART00000101023
tdgf1
teratocarcinoma-derived growth factor 1
chr12_-_4264610 1.54 ENSDART00000152377
ca15b
carbonic anhydrase XVb
chr15_+_23721725 1.53 ENSDART00000078336
klc3
kinesin light chain 3
chr24_-_28227116 1.52 ENSDART00000148618
prkag2a
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr20_-_34851706 1.48 ENSDART00000148066
znf395b
zinc finger protein 395b
chr10_-_25725495 1.44 ENSDART00000177220
AL837524.2
ENSDARG00000108650
chr24_+_16861058 1.42 ENSDART00000149149
zfx
zinc finger protein, X-linked
chr19_-_9584480 1.42 ENSDART00000091615
iffo1a
intermediate filament family orphan 1a
chr25_-_31352866 1.41 ENSDART00000041740
ubl7a
ubiquitin-like 7a (bone marrow stromal cell-derived)
chr20_+_35156812 1.40

chr8_+_36527653 1.40 ENSDART00000136418
ENSDART00000061378
sf3a1
splicing factor 3a, subunit 1
chr8_+_2484943 1.39 ENSDART00000101137
gle1
GLE1 RNA export mediator homolog (yeast)
chr23_-_24328931 1.38

chr14_-_16118942 1.37

chr24_+_16861121 1.36 ENSDART00000149149
zfx
zinc finger protein, X-linked
chr24_-_21224397 1.36 ENSDART00000156537
spice1
spindle and centriole associated protein 1
chr3_+_25776714 1.35 ENSDART00000170324
tom1
target of myb1 membrane trafficking protein
chr20_+_6543305 1.34 ENSDART00000135005
ENSDART00000166356
si:ch211-191a24.4
si:ch211-191a24.4
chr11_-_2437361 1.31

chr14_+_1106141 1.30 ENSDART00000106708
sec24b
SEC24 homolog B, COPII coat complex component
chr19_+_10742944 1.27 ENSDART00000165653
ago3b
argonaute RISC catalytic component 3b
chr16_+_40093596 1.27 ENSDART00000132457
trmt11
tRNA methyltransferase 11 homolog (S. cerevisiae)
chr2_-_4191540 1.26 ENSDART00000158335
rab18b
RAB18B, member RAS oncogene family
chr9_+_42656327 1.26

chr7_-_41601001 1.25 ENSDART00000174258
zgc:92818
zgc:92818
chr24_+_440200 1.22

chr11_-_11353309 1.22 ENSDART00000016677
zgc:77929
zgc:77929
chr13_-_35401769 1.22 ENSDART00000016793
memo1
mediator of cell motility 1
chr24_-_21224371 1.20 ENSDART00000156537
spice1
spindle and centriole associated protein 1
chr11_-_6858626 1.19 ENSDART00000168372
lsm4
LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
chr5_-_45244910 1.19

chr10_+_20435169 1.17 ENSDART00000160803
r3hcc1
R3H domain and coiled-coil containing 1
chr8_-_3354350 1.16 ENSDART00000169430
ENSDART00000167187
FUT9 (1 of many)
fucosyltransferase 9
chr10_-_25059072 1.14 ENSDART00000040733
cd209
CD209 molecule
chr24_+_36430199 1.13

chr5_-_23525132 1.13 ENSDART00000051546
rps6ka3a
ribosomal protein S6 kinase a, polypeptide 3a
chr22_+_26270259 1.13 ENSDART00000060898
mrps28
mitochondrial ribosomal protein S28
chr5_+_29301998 1.12 ENSDART00000175940
BX284646.1
ENSDARG00000106174
chr19_+_16159980 1.11 ENSDART00000151169
gmeb1
glucocorticoid modulatory element binding protein 1
chr25_+_181958 1.09 ENSDART00000155412
RPS17
ribosomal protein S17
chr21_+_3624059 1.07 ENSDART00000111699
tor1
torsin family 1
chr8_-_50151276 1.07

chr17_+_25407766 1.06 ENSDART00000121848
srrm1
serine/arginine repetitive matrix 1
chr24_+_35296732 1.06 ENSDART00000172652
pcmtd1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr19_-_25842574 1.03 ENSDART00000036854
glcci1
glucocorticoid induced 1
chr5_-_22090338 1.02

chr3_+_48811909 0.97 ENSDART00000136051
prkcsh
protein kinase C substrate 80K-H
chr24_+_35297193 0.97 ENSDART00000075142
ENSDART00000158801
pcmtd1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr3_+_23963926 0.96 ENSDART00000138270
copz2
coatomer protein complex, subunit zeta 2
chr16_+_25370955 0.94 ENSDART00000154112
si:dkey-29h14.10
si:dkey-29h14.10
chr23_+_19271879 0.93 ENSDART00000047015
ccdc115
coiled-coil domain containing 115
chr9_-_12603178 0.90

chr8_-_28209155 0.90 ENSDART00000154912
BX664742.2
ENSDARG00000095929
chr16_-_40093241 0.89 ENSDART00000145278
si:dkey-29b11.3
si:dkey-29b11.3
chr17_+_26736703 0.89

chr20_-_43889302 0.89 ENSDART00000004601
laptm4a
lysosomal protein transmembrane 4 alpha
chr25_-_34235582 0.88 ENSDART00000137665
frs2b
fibroblast growth factor receptor substrate 2b
chr24_-_20782338 0.88 ENSDART00000130958
ccdc58
coiled-coil domain containing 58
chr8_+_2597651 0.88 ENSDART00000165943
fam102aa
family with sequence similarity 102, member Aa
chr10_-_1933874 0.88 ENSDART00000101023
tdgf1
teratocarcinoma-derived growth factor 1
chr15_+_34106908 0.87

chr3_-_20807407 0.87 ENSDART00000164601
ndufa4l
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 4, like
chr3_+_48811632 0.86 ENSDART00000023814
prkcsh
protein kinase C substrate 80K-H
chr11_+_6872272 0.86 ENSDART00000075998
klhl26
kelch-like family member 26
chr1_+_35224410 0.85 ENSDART00000085021
ENSDART00000140144
mmaa
methylmalonic aciduria (cobalamin deficiency) cblA type
chr17_-_8435280 0.84 ENSDART00000127022
ENSDARG00000090072
ENSDARG00000090072
chr11_+_31417477 0.84 ENSDART00000139900
diaph3
diaphanous-related formin 3
chr15_+_24012650 0.83 ENSDART00000153951
myo18ab
myosin XVIIIAb
chr9_-_12603215 0.82

chr6_+_40835073 0.81 ENSDART00000011931
ruvbl1
RuvB-like AAA ATPase 1
chr12_+_11314303 0.80 ENSDART00000129495
si:rp71-19m20.1
si:rp71-19m20.1
chr5_-_3255080 0.80 ENSDART00000152108
hspb1
heat shock protein, alpha-crystallin-related, 1
chr25_-_34235633 0.79 ENSDART00000137665
frs2b
fibroblast growth factor receptor substrate 2b
chr4_-_71945633 0.78 ENSDART00000170170
znf1015
zinc finger protein 1015
chr2_+_55065658 0.77

chr7_+_20829933 0.76 ENSDART00000173612
serpinh2
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr3_+_48811662 0.76 ENSDART00000023814
prkcsh
protein kinase C substrate 80K-H
chr22_+_1769284 0.76 ENSDART00000164948
znf1169
zinc finger protein 1169
chr13_+_39056158 0.74 ENSDART00000131434
fam135a
family with sequence similarity 135, member A
chr23_-_36350571 0.74 ENSDART00000110478
zgc:174906
zgc:174906
chr10_+_6011791 0.73 ENSDART00000159216
hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr8_-_41271389 0.72 ENSDART00000170332
pop5
POP5 homolog, ribonuclease P/MRP subunit
chr18_+_38210277 0.72 ENSDART00000052703
nucb2b
nucleobindin 2b
chr2_+_55112111 0.71 ENSDART00000163834
rnf126
ring finger protein 126
chr20_+_48631844 0.71 ENSDART00000108884
prdm1c
PR domain containing 1c, with ZNF domain
chr20_+_23843178 0.70 ENSDART00000050559
sh3rf1
SH3 domain containing ring finger 1
chr21_-_39616469 0.69 ENSDART00000026766
aldocb
aldolase C, fructose-bisphosphate, b
chr17_-_25284780 0.67 ENSDART00000167992
ppie
peptidylprolyl isomerase E (cyclophilin E)
chr25_-_27279272 0.67 ENSDART00000148121
zgc:153935
zgc:153935
chr6_-_33940201 0.65 ENSDART00000132762
akr1a1b
aldo-keto reductase family 1, member A1b (aldehyde reductase)
chr25_-_36513113 0.65 ENSDART00000025494
hprt1l
hypoxanthine phosphoribosyltransferase 1, like
chr19_-_2147899 0.63 ENSDART00000020497
snx13
sorting nexin 13
chr20_+_29685379 0.63 ENSDART00000178617
adam17b
ADAM metallopeptidase domain 17b
chr9_-_7110860 0.61 ENSDART00000146609
coa5
cytochrome C oxidase assembly factor 5
chr3_-_26927151 0.61 ENSDART00000153542
CR954963.1
ENSDARG00000097153
chr11_-_18073851 0.59

chr2_-_54218077 0.59

chr19_-_3947422 0.59 ENSDART00000172271
thrap3b
thyroid hormone receptor associated protein 3b
chr5_+_34381412 0.58 ENSDART00000134795
ankra2
ankyrin repeat, family A (RFXANK-like), 2
chr11_+_3479741 0.56 ENSDART00000171621
pusl1
pseudouridylate synthase-like 1
chr6_-_33940469 0.55 ENSDART00000137268
akr1a1b
aldo-keto reductase family 1, member A1b (aldehyde reductase)
chr22_-_26269585 0.54 ENSDART00000043774
sde2
SDE2 telomere maintenance homolog (S. pombe)
chr18_-_17542397 0.53 ENSDART00000061000
bbs2
Bardet-Biedl syndrome 2
chr24_+_35296642 0.52 ENSDART00000172652
pcmtd1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr9_+_3547661 0.52 ENSDART00000008606
mettl8
methyltransferase like 8
chr7_+_28753102 0.52 ENSDART00000076425
cog4
component of oligomeric golgi complex 4
chr15_+_1018191 0.51

chr15_-_30975156 0.51

chr20_-_18836698 0.51 ENSDART00000142837
enpp5
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr20_+_34768464 0.51 ENSDART00000152836
elp3
elongator acetyltransferase complex subunit 3
chr14_-_40941231 0.50 ENSDART00000138917
arl13a
ADP-ribosylation factor-like 13A
chr3_+_23964015 0.50 ENSDART00000138270
copz2
coatomer protein complex, subunit zeta 2
chr11_-_6858313 0.50 ENSDART00000037824
lsm4
LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
chr8_+_36527535 0.48 ENSDART00000136418
ENSDART00000061378
sf3a1
splicing factor 3a, subunit 1
chr15_+_46800117 0.48

chr25_+_35771748 0.42

chr21_-_13688502 0.42 ENSDART00000024720
si:ch211-282j22.3
si:ch211-282j22.3
chr23_-_31340025 0.42 ENSDART00000139746
si:dkey-261l7.2
si:dkey-261l7.2
chr21_-_13599764 0.41

chr16_+_53391438 0.38 ENSDART00000010792
ptdss1a
phosphatidylserine synthase 1a
chr4_+_135858 0.37 ENSDART00000171845
gpr19
G protein-coupled receptor 19
chr17_-_49910160 0.36 ENSDART00000122747
tmem30aa
transmembrane protein 30Aa
chr16_+_24046996 0.32

chr20_+_23843436 0.32 ENSDART00000050559
sh3rf1
SH3 domain containing ring finger 1
KN149789v1_-_7443 0.31

chr6_-_17699766 0.30 ENSDART00000170597
rptor
regulatory associated protein of MTOR, complex 1
chr12_-_33358480 0.30 ENSDART00000105562
zgc:91940
zgc:91940
chr13_+_35402382 0.30 ENSDART00000163368
wdr27
WD repeat domain 27
chr3_-_26013660 0.30

chr3_-_23442774 0.29

chr20_-_15205171 0.29 ENSDART00000034011
fmo5
flavin containing monooxygenase 5
chr18_+_2902170 0.29 ENSDART00000170827
ccpg1
cell cycle progression 1
chr3_+_19515578 0.27 ENSDART00000007857
mettl2a
methyltransferase like 2A
chr7_-_66641207 0.26

chr7_-_66641971 0.25

chr6_-_39767422 0.25 ENSDART00000085277
pfkmb
phosphofructokinase, muscle b
chr17_+_35149038 0.25 ENSDART00000163557
asap2a
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2a
chr3_+_45375580 0.23 ENSDART00000162799
crb3a
crumbs homolog 3a
chr16_-_35462083 0.23 ENSDART00000170048
taf12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr7_+_21592861 0.21 ENSDART00000159626
si:dkey-85k7.7
si:dkey-85k7.7
chr21_-_3619164 0.20 ENSDART00000133980
scamp1
secretory carrier membrane protein 1
chr1_-_37452112 0.19 ENSDART00000142811
hmgb2a
high mobility group box 2a
chr16_+_14311271 0.19 ENSDART00000113679
dap3
death associated protein 3
chr5_-_3254995 0.19 ENSDART00000152108
hspb1
heat shock protein, alpha-crystallin-related, 1
chr5_+_60972907 0.15 ENSDART00000134387
ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr8_-_43568078 0.14 ENSDART00000051139
ENSDART00000160289
ncor2
nuclear receptor corepressor 2
chr3_-_23620163 0.12

chr9_+_19707706 0.12 ENSDART00000157395
ENSDART00000102214
ndufv3
NADH dehydrogenase (ubiquinone) flavoprotein 3
chr16_+_34157948 0.11 ENSDART00000140552
tcea3
transcription elongation factor A (SII), 3
chr7_-_18916067 0.11 ENSDART00000112447
il13ra1
interleukin 13 receptor, alpha 1
chr16_-_52090856 0.10 ENSDART00000155308
FO704712.1
ENSDARG00000063300
chr11_+_31295037 0.09 ENSDART00000140204
egln1b
egl-9 family hypoxia-inducible factor 1b
chr11_+_36215690 0.08 ENSDART00000128245
ldlrad2
low density lipoprotein receptor class A domain containing 2
chr13_-_35716712 0.07 ENSDART00000170106
map3k4
mitogen-activated protein kinase kinase kinase 4
chr21_+_30256863 0.07 ENSDART00000007412
zmat2
zinc finger, matrin-type 2
chr15_-_46799699 0.06

chr19_+_43124105 0.05 ENSDART00000136873
clasp2
cytoplasmic linker associated protein 2
chr20_+_29685331 0.02 ENSDART00000153339
adam17b
ADAM metallopeptidase domain 17b
chr3_+_23573053 0.01 ENSDART00000024256
hoxb6a
homeobox B6a
chr19_-_25842461 0.01

chr16_+_10666588 0.01 ENSDART00000091241
si:ch73-22o12.1
si:ch73-22o12.1
chr22_-_8479330 0.00 ENSDART00000140146
ENSDART00000136891
si:ch73-27e22.3
si:ch73-27e22.3
chr8_-_41271615 0.00 ENSDART00000075491
pop5
POP5 homolog, ribonuclease P/MRP subunit

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571) regulation of nuclear cell cycle DNA replication(GO:0033262)
0.8 2.5 GO:0072045 convergent extension involved in nephron morphogenesis(GO:0072045)
0.7 2.7 GO:0046100 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine metabolic process(GO:0046098) guanine biosynthetic process(GO:0046099) hypoxanthine metabolic process(GO:0046100)
0.6 2.5 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.4 8.3 GO:0008354 germ cell migration(GO:0008354)
0.4 1.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.3 1.0 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037)
0.3 0.9 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.3 1.2 GO:0010664 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.2 1.4 GO:0060296 regulation of cilium beat frequency(GO:0003356) regulation of translational termination(GO:0006449) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.2 4.1 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.2 1.0 GO:0046685 regulation of myofibril size(GO:0014881) response to arsenic-containing substance(GO:0046685)
0.2 2.6 GO:0046599 regulation of centriole replication(GO:0046599)
0.2 1.1 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.2 0.7 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.2 0.5 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.2 0.5 GO:1903441 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.2 1.8 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.2 1.3 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.8 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 1.7 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.1 1.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.5 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.1 0.7 GO:0032094 response to food(GO:0032094)
0.1 2.6 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.7 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 1.3 GO:0072091 regulation of stem cell proliferation(GO:0072091)
0.1 3.2 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 0.9 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 1.5 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.4 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.3 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.4 GO:0006517 protein deglycosylation(GO:0006517)
0.0 1.1 GO:0043588 skin development(GO:0043588)
0.0 1.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.6 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 4.5 GO:0016197 endosomal transport(GO:0016197)
0.0 0.7 GO:0060415 muscle tissue morphogenesis(GO:0060415)
0.0 0.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 2.1 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.9 GO:0006414 translational elongation(GO:0006414)
0.0 0.3 GO:0030307 positive regulation of cell growth(GO:0030307)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.2 GO:0031431 Dbf4-dependent protein kinase complex(GO:0031431)
0.7 3.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.6 2.6 GO:0017177 glucosidase II complex(GO:0017177)
0.2 1.7 GO:0005688 U6 snRNP(GO:0005688)
0.2 0.8 GO:0097255 R2TP complex(GO:0097255)
0.1 1.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.7 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 2.4 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 1.9 GO:0005686 U2 snRNP(GO:0005686)
0.1 1.3 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 1.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 1.0 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 1.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.3 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.0 2.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.3 GO:0005811 lipid particle(GO:0005811)
0.0 1.4 GO:0005643 nuclear pore(GO:0005643)
0.0 1.1 GO:0030426 growth cone(GO:0030426)
0.0 1.5 GO:0005871 kinesin complex(GO:0005871)
0.0 1.2 GO:0005814 centriole(GO:0005814)
0.0 1.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.8 GO:0016459 myosin complex(GO:0016459)
0.0 0.9 GO:0030027 lamellipodium(GO:0030027)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0052657 guanine phosphoribosyltransferase activity(GO:0052657)
0.5 2.5 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.5 1.4 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692) cGMP binding(GO:0030553)
0.5 4.1 GO:0008252 nucleotidase activity(GO:0008252)
0.4 8.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.4 2.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 1.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.3 1.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.3 1.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.3 1.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 2.5 GO:0070697 activin receptor binding(GO:0070697)
0.2 1.3 GO:0090624 endoribonuclease activity, cleaving miRNA-paired mRNA(GO:0090624)
0.2 5.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 0.8 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.2 0.7 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.2 2.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.8 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 1.7 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.7 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 1.1 GO:0019894 kinesin binding(GO:0019894)
0.1 1.8 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.1 1.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.7 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 1.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.4 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 3.0 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.5 GO:0030276 clathrin binding(GO:0030276)
0.0 0.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 2.0 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 2.5 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 1.3 GO:0000149 SNARE binding(GO:0000149)
0.0 2.3 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.9 GO:0051082 unfolded protein binding(GO:0051082)
0.0 4.5 GO:0005525 GTP binding(GO:0005525)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3 2.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 2.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 2.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.0 PID MYC PATHWAY C-MYC pathway
0.0 1.1 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.4 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.8 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.2 PID TRAIL PATHWAY TRAIL signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 2.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 2.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.5 REACTOME KINESINS Genes involved in Kinesins
0.1 2.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.7 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.0 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling