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Results for ctcf

Z-value: 2.73

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Transcription factors associated with ctcf

Gene Symbol Gene ID Gene Info
ENSDARG00000056621 CCCTC-binding factor (zinc finger protein)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ctcfdr10_dc_chr18_+_22297247_222972540.821.2e-04Click!

Activity profile of ctcf motif

Sorted Z-values of ctcf motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ctcf

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr9_+_28293831 9.21 ENSDART00000101338
isocitrate dehydrogenase 1 (NADP+), soluble
chr16_-_24727689 9.07 ENSDART00000167121
FXYD domain containing ion transport regulator 6 like
chr14_-_41101660 9.03 ENSDART00000003170
MID1 interacting protein 1, like
chr11_-_25019899 8.70 ENSDART00000123567
snail family zinc finger 1a
chr22_-_28828375 7.84 ENSDART00000104880
ENSDART00000005112
si:dkeyp-34c12.1
chr8_+_37716781 7.73 ENSDART00000108556
nucleophosmin/nucleoplasmin, 2a
chr16_+_28946580 7.03 ENSDART00000146525
chromatin target of PRMT1b
chr25_+_5845303 6.96 ENSDART00000163948
ENSDARG00000053246
chr24_-_33894062 6.61 ENSDART00000079210
cyclin-dependent kinase 5
chr24_-_20999883 5.79 ENSDART00000155652
GRAM domain containing 1c
chr1_+_22160932 5.64 ENSDART00000016488
general transcription factor IIE, polypeptide 2, beta
chr9_-_34459799 5.18 ENSDART00000059955
immunoglobulin-like domain containing receptor 1b
chr24_-_13205000 4.80 ENSDART00000134482
telomeric repeat binding factor (NIMA-interacting) 1
chr14_+_21831841 4.80 ENSDART00000132514
cyclin G1
chr17_+_7377230 4.80 ENSDART00000157123
SNF2 histone linker PHD RING helicase
chr19_+_24483983 4.79 ENSDART00000141351
peroxisomal biogenesis factor 11 beta
chr5_+_40896478 4.75 ENSDART00000039369
Fanconi anemia, complementation group G
chr7_+_15479700 4.64

chr5_-_31173320 4.63 ENSDART00000122066
family with sequence similarity 102, member Ab
chr20_-_35601497 4.56

chr25_-_7526393 4.55

chr5_-_31796734 4.55 ENSDART00000142095
F-box and WD repeat domain containing 2
chr8_-_38284748 4.47 ENSDART00000102233
PDZ and LIM domain 2 (mystique)
chr5_+_53850871 4.42 ENSDART00000158149
transmembrane protein 203
chr12_-_3042394 4.40 ENSDART00000002867
ENSDART00000126315
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr6_-_42390995 4.33 ENSDART00000049425
Sec61 translocon alpha 1 subunit, like
chr19_+_40750511 4.28 ENSDART00000147391
family with sequence similarity 133, member B
chr2_+_24045890 4.27 ENSDART00000047073
oxidative stress responsive 1a
chr12_-_10529153 4.25 ENSDART00000047769
myoferlin
chr6_+_47847753 4.23 ENSDART00000064842
peptidyl arginine deiminase, type II
chr7_-_33965017 4.14

chr1_+_45148002 4.12 ENSDART00000148086
mitogen-activated protein kinase kinase 7
chr20_-_29961498 4.12 ENSDART00000132278
ring finger protein 144ab
chr8_-_38284959 4.00 ENSDART00000125920
PDZ and LIM domain 2 (mystique)
chr14_-_46608307 3.92 ENSDART00000074038
SCY1-like, kinase-like 1
chr12_+_31668126 3.91 ENSDART00000105584
leucine rich repeat containing 59
chr20_-_29961589 3.91 ENSDART00000132278
ring finger protein 144ab
chr6_+_60130111 3.87 ENSDART00000148557
aurora kinase A
chr15_-_4976217 3.86 ENSDART00000101992
lipoyl(octanoyl) transferase 2 (putative)
chr10_+_42111560 3.83 ENSDART00000126248
transmembrane protein 120B
chr2_+_24046083 3.82 ENSDART00000047073
oxidative stress responsive 1a
chr15_+_32053944 3.75 ENSDART00000175828
breast cancer 2, early onset
chr5_+_40896320 3.73 ENSDART00000039369
Fanconi anemia, complementation group G
chr7_+_33965084 3.72 ENSDART00000052474
timeless interacting protein
chr3_-_23919508 3.66 ENSDART00000155896
ENSDARG00000097621
chr12_+_31668168 3.66 ENSDART00000105584
leucine rich repeat containing 59
chr3_+_37648476 3.59 ENSDART00000151506
si:dkey-260c8.8
chr5_-_1604221 3.54 ENSDART00000055878
RNA terminal phosphate cyclase-like 1
chr12_+_18776712 3.52

chr8_+_40236817 3.51 ENSDART00000164414
ORAI calcium release-activated calcium modulator 1a
chr2_-_9946148 3.36 ENSDART00000175460
dishevelled segment polarity protein 3a
chr8_-_38284904 3.29 ENSDART00000125920
PDZ and LIM domain 2 (mystique)
chr6_+_60130210 3.28 ENSDART00000148557
aurora kinase A
chr3_-_29725539 3.24

chr5_-_39598926 3.21 ENSDART00000175588
WD repeat and FYVE domain containing 3
chr3_+_25719002 3.15 ENSDART00000007119
major facilitator superfamily domain containing 6-like
chr14_-_35932521 3.14 ENSDART00000158722
ENSDARG00000101064
chr5_-_55082078 3.12 ENSDART00000097424
potassium channel modulatory factor 1
chr5_+_53851006 3.08 ENSDART00000157722
ENSDART00000160446
transmembrane protein 203
chr13_+_35402766 3.08 ENSDART00000163368
ENSDART00000075414
ENSDART00000112947
WD repeat domain 27
chr6_-_41031013 3.06 ENSDART00000134293
TruB pseudouridine (psi) synthase family member 2
chr8_+_13327234 3.03 ENSDART00000159760
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr12_-_7604946 3.03 ENSDART00000126712
coiled-coil domain containing 6b
chr5_-_28914505 3.03 ENSDART00000098364
euchromatic histone-lysine N-methyltransferase 1a
chr12_+_23870379 3.02 ENSDART00000003143
proteasome activator subunit 4b
chr2_-_42643265 3.01 ENSDART00000009093
extended synaptotagmin-like protein 2a
chr9_-_34459768 3.00 ENSDART00000059955
immunoglobulin-like domain containing receptor 1b
chr5_-_55081799 2.92 ENSDART00000158102
potassium channel modulatory factor 1
chr20_+_26103308 2.87 ENSDART00000147845
nuclear receptor binding protein 1
chr6_+_41031160 2.84

chr8_-_51967969 2.81 ENSDART00000057315
centrosomal protein 78
chr12_-_48391342 2.81 ENSDART00000153209
DnaJ (Hsp40) homolog, subfamily B, member 12b
chr8_+_21405821 2.80 ENSDART00000142758
si:dkey-163f12.10
chr5_+_61279071 2.74 ENSDART00000168808
si:dkeyp-117b8.4
chr21_-_30387895 2.73

chr21_-_21787648 2.71 ENSDART00000030984
WD repeat domain 73
chr18_-_40763266 2.71 ENSDART00000130397
v-akt murine thymoma viral oncogene homolog 2
chr21_+_6008781 2.68 ENSDART00000141607
folylpolyglutamate synthase
chr17_+_33205732 2.68 ENSDART00000104476
sorting nexin 9a
chr23_-_14118530 2.65 ENSDART00000139406
glucose-6-phosphate dehydrogenase
chr24_-_10756995 2.64 ENSDART00000145593
family with sequence similarity 49, member Bb
chr16_-_42203272 2.64

chr21_-_21787540 2.63 ENSDART00000030984
WD repeat domain 73
chr1_+_21244200 2.63 ENSDART00000087729
lysine (K)-specific demethylase 4C
chr7_-_46940193 2.61 ENSDART00000161558
ENSDARG00000099964
chr10_+_6339059 2.54 ENSDART00000160813
tropomyosin 2 (beta)
chr12_-_18776533 2.52 ENSDART00000163582
desumoylating isopeptidase 1b
chr3_+_37648665 2.51 ENSDART00000151506
si:dkey-260c8.8
chr12_-_3042545 2.46 ENSDART00000002867
ENSDART00000126315
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr8_-_11286437 2.44 ENSDART00000008215
phosphatidylinositol-4-phosphate 5-kinase, type I, beta b
chr8_-_11286308 2.43 ENSDART00000008215
phosphatidylinositol-4-phosphate 5-kinase, type I, beta b
chr9_-_47524405 2.37 ENSDART00000177844
ENSDARG00000099077
chr18_-_40763107 2.33 ENSDART00000130397
v-akt murine thymoma viral oncogene homolog 2
chr6_+_11445252 2.31 ENSDART00000151447
ENSDART00000151618
calcitonin receptor-like b
chr12_+_27498216 2.28 ENSDART00000066288
spermatogenesis associated 20
chr6_+_47847593 2.28 ENSDART00000064842
peptidyl arginine deiminase, type II
chr15_-_43954665 2.27 ENSDART00000041249
cysteine and histidine-rich domain (CHORD) containing 1a
chr24_-_33894123 2.27 ENSDART00000128679
cyclin-dependent kinase 5
chr8_+_25988813 2.23 ENSDART00000058100
xeroderma pigmentosum, complementation group C
chr20_-_34894607 2.23

chr17_-_7377094 2.21

chr22_+_35156074 2.17 ENSDART00000130581
ring finger protein 13
chr8_-_34509255 2.17 ENSDART00000112854
GTPase activating protein and VPS9 domains 1
chr19_+_24484213 2.15 ENSDART00000100420
peroxisomal biogenesis factor 11 beta
chr17_+_31605159 2.15 ENSDART00000157148
cyclin-dependent kinase 2 interacting protein
chr22_-_28828300 2.15 ENSDART00000104880
si:dkeyp-34c12.1
chr3_+_29380031 2.14 ENSDART00000123619
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr11_+_22462697 2.12 ENSDART00000111850
si:ch211-86h15.1
chr14_-_31375046 2.10 ENSDART00000173274
MAP7 domain containing 3
chr8_-_11164322 2.09 ENSDART00000147817
family with sequence similarity 208, member B
chr5_-_9443859 2.09

chr4_-_70894359 2.07 ENSDART00000160796
zgc:175107
chr21_-_21477462 2.06 ENSDART00000031205
poliovirus receptor-related 3b
chr1_-_53258987 2.05 ENSDART00000032552
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr12_-_7604882 2.05 ENSDART00000126219
coiled-coil domain containing 6b
chr12_-_17370920 2.05 ENSDART00000130735
multiple inositol-polyphosphate phosphatase 1b
chr23_-_19560269 2.04 ENSDART00000009092
family with sequence similarity 208, member Ab
chr18_+_35253987 2.03 ENSDART00000129624
transforming growth factor beta regulator 1
chr16_+_40390419 2.03 ENSDART00000102571
methyltransferase like 6
chr17_-_10342212 2.02 ENSDART00000171324
mirror-image polydactyly 1
chr6_+_19933322 2.02 ENSDART00000143378
THUMP domain containing 3
chr14_-_46608393 1.96 ENSDART00000074038
SCY1-like, kinase-like 1
chr12_-_3042573 1.95 ENSDART00000002867
ENSDART00000126315
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr5_+_61278798 1.94 ENSDART00000168808
si:dkeyp-117b8.4
chr15_-_46864317 1.92

chr1_+_25982964 1.91 ENSDART00000152299
si:dkey-25o16.4
chr3_+_37673971 1.91

chr12_-_33481348 1.90 ENSDART00000009794
ENSDART00000136617
tudor and KH domain containing
chr7_+_66410533 1.84 ENSDART00000027616
ENSDART00000162763
eukaryotic translation initiation factor 4, gamma 2a
chr8_+_21405788 1.83 ENSDART00000142758
si:dkey-163f12.10
chr14_+_8288174 1.83 ENSDART00000037749
syntaxin 5A
chr12_+_23870021 1.83 ENSDART00000153136
proteasome activator subunit 4b
chr12_-_4563094 1.82 ENSDART00000152489
interferon regulatory factor 3
chr8_-_11164610 1.80 ENSDART00000147817
family with sequence similarity 208, member B
chr13_+_4289548 1.79

chr1_+_21244242 1.78 ENSDART00000087729
lysine (K)-specific demethylase 4C
chr5_-_1604380 1.78 ENSDART00000055878
RNA terminal phosphate cyclase-like 1
chr11_+_18856937 1.76

chr18_+_8444064 1.75 ENSDART00000171974
PRP18 pre-mRNA processing factor 18 homolog (yeast)
chr8_-_11286377 1.74 ENSDART00000008215
phosphatidylinositol-4-phosphate 5-kinase, type I, beta b
chr18_+_27018679 1.73 ENSDART00000086131
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
chr13_+_35639263 1.73 ENSDART00000100156
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr9_-_12623750 1.72 ENSDART00000142024
transformer 2 beta homolog
chr5_-_31173039 1.70 ENSDART00000137556
family with sequence similarity 102, member Ab
chr9_-_14302452 1.69 ENSDART00000135458
ATP-binding cassette, sub-family B (MDR/TAP), member 6b
chr22_-_551324 1.68

chr9_-_11683921 1.67 ENSDART00000044314
ENSDART00000124129
integrin, alpha V
chr8_-_11164560 1.67 ENSDART00000147817
family with sequence similarity 208, member B
chr16_+_23884575 1.64 ENSDART00000046922
RAB13, member RAS oncogene family
chr20_+_38555185 1.64 ENSDART00000020153
aarF domain containing kinase 3
chr6_-_32001100 1.63 ENSDART00000132280
receptor tyrosine kinase-like orphan receptor 1
chr7_-_59851075 1.63 ENSDART00000128363
chaperonin containing TCP1, subunit 7 (eta)
chr10_+_6339177 1.63 ENSDART00000160813
tropomyosin 2 (beta)
chr8_+_19589519 1.62 ENSDART00000144667
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3a
chr17_+_22557630 1.61 ENSDART00000045099
Yip1 domain family, member 4
chr7_+_15479520 1.60

chr6_+_38775771 1.57 ENSDART00000129655
ubiquitin protein ligase E3A
chr3_+_14492079 1.56 ENSDART00000091070
zgc:158403
chr8_+_47108614 1.55 ENSDART00000142979
Rho guanine nucleotide exchange factor (GEF) 16
chr8_-_38285034 1.55 ENSDART00000125920
PDZ and LIM domain 2 (mystique)
chr10_-_28230992 1.53 ENSDART00000134491
mediator complex subunit 13a
chr13_+_35639424 1.51 ENSDART00000100156
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr19_-_33687786 1.51 ENSDART00000134045
family with sequence similarity 92, member A1
chr5_+_58446380 1.47 ENSDART00000154978
si:ch211-284f22.3
chr6_+_11445579 1.47 ENSDART00000151447
ENSDART00000151618
calcitonin receptor-like b
chr9_-_11291927 1.46 ENSDART00000113847
chondroitin polymerizing factor a
chr3_-_37006705 1.46 ENSDART00000167544
ENSDART00000055227
MLX, MAX dimerization protein
chr19_-_33687836 1.39 ENSDART00000020301
family with sequence similarity 92, member A1
chr9_+_49121732 1.38 ENSDART00000112555
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr17_+_33205888 1.38 ENSDART00000104476
sorting nexin 9a
chr2_+_24045941 1.35 ENSDART00000047073
oxidative stress responsive 1a
chr6_+_36494804 1.33 ENSDART00000138778
ENSDARG00000094164
chr16_+_12922320 1.28 ENSDART00000008535
U2 small nuclear RNA auxiliary factor 2a
chr13_-_36635434 1.28 ENSDART00000179302
mitogen-activated protein kinase kinase kinase kinase 5
chr4_-_18523472 1.27 ENSDART00000045639
RAD50 interactor 1
chr10_+_6338988 1.27 ENSDART00000160813
tropomyosin 2 (beta)
chr12_-_10529236 1.25 ENSDART00000144283
myoferlin
chr25_-_12838540 1.23 ENSDART00000167362
chemokine (C-C motif) ligand 39, duplicate 7
chr3_+_37673922 1.22

chr14_-_44329331 1.21 ENSDART00000098640
glyoxylate reductase/hydroxypyruvate reductase a
chr19_-_9044008 1.19 ENSDART00000104657
mitochondrial ribosomal protein S21
chr2_+_43355846 1.18 ENSDART00000056402
par-3 family cell polarity regulator alpha, b
chr3_+_25718973 1.17 ENSDART00000007119
major facilitator superfamily domain containing 6-like
chr25_+_28380674 1.16 ENSDART00000067072
nuclear transcription factor Y, beta b
chr6_-_1638631 1.15 ENSDART00000087039
ENSDARG00000015563
chr19_-_7151801 1.15 ENSDART00000176808
TAP binding protein (tapasin), tandem duplicate 1
chr5_+_61278989 1.14 ENSDART00000168808
si:dkeyp-117b8.4
chr24_-_13204960 1.14 ENSDART00000134482
telomeric repeat binding factor (NIMA-interacting) 1
chr19_+_21201360 1.14 ENSDART00000038942
ADNP homeobox 2b
chr14_-_44329409 1.14 ENSDART00000098640
glyoxylate reductase/hydroxypyruvate reductase a
chr8_+_27788761 1.09 ENSDART00000170037
capping protein (actin filament) muscle Z-line, alpha 1b
chr13_+_35402382 1.09 ENSDART00000163368
WD repeat domain 27
chr9_-_14302373 1.09 ENSDART00000135458
ATP-binding cassette, sub-family B (MDR/TAP), member 6b
chr7_+_30454112 1.09 ENSDART00000085716
myotubularin related protein 10
chr18_+_35254188 1.08 ENSDART00000129624
transforming growth factor beta regulator 1
chr2_-_42643138 1.07 ENSDART00000009093
extended synaptotagmin-like protein 2a
chr1_+_58224772 1.06 ENSDART00000159479
ENSDART00000163871
thyroid hormone receptor interactor 10b
chr6_-_37771729 1.06 ENSDART00000078324
non imprinted in Prader-Willi/Angelman syndrome 1
chr10_-_25755035 1.03 ENSDART00000140483
SR-related CTD-associated factor 4a
chr14_+_31133551 1.01 ENSDART00000173088
coiled-coil domain containing 160

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.2 GO:0006097 glyoxylate cycle(GO:0006097)
2.3 6.9 GO:0044375 regulation of peroxisome size(GO:0044375)
1.6 6.5 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
1.6 4.8 GO:0007289 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
1.4 7.2 GO:0000212 meiotic spindle organization(GO:0000212)
1.3 8.9 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
1.2 4.7 GO:0046326 positive regulation of glucose import(GO:0046326)
1.1 4.3 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.9 3.7 GO:0043111 replication fork arrest(GO:0043111)
0.9 8.8 GO:0035283 fourth ventricle development(GO:0021592) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.7 4.2 GO:0009249 protein lipoylation(GO:0009249)
0.6 3.8 GO:0045444 fat cell differentiation(GO:0045444)
0.6 1.9 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.6 3.9 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.5 1.6 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.5 3.7 GO:0008585 female gonad development(GO:0008585)
0.5 9.1 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.5 8.2 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.4 7.6 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579) positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.4 1.8 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.4 4.3 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.4 5.3 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.3 5.6 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.3 8.5 GO:0036297 interstrand cross-link repair(GO:0036297)
0.3 1.2 GO:0051660 establishment of centrosome localization(GO:0051660)
0.3 8.7 GO:0008078 mesodermal cell migration(GO:0008078)
0.3 3.0 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.3 6.5 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.3 3.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.2 1.2 GO:0034341 monocyte chemotaxis(GO:0002548) response to interferon-gamma(GO:0034341) cellular response to interferon-gamma(GO:0071346)
0.2 1.0 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2 0.9 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.2 9.0 GO:0046890 regulation of lipid biosynthetic process(GO:0046890)
0.2 1.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.2 3.1 GO:0001522 pseudouridine synthesis(GO:0001522)
0.2 1.1 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 2.1 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.2 0.7 GO:0031120 snRNA pseudouridine synthesis(GO:0031120) mRNA pseudouridine synthesis(GO:1990481)
0.2 0.5 GO:0045190 B cell activation involved in immune response(GO:0002312) histone H2B ubiquitination(GO:0033523) isotype switching(GO:0045190)
0.2 5.5 GO:0007520 myoblast fusion(GO:0007520)
0.2 2.8 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.2 2.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 2.2 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 1.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.6 GO:0051299 mitotic centrosome separation(GO:0007100) centrosome separation(GO:0051299)
0.1 2.8 GO:0051788 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.1 6.0 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.1 2.6 GO:0050870 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.1 0.4 GO:0072672 neutrophil homeostasis(GO:0001780) neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.1 1.3 GO:0046660 female sex differentiation(GO:0046660)
0.1 5.6 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 0.5 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 1.5 GO:0006298 mismatch repair(GO:0006298)
0.1 10.8 GO:0006338 chromatin remodeling(GO:0006338)
0.1 0.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 1.1 GO:0015693 magnesium ion transport(GO:0015693)
0.1 4.8 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 1.0 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.1 0.8 GO:0034311 diol metabolic process(GO:0034311)
0.1 2.1 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 4.7 GO:0006334 nucleosome assembly(GO:0006334)
0.1 2.8 GO:0051298 centrosome duplication(GO:0051298)
0.1 1.3 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.1 3.0 GO:0098661 inorganic anion transmembrane transport(GO:0098661)
0.1 3.4 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.1 2.0 GO:0030488 tRNA methylation(GO:0030488)
0.1 1.6 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.1 5.4 GO:0006936 muscle contraction(GO:0006936)
0.1 6.6 GO:0006874 cellular calcium ion homeostasis(GO:0006874)
0.1 0.7 GO:0090148 membrane fission(GO:0090148)
0.1 7.7 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 4.7 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 1.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 2.4 GO:0034968 histone lysine methylation(GO:0034968)
0.0 1.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 1.7 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.5 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 2.3 GO:0070646 protein modification by small protein removal(GO:0070646)
0.0 2.1 GO:0006413 translational initiation(GO:0006413)
0.0 3.0 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 6.4 GO:0061061 muscle structure development(GO:0061061)
0.0 0.7 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.9 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 2.3 GO:0006869 lipid transport(GO:0006869)
0.0 2.0 GO:0032259 methylation(GO:0032259)
0.0 4.2 GO:0006511 ubiquitin-dependent protein catabolic process(GO:0006511)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0031298 replication fork protection complex(GO:0031298)
1.2 7.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.9 8.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.8 6.9 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.6 4.3 GO:0005784 Sec61 translocon complex(GO:0005784)
0.6 1.8 GO:0071020 post-spliceosomal complex(GO:0071020)
0.5 6.5 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.4 14.5 GO:0031941 filamentous actin(GO:0031941)
0.3 1.4 GO:0031262 Ndc80 complex(GO:0031262)
0.3 2.1 GO:0030914 STAGA complex(GO:0030914)
0.3 1.0 GO:0019185 snRNA-activating protein complex(GO:0019185)
0.2 1.6 GO:0016328 lateral plasma membrane(GO:0016328) insulin-responsive compartment(GO:0032593)
0.2 0.6 GO:0005871 kinesin complex(GO:0005871)
0.2 1.3 GO:0089701 U2AF(GO:0089701)
0.2 5.4 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 0.7 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 1.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 2.2 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.1 1.6 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 3.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 8.4 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 0.4 GO:0097433 dense body(GO:0097433)
0.1 4.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 6.4 GO:0000502 proteasome complex(GO:0000502)
0.1 1.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 5.3 GO:0000922 spindle pole(GO:0000922)
0.1 5.8 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 5.4 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.1 2.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 2.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 4.7 GO:0000786 nucleosome(GO:0000786)
0.0 1.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 9.3 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 1.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.8 GO:0031201 SNARE complex(GO:0031201)
0.0 5.4 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 3.4 GO:0005635 nuclear envelope(GO:0005635)
0.0 6.2 GO:0005874 microtubule(GO:0005874)
0.0 0.4 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 6.7 GO:0005730 nucleolus(GO:0005730)
0.0 1.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 2.4 GO:0005681 spliceosomal complex(GO:0005681)
0.0 3.8 GO:0015630 microtubule cytoskeleton(GO:0015630)
0.0 0.1 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 8.8 GO:0005783 endoplasmic reticulum(GO:0005783)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.2 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
2.4 7.2 GO:0035174 histone serine kinase activity(GO:0035174)
2.2 8.9 GO:0035173 histone kinase activity(GO:0035173)
2.2 8.8 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
2.0 5.9 GO:0071532 ankyrin repeat binding(GO:0071532)
1.7 8.7 GO:0051059 NF-kappaB binding(GO:0051059)
1.6 6.5 GO:0004668 protein-arginine deiminase activity(GO:0004668)
1.4 4.2 GO:0016415 octanoyltransferase activity(GO:0016415)
1.1 3.4 GO:0097642 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635) calcitonin receptor activity(GO:0004948) calcitonin family receptor activity(GO:0097642)
1.1 4.3 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326)
1.0 3.0 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.8 9.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.8 2.4 GO:0008465 glycerate dehydrogenase activity(GO:0008465)
0.7 4.8 GO:0016504 peptidase activator activity(GO:0016504)
0.7 14.5 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.7 2.0 GO:0034417 bisphosphoglycerate 3-phosphatase activity(GO:0034417)
0.6 3.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.5 3.4 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.4 4.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.4 2.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.4 1.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729) CCR5 chemokine receptor binding(GO:0031730)
0.3 9.4 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.3 1.5 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.3 3.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.3 2.1 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.2 8.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 2.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 4.3 GO:0022884 protein transmembrane transporter activity(GO:0008320) macromolecule transmembrane transporter activity(GO:0022884)
0.2 3.0 GO:0002039 p53 binding(GO:0002039)
0.2 1.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 2.8 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 2.0 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 1.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 3.0 GO:0015370 solute:sodium symporter activity(GO:0015370)
0.1 0.4 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 3.9 GO:0005109 frizzled binding(GO:0005109)
0.1 5.6 GO:0004521 endoribonuclease activity(GO:0004521)
0.1 4.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 2.2 GO:0003684 damaged DNA binding(GO:0003684)
0.1 2.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.4 GO:0032977 membrane insertase activity(GO:0032977)
0.0 10.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.1 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 6.4 GO:0042393 histone binding(GO:0042393)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 15.5 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 2.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.6 GO:0019902 phosphatase binding(GO:0019902)
0.0 3.0 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 6.5 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.7 GO:0003724 RNA helicase activity(GO:0003724)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 12.3 PID REELIN PATHWAY Reelin signaling pathway
0.4 4.7 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.3 7.2 PID AURORA A PATHWAY Aurora A signaling
0.3 7.5 PID ATR PATHWAY ATR signaling pathway
0.2 7.7 PID BARD1 PATHWAY BARD1 signaling events
0.2 8.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 6.0 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 4.8 PID P53 REGULATION PATHWAY p53 pathway
0.1 2.8 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.1 4.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 PID ATM PATHWAY ATM pathway
0.0 0.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.3 PID TNF PATHWAY TNF receptor signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 8.9 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.8 4.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.8 9.2 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.6 12.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.6 8.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.3 1.8 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.3 5.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 2.8 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 6.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2 3.4 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.2 6.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 2.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 3.0 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 5.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 1.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 7.2 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 4.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 0.5 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.5 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.9 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 1.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation