ISMARA results: ctcf

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Results for ctcf

Z-value: 2.73

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Transcription factors associated with ctcf

Gene Symbol	Gene ID	Gene Info
ctcf NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000056621	CCCTC-binding factor (zinc finger protein)

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ctcf	dr10_dc_chr18_+_22297247_22297254	0.82	1.2e-04	Click!

Activity profile of ctcf motif

Sorted Z-values of ctcf motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ctcf

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Promoter	Score	Transcript	Gene	Gene Info
chr9_+_28293831 Show fit	9.21	ENSDART00000101338	idh1 NCBI UniProt ZFIN ENSEMBL Google Show fit	isocitrate dehydrogenase 1 (NADP+), soluble
chr16_-_24727689 Show fit	9.07	ENSDART00000167121	fxyd6l NCBI UniProt ZFIN ENSEMBL Google Show fit	FXYD domain containing ion transport regulator 6 like
chr14_-_41101660 Show fit	9.03	ENSDART00000003170	mid1ip1l NCBI UniProt ZFIN ENSEMBL Google Show fit	MID1 interacting protein 1, like
chr11_-_25019899 Show fit	8.70	ENSDART00000123567	snai1a NCBI UniProt ZFIN ENSEMBL Google Show fit	snail family zinc finger 1a
chr22_-_28828375 Show fit	7.84	ENSDART00000104880 ENSDART00000005112	si:dkeyp-34c12.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-34c12.1
chr8_+_37716781 Show fit	7.73	ENSDART00000108556	npm2a NCBI UniProt ZFIN ENSEMBL Google Show fit	nucleophosmin/nucleoplasmin, 2a
chr16_+_28946580 Show fit	7.03	ENSDART00000146525	chtopb NCBI UniProt ZFIN ENSEMBL Google Show fit	chromatin target of PRMT1b
chr25_+_5845303 Show fit	6.96	ENSDART00000163948	ENSDARG00000053246 NCBI UniProt ZFIN ENSEMBL Google Show fit	ENSDARG00000053246
chr24_-_33894062 Show fit	6.61	ENSDART00000079210	cdk5 NCBI UniProt ZFIN ENSEMBL Google Show fit	cyclin-dependent kinase 5
chr24_-_20999883 Show fit	5.79	ENSDART00000155652	gramd1c NCBI UniProt ZFIN ENSEMBL Google Show fit	GRAM domain containing 1c

Showing 1 to 10 of 200 entries

Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	10.8	GO:0006338	chromatin remodeling(GO:0006338)
3.1	9.2	GO:0006097	glyoxylate cycle(GO:0006097)
0.5	9.1	GO:2000649	regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.2	9.0	GO:0046890	regulation of lipid biosynthetic process(GO:0046890)
1.3	8.9	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.9	8.8	GO:0035283	fourth ventricle development(GO:0021592) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.3	8.7	GO:0008078	mesodermal cell migration(GO:0008078)
0.3	8.5	GO:0036297	interstrand cross-link repair(GO:0036297)
0.5	8.2	GO:0048922	posterior lateral line neuromast deposition(GO:0048922)
0.1	7.7	GO:0046488	phosphatidylinositol metabolic process(GO:0046488)

Showing 1 to 10 of 86 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.4	14.5	GO:0031941	filamentous actin(GO:0031941)
0.0	9.3	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.0	8.8	GO:0005783	endoplasmic reticulum(GO:0005783)
0.9	8.5	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.1	8.4	GO:0030173	integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
1.2	7.2	GO:0031616	spindle pole centrosome(GO:0031616)
0.8	6.9	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	6.7	GO:0005730	nucleolus(GO:0005730)
0.5	6.5	GO:0000783	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.1	6.4	GO:0000502	proteasome complex(GO:0000502)

Showing 1 to 10 of 48 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	15.5	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
0.7	14.5	GO:0051393	muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0	10.4	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.3	9.4	GO:0016307	phosphatidylinositol phosphate kinase activity(GO:0016307)
3.1	9.2	GO:0004450	isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.8	9.1	GO:0017080	sodium channel regulator activity(GO:0017080)
2.2	8.9	GO:0035173	histone kinase activity(GO:0035173)
2.2	8.8	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
1.7	8.7	GO:0051059	NF-kappaB binding(GO:0051059)
0.2	8.3	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)

Showing 1 to 10 of 57 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.5	12.3	PID REELIN PATHWAY	Reelin signaling pathway
0.2	8.8	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.2	7.7	PID BARD1 PATHWAY	BARD1 signaling events
0.3	7.5	PID ATR PATHWAY	ATR signaling pathway
0.3	7.2	PID AURORA A PATHWAY	Aurora A signaling
0.1	6.0	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.1	4.8	PID P53 REGULATION PATHWAY	p53 pathway
0.4	4.7	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.1	4.4	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.1	2.8	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis

Showing 1 to 10 of 13 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.6	12.2	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.8	9.2	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
1.3	8.9	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.6	8.8	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	7.2	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.2	6.5	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.2	6.2	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	5.7	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.3	5.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.8	4.7	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network

Showing 1 to 10 of 26 entries

Results for ctcf

Z-value: 2.73

Motif logo

Transcription factors associated with ctcf

Activity-expression correlation:

Activity profile of ctcf motif

Sorted Z-values of ctcf motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ctcf

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: