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Results for cux1a

Z-value: 0.76

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Transcription factors associated with cux1a

Gene Symbol Gene ID Gene Info
cux1a
ENSDARG00000078459 cut-like homeobox 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
cux1adr10_dc_chr10_-_33212897_33213007-0.674.6e-03Click!

Activity profile of cux1a motif

Sorted Z-values of cux1a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of cux1a

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_+_38898811 1.75 ENSDART00000131347
slc48a1b
solute carrier family 48 (heme transporter), member 1b
chr16_-_39291647 1.62 ENSDART00000171342
tmem42a
transmembrane protein 42a
chr15_-_9443212 1.59 ENSDART00000177158
sacs
sacsin molecular chaperone
chr24_+_41991604 1.57

chr17_-_7635061 1.54 ENSDART00000064655
zbtb2a
zinc finger and BTB domain containing 2a
chr14_-_6738260 1.39 ENSDART00000171792
rufy1
RUN and FYVE domain containing 1
chr6_+_38898605 1.39 ENSDART00000029930
slc48a1b
solute carrier family 48 (heme transporter), member 1b
chr2_+_58943872 1.29 ENSDART00000158860
ENSDART00000067736
stk11
serine/threonine kinase 11
chr21_-_26655258 1.26 ENSDART00000149702
ENSDART00000149840
bscl2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr8_-_29842489 1.19 ENSDART00000149297
slc20a2
solute carrier family 20 (phosphate transporter), member 2
chr19_-_28247275 1.18

chr3_-_36940649 1.05 ENSDART00000110716
ENSDART00000160233
tubg1
tubulin, gamma 1
chr25_-_24440001 1.03 ENSDART00000156805
CR854832.1
ENSDARG00000096817
chr22_+_21491685 0.98 ENSDART00000136374
mier2
mesoderm induction early response 1, family member 2
chr2_-_38223813 0.98 ENSDART00000137395
acin1a
apoptotic chromatin condensation inducer 1a
chr23_-_3778250 0.93 ENSDART00000141682
nudt3a
nudix (nucleoside diphosphate linked moiety X)-type motif 3a
chr2_-_32530224 0.92 ENSDART00000170674
abcf2a
ATP-binding cassette, sub-family F (GCN20), member 2a
chr17_+_22291546 0.88 ENSDART00000151929
ENSDART00000089919
ENSDART00000000804
slc8a1b
solute carrier family 8 (sodium/calcium exchanger), member 1b
chr23_+_3778066 0.87 ENSDART00000141880
smim29
small integral membrane protein 29
chr3_-_30754236 0.87 ENSDART00000109104
suv420h2
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr13_-_4535689 0.82 ENSDART00000023803
c1d
C1D nuclear receptor corepressor
chr16_-_25465777 0.77 ENSDART00000086375
adnp2a
ADNP homeobox 2a
chr21_+_33216466 0.74 ENSDART00000163808
ndst1b
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1b
chr12_+_10078043 0.74 ENSDART00000152369
si:dkeyp-118b1.2
si:dkeyp-118b1.2
chr9_+_42656327 0.73

chr13_-_22831005 0.71 ENSDART00000143112
tspan15
tetraspanin 15
chr21_-_19883010 0.71 ENSDART00000137307
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr3_-_30022268 0.69 ENSDART00000159065
nucb1
nucleobindin 1
chr4_-_30690750 0.64 ENSDART00000160757
CU302413.2
ENSDARG00000107562
chr13_-_22831037 0.63 ENSDART00000057641
tspan15
tetraspanin 15
chr8_+_16722505 0.62 ENSDART00000133514
elovl7a
ELOVL fatty acid elongase 7a
chr11_+_16017857 0.58 ENSDART00000081054
tada3l
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr7_-_56465369 0.56 ENSDART00000020967
csnk2a2a
casein kinase 2, alpha prime polypeptide a
chr7_-_37908695 0.55

chr5_-_26293054 0.55 ENSDART00000126669
lman2lb
lectin, mannose-binding 2-like b
chr2_-_38223766 0.53 ENSDART00000137395
acin1a
apoptotic chromatin condensation inducer 1a
chr8_-_29842274 0.51 ENSDART00000086044
ENSDART00000167487
slc20a2
solute carrier family 20 (phosphate transporter), member 2
chr20_-_38030250 0.48 ENSDART00000142567
angel2
angel homolog 2 (Drosophila)
chr20_-_54285455 0.48 ENSDART00000074255
mgat2
mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr20_-_18836698 0.43 ENSDART00000142837
enpp5
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr3_-_30754325 0.41 ENSDART00000109104
suv420h2
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr23_+_3778116 0.39 ENSDART00000143323
smim29
small integral membrane protein 29
chr3_-_30022354 0.37 ENSDART00000077089
nucb1
nucleobindin 1
chr18_+_45574464 0.33

chr3_-_11861502 0.32 ENSDART00000018159
ENSDARG00000011609
ENSDARG00000011609
chr11_-_16017396 0.30 ENSDART00000081062
arpc4l
actin related protein 2/3 complex, subunit 4, like
chr22_-_25051004 0.29 ENSDART00000131811
csrp2bp
csrp2 binding protein
chr15_+_44514665 0.28

chr18_+_5637539 0.25

chr8_-_29842822 0.25 ENSDART00000149297
slc20a2
solute carrier family 20 (phosphate transporter), member 2
chr16_-_13990964 0.23 ENSDART00000090221
ENSDART00000135099
cdc42ep5
CDC42 effector protein (Rho GTPase binding) 5
KN150232v1_+_13079 0.20 ENSDART00000174701
CABZ01084889.1
ENSDARG00000107269
chr22_-_25051056 0.18 ENSDART00000131811
csrp2bp
csrp2 binding protein
chr2_+_58943688 0.18 ENSDART00000158860
ENSDART00000067736
stk11
serine/threonine kinase 11
chr3_-_11861438 0.17 ENSDART00000018159
ENSDARG00000011609
ENSDARG00000011609
chr25_-_5955137 0.15 ENSDART00000104755
cpeb1a
cytoplasmic polyadenylation element binding protein 1a
chr18_+_44709832 0.14 ENSDART00000131510
b3gnt2l
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2, like
chr15_-_7622212 0.11 ENSDART00000165898
gbe1b
glucan (1,4-alpha-), branching enzyme 1b
chr23_-_3778284 0.09 ENSDART00000141682
nudt3a
nudix (nucleoside diphosphate linked moiety X)-type motif 3a
chr5_+_41396720 0.08 ENSDART00000097580
pigl
phosphatidylinositol glycan anchor biosynthesis, class L
chr21_-_13565401 0.08 ENSDART00000151547
pnpla7a
patatin-like phospholipase domain containing 7a
chr16_+_39292206 0.08 ENSDART00000127319
ENSDART00000102510
zgc:77056
zgc:77056
chr7_+_29592486 0.07 ENSDART00000134068
tln2a
talin 2a
chr7_+_29592666 0.06 ENSDART00000134068
tln2a
talin 2a
chr16_-_24646282 0.06 ENSDART00000126274
si:ch211-79k12.2
si:ch211-79k12.2
chr20_+_32503118 0.04 ENSDART00000018640
snx3
sorting nexin 3
chr3_-_30948297 0.04 ENSDART00000145636
ELOB (1 of many)
elongin B
chr8_-_29842345 0.04 ENSDART00000149297
slc20a2
solute carrier family 20 (phosphate transporter), member 2
chr24_-_37596370 0.03 ENSDART00000162538
cluap1
clusterin associated protein 1
chr10_-_11439269 0.02 ENSDART00000064212
srek1ip1
SREK1-interacting protein 1
chr24_-_3375610 0.01 ENSDART00000132648
nck1b
NCK adaptor protein 1b
chr7_-_56465497 0.01 ENSDART00000020967
csnk2a2a
casein kinase 2, alpha prime polypeptide a
chr7_+_29592358 0.00 ENSDART00000167286
tln2a
talin 2a

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0097009 energy homeostasis(GO:0097009)
0.3 3.1 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.2 0.7 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.2 0.9 GO:0000212 meiotic spindle organization(GO:0000212)
0.1 1.0 GO:0009158 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 2.0 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.9 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.7 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.7 GO:0030210 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210) sulfation(GO:0051923)
0.0 0.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.6 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 1.4 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 0.8 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.4 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.2 GO:0031268 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 1.0 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.5 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 1.3 GO:0072659 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0 1.5 GO:0050684 regulation of mRNA processing(GO:0050684)
0.0 0.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.6 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.8 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 3.1 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.9 GO:0042383 sarcolemma(GO:0042383)
0.0 1.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.1 GO:0015232 heme transporter activity(GO:0015232)
0.2 2.0 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 1.0 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.5 GO:0005537 mannose binding(GO:0005537)
0.1 0.7 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.7 GO:2001069 glycogen binding(GO:2001069)
0.0 0.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 1.5 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 1.0 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.6 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.9 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 0.9 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 2.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi