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DANIO-CODE

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Results for dlx1a

Z-value: 0.81

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Transcription factors associated with dlx1a

Gene Symbol Gene ID Gene Info
dlx1a
ENSDARG00000013125 distal-less homeobox 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
dlx1adr10_dc_chr9_+_3416651_3416654-0.861.8e-05Click!

Activity profile of dlx1a motif

Sorted Z-values of dlx1a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of dlx1a

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr16_-_24727689 2.39 ENSDART00000167121
fxyd6l
FXYD domain containing ion transport regulator 6 like
chr11_-_6442588 2.18 ENSDART00000137879
zgc:162969
zgc:162969
chr18_-_40718244 2.12 ENSDART00000077577
si:ch211-132b12.8
si:ch211-132b12.8
KN150456v1_-_19515 1.97 ENSDART00000168786
h1m
linker histone H1M
chr10_-_21404605 1.92 ENSDART00000125167
avd
avidin
chr6_+_23476669 1.87

chr21_-_32027717 1.69 ENSDART00000131651
ENSDARG00000073961
ENSDARG00000073961
chr17_+_16038358 1.65 ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr14_-_33141111 1.64 ENSDART00000147059
lamp2
lysosomal-associated membrane protein 2
chr3_+_42383724 1.54

chr25_+_5845303 1.47 ENSDART00000163948
ENSDARG00000053246
ENSDARG00000053246
chr12_-_36046366 1.46

chr19_-_20819477 1.42 ENSDART00000151356
dazl
deleted in azoospermia-like
chr7_+_35163845 1.40 ENSDART00000173733
BX294178.2
ENSDARG00000104955
chr21_+_25740782 1.40 ENSDART00000021620
cldnd
claudin d
chr12_-_33256754 1.40 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr4_+_4825461 1.38 ENSDART00000150309
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr5_+_36168475 1.38 ENSDART00000146854
mark4a
MAP/microtubule affinity-regulating kinase 4a
chr19_-_20819101 1.35 ENSDART00000137590
dazl
deleted in azoospermia-like
chr24_+_19270877 1.33

chr21_+_20360180 1.31 ENSDART00000003299
ENSDARG00000025174
ENSDARG00000025174
chr11_-_44539778 1.31 ENSDART00000161846
map1lc3c
microtubule-associated protein 1 light chain 3 gamma
chr10_+_15066791 1.29 ENSDART00000140084
si:dkey-88l16.5
si:dkey-88l16.5
chr7_-_47978449 1.26 ENSDART00000127007
ENSDART00000024062
cpeb1b
cytoplasmic polyadenylation element binding protein 1b
chr16_+_42567707 1.26 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr11_-_1524107 1.25 ENSDART00000110097
si:ch73-303b9.1
si:ch73-303b9.1
chr1_+_46474561 1.24 ENSDART00000167051
cbr1
carbonyl reductase 1
chr20_-_14218080 1.21 ENSDART00000104032
si:ch211-223m11.2
si:ch211-223m11.2
chr14_+_22159893 1.21 ENSDART00000019296
gdf9
growth differentiation factor 9
chr10_-_8088063 1.20 ENSDART00000099031
zgc:136254
zgc:136254
chr18_-_43890836 1.18 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr23_+_32174669 1.17 ENSDART00000000992
ENSDARG00000000887
ENSDARG00000000887
KN150030v1_-_22572 1.17 ENSDART00000175410
CABZ01079802.1
ENSDARG00000106760
chr10_-_4641624 1.16 ENSDART00000163951
plppr1
phospholipid phosphatase related 1
chr17_+_16038103 1.16 ENSDART00000155005
si:ch73-204p21.2
si:ch73-204p21.2
chr9_+_29737843 1.10 ENSDART00000176057
rnf17
ring finger protein 17
chr7_-_73613531 1.10 ENSDART00000128137
zgc:92594
zgc:92594
chr22_-_38321005 1.09 ENSDART00000015117
elavl2
ELAV like neuron-specific RNA binding protein 2
chr18_-_38787413 1.07

chr13_+_33578737 1.07 ENSDART00000161465
CABZ01087953.1
ENSDARG00000104106
chr11_-_2437396 1.05

chr8_-_53165501 1.05 ENSDART00000135982
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr19_-_1571878 1.04

chr19_+_5562075 1.04 ENSDART00000148794
jupb
junction plakoglobin b
chr11_+_17849608 1.03 ENSDART00000020283
rpusd4
RNA pseudouridylate synthase domain containing 4
chr19_+_770458 1.02 ENSDART00000062518
gstr
glutathione S-transferase rho
chr18_+_9755131 1.01

chr22_+_17235696 1.01 ENSDART00000134798
tdrd5
tudor domain containing 5
chr21_+_6289363 1.00 ENSDART00000138600
si:ch211-225g23.1
si:ch211-225g23.1
chr6_-_40715613 0.99 ENSDART00000153702
si:ch211-157b11.12
si:ch211-157b11.12
chr7_-_48394268 0.99 ENSDART00000006378
cdkn1ca
cyclin-dependent kinase inhibitor 1Ca
chr6_+_54672873 0.99 ENSDART00000074602
smpd2b
sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase)
chr4_+_71390178 0.98 ENSDART00000174128
zgc:152938
zgc:152938
chr17_-_7575628 0.97 ENSDART00000064657
stx11a
syntaxin 11a
chr6_-_10676857 0.97 ENSDART00000036456
cycsb
cytochrome c, somatic b
KN150266v1_-_68652 0.97

chr12_+_22459177 0.96 ENSDART00000171725
capgb
capping protein (actin filament), gelsolin-like b
chr1_-_51075777 0.94 ENSDART00000152745
snrpb2
small nuclear ribonucleoprotein polypeptide B2
chr13_-_28653891 0.93 ENSDART00000007741
ENSDARG00000013581
ENSDARG00000013581
chr1_-_22617455 0.93 ENSDART00000137567
smim14
small integral membrane protein 14
chr10_+_44853207 0.92 ENSDART00000169466
scarb1
scavenger receptor class B, member 1
chr25_+_29219342 0.91 ENSDART00000108692
ENSDART00000077445
pim3
Pim-3 proto-oncogene, serine/threonine kinase
chr12_+_23691261 0.91 ENSDART00000066331
svila
supervillin a
chr13_-_18564182 0.91 ENSDART00000176809
sfxn3
sideroflexin 3
chr21_-_2273151 0.91 ENSDART00000168712
si:ch73-299h12.6
si:ch73-299h12.6
chr8_+_41003546 0.91 ENSDART00000129344
gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr12_-_33256671 0.90 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr1_+_9443056 0.90 ENSDART00000110698
rbm46
RNA binding motif protein 46
chr11_+_11319810 0.89 ENSDART00000162486
si:dkey-23f9.4
si:dkey-23f9.4
chr16_-_43061368 0.89 ENSDART00000113714
mtx1a
metaxin 1a
chr14_-_8634381 0.89 ENSDART00000129030
zgc:153681
zgc:153681
chr20_+_14218237 0.88 ENSDART00000044937
kcns3b
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3b
chr22_+_1837102 0.87 ENSDART00000163288
znf1174
zinc finger protein 1174
chr24_-_14446593 0.87

chr11_+_44002664 0.87

chr23_-_35691369 0.87 ENSDART00000142369
mfsd5
major facilitator superfamily domain containing 5
chr23_-_25853364 0.87 ENSDART00000110670
ENSDARG00000078574
ENSDARG00000078574
chr1_+_43471798 0.86 ENSDART00000166324
ctnnd1
catenin (cadherin-associated protein), delta 1
chr8_+_16641127 0.86 ENSDART00000076586
si:ch211-198n5.11
si:ch211-198n5.11
chr12_+_22459218 0.85 ENSDART00000171725
capgb
capping protein (actin filament), gelsolin-like b
chr11_+_25302180 0.83 ENSDART00000035602
cxxc1b
CXXC finger protein 1b
chr23_+_22857958 0.83 ENSDART00000111345
rerea
arginine-glutamic acid dipeptide (RE) repeats a
chr12_+_23691397 0.83 ENSDART00000066331
svila
supervillin a
chr21_-_45323151 0.82 ENSDART00000151106
ENSDARG00000053404
ENSDARG00000053404
chr13_-_10214396 0.82 ENSDART00000132231
AL929457.1
ENSDARG00000095483
chr9_+_45193290 0.81 ENSDART00000176175
retsatl
retinol saturase (all-trans-retinol 13,14-reductase) like
chr2_-_40067309 0.81

chr1_+_8468971 0.81 ENSDART00000081343
plk1
polo-like kinase 1 (Drosophila)
chr3_-_61258158 0.79 ENSDART00000123388
baiap2l1b
BAI1-associated protein 2-like 1b
chr7_-_21571924 0.79 ENSDART00000166446
BX005336.1
ENSDARG00000102693
chr4_-_3340315 0.78 ENSDART00000009076
pik3cg
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr16_+_27837465 0.78

chr14_+_15845853 0.78 ENSDART00000160973
polr1a
polymerase (RNA) I polypeptide A
chr13_-_37340209 0.78

chr12_-_33257026 0.78 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr6_+_18941135 0.78 ENSDART00000044519
cx44.2
connexin 44.2
chr3_+_12087549 0.77

chr3_-_30955799 0.77 ENSDART00000103421
zgc:153292
zgc:153292
chr3_-_39912816 0.77 ENSDART00000102540
llgl1
lethal giant larvae homolog 1 (Drosophila)
chr1_+_43471683 0.77 ENSDART00000166324
ctnnd1
catenin (cadherin-associated protein), delta 1
chr9_-_705001 0.77 ENSDART00000147092
cflarb
CASP8 and FADD-like apoptosis regulator b
chr21_-_11562388 0.76 ENSDART00000139289
cast
calpastatin
chr12_+_4885307 0.76 ENSDART00000171525
ENSDART00000159986
plekhm1
pleckstrin homology domain containing, family M (with RUN domain) member 1
chr10_-_17214368 0.76

chr17_-_36913213 0.76 ENSDART00000154981
senp6b
SUMO1/sentrin specific peptidase 6b
chr2_-_15656155 0.75 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr7_+_66660882 0.75 ENSDART00000082664
sbf2
SET binding factor 2
chr18_+_8954512 0.75 ENSDART00000134827
tmem243a
transmembrane protein 243, mitochondrial a
chr2_+_15379961 0.75 ENSDART00000058484
cnn3b
calponin 3, acidic b
chr14_-_15777250 0.75 ENSDART00000165656
mxd3
MAX dimerization protein 3
chr12_+_33257120 0.74

chr11_+_12754166 0.74 ENSDART00000123445
ENSDART00000163364
ENSDART00000066122
rtel1
regulator of telomere elongation helicase 1
chr21_+_11686037 0.74 ENSDART00000031786
glrx
glutaredoxin (thioltransferase)
chr18_-_23847340 0.74 ENSDART00000155068
BX936364.1
ENSDARG00000097764
chr14_+_17092009 0.73 ENSDART00000129838
rnf212
ring finger protein 212
chr20_-_20370323 0.73 ENSDART00000009356
ppp2r5ea
protein phosphatase 2, regulatory subunit B', epsilon isoform a
chr7_-_73613763 0.72 ENSDART00000128137
zgc:92594
zgc:92594
chr11_-_33605979 0.72 ENSDART00000171439
si:ch211-227n13.3
si:ch211-227n13.3
chr6_-_8156471 0.72 ENSDART00000081561
ilf3a
interleukin enhancer binding factor 3a
chr2_+_30800532 0.72

chr22_-_29695242 0.72

chr15_+_35076414 0.71 ENSDART00000165210
zgc:66024
zgc:66024
chr2_-_56848527 0.71 ENSDART00000164330
CU634008.1
ENSDARG00000100430
chr10_-_35313462 0.71 ENSDART00000139107
prr11
proline rich 11
chr7_+_15059782 0.71 ENSDART00000165683
mespba
mesoderm posterior ba
chr5_-_4483970 0.70

chr2_+_56534374 0.70 ENSDART00000113964
POLR2E (1 of many)
RNA polymerase II subunit E
chr25_-_20932941 0.70 ENSDART00000138985
ENSDART00000046298
gnaia
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr8_-_44247277 0.69

chr12_-_33256934 0.69 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr6_-_12687107 0.68 ENSDART00000155360
CU639412.1
ENSDARG00000096929
chr11_-_11809024 0.68 ENSDART00000011657
cdc6
cell division cycle 6 homolog (S. cerevisiae)
chr15_+_29207125 0.67 ENSDART00000060034
zgc:113149
zgc:113149
chr23_+_44814692 0.67

chr1_+_43471754 0.67 ENSDART00000166324
ctnnd1
catenin (cadherin-associated protein), delta 1
chr13_+_20393886 0.66 ENSDART00000081385
ccdc172
coiled-coil domain containing 172
chr23_+_44814525 0.66

chr16_+_25381315 0.66 ENSDART00000114528
tbc1d31
TBC1 domain family, member 31
chr11_-_2437361 0.66

KN150030v1_-_22613 0.66 ENSDART00000175410
CABZ01079802.1
ENSDARG00000106760
chr25_-_8026912 0.65

chr8_-_19215929 0.65 ENSDART00000147172
abhd17ab
abhydrolase domain containing 17Ab
chr11_+_25302072 0.65 ENSDART00000035602
cxxc1b
CXXC finger protein 1b
chr25_-_36616544 0.65

chr6_+_342822 0.65

chr14_-_16118942 0.64

chr8_-_23591293 0.64 ENSDART00000025024
slc38a5b
solute carrier family 38, member 5b
chr18_+_18011759 0.63 ENSDART00000147797
ENSDARG00000011498
ENSDARG00000011498
chr7_-_5253629 0.63 ENSDART00000033316
vangl2
VANGL planar cell polarity protein 2
chr25_-_13394261 0.63 ENSDART00000056721
ldhd
lactate dehydrogenase D
chr5_-_38570658 0.63 ENSDART00000020808
paqr3a
progestin and adipoQ receptor family member IIIa
chr15_-_43402935 0.63 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr20_+_6545449 0.62 ENSDART00000145763
si:ch211-191a24.4
si:ch211-191a24.4
chr20_-_44377905 0.62 ENSDART00000177089
ENSDART00000176887
CABZ01035100.1
ENSDARG00000106328
chr17_-_26519469 0.62 ENSDART00000155692
ccser2a
coiled-coil serine-rich protein 2a
chr21_-_39132388 0.61 ENSDART00000065143
unc119b
unc-119 homolog b (C. elegans)
chr8_-_22252628 0.61 ENSDART00000121513
nphp4
nephronophthisis 4
chr15_+_29460803 0.61 ENSDART00000155198
gdpd5b
glycerophosphodiester phosphodiesterase domain containing 5b
chr1_+_51998406 0.61 ENSDART00000134658
slc44a1a
solute carrier family 44 (choline transporter), member 1a
chr6_+_18941186 0.61 ENSDART00000044519
cx44.2
connexin 44.2
chr7_-_54752916 0.61

chr18_+_39506453 0.60 ENSDART00000126978
acadl
acyl-CoA dehydrogenase, long chain
chr21_-_2273243 0.60 ENSDART00000168712
si:ch73-299h12.6
si:ch73-299h12.6
chr3_+_52290252 0.60 ENSDART00000018908
slc27a1a
solute carrier family 27 (fatty acid transporter), member 1a
chr4_+_5147577 0.60 ENSDART00000067392
tigarb
tp53-induced glycolysis and apoptosis regulator b
chr20_+_29306863 0.59 ENSDART00000141252
katnbl1
katanin p80 subunit B-like 1
chr12_+_4885394 0.59 ENSDART00000159367
plekhm1
pleckstrin homology domain containing, family M (with RUN domain) member 1
chr10_+_35313772 0.59 ENSDART00000028940
styxl1
serine/threonine/tyrosine interacting-like 1
chr13_-_30741976 0.59 ENSDART00000142535
CR762493.1
ENSDARG00000092411
chr18_-_23847383 0.59 ENSDART00000155068
BX936364.1
ENSDARG00000097764
chr23_+_44635770 0.59

chr20_-_37910887 0.59 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr10_+_15066970 0.59 ENSDART00000140084
si:dkey-88l16.5
si:dkey-88l16.5
chr8_-_39788989 0.59 ENSDART00000067843
zgc:162025
zgc:162025
chr7_-_73016194 0.58

chr19_+_770644 0.58 ENSDART00000150926
gstr
glutathione S-transferase rho
chr8_+_28362546 0.58 ENSDART00000062682
adipor1b
adiponectin receptor 1b
chr23_-_19299279 0.58 ENSDART00000080099
oard1
O-acyl-ADP-ribose deacylase 1
chr2_+_15379717 0.57 ENSDART00000058484
cnn3b
calponin 3, acidic b
chr23_-_32173435 0.57 ENSDART00000044658
letmd1
LETM1 domain containing 1
chr18_+_5066229 0.57 ENSDART00000157671
CABZ01080599.1
ENSDARG00000100626
chr7_-_21572054 0.57 ENSDART00000166446
BX005336.1
ENSDARG00000102693
chr12_-_33256599 0.57 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr3_-_26052785 0.57 ENSDART00000147517
si:ch211-11k18.4
si:ch211-11k18.4
chr25_-_20933145 0.57 ENSDART00000138985
ENSDART00000046298
gnaia
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr16_+_42567668 0.57 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr2_-_26941084 0.56 ENSDART00000134685
ENSDART00000056787
zgc:113691
zgc:113691
chr1_-_55195566 0.56 ENSDART00000019936
prkacab
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b
chr2_-_47612319 0.56 ENSDART00000133615
BX085193.1
ENSDARG00000091979
chr10_+_15066654 0.56 ENSDART00000135667
si:dkey-88l16.5
si:dkey-88l16.5
chr6_+_49724436 0.56 ENSDART00000154738
stx16
syntaxin 16
chr15_+_23592828 0.56 ENSDART00000152422
si:dkey-182i3.8
si:dkey-182i3.8
chr4_-_14981572 0.55

chr8_+_3364453 0.55 ENSDART00000164426
ctu1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr23_+_22858063 0.55 ENSDART00000111345
rerea
arginine-glutamic acid dipeptide (RE) repeats a
chr21_-_25758145 0.55

chr2_+_15380054 0.55 ENSDART00000058484
cnn3b
calponin 3, acidic b
chr6_+_59580554 0.55

chr24_-_34794538 0.54 ENSDART00000171009
ENSDART00000170046
ctnna1
catenin (cadherin-associated protein), alpha 1
chr9_+_22846082 0.54 ENSDART00000139270
si:dkey-189g17.2
si:dkey-189g17.2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.6 GO:0060967 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.4 1.3 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.3 1.3 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.2 0.7 GO:0090656 t-circle formation(GO:0090656)
0.2 1.4 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 1.2 GO:0030237 female sex determination(GO:0030237)
0.2 0.6 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.2 0.6 GO:0045813 positive regulation of Wnt signaling pathway, calcium modulating pathway(GO:0045813)
0.2 1.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 1.1 GO:2001287 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.2 2.0 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.2 1.1 GO:0006552 leucine catabolic process(GO:0006552)
0.2 1.4 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.2 0.7 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.2 3.9 GO:0051014 actin filament severing(GO:0051014)
0.2 0.3 GO:1902224 cellular ketone body metabolic process(GO:0046950) ketone body metabolic process(GO:1902224)
0.2 0.5 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.2 0.5 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 1.2 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.2 0.6 GO:0042373 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) vitamin K metabolic process(GO:0042373)
0.2 0.6 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.2 0.5 GO:0019563 glycerol catabolic process(GO:0019563)
0.1 0.6 GO:0045980 negative regulation of nucleotide metabolic process(GO:0045980) negative regulation of purine nucleotide metabolic process(GO:1900543)
0.1 1.3 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 0.3 GO:1903726 negative regulation of phospholipid metabolic process(GO:1903726)
0.1 0.8 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1 1.4 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.1 2.4 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 1.3 GO:0009303 rRNA transcription(GO:0009303)
0.1 1.1 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 0.3 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.1 1.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.4 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.6 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.1 0.7 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.8 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.4 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.1 0.4 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.3 GO:0006531 aspartate metabolic process(GO:0006531)
0.1 0.8 GO:0034381 plasma lipoprotein particle clearance(GO:0034381)
0.1 0.6 GO:0097065 anterior head development(GO:0097065)
0.1 4.3 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.1 0.3 GO:0021547 midbrain-hindbrain boundary initiation(GO:0021547)
0.1 0.9 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.6 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 2.3 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 0.2 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.1 0.3 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803) regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544)
0.1 0.5 GO:0034063 stress granule assembly(GO:0034063)
0.1 2.0 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.8 GO:0072178 pronephric duct morphogenesis(GO:0039023) nephric duct morphogenesis(GO:0072178)
0.1 0.4 GO:1901908 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.8 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.2 GO:0009202 deoxyribonucleoside triphosphate biosynthetic process(GO:0009202)
0.1 0.4 GO:2000095 protein localization to ciliary transition zone(GO:1904491) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 1.4 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 0.2 GO:0070126 mitochondrial translational termination(GO:0070126)
0.1 0.2 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.1 0.3 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.1 0.2 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 0.2 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 0.5 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 0.2 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 0.8 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626) regulation of cellular response to insulin stimulus(GO:1900076)
0.1 0.3 GO:0034367 macromolecular complex remodeling(GO:0034367)
0.1 0.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 1.0 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.3 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.2 GO:0035268 protein mannosylation(GO:0035268) mannosylation(GO:0097502)
0.0 0.8 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.3 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.2 GO:0071047 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.0 0.7 GO:0001711 endodermal cell fate commitment(GO:0001711)
0.0 0.8 GO:0001840 neural plate development(GO:0001840)
0.0 0.4 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.2 GO:0051292 pore complex assembly(GO:0046931) nuclear pore complex assembly(GO:0051292)
0.0 0.8 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.7 GO:0007129 synapsis(GO:0007129)
0.0 0.5 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.5 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431) chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 1.9 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.6 GO:0006684 sphingomyelin metabolic process(GO:0006684)
0.0 0.2 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.5 GO:0032418 lysosome localization(GO:0032418)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.2 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.3 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.2 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.4 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.2 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.3 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.1 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.3 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173) inositol phosphate-mediated signaling(GO:0048016)
0.0 0.4 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.3 GO:0046037 GMP biosynthetic process(GO:0006177) GTP biosynthetic process(GO:0006183) GMP metabolic process(GO:0046037)
0.0 0.3 GO:0046349 UDP-N-acetylglucosamine biosynthetic process(GO:0006048) amino sugar biosynthetic process(GO:0046349)
0.0 1.1 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.5 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.3 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.6 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.7 GO:0051607 defense response to virus(GO:0051607)
0.0 0.3 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.1 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.0 0.2 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.3 GO:0051443 protein neddylation(GO:0045116) positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 1.0 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.6 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.8 GO:0009566 single fertilization(GO:0007338) fertilization(GO:0009566)
0.0 0.1 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.0 0.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.4 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.6 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.9 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.2 GO:0060021 palate development(GO:0060021)
0.0 0.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.2 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 0.0 GO:0098751 bone cell development(GO:0098751)
0.0 0.6 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.4 GO:0050708 regulation of protein secretion(GO:0050708)
0.0 0.1 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.9 GO:0051297 centrosome organization(GO:0051297)
0.0 0.5 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.1 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.3 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.2 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.0 GO:0045761 regulation of cAMP metabolic process(GO:0030814) regulation of cAMP biosynthetic process(GO:0030817) regulation of adenylate cyclase activity(GO:0045761)
0.0 0.9 GO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger(GO:0007187) adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.0 0.6 GO:0006865 amino acid transport(GO:0006865)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.4 1.3 GO:0033391 chromatoid body(GO:0033391)
0.4 1.1 GO:1905202 methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.2 1.6 GO:0045171 intercellular bridge(GO:0045171)
0.2 0.5 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.2 0.8 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.9 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 0.6 GO:0002144 cytosolic tRNA wobble base thiouridylase complex(GO:0002144)
0.1 3.2 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.4 GO:0000818 nuclear MIS12/MIND complex(GO:0000818) condensed nuclear chromosome inner kinetochore(GO:0000941)
0.1 1.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.4 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 2.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 1.0 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.9 GO:0070652 HAUS complex(GO:0070652)
0.1 0.4 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 0.7 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.2 GO:0070390 transcription export complex 2(GO:0070390)
0.1 1.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.5 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.2 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.0 0.9 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.5 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.9 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.3 GO:0001650 fibrillar center(GO:0001650)
0.0 1.4 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0097546 ciliary base(GO:0097546)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.9 GO:0031941 filamentous actin(GO:0031941)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.7 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.2 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.6 GO:0005902 microvillus(GO:0005902)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 1.0 GO:0005814 centriole(GO:0005814)
0.0 2.0 GO:0000786 nucleosome(GO:0000786)
0.0 1.4 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.2 GO:0000922 spindle pole(GO:0000922)
0.0 0.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.3 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.9 GO:0031201 SNARE complex(GO:0031201)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.2 GO:0044545 NSL complex(GO:0044545)
0.0 0.1 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.9 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.2 GO:0000177 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.4 1.8 GO:0009374 biotin binding(GO:0009374)
0.3 3.6 GO:0008494 translation activator activity(GO:0008494)
0.3 0.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.3 1.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.3 1.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.2 1.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.2 0.6 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.2 0.6 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.2 1.2 GO:0070698 type I activin receptor binding(GO:0070698)
0.2 0.8 GO:0008410 CoA-transferase activity(GO:0008410)
0.2 0.6 GO:0000403 Y-form DNA binding(GO:0000403) double-strand/single-strand DNA junction binding(GO:0000406) flap-structured DNA binding(GO:0070336)
0.2 1.4 GO:0043295 glutathione binding(GO:0043295)
0.2 1.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 0.5 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.2 0.5 GO:0016844 amine-lyase activity(GO:0016843) strictosidine synthase activity(GO:0016844)
0.2 0.8 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.2 0.6 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.6 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.1 0.6 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.1 1.3 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.4 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 0.4 GO:0047690 aspartyltransferase activity(GO:0047690)
0.1 0.9 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.1 0.4 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.9 GO:0030619 U1 snRNA binding(GO:0030619)
0.1 0.6 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) efflux transmembrane transporter activity(GO:0015562)
0.1 1.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 1.7 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.3 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.1 0.8 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 0.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.8 GO:0045159 myosin II binding(GO:0045159)
0.1 0.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.3 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.9 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.7 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.4 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 0.1 GO:0030623 U5 snRNA binding(GO:0030623)
0.1 0.4 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.5 GO:0005009 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.1 1.7 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679) cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.5 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
0.1 1.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.5 GO:0016849 phosphorus-oxygen lyase activity(GO:0016849)
0.1 0.5 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.5 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 2.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 2.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.7 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 2.5 GO:0045296 cadherin binding(GO:0045296)
0.0 0.8 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.7 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.2 GO:0043878 aminobutyraldehyde dehydrogenase activity(GO:0019145) glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0 0.4 GO:0022829 wide pore channel activity(GO:0022829)
0.0 1.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.5 GO:0017022 myosin binding(GO:0017022)
0.0 0.5 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.2 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.2 GO:0017081 chloride channel regulator activity(GO:0017081) chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0015038 peptide disulfide oxidoreductase activity(GO:0015037) glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 2.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 2.2 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.6 GO:0044325 ion channel binding(GO:0044325)
0.0 0.3 GO:0070840 dynein complex binding(GO:0070840)
0.0 1.4 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.4 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 0.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 4.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 1.2 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.3 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 2.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0043022 ribosome binding(GO:0043022)
0.0 0.0 GO:0000036 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.0 GO:0003874 6-pyruvoyltetrahydropterin synthase activity(GO:0003874)
0.0 0.8 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.4 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.2 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.5 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 1.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.0 PID ATR PATHWAY ATR signaling pathway
0.0 0.7 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.3 PID AURORA A PATHWAY Aurora A signaling
0.0 0.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.3 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 2.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 0.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 0.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.7 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.1 0.7 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 1.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.5 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 1.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.8 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.9 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)