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Results for dlx3b

Z-value: 0.52

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Transcription factors associated with dlx3b

Gene Symbol Gene ID Gene Info
dlx3b
ENSDARG00000014626 distal-less homeobox 3b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
dlx3bdr10_dc_chr12_+_5673442_5673506-0.234.0e-01Click!

Activity profile of dlx3b motif

Sorted Z-values of dlx3b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of dlx3b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr21_-_11562388 0.71 ENSDART00000139289
cast
calpastatin
chr14_+_23420053 0.71 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
KN150266v1_-_68652 0.61

KN150456v1_-_19515 0.56 ENSDART00000168786
h1m
linker histone H1M
chr21_+_25740782 0.54 ENSDART00000021620
cldnd
claudin d
chr24_-_14446593 0.52

chr24_-_23793117 0.51

chr19_-_20819477 0.44 ENSDART00000151356
dazl
deleted in azoospermia-like
chr8_-_31098193 0.44 ENSDART00000098925
vgll4l
vestigial like 4 like
KN150030v1_-_22613 0.43 ENSDART00000175410
CABZ01079802.1
ENSDARG00000106760
chr10_-_2944190 0.43 ENSDART00000132526
marveld2a
MARVEL domain containing 2a
KN150266v1_-_68620 0.42

chr17_+_16038358 0.41 ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr18_-_43890836 0.40 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr5_-_38571198 0.40 ENSDART00000020808
paqr3a
progestin and adipoQ receptor family member IIIa
chr14_+_23419864 0.37 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr8_-_23759076 0.37 ENSDART00000145894
zgc:195245
zgc:195245
chr19_+_39100820 0.34

chr21_-_32747592 0.34

chr14_+_23419894 0.33 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr23_+_22763739 0.31

chr11_-_38856849 0.30 ENSDART00000113185
ap5b1
adaptor-related protein complex 5, beta 1 subunit
chr8_-_31098300 0.30 ENSDART00000098925
vgll4l
vestigial like 4 like
chr19_+_21208954 0.29 ENSDART00000014774
txnl4a
thioredoxin-like 4A
chr15_+_14656797 0.27 ENSDART00000162350
FBXO46
F-box protein 46
chr12_+_20290671 0.26 ENSDART00000115015
arhgap17a
Rho GTPase activating protein 17a
chr5_+_58564645 0.26 ENSDART00000045518
prkrip1
PRKR interacting protein 1 (IL11 inducible)
chr12_+_22459371 0.26 ENSDART00000171725
capgb
capping protein (actin filament), gelsolin-like b
chr19_+_21209328 0.25 ENSDART00000142463
txnl4a
thioredoxin-like 4A
chr17_+_16038103 0.25 ENSDART00000155005
si:ch73-204p21.2
si:ch73-204p21.2
chr5_+_21563703 0.25 ENSDART00000045574
shisa2a
shisa family member 2a
chr23_+_29017954 0.24 ENSDART00000140291
CR677513.1
ENSDARG00000093890
chr6_-_40715613 0.23 ENSDART00000153702
si:ch211-157b11.12
si:ch211-157b11.12
chr16_+_4350448 0.22

chr23_+_22763789 0.22

chr23_+_17912784 0.22 ENSDART00000104647
prim1
primase, DNA, polypeptide 1
chr24_-_14446522 0.22

KN150030v1_-_22572 0.22 ENSDART00000175410
CABZ01079802.1
ENSDARG00000106760
chr21_-_11562321 0.21 ENSDART00000144370
cast
calpastatin
chr12_+_20290592 0.20 ENSDART00000115015
arhgap17a
Rho GTPase activating protein 17a
chr12_+_22459218 0.20 ENSDART00000171725
capgb
capping protein (actin filament), gelsolin-like b
chr16_-_13723295 0.20 ENSDART00000139102
dbpb
D site albumin promoter binding protein b
chr5_+_58564789 0.19 ENSDART00000045518
prkrip1
PRKR interacting protein 1 (IL11 inducible)
chr10_-_2944221 0.19 ENSDART00000132526
marveld2a
MARVEL domain containing 2a
chr23_+_17912834 0.19 ENSDART00000104647
prim1
primase, DNA, polypeptide 1
chr4_+_14728603 0.18 ENSDART00000131666
cmasa
cytidine monophosphate N-acetylneuraminic acid synthetase a
chr16_-_13723352 0.18 ENSDART00000139102
dbpb
D site albumin promoter binding protein b
chr8_-_21110183 0.18 ENSDART00000143192
cpt2
carnitine palmitoyltransferase 2
chr24_-_14447825 0.17

KN149710v1_+_38638 0.17

KN150030v1_-_22642 0.17 ENSDART00000175410
CABZ01079802.1
ENSDARG00000106760
chr18_+_41242278 0.17 ENSDART00000138552
ENSDART00000145863
trip12
thyroid hormone receptor interactor 12
chr12_+_20290791 0.16 ENSDART00000115015
arhgap17a
Rho GTPase activating protein 17a
chr19_+_46567459 0.15 ENSDART00000164055
cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr15_-_5912105 0.15

chr17_-_8413036 0.15 ENSDART00000154713
fzd3b
frizzled class receptor 3b
chr10_+_6925975 0.14

chr5_-_56294194 0.14 ENSDART00000074400
tia1
TIA1 cytotoxic granule-associated RNA binding protein
chr11_-_42148337 0.13 ENSDART00000160704
slmapa
sarcolemma associated protein a
chr2_+_10209233 0.13 ENSDART00000160304
slc35a3b
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr19_+_32000438 0.13 ENSDART00000150910
gmnn
geminin, DNA replication inhibitor
chr16_-_13723778 0.12 ENSDART00000139102
dbpb
D site albumin promoter binding protein b
chr16_-_4350251 0.12

chr8_-_1833095 0.12 ENSDART00000114476
ENSDART00000091235
ENSDART00000140077
pi4kab
phosphatidylinositol 4-kinase, catalytic, alpha b
chr8_-_21110428 0.11 ENSDART00000135938
cpt2
carnitine palmitoyltransferase 2
chr5_+_26925392 0.11 ENSDART00000051491
sfrp1a
secreted frizzled-related protein 1a
chr7_+_72925910 0.11 ENSDART00000175267
ENSDART00000179638
CABZ01067170.1
ENSDARG00000106453
chr24_-_16878970 0.11 ENSDART00000106058
ENSDART00000106057
ptgdsb.2
prostaglandin D2 synthase b, tandem duplicate 2
chr16_+_27837465 0.10

chr11_-_6442836 0.09 ENSDART00000004483
zgc:162969
zgc:162969
chr24_-_14447136 0.09

chr4_+_13587809 0.09 ENSDART00000138201
tnpo3
transportin 3
chr19_-_8849482 0.09 ENSDART00000170416
si:ch73-350k19.1
si:ch73-350k19.1
chr16_-_29259838 0.09 ENSDART00000178967
mef2d
myocyte enhancer factor 2d
chr20_-_16366248 0.08

chr14_-_6901783 0.08 ENSDART00000167994
ENSDART00000166532
stox2b
storkhead box 2b
chr15_+_14656886 0.08 ENSDART00000162350
FBXO46
F-box protein 46
chr4_+_11465367 0.08 ENSDART00000008584
gdi2
GDP dissociation inhibitor 2
chr8_+_18552850 0.08 ENSDART00000177476
prrg1
proline rich Gla (G-carboxyglutamic acid) 1
chr22_-_36816215 0.08

chr1_-_57301027 0.07 ENSDART00000081122
COLGALT1 (1 of many)
collagen beta(1-O)galactosyltransferase 1
chr8_-_21110262 0.07 ENSDART00000143192
cpt2
carnitine palmitoyltransferase 2
chr3_-_26052785 0.07 ENSDART00000147517
si:ch211-11k18.4
si:ch211-11k18.4
chr24_-_14447655 0.07

chr6_-_40715579 0.07 ENSDART00000157113
ENSDART00000154810
si:ch211-157b11.12
si:ch211-157b11.12
chr21_-_11561793 0.07 ENSDART00000171708
ENSDART00000081614
cast
calpastatin
chr19_+_21783204 0.07 ENSDART00000024639
tshz1
teashirt zinc finger homeobox 1
chr25_-_3345176 0.07 ENSDART00000029067
hbp1
HMG-box transcription factor 1
chr20_+_28901045 0.06 ENSDART00000153046
fntb
farnesyltransferase, CAAX box, beta
chr3_-_16569378 0.06 ENSDART00000055859
pold1
polymerase (DNA directed), delta 1, catalytic subunit
chr16_+_4350419 0.06

chr11_-_44539726 0.06 ENSDART00000173360
map1lc3c
microtubule-associated protein 1 light chain 3 gamma
chr20_-_22170411 0.06 ENSDART00000155568
BX088688.3
ENSDARG00000097598
chr14_-_4117151 0.06

chr2_+_40424102 0.05 ENSDART00000170089
epha4b
eph receptor A4b
chr24_-_16884946 0.05 ENSDART00000171988
ptgdsb.2
prostaglandin D2 synthase b, tandem duplicate 2
chr7_-_64172974 0.05 ENSDART00000172619
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr18_+_41242323 0.05 ENSDART00000138552
ENSDART00000145863
trip12
thyroid hormone receptor interactor 12
chr7_+_16696469 0.04

chr11_+_38013238 0.04 ENSDART00000171496
CDK18
cyclin dependent kinase 18
chr2_-_15656155 0.04 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr1_-_10373506 0.04

chr9_-_45096523 0.03 ENSDART00000110697
dnajc10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr23_+_22763861 0.02

chr15_-_5911817 0.02

chr17_+_24803152 0.02 ENSDART00000112313
wdr43
WD repeat domain 43
chr1_+_9633924 0.02 ENSDART00000029774
tmem55bb
transmembrane protein 55Bb
chr16_+_42567668 0.01 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr10_-_34927807 0.01 ENSDART00000138755
dclk1a
doublecortin-like kinase 1a
chr7_+_28896401 0.01 ENSDART00000076345
slc38a8b
solute carrier family 38, member 8b
chr7_-_64173039 0.01 ENSDART00000172619
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr11_-_44539778 0.01 ENSDART00000161846
map1lc3c
microtubule-associated protein 1 light chain 3 gamma
chr2_-_28687065 0.01 ENSDART00000164657
dhcr7
7-dehydrocholesterol reductase
chr5_-_31726751 0.01

chr7_+_65532871 0.00 ENSDART00000082740
CT573494.2
ENSDARG00000097673
chr13_-_36164510 0.00 ENSDART00000169768
slc8a3
solute carrier family 8 (sodium/calcium exchanger), member 3
chr6_-_16156294 0.00 ENSDART00000160809
agap1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.4 GO:0060965 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.1 0.7 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.6 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 1.4 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.2 GO:0045761 regulation of cAMP metabolic process(GO:0030814) regulation of cAMP biosynthetic process(GO:0030817) regulation of adenylate cyclase activity(GO:0045761)
0.0 0.5 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.6 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.4 GO:0051014 actin filament severing(GO:0051014)
0.0 0.6 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.1 GO:0033182 regulation of histone ubiquitination(GO:0033182) negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.1 GO:0097354 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.4 GO:0006635 fatty acid beta-oxidation(GO:0006635)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.4 GO:1990077 primosome complex(GO:1990077)
0.0 0.5 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.3 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0050699 WW domain binding(GO:0050699)
0.1 0.4 GO:0003896 DNA primase activity(GO:0003896)
0.1 0.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.7 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.4 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.5 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.1 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway