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Results for dlx4a+dlx4b_dlx2a+dlx2b

Z-value: 0.77

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Transcription factors associated with dlx4a+dlx4b_dlx2a+dlx2b

Gene Symbol Gene ID Gene Info
dlx4a
ENSDARG00000011956 distal-less homeobox 4a
dlx4b
ENSDARG00000071560 distal-less homeobox 4b
dlx2b
ENSDARG00000017174 distal-less homeobox 2b
dlx2a
ENSDARG00000079964 distal-less homeobox 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
dlx4adr10_dc_chr3_+_34540552_345406090.862.3e-05Click!
dlx2adr10_dc_chr9_-_3429153_34291990.692.8e-03Click!
dlx4bdr10_dc_chr12_-_5693715_56937600.693.2e-03Click!

Activity profile of dlx4a+dlx4b_dlx2a+dlx2b motif

Sorted Z-values of dlx4a+dlx4b_dlx2a+dlx2b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of dlx4a+dlx4b_dlx2a+dlx2b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr12_+_24221087 3.74 ENSDART00000088178
nrxn1a
neurexin 1a
chr2_-_23348612 2.50 ENSDART00000110373
znf414
zinc finger protein 414
chr8_+_21321765 2.47 ENSDART00000131691
alas2
aminolevulinate, delta-, synthase 2
chr21_+_28441951 2.35 ENSDART00000077887
slc22a6l
solute carrier family 22 (organic anion transporter), member 6, like
chr20_-_22576513 2.00 ENSDART00000103510
pdgfra
platelet-derived growth factor receptor, alpha polypeptide
chr3_-_35928594 1.99

chr20_-_29517770 1.93 ENSDART00000147464
ryr3
ryanodine receptor 3
chr7_+_30516734 1.71 ENSDART00000174000
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr2_+_49358871 1.70 ENSDART00000179089
sema6ba
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba
chr16_+_46145286 1.52 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr17_-_31642673 1.50 ENSDART00000030448
vsx2
visual system homeobox 2
chr14_+_20045365 1.46 ENSDART00000167637
aff2
AF4/FMR2 family, member 2
chr20_-_40823307 1.46 ENSDART00000061261
cx43
connexin 43
chr16_-_17439735 1.45 ENSDART00000144392
zyx
zyxin
chr9_-_41608298 1.38

chr2_-_36058327 1.38 ENSDART00000003550
nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr16_-_13733759 1.37 ENSDART00000164344
si:dkeyp-69b9.6
si:dkeyp-69b9.6
chr18_-_43890514 1.37 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr3_+_17210396 1.35 ENSDART00000090676
si:ch211-210g13.5
si:ch211-210g13.5
chr23_-_12310778 1.33 ENSDART00000131256
phactr3a
phosphatase and actin regulator 3a
chr13_+_27654900 1.28 ENSDART00000160550
CR356236.1
ENSDARG00000102040
chr16_+_23172295 1.27 ENSDART00000167518
ENSDART00000161087
efna3b
ephrin-A3b
chr8_-_15091823 1.26 ENSDART00000142358
bcar3
breast cancer anti-estrogen resistance 3
chr15_-_20088439 1.25 ENSDART00000161379
auts2b
autism susceptibility candidate 2b
chr16_+_29060022 1.24 ENSDART00000088023
gon4l
gon-4-like (C. elegans)
chr7_-_27877036 1.22 ENSDART00000044208
lmo1
LIM domain only 1
chr15_-_1858350 1.21 ENSDART00000082026
mmp28
matrix metallopeptidase 28
chr2_+_29992879 1.19 ENSDART00000056748
en2b
engrailed homeobox 2b
chr13_-_31304614 1.18

chr7_-_25623974 1.18 ENSDART00000173602
cd99l2
CD99 molecule-like 2
chr22_+_16509286 1.17 ENSDART00000083063
tal1
T-cell acute lymphocytic leukemia 1
chr1_-_25600988 1.16 ENSDART00000160381
cxxc4
CXXC finger 4
chr11_-_6442836 1.13 ENSDART00000004483
zgc:162969
zgc:162969
chr19_-_43037791 1.13 ENSDART00000004392
fkbp9
FK506 binding protein 9
chr23_+_28804842 1.10 ENSDART00000047378
sst3
somatostatin 3
chr16_+_21104310 1.09 ENSDART00000046766
hoxa10b
homeobox A10b
chr8_-_23591082 1.06 ENSDART00000025024
slc38a5b
solute carrier family 38, member 5b
chr2_-_17564676 1.04 ENSDART00000144251
artnb
artemin b
chr9_+_36316158 1.01 ENSDART00000176763
lrp1bb
low density lipoprotein receptor-related protein 1Bb
chr7_+_54410044 1.00

chr24_+_40292617 1.00

chr17_+_23278879 0.97 ENSDART00000153652
zgc:165461
zgc:165461
chr1_-_50215233 0.96 ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr13_-_44492897 0.96

chr16_+_51319421 0.93

chr25_+_34069931 0.93

chr4_+_11385828 0.91

chr24_+_30343687 0.91 ENSDART00000162377
FP085414.1
ENSDARG00000100270
chr4_+_12616987 0.91 ENSDART00000003583
lmo3
LIM domain only 3
chr20_-_9474672 0.88 ENSDART00000152674
ENSDARG00000033201
ENSDARG00000033201
chr20_-_23526954 0.88 ENSDART00000004625
zar1
zygote arrest 1
chr21_-_17259886 0.87 ENSDART00000114877
gfi1b
growth factor independent 1B transcription repressor
chr1_+_38834751 0.85 ENSDART00000137676
tenm3
teneurin transmembrane protein 3
chr2_+_36718808 0.85 ENSDART00000002510
golim4b
golgi integral membrane protein 4b
chr13_-_49695322 0.83

chr12_+_20230575 0.81 ENSDART00000066383
hbae5
hemoglobin, alpha embryonic 5
chr20_-_5184885 0.81 ENSDART00000114851
ccdc85cb
coiled-coil domain containing 85C, b
chr16_+_13928844 0.81 ENSDART00000090191
flcn
folliculin
chr5_+_38237115 0.80 ENSDART00000160236
fras1
Fraser extracellular matrix complex subunit 1
chr4_+_12617165 0.80 ENSDART00000003583
lmo3
LIM domain only 3
chr21_-_9863186 0.80 ENSDART00000170710
arhgap24
Rho GTPase activating protein 24
chr21_+_26684617 0.77 ENSDART00000053797
slc3a2b
solute carrier family 3 (amino acid transporter heavy chain), member 2b
chr17_-_47893203 0.77

chr13_+_25319230 0.75 ENSDART00000101328
atoh7
atonal bHLH transcription factor 7
chr19_+_22478256 0.74 ENSDART00000100181
sall3b
spalt-like transcription factor 3b
chr4_+_16896821 0.72 ENSDART00000017726
etnk1
ethanolamine kinase 1
chr20_-_35343057 0.72 ENSDART00000113294
fzd3a
frizzled class receptor 3a
chr4_-_15442828 0.71 ENSDART00000157414
plxna4
plexin A4
chr17_-_29102320 0.71 ENSDART00000104204
foxg1a
forkhead box G1a
chr18_+_48426375 0.69

chr7_+_42124857 0.68 ENSDART00000004120
adamts18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr9_-_20562293 0.68 ENSDART00000113418
igsf3
immunoglobulin superfamily, member 3
chr5_+_3965645 0.67 ENSDART00000100061
prdx4
peroxiredoxin 4
chr6_-_14162846 0.67 ENSDART00000100762
inpp4ab
inositol polyphosphate-4-phosphatase type I Ab
chr17_+_24668907 0.66 ENSDART00000034263
ENSDART00000135794
sepn1
selenoprotein N, 1
chr15_-_40391882 0.66

chr6_+_23787804 0.65 ENSDART00000163188
znf648
zinc finger protein 648
chr15_-_23441268 0.63 ENSDART00000078570
c1qtnf5
C1q and TNF related 5
chr16_+_17481157 0.62 ENSDART00000173448
fam131bb
family with sequence similarity 131, member Bb
chr6_-_54816183 0.62 ENSDART00000148462
tnni1b
troponin I type 1b (skeletal, slow)
chr24_+_30343717 0.62 ENSDART00000162377
FP085414.1
ENSDARG00000100270
chr17_-_44133941 0.62 ENSDART00000126097
otx2
orthodenticle homeobox 2
chr16_+_13928376 0.61 ENSDART00000163251
flcn
folliculin
chr1_-_4757890 0.60 ENSDART00000114035
mnx2b
motor neuron and pancreas homeobox 2b
chr8_+_28240085 0.60 ENSDART00000110857
fam212b
family with sequence similarity 212, member B
chr20_-_20502615 0.60

chr23_-_7740845 0.59 ENSDART00000172451
plagl2
pleiomorphic adenoma gene-like 2
chr4_+_12613575 0.59 ENSDART00000133767
lmo3
LIM domain only 3
chr6_-_6330710 0.59 ENSDART00000137642
cep170ab
centrosomal protein 170Ab
chr6_-_8075384 0.58 ENSDART00000129674
slc44a2
solute carrier family 44 (choline transporter), member 2
chr21_+_28921734 0.58 ENSDART00000166575
ppp3ca
protein phosphatase 3, catalytic subunit, alpha isozyme
chr6_+_8895437 0.57 ENSDART00000162588
rgn
regucalcin
chr23_-_28286971 0.57

chr7_-_52848084 0.56 ENSDART00000172179
ENSDART00000167882
cdh1
cadherin 1, type 1, E-cadherin (epithelial)
chr20_-_46458839 0.54 ENSDART00000153087
bmf2
Bcl2 modifying factor 2
chr22_+_16282153 0.54 ENSDART00000162685
ENSDART00000105678
lrrc39
leucine rich repeat containing 39
chr3_+_47412661 0.53 ENSDART00000155648
ube2ia
ubiquitin-conjugating enzyme E2Ia
chr21_+_27379622 0.53 ENSDART00000108763
cfb
complement factor B
chr8_-_46903869 0.53 ENSDART00000161462
acot7
acyl-CoA thioesterase 7
chr11_+_37639045 0.53 ENSDART00000111157
si:ch211-112f3.4
si:ch211-112f3.4
chr19_-_25842461 0.52

chr10_-_35293024 0.52 ENSDART00000145804
ypel2a
yippee-like 2a
chr21_-_11561855 0.51 ENSDART00000162426
cast
calpastatin
chr17_-_21179064 0.47

chr23_+_34037058 0.46 ENSDART00000140666
prosc
pyridoxal phosphate binding protein
chr4_-_22751641 0.45 ENSDART00000066903
ENSDART00000130072
ENSDART00000123369
kmt2e
lysine (K)-specific methyltransferase 2E
chr19_-_7439294 0.45

chr20_+_28958586 0.44 ENSDART00000142678
slc10a1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr15_+_4079643 0.44

chr20_-_23527004 0.44 ENSDART00000004625
zar1
zygote arrest 1
chr8_+_20592099 0.43 ENSDART00000160421
nfic
nuclear factor I/C
chr22_-_7371498 0.43

KN149726v1_+_1094 0.42

chr18_-_7184699 0.40 ENSDART00000135587
cd9a
CD9 molecule a
chr12_-_29190576 0.40 ENSDART00000153458
sh2d4bb
SH2 domain containing 4Bb
chr24_-_11103952 0.39

chr8_-_38444845 0.38 ENSDART00000075989
inpp5l
inositol polyphosphate-5-phosphatase L
chr19_+_21783429 0.38 ENSDART00000024639
tshz1
teashirt zinc finger homeobox 1
chr15_-_25582891 0.38

chr2_-_7375138 0.37 ENSDART00000146434
zgc:153115
zgc:153115
chr22_-_20141589 0.37 ENSDART00000085913
btbd2a
BTB (POZ) domain containing 2a
chr20_-_48255596 0.37 ENSDART00000031167
tfap2d
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr13_+_24619864 0.37 ENSDART00000021053
col17a1b
collagen, type XVII, alpha 1b
chr3_+_39514598 0.36 ENSDART00000156038
epn2
epsin 2
chr24_+_9272045 0.36 ENSDART00000132724
si:ch211-285f17.1
si:ch211-285f17.1
chr8_+_44719191 0.36 ENSDART00000163381
elmod3
ELMO/CED-12 domain containing 3
chr7_-_25624212 0.35 ENSDART00000173505
cd99l2
CD99 molecule-like 2
chr2_+_33343287 0.35 ENSDART00000056655
klf17
Kruppel-like factor 17
chr5_-_67233396 0.34 ENSDART00000051833
ENSDART00000124890
gsx1
GS homeobox 1
chr13_+_25590508 0.34 ENSDART00000046050
pcbd1
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
chr22_-_11106940 0.34 ENSDART00000016873
atp6ap2
ATPase, H+ transporting, lysosomal accessory protein 2
chr3_-_32205873 0.33 ENSDART00000156918
si:dkey-16p21.8
si:dkey-16p21.8
chr12_-_26062065 0.33 ENSDART00000076051
opn4b
opsin 4b
chr13_-_36785295 0.32 ENSDART00000167154
trim9
tripartite motif containing 9
chr17_-_23426752 0.32 ENSDART00000104715
pcgf5a
polycomb group ring finger 5a
chr10_+_3461461 0.31

chr11_-_18068313 0.30

chr20_-_10133201 0.30 ENSDART00000144970
meis2b
Meis homeobox 2b
chr17_-_21180028 0.30 ENSDART00000104708
abhd12
abhydrolase domain containing 12
chr11_-_37730181 0.29 ENSDART00000102870
slc41a1
solute carrier family 41 (magnesium transporter), member 1
chr16_-_20084451 0.29 ENSDART00000079155
hdac9b
histone deacetylase 9b
chr21_-_21477423 0.29 ENSDART00000164076
pvrl3b
poliovirus receptor-related 3b
chr23_+_36016450 0.29 ENSDART00000103035
hoxc6a
homeobox C6a
chr6_+_3120600 0.28 ENSDART00000151359
kdm4aa
lysine (K)-specific demethylase 4A, genome duplicate a
chr16_+_22702982 0.28 ENSDART00000041625
chrnb2b
cholinergic receptor, nicotinic, beta 2b
chr19_+_21783111 0.27 ENSDART00000024639
tshz1
teashirt zinc finger homeobox 1
chr1_+_11290598 0.27 ENSDART00000103399
tspan5b
tetraspanin 5b
chr7_-_25624128 0.26 ENSDART00000173505
cd99l2
CD99 molecule-like 2
chr14_+_15698814 0.25

chr22_-_20141216 0.25 ENSDART00000128023
btbd2a
BTB (POZ) domain containing 2a
chr8_-_19166630 0.25

chr1_-_40536800 0.24 ENSDART00000134739
rgs12b
regulator of G protein signaling 12b
chr20_-_37587804 0.24 ENSDART00000166106
si:ch211-202p1.5
si:ch211-202p1.5
chr5_+_36431824 0.22 ENSDART00000045036
nfkbib
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr16_+_35708856 0.22 ENSDART00000161393
map7d1a
MAP7 domain containing 1a
chr10_-_41478085 0.22 ENSDART00000009838
gpat4
glycerol-3-phosphate acyltransferase 4
chr3_+_14151127 0.21 ENSDART00000162023
plppr2a
phospholipid phosphatase related 2a
chr19_-_42759951 0.21

chr3_-_16569378 0.20 ENSDART00000055859
pold1
polymerase (DNA directed), delta 1, catalytic subunit
chr5_+_26217533 0.19

chr11_+_38013238 0.18 ENSDART00000171496
CDK18
cyclin dependent kinase 18
chr19_-_20203902 0.18 ENSDART00000172668
CR382300.3
ENSDARG00000101330
chr11_-_22143133 0.17 ENSDART00000159681
tfeb
transcription factor EB
chr12_+_22137783 0.17 ENSDART00000131175
wnt3
wingless-type MMTV integration site family, member 3
chr15_-_16241341 0.16 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr24_+_33697332 0.16

chr17_-_44133970 0.16 ENSDART00000126097
otx2
orthodenticle homeobox 2
chr5_+_19153421 0.15

chr21_-_11561978 0.14 ENSDART00000132699
cast
calpastatin
chr2_+_50873893 0.13

chr17_-_29102271 0.13 ENSDART00000104204
foxg1a
forkhead box G1a
chr1_-_10373506 0.13

chr3_-_8608620 0.13

chr6_+_50393779 0.13 ENSDART00000055502
ergic3
ERGIC and golgi 3
chr8_+_25015374 0.12 ENSDART00000140617
ngrn
neugrin, neurite outgrowth associated
chr22_-_23518719 0.12 ENSDART00000161253
crb1
crumbs family member 1, photoreceptor morphogenesis associated
chr4_-_13189038 0.12 ENSDART00000162277
grip1
glutamate receptor interacting protein 1
chr23_-_294139 0.12 ENSDART00000143125
anks1aa
ankyrin repeat and sterile alpha motif domain containing 1Aa
chr19_-_42759922 0.11

chr8_+_25015325 0.11 ENSDART00000140617
ngrn
neugrin, neurite outgrowth associated
chr21_+_29040831 0.11 ENSDART00000166403
ecscr
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr10_-_34927807 0.11 ENSDART00000138755
dclk1a
doublecortin-like kinase 1a
chr21_+_26684728 0.10 ENSDART00000053797
slc3a2b
solute carrier family 3 (amino acid transporter heavy chain), member 2b
chr25_+_6607551 0.10 ENSDART00000176596
FQ377991.1
ENSDARG00000108452
chr9_-_21649243 0.09 ENSDART00000133469
zmym2
zinc finger, MYM-type 2
chr6_-_23454902 0.09 ENSDART00000157527
ENSDART00000168882
ENSDART00000171384
ntn1a
netrin 1a
chr3_+_14151244 0.09 ENSDART00000162023
plppr2a
phospholipid phosphatase related 2a
chr6_+_40924749 0.07 ENSDART00000133599
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr2_+_38165187 0.07 ENSDART00000135307
sall2
spalt-like transcription factor 2
chr6_-_23455008 0.06 ENSDART00000157527
ENSDART00000168882
ENSDART00000171384
ntn1a
netrin 1a
chr24_-_39630728 0.05 ENSDART00000031486
lyrm1
LYR motif containing 1
chr12_-_34636654 0.04

chr3_+_33309011 0.04 ENSDART00000164322
gtpbp1
GTP binding protein 1
chr19_+_20213125 0.04 ENSDART00000167757
hoxa1a
homeobox A1a
chr21_+_40393503 0.03 ENSDART00000171244
ssh2b
slingshot protein phosphatase 2b
chr3_+_27655753 0.03 ENSDART00000086994
nat15
N-acetyltransferase 15 (GCN5-related, putative)
chr1_-_54087595 0.03 ENSDART00000150362
si:ch211-197k17.3
si:ch211-197k17.3
chr2_+_31850752 0.02 ENSDART00000066788
epdr1
ependymin related 1
chr4_+_12613877 0.02 ENSDART00000133767
lmo3
LIM domain only 3
chr24_-_14447136 0.01

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.3 0.9 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.2 2.0 GO:0003315 heart rudiment formation(GO:0003315)
0.2 1.0 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.2 2.5 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.2 0.8 GO:1900028 negative regulation of Rac protein signal transduction(GO:0035021) wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.1 0.6 GO:0019852 L-ascorbic acid metabolic process(GO:0019852) water-soluble vitamin biosynthetic process(GO:0042364) regulation of calcium-mediated signaling(GO:0050848)
0.1 1.4 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846) positive regulation of TORC1 signaling(GO:1904263)
0.1 1.4 GO:0009435 NAD biosynthetic process(GO:0009435)
0.1 0.6 GO:0003379 establishment of cell polarity involved in gastrulation cell migration(GO:0003379)
0.1 0.9 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
0.1 1.5 GO:0061074 regulation of neural retina development(GO:0061074)
0.1 0.7 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 1.2 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 1.5 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.3 GO:0048785 hatching gland development(GO:0048785)
0.1 0.2 GO:0050886 phasic smooth muscle contraction(GO:0014821) endocrine process(GO:0050886)
0.1 1.0 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.1 0.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.2 GO:1902024 serine transport(GO:0032329) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 0.7 GO:0021754 facial nucleus development(GO:0021754)
0.1 1.9 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.1 0.8 GO:0043584 nose development(GO:0043584)
0.1 1.4 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.6 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.5 GO:0006956 complement activation(GO:0006956)
0.1 0.5 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.3 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.5 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.8 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.2 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 1.0 GO:0036269 swimming behavior(GO:0036269)
0.0 0.1 GO:0061626 ventral aorta development(GO:0035908) pharyngeal arch artery morphogenesis(GO:0061626)
0.0 0.3 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 1.7 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 3.7 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.6 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.5 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.5 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 0.3 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.0 1.5 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.5 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.2 GO:0030901 midbrain development(GO:0030901)
0.0 0.3 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.6 GO:0015696 ammonium transport(GO:0015696)
0.0 0.1 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 1.5 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.3 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.2 GO:0006959 humoral immune response(GO:0006959)
0.0 1.3 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.1 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.9 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.3 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.3 GO:0098916 chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 1.5 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.8 GO:0005833 hemoglobin complex(GO:0005833) haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.6 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.5 GO:0031430 M band(GO:0031430)
0.0 0.4 GO:0030669 clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 1.7 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 1.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.5 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.6 GO:0005861 troponin complex(GO:0005861)
0.0 3.1 GO:0005929 cilium(GO:0005929)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0005902 microvillus(GO:0005902)
0.0 0.5 GO:0016459 myosin complex(GO:0016459)
0.0 1.5 GO:0030424 axon(GO:0030424)
0.0 0.8 GO:0005925 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.3 1.5 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.2 0.7 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.2 0.7 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.5 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.6 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.1 0.8 GO:0031720 haptoglobin binding(GO:0031720)
0.1 1.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.6 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.4 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 2.5 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.1 1.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 0.4 GO:0052659 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.1 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.5 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 3.0 GO:0019838 growth factor binding(GO:0019838)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 1.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.3 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 1.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 2.3 GO:0008514 organic anion transmembrane transporter activity(GO:0008514)
0.0 2.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.2 GO:0071855 neuropeptide receptor binding(GO:0071855)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 0.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.9 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.2 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 0.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 0.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME BILE ACID AND BILE SALT METABOLISM Genes involved in Bile acid and bile salt metabolism
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.9 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 1.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants