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Results for ebf1b

Z-value: 0.84

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Transcription factors associated with ebf1b

Gene Symbol Gene ID Gene Info
ebf1b
ENSDARG00000069196 EBF transcription factor 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ebf1bdr10_dc_chr21_-_33961137_339611590.844.5e-05Click!

Activity profile of ebf1b motif

Sorted Z-values of ebf1b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ebf1b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr24_-_28814066 3.91 ENSDART00000042065
ENSDART00000170675
ENSDART00000158668
col11a1a
collagen, type XI, alpha 1a
chr11_+_6118409 2.91 ENSDART00000027666
nr2f6b
nuclear receptor subfamily 2, group F, member 6b
chr7_-_32752138 2.54 ENSDART00000052383
cd81a
CD81 molecule a
chr22_+_11726312 2.42 ENSDART00000155366
krt96
keratin 96
chr2_-_30675594 2.33 ENSDART00000087270
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr13_-_39033893 2.12 ENSDART00000045434
col9a1b
collagen, type IX, alpha 1b
chr19_+_20183210 2.11 ENSDART00000164968
hoxa4a
homeobox A4a
chr21_+_26352675 2.05 ENSDART00000077197
tmsb
thymosin, beta
chr9_+_41720118 1.88

chr18_+_38773971 1.84 ENSDART00000010177
onecut1
one cut homeobox 1
chr10_-_31619761 1.83 ENSDART00000023575
robo3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr7_-_52283383 1.77 ENSDART00000165649
tcf12
transcription factor 12
chr25_+_11317025 1.73

chr25_+_30746445 1.66 ENSDART00000156916
lsp1
lymphocyte-specific protein 1
chr2_+_19546837 1.62 ENSDART00000163137
elovl1a
ELOVL fatty acid elongase 1a
chr7_+_25649559 1.61 ENSDART00000026295
arrb2b
arrestin, beta 2b
chr25_+_25358457 1.56 ENSDART00000112330
rassf7a
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7a
chr2_+_57136624 1.52 ENSDART00000159912
ENSDARG00000105208
ENSDARG00000105208
chr4_-_10600228 1.42 ENSDART00000048003
tspan12
tetraspanin 12
chr20_+_30948175 1.41

chr2_+_22839514 1.33 ENSDART00000167915
lrrc8da
leucine rich repeat containing 8 family, member Da
chr8_-_15144533 1.32 ENSDART00000138855
bcar3
breast cancer anti-estrogen resistance 3
chr11_+_6118322 1.32 ENSDART00000165031
nr2f6b
nuclear receptor subfamily 2, group F, member 6b
chr13_+_1308683 1.13 ENSDART00000159047
si:ch211-165e15.1
si:ch211-165e15.1
chr12_+_13614102 1.10 ENSDART00000152689
oplah
5-oxoprolinase (ATP-hydrolysing)
chr16_-_30606364 1.05 ENSDART00000147986
lmna
lamin A
chr23_+_23305483 1.04 ENSDART00000126479
plekhn1
pleckstrin homology domain containing, family N member 1
chr7_-_33994315 1.02 ENSDART00000173596
si:ch211-98n17.5
si:ch211-98n17.5
chr8_+_39525254 1.00

chr4_+_13811932 0.99 ENSDART00000067168
pdzrn4
PDZ domain containing ring finger 4
chr14_-_21662462 0.98 ENSDART00000021417
p2rx3a
purinergic receptor P2X, ligand-gated ion channel, 3a
chr10_+_26156392 0.95 ENSDART00000079207
trim47
tripartite motif containing 47
chr23_-_45266310 0.94

chr8_-_24276524 0.93

chr24_-_28813986 0.89 ENSDART00000042065
ENSDART00000170675
ENSDART00000158668
col11a1a
collagen, type XI, alpha 1a
chr8_-_38308535 0.88

chr11_-_9479592 0.83 ENSDART00000175829
CU179643.1
ENSDARG00000086489
chr5_-_57016269 0.83 ENSDART00000074264
crfb12
cytokine receptor family member B12
chr10_+_21693418 0.82 ENSDART00000160754
pcdh1g1
protocadherin 1 gamma 1
chr3_-_30027552 0.79 ENSDART00000103502
si:ch211-152f23.5
si:ch211-152f23.5
chr3_-_38642067 0.79 ENSDART00000155518
znf281a
zinc finger protein 281a
chr11_-_39864306 0.79 ENSDART00000165781
fam83e
family with sequence similarity 83, member E
chr5_-_63912916 0.79

chr16_-_21981065 0.76 ENSDART00000078858
si:ch73-86n18.1
si:ch73-86n18.1
chr24_-_25546068 0.76 ENSDART00000015391
chrnd
cholinergic receptor, nicotinic, delta (muscle)
chr7_-_57727148 0.73

chr15_+_42626315 0.72

chr3_+_52901602 0.71 ENSDART00000114343
brd4
bromodomain containing 4
chr7_+_58384379 0.70 ENSDART00000052332
penkb
proenkephalin b
chr21_-_18981828 0.70 ENSDART00000080256
nefma
neurofilament, medium polypeptide a
chr13_+_28574593 0.69 ENSDART00000126845
ldb1a
LIM domain binding 1a
chr11_-_30792331 0.68

chr20_+_30979286 0.68

chr13_+_28723589 0.67

chr9_-_5618609 0.66 ENSDART00000127219
FAM155A
family with sequence similarity 155 member A
chr6_+_42478185 0.66 ENSDART00000150226
mst1ra
macrophage stimulating 1 receptor a
chr24_-_25545773 0.65 ENSDART00000015391
chrnd
cholinergic receptor, nicotinic, delta (muscle)
chr22_+_11726429 0.61 ENSDART00000155366
krt96
keratin 96
chr11_-_9479689 0.61 ENSDART00000175829
CU179643.1
ENSDARG00000086489
chr19_-_27363603 0.61

chr2_-_39709905 0.60 ENSDART00000147821
spsb4a
splA/ryanodine receptor domain and SOCS box containing 4a
chr11_-_39864543 0.56 ENSDART00000165781
fam83e
family with sequence similarity 83, member E
chr1_+_44044807 0.56 ENSDART00000133926
ENSDART00000049701
p2rx3b
purinergic receptor P2X, ligand-gated ion channel, 3b
chr11_-_22143133 0.55 ENSDART00000159681
tfeb
transcription factor EB
chr23_+_18565721 0.54

chr25_-_34621069 0.47 ENSDART00000123892
hist1h4l
histone 1, H4, like
chr24_-_12602773 0.47 ENSDART00000093583
cox19
COX19 cytochrome c oxidase assembly factor
chr4_+_20596509 0.46

chr5_-_63912962 0.45

chr13_-_39033849 0.44 ENSDART00000045434
col9a1b
collagen, type IX, alpha 1b
chr12_+_5283561 0.43

chr6_+_48490235 0.43 ENSDART00000161184
si:dkey-238f9.1
si:dkey-238f9.1
chr16_+_24047857 0.42

chr4_-_10600179 0.42 ENSDART00000048003
tspan12
tetraspanin 12
chr24_-_28813917 0.42 ENSDART00000042065
ENSDART00000170675
ENSDART00000158668
col11a1a
collagen, type XI, alpha 1a
chr6_+_55091896 0.42

chr20_+_48950833 0.41 ENSDART00000159275
nkx2.2b
NK2 homeobox 2b
chr10_+_45213089 0.41 ENSDART00000166945
nudcd3
NudC domain containing 3
KN150708v1_-_31573 0.41 ENSDART00000160040
slc16a6a
solute carrier family 16, member 6a
chr5_+_3965645 0.40 ENSDART00000100061
prdx4
peroxiredoxin 4
chr6_-_25393928 0.40 ENSDART00000160544
PKN2 (1 of many)
protein kinase N2
chr6_+_15018104 0.39 ENSDART00000063648
nck2b
NCK adaptor protein 2b
chr25_+_19568627 0.38 ENSDART00000112746
zgc:171459
zgc:171459
chr7_+_54347388 0.37 ENSDART00000158898
fgf4
fibroblast growth factor 4
chr20_-_23526954 0.37 ENSDART00000004625
zar1
zygote arrest 1
chr16_+_24047649 0.36

chr25_+_30473054 0.36

chr2_+_43757541 0.36

chr1_-_5284684 0.35

chr3_-_41944723 0.35 ENSDART00000083111
ttyh3a
tweety family member 3a
chr7_-_8715924 0.34 ENSDART00000111002
si:ch211-74f19.2
si:ch211-74f19.2
chr1_-_32647357 0.34 ENSDART00000136383
cd99
CD99 molecule
chr3_+_45345181 0.33

chr24_-_26594117 0.33 ENSDART00000124580
pld1b
phospholipase D1b
chr23_+_8261065 0.32 ENSDART00000044733
NPBWR2 (1 of many)
neuropeptides B and W receptor 2
chr20_+_31381039 0.32

chr24_-_28814284 0.31 ENSDART00000003503
col11a1a
collagen, type XI, alpha 1a
chr24_-_26594053 0.30 ENSDART00000124580
pld1b
phospholipase D1b
chr10_-_13438574 0.30 ENSDART00000030976
il11ra
interleukin 11 receptor, alpha
chr7_-_33690318 0.28 ENSDART00000100104
skor1a
SKI family transcriptional corepressor 1a
chr10_+_19597171 0.26 ENSDART00000063810
ENSDART00000063806
atp6v1b2
ATPase, H+ transporting, lysosomal, V1 subunit B2
chr6_+_32428877 0.26

chr18_-_15582896 0.26 ENSDART00000172690
ENSDART00000159915
ppfibp1b
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr6_-_31268267 0.25

chr14_-_6680725 0.24 ENSDART00000060990
eif4ebp3l
eukaryotic translation initiation factor 4E binding protein 3, like
chr4_-_2877346 0.24

chr23_-_45266173 0.23

chr3_-_19847002 0.23

chr19_+_39100820 0.21

chr5_+_36332564 0.20 ENSDART00000037879
crx
cone-rod homeobox
chr15_-_1519571 0.19 ENSDART00000129356
si:dkeyp-97b10.3
si:dkeyp-97b10.3
chr6_+_55091976 0.19

chr15_-_8786861 0.18 ENSDART00000154171
arhgap35a
Rho GTPase activating protein 35a
chr11_-_39864489 0.17 ENSDART00000165781
fam83e
family with sequence similarity 83, member E
chr8_+_31863748 0.16 ENSDART00000146933
c7a
complement component 7a
chr14_-_29498646 0.16

chr16_+_24047736 0.13

chr24_-_17089437 0.13

chr3_-_5318012 0.13 ENSDART00000137105
myh9b
myosin, heavy chain 9b, non-muscle
chr2_-_22173254 0.12 ENSDART00000137538
rab2a
RAB2A, member RAS oncogene family
chr15_-_9655500 0.12 ENSDART00000171214
ENSDART00000171911
nars2
asparaginyl-tRNA synthetase 2, mitochondrial (putative)
chr24_-_40962072 0.06

chr3_+_62051743 0.06 ENSDART00000168063
zgc:173575
zgc:173575
chr7_+_39183037 0.05 ENSDART00000173520
tnnt3b
troponin T type 3b (skeletal, fast)
chr11_+_31295037 0.04 ENSDART00000140204
egln1b
egl-9 family hypoxia-inducible factor 1b
chr18_+_18598885 0.02

chr12_-_33258663 0.00 ENSDART00000001907
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0019730 antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.5 1.6 GO:0002031 G-protein coupled receptor internalization(GO:0002031) regulation of protein binding(GO:0043393)
0.5 1.8 GO:0016199 axon midline choice point recognition(GO:0016199)
0.3 1.5 GO:0033198 response to ATP(GO:0033198)
0.2 2.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.2 0.7 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.2 0.7 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 1.8 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.2 1.1 GO:0090342 regulation of cell aging(GO:0090342)
0.1 1.3 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 0.3 GO:2000389 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.1 0.6 GO:0032534 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.1 1.8 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 0.4 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 1.6 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.4 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.6 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 1.5 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.7 GO:0006959 humoral immune response(GO:0006959)
0.0 1.1 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.7 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.5 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.4 GO:0021508 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0 0.8 GO:0007599 blood coagulation(GO:0007596) hemostasis(GO:0007599)
0.0 5.2 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 1.4 GO:0042391 regulation of membrane potential(GO:0042391)
0.0 0.1 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 1.6 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 0.4 GO:0051781 positive regulation of cell division(GO:0051781)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 8.1 GO:0005581 collagen trimer(GO:0005581)
0.1 0.7 GO:0005883 neurofilament(GO:0005883)
0.1 1.5 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.1 4.1 GO:0005882 intermediate filament(GO:0005882)
0.0 0.7 GO:0043679 axon terminus(GO:0043679)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 1.1 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.3 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.8 GO:0030424 axon(GO:0030424)
0.0 2.3 GO:0005912 adherens junction(GO:0005912)
0.0 1.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.5 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0035381 purinergic nucleotide receptor activity(GO:0001614) extracellular ATP-gated cation channel activity(GO:0004931) nucleotide receptor activity(GO:0016502) ATP-gated ion channel activity(GO:0035381)
0.2 0.7 GO:0030274 LIM domain binding(GO:0030274)
0.2 2.0 GO:0003785 actin monomer binding(GO:0003785)
0.2 0.6 GO:0004630 phospholipase D activity(GO:0004630)
0.1 1.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.8 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 0.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 1.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 5.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.7 GO:0031628 opioid receptor binding(GO:0031628)
0.1 0.4 GO:1901612 cardiolipin binding(GO:1901612)
0.1 1.6 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 4.2 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 2.3 GO:0045296 cadherin binding(GO:0045296)
0.0 0.4 GO:0048018 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.1 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.6 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.8 PID FOXM1 PATHWAY FOXM1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 0.4 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 1.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 1.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.1 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends