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Results for ebf3b

Z-value: 1.57

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Transcription factors associated with ebf3b

Gene Symbol Gene ID Gene Info
ebf3b
ENSDARG00000091287 EBF transcription factor 3b

Activity profile of ebf3b motif

Sorted Z-values of ebf3b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ebf3b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr7_-_32752138 7.42 ENSDART00000052383
cd81a
CD81 molecule a
chr4_+_8637319 5.81

chr22_+_11726312 5.69 ENSDART00000155366
krt96
keratin 96
chr25_+_30746445 5.30 ENSDART00000156916
lsp1
lymphocyte-specific protein 1
chr16_-_9978112 4.92 ENSDART00000149312
ncalda
neurocalcin delta a
chr6_+_54703206 4.65 ENSDART00000074605
pkp1b
plakophilin 1b
chr19_-_8961733 4.64 ENSDART00000039629
celf3a
cugbp, Elav-like family member 3a
chr21_-_37509454 4.30 ENSDART00000175126
fgfr4
fibroblast growth factor receptor 4
chr17_-_45383925 4.08

chr22_+_11745592 3.97 ENSDART00000140272
krt96
keratin 96
chr19_+_20183210 3.91 ENSDART00000164968
hoxa4a
homeobox A4a
chr11_-_38843219 3.67 ENSDART00000102827
p3h1
prolyl 3-hydroxylase 1
chr24_-_23797468 3.64 ENSDART00000080810
arxa
aristaless related homeobox a
chr13_+_371940 3.63 ENSDART00000013007
degs1
delta(4)-desaturase, sphingolipid 1
chr9_-_7695437 3.38 ENSDART00000102715
tuba8l3
tubulin, alpha 8 like 3
chr8_-_985673 3.37 ENSDART00000170737
smyd1b
SET and MYND domain containing 1b
chr6_+_2849460 3.34

chr7_-_52283383 3.13 ENSDART00000165649
tcf12
transcription factor 12
chr17_+_17935213 2.90 ENSDART00000104999
ccdc85ca
coiled-coil domain containing 85C, a
chr12_+_31558667 2.70 ENSDART00000152971
dnmbp
dynamin binding protein
chr2_-_39710140 2.61 ENSDART00000147821
spsb4a
splA/ryanodine receptor domain and SOCS box containing 4a
chr6_-_49674729 2.45 ENSDART00000112226
apcdd1l
adenomatosis polyposis coli down-regulated 1-like
chr7_-_18302231 2.37 ENSDART00000108938
msantd1
Myb/SANT-like DNA-binding domain containing 1
chr7_-_72127164 2.34 ENSDART00000176069
CABZ01057364.1
ENSDARG00000106736
chr10_-_5016621 2.34 ENSDART00000101414
hnrnpd
heterogeneous nuclear ribonucleoprotein D
chr18_+_9413588 2.33 ENSDART00000061886
sema3ab
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr10_+_33935945 2.26

chr8_-_15144533 2.19 ENSDART00000138855
bcar3
breast cancer anti-estrogen resistance 3
chr5_-_62116975 2.18 ENSDART00000144469
adora2b
adenosine A2b receptor
chr4_-_9007828 2.12 ENSDART00000153776
scube1
signal peptide, CUB domain, EGF-like 1
chr17_+_38619041 2.11 ENSDART00000145147
sptb
spectrin, beta, erythrocytic
chr7_-_33678058 2.08 ENSDART00000173513
pias1a
protein inhibitor of activated STAT, 1a
chr4_-_28346021 2.04 ENSDART00000178149
celsr1a
cadherin EGF LAG seven-pass G-type receptor 1a
chr21_+_4964891 1.99 ENSDART00000102572
thbs4b
thrombospondin 4b
chr21_+_21337628 1.94 ENSDART00000136325
rtn2b
reticulon 2b
chr9_-_31467299 1.86 ENSDART00000022204
zic5
zic family member 5 (odd-paired homolog, Drosophila)
chr13_-_31491759 1.80 ENSDART00000057432
six1a
SIX homeobox 1a
chr24_+_4946542 1.79 ENSDART00000045813
zic4
zic family member 4
chr10_-_31619761 1.75 ENSDART00000023575
robo3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr23_-_36319185 1.75 ENSDART00000139328
znf740b
zinc finger protein 740b
chr15_-_24934442 1.74 ENSDART00000127047
tusc5a
tumor suppressor candidate 5a
chr22_-_20361311 1.71

chr20_+_38298893 1.64 ENSDART00000022694
ehd3
EH-domain containing 3
chr8_+_39525254 1.63

chr8_+_24276667 1.56

chr11_-_30792331 1.56

chr19_+_11061965 1.53 ENSDART00000142975
si:ch1073-70f20.1
si:ch1073-70f20.1
chr20_+_6600184 1.53 ENSDART00000136567
tns3.2
tensin 3, tandem duplicate 2
chr8_-_38308535 1.52

chr24_+_4946079 1.51 ENSDART00000114537
zic4
zic family member 4
chr22_-_23238714 1.51 ENSDART00000054807
lhx9
LIM homeobox 9
chr22_+_11726429 1.50 ENSDART00000155366
krt96
keratin 96
chr22_+_11745657 1.49 ENSDART00000140272
krt96
keratin 96
chr11_-_38278666 1.48

chr13_-_40190349 1.47 ENSDART00000009343
pyroxd2
pyridine nucleotide-disulphide oxidoreductase domain 2
chr18_+_6692267 1.47

chr8_+_24276581 1.42

chr16_-_38604326 1.39 ENSDART00000109124
rspo2
R-spondin 2
chr11_-_22143133 1.37 ENSDART00000159681
tfeb
transcription factor EB
chr12_+_34662699 1.36 ENSDART00000153097
slc38a10
solute carrier family 38, member 10
chr6_+_45930323 1.32 ENSDART00000154896
rbp7b
retinol binding protein 7b, cellular
chr16_-_32059848 1.31 ENSDART00000138701
gstk1
glutathione S-transferase kappa 1
chr4_-_38406131 1.31

chr20_+_6600246 1.28 ENSDART00000136567
tns3.2
tensin 3, tandem duplicate 2
chr11_-_27253835 1.25 ENSDART00000065889
wnt7aa
wingless-type MMTV integration site family, member 7Aa
chr20_+_38298755 1.22 ENSDART00000022694
ehd3
EH-domain containing 3
chr3_+_43010408 1.21 ENSDART00000169061
CU138533.1
ENSDARG00000099842
chr2_-_39709905 1.11 ENSDART00000147821
spsb4a
splA/ryanodine receptor domain and SOCS box containing 4a
chr13_+_28723589 1.03

chr5_-_18548376 1.01 ENSDART00000133330
fam214b
family with sequence similarity 214, member B
chr11_+_7570027 0.96 ENSDART00000091550
adgrl2a
adhesion G protein-coupled receptor L2a
chr7_+_39139248 0.96 ENSDART00000165594
CT030188.1
ENSDARG00000099385
chr10_+_8697704 0.95 ENSDART00000123131
pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
chr22_-_23518719 0.94 ENSDART00000161253
crb1
crumbs family member 1, photoreceptor morphogenesis associated
chr7_+_54347388 0.93 ENSDART00000158898
fgf4
fibroblast growth factor 4
chr16_+_40396454 0.89 ENSDART00000121711
BX072576.2
ENSDARG00000090181
chr4_-_48343469 0.83 ENSDART00000121664
znf1128
zinc finger protein 1128
chr13_+_46487890 0.82

chr21_-_37509396 0.82 ENSDART00000100286
fgfr4
fibroblast growth factor receptor 4
chr4_+_67334424 0.77 ENSDART00000136092
si:ch211-209j12.3
si:ch211-209j12.3
chr9_-_37114484 0.76 ENSDART00000059756
ralba
v-ral simian leukemia viral oncogene homolog Ba (ras related)
chr3_-_28534446 0.76 ENSDART00000151670
fbxl16
F-box and leucine-rich repeat protein 16
chr18_+_17552191 0.75

chr25_-_21618526 0.75 ENSDART00000152011
DOCK4 (1 of many)
dedicator of cytokinesis 4
chr11_+_7570097 0.72 ENSDART00000091550
adgrl2a
adhesion G protein-coupled receptor L2a
chr17_-_43409302 0.72 ENSDART00000156206
itpk1b
inositol-tetrakisphosphate 1-kinase b
chr22_-_2828572 0.70

chr1_-_52869817 0.68 ENSDART00000162025
ENSDART00000100788
commd1
copper metabolism (Murr1) domain containing 1
chr24_-_23797593 0.64 ENSDART00000080810
arxa
aristaless related homeobox a
chr17_-_43409222 0.56 ENSDART00000156033
itpk1b
inositol-tetrakisphosphate 1-kinase b
chr3_-_55397643 0.55 ENSDART00000176127
axin2
axin 2 (conductin, axil)
chr3_-_19847002 0.54

chr3_-_55397592 0.54 ENSDART00000176127
axin2
axin 2 (conductin, axil)
chr4_-_9007909 0.51 ENSDART00000164632
scube1
signal peptide, CUB domain, EGF-like 1
chr18_+_9413668 0.48 ENSDART00000061886
sema3ab
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr15_+_2495106 0.46

chr9_-_31467205 0.44 ENSDART00000022204
zic5
zic family member 5 (odd-paired homolog, Drosophila)
chr7_+_38540519 0.43 ENSDART00000052322
zgc:110699
zgc:110699
chr8_+_31812204 0.40 ENSDART00000077053
plcxd3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr4_-_29003925 0.36 ENSDART00000111294
zgc:174315
zgc:174315
chr25_+_34707504 0.31

chr7_+_60746590 0.29 ENSDART00000115355
nwd2
NACHT and WD repeat domain containing 2
chr17_+_30506560 0.27

chr25_-_23977017 0.25 ENSDART00000040410
th
tyrosine hydroxylase
chr12_+_6161471 0.24 ENSDART00000163828
BX248126.1
ENSDARG00000096552
chr23_+_35573740 0.24 ENSDART00000046268
pmelb
premelanosome protein b
chr16_-_42857240 0.21

chr21_-_36495488 0.20

chr4_+_29775735 0.20 ENSDART00000166510
BX530097.1
ENSDARG00000104762
chr6_+_7093685 0.18 ENSDART00000177226
dzip1
DAZ interacting zinc finger protein 1
chr23_-_35904414 0.15 ENSDART00000103150
calcoco1a
calcium binding and coiled-coil domain 1a
chr7_+_39139117 0.13 ENSDART00000165594
CT030188.1
ENSDARG00000099385
chr10_+_33936073 0.10

chr15_+_2495159 0.08

chr8_-_17692185 0.07

chr1_+_15855776 0.01 ENSDART00000048855
mtus1b
microtubule associated tumor suppressor 1b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0050810 regulation of steroid biosynthetic process(GO:0050810)
1.1 4.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.8 4.7 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.8 1.5 GO:0097377 interneuron axon guidance(GO:0097376) spinal cord interneuron axon guidance(GO:0097377) dorsal spinal cord interneuron axon guidance(GO:0097378)
0.6 2.8 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.5 3.3 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.5 2.0 GO:0035989 tendon development(GO:0035989)
0.4 3.1 GO:0048769 sarcomerogenesis(GO:0048769)
0.4 1.8 GO:0016199 axon midline choice point recognition(GO:0016199)
0.3 4.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.3 2.3 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.3 1.8 GO:0014856 skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857)
0.2 2.2 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.2 2.2 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.2 0.7 GO:2000008 negative regulation of sodium ion transmembrane transport(GO:1902306) regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.2 3.7 GO:0032963 collagen metabolic process(GO:0032963) multicellular organismal macromolecule metabolic process(GO:0044259)
0.1 0.9 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.1 2.1 GO:0016925 protein sumoylation(GO:0016925)
0.1 1.4 GO:0033336 caudal fin development(GO:0033336)
0.1 1.4 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 5.8 GO:0021782 glial cell development(GO:0021782)
0.1 0.3 GO:0009713 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.1 2.9 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 2.1 GO:0030835 regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835) actin filament capping(GO:0051693)
0.1 1.1 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 1.4 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 1.3 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 2.6 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 1.3 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 1.7 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.9 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 2.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0032438 melanosome organization(GO:0032438)
0.0 0.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 3.4 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.8 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 2.8 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.0 2.7 GO:0060271 cilium morphogenesis(GO:0060271)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0008091 spectrin(GO:0008091)
0.3 3.1 GO:0031430 M band(GO:0031430)
0.2 4.7 GO:0030057 desmosome(GO:0030057)
0.2 2.9 GO:0060170 ciliary membrane(GO:0060170)
0.1 12.6 GO:0005882 intermediate filament(GO:0005882)
0.1 4.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 2.0 GO:0016528 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)
0.0 2.9 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 2.7 GO:0005911 cell-cell junction(GO:0005911)
0.0 4.3 GO:0016604 nuclear body(GO:0016604)
0.0 3.7 GO:0030424 axon(GO:0030424)
0.0 2.6 GO:0009986 cell surface(GO:0009986)
0.0 4.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.3 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 3.3 GO:0043235 receptor complex(GO:0043235)
0.0 3.4 GO:0005874 microtubule(GO:0005874)
0.0 0.2 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 2.8 GO:0030054 cell junction(GO:0030054)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.7 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.4 2.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.3 5.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.3 2.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 2.8 GO:0038191 neuropilin binding(GO:0038191)
0.2 3.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 5.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.8 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 1.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 4.7 GO:0045296 cadherin binding(GO:0045296)
0.1 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 2.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.3 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 1.3 GO:0005109 frizzled binding(GO:0005109)
0.0 0.8 GO:0019003 GDP binding(GO:0019003)
0.0 10.9 GO:0005198 structural molecule activity(GO:0005198)
0.0 3.6 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen(GO:0016705)
0.0 1.4 GO:0008201 heparin binding(GO:0008201)
0.0 4.8 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 13.2 GO:0005509 calcium ion binding(GO:0005509)
0.0 2.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.4 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 24.1 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 4.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 6.0 PID FGF PATHWAY FGF signaling pathway
0.0 3.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.2 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.0 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.3 2.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 3.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 0.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 3.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 2.2 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.1 1.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 2.3 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)