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Results for egr1

Z-value: 0.55

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Transcription factors associated with egr1

Gene Symbol Gene ID Gene Info
ENSDARG00000037421 early growth response 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
egr1dr10_dc_chr14_-_21039158_21039162-0.253.6e-01Click!

Activity profile of egr1 motif

Sorted Z-values of egr1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of egr1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_+_48188313 0.87

chr25_-_35760878 0.78 ENSDART00000121786
histone 1, H4, like
chr25_+_35765309 0.76 ENSDART00000128547
histone 1, H4, like
chr19_-_6274458 0.73 ENSDART00000151405
Ets2 repressor factor
chr14_+_14850200 0.70 ENSDART00000167966
zgc:158852
chr25_-_34634503 0.68 ENSDART00000157370
Histone H3.2
chr23_-_22146031 0.66 ENSDART00000054362
polyhomeotic homolog 2a (Drosophila)
chr7_-_6273677 0.64 ENSDART00000173419
si:ch73-368j24.1
chr10_-_34058331 0.60 ENSDART00000046599
zygote arrest 1-like
chr25_+_1511300 0.59 ENSDART00000093277
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr19_-_6274040 0.53 ENSDART00000140347
ENSDART00000092656
Ets2 repressor factor
KN150256v1_-_9560 0.51

chr23_-_22145900 0.46 ENSDART00000132343
polyhomeotic homolog 2a (Drosophila)
chr19_-_6274169 0.46 ENSDART00000140347
ENSDART00000092656
Ets2 repressor factor
chr7_-_20358730 0.45 ENSDART00000170422
si:dkey-19b23.8
chr7_+_5846555 0.42 ENSDART00000083397
histone 1, H4, like
chr20_-_54591757 0.41 ENSDART00000136779
ectonucleoside triphosphate diphosphohydrolase 5b
chr6_+_48188448 0.40

chr15_-_17163526 0.39 ENSDART00000101724
v-mos Moloney murine sarcoma viral oncogene homolog
chr7_-_52223087 0.38 ENSDART00000129769
cingulin-like 1
chr23_-_29630277 0.37 ENSDART00000138021
retinol binding protein 7a, cellular
chr22_-_62082 0.37 ENSDART00000166010
ENSDART00000125700
mitochondrial ribosomal protein L20
chr21_+_19332231 0.37 ENSDART00000168728
betacellulin, epidermal growth factor family member
chr19_+_1298795 0.36 ENSDART00000113368
ring finger protein 5
chr5_+_65491173 0.34 ENSDART00000050847
ENSDART00000172117
glycine decarboxylase
chr5_+_37120604 0.34 ENSDART00000076083
CDC42 effector protein (Rho GTPase binding) 2
chr16_-_26258657 0.34 ENSDART00000157787
lipase, hormone-sensitive b
chr16_-_12621624 0.33 ENSDART00000155829
cytochrome c oxidase subunit VIb polypeptide 2
chr1_-_17000212 0.33 ENSDART00000146258
cilia and flagella associated protein 97
chr21_+_19332111 0.33 ENSDART00000158471
betacellulin, epidermal growth factor family member
chr19_+_7235553 0.32 ENSDART00000160894
bromodomain containing 2a
chr16_-_6881218 0.32 ENSDART00000149070
myelin basic protein b
chr21_-_804453 0.31

chr12_-_29118423 0.31 ENSDART00000153175
si:ch211-214e3.5
chr9_-_41608298 0.31

chr6_+_48188520 0.31

chr7_-_24373315 0.30 ENSDART00000048921
GP1 homolog, RAB6A GEF complex partner 1
chr1_-_48790379 0.30 ENSDART00000150842
up-regulated during skeletal muscle growth 5 homolog (mouse)
chr16_-_5205600 0.30 ENSDART00000148955
branched chain keto acid dehydrogenase E1, beta polypeptide
chr2_+_35898064 0.28 ENSDART00000004277
laminin, gamma 1
chr24_+_24777962 0.27 ENSDART00000065288
phosphate cytidylyltransferase 1, choline, beta a
chr1_-_51870424 0.27 ENSDART00000135636
aspartoacylase (aminocyclase) 3, tandem duplicate 1
chr8_-_53584884 0.27

chr24_+_3296536 0.27 ENSDART00000147468
3-hydroxybutyrate dehydrogenase, type 1
chr19_-_6274237 0.26 ENSDART00000151405
Ets2 repressor factor
chr12_-_37274632 0.25 ENSDART00000152951
CDC42 effector protein (Rho GTPase binding) 4b
chr3_+_14151127 0.25 ENSDART00000162023
phospholipid phosphatase related 2a
chr14_+_891448 0.25 ENSDART00000021346
ADP-ribosylation factor-like 3, like 2
chr10_+_45184723 0.24 ENSDART00000160536
glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b
chr8_-_49227143 0.24

chr3_-_45358502 0.24 ENSDART00000168108
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a
chr6_+_42340776 0.24 ENSDART00000015277
glutathione peroxidase 1b
chr5_+_65491288 0.24 ENSDART00000050847
ENSDART00000172117
glycine decarboxylase
chr20_+_13998066 0.24 ENSDART00000007744
solute carrier family 30 (zinc transporter), member 1a
chr23_+_2614658 0.23

chr7_+_28453707 0.23 ENSDART00000173947
coiled-coil domain containing 102A
chr14_-_15393962 0.23 ENSDART00000161123
ENSDART00000167146
neuralized E3 ubiquitin protein ligase 1B
chr19_-_25843036 0.22 ENSDART00000036854
glucocorticoid induced 1
chr8_+_8889274 0.22 ENSDART00000142075
Pim-2 proto-oncogene, serine/threonine kinase
chr19_-_7235125 0.21

chr2_+_38959335 0.21 ENSDART00000109219
RAS (RAD and GEM)-like GTP binding 2
chr3_-_37429712 0.21 ENSDART00000161401
ADP-ribosylation factor 2a
chr19_-_25842574 0.21 ENSDART00000036854
glucocorticoid induced 1
chr7_-_24724452 0.21 ENSDART00000173791
REST corepressor 2
chr12_-_2638179 0.21

chr9_-_55878791 0.21

chr24_+_24778026 0.20 ENSDART00000065288
phosphate cytidylyltransferase 1, choline, beta a
chr3_-_5318012 0.20 ENSDART00000137105
myosin, heavy chain 9b, non-muscle
chr6_-_18019342 0.20 ENSDART00000154941
TEN1 CST complex subunit
chr2_+_38288916 0.19 ENSDART00000042100
homeobox and leucine zipper encoding a
chr8_+_20406797 0.19 ENSDART00000016422
MAP kinase interacting serine/threonine kinase 2b
chr18_+_15137751 0.19 ENSDART00000168639
cryptochrome circadian clock 1ab
chr2_+_24046083 0.19 ENSDART00000047073
oxidative stress responsive 1a
chr2_+_50327729 0.19 ENSDART00000097939
zinc finger, CCHC domain containing 2
chr19_-_2147899 0.19 ENSDART00000020497
sorting nexin 13
chr8_-_25889113 0.18

chr11_+_25058986 0.18 ENSDART00000122249
topoisomerase (DNA) I, like
chr1_-_17000175 0.18 ENSDART00000146258
cilia and flagella associated protein 97
chr6_-_12972427 0.18 ENSDART00000147851
eukaryotic translation elongation factor 1 beta 2
chr18_+_36620417 0.18 ENSDART00000088421
CLK4-associating serine/arginine rich protein
chr20_+_32620786 0.18 ENSDART00000147319
sex comb on midleg-like 4 (Drosophila)
chr14_+_17092009 0.18 ENSDART00000129838
ring finger protein 212
chr16_-_5205633 0.18 ENSDART00000082071
branched chain keto acid dehydrogenase E1, beta polypeptide
chr17_+_15975348 0.17 ENSDART00000160742
calmin
chr22_+_37688695 0.17 ENSDART00000174664
ENSDART00000178200
ENSDARG00000108910
chr8_-_18582786 0.17 ENSDART00000089172
coproporphyrinogen oxidase
chr7_-_10318801 0.16 ENSDART00000172761
ENSDART00000170476
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chr15_+_14925920 0.16

chr22_+_24112851 0.16

chr16_-_14075348 0.16 ENSDART00000138304
si:dkey-85k15.4
chr11_-_2524380 0.15 ENSDART00000114079
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr7_+_22710714 0.15 ENSDART00000122449
cyclin B3
chr7_+_41060622 0.15 ENSDART00000160143
GRB2 associated, regulator of MAPK1
chr22_+_37689055 0.15

chr17_-_1524813 0.15 ENSDART00000112803
WD repeat domain 20a
chr18_+_5637539 0.15

chr5_+_37120548 0.15 ENSDART00000076083
CDC42 effector protein (Rho GTPase binding) 2
chr20_+_27188382 0.14 ENSDART00000062094
transmembrane protein 251
chr21_-_776741 0.14

chr20_+_38555185 0.14 ENSDART00000020153
aarF domain containing kinase 3
chr11_+_38449192 0.14 ENSDART00000041800
eph receptor A8
KN150034v1_+_1223 0.14

chr2_-_44491143 0.14 ENSDART00000084174
ligase I, DNA, ATP-dependent
chr8_-_49227286 0.13

chr18_-_39797167 0.13 ENSDART00000169916
Dmx-like 2
chr17_+_1525358 0.13

chr24_+_37800773 0.13 ENSDART00000137017
H3 histone, family 3D
chr23_+_25929969 0.13 ENSDART00000145426
hepatocyte nuclear factor 4, alpha
chr9_+_33310981 0.13

chr8_+_2583789 0.13 ENSDART00000143242
nuclear apoptosis inducing factor 1
chr16_+_19223683 0.13 ENSDART00000115263
ENSDART00000114954
Rap guanine nucleotide exchange factor (GEF) 5b
chr14_+_29428950 0.13 ENSDART00000105898
ENSDARG00000071567
chr15_-_21003820 0.12 ENSDART00000152371
ubiquitin specific peptidase 2a
chr9_+_52256434 0.12 ENSDART00000125850
CD302 molecule
chr18_+_45866556 0.12 ENSDART00000024615
arginyl aminopeptidase like 1
chr22_+_37688988 0.12

chr7_+_41060426 0.12 ENSDART00000005127
GRB2 associated, regulator of MAPK1
KN149779v1_-_14268 0.12 ENSDART00000162865
intraflagellar transport 27 homolog (Chlamydomonas)
chr24_+_37518715 0.12 ENSDART00000138264
si:ch211-183d21.1
chr14_+_300285 0.12 ENSDART00000159949
WD repeat domain 1
chr5_+_6308337 0.12 ENSDART00000048201
SMAD family member 4
chr17_+_26736073 0.11 ENSDART00000163886
La ribonucleoprotein domain family, member 1B
chr23_-_33692244 0.11

chr2_+_17042235 0.11 ENSDART00000017852
UBX domain protein 7
chr7_-_20358696 0.11 ENSDART00000170422
si:dkey-19b23.8
chr7_-_24373258 0.11 ENSDART00000172282
GP1 homolog, RAB6A GEF complex partner 1
chr20_-_45757288 0.11 ENSDART00000124582
ENSDART00000100290
N-ethylmaleimide-sensitive factor attachment protein, beta b
chr8_-_53508979 0.10 ENSDART00000158789
choline dehydrogenase
chr7_-_20358841 0.10 ENSDART00000170422
si:dkey-19b23.8
chr7_+_45747395 0.10 ENSDART00000163991
cyclin E1
chr23_-_31719203 0.10 ENSDART00000148122
serum/glucocorticoid regulated kinase 1
chr2_+_24045890 0.10 ENSDART00000047073
oxidative stress responsive 1a
chr3_-_5318147 0.10 ENSDART00000137105
myosin, heavy chain 9b, non-muscle
chr25_+_29245654 0.10 ENSDART00000073478
bromodomain containing 1b
chr16_+_14075878 0.09 ENSDART00000059926
zgc:162509
chr6_+_48188609 0.09

chr23_+_25930072 0.09 ENSDART00000124103
hepatocyte nuclear factor 4, alpha
chr5_+_37120337 0.09 ENSDART00000076083
CDC42 effector protein (Rho GTPase binding) 2
chr5_+_36431907 0.09 ENSDART00000045036
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr10_-_32907793 0.09 ENSDART00000134255
tripartite motif containing 37
chr11_-_37613237 0.09 ENSDART00000102868
ethanolamine kinase 2
chr20_+_32620873 0.09 ENSDART00000147319
sex comb on midleg-like 4 (Drosophila)
chr15_-_4491042 0.09 ENSDART00000157273
transcription factor Dp-2
chr11_+_36984616 0.09 ENSDART00000169804
interleukin 17 receptor C
chr3_+_51430252 0.09 ENSDART00000159493
BAI1-associated protein 2a
chr23_-_32173435 0.09 ENSDART00000044658
LETM1 domain containing 1
chr1_+_39357275 0.09

chr2_-_24947660 0.09 ENSDART00000113356
ENSDART00000163038
CREB regulated transcription coactivator 1a
KN150034v1_+_1158 0.08

chr15_+_17471018 0.08 ENSDART00000145216
ribosomal protein S6 kinase b, polypeptide 1b
chr12_-_20181519 0.08 ENSDART00000040909
rhomboid 5 homolog 1b (Drosophila)
chr7_-_24373522 0.08 ENSDART00000048921
GP1 homolog, RAB6A GEF complex partner 1
chr22_+_37688585 0.08 ENSDART00000174664
ENSDART00000178200
ENSDARG00000108910
chr16_-_14075931 0.08

chr23_+_2847589 0.08 ENSDART00000156954
phospholipase C, gamma 1
chr15_-_17163487 0.08 ENSDART00000101724
v-mos Moloney murine sarcoma viral oncogene homolog
chr7_-_20358897 0.08 ENSDART00000170422
si:dkey-19b23.8
chr1_-_9789386 0.08 ENSDART00000040116
trinucleotide repeat containing 5
chr11_+_269859 0.08 ENSDART00000109091
methyltransferase like 1
chr13_+_290930 0.08 ENSDART00000017854
leucine-rich, glioma inactivated 1a
chr18_+_5456221 0.08

chr5_+_36010806 0.07 ENSDART00000097684
neuro-oncological ventral antigen 1
chr7_+_9080691 0.07 ENSDART00000104536
chondroitin sulfate synthase 1
chr11_+_25058714 0.07 ENSDART00000065949
topoisomerase (DNA) I, like
chr12_-_4212149 0.07 ENSDART00000059298
zgc:92313
chr9_-_33116897 0.07

chr18_-_19114558 0.07 ENSDART00000177621
DENN/MADD domain containing 4A
chr24_-_37800277 0.07 ENSDART00000141414
zgc:112185
chr5_+_35913494 0.07 ENSDART00000013590
wingless-type MMTV integration site family, member 11
chr19_+_341775 0.07 ENSDART00000151013
endosulfine alpha a
chr15_+_14925529 0.07 ENSDART00000166250
ENSDARG00000103638
chr15_-_23484754 0.07 ENSDART00000148840
lysine (K)-specific methyltransferase 2A
chr11_+_44916426 0.06

chr2_-_54909304 0.06 ENSDART00000100103
acyl-CoA synthetase short-chain family member 2 like
chr2_-_55565099 0.06 ENSDART00000149062
RAB8A, member RAS oncogene family
chr15_+_42441012 0.06 ENSDART00000089694
T-cell lymphoma invasion and metastasis 1b
chr5_-_1734159 0.05 ENSDART00000145781
ENSDARG00000094300
chr2_+_21698627 0.05 ENSDART00000133228
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like b
chr12_-_954375 0.05 ENSDART00000054367
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2b
chr9_-_54459836 0.05 ENSDART00000085253
midline 1
chr24_-_42193714 0.05

chr9_+_52256395 0.05 ENSDART00000125850
CD302 molecule
chr20_+_32620937 0.05 ENSDART00000147319
sex comb on midleg-like 4 (Drosophila)
chr6_+_12972934 0.04 ENSDART00000036927
NADH dehydrogenase (ubiquinone) Fe-S protein 1
chr18_+_15137711 0.04 ENSDART00000128609
cryptochrome circadian clock 1ab
chr25_-_29245587 0.04

chr3_-_23620163 0.04

chr9_-_30553051 0.04 ENSDART00000147030
synaptotagmin-like 5
chr1_-_44239584 0.04 ENSDART00000137216
transmembrane protein 176
chr19_-_2148053 0.04 ENSDART00000020497
sorting nexin 13
chr2_-_1752776 0.04 ENSDART00000126566
solute carrier family 22, member 23
chr16_-_13704905 0.04 ENSDART00000060004
ntl-dependent gene 5
chr21_+_8106096 0.03 ENSDART00000011096
nuclear receptor subfamily 6, group A, member 1b
chr23_+_24557956 0.03

chr18_-_5689483 0.03 ENSDART00000129459
spermatogenesis associated 5-like 1
chr6_-_25081182 0.03 ENSDART00000161585
leucine rich repeat containing 8 family, member Db
chr20_+_46795264 0.03 ENSDART00000167398
WD repeat domain 26b
chr7_-_45747112 0.03 ENSDART00000172591
zgc:162297
chr14_+_38505984 0.03 ENSDART00000144599
heterogeneous nuclear ribonucleoprotein A0b
chr15_+_17470879 0.03 ENSDART00000081059
ribosomal protein S6 kinase b, polypeptide 1b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:1902102 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.1 0.3 GO:0071364 response to epidermal growth factor(GO:0070849) cellular response to epidermal growth factor stimulus(GO:0071364)
0.1 0.7 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.1 0.2 GO:1990359 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.1 0.8 GO:0031268 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.3 GO:0010269 response to selenium ion(GO:0010269)
0.1 0.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:0071632 optomotor response(GO:0071632)
0.0 0.3 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.4 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.5 GO:0007584 response to nutrient(GO:0007584)
0.0 0.1 GO:1902908 regulation of melanosome transport(GO:1902908)
0.0 0.2 GO:0071333 cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.0 0.1 GO:0051103 DNA ligation(GO:0006266) DNA ligation involved in DNA repair(GO:0051103)
0.0 0.1 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.1 GO:0035474 selective angioblast sprouting(GO:0035474)
0.0 0.2 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.2 GO:1904357 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 2.0 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.2 GO:0035999 folic acid-containing compound biosynthetic process(GO:0009396) tetrahydrofolate interconversion(GO:0035999)
0.0 0.1 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.0 0.1 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.1 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.2 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.2 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.0 0.2 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.2 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.0 0.1 GO:2000251 regulation of actin cytoskeleton reorganization(GO:2000249) positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0034066 RIC1-RGP1 guanyl-nucleotide exchange factor complex(GO:0034066)
0.1 0.5 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 0.2 GO:1990879 CST complex(GO:1990879)
0.1 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 1.1 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.3 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 2.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.1 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.0 0.1 GO:0016234 inclusion body(GO:0016234)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.2 0.6 GO:1903231 mRNA binding involved in posttranscriptional gene silencing(GO:1903231)
0.1 0.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.2 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.6 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.2 GO:0004691 AMP-activated protein kinase activity(GO:0004679) cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 2.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.7 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.1 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells