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DANIO-CODE

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Results for ehf

Z-value: 1.41

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Transcription factors associated with ehf

Gene Symbol Gene ID Gene Info
ENSDARG00000052115 ets homologous factor

Activity profile of ehf motif

Sorted Z-values of ehf motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ehf

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_-_46426385 4.71 ENSDART00000141331
si:ch73-59c19.1
chr19_-_27093095 4.50

chr10_-_17214368 3.96

chr17_-_45021393 3.05

chr24_-_9857510 2.82 ENSDART00000136274
si:ch211-146l10.7
chr1_-_21961282 2.75 ENSDART00000171830
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr25_+_4888647 2.74 ENSDART00000165933
ENSDART00000159537
histone deacetylase 10
KN150623v1_+_258 2.73

chr1_-_7869105 2.59 ENSDART00000147763
zgc:112980
chr22_-_17627900 2.59 ENSDART00000138483
si:ch73-243b8.4
chr8_-_49227286 2.34

chr8_-_49227232 2.31

chr3_-_39117855 2.29 ENSDART00000102678
N-myristoyltransferase 1a
chr2_+_37224986 2.19 ENSDART00000138952
apolipoprotein Da, duplicate 2
chr5_-_15971338 2.19 ENSDART00000110437
piwi-like RNA-mediated gene silencing 2
chr16_-_29755471 2.08 ENSDART00000133965
sodium channel modifier 1
chr25_-_3619590 2.07 ENSDART00000037973
MORC family CW-type zinc finger 2
chr4_-_14208573 2.06 ENSDART00000015134
twinfilin actin-binding protein 1b
chr22_-_17627831 2.06 ENSDART00000138483
si:ch73-243b8.4
chr1_+_18956542 1.97 ENSDART00000054575
transmembrane protein 192
chr24_+_31522539 1.96 ENSDART00000126380
cyclic nucleotide binding domain containing 1
chr1_+_18956648 1.94 ENSDART00000054575
transmembrane protein 192
chr14_-_6901209 1.93 ENSDART00000167994
ENSDART00000166532
storkhead box 2b
chr1_-_40671573 1.92 ENSDART00000074777
ENSDART00000158114
huntingtin
chr20_-_23354440 1.90 ENSDART00000103365
OCIA domain containing 1
chr17_-_25313024 1.84 ENSDART00000082324
zona pellucida protein C
chr23_-_32267833 1.82

chr23_+_25952724 1.82 ENSDART00000124963
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr16_-_25318413 1.81 ENSDART00000058943
ENSDARG00000040280
chr17_-_9806363 1.81 ENSDART00000021942
e2f-associated phosphoprotein
chr3_+_27582277 1.80 ENSDART00000019004
Rho GDP dissociation inhibitor (GDI) gamma
chr9_+_29709931 1.76 ENSDART00000078904
ENSDART00000150164
ferredoxin 1
chr1_+_32825950 1.74 ENSDART00000018472
charged multivesicular body protein 2Bb
chr19_+_43468369 1.72 ENSDART00000165202
pumilio RNA-binding family member 1
chr10_-_1933874 1.70 ENSDART00000101023
teratocarcinoma-derived growth factor 1
chr17_+_24791024 1.67 ENSDART00000130871
speedy/RINGO cell cycle regulator family member A
chr10_+_10354740 1.67 ENSDART00000142895
ubiquitin related modifier 1
chr1_+_157840 1.66 ENSDART00000152205
ENSDART00000160843
cullin 4A
chr24_-_9874069 1.66 ENSDART00000176344
si:ch211-146l10.7
chr15_+_38397715 1.64 ENSDART00000142403
si:dkey-24p1.6
chr13_-_9034919 1.63 ENSDART00000135373
si:dkey-33c12.4
chr7_-_48532462 1.63 ENSDART00000015884
milk fat globule-EGF factor 8 protein a
chr8_+_8605240 1.61 ENSDART00000075624
ubiquitin specific peptidase 11
chr23_+_25952958 1.60 ENSDART00000124963
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr23_+_25952913 1.59 ENSDART00000124963
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr5_+_24580551 1.59 ENSDART00000134526
zgc:193538
chr11_+_2527564 1.59 ENSDART00000175330
DnaJ (Hsp40) homolog, subfamily C, member 14
chr6_-_3347207 1.58 ENSDART00000151416
si:ch1073-342h5.2
chr18_-_26815192 1.57 ENSDART00000008013
SEC11 homolog A, signal peptidase complex subunit
chr23_+_33792145 1.56 ENSDART00000024695
DAZ associated protein 2
chr5_+_19429620 1.55 ENSDART00000088819
ankyrin repeat domain 13A
chr5_+_9579430 1.55 ENSDART00000109236
ENSDARG00000075416
chr17_+_24790812 1.53 ENSDART00000082251
speedy/RINGO cell cycle regulator family member A
chr13_-_37340209 1.52

chr10_-_180603 1.51

chr17_+_25313170 1.50 ENSDART00000157309
transmembrane protein 54a
chr7_-_26332194 1.49 ENSDART00000099003
phospholipid scramblase 3b
chr7_+_69290790 1.49 ENSDART00000109507
Rap1 GTPase-GDP dissociation stimulator 1
chr3_-_32457708 1.49

chr7_-_6334676 1.47 ENSDART00000081359
zgc:110425
chr20_+_34084660 1.47 ENSDART00000061751
zona pellucida glycoprotein 3a, tandem duplicate 2
chr24_-_37450413 1.47 ENSDART00000056303
TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)
chr23_+_17596504 1.45 ENSDART00000002714
solute carrier family 17 (vesicular nucleotide transporter), member 9b
chr16_-_52847564 1.44 ENSDART00000147236
antizyme inhibitor 1a
chr10_-_1933761 1.44 ENSDART00000101023
teratocarcinoma-derived growth factor 1
chr25_-_21409895 1.43 ENSDART00000010706
inner mitochondrial membrane peptidase subunit 2
chr5_+_40235387 1.43 ENSDART00000147767
si:dkey-3h3.3
chr7_+_73598715 1.43 ENSDART00000109720
zgc:163061
chr14_-_20594454 1.42 ENSDART00000132499
iduronate 2-sulfatase
chr19_+_43928043 1.41 ENSDART00000113031
WAS protein family, member 2
chr15_-_29393378 1.41 ENSDART00000114492
si:dkey-52l18.4
chr3_+_17901295 1.41 ENSDART00000035531
methyltransferase like 26
chr20_-_18482817 1.40 ENSDART00000159636
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
chr1_-_52833379 1.40 ENSDART00000143349
zgc:66455
chr7_-_6618142 1.40 ENSDART00000002949
ENSDARG00000045199
chr24_-_23570846 1.38 ENSDART00000084954
ENSDART00000004013
ENSDART00000129028
phosphatidylinositol glycan anchor biosynthesis, class N
chr8_+_41004169 1.37

chr14_-_20940726 1.37 ENSDART00000129743
si:ch211-175m2.5
chr8_+_41003546 1.37 ENSDART00000129344
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr24_+_37450437 1.36 ENSDART00000141771
N-acetylglucosamine-1-phosphate transferase, gamma subunit
chr6_-_40715613 1.35 ENSDART00000153702
si:ch211-157b11.12
chr16_+_43464824 1.34 ENSDART00000032778
ring finger protein 144B
chr11_+_13118866 1.33 ENSDART00000123257
MAP kinase interacting serine/threonine kinase 1
chr11_-_25615491 1.33 ENSDART00000145655
transmembrane protein 51b
chr18_-_49291686 1.32 ENSDART00000174038
si:zfos-464b6.2
chr14_+_35084220 1.31 ENSDART00000171809
synaptotagmin-like 4
chr15_+_38397897 1.31 ENSDART00000142403
si:dkey-24p1.6
chr20_+_29685379 1.31 ENSDART00000178617
ADAM metallopeptidase domain 17b
chr25_-_25480657 1.30 ENSDART00000067138
hypermethylated in cancer 1 like
chr20_+_24047842 1.28 ENSDART00000128616
ENSDART00000144195
caspase 8 associated protein 2
chr7_-_57876365 1.27 ENSDART00000073635
neutral sphingomyelinase (N-SMase) activation associated factor
chr1_+_46474561 1.27 ENSDART00000167051
carbonyl reductase 1
chr2_-_41888389 1.25

chr13_+_25418877 1.25 ENSDART00000169199
SEC23 interacting protein
chr24_-_37438115 1.24 ENSDART00000003789
3-phosphoinositide dependent protein kinase 1b
chr21_-_43654780 1.24 ENSDART00000142733
si:dkey-229d11.5
chr5_-_56953587 1.23 ENSDART00000167892
zgc:193711
chr20_-_3220475 1.23 ENSDART00000123331
serine peptidase inhibitor, Kunitz type 1 b
chr8_-_47339228 1.23 ENSDART00000060853
peroxisomal biogenesis factor 10
chr17_-_35331055 1.22 ENSDART00000063437
ADAM metallopeptidase domain 17a
chr17_-_31195299 1.21 ENSDART00000086511
RNA pseudouridylate synthase domain containing 2
chr3_-_36298676 1.21 ENSDART00000157950
rogdi homolog (Drosophila)
chr5_+_51186708 1.20 ENSDART00000165276
PAP associated domain containing 4
chr19_+_47918720 1.20 ENSDART00000157886
zgc:114119
chr4_-_12979905 1.19 ENSDART00000150674
transmembrane BAX inhibitor motif containing 4
chr13_-_25277861 1.19 ENSDART00000002741
inositol 1,4,5-trisphosphate receptor interacting protein
chr7_-_13416823 1.19 ENSDART00000056893
programmed cell death 7
chr3_-_58400454 1.18 ENSDART00000052179
cerebellar degeneration-related protein 2a
chr20_+_31036284 1.18 ENSDART00000153344
superoxide dismutase 2, mitochondrial
chr24_-_32607801 1.17 ENSDART00000143781
eukaryotic translation initiation factor 1B
chr13_-_22831037 1.17 ENSDART00000057641
tetraspanin 15
chr4_+_1873500 1.17 ENSDART00000021139
FGFR1 oncogene partner 2
chr23_+_17596460 1.15 ENSDART00000002714
solute carrier family 17 (vesicular nucleotide transporter), member 9b
chr17_-_31195376 1.14 ENSDART00000086511
RNA pseudouridylate synthase domain containing 2
chr13_-_22831005 1.14 ENSDART00000143112
tetraspanin 15
chr8_-_47339136 1.14 ENSDART00000060853
peroxisomal biogenesis factor 10
chr23_+_28464194 1.13 ENSDART00000133736
ENSDARG00000093306
chr6_+_3556296 1.13 ENSDART00000041627
Sjogren syndrome antigen B (autoantigen La)
chr24_+_16575167 1.13

chr7_+_40878834 1.13

chr3_-_5157662 1.12 ENSDART00000169609
thyrotrophic embryonic factor b
chr20_+_34598242 1.11 ENSDART00000143765
golgin, rab6-interacting
chr24_-_1014256 1.11 ENSDART00000114544
cyclin-dependent kinase 13
chr24_-_1014491 1.11 ENSDART00000114544
cyclin-dependent kinase 13
chr6_+_52302917 1.10

chr5_-_34856057 1.10 ENSDART00000051312
tetratricopeptide repeat domain 33
chr5_+_19363942 1.10 ENSDART00000051614
trichoplein, keratin filament binding
chr11_-_7786415 1.09 ENSDART00000154569
ENSDARG00000097035
chr13_-_24265471 1.09 ENSDART00000016211
TATA box binding protein
chr14_-_5100304 1.09 ENSDART00000168074
polycomb group ring finger 1
chr8_-_49227143 1.07

chr21_+_20350218 1.07 ENSDART00000144366
si:dkey-30k6.5
chr24_-_1014640 1.06 ENSDART00000114544
cyclin-dependent kinase 13
chr6_+_49772891 1.06 ENSDART00000134207
cathepsin Z
chr5_+_19429500 1.05 ENSDART00000168868
ankyrin repeat domain 13A
chr15_-_35020312 1.05 ENSDART00000154094
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase a
chr13_-_44694139 1.04 ENSDART00000137275
si:dkeyp-2e4.6
chr3_-_34208507 1.04 ENSDART00000151634
trinucleotide repeat containing 6C1
chr17_-_9806413 1.03 ENSDART00000021942
e2f-associated phosphoprotein
chr15_+_21776031 1.03 ENSDART00000136151
zgc:162339
chr17_-_20198477 1.02 ENSDART00000063523
O-6-methylguanine-DNA methyltransferase
chr14_-_27040866 1.02 ENSDART00000173053
ENSDARG00000105327
chr3_-_26935578 1.02 ENSDART00000156311
activating transcription factor 7 interacting protein 2
chr25_-_24150237 1.02 ENSDART00000073527
SPT2 chromatin protein domain containing 1
chr10_-_180681 1.01

chr6_-_10492276 1.00 ENSDART00000002247
Sp3b transcription factor
chr20_+_46668743 0.99 ENSDART00000139051
ENSDART00000161320
basic leucine zipper transcription factor, ATF-like
chr5_+_71100066 0.99 ENSDART00000115182
nucleoporin 214
chr19_-_15324823 0.99 ENSDART00000169883
phosphatase and actin regulator 4a
chr5_-_56810425 0.98 ENSDART00000147875
ENSDART00000142776
ENSDARG00000095415
chr6_-_44164161 0.98 ENSDART00000035513
SHQ1, H/ACA ribonucleoprotein assembly factor
chr5_+_51186666 0.97 ENSDART00000165276
PAP associated domain containing 4
chr13_+_34563757 0.97 ENSDART00000133661
taspase, threonine aspartase, 1
chr25_-_4407821 0.97

chr9_-_32994156 0.97 ENSDART00000133382
zgc:112056
chr5_-_9443859 0.97

chr3_+_27582359 0.97 ENSDART00000019004
Rho GDP dissociation inhibitor (GDI) gamma
chr7_-_6618225 0.96 ENSDART00000113658
ENSDARG00000045199
chr10_+_30640 0.94 ENSDART00000040240
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr19_+_30835769 0.94 ENSDART00000023074
mitochondrial ribosomal protein S18B
chr21_+_6008781 0.94 ENSDART00000141607
folylpolyglutamate synthase
chr13_+_11307037 0.94 ENSDART00000138312
zinc finger and BTB domain containing 18
chr4_+_20901498 0.93

chr16_+_29756032 0.92 ENSDART00000103054
LysM, putative peptidoglycan-binding, domain containing 1
chr3_+_19515578 0.92 ENSDART00000007857
methyltransferase like 2A
chr15_+_46093261 0.92

chr10_-_36149719 0.92

chr21_-_43671213 0.90 ENSDART00000139008
si:dkey-229d11.3
chr5_-_56953716 0.90 ENSDART00000167892
zgc:193711
chr14_-_21779536 0.90

chr16_-_25318334 0.90 ENSDART00000058943
ENSDARG00000040280
chr6_+_48188313 0.89

chr1_-_40671522 0.89 ENSDART00000074777
ENSDART00000158114
huntingtin
chr10_-_7677571 0.89 ENSDART00000166234
UBX domain protein 8
chr7_+_38257950 0.88 ENSDART00000109495
ENSDART00000173804
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr11_+_7173167 0.88 ENSDART00000125619
thimet oligopeptidase 1
chr16_-_13723778 0.88 ENSDART00000139102
D site albumin promoter binding protein b
chr7_+_17460777 0.88

chr15_-_35020250 0.88 ENSDART00000154094
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase a
chr23_+_28464298 0.87 ENSDART00000133736
ENSDARG00000093306
chr7_-_5253629 0.87 ENSDART00000033316
VANGL planar cell polarity protein 2
chr19_-_12158958 0.87 ENSDART00000024193
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr13_-_43503453 0.87 ENSDART00000127930
ENSDART00000084474
family with sequence similarity 160, member B1
chr13_-_42598533 0.87 ENSDART00000160472
calpain 1, (mu/I) large subunit a
chr2_-_32278726 0.87 ENSDART00000159843
ENSDART00000056621
ENSDART00000039717
ENSDART00000145704
family with sequence similarity 49, member Ba
chr16_-_25317921 0.86

chr6_+_48188448 0.86

chr21_+_19040595 0.86 ENSDART00000145969
ENSDARG00000092282
chr6_+_23218068 0.86 ENSDART00000164960
syntaxin 8
chr19_+_1148544 0.85 ENSDART00000166088
zgc:63863
chr7_-_66470118 0.85 ENSDART00000021317
CTR9 homolog, Paf1/RNA polymerase II complex component
chr8_+_50162137 0.85 ENSDART00000056074
ectonucleoside triphosphate diphosphohydrolase 4
chr5_-_12242927 0.84 ENSDART00000137705
leucine-zipper-like transcription regulator 1
chr23_+_25953162 0.84 ENSDART00000138731
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr3_-_58400345 0.84 ENSDART00000052179
cerebellar degeneration-related protein 2a
chr19_+_37548595 0.84 ENSDART00000103159
small integral membrane protein 12
chr14_-_38606412 0.84 ENSDART00000139293
galactosidase, alpha
chr23_+_16880876 0.84 ENSDART00000141966
zgc:114081
chr16_-_25318260 0.83 ENSDART00000058943
ENSDARG00000040280
chr8_+_39726564 0.83 ENSDART00000145112
cytochrome c oxidase subunit VIa polypeptide 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:1990511 piRNA biosynthetic process(GO:1990511)
1.0 3.1 GO:0072045 convergent extension involved in nephron morphogenesis(GO:0072045)
1.0 2.9 GO:0021990 neural plate formation(GO:0021990) brain-derived neurotrophic factor receptor signaling pathway(GO:0031547) regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548) positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550) anterior neural plate formation(GO:0090017)
0.8 5.9 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479) negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.8 2.3 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.6 0.6 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.5 4.2 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.5 1.5 GO:0000493 box H/ACA snoRNP assembly(GO:0000493)
0.5 1.4 GO:0015846 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.5 1.8 GO:0018377 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.4 2.0 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.4 1.2 GO:0001780 neutrophil homeostasis(GO:0001780)
0.4 1.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.4 1.4 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.4 1.8 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.3 2.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.3 1.4 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.3 1.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.3 1.0 GO:0043368 T-helper cell lineage commitment(GO:0002295) T cell lineage commitment(GO:0002360) alpha-beta T cell lineage commitment(GO:0002363) type 2 immune response(GO:0042092) positive T cell selection(GO:0043368) CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) T cell selection(GO:0045058) T-helper 2 cell differentiation(GO:0045064) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540)
0.3 1.2 GO:0046326 positive regulation of glucose import(GO:0046326)
0.3 0.9 GO:0097435 fibril organization(GO:0097435)
0.3 0.8 GO:0009193 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.3 0.8 GO:0045813 positive regulation of Wnt signaling pathway, calcium modulating pathway(GO:0045813)
0.3 0.8 GO:0044375 regulation of peroxisome size(GO:0044375)
0.2 5.1 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.2 0.7 GO:0046485 ether lipid metabolic process(GO:0046485)
0.2 1.8 GO:0032447 protein urmylation(GO:0032447)
0.2 0.6 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.2 0.4 GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043370) regulation of alpha-beta T cell differentiation(GO:0046637) regulation of CD4-positive, alpha-beta T cell activation(GO:2000514)
0.2 3.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2 2.6 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.2 1.4 GO:0061316 canonical Wnt signaling pathway involved in heart development(GO:0061316)
0.2 2.4 GO:0017121 phospholipid scrambling(GO:0017121)
0.2 1.9 GO:0006465 signal peptide processing(GO:0006465)
0.2 2.0 GO:0008298 intracellular mRNA localization(GO:0008298)
0.2 0.8 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.2 0.9 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.1 2.8 GO:0034112 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.1 0.6 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 1.0 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.7 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.1 0.5 GO:1903059 regulation of lipoprotein metabolic process(GO:0050746) regulation of protein lipidation(GO:1903059)
0.1 0.6 GO:0032367 intracellular cholesterol transport(GO:0032367) positive regulation of lipid transport(GO:0032370)
0.1 0.5 GO:0072422 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.1 1.4 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.6 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 2.6 GO:0007338 single fertilization(GO:0007338)
0.1 0.5 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.1 0.6 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.5 GO:0033572 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.1 0.8 GO:0001845 phagolysosome assembly(GO:0001845)
0.1 0.6 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.1 0.5 GO:0034367 macromolecular complex remodeling(GO:0034367)
0.1 4.0 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.1 0.4 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 2.2 GO:0007568 aging(GO:0007568)
0.1 1.3 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.1 3.3 GO:0035825 reciprocal DNA recombination(GO:0035825)
0.1 0.8 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 0.5 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.5 GO:0008210 estrogen biosynthetic process(GO:0006703) estrogen metabolic process(GO:0008210)
0.1 0.8 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.4 GO:1900544 positive regulation of nucleotide metabolic process(GO:0045981) positive regulation of purine nucleotide metabolic process(GO:1900544)
0.1 0.3 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 0.6 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.1 2.6 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.1 1.1 GO:0046660 female sex differentiation(GO:0046660)
0.1 0.8 GO:0015701 bicarbonate transport(GO:0015701)
0.1 1.3 GO:0030593 neutrophil chemotaxis(GO:0030593)
0.1 0.6 GO:0045880 heart valve formation(GO:0003188) atrioventricular valve formation(GO:0003190) positive regulation of smoothened signaling pathway(GO:0045880)
0.1 1.0 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 1.2 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1 1.3 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1 0.3 GO:1902224 cellular ketone body metabolic process(GO:0046950) ketone body metabolic process(GO:1902224)
0.1 0.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 5.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 0.2 GO:0051645 Golgi localization(GO:0051645)
0.1 0.7 GO:0043584 nose development(GO:0043584)
0.1 1.7 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 4.2 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.1 0.9 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.6 GO:0021634 optic nerve formation(GO:0021634)
0.1 0.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 0.8 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.2 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.1 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0006544 glycine metabolic process(GO:0006544) glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.6 GO:0031577 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 0.7 GO:0009409 response to cold(GO:0009409)
0.0 0.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.6 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.9 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.9 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.6 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 1.0 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 1.2 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.2 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 5.4 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.6 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 1.0 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.6 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0 3.1 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.1 GO:0071236 response to antibiotic(GO:0046677) cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.0 0.9 GO:0032543 mitochondrial translation(GO:0032543)
0.0 1.7 GO:0048232 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 0.7 GO:0048264 determination of ventral identity(GO:0048264)
0.0 1.1 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 1.9 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 1.6 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:0043486 histone exchange(GO:0043486)
0.0 0.1 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 0.2 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 2.5 GO:0051604 protein maturation(GO:0051604)
0.0 1.3 GO:0051225 spindle assembly(GO:0051225)
0.0 0.3 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.0 GO:0051126 negative regulation of actin nucleation(GO:0051126)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0043102 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.9 GO:0019953 sexual reproduction(GO:0019953)
0.0 0.1 GO:0006739 NADP metabolic process(GO:0006739)
0.0 0.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.9 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.5 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.3 GO:0015804 neutral amino acid transport(GO:0015804) glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.6 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.4 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.3 GO:0071482 cellular response to light stimulus(GO:0071482)
0.0 0.3 GO:0010469 regulation of receptor activity(GO:0010469)
0.0 0.3 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 1.1 GO:0007219 Notch signaling pathway(GO:0007219)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0043291 RAVE complex(GO:0043291)
0.4 4.6 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.3 2.2 GO:0071546 pi-body(GO:0071546)
0.3 1.9 GO:0005787 signal peptidase complex(GO:0005787)
0.3 1.6 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.2 2.0 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.2 1.3 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.2 0.6 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 0.8 GO:0000811 GINS complex(GO:0000811)
0.2 0.8 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.2 0.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.6 GO:0070985 TFIIK complex(GO:0070985)
0.1 1.6 GO:0000813 ESCRT I complex(GO:0000813)
0.1 1.6 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.1 GO:0089701 U2AF(GO:0089701)
0.1 0.6 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 1.4 GO:0031209 SCAR complex(GO:0031209)
0.1 1.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 1.0 GO:0070652 HAUS complex(GO:0070652)
0.1 0.3 GO:0097361 CIA complex(GO:0097361)
0.1 1.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 3.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.2 GO:0070390 transcription export complex 2(GO:0070390)
0.1 0.2 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 1.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.3 GO:0031251 PAN complex(GO:0031251)
0.1 4.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 0.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.2 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.1 0.8 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 1.1 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.6 GO:0043209 myelin sheath(GO:0043209)
0.0 1.1 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.7 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 4.3 GO:0005770 late endosome(GO:0005770)
0.0 1.3 GO:0071565 nBAF complex(GO:0071565)
0.0 1.2 GO:0005902 microvillus(GO:0005902)
0.0 0.2 GO:0044439 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 1.4 GO:0005811 lipid particle(GO:0005811)
0.0 0.7 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.2 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.9 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.6 GO:0015030 Cajal body(GO:0015030)
0.0 1.3 GO:0016605 PML body(GO:0016605)
0.0 1.8 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.7 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.2 GO:0000938 GARP complex(GO:0000938)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.4 GO:0030027 lamellipodium(GO:0030027)
0.0 3.8 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 3.7 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.5 GO:0097346 INO80-type complex(GO:0097346)
0.0 0.2 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.0 0.1 GO:0031045 dense core granule(GO:0031045)
0.0 1.4 GO:0098800 inner mitochondrial membrane protein complex(GO:0098800)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.2 GO:0030663 COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663)
0.0 0.5 GO:0005643 nuclear pore(GO:0005643)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.9 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.7 2.0 GO:0047611 acetylspermidine deacetylase activity(GO:0047611)
0.6 2.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.5 2.2 GO:0034584 piRNA binding(GO:0034584)
0.5 3.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.5 1.4 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.5 1.9 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.5 1.8 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.4 4.6 GO:0030332 cyclin binding(GO:0030332)
0.4 1.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.4 3.3 GO:0035804 structural constituent of egg coat(GO:0035804)
0.3 1.4 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326)
0.3 1.9 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.3 0.6 GO:0001016 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 3 promoter sequence-specific DNA binding(GO:0001006) RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.3 3.1 GO:0070697 activin receptor binding(GO:0070697)
0.3 1.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.2 0.9 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2 1.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 0.9 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.2 1.4 GO:0051920 peroxiredoxin activity(GO:0051920)
0.2 1.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.2 0.9 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.2 1.9 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.2 0.6 GO:0008126 acetylesterase activity(GO:0008126)
0.2 0.8 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.2 0.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 0.5 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.2 2.1 GO:0003785 actin monomer binding(GO:0003785)
0.2 2.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 0.8 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.2 1.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.6 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.1 0.6 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.1 0.4 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.1 1.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 1.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.9 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.1 1.0 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 4.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 1.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 1.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.5 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 2.1 GO:0031386 protein tag(GO:0031386)
0.1 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.6 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 1.3 GO:2001069 glycogen binding(GO:2001069)
0.1 0.6 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 0.9 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.3 GO:0034417 bisphosphoglycerate 3-phosphatase activity(GO:0034417)
0.1 2.0 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.6 GO:0032183 SUMO binding(GO:0032183)
0.1 0.8 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 0.6 GO:0005537 mannose binding(GO:0005537)
0.1 1.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.8 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 0.4 GO:0043531 ADP binding(GO:0043531)
0.1 1.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.7 GO:0051117 ATPase binding(GO:0051117)
0.1 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.7 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 1.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.7 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.8 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.5 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 0.7 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.2 GO:0043878 aminobutyraldehyde dehydrogenase activity(GO:0019145) glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.1 0.6 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.1 0.3 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 1.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 4.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0070008 serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
0.0 0.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.4 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 1.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 2.2 GO:0031625 ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.0 3.1 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 1.7 GO:0043130 ubiquitin-like protein binding(GO:0032182) ubiquitin binding(GO:0043130)
0.0 0.4 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.4 GO:0070035 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 6.2 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 1.3 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.2 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.9 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 2.9 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.1 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 0.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.5 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.6 GO:0004620 phospholipase activity(GO:0004620)
0.0 0.2 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 2.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0008483 transaminase activity(GO:0008483)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.2 0.6 PID BCR 5PATHWAY BCR signaling pathway
0.2 3.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 1.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 1.6 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 2.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 0.9 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 0.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 0.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 0.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 1.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 0.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 0.9 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.5 PID IL1 PATHWAY IL1-mediated signaling events
0.0 2.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 4.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.3 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.3 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.7 PID MYC PATHWAY C-MYC pathway
0.0 0.4 PID FOXO PATHWAY FoxO family signaling
0.0 0.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 0.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 3.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 1.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 0.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 2.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 0.9 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 2.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 1.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 1.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 0.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 0.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 0.9 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.1 0.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.6 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 0.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 2.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 2.7 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.8 REACTOME RNA POL III TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.0 0.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides