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DANIO-CODE

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Results for elf3

Z-value: 1.15

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Transcription factors associated with elf3

Gene Symbol Gene ID Gene Info
elf3
ENSDARG00000077982 E74-like factor 3 (ets domain transcription factor, epithelial-specific )

Activity profile of elf3 motif

Sorted Z-values of elf3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of elf3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
KN150589v1_-_5209 3.04 ENSDART00000157761
ENSDART00000157531
elovl7b
ELOVL fatty acid elongase 7b
chr17_+_19606608 2.96 ENSDART00000044993
ENSDART00000131863
rgs7a
regulator of G protein signaling 7a
chr6_+_3556296 2.75 ENSDART00000041627
ssb
Sjogren syndrome antigen B (autoantigen La)
chr25_+_4888647 2.69 ENSDART00000165933
ENSDART00000159537
hdac10
histone deacetylase 10
chr11_-_41751151 2.67 ENSDART00000173086
zgc:175088
zgc:175088
chr23_+_32174669 2.36 ENSDART00000000992
ENSDARG00000000887
ENSDARG00000000887
chr22_-_17627900 2.34 ENSDART00000138483
si:ch73-243b8.4
si:ch73-243b8.4
chr19_-_20819477 2.15 ENSDART00000151356
dazl
deleted in azoospermia-like
chr13_-_37340209 2.11

chr18_+_27769446 1.99

chr6_-_10492276 1.95 ENSDART00000002247
sp3b
Sp3b transcription factor
chr22_-_17627831 1.94 ENSDART00000138483
si:ch73-243b8.4
si:ch73-243b8.4
chr19_-_35400339 1.85

chr10_-_180603 1.83

chr12_+_20505619 1.80 ENSDART00000074384
stx4
syntaxin 4
chr5_-_28931727 1.74 ENSDART00000174697
arrdc1a
arrestin domain containing 1a
chr17_-_44326992 1.70 ENSDART00000148786
exoc5
exocyst complex component 5
chr5_-_56641212 1.68 ENSDART00000050957
fer
fer (fps/fes related) tyrosine kinase
chr23_-_32267833 1.64

chr20_-_13729816 1.63 ENSDART00000078893
ezrb
ezrin b
chr21_+_6008781 1.59 ENSDART00000141607
fpgs
folylpolyglutamate synthase
chr14_-_21779536 1.57

chr19_+_43745546 1.55 ENSDART00000145846
sesn2
sestrin 2
chr23_+_32175042 1.54 ENSDART00000138849
ENSDARG00000000887
ENSDARG00000000887
chr16_-_15497269 1.51 ENSDART00000053754
has2
hyaluronan synthase 2
chr19_+_43745687 1.50 ENSDART00000102384
sesn2
sestrin 2
chr14_-_6901209 1.50 ENSDART00000167994
ENSDART00000166532
stox2b
storkhead box 2b
chr5_-_56641061 1.50 ENSDART00000050957
fer
fer (fps/fes related) tyrosine kinase
chr3_+_479366 1.48

chr25_-_19889225 1.44

chr13_-_35782121 1.43 ENSDART00000013961
mycla
MYCL proto-oncogene, bHLH transcription factor a
chr14_-_27040866 1.41 ENSDART00000173053
CU062454.1
ENSDARG00000105327
chr11_-_41751050 1.40 ENSDART00000173086
zgc:175088
zgc:175088
chr2_-_24413154 1.38 ENSDART00000145526
slc12a7a
solute carrier family 12 (potassium/chloride transporter), member 7a
chr5_-_23741221 1.37 ENSDART00000042481
phf23a
PHD finger protein 23a
chr20_-_34126039 1.36 ENSDART00000033817
scyl3
SCY1-like, kinase-like 3
chr8_+_3373066 1.34 ENSDART00000017850
ctu1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr17_+_44327269 1.32 ENSDART00000045882
ap5m1
adaptor-related protein complex 5, mu 1 subunit
chr6_-_44164161 1.30 ENSDART00000035513
shq1
SHQ1, H/ACA ribonucleoprotein assembly factor
chr15_-_38027363 1.29 ENSDART00000157550
si:dkey-238d18.15
si:dkey-238d18.15
chr10_-_25383262 1.28 ENSDART00000166348
cct8
chaperonin containing TCP1, subunit 8 (theta)
chr5_-_40524177 1.28 ENSDART00000083561
mtmr12
myotubularin related protein 12
chr5_-_56641001 1.26 ENSDART00000149855
fer
fer (fps/fes related) tyrosine kinase
chr20_-_18482817 1.26 ENSDART00000159636
vipas39
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
chr2_-_30216377 1.26 ENSDART00000130142
ube2w
ubiquitin-conjugating enzyme E2W (putative)
chr5_-_38570658 1.25 ENSDART00000020808
paqr3a
progestin and adipoQ receptor family member IIIa
chr3_+_48810347 1.25 ENSDART00000133283
prkcsh
protein kinase C substrate 80K-H
chr13_-_21541531 1.24 ENSDART00000067537
elovl6l
ELOVL family member 6, elongation of long chain fatty acids like
chr7_+_56076854 1.22

chr23_+_26099718 1.22 ENSDART00000141553
pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr14_+_31596468 1.21 ENSDART00000173259
BX005454.1
ENSDARG00000100646
chr6_-_10492123 1.21 ENSDART00000002247
sp3b
Sp3b transcription factor
chr16_-_29755471 1.20 ENSDART00000133965
scnm1
sodium channel modifier 1
chr4_-_17364090 1.20 ENSDART00000134467
parpbp
PARP1 binding protein
chr1_+_32825950 1.18 ENSDART00000018472
chmp2bb
charged multivesicular body protein 2Bb
chr10_-_180681 1.18

chr5_+_35186037 1.17 ENSDART00000127383
ENSDART00000022043
stard8
StAR-related lipid transfer (START) domain containing 8
chr19_+_4135556 1.16 ENSDART00000162461
btr26
bloodthirsty-related gene family, member 26
chr24_+_25995817 1.16 ENSDART00000139017
tmtopsb
teleost multiple tissue opsin b
chr5_-_56640932 1.15 ENSDART00000149855
fer
fer (fps/fes related) tyrosine kinase
chr20_-_33802082 1.13 ENSDART00000166573
rock2b
rho-associated, coiled-coil containing protein kinase 2b
chr5_-_38571198 1.12 ENSDART00000020808
paqr3a
progestin and adipoQ receptor family member IIIa
chr6_+_13766964 1.12 ENSDART00000136006
ENSDART00000009382
dnpep
aspartyl aminopeptidase
chr18_+_45669615 1.11 ENSDART00000150973
prrg4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr5_+_40235387 1.10 ENSDART00000147767
si:dkey-3h3.3
si:dkey-3h3.3
chr19_+_43745515 1.09 ENSDART00000145846
sesn2
sestrin 2
chr8_+_150970 1.08

chr10_-_44173041 1.06

chr4_-_7861030 1.06 ENSDART00000067339
mcm10
minichromosome maintenance 10 replication initiation factor
chr1_+_157840 1.05 ENSDART00000152205
ENSDART00000160843
cul4a
cullin 4A
chr4_+_17653548 1.02 ENSDART00000026509
cwf19l1
CWF19-like 1, cell cycle control
chr16_+_38251653 1.01 ENSDART00000044971
myo1eb
myosin IE, b
chr16_+_38188364 0.98 ENSDART00000131694
selenbp1
selenium binding protein 1
chr4_-_12979905 0.97 ENSDART00000150674
tmbim4
transmembrane BAX inhibitor motif containing 4
chr15_-_5810906 0.97 ENSDART00000142334
hnrnpl2
heterogeneous nuclear ribonucleoprotein L2
chr22_-_16351654 0.96 ENSDART00000168170
ttc39c
tetratricopeptide repeat domain 39C
chr20_-_22899048 0.96 ENSDART00000063609
fip1l1a
FIP1 like 1a (S. cerevisiae)
chr2_-_30216333 0.96 ENSDART00000130142
ube2w
ubiquitin-conjugating enzyme E2W (putative)
KN149781v1_+_5174 0.96 ENSDART00000165339
CDC37
cell division cycle 37
chr8_+_3372903 0.95 ENSDART00000017850
ctu1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr16_-_41718971 0.94

chr12_-_26445609 0.94 ENSDART00000132737
ENSDART00000163931
acsf2
acyl-CoA synthetase family member 2
chr8_+_50754290 0.93 ENSDART00000155664
si:ch73-6l19.2
si:ch73-6l19.2
chr17_+_24045582 0.93 ENSDART00000132755
b3gnt2b
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2b
chr16_+_29574449 0.92 ENSDART00000148450
ctss2.1
cathepsin S, ortholog2, tandem duplicate 1
chr24_+_16575167 0.91

chr19_-_24541229 0.90 ENSDART00000080632
zgc:64022
zgc:64022
chr5_-_45986774 0.90

chr4_-_12979951 0.90 ENSDART00000013839
tmbim4
transmembrane BAX inhibitor motif containing 4
chr10_-_20524937 0.90

chr24_-_13205000 0.90 ENSDART00000134482
terf1
telomeric repeat binding factor (NIMA-interacting) 1
chr2_-_27996140 0.89 ENSDART00000097868
tgs1
trimethylguanosine synthase 1
chr20_+_2100836 0.89

chr13_-_33348231 0.89 ENSDART00000160520
mad2l1bp
MAD2L1 binding protein
chr8_-_47339136 0.87 ENSDART00000060853
pex10
peroxisomal biogenesis factor 10
chr12_+_30590876 0.86 ENSDART00000066259
kcnk1a
potassium channel, subfamily K, member 1a
chr14_+_21779325 0.85 ENSDART00000106147
slc43a1a
solute carrier family 43 (amino acid system L transporter), member 1a
chr15_-_35242832 0.84 ENSDART00000099677
bloc1s3
biogenesis of lysosomal organelles complex-1, subunit 3
chr20_-_39599959 0.83

chr15_+_14918610 0.83 ENSDART00000163066
diabloa
diablo, IAP-binding mitochondrial protein a
chr20_+_27188382 0.83 ENSDART00000062094
tmem251
transmembrane protein 251
chr23_-_42918086 0.83 ENSDART00000102328
pfkfb2a
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr15_+_1569674 0.83 ENSDART00000130413
smc4
structural maintenance of chromosomes 4
chr21_+_6091802 0.83 ENSDART00000147716
si:dkey-93m18.3
si:dkey-93m18.3
chr6_-_44163685 0.83 ENSDART00000035513
shq1
SHQ1, H/ACA ribonucleoprotein assembly factor
chr5_+_26925663 0.82 ENSDART00000051491
sfrp1a
secreted frizzled-related protein 1a
chr21_+_19040595 0.82 ENSDART00000145969
BX000991.1
ENSDARG00000092282
chr18_+_20045544 0.80

chr25_-_34596585 0.80 ENSDART00000171659
zgc:162611
zgc:162611
chr14_+_25927045 0.79 ENSDART00000168673
ENSDART00000128971
gm2a
GM2 ganglioside activator
chr6_-_10492724 0.79 ENSDART00000002247
sp3b
Sp3b transcription factor
chr25_-_21409895 0.78 ENSDART00000010706
immp2l
inner mitochondrial membrane peptidase subunit 2
chr22_+_23260413 0.78

chr16_+_29756032 0.78 ENSDART00000103054
lysmd1
LysM, putative peptidoglycan-binding, domain containing 1
chr13_-_35781541 0.78 ENSDART00000147522
mycla
MYCL proto-oncogene, bHLH transcription factor a
chr6_+_3313468 0.77 ENSDART00000011785
rad54l
RAD54-like (S. cerevisiae)
chr16_+_54861268 0.77

chr17_-_45549323 0.76

chr20_+_49380442 0.76

chr17_+_24045786 0.76 ENSDART00000132755
b3gnt2b
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2b
chr23_-_42918055 0.76 ENSDART00000102328
pfkfb2a
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr16_+_38251717 0.75 ENSDART00000044971
myo1eb
myosin IE, b
chr19_+_47918720 0.75 ENSDART00000157886
zgc:114119
zgc:114119
chr5_-_23741624 0.75 ENSDART00000042481
phf23a
PHD finger protein 23a
chr20_+_26005068 0.75 ENSDART00000016864
slc35f6
solute carrier family 35, member F6
chr14_-_30564987 0.74 ENSDART00000173451
si:ch211-126c2.4
si:ch211-126c2.4
chr20_+_13245355 0.74 ENSDART00000034098
dtl
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr19_+_1148544 0.74 ENSDART00000166088
zgc:63863
zgc:63863
chr2_+_36738864 0.72 ENSDART00000019063
pdcd10b
programmed cell death 10b
chr5_-_25133229 0.71 ENSDART00000051566
zgc:101016
zgc:101016
chr4_-_20092577 0.71 ENSDART00000164410
dennd6b
DENN/MADD domain containing 6B
chr19_-_40111964 0.70

chr2_+_5494310 0.70 ENSDART00000154167
sft2d3
SFT2 domain containing 3
chr18_+_20045293 0.69 ENSDART00000139441
morf4l1
mortality factor 4 like 1
chr19_-_15324823 0.69 ENSDART00000169883
phactr4a
phosphatase and actin regulator 4a
chr1_-_21188809 0.69 ENSDART00000169381
melk
maternal embryonic leucine zipper kinase
chr10_-_36848872 0.68

chr3_+_19829535 0.68

chr8_-_11164610 0.67 ENSDART00000147817
fam208b
family with sequence similarity 208, member B
chr7_-_56465369 0.66 ENSDART00000020967
csnk2a2a
casein kinase 2, alpha prime polypeptide a
chr5_-_37359835 0.66 ENSDART00000141059
mpzl2b
myelin protein zero-like 2b
chr3_-_34208507 0.66 ENSDART00000151634
tnrc6c1
trinucleotide repeat containing 6C1
chr19_+_1356915 0.66 ENSDART00000081779
zdhhc3b
zinc finger, DHHC-type containing 3b
chr8_+_8908955 0.65 ENSDART00000131215
slc35a2
solute carrier family 35 (UDP-galactose transporter), member 2
chr14_+_43357313 0.65

chr18_-_40763266 0.65 ENSDART00000130397
akt2
v-akt murine thymoma viral oncogene homolog 2
chr15_+_21776031 0.64 ENSDART00000136151
NKAPD1
zgc:162339
chr22_-_17529086 0.64

chr3_-_37429712 0.64 ENSDART00000161401
arf2a
ADP-ribosylation factor 2a
chr20_+_24047842 0.63 ENSDART00000128616
ENSDART00000144195
casp8ap2
caspase 8 associated protein 2
chr5_+_26925957 0.63

chr14_+_45774485 0.63 ENSDART00000146918
rnf44
ring finger protein 44
chr8_+_3373146 0.63 ENSDART00000017850
ctu1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr16_+_25256694 0.62 ENSDART00000156416
wu:fe05a04
wu:fe05a04
chr7_-_40307611 0.62 ENSDART00000173926
ENSDART00000010035
dnajb6b
DnaJ (Hsp40) homolog, subfamily B, member 6b
chr12_-_26445560 0.62 ENSDART00000138437
acsf2
acyl-CoA synthetase family member 2
chr22_+_1153361 0.62 ENSDART00000159761
irf6
interferon regulatory factor 6
chr3_+_19095975 0.62 ENSDART00000134514
smarca4a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a
chr17_-_45549413 0.61

chr5_-_23741680 0.61 ENSDART00000042481
phf23a
PHD finger protein 23a
chr23_-_42918166 0.60 ENSDART00000102328
pfkfb2a
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr24_-_1160886 0.60

chr8_-_11164322 0.60 ENSDART00000147817
fam208b
family with sequence similarity 208, member B
chr12_+_28795843 0.59 ENSDART00000076342
rnf40
ring finger protein 40
chr25_+_35159606 0.59

chr3_+_25726394 0.59 ENSDART00000097679
zgc:171844
zgc:171844
chr2_+_31855153 0.59 ENSDART00000066789
stard3nl
STARD3 N-terminal like
chr13_+_34563757 0.59 ENSDART00000133661
tasp1
taspase, threonine aspartase, 1
chr16_+_54953101 0.59

chr16_-_6909034 0.59 ENSDART00000149206
ENSDART00000149778
mbpb
myelin basic protein b
chr8_-_31407839 0.58 ENSDART00000098912
znf131
zinc finger protein 131
chr8_-_11164125 0.58 ENSDART00000147817
fam208b
family with sequence similarity 208, member B
chr18_+_20044862 0.58 ENSDART00000139441
morf4l1
mortality factor 4 like 1
chr15_-_778461 0.58 ENSDART00000153874
si:dkey-7i4.19
si:dkey-7i4.19
chr9_-_46609555 0.58

chr20_-_16271738 0.57 ENSDART00000012476
coa7
cytochrome c oxidase assembly factor 7
chr24_-_37178907 0.57

chr2_-_30216240 0.57 ENSDART00000130142
ube2w
ubiquitin-conjugating enzyme E2W (putative)
chr18_-_40763107 0.57 ENSDART00000130397
akt2
v-akt murine thymoma viral oncogene homolog 2
chr2_-_9898351 0.56 ENSDART00000165712
selt1a
selenoprotein T, 1a
chr15_+_38113014 0.56

chr5_-_23741334 0.55 ENSDART00000042481
phf23a
PHD finger protein 23a
chr12_-_33457780 0.55 ENSDART00000161167
mbtd1
mbt domain containing 1
chr2_-_37479961 0.55 ENSDART00000145896
si:dkey-57k2.7
si:dkey-57k2.7
chr6_+_10098305 0.55 ENSDART00000151477
cobll1a
cordon-bleu WH2 repeat protein-like 1a
chr2_+_29468496 0.55

chr2_-_30216703 0.55 ENSDART00000130142
ube2w
ubiquitin-conjugating enzyme E2W (putative)
chr14_+_32511519 0.54 ENSDART00000166351
nkrf
NFKB repressing factor
chr11_-_7786415 0.54 ENSDART00000154569
CR450813.1
ENSDARG00000097035
chr17_-_24872401 0.54 ENSDART00000135569
gale
UDP-galactose-4-epimerase
chr15_-_5811394 0.53 ENSDART00000158522
hnrnpl2
heterogeneous nuclear ribonucleoprotein L2
chr19_+_43277870 0.53 ENSDART00000135164
pdcd6ip
programmed cell death 6 interacting protein
chr7_+_26378093 0.53 ENSDART00000173823
ENSDART00000101053
tp53i11a
tumor protein p53 inducible protein 11a
chr6_-_14938420 0.52 ENSDART00000087797
tgfbrap1
transforming growth factor, beta receptor associated protein 1
chr14_-_32467378 0.52

chr16_+_43464824 0.52 ENSDART00000032778
rnf144b
ring finger protein 144B
chr12_-_28840748 0.52

chr21_-_44748449 0.51 ENSDART00000026178
kif4
kinesin family member 4
chr15_-_8880237 0.50 ENSDART00000008273
rab4b
RAB4B, member RAS oncogene family
chr25_+_35159867 0.50

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 5.8 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.7 2.1 GO:0000493 box H/ACA snoRNP assembly(GO:0000493)
0.6 1.9 GO:0003091 renal water homeostasis(GO:0003091) renal water transport(GO:0003097) extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.5 3.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.5 4.1 GO:1901031 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.4 2.1 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.4 2.9 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.4 1.6 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.4 1.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.3 1.3 GO:0035095 behavioral response to nicotine(GO:0035095)
0.3 1.1 GO:0046326 positive regulation of glucose import(GO:0046326)
0.2 3.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 1.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.2 0.6 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 0.8 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.2 0.7 GO:0072401 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.2 4.4 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.5 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.1 1.7 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.3 GO:0043393 regulation of protein binding(GO:0043393)
0.1 1.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.8 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 1.0 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.7 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 3.9 GO:0035825 reciprocal DNA recombination(GO:0035825)
0.1 1.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 1.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 2.1 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 1.8 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 1.0 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 1.8 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1 0.4 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.1 0.4 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 0.5 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 1.3 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 0.6 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.1 0.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.7 GO:0032387 negative regulation of intracellular transport(GO:0032387)
0.1 1.7 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.1 0.4 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.1 0.9 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 1.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 0.9 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 0.2 GO:0042665 ectodermal cell fate commitment(GO:0001712) ectodermal cell fate specification(GO:0001715) ectodermal cell differentiation(GO:0010668) regulation of ectodermal cell fate specification(GO:0042665) regulation of ectoderm development(GO:2000383)
0.1 0.3 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.1 1.6 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.1 0.2 GO:0044209 AMP salvage(GO:0044209)
0.0 4.3 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.7 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.6 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.3 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.9 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.3 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.0 0.8 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.2 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 1.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.5 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.8 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.2 GO:0031053 primary miRNA processing(GO:0031053)
0.0 1.2 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.7 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:2000480 regulation of cAMP-dependent protein kinase activity(GO:2000479) negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048) amino sugar biosynthetic process(GO:0046349)
0.0 0.2 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 1.2 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.9 GO:0071600 otic vesicle morphogenesis(GO:0071600)
0.0 0.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.2 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 1.4 GO:0007283 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 0.1 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.7 GO:0061351 neural precursor cell proliferation(GO:0061351)
0.0 0.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0060847 endothelial cell fate specification(GO:0060847) blood vessel endothelial cell fate specification(GO:0097101)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.4 GO:0048278 membrane docking(GO:0022406) vesicle docking(GO:0048278)
0.0 0.1 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0002144 cytosolic tRNA wobble base thiouridylase complex(GO:0002144)
0.5 4.1 GO:0061700 GATOR2 complex(GO:0061700)
0.4 1.2 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.4 1.1 GO:0031298 replication fork protection complex(GO:0031298)
0.3 1.2 GO:0017177 glucosidase II complex(GO:0017177)
0.2 0.7 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 1.8 GO:0016580 Sin3 complex(GO:0016580)
0.2 1.8 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 1.6 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.3 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.1 1.7 GO:0000145 exocyst(GO:0000145)
0.1 0.3 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
0.1 1.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.3 GO:0070390 transcription export complex 2(GO:0070390)
0.1 0.2 GO:0097361 CIA complex(GO:0097361)
0.1 0.9 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 1.0 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.9 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.1 5.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 1.0 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.8 GO:0005902 microvillus(GO:0005902)
0.1 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.6 GO:0043209 myelin sheath(GO:0043209)
0.0 3.1 GO:0055037 recycling endosome(GO:0055037)
0.0 0.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 2.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.8 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.7 GO:0016528 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)
0.0 0.5 GO:0030286 dynein complex(GO:0030286)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 0.6 GO:0016605 PML body(GO:0016605)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.0 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.4 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.7 GO:0030027 lamellipodium(GO:0030027)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0047611 acetylspermidine deacetylase activity(GO:0047611)
0.6 1.9 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.5 4.1 GO:0070728 leucine binding(GO:0070728)
0.4 5.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.4 2.0 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.4 1.6 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326)
0.3 0.9 GO:0071532 ankyrin repeat binding(GO:0071532)
0.3 3.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.2 4.4 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 1.8 GO:0008494 translation activator activity(GO:0008494)
0.1 1.3 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 1.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.8 GO:0015616 DNA translocase activity(GO:0015616)
0.1 1.4 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 1.7 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 1.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 1.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.0 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 2.0 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.1 0.5 GO:0051920 peroxiredoxin activity(GO:0051920)
0.1 2.9 GO:0000049 tRNA binding(GO:0000049)
0.1 0.2 GO:0004001 adenosine kinase activity(GO:0004001)
0.1 0.7 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 2.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 3.4 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.7 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.7 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.9 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 5.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.8 GO:0008047 enzyme activator activity(GO:0008047)
0.0 0.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.3 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.0 0.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.0 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.5 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.3 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 2.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 3.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 0.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.0 PID AURORA B PATHWAY Aurora B signaling
0.0 0.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.3 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.2 2.2 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.2 1.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 1.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 2.7 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 5.1 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.1 0.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 3.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.2 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 1.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 3.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 1.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases