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Results for emx2+emx3

Z-value: 1.67

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Transcription factors associated with emx2+emx3

Gene Symbol Gene ID Gene Info
ENSDARG00000020417 empty spiracles homeobox 3
ENSDARG00000039701 empty spiracles homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
emx2dr10_dc_chr13_+_19191645_19191712-0.731.4e-03Click!
emx3dr10_dc_chr14_-_26078923_26078978-0.611.2e-02Click!

Activity profile of emx2+emx3 motif

Sorted Z-values of emx2+emx3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of emx2+emx3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_-_10411573 6.92 ENSDART00000171232
coiled-coil domain containing 106b
chr11_-_6442588 6.34 ENSDART00000137879
zgc:162969
chr8_-_23759076 5.05 ENSDART00000145894
zgc:195245
chr1_-_18118467 4.61 ENSDART00000142026
si:dkey-167i21.2
chr19_-_20819477 4.58 ENSDART00000151356
deleted in azoospermia-like
chr19_-_20819101 4.40 ENSDART00000137590
deleted in azoospermia-like
chr13_+_29904945 4.15 ENSDART00000057525
DnaJ (Hsp40) homolog, subfamily B, member 12a
chr18_-_40718244 3.96 ENSDART00000077577
si:ch211-132b12.8
chr21_+_6289363 3.90 ENSDART00000138600
si:ch211-225g23.1
chr22_+_17235696 3.57 ENSDART00000134798
tudor domain containing 5
chr2_+_15432208 3.56 ENSDART00000027171
coagulation factor IIIb
chr19_-_1571878 3.53

chr19_-_10411518 3.52 ENSDART00000171232
coiled-coil domain containing 106b
chr7_-_73016194 3.42

chr2_+_15432130 3.34 ENSDART00000027171
coagulation factor IIIb
chr4_+_9466175 3.17 ENSDART00000012659
zgc:55888
chr21_+_22598805 3.03 ENSDART00000142495
ENSDARG00000089088
chr5_+_37303599 3.03 ENSDART00000097754
ENSDART00000162470
transmembrane protease, serine 4b
chr3_+_32285237 2.85 ENSDART00000157324
proline rich Gla (G-carboxyglutamic acid) 2
chr5_+_58936399 2.73

chr19_-_18664720 2.72 ENSDART00000108627
sorting nexin 10a
chr15_+_35076414 2.68 ENSDART00000165210
zgc:66024
chr10_-_44713495 2.64 ENSDART00000076084
nucleophosmin/nucleoplasmin, 2b
chr21_-_32027717 2.62 ENSDART00000131651
ENSDARG00000073961
chr3_+_12087549 2.60

chr23_+_12225922 2.49 ENSDART00000136046
protein phosphatase 1, regulatory subunit 3Da
chr18_-_38787413 2.48

chr13_+_849563 2.40

chr21_+_31216418 2.39 ENSDART00000178521
argininosuccinate lyase
chr4_-_3340315 2.38 ENSDART00000009076
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr24_+_41991604 2.23

chr17_-_1907622 2.21 ENSDART00000156489
x globin
chr1_+_18118735 2.20 ENSDART00000078610
solute carrier family 25, member 51a
chr19_-_10411878 2.12 ENSDART00000136653
coiled-coil domain containing 106b
chr19_-_25565317 2.11 ENSDART00000175266
protein tyrosine phosphatase type IVA, member 3
chr7_-_73613531 2.10 ENSDART00000128137
zgc:92594
chr7_+_66660882 2.07 ENSDART00000082664
SET binding factor 2
chr21_+_13291305 2.04 ENSDART00000134347
zgc:113162
chr21_-_44086464 2.03 ENSDART00000130833
ENSDARG00000087492
chr7_-_26226924 2.01 ENSDART00000058910
SRY (sex determining region Y)-box 19b
chr11_-_44756789 1.96 ENSDART00000161712
synaptogyrin 2b
chr22_+_2735606 1.90 ENSDART00000133652
si:dkey-20i20.11
chr14_-_6738260 1.89 ENSDART00000171792
RUN and FYVE domain containing 1
chr14_-_26127173 1.87 ENSDART00000088690
lectin, mannose-binding 2
chr11_+_17849608 1.83 ENSDART00000020283
RNA pseudouridylate synthase domain containing 4
chr13_-_51743281 1.82

KN149710v1_+_38638 1.79

chr3_+_40022244 1.78 ENSDART00000102526
growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)
chr21_-_45323151 1.77 ENSDART00000151106
ENSDARG00000053404
chr25_-_20933295 1.77 ENSDART00000138985
ENSDART00000046298
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr21_-_2159827 1.76 ENSDART00000169897
zgc:171220
chr4_+_9466147 1.75 ENSDART00000012659
zgc:55888
chr3_+_33608070 1.75

chr1_+_8468971 1.74 ENSDART00000081343
polo-like kinase 1 (Drosophila)
chr15_+_35089305 1.74 ENSDART00000156515
zgc:55621
chr12_+_20222000 1.72 ENSDART00000150020
hemoglobin, alpha embryonic 5
chr21_-_2159785 1.72 ENSDART00000169897
zgc:171220
chr19_-_25564720 1.71 ENSDART00000148432
protein tyrosine phosphatase type IVA, member 3
chr17_-_1907667 1.71 ENSDART00000156489
x globin
chr21_+_13291242 1.71 ENSDART00000134347
zgc:113162
chr13_+_30441704 1.70 ENSDART00000010052
peptidylprolyl isomerase Fa
chr11_-_6442490 1.69 ENSDART00000137879
zgc:162969
chr10_+_27028355 1.66 ENSDART00000064111
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed b
chr10_+_45108698 1.65

chr2_+_1645259 1.65 ENSDART00000155956
synovial sarcoma, X breakpoint 2 interacting protein a
chr15_-_44581550 1.57

chr13_-_14950971 1.56 ENSDART00000157482
sideroflexin 5a
chr19_-_5186692 1.55 ENSDART00000037007
triosephosphate isomerase 1a
chr2_-_17721810 1.52 ENSDART00000100201
ENSDART00000141188
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr19_-_20819057 1.51 ENSDART00000136826
deleted in azoospermia-like
chr5_+_6391432 1.51 ENSDART00000170564
ENSDART00000086666
sperm-tail PG-rich repeat containing 2
chr21_+_13291347 1.48 ENSDART00000134347
zgc:113162
chr20_-_22532817 1.48 ENSDART00000177772
ENSDARG00000108228
chr18_+_35153749 1.45 ENSDART00000151073
si:ch211-195m9.3
chr2_+_42077559 1.45 ENSDART00000023208
ENSDARG00000014209
chr21_-_25358498 1.44 ENSDART00000167189
protein phosphatase methylesterase 1
chr8_+_36527653 1.43 ENSDART00000136418
ENSDART00000061378
splicing factor 3a, subunit 1
chr2_-_31849916 1.43 ENSDART00000109460
nucleolar protein 7
chr17_-_9794176 1.41

chr23_-_40642966 1.39 ENSDART00000153751
ring finger protein 146
chr12_-_3941450 1.38 ENSDART00000114857
protein phosphatase 4, catalytic subunit b
chr15_+_34734212 1.38 ENSDART00000099776
tetraspanin 13a
chr11_-_44734403 1.37 ENSDART00000160656
arylformamidase
chr7_-_26226628 1.37 ENSDART00000058910
SRY (sex determining region Y)-box 19b
chr7_-_73613763 1.37 ENSDART00000128137
zgc:92594
chr3_+_37507517 1.37 ENSDART00000075039
golgi SNAP receptor complex member 2
chr2_-_37650547 1.36 ENSDART00000008302
insulin receptor a
chr18_+_14715573 1.36 ENSDART00000108469
spermatogenesis associated 2-like
chr1_+_40894908 1.36 ENSDART00000111367
si:dkey-56e3.3
chr6_-_7529384 1.35 ENSDART00000091836
ENSDART00000151697
ubinuclein 2a
chr19_-_20819028 1.35 ENSDART00000136826
deleted in azoospermia-like
chr6_-_46740359 1.33 ENSDART00000011970
zgc:66479
chr1_-_50395003 1.32 ENSDART00000035150
spastin
chr10_-_44713414 1.32 ENSDART00000076084
nucleophosmin/nucleoplasmin, 2b
chr4_-_5100307 1.31 ENSDART00000138817
transmembrane protein 209
chr23_+_45486958 1.31 ENSDART00000111126
PC4 and SFRS1 interacting protein 1b
chr11_-_6442547 1.29 ENSDART00000137879
zgc:162969
chr12_+_33257120 1.27

chr25_+_20596613 1.27 ENSDART00000073648
KxDL motif containing 1
chr2_-_31850133 1.27 ENSDART00000109460
nucleolar protein 7
chr7_+_22042296 1.27 ENSDART00000123457
transmembrane protein 102
chr23_-_17502717 1.25

chr13_+_6091158 1.25 ENSDART00000025910
adipocyte plasma membrane associated protein
chr3_+_26212025 1.24 ENSDART00000163832
si:ch211-156b7.4
chr12_-_33257026 1.24 ENSDART00000066233
ENSDART00000148165
solute carrier family 16 (monocarboxylate transporter), member 3
chr7_+_13130111 1.23 ENSDART00000166318
diacylglycerol lipase, alpha
chr13_+_40347099 1.23

chr9_-_22014861 1.22 ENSDART00000101986
mitochondrial ribosomal protein L30
chr1_+_35253862 1.22 ENSDART00000139636
zgc:152968
chr19_-_18664670 1.21 ENSDART00000108627
sorting nexin 10a
chr10_-_35313462 1.21 ENSDART00000139107
proline rich 11
chr7_-_23623141 1.21

chr25_-_13307171 1.21 ENSDART00000056723
GINS complex subunit 3
chr23_-_40643077 1.19 ENSDART00000133356
ring finger protein 146
chr25_-_34596670 1.19 ENSDART00000171659
zgc:162611
chr16_-_30775394 1.19

chr21_+_20439227 1.19

chr9_+_31204464 1.18

chr23_+_22858063 1.18 ENSDART00000111345
arginine-glutamic acid dipeptide (RE) repeats a
chr5_+_19429620 1.16 ENSDART00000088819
ankyrin repeat domain 13A
chr10_-_11364807 1.15 ENSDART00000039145
ints3 and nabp interacting protein
chr5_+_31475897 1.15 ENSDART00000144510
zinc finger, matrin-type 5
chr24_+_29902165 1.14 ENSDART00000168422
ENSDART00000100092
ENSDART00000113304
ferric-chelate reductase 1b
chr15_-_16241412 1.14 ENSDART00000156352
si:ch211-259g3.4
chr14_-_33517822 1.13 ENSDART00000112268
oculocerebrorenal syndrome of Lowe
chr23_-_25208472 1.13 ENSDART00000103989
ENSDART00000160278
isocitrate dehydrogenase 3 (NAD+) gamma
chr8_+_21405821 1.13 ENSDART00000142758
si:dkey-163f12.10
chr9_-_22014768 1.13 ENSDART00000101986
mitochondrial ribosomal protein L30
chr15_-_47351885 1.13

chr3_+_39437497 1.13 ENSDART00000055170
ceroid-lipofuscinosis, neuronal 3
chr20_+_484286 1.13 ENSDART00000026794
5'-nucleotidase domain containing 1
chr4_-_4603294 1.12 ENSDART00000130601
ENSDARG00000090401
chr1_+_30925353 1.12 ENSDART00000057880
polymerase (DNA directed), lambda
chr21_+_10152870 1.10

chr3_+_37673971 1.10

chr22_+_699477 1.09 ENSDART00000017305
zinc finger protein 76
chr24_-_32668102 1.09 ENSDART00000066590
retinol dehydrogenase 12, like
chr5_-_20252709 1.09

chr18_+_15695287 1.09

chr5_-_11309164 1.08 ENSDART00000132564
neurofibromin 2a (merlin)
chr12_-_308764 1.08 ENSDART00000066579
ENSDART00000171396
6-pyruvoyltetrahydropterin synthase
chr24_+_36316070 1.08 ENSDART00000155260
retinoblastoma binding protein 8
chr14_+_51515192 1.05

chr12_+_47828020 1.04 ENSDART00000112010
leucine zipper, putative tumor suppressor 2b
chr3_+_37507573 1.04 ENSDART00000075039
golgi SNAP receptor complex member 2
chr10_+_35313772 1.03 ENSDART00000028940
serine/threonine/tyrosine interacting-like 1
chr22_+_35299551 1.01 ENSDART00000165353
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr7_+_13130177 1.01 ENSDART00000166318
diacylglycerol lipase, alpha
chr19_-_2928582 1.00 ENSDART00000109130
RecQ helicase-like 4
chr23_+_26099718 1.00 ENSDART00000141553
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr11_-_25224150 1.00 ENSDART00000014945
host cell factor C1a
chr8_+_42910733 1.00 ENSDART00000021715
solute carrier family 23 (ascorbic acid transporter), member 2
chr12_+_47097965 0.99 ENSDART00000084714
zinc finger, RAN-binding domain containing 1a
chr11_-_36425176 0.99 ENSDART00000156166
ENSDARG00000096865
chr8_-_22252628 0.99 ENSDART00000121513
nephronophthisis 4
chr23_+_29956616 0.98 ENSDART00000148706
aurora kinase A interacting protein 1
chr6_-_52725402 0.97 ENSDART00000033949
oxidative stress responsive serine-rich 1
chr8_-_44247277 0.97

chr17_+_48914379 0.97

chr11_-_10867083 0.96 ENSDART00000091901
proteasome 26S subunit, non-ATPase 14
chr23_-_40643024 0.96 ENSDART00000153751
ring finger protein 146
chr22_-_17571930 0.96

chr23_-_27647386 0.95

chr8_+_53202445 0.95

chr14_+_37317006 0.93

chr3_-_48458042 0.93 ENSDART00000156822
cell death-inducing p53 target 1
chr6_+_3556296 0.93 ENSDART00000041627
Sjogren syndrome antigen B (autoantigen La)
chr9_+_24084807 0.92 ENSDART00000131953
COP9 signalosome subunit 8
chr12_+_27151693 0.92 ENSDART00000066269
ADP-ribosylation factor-like 4D
chr25_+_3091855 0.92 ENSDART00000104859
RCC1 domain containing 1
chr7_+_8834029 0.92 ENSDART00000173250
proprotein convertase subtilisin/kexin type 6
chr21_-_25765319 0.91 ENSDART00000101219
methyltransferase like 27
chr13_+_35402766 0.91 ENSDART00000163368
ENSDART00000075414
ENSDART00000112947
WD repeat domain 27
chr11_-_8116290 0.90 ENSDART00000165569
tubulin tyrosine ligase-like family, member 7
chr10_+_43953171 0.88

chr21_-_1618494 0.87 ENSDART00000124904
zgc:152948
chr24_-_18732618 0.87 ENSDART00000092783
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr22_+_17235538 0.86 ENSDART00000134798
tudor domain containing 5
chr9_+_26029780 0.86 ENSDART00000127135
glycosyltransferase-like domain containing 1
chr8_-_53593850 0.86

chr5_+_58936508 0.85

chr20_+_25687135 0.84 ENSDART00000063122
cytochrome P450, family 2, subfamily P, polypeptide 10
chr24_+_16402587 0.84 ENSDART00000164319
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr7_-_48394268 0.83 ENSDART00000006378
cyclin-dependent kinase inhibitor 1Ca
chr5_+_19429500 0.83 ENSDART00000168868
ankyrin repeat domain 13A
chr8_-_31706783 0.82 ENSDART00000061832
si:dkey-46a10.3
chr23_-_29825098 0.82 ENSDART00000056865
catenin, beta interacting protein 1
chr4_+_13413303 0.82 ENSDART00000003694
cullin-associated and neddylation-dissociated 1
chr11_-_10472636 0.82 ENSDART00000081827
epithelial cell transforming 2
chr7_+_51499409 0.81 ENSDART00000007767
glutamic-oxaloacetic transaminase 2b, mitochondrial
chr14_-_10081301 0.81 ENSDART00000165101
COMM domain containing 5
chr19_-_43018998 0.81 ENSDART00000102583
synaptotagmin-like 1
chr14_+_23420053 0.81 ENSDART00000006373
Nedd4 family interacting protein 1
chr8_-_39850553 0.80 ENSDART00000131372
malectin
chr2_-_27892824 0.80

chr3_-_43393284 0.79 ENSDART00000157902
lysine (K)-specific demethylase 8
chr16_+_30393572 0.79

chr23_+_22954156 0.79

chr12_+_20000577 0.79 ENSDART00000161505
mahogunin, ring finger 1a
chr4_+_8669695 0.78 ENSDART00000168768
adiponectin receptor 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 11.8 GO:0060967 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
1.0 3.9 GO:0070986 left/right axis specification(GO:0070986)
0.5 2.6 GO:0099541 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.5 1.5 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.5 5.6 GO:0015671 oxygen transport(GO:0015671)
0.5 1.9 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.4 4.4 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.4 1.7 GO:1903726 negative regulation of phospholipid metabolic process(GO:1903726)
0.4 1.6 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.3 1.0 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.3 1.3 GO:0043243 positive regulation of protein complex disassembly(GO:0043243)
0.3 1.0 GO:0071947 protein K29-linked deubiquitination(GO:0035523) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) protein K33-linked deubiquitination(GO:1990168)
0.3 1.1 GO:0071871 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.3 1.1 GO:0015809 arginine transport(GO:0015809)
0.3 2.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.3 1.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.3 2.4 GO:0006591 ornithine metabolic process(GO:0006591)
0.3 1.6 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.3 0.8 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.3 2.0 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.2 1.0 GO:0015882 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.2 4.6 GO:0071218 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.2 0.8 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 1.0 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.2 1.5 GO:0051013 microtubule severing(GO:0051013)
0.2 4.0 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.2 1.2 GO:1902292 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.2 1.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.2 0.5 GO:0010265 SCF complex assembly(GO:0010265)
0.2 0.8 GO:1903513 endoplasmic reticulum to cytosol transport(GO:1903513)
0.1 1.0 GO:1904491 protein localization to ciliary transition zone(GO:1904491) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 6.1 GO:0007599 blood coagulation(GO:0007596) hemostasis(GO:0007599)
0.1 2.5 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1 3.0 GO:0030593 neutrophil chemotaxis(GO:0030593)
0.1 0.5 GO:0031645 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.1 1.6 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.9 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.8 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.1 3.5 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 1.7 GO:0032418 lysosome localization(GO:0032418)
0.1 0.3 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.8 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 0.7 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.1 1.0 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.1 1.0 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.1 0.3 GO:0046950 cellular ketone body metabolic process(GO:0046950) ketone body metabolic process(GO:1902224)
0.1 0.6 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.1 0.9 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.7 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.1 1.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 3.4 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.1 1.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.8 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.1 0.3 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1 1.4 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.1 0.4 GO:0030262 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.1 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.1 1.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.5 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 1.6 GO:0006094 gluconeogenesis(GO:0006094)
0.1 0.4 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.1 0.2 GO:1903010 positive regulation of cilium assembly(GO:0045724) regulation of bone development(GO:1903010)
0.1 1.7 GO:0032465 regulation of cytokinesis(GO:0032465)
0.1 1.1 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 2.0 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.3 GO:0030817 regulation of cAMP metabolic process(GO:0030814) regulation of cAMP biosynthetic process(GO:0030817) regulation of adenylate cyclase activity(GO:0045761)
0.0 1.4 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0097354 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.6 GO:0031297 replication fork processing(GO:0031297)
0.0 0.4 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 1.5 GO:0009620 response to yeast(GO:0001878) response to fungus(GO:0009620)
0.0 0.7 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.1 GO:0070126 mitochondrial translational termination(GO:0070126)
0.0 1.1 GO:0010212 response to ionizing radiation(GO:0010212)
0.0 0.8 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.8 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.1 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0046498 S-adenosylmethionine cycle(GO:0033353) S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 1.2 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.7 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.5 GO:0000266 mitochondrial fission(GO:0000266)
0.0 1.0 GO:0000723 telomere maintenance(GO:0000723) telomere organization(GO:0032200)
0.0 0.2 GO:0006895 phagolysosome assembly(GO:0001845) Golgi to endosome transport(GO:0006895)
0.0 0.6 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.5 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.4 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.2 GO:0035794 positive regulation of mitochondrial membrane permeability(GO:0035794) mitochondrial outer membrane permeabilization(GO:0097345) positive regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902110) mitochondrial outer membrane permeabilization involved in programmed cell death(GO:1902686)
0.0 0.2 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.3 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0 0.2 GO:0098781 ncRNA transcription(GO:0098781)
0.0 0.6 GO:0006096 glycolytic process(GO:0006096)
0.0 0.6 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of chemotaxis(GO:0050922) negative regulation of axon guidance(GO:1902668)
0.0 0.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.3 GO:0007520 myoblast fusion(GO:0007520)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0033391 chromatoid body(GO:0033391)
0.5 2.7 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.3 1.0 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.2 1.7 GO:0031838 hemoglobin complex(GO:0005833) haptoglobin-hemoglobin complex(GO:0031838)
0.2 1.2 GO:0000811 GINS complex(GO:0000811)
0.2 1.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.2 1.1 GO:0070876 SOSS complex(GO:0070876)
0.2 1.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.4 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.4 GO:0070390 transcription export complex 2(GO:0070390)
0.1 2.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.0 GO:0005899 insulin receptor complex(GO:0005899)
0.1 1.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.3 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 1.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 1.5 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.6 GO:0035101 FACT complex(GO:0035101)
0.1 0.7 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.9 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.4 GO:0008623 CHRAC(GO:0008623)
0.1 0.8 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 2.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 3.6 GO:0030496 midbody(GO:0030496)
0.1 1.0 GO:0097546 ciliary base(GO:0097546)
0.1 1.5 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.3 GO:0070985 TFIIK complex(GO:0070985)
0.1 1.9 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 1.6 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.5 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 1.0 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.3 GO:0044545 NSL complex(GO:0044545)
0.0 2.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 5.5 GO:0010008 endosome membrane(GO:0010008)
0.0 1.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.3 GO:0035060 brahma complex(GO:0035060)
0.0 2.2 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 0.9 GO:0022627 cytosolic ribosome(GO:0022626) cytosolic small ribosomal subunit(GO:0022627)
0.0 1.2 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.1 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 2.1 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 14.0 GO:0005654 nucleoplasm(GO:0005654)
0.0 1.0 GO:0005769 early endosome(GO:0005769)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.1 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.0 0.4 GO:0005876 spindle microtubule(GO:0005876)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 11.8 GO:0008494 translation activator activity(GO:0008494)
0.9 3.5 GO:0072572 poly-ADP-D-ribose binding(GO:0072572)
0.7 3.9 GO:0098809 nitrite reductase activity(GO:0098809)
0.6 2.4 GO:0016842 amidine-lyase activity(GO:0016842)
0.5 1.6 GO:0000403 Y-form DNA binding(GO:0000403) double-strand/single-strand DNA junction binding(GO:0000406) flap-structured DNA binding(GO:0070336)
0.5 1.5 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.5 1.9 GO:0004061 arylformamidase activity(GO:0004061)
0.4 2.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.4 1.3 GO:0016843 amine-lyase activity(GO:0016843) strictosidine synthase activity(GO:0016844)
0.4 1.1 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.3 1.8 GO:0016972 flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
0.3 1.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.3 1.9 GO:0005537 mannose binding(GO:0005537)
0.3 1.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.3 4.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 1.7 GO:0031720 haptoglobin binding(GO:0031720)
0.2 0.7 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.2 0.7 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.2 1.5 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.2 2.5 GO:2001069 glycogen binding(GO:2001069)
0.2 1.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 1.0 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 6.1 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 1.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.4 GO:0003874 6-pyruvoyltetrahydropterin synthase activity(GO:0003874)
0.1 1.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 1.0 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.1 3.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.7 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.1 1.7 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.5 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 1.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 1.8 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 1.1 GO:0034595 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.1 0.3 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 0.5 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 0.7 GO:0050699 WW domain binding(GO:0050699)
0.1 1.0 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.8 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.6 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 2.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.1 GO:0015166 polyol transmembrane transporter activity(GO:0015166) glycerol transmembrane transporter activity(GO:0015168)
0.0 2.0 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0048531 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.8 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.3 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 1.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 5.2 GO:0042393 histone binding(GO:0042393)
0.0 0.8 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 3.0 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 0.1 GO:0016801 hydrolase activity, acting on ether bonds(GO:0016801)
0.0 0.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 2.7 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.0 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 1.4 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 2.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.4 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.6 GO:0048029 monosaccharide binding(GO:0048029)
0.0 0.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.9 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 2.2 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 1.3 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 4.9 GO:0004674 protein serine/threonine kinase activity(GO:0004674)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 3.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 2.4 PID ARF 3PATHWAY Arf1 pathway
0.1 0.7 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 1.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 2.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 1.6 PID ATM PATHWAY ATM pathway
0.1 1.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.0 PID AURORA A PATHWAY Aurora A signaling
0.0 1.1 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.3 PID IGF1 PATHWAY IGF1 pathway
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.4 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.2 PID MYC PATHWAY C-MYC pathway
0.0 0.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 2.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 1.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.0 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.7 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 1.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.3 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.1 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 0.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.8 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.7 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.7 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+