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DANIO-CODE

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Results for en1a

Z-value: 0.67

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Transcription factors associated with en1a

Gene Symbol Gene ID Gene Info
en1a
ENSDARG00000014321 engrailed homeobox 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
en1adr10_dc_chr9_-_785569_785606-0.774.6e-04Click!

Activity profile of en1a motif

Sorted Z-values of en1a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of en1a

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr25_-_36621626 1.90 ENSDART00000128108
urahb
urate (5-hydroxyiso-) hydrolase b
chr3_-_39316317 1.77

chr1_+_41762057 1.55 ENSDART00000137609
ctnna2
catenin (cadherin-associated protein), alpha 2
chr2_-_2373601 1.42 ENSDART00000113774
si:ch211-188c16.1
si:ch211-188c16.1
chr23_-_33812361 1.34 ENSDART00000136386
si:ch211-210c8.7
si:ch211-210c8.7
chr13_+_8508786 1.25 ENSDART00000059321
epcam
epithelial cell adhesion molecule
chr9_-_11616001 1.24 ENSDART00000030995
umps
uridine monophosphate synthetase
chr24_-_9865837 1.20 ENSDART00000106244
zgc:171750
zgc:171750
chr1_+_21964075 1.17 ENSDART00000161874
anxa5b
annexin A5b
chr17_-_1524813 1.12 ENSDART00000112803
wdr20a
WD repeat domain 20a
chr6_+_39186673 1.11 ENSDART00000156187
tac3b
tachykinin 3b
chr10_-_25448769 1.10 ENSDART00000140023
grik1a
glutamate receptor, ionotropic, kainate 1a
chr23_+_6652454 1.10 ENSDART00000081763
rbm38
RNA binding motif protein 38
chr18_-_12889296 1.09 ENSDART00000130343
parp12a
poly (ADP-ribose) polymerase family, member 12a
chr23_+_19663746 1.06 ENSDART00000170149
slmapb
sarcolemma associated protein b
chr17_-_31387062 1.01

chr3_-_27515161 0.97 ENSDART00000151027
si:ch211-157c3.4
si:ch211-157c3.4
chr21_-_7322856 0.91 ENSDART00000151543
ENSDART00000114982
f2rl1.2
coagulation factor II (thrombin) receptor-like 1, tandem duplicate 2
chr5_-_32433490 0.89

chr16_+_47283253 0.89 ENSDART00000062507
ica1
islet cell autoantigen 1
chr16_+_41065840 0.88 ENSDART00000124543
dek
DEK proto-oncogene
chr24_-_16835352 0.87 ENSDART00000005331
ENSDART00000128446
klhl15
kelch-like family member 15
chr17_-_18777398 0.86 ENSDART00000045991
vrk1
vaccinia related kinase 1
chr5_+_58883315 0.85

chr2_+_36623514 0.85 ENSDART00000098415
ing5b
inhibitor of growth family, member 5b
chr14_-_47210912 0.81 ENSDART00000031640
ENSDART00000132966
zgc:113425
zgc:113425
chr12_-_10327938 0.79 ENSDART00000007335
ndc80
NDC80 kinetochore complex component
chr5_-_41396159 0.79 ENSDART00000143573
ncor1
nuclear receptor corepressor 1
chr19_-_3547196 0.75 ENSDART00000166107
hivep1
human immunodeficiency virus type I enhancer binding protein 1
chr23_-_17055508 0.75 ENSDART00000125472
dnmt3bb.3
DNA (cytosine-5-)-methyltransferase beta, duplicate b.3
chr18_+_19467527 0.74 ENSDART00000079695
zwilch
zwilch kinetochore protein
chr7_-_18460264 0.73 ENSDART00000173905
trmt10a
tRNA methyltransferase 10A
chr5_-_57053687 0.72 ENSDART00000144237
gig2p
grass carp reovirus (GCRV)-induced gene 2p
chr10_-_22180856 0.72 ENSDART00000006173
cldn7b
claudin 7b
chr7_-_20330881 0.71 ENSDART00000169750
si:dkey-19b23.11
si:dkey-19b23.11
chr18_-_12889369 0.69 ENSDART00000130343
parp12a
poly (ADP-ribose) polymerase family, member 12a
chr3_-_42949449 0.68 ENSDART00000161127
axin1
axin 1
chr7_+_26730804 0.68

chr22_+_818795 0.68 ENSDART00000003325
dennd2db
DENN/MADD domain containing 2Db
chr13_+_8509344 0.68 ENSDART00000140489
epcam
epithelial cell adhesion molecule
chr20_+_52021000 0.68 ENSDART00000074330
taf1a
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A
chr14_+_23420053 0.67 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr10_-_22180935 0.67 ENSDART00000006173
cldn7b
claudin 7b
chr12_-_20494169 0.67 ENSDART00000105362
snx11
sorting nexin 11
chr3_-_26060787 0.66 ENSDART00000113843
ypel3
yippee-like 3
chr6_+_38898605 0.65 ENSDART00000029930
slc48a1b
solute carrier family 48 (heme transporter), member 1b
chr3_-_21006698 0.63 ENSDART00000104051
cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr25_+_34555948 0.63 ENSDART00000111706
si:dkey-108k21.14
si:dkey-108k21.14
chr3_-_42949616 0.63 ENSDART00000161127
axin1
axin 1
chr21_-_31215463 0.62 ENSDART00000170507
crcp
calcitonin gene-related peptide-receptor component protein
chr21_-_21787648 0.62 ENSDART00000030984
wdr73
WD repeat domain 73
chr19_+_12730217 0.62 ENSDART00000088917
rnmt
RNA (guanine-7-) methyltransferase
chr19_+_43316957 0.62 ENSDART00000151298
arpp21
cAMP-regulated phosphoprotein, 21
chr10_-_25448712 0.60 ENSDART00000140023
grik1a
glutamate receptor, ionotropic, kainate 1a
chr12_+_9811557 0.60 ENSDART00000110458
fam117ab
family with sequence similarity 117, member Ab
chr7_+_28824986 0.59 ENSDART00000052349
ogfod1
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr17_+_13292569 0.59 ENSDART00000177104
BX005308.2
ENSDARG00000108498
chr2_+_37855019 0.58 ENSDART00000113337
parp2
poly (ADP-ribose) polymerase 2
chr12_-_26445609 0.58 ENSDART00000132737
ENSDART00000163931
acsf2
acyl-CoA synthetase family member 2
chr2_-_26934833 0.58 ENSDART00000025120
ndc1
NDC1 transmembrane nucleoporin
chr3_-_42949526 0.57 ENSDART00000161127
axin1
axin 1
chr5_+_60782855 0.56 ENSDART00000074073
alkbh4
alkB homolog 4, lysine demthylase
chr2_+_38042821 0.55 ENSDART00000134211
ENSDART00000144868
hnrnpc
heterogeneous nuclear ribonucleoprotein C
chr22_+_18840143 0.54

chr23_-_17055376 0.54 ENSDART00000125472
dnmt3bb.3
DNA (cytosine-5-)-methyltransferase beta, duplicate b.3
chr18_+_12853364 0.54

chr6_+_38898811 0.54 ENSDART00000131347
slc48a1b
solute carrier family 48 (heme transporter), member 1b
chr21_-_21787540 0.53 ENSDART00000030984
wdr73
WD repeat domain 73
chr16_-_10946422 0.52 ENSDART00000036891
rabac1
Rab acceptor 1 (prenylated)
chr17_+_5776013 0.52 ENSDART00000168326
znf513b
zinc finger protein 513b
chr18_-_16927749 0.52 ENSDART00000100105
ENSDART00000163400
swap70b
SWAP switching B-cell complex 70b subunit 70b
chr21_-_9291682 0.51 ENSDART00000169275
sdad1
SDA1 domain containing 1
chr7_-_46940193 0.50 ENSDART00000161558
BX005073.2
ENSDARG00000099964
chr3_-_42949479 0.50 ENSDART00000161127
axin1
axin 1
chr19_-_3849408 0.50 ENSDART00000165917
btr18
bloodthirsty-related gene family, member 18
chr17_-_1524751 0.49 ENSDART00000112803
wdr20a
WD repeat domain 20a
chr22_-_24957034 0.49 ENSDART00000142147
dnal4b
dynein, axonemal, light chain 4b
chr2_-_22875246 0.49 ENSDART00000159641
znf644a
zinc finger protein 644a
chr16_+_54906490 0.48 ENSDART00000126646
ENSDARG00000091079
ENSDARG00000091079
chr25_+_18997440 0.47 ENSDART00000155569
si:dkeyp-19h3.8
si:dkeyp-19h3.8
chr21_-_9291452 0.47 ENSDART00000169275
sdad1
SDA1 domain containing 1
chr10_+_15382807 0.47 ENSDART00000168909
trappc13
trafficking protein particle complex 13
chr17_-_1524721 0.46 ENSDART00000112803
wdr20a
WD repeat domain 20a
chr24_+_10162691 0.45 ENSDART00000066794
ENSDART00000112455
otulina
otulina
OTU deubiquitinase with linear linkage specificity a
OTU deubiquitinase with linear linkage specificity a
chr12_-_10343382 0.45 ENSDART00000152788
mki67
marker of proliferation Ki-67
chr2_-_22836607 0.44 ENSDART00000168022
gtf2b
general transcription factor IIB
chr3_-_29779725 0.44 ENSDART00000151501
RUNDC1
RUN domain containing 1
chr2_+_45119713 0.43 ENSDART00000075146
alg3
asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase)
chr7_+_28825033 0.43 ENSDART00000052349
ogfod1
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr23_-_17055458 0.42 ENSDART00000125472
dnmt3bb.3
DNA (cytosine-5-)-methyltransferase beta, duplicate b.3
chr20_-_37910887 0.41 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr20_-_44562847 0.41 ENSDART00000085442
mut
methylmalonyl CoA mutase
chr24_+_35296732 0.41 ENSDART00000172652
pcmtd1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr9_-_12623750 0.41 ENSDART00000142024
tra2b
transformer 2 beta homolog
chr6_-_53391354 0.40 ENSDART00000155483
si:ch211-161c3.6
si:ch211-161c3.6
chr4_+_5823740 0.40 ENSDART00000121743
si:ch73-352p4.5
si:ch73-352p4.5
chr3_-_29779598 0.40 ENSDART00000151501
RUNDC1
RUN domain containing 1
chr24_-_8585312 0.38

chr12_+_23939869 0.38 ENSDART00000021298
asb3
ankyrin repeat and SOCS box containing 3
chr23_-_21608362 0.38 ENSDART00000010647
rcc2
regulator of chromosome condensation 2
chr20_-_34244538 0.37 ENSDART00000152963
BX248238.2
ENSDARG00000096789
chr17_-_9794176 0.36

chr3_-_33362384 0.36 ENSDART00000020342
sgsm3
small G protein signaling modulator 3
chr12_-_25006119 0.36 ENSDART00000158036
cript
cysteine-rich PDZ-binding protein
chr23_+_116397 0.36

chr21_-_10962154 0.35 ENSDART00000084061
nedd4l
neural precursor cell expressed, developmentally down-regulated 4-like
chr4_+_25923205 0.35 ENSDART00000136927
vetz
vezatin, adherens junctions transmembrane protein
chr18_+_41242278 0.34 ENSDART00000138552
ENSDART00000145863
trip12
thyroid hormone receptor interactor 12
chr21_-_31215400 0.34 ENSDART00000121946
crcp
calcitonin gene-related peptide-receptor component protein
chr9_+_23192282 0.34 ENSDART00000021060
eaf2
ELL associated factor 2
chr4_+_10605257 0.34 ENSDART00000122636
ENSDART00000037140
ing3
inhibitor of growth family, member 3
chr20_-_26517489 0.34

chr4_+_13490875 0.33 ENSDART00000178376
BX465210.1
ENSDARG00000107553
chr15_+_14918610 0.33 ENSDART00000163066
diabloa
diablo, IAP-binding mitochondrial protein a
chr23_-_25853364 0.33 ENSDART00000110670
ENSDARG00000078574
ENSDARG00000078574
chr18_-_7138414 0.31 ENSDART00000003748
cfap161
cilia and flagella associated protein 161
chr18_-_510340 0.30 ENSDART00000164374
si:ch211-79l17.1
si:ch211-79l17.1
chr5_+_23559435 0.29 ENSDART00000142268
gps2
G protein pathway suppressor 2
chr3_-_29779552 0.29 ENSDART00000151501
RUNDC1
RUN domain containing 1
chr10_+_20435169 0.29 ENSDART00000160803
r3hcc1
R3H domain and coiled-coil containing 1
chr14_-_43204831 0.28 ENSDART00000122339
gar1
GAR1 homolog, ribonucleoprotein
chr23_+_22408825 0.28 ENSDART00000147696
rap1gap
RAP1 GTPase activating protein
chr2_-_7772932 0.28 ENSDART00000160053
ripk2
receptor-interacting serine-threonine kinase 2
chr25_-_28920272 0.28 ENSDART00000166889
nptna
neuroplastin a
chr11_-_35494404 0.27 ENSDART00000103076
arl8bb
ADP-ribosylation factor-like 8Bb
chr1_-_29764204 0.27 ENSDART00000144297
ENSDART00000164204
ubac2
UBA domain containing 2
chr3_+_32802899 0.27

chr22_-_10410949 0.27 ENSDART00000111962
ENSDART00000064809
nol8
nucleolar protein 8
chr22_-_28695519 0.27 ENSDART00000005883
ENSDART00000007791
jagn1b
jagunal homolog 1b
chr16_+_19223553 0.27 ENSDART00000115263
ENSDART00000114954
rapgef5b
Rap guanine nucleotide exchange factor (GEF) 5b
chr23_-_26193648 0.27 ENSDART00000164032
rca2.1
regulator of complement activation group 2 gene 1
chr14_-_40482957 0.27 ENSDART00000173236
ef1
E74-like factor 1 (ets domain transcription factor)
chr4_-_5822882 0.26 ENSDART00000008898
foxm1
forkhead box M1
chr10_+_44846866 0.26

chr1_-_37452112 0.26 ENSDART00000142811
hmgb2a
high mobility group box 2a
chr15_+_35185174 0.26 ENSDART00000086954
ENSDART00000161594
sesn3
sestrin 3
chr5_+_53633496 0.26 ENSDART00000166050
rangrf
RAN guanine nucleotide release factor
chr19_-_307085 0.26 ENSDART00000145916
lingo4a
leucine rich repeat and Ig domain containing 4a
chr6_-_22910576 0.26 ENSDART00000164114
grb2a
growth factor receptor-bound protein 2a
chr11_-_6870810 0.24 ENSDART00000007204
ddx49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr5_-_68943821 0.24 ENSDART00000158956
mob1a
MOB kinase activator 1A
chr5_+_23559189 0.23 ENSDART00000142268
gps2
G protein pathway suppressor 2
chr24_-_16835253 0.23 ENSDART00000005331
ENSDART00000128446
klhl15
kelch-like family member 15
chr15_+_17505794 0.21 ENSDART00000153729
snx19b
sorting nexin 19b
chr14_-_7000549 0.21 ENSDART00000158914
si:ch211-51f19.1
si:ch211-51f19.1
chr24_+_35296642 0.21 ENSDART00000172652
pcmtd1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr17_-_5918853 0.21 ENSDART00000058890
ENSDART00000171084
ephx2
epoxide hydrolase 2, cytoplasmic
chr13_-_34732375 0.21

chr8_+_36951655 0.20

chr6_+_32339159 0.20 ENSDART00000042134
dock7
dedicator of cytokinesis 7
chr1_+_40763274 0.19 ENSDART00000135280
paip2b
poly(A) binding protein interacting protein 2B
chr4_-_29167253 0.18 ENSDART00000160579
CR388132.2
ENSDARG00000101782
chr7_-_6334242 0.18 ENSDART00000081359
zgc:110425
zgc:110425
chr11_-_6870835 0.18 ENSDART00000007204
ddx49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr7_+_49391403 0.17 ENSDART00000131210
rassf7b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr7_+_32626787 0.17 ENSDART00000140800
ENSDART00000075263
ENSDART00000137956
tssc4
tumor suppressing subtransferable candidate 4
chr23_-_17055590 0.16 ENSDART00000143180
dnmt3bb.3
DNA (cytosine-5-)-methyltransferase beta, duplicate b.3
chr1_+_40762892 0.16 ENSDART00000010211
paip2b
poly(A) binding protein interacting protein 2B
chr15_-_26998580 0.16 ENSDART00000027563
ccdc9
coiled-coil domain containing 9
chr3_+_60035494 0.15 ENSDART00000166982
ENSDART00000166837
sec14l1
SEC14-like lipid binding 1
chr5_-_68943600 0.15 ENSDART00000159851
mob1a
MOB kinase activator 1A
chr2_-_4277605 0.15

chr20_-_26517630 0.15

chr10_+_16207230 0.15 ENSDART00000065045
prrc1
proline-rich coiled-coil 1
chr16_-_10946309 0.15 ENSDART00000049148
rabac1
Rab acceptor 1 (prenylated)
chr25_-_26309649 0.14 ENSDART00000156364
usp3
ubiquitin specific peptidase 3
chr1_-_37452393 0.13 ENSDART00000047159
hmgb2a
high mobility group box 2a
chr1_-_54453712 0.13 ENSDART00000074083
rab1aa
RAB1A, member RAS oncogene family a
chr14_-_30150071 0.13 ENSDART00000173107
micu3b
mitochondrial calcium uptake family, member 3b
chr7_-_33791033 0.12 ENSDART00000052404
map2k5
mitogen-activated protein kinase kinase 5
chr6_-_19556328 0.11 ENSDART00000074256
ppp1r12c
protein phosphatase 1, regulatory subunit 12C
chr23_-_25853331 0.11 ENSDART00000110670
ENSDARG00000078574
ENSDARG00000078574
chr1_-_37451594 0.11 ENSDART00000142811
hmgb2a
high mobility group box 2a
chr7_-_6231350 0.10 ENSDART00000159524
CU457819.1
Histone H3.2
chr6_-_8156520 0.08 ENSDART00000081561
ilf3a
interleukin enhancer binding factor 3a
chr9_+_12473243 0.08 ENSDART00000132709
tmem41aa
transmembrane protein 41aa
chr25_-_26309873 0.08 ENSDART00000155698
usp3
ubiquitin specific peptidase 3
chr16_+_23468242 0.08 ENSDART00000103220
krtcap2
keratinocyte associated protein 2
chr11_-_26463925 0.08 ENSDART00000083010
acad9
acyl-CoA dehydrogenase family, member 9
chr9_-_21042485 0.07 ENSDART00000028247
gdap2
ganglioside induced differentiation associated protein 2
chr25_+_18997277 0.07 ENSDART00000154066
isg20
interferon stimulated exonuclease gene
chr3_-_23466232 0.07 ENSDART00000156897
ube2z
ubiquitin-conjugating enzyme E2Z
chr18_-_29920047 0.07 ENSDART00000138533
cmc2
C-x(9)-C motif containing 2
chr12_-_3803808 0.06 ENSDART00000160967
taok2b
TAO kinase 2b
chr21_+_34780385 0.05 ENSDART00000003962
wdr55
WD repeat domain 55
chr9_-_30744878 0.05 ENSDART00000079222
chaf1b
chromatin assembly factor 1, subunit B
chr14_+_10984191 0.05 ENSDART00000113567
rlim
ring finger protein, LIM domain interacting
chr3_-_42949225 0.05 ENSDART00000161127
axin1
axin 1
chr20_-_33887129 0.05 ENSDART00000020183
fam102bb
family with sequence similarity 102, member B, b
chr15_+_14918997 0.05 ENSDART00000164119
diabloa
diablo, IAP-binding mitochondrial protein a
chr16_+_17706214 0.05

chr4_-_4241386 0.04 ENSDART00000103316
cd9b
CD9 molecule b
chr3_+_40265548 0.04 ENSDART00000103486
tnrc18
trinucleotide repeat containing 18
chr13_-_9543393 0.04 ENSDART00000041609
tm9sf3
transmembrane 9 superfamily member 3
chr16_+_24047736 0.03

chr18_+_41242323 0.03 ENSDART00000138552
ENSDART00000145863
trip12
thyroid hormone receptor interactor 12
chr15_-_34700453 0.03 ENSDART00000140882
ispd
isoprenoid synthase domain containing
chr9_+_1363455 0.02 ENSDART00000140917
prkra
protein kinase, interferon-inducible double stranded RNA dependent activator
chr18_-_14932910 0.02 ENSDART00000145842
trabd
TraB domain containing
chr5_+_58017820 0.02 ENSDART00000083015
ccdc84
coiled-coil domain containing 84

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.3 2.4 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.3 0.9 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.3 0.9 GO:0090166 Golgi disassembly(GO:0090166)
0.3 1.1 GO:0045777 positive regulation of blood pressure(GO:0045777)
0.2 1.2 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.2 0.5 GO:0048714 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.2 1.0 GO:0006449 regulation of translational termination(GO:0006449)
0.2 1.0 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.2 0.8 GO:1901976 regulation of cell cycle checkpoint(GO:1901976)
0.1 0.7 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.1 1.4 GO:0060876 semicircular canal formation(GO:0060876)
0.1 1.2 GO:0050819 negative regulation of coagulation(GO:0050819)
0.1 0.7 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 0.4 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 0.6 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 1.2 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 0.6 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 1.4 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 1.9 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.1 0.5 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 1.1 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 1.0 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 0.6 GO:0006999 nuclear pore organization(GO:0006999)
0.1 1.7 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 0.9 GO:0050796 regulation of insulin secretion(GO:0050796)
0.1 0.6 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 1.9 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.1 0.8 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.1 0.4 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.3 GO:0050832 neutrophil mediated immunity(GO:0002446) defense response to fungus(GO:0050832)
0.1 0.6 GO:0070989 oxidative demethylation(GO:0070989)
0.0 0.4 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.3 GO:0033183 regulation of histone ubiquitination(GO:0033182) negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.3 GO:0071233 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 0.9 GO:2000779 regulation of double-strand break repair(GO:2000779)
0.0 0.4 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.3 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.3 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.5 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.7 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.4 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.3 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.0 0.4 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.7 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.2 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.3 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.3 GO:0060029 convergent extension involved in organogenesis(GO:0060029)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 0.7 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.2 0.8 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.5 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.1 0.9 GO:0030667 secretory granule membrane(GO:0030667)
0.1 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.8 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.6 GO:0070938 contractile ring(GO:0070938)
0.1 0.3 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.6 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.4 GO:0071797 LUBAC complex(GO:0071797)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.3 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 1.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.3 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 1.4 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.5 GO:0030286 dynein complex(GO:0030286)
0.0 0.6 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 1.5 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.4 GO:0030496 midbody(GO:0030496)
0.0 0.6 GO:0005643 nuclear pore(GO:0005643)
0.0 1.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.8 GO:0030424 axon(GO:0030424)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0033971 hydroxyisourate hydrolase activity(GO:0033971)
0.3 0.9 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 0.6 GO:0004482 mRNA (guanine-N7-)-methyltransferase activity(GO:0004482)
0.2 0.7 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.2 1.7 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.6 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 0.6 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.6 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 2.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.2 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.7 GO:0050699 WW domain binding(GO:0050699)
0.1 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 1.2 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.1 1.0 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.1 0.4 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
0.1 1.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.2 GO:0016803 ether hydrolase activity(GO:0016803)
0.1 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.0 2.2 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 1.2 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 0.4 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 1.6 GO:0045296 cadherin binding(GO:0045296)
0.0 1.0 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.6 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.6 GO:0032451 demethylase activity(GO:0032451)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 0.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling
0.0 1.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.1 ST GA12 PATHWAY G alpha 12 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.2 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.6 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 1.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein