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DANIO-CODE

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Results for esr1

Z-value: 1.16

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Transcription factors associated with esr1

Gene Symbol Gene ID Gene Info
esr1
ENSDARG00000004111 estrogen receptor 1

Activity profile of esr1 motif

Sorted Z-values of esr1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of esr1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr10_-_44180588 4.71 ENSDART00000145404
crybb1
crystallin, beta B1
chr18_+_62936 3.59 ENSDART00000052638
slc27a2a
solute carrier family 27 (fatty acid transporter), member 2a
chr5_-_70948223 3.29 ENSDART00000013404
ak1
adenylate kinase 1
chr7_+_19765237 3.19 ENSDART00000100808
bcl6b
B-cell CLL/lymphoma 6, member B
chr23_+_44817648 2.81 ENSDART00000143688
dlg4b
discs, large homolog 4b (Drosophila)
chr18_-_39491932 2.80 ENSDART00000122930
scg3
secretogranin III
chr18_-_15405161 2.75 ENSDART00000031752
rfx4
regulatory factor X, 4
chr7_+_40603904 2.74 ENSDART00000149395
shha
sonic hedgehog a
chr3_+_39425125 2.64 ENSDART00000146867
aldoaa
aldolase a, fructose-bisphosphate, a
chr6_+_55022668 2.61 ENSDART00000158845
mybphb
myosin binding protein Hb
chr11_+_11217547 2.59 ENSDART00000087105
myom2a
myomesin 2a
chr7_+_40604000 2.55 ENSDART00000149395
shha
sonic hedgehog a
chr16_+_29716279 2.42 ENSDART00000137153
tmod4
tropomodulin 4 (muscle)
chr4_-_1346961 2.23 ENSDART00000164623
ptn
pleiotrophin
chr22_+_33177432 2.22 ENSDART00000126885
dag1
dystroglycan 1
chr5_-_36237656 2.18 ENSDART00000032481
ckma
creatine kinase, muscle a
chr9_-_22528568 2.17 ENSDART00000134805
crygm2d1
crystallin, gamma M2d1
chr2_-_24275851 2.13 ENSDART00000121885
tgfbr1a
transforming growth factor, beta receptor 1 a
chr3_+_26013873 2.12 ENSDART00000043932
atp2a1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr15_+_24708696 2.07 ENSDART00000043292
smtnl
smoothelin, like
chr9_-_53220424 2.03

chr1_+_53286155 2.03 ENSDART00000139625
acta1a
actin, alpha 1a, skeletal muscle
chr2_-_24357532 1.96 ENSDART00000137065
col15a1b
collagen, type XV, alpha 1b
chr6_-_13654186 1.95 ENSDART00000150102
ENSDART00000041269
cryba2a
crystallin, beta A2a
chr5_-_46382728 1.93

chr25_-_30818836 1.92 ENSDART00000156828
prr33
proline rich 33
chr18_+_6551983 1.86 ENSDART00000160382
ENSDART00000171495
ENSDART00000160228
fam168a
family with sequence similarity 168, member A
chr23_-_26150495 1.85 ENSDART00000126299
gdi1
GDP dissociation inhibitor 1
chr24_-_12794057 1.84 ENSDART00000024084
pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr24_-_39722595 1.81 ENSDART00000066506
cox6b1
cytochrome c oxidase subunit VIb polypeptide 1
chr11_-_6051096 1.77 ENSDART00000147761
vsg1
vessel-specific 1
chr12_-_43939028 1.76 ENSDART00000170723
zgc:112964
zgc:112964
chr12_+_27032862 1.75

chr18_+_31038010 1.74 ENSDART00000163471
uraha
urate (5-hydroxyiso-) hydrolase a
chr18_-_15404998 1.72 ENSDART00000031752
rfx4
regulatory factor X, 4
chr22_-_15567180 1.68 ENSDART00000123125
tpm4a
tropomyosin 4a
chr24_-_12794564 1.68 ENSDART00000024084
pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr5_-_54773058 1.68 ENSDART00000145791
prune2
prune homolog 2 (Drosophila)
chr11_+_7148830 1.67 ENSDART00000035560
tmem38a
transmembrane protein 38A
chr2_+_42342148 1.67 ENSDART00000144716
cavin4a
caveolae associated protein 4a
chr8_-_23102555 1.65

chr21_+_40082890 1.64 ENSDART00000100166
serpinf1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr20_-_24223659 1.64 ENSDART00000153464
bach2b
BTB and CNC homology 1, basic leucine zipper transcription factor 2b
chr22_-_120677 1.63

chr4_+_4841191 1.61 ENSDART00000130818
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr3_+_23587156 1.61

chr16_+_24057260 1.60 ENSDART00000132742
ENSDART00000145330
apoc1
apolipoprotein C-I
chr14_-_136402 1.59

chr22_+_11726312 1.59 ENSDART00000155366
krt96
keratin 96
chr6_+_41466199 1.59 ENSDART00000177439
twf2a
twinfilin actin-binding protein 2a
chr2_-_28446615 1.56 ENSDART00000179495
cdh6
cadherin 6
chr22_+_18218979 1.56

chr10_+_4962403 1.56 ENSDART00000134679
CU074419.2
ENSDARG00000093688
chr4_+_18974767 1.55 ENSDART00000066973
impdh1b
IMP (inosine 5'-monophosphate) dehydrogenase 1b
chr15_-_20297270 1.55 ENSDART00000123910
ppp1r14ab
protein phosphatase 1, regulatory (inhibitor) subunit 14Ab
chr12_-_4648262 1.55 ENSDART00000152771
si:ch211-255p10.3
si:ch211-255p10.3
chr9_-_7560915 1.55 ENSDART00000081553
desma
desmin a
chr23_+_6298911 1.54 ENSDART00000139795
syt2a
synaptotagmin IIa
chr10_-_22881453 1.54

chr15_-_25582891 1.54

chr1_+_16983775 1.53 ENSDART00000030665
slc25a4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr15_+_32853646 1.51 ENSDART00000167515
postnb
periostin, osteoblast specific factor b
chr3_+_1413640 1.51 ENSDART00000055430
ndufa6
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6
chr13_-_37001997 1.50 ENSDART00000135510
syne2b
spectrin repeat containing, nuclear envelope 2b
chr10_-_38206238 1.48 ENSDART00000174882
FP016248.1
ENSDARG00000107804
chr11_+_27970922 1.47 ENSDART00000169360
ENSDART00000043756
ephb2b
eph receptor B2b
chr13_-_31304614 1.47

chr1_-_20218263 1.46 ENSDART00000078271
cpe
carboxypeptidase E
chr23_-_15574072 1.45 ENSDART00000035865
ENSDART00000104904
sulf2b
sulfatase 2b
chr9_-_22461196 1.44 ENSDART00000135190
crygm2d7
crystallin, gamma M2d7
chr22_+_10728099 1.44 ENSDART00000145551
tmprss9
transmembrane protease, serine 9
chr6_-_40724581 1.42 ENSDART00000035101
kbtbd12
kelch repeat and BTB (POZ) domain containing 12
chr5_+_26840147 1.41 ENSDART00000064701
loxl2b
lysyl oxidase-like 2b
chr24_-_21778717 1.41 ENSDART00000131944
tagln3b
transgelin 3b
chr20_-_45819128 1.41 ENSDART00000124283
gpcpd1
glycerophosphocholine phosphodiesterase 1
chr10_+_6316944 1.41 ENSDART00000162428
tpm2
tropomyosin 2 (beta)
chr2_+_30932612 1.41 ENSDART00000132450
ENSDART00000137012
myom1a
myomesin 1a (skelemin)
chr11_+_30482530 1.40 ENSDART00000103270
slc22a7a
solute carrier family 22 (organic anion transporter), member 7a
chr3_+_47735048 1.40 ENSDART00000083024
gpr146
G protein-coupled receptor 146
chr14_-_14337584 1.38 ENSDART00000167119
ENSDART00000168027
ENSDART00000167521
znf185
zinc finger protein 185 with LIM domain
KN150642v1_+_9419 1.37 ENSDART00000159069
atoh1b
atonal bHLH transcription factor 1b
chr7_-_3900223 1.37 ENSDART00000019949
ndrg2
NDRG family member 2
chr11_-_29891067 1.36 ENSDART00000172106
scml2
sex comb on midleg-like 2 (Drosophila)
chr17_+_8874210 1.36

chr21_-_19789339 1.36

chr24_+_5205878 1.35 ENSDART00000106488
ENSDART00000005901
plod2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr20_-_17006936 1.34 ENSDART00000012859
psma6b
proteasome subunit alpha 6b
chr16_-_55320569 1.32 ENSDART00000156368
ENSDARG00000069583
ENSDARG00000069583
chr3_-_45779817 1.32 ENSDART00000164361
gcgra
glucagon receptor a
chr22_-_2870591 1.32 ENSDART00000063533
aqp12
aquaporin 12
chr5_-_70939686 1.32

chr19_-_5416317 1.31 ENSDART00000010373
krt1-19d
keratin, type 1, gene 19d
chr2_-_47578695 1.30 ENSDART00000014350
ENSDART00000038828
pax3a
paired box 3a
chr2_+_33399405 1.30 ENSDART00000137207
slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr13_+_14873339 1.30 ENSDART00000057810
emx1
empty spiracles homeobox 1
chr18_+_45893199 1.29 ENSDART00000158246
dvl3b
dishevelled segment polarity protein 3b
chr3_-_23444371 1.29 ENSDART00000087726
igf2bp1
insulin-like growth factor 2 mRNA binding protein 1
chr17_+_381715 1.29 ENSDART00000162898
si:rp71-62i8.1
si:rp71-62i8.1
chr24_-_12794672 1.28 ENSDART00000024084
pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr16_+_46145286 1.28 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr5_-_36647498 1.28 ENSDART00000112312
lrch2
leucine-rich repeats and calponin homology (CH) domain containing 2
chr12_+_35018663 1.28 ENSDART00000085774
si:ch73-127m5.1
si:ch73-127m5.1
chr14_+_35906366 1.27 ENSDART00000105602
elovl6
ELOVL fatty acid elongase 6
chr19_-_30816780 1.27 ENSDART00000103475
agr2
anterior gradient 2
chr5_+_3172101 1.27 ENSDART00000080486
ywhag1
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1
chr7_-_39170016 1.26 ENSDART00000161191
BX842701.1
ENSDARG00000101872
chr23_+_27985224 1.24 ENSDART00000171859
ENSDARG00000100606
ENSDARG00000100606
chr5_-_25866099 1.23 ENSDART00000144035
arvcfb
armadillo repeat gene deleted in velocardiofacial syndrome b
chr6_+_12618821 1.23 ENSDART00000156341
fam117ba
family with sequence similarity 117, member Ba
chr14_-_46359062 1.23 ENSDART00000090844
zgc:153018
zgc:153018
chr5_+_40722565 1.22 ENSDART00000097546
arid3c
AT rich interactive domain 3C (BRIGHT-like)
chr19_+_712139 1.20 ENSDART00000093281
fhod3a
formin homology 2 domain containing 3a
chr18_+_20504980 1.20 ENSDART00000060295
rapsn
receptor-associated protein of the synapse, 43kD
chr9_-_22488422 1.19 ENSDART00000124600
crygm2d21
crystallin, gamma M2d21
chr2_-_31319359 1.19 ENSDART00000060812
adcyap1b
adenylate cyclase activating polypeptide 1b
chr6_+_36965023 1.19 ENSDART00000028895
negr1
neuronal growth regulator 1
chr25_+_23494481 1.18 ENSDART00000089199
cpt1ab
carnitine palmitoyltransferase 1Ab (liver)
chr16_+_21436660 1.17 ENSDART00000145886
osbpl3b
oxysterol binding protein-like 3b
chr10_-_38206060 1.17 ENSDART00000174882
FP016248.1
ENSDARG00000107804
chr9_+_42112576 1.16 ENSDART00000130434
ENSDART00000007058
col18a1a
collagen type XVIII alpha 1 chain a
chr4_+_1750689 1.16 ENSDART00000146779
slc38a2
solute carrier family 38, member 2
chr18_-_48498261 1.15 ENSDART00000146346
kcnj1a.6
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6
chr3_-_18426055 1.15 ENSDART00000122968
aqp8b
aquaporin 8b
chr14_+_38375351 1.15 ENSDART00000175744
BX088707.3
ENSDARG00000107351
chr7_+_36267647 1.14 ENSDART00000173653
chd9
chromodomain helicase DNA binding protein 9
chr4_-_16344954 1.14 ENSDART00000079523
epyc
epiphycan
chr20_+_40247918 1.14 ENSDART00000121818
trdn
triadin
chr10_+_13251463 1.13 ENSDART00000000887
rassf6
Ras association (RalGDS/AF-6) domain family 6
chr15_+_27431469 1.12 ENSDART00000122101
tbx2b
T-box 2b
chr6_-_586251 1.12 ENSDART00000148867
ENSDART00000149414
ENSDART00000149248
lgals2b
lectin, galactoside-binding, soluble, 2b
chr7_+_25861386 1.11 ENSDART00000129834
nat16
N-acetyltransferase 16
chr24_+_16249188 1.11 ENSDART00000164516
sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr17_+_17935213 1.11 ENSDART00000104999
ccdc85ca
coiled-coil domain containing 85C, a
chr5_+_15167637 1.11 ENSDART00000127015
srrm4
serine/arginine repetitive matrix 4
chr15_-_2969420 1.10

chr18_+_9413588 1.10 ENSDART00000061886
sema3ab
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr1_-_48853800 1.09 ENSDART00000137357
zgc:175214
zgc:175214
chr16_+_1338291 1.09 ENSDART00000149299
cers2b
ceramide synthase 2b
chr21_-_3301751 1.09 ENSDART00000009740
smad7
SMAD family member 7
chr19_-_24859287 1.08 ENSDART00000163763
thbs3b
thrombospondin 3b
chr22_+_16511562 1.08

chr16_+_53238110 1.07 ENSDART00000102170
CABZ01053976.1
ENSDARG00000069929
chr7_-_33994315 1.07 ENSDART00000173596
si:ch211-98n17.5
si:ch211-98n17.5
chr17_+_16067769 1.07 ENSDART00000155292
si:ch73-204p21.2
si:ch73-204p21.2
chr13_+_22350043 1.06 ENSDART00000136863
ldb3a
LIM domain binding 3a
chr1_+_16681778 1.05

chr15_-_2689005 1.05 ENSDART00000063325
cldnf
claudin f
chr23_-_31446156 1.05 ENSDART00000053367
hmgn3
high mobility group nucleosomal binding domain 3
KN150683v1_+_13359 1.04

chr16_-_42968807 1.04 ENSDART00000154757
txnipb
thioredoxin interacting protein b
chr2_-_30675594 1.03 ENSDART00000087270
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr5_+_69383382 1.03 ENSDART00000165570
rgs3a
regulator of G protein signaling 3a
chr12_-_457997 1.02 ENSDART00000143232
dhrs7cb
dehydrogenase/reductase (SDR family) member 7Cb
chr20_-_11179880 1.02 ENSDART00000152246
flrt2
fibronectin leucine rich transmembrane protein 2
chr6_+_3549861 1.02 ENSDART00000170781
phospho2
phosphatase, orphan 2
chr6_+_44817077 1.01 ENSDART00000169713
chl1b
cell adhesion molecule L1-like b
chr7_-_2367001 1.01 ENSDART00000174011
si:cabz01007812.1
si:cabz01007812.1
chr18_+_36650892 1.00 ENSDART00000098980
znf296
zinc finger protein 296
chr6_-_49900124 1.00 ENSDART00000150204
atp5e
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
chr8_-_11512545 0.99 ENSDART00000133932
si:ch211-248e11.2
si:ch211-248e11.2
chr16_-_1479139 0.99 ENSDART00000036348
sim1a
single-minded family bHLH transcription factor 1a
chr19_-_9793494 0.99 ENSDART00000134816
slc2a3a
solute carrier family 2 (facilitated glucose transporter), member 3a
chr20_-_40217185 0.99

chr9_-_711269 0.98 ENSDART00000144625
ndufb3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3
chr23_+_18796386 0.98 ENSDART00000137438
myh7bb
myosin, heavy chain 7B, cardiac muscle, beta b
chr1_-_11591684 0.97 ENSDART00000003825
cplx2l
complexin 2, like
chr8_+_24725855 0.97 ENSDART00000078656
slc16a4
solute carrier family 16, member 4
chr4_-_25282256 0.97 ENSDART00000066936
tmem110l
transmembrane protein 110, like
chr25_-_22890657 0.97

chr2_+_52473102 0.96 ENSDART00000146418
shda
Src homology 2 domain containing transforming protein D, a
chr9_-_22377136 0.96 ENSDART00000110933
CR847505.1
ENSDARG00000076693
chr24_-_23829288 0.96 ENSDART00000080510
ENSDART00000135242
ENSDARG00000019332
ENSDARG00000019332
chr5_-_54150484 0.96 ENSDART00000058470
pik3r1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr5_-_63031745 0.96

chr6_+_48138737 0.95

chr10_+_34372205 0.95 ENSDART00000110121
stard13a
StAR-related lipid transfer (START) domain containing 13a
chr3_-_13942505 0.95

chr10_-_38206132 0.95 ENSDART00000174882
FP016248.1
ENSDARG00000107804
chr8_-_2447758 0.95 ENSDART00000101125
rpl6
ribosomal protein L6
chr9_+_21725007 0.95 ENSDART00000045093
arhgef7a
Rho guanine nucleotide exchange factor (GEF) 7a
chr14_-_6822151 0.95 ENSDART00000171311
si:ch73-43g23.1
si:ch73-43g23.1
chr23_-_3760604 0.95 ENSDART00000143731
pacsin1a
protein kinase C and casein kinase substrate in neurons 1a
chr18_-_11439124 0.95

chr11_-_33925792 0.95 ENSDART00000172978
atp13a3
ATPase type 13A3
chr8_-_49443058 0.94 ENSDART00000011453
sypb
synaptophysin b
chr8_+_23192085 0.94 ENSDART00000032996
ENSDART00000137536
ppdpfa
pancreatic progenitor cell differentiation and proliferation factor a
chr25_-_33920256 0.94

chr14_-_48951428 0.93 ENSDART00000157785
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr7_+_24770873 0.92 ENSDART00000165314
AL954715.1
ENSDARG00000103682
chr8_+_48624273 0.92 ENSDART00000121432
nppa
natriuretic peptide A
chr7_+_28862183 0.92 ENSDART00000052346
gnao1b
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b
chr25_+_35901081 0.92 ENSDART00000042271
ENSDART00000158027
irx3b
iroquois homeobox 3b
chr5_-_43896815 0.92 ENSDART00000110076
gas1a
growth arrest-specific 1a
chr11_-_6004509 0.92 ENSDART00000108628
ano8b
anoctamin 8b
chr5_-_31301280 0.92 ENSDART00000141446
coro1cb
coronin, actin binding protein, 1Cb
chr6_+_1895734 0.91 ENSDART00000109679
quo
quattro
chr20_+_3095763 0.91 ENSDART00000133435
CEP170B
centrosomal protein 170B
chr16_-_17439735 0.91 ENSDART00000144392
zyx
zyxin
chr6_-_39608334 0.91 ENSDART00000179059
dip2bb
disco-interacting protein 2 homolog Bb
chr13_-_39821399 0.91 ENSDART00000056996
sfrp5
secreted frizzled-related protein 5

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:1905178 regulation of cardiac muscle tissue regeneration(GO:1905178)
1.2 4.8 GO:0071549 propionate metabolic process(GO:0019541) propionate catabolic process(GO:0019543) glycerol biosynthetic process from pyruvate(GO:0046327) cellular response to dexamethasone stimulus(GO:0071549)
1.1 4.5 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.9 2.8 GO:0072578 neurotransmitter-gated ion channel clustering(GO:0072578)
0.7 2.1 GO:0014819 regulation of skeletal muscle contraction(GO:0014819) positive regulation of muscle contraction(GO:0045933)
0.7 3.3 GO:0035777 pronephric distal tubule development(GO:0035777)
0.6 3.6 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.6 1.8 GO:0032369 negative regulation of lipid transport(GO:0032369)
0.5 1.0 GO:0071331 cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.5 1.4 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.5 1.4 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.4 1.7 GO:0015859 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.4 2.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.4 2.3 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.3 1.4 GO:0048664 auditory receptor cell fate commitment(GO:0009912) neuron fate determination(GO:0048664) inner ear receptor cell fate commitment(GO:0060120)
0.3 1.0 GO:0035776 pronephric proximal tubule development(GO:0035776)
0.3 1.3 GO:0099565 chemical synaptic transmission, postsynaptic(GO:0099565)
0.3 0.9 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
0.3 2.0 GO:0072132 mesenchyme morphogenesis(GO:0072132)
0.3 1.4 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.3 3.7 GO:0016203 muscle attachment(GO:0016203)
0.3 0.8 GO:0009957 epidermal cell fate specification(GO:0009957)
0.3 2.2 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.3 1.5 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.3 1.3 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.2 1.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 0.9 GO:0003085 negative regulation of systemic arterial blood pressure(GO:0003085)
0.2 3.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 0.6 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.2 1.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.2 1.3 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.2 0.8 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.2 1.3 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.2 0.7 GO:0061036 positive regulation of chondrocyte differentiation(GO:0032332) positive regulation of cartilage development(GO:0061036)
0.2 0.5 GO:1900116 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of BMP from receptor via BMP binding(GO:0038098) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2 12.1 GO:0007601 visual perception(GO:0007601)
0.2 1.9 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.2 1.7 GO:0016540 protein autoprocessing(GO:0016540)
0.2 1.0 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591)
0.2 0.5 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.2 0.5 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 1.2 GO:0006868 glutamine transport(GO:0006868)
0.2 1.3 GO:0050936 xanthophore differentiation(GO:0050936)
0.2 0.8 GO:0010991 SMAD protein complex assembly(GO:0007183) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.2 0.6 GO:0072314 visceral serous pericardium development(GO:0061032) glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.2 0.8 GO:0032264 IMP salvage(GO:0032264)
0.2 0.5 GO:0052805 imidazole-containing compound metabolic process(GO:0052803) imidazole-containing compound catabolic process(GO:0052805)
0.1 0.4 GO:0061114 pancreas morphogenesis(GO:0061113) branching involved in pancreas morphogenesis(GO:0061114) pancreatic bud formation(GO:0061130) pancreas field specification(GO:0061131)
0.1 0.4 GO:0042756 drinking behavior(GO:0042756)
0.1 0.4 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.6 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 0.7 GO:0032309 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 1.1 GO:0042551 neuron maturation(GO:0042551)
0.1 0.4 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.7 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.1 1.7 GO:0097320 membrane tubulation(GO:0097320)
0.1 2.1 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 1.4 GO:0046037 GMP biosynthetic process(GO:0006177) GTP biosynthetic process(GO:0006183) GMP metabolic process(GO:0046037)
0.1 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 1.2 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.6 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.9 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 0.7 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.1 0.8 GO:0090303 positive regulation of wound healing(GO:0090303)
0.1 0.2 GO:0045117 azole transport(GO:0045117)
0.1 0.9 GO:0034389 lipid particle organization(GO:0034389)
0.1 1.6 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 1.4 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 0.8 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.1 0.3 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.8 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.1 0.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.9 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 1.9 GO:0001966 thigmotaxis(GO:0001966)
0.1 1.5 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.1 0.3 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.1 1.0 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.3 GO:0048070 regulation of developmental pigmentation(GO:0048070)
0.1 1.0 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 0.3 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.1 0.7 GO:2000251 regulation of actin cytoskeleton reorganization(GO:2000249) positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 1.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 1.7 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.5 GO:0016572 histone phosphorylation(GO:0016572)
0.1 1.3 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 0.5 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.1 1.5 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.1 0.4 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 1.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 1.8 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 1.8 GO:0045214 sarcomere organization(GO:0045214)
0.1 0.8 GO:0061099 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 5.4 GO:0006936 muscle contraction(GO:0006936)
0.1 0.6 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.1 0.4 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 4.1 GO:0071560 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.1 1.4 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 1.7 GO:0043049 otic placode formation(GO:0043049)
0.1 0.4 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.8 GO:0007416 synapse assembly(GO:0007416)
0.0 0.4 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.8 GO:0050773 regulation of dendrite development(GO:0050773)
0.0 0.1 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.2 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 1.0 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 0.4 GO:0006188 IMP biosynthetic process(GO:0006188)
0.0 0.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 3.3 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.6 GO:0045332 phospholipid translocation(GO:0045332)
0.0 2.0 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 1.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.9 GO:0016114 terpenoid biosynthetic process(GO:0016114)
0.0 0.4 GO:0006956 complement activation(GO:0006956)
0.0 0.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.5 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.0 0.9 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 1.4 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.3 GO:0031033 myosin filament organization(GO:0031033)
0.0 1.4 GO:0031638 zymogen activation(GO:0031638)
0.0 1.6 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 1.0 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.2 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 1.5 GO:0001817 regulation of cytokine production(GO:0001817)
0.0 1.4 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.5 GO:0006825 copper ion transport(GO:0006825)
0.0 1.3 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.6 GO:0046460 triglyceride biosynthetic process(GO:0019432) neutral lipid biosynthetic process(GO:0046460) acylglycerol biosynthetic process(GO:0046463)
0.0 0.1 GO:0043627 response to estrogen(GO:0043627)
0.0 1.3 GO:0045010 actin nucleation(GO:0045010)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.7 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.0 3.0 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.4 GO:1902667 regulation of axon guidance(GO:1902667)
0.0 1.2 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.8 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 1.2 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.4 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 0.5 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.4 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 1.1 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.1 GO:0044209 purine nucleotide salvage(GO:0032261) AMP salvage(GO:0044209)
0.0 1.4 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 0.1 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.3 GO:0043409 negative regulation of MAPK cascade(GO:0043409)
0.0 0.7 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.1 GO:0051031 tRNA transport(GO:0051031)
0.0 0.2 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.2 GO:0060840 artery development(GO:0060840)
0.0 2.7 GO:0007517 muscle organ development(GO:0007517)
0.0 0.5 GO:0009142 nucleoside triphosphate biosynthetic process(GO:0009142)
0.0 0.3 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 0.3 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.0 0.2 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 1.0 GO:0003407 neural retina development(GO:0003407)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0036010 protein localization to endosome(GO:0036010) protein localization to early endosome(GO:1902946)
0.0 0.4 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.9 GO:0031430 M band(GO:0031430)
0.4 2.1 GO:0048179 activin receptor complex(GO:0048179)
0.3 3.5 GO:0030667 secretory granule membrane(GO:0030667)
0.3 5.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 2.2 GO:0016011 dystroglycan complex(GO:0016011)
0.2 1.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 2.9 GO:0043195 terminal bouton(GO:0043195)
0.2 0.3 GO:0042583 chromaffin granule(GO:0042583)
0.2 2.5 GO:0031594 neuromuscular junction(GO:0031594)
0.2 1.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 1.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 2.0 GO:0005869 dynactin complex(GO:0005869)
0.2 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 5.0 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 1.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 1.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 1.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 6.4 GO:0005882 intermediate filament(GO:0005882)
0.1 0.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 2.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 2.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 1.8 GO:0016342 catenin complex(GO:0016342)
0.1 2.3 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 0.2 GO:0071914 prominosome(GO:0071914)
0.1 1.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 2.6 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 1.4 GO:0043204 perikaryon(GO:0043204)
0.0 2.7 GO:0005581 collagen trimer(GO:0005581)
0.0 1.7 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 24.9 GO:0005615 extracellular space(GO:0005615)
0.0 3.1 GO:0005884 actin filament(GO:0005884)
0.0 0.3 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.4 GO:0016459 myosin complex(GO:0016459)
0.0 3.9 GO:0005912 adherens junction(GO:0005912)
0.0 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.3 GO:0030125 clathrin vesicle coat(GO:0030125) clathrin-coated vesicle membrane(GO:0030665)
0.0 0.4 GO:0008305 integrin complex(GO:0008305)
0.0 0.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.2 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 5.9 GO:0005576 extracellular region(GO:0005576)
0.0 0.7 GO:0016605 PML body(GO:0016605)
0.0 1.1 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.0 1.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.0 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.6 GO:0030027 lamellipodium(GO:0030027)
0.0 1.2 GO:0015629 actin cytoskeleton(GO:0015629)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.8 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.7 7.0 GO:0005113 patched binding(GO:0005113)
0.5 2.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.5 1.9 GO:0016936 galactoside binding(GO:0016936)
0.5 1.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.4 1.7 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.4 1.7 GO:0033971 hydroxyisourate hydrolase activity(GO:0033971)
0.4 12.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.4 2.3 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.4 1.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.4 3.6 GO:0004017 adenylate kinase activity(GO:0004017)
0.3 1.4 GO:0016521 pituitary adenylate cyclase activating polypeptide activity(GO:0016521)
0.3 0.7 GO:2001070 starch binding(GO:2001070)
0.3 2.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.3 2.2 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.3 1.5 GO:0019841 retinol binding(GO:0019841)
0.2 0.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 3.3 GO:0015245 long-chain fatty acid transporter activity(GO:0005324) fatty acid transporter activity(GO:0015245)
0.2 1.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 1.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 0.7 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.2 1.8 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.2 0.6 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.2 1.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 0.8 GO:0070412 R-SMAD binding(GO:0070412)
0.2 1.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.2 1.2 GO:0015250 water channel activity(GO:0015250)
0.2 2.4 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.6 GO:0016531 copper chaperone activity(GO:0016531)
0.2 1.2 GO:0043495 protein anchor(GO:0043495)
0.2 2.2 GO:0043236 laminin binding(GO:0043236)
0.2 0.7 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.2 0.8 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 1.8 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 0.8 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 1.8 GO:0017046 peptide hormone binding(GO:0017046)
0.1 1.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.8 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 1.8 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 3.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 1.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 1.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.4 GO:0070699 beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
0.1 0.2 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1 2.2 GO:0030371 translation repressor activity(GO:0030371)
0.1 1.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.9 GO:0031852 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.4 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.7 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.1 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.5 GO:0036122 BMP binding(GO:0036122)
0.1 0.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.3 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.4 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 0.5 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 1.1 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.7 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 1.6 GO:0051427 hormone receptor binding(GO:0051427)
0.1 4.4 GO:0045296 cadherin binding(GO:0045296)
0.1 0.4 GO:0031704 apelin receptor binding(GO:0031704)
0.1 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.4 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.1 0.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.7 GO:0016405 CoA-ligase activity(GO:0016405)
0.1 0.5 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.4 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.2 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 1.1 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.8 GO:0016722 oxidoreductase activity, oxidizing metal ions(GO:0016722)
0.1 2.2 GO:0019905 syntaxin binding(GO:0019905)
0.1 1.1 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.4 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 1.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 3.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.1 GO:0005267 potassium channel activity(GO:0005267)
0.1 0.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 1.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.5 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 2.7 GO:0008201 heparin binding(GO:0008201)
0.0 11.6 GO:0051015 actin filament binding(GO:0051015)
0.0 0.8 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.4 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 1.4 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 1.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 2.3 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0019201 nucleotide kinase activity(GO:0019201)
0.0 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 1.0 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.6 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.8 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 1.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 1.4 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 3.7 GO:0003779 actin binding(GO:0003779)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.4 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.0 GO:0015293 symporter activity(GO:0015293)
0.0 12.1 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.2 2.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.2 2.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 1.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 5.3 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.1 PID ALK1 PATHWAY ALK1 signaling events
0.1 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.9 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 1.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 2.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 2.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.3 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.3 1.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 3.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 4.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.2 1.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 1.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.8 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 0.9 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.8 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 0.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 0.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 2.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.7 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 3.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 0.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.7 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.8 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 2.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases