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Results for esrrb_esrra+esrrgb_esrrd+esrrga

Z-value: 1.59

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Transcription factors associated with esrrb_esrra+esrrgb_esrrd+esrrga

Gene Symbol Gene ID Gene Info
ENSDARG00000100847 estrogen-related receptor beta
ENSDARG00000011696 estrogen-related receptor gamma b
ENSDARG00000069266 estrogen-related receptor alpha
ENSDARG00000004861 estrogen-related receptor gamma a
ENSDARG00000015064 estrogen-related receptor delta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
esrrddr10_dc_chr18_-_48996702_489967080.439.3e-02Click!
esrradr10_dc_chr21_+_26569956_26570073-0.087.6e-01Click!
esrrgadr10_dc_chr17_-_29885237_298852920.058.4e-01Click!

Activity profile of esrrb_esrra+esrrgb_esrrd+esrrga motif

Sorted Z-values of esrrb_esrra+esrrgb_esrrd+esrrga motif

Network of associatons between targets according to the STRING database.

First level regulatory network of esrrb_esrra+esrrgb_esrrd+esrrga

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_-_5186692 2.61 ENSDART00000037007
triosephosphate isomerase 1a
chr15_-_23711689 2.55 ENSDART00000128644
creatine kinase, muscle b
chr5_-_37285874 2.42 ENSDART00000132152
si:ch211-139a5.9
chr21_+_4916179 2.24 ENSDART00000024199
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
KN150214v1_-_155944 2.21

chr8_-_22265875 1.97 ENSDART00000134033
si:ch211-147a11.3
chr2_+_42342148 1.91 ENSDART00000144716
caveolae associated protein 4a
chr23_+_44795356 1.89 ENSDART00000145905
enolase 3, (beta, muscle)
chr12_-_457997 1.80 ENSDART00000143232
dehydrogenase/reductase (SDR family) member 7Cb
chr13_+_30441704 1.78 ENSDART00000010052
peptidylprolyl isomerase Fa
chr2_+_30932612 1.71 ENSDART00000132450
ENSDART00000137012
myomesin 1a (skelemin)
chr14_-_17270022 1.66 ENSDART00000123145
ring finger protein 4
chr8_+_39726489 1.65 ENSDART00000037914
cytochrome c oxidase subunit VIa polypeptide 1
chr17_-_12231165 1.63 ENSDART00000080927
synaptosomal-associated protein, 25b
chr12_-_25110065 1.60 ENSDART00000077188
cytochrome c oxidase subunit VIIa polypeptide 3
chr3_-_21149752 1.59 ENSDART00000003939
synaptogyrin 1a
chr20_-_16271651 1.58 ENSDART00000012476
cytochrome c oxidase assembly factor 7
chr7_+_22027602 1.57 ENSDART00000056790
transmembrane protein 256
chr10_-_36747849 1.56 ENSDART00000122375
mitochondrial ribosomal protein L48
chr2_-_42729754 1.54 ENSDART00000025997
disco-interacting protein 2 homolog Cb
chr11_-_7310284 1.54 ENSDART00000091664
adenomatosis polyposis coli 2
chr16_-_50024848 1.53 ENSDART00000161782
electron-transfer-flavoprotein, beta polypeptide
chr6_+_52235389 1.46 ENSDART00000056319
cytochrome c oxidase subunit VIc
chr16_+_11833310 1.42 ENSDART00000060266
carcinoembryonic antigen-related cell adhesion molecule 1
chr24_-_23829288 1.41 ENSDART00000080510
ENSDART00000135242
ENSDARG00000019332
chr8_+_7237516 1.34

chr1_-_54570813 1.34 ENSDART00000098615
nanos homolog 3
chr5_-_36503296 1.30 ENSDART00000149211
interleukin 13 receptor, alpha 2
chr21_-_25379720 1.27 ENSDART00000114081
ENSDART00000161629
spermine synthase
chr7_+_51499409 1.26 ENSDART00000007767
glutamic-oxaloacetic transaminase 2b, mitochondrial
chr1_-_54041101 1.23 ENSDART00000122601
phosphoglycerate mutase 1b
chr19_-_1376498 1.20 ENSDART00000158429
transmembrane protein 42b
chr3_+_58096720 1.20 ENSDART00000010395
ENSDART00000159755
ENSDART00000171149
ubiquinol-cytochrome c reductase core protein IIa
chr6_-_10600358 1.20 ENSDART00000135065
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c3 (subunit 9) b
chr13_+_42276937 1.19

chr6_-_15526547 1.19 ENSDART00000038133
tripartite motif containing 63a
chr17_+_23534824 1.17 ENSDART00000135814
pantothenate kinase 1a
chr3_-_32205873 1.17 ENSDART00000156918
si:dkey-16p21.8
chr20_+_230164 1.16 ENSDART00000002661
laminin, alpha 4
chr21_-_19789339 1.16

chr12_+_22551105 1.15 ENSDART00000123808
ENSDART00000159864
cell division cycle associated 9
chr21_+_37726304 1.15 ENSDART00000076320
mitochondrial ribosomal protein S17
chr17_-_26592356 1.14 ENSDART00000016608
mitochondrial ribosomal protein L57
chr16_+_5697911 1.09 ENSDART00000017307
zgc:91890
chr17_-_1907622 1.08 ENSDART00000156489
x globin
chr14_-_33114322 1.08 ENSDART00000173267
transmembrane protein 255A
chr16_-_17289585 1.07 ENSDART00000135146
glyceraldehyde-3-phosphate dehydrogenase
chr2_-_5034234 1.06 ENSDART00000165296
transferrin receptor 1a
chr5_+_1223598 1.03 ENSDART00000159783
ENSDART00000026535
ENSDART00000168130
ENSDART00000147972
dynamin 1a
chr1_-_42915971 1.03

chr21_+_5775383 1.03 ENSDART00000165065
ubiquinol-cytochrome c reductase, complex III subunit X
chr23_-_27123433 1.03 ENSDART00000142324
ENSDART00000133249
ENSDARG00000025766
chr12_-_25110150 1.02 ENSDART00000077188
cytochrome c oxidase subunit VIIa polypeptide 3
chr6_-_33893933 0.99 ENSDART00000129916
transmembrane protein 69
chr13_-_37144297 0.99

chr21_+_15608551 0.98 ENSDART00000024858
coiled-coil-helix-coiled-coil-helix domain containing 10
chr16_-_22903823 0.97

chr1_-_16876855 0.97 ENSDART00000125125
acyl-CoA synthetase long-chain family member 1a
chr14_-_29487265 0.96

chr13_+_15669924 0.96 ENSDART00000146234
apoptogenic 1, mitochondrial
chr22_-_10324166 0.95 ENSDART00000092050
stabilin 1
chr3_-_49031058 0.95 ENSDART00000154561
mitochondrial ribosomal protein L12
chr17_-_1907667 0.94 ENSDART00000156489
x globin
chr14_-_35552296 0.94 ENSDART00000052648
transmembrane protein 144b
chr13_+_7055611 0.93 ENSDART00000148240
exocyst complex component 3-like 4
chr22_-_11106940 0.93 ENSDART00000016873
ATPase, H+ transporting, lysosomal accessory protein 2
chr12_+_44829938 0.93 ENSDART00000098932
WW domain binding protein 2
chr22_+_2237813 0.93

chr6_-_39767452 0.92 ENSDART00000085277
phosphofructokinase, muscle b
chr14_+_35074248 0.92 ENSDART00000084914
tRNA methyltransferase 12 homolog (S. cerevisiae)
chr12_+_20569459 0.90 ENSDART00000112847
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1, tandem duplicate 2
chr11_-_34521855 0.90 ENSDART00000039847
ENSDART00000135725
coiled-coil-helix-coiled-coil-helix domain containing 4a
chr7_-_57941497 0.90 ENSDART00000114008
un-named hu7910
chr3_-_34006846 0.89 ENSDART00000136900
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr23_-_20026717 0.89 ENSDART00000153828
ATPase, Ca++ transporting, plasma membrane 3b
chr24_-_20496410 0.88 ENSDART00000166135
zinc finger and BTB domain containing 47b
chr11_+_24874769 0.87 ENSDART00000147546
ndrg family member 3a
chr2_+_34155114 0.87 ENSDART00000137170
aspartyl-tRNA synthetase 2, mitochondrial
chr7_-_39170016 0.87 ENSDART00000161191
ENSDARG00000101872
chr18_+_16755239 0.87 ENSDART00000133490
lymphatic vessel endothelial hyaluronic receptor 1b
chr19_-_32900108 0.85 ENSDART00000050130
guanosine monophosphate reductase
chr9_-_21257082 0.85 ENSDART00000124533
T-box 15
chr5_-_33359649 0.84 ENSDART00000143652
zgc:63972
chr20_+_37891795 0.84 ENSDART00000022060
activating transcription factor 3
chr20_+_37891739 0.81 ENSDART00000022060
activating transcription factor 3
chr20_+_35183036 0.81 ENSDART00000114262
CDC42 binding protein kinase alpha (DMPK-like) b
chr13_+_30441803 0.81 ENSDART00000144417
peptidylprolyl isomerase Fa
chr19_+_21140010 0.81 ENSDART00000090757
K(lysine) acetyltransferase 2B
chr8_-_14014576 0.80 ENSDART00000135811
ATPase, Ca++ transporting, plasma membrane 3a
chr8_+_7625846 0.79 ENSDART00000175045
ENSDARG00000107577
chr13_+_50062513 0.79 ENSDART00000124142
ENSDART00000099537
cytochrome c oxidase subunit Vb 2
chr2_+_55859099 0.79 ENSDART00000097753
ENSDART00000141688
nicotinamide riboside kinase 2
chr4_+_8007952 0.78 ENSDART00000014036
optineurin
chr16_-_45269179 0.78 ENSDART00000162095
si:dkey-33i11.4
chr2_-_47612319 0.77 ENSDART00000133615
ENSDARG00000091979
chr18_+_20504980 0.77 ENSDART00000060295
receptor-associated protein of the synapse, 43kD
chr8_+_7625791 0.77 ENSDART00000175045
ENSDARG00000107577
chr1_+_15880988 0.75 ENSDART00000166317
microtubule associated tumor suppressor 1b
chr24_-_20496308 0.75 ENSDART00000166135
zinc finger and BTB domain containing 47b
chr18_+_30529524 0.74 ENSDART00000026866
cytochrome c oxidase subunit IV isoform 1
chr21_-_37886693 0.73 ENSDART00000177664
ENSDARG00000108937
chr7_-_57727148 0.72

chr21_+_27477153 0.72 ENSDART00000065420
phosphofurin acidic cluster sorting protein 1a
chr6_+_29412348 0.71 ENSDART00000104298
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 5
chr2_+_30266427 0.70 ENSDART00000135171
transmembrane protein 70
chr20_-_16271738 0.69 ENSDART00000012476
cytochrome c oxidase assembly factor 7
chr21_-_44109455 0.69 ENSDART00000044599
organic anion transporter X
chr7_+_22027528 0.68 ENSDART00000056790
transmembrane protein 256
chr3_-_52644257 0.68 ENSDART00000128223
coiled-coil-helix-coiled-coil-helix domain containing 5
chr16_-_5821719 0.68 ENSDART00000136655
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3
chr21_-_20344734 0.67 ENSDART00000115236
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit Ea
chr21_+_37760978 0.66 ENSDART00000145828
phosphoglycerate kinase 1
chr13_-_8979137 0.66 ENSDART00000058056
mitochondrial ribosomal protein S26
chr3_-_18426055 0.65 ENSDART00000122968
aquaporin 8b
chr17_-_38940072 0.65 ENSDART00000141177
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4a
chr7_+_52477995 0.65 ENSDART00000053814
mitochondrial methionyl-tRNA formyltransferase
chr20_-_10500595 0.65 ENSDART00000064112
glutaredoxin 5 homolog (S. cerevisiae)
chr3_-_21149711 0.64 ENSDART00000003939
synaptogyrin 1a
chr6_-_10086031 0.64

chr17_-_45140696 0.64

chr14_-_47125993 0.63 ENSDART00000124925
si:ch211-235e9.8
chr7_+_60091631 0.63 ENSDART00000121545
breast cancer metastasis suppressor 1
chr22_+_25755073 0.63 ENSDART00000174421
ENSDARG00000106684
chr7_-_48532462 0.63 ENSDART00000015884
milk fat globule-EGF factor 8 protein a
chr15_-_21756778 0.63 ENSDART00000039865
succinate dehydrogenase complex, subunit D, integral membrane protein b
chr2_-_23003738 0.63 ENSDART00000115025
THAP domain containing 4
chr2_+_7054686 0.62 ENSDART00000057385
nitric oxide synthase 1 (neuronal) adaptor protein b
chr17_+_33388313 0.61 ENSDART00000077553
xanthine dehydrogenase
chr2_+_1825714 0.61 ENSDART00000148624
HIG1 hypoxia inducible domain family, member 1A
chr7_+_48025010 0.61 ENSDART00000052123
solute carrier family 25, member 44 b
chr19_-_9793494 0.60 ENSDART00000134816
solute carrier family 2 (facilitated glucose transporter), member 3a
chr10_+_41237437 0.60 ENSDART00000141657
annexin A4
chr3_+_42217236 0.60 ENSDART00000168228
transmembrane protein 184a
chr15_-_16137131 0.60

chr11_-_22200590 0.60 ENSDART00000006580
transcription factor EB
chr14_-_33114284 0.59 ENSDART00000109615
transmembrane protein 255A
chr22_+_24112851 0.59

chr3_+_26015378 0.59

chr19_+_20579471 0.58 ENSDART00000090942
coiled-coil domain containing 126
chr2_-_55879949 0.58 ENSDART00000140309
complexin 4c
chr25_+_7858886 0.57 ENSDART00000171904
upper zone of growth plate and cartilage matrix associated b
chr10_+_9576840 0.57 ENSDART00000080843
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8
chr5_+_36374081 0.57 ENSDART00000040537
gap junction protein delta 1a
chr15_+_30246345 0.56 ENSDART00000100214
nuclear fragile X mental retardation protein interacting protein 2
chr16_+_13795468 0.56 ENSDART00000142428
Josephin domain containing 2
chr3_-_25246374 0.55 ENSDART00000077538
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr14_+_1226767 0.54 ENSDART00000127477
adenosine deaminase domain containing 1 (testis-specific)
chr6_-_54172509 0.53 ENSDART00000149468
ribosomal protein S10
chr11_-_80746 0.53

chr25_+_29873412 0.52 ENSDART00000067056
TopBP1-interacting, checkpoint, and replication regulator
chr5_-_54773058 0.52 ENSDART00000145791
prune homolog 2 (Drosophila)
chr25_-_34634503 0.52 ENSDART00000157370
Histone H3.2
chr10_-_43826919 0.52 ENSDART00000039551
ENSDART00000160786
ENSDART00000099134
myocyte enhancer factor 2ca
chr12_-_43939028 0.52 ENSDART00000170723
zgc:112964
chr8_+_39726564 0.52 ENSDART00000145112
cytochrome c oxidase subunit VIa polypeptide 1
chr25_+_35798656 0.51 ENSDART00000103006
zgc:110434
chr13_-_4720227 0.51 ENSDART00000165259
mitochondrial calcium uniporter
chr23_+_19271879 0.51 ENSDART00000047015
coiled-coil domain containing 115
chr15_+_20054306 0.51 ENSDART00000155199
zgc:112083
chr3_-_6633512 0.51 ENSDART00000165273
golgi associated, gamma adaptin ear containing, ARF binding protein 3
chr11_-_18081944 0.50 ENSDART00000113468
ENSDARG00000079534
chr4_-_22509152 0.50 ENSDART00000176950
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr24_+_37388311 0.50 ENSDART00000161181
si:dkey-224b4.1
chr6_+_9717087 0.50 ENSDART00000019325
cytochrome P450, family 20, subfamily A, polypeptide 1
chr7_+_29907542 0.50 ENSDART00000174420
ENSDARG00000008491
chr6_-_40065822 0.49 ENSDART00000157119
coiled-coil-helix-coiled-coil-helix domain containing 4b
chr20_+_45585743 0.49

chr20_-_2708931 0.49 ENSDART00000152120
akirin 2
chr18_+_41323776 0.49 ENSDART00000048985
ventricular zone expressed PH domain-containing 1
chr3_-_44414357 0.48 ENSDART00000160370
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
chr8_+_52544578 0.48 ENSDART00000127729
STAM binding protein b
chr7_-_24119717 0.48 ENSDART00000036680
prostaglandin reductase 1
chr13_+_40208832 0.48 ENSDART00000074950
solute carrier family 25 (mitochondrial iron transporter), member 28
chr18_-_48498261 0.47 ENSDART00000146346
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6
chr25_-_28636834 0.47 ENSDART00000138087
cytochrome c oxidase subunit Vaa
chr3_-_16056593 0.46

chr1_+_11661380 0.46 ENSDART00000144475
clathrin, light chain A
chr25_+_21079666 0.46 ENSDART00000149142
ELKS/RAB6-interacting/CAST family member 1a
chr17_-_50899135 0.46

chr4_-_1346961 0.46 ENSDART00000164623
pleiotrophin
chr9_+_55778669 0.45

chr8_-_22266041 0.45 ENSDART00000134033
si:ch211-147a11.3
chr10_+_9576710 0.45 ENSDART00000080843
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8
chr24_-_33817169 0.45 ENSDART00000079292
caveolae associated protein 4b
chr11_+_11217547 0.44 ENSDART00000087105
myomesin 2a
chr5_+_62585944 0.44

chr6_+_23476669 0.44

chr7_+_9659464 0.44 ENSDART00000172824
ceramide synthase 3a
chr15_-_9655500 0.44 ENSDART00000171214
ENSDART00000171911
asparaginyl-tRNA synthetase 2, mitochondrial (putative)
chr21_+_11792666 0.43 ENSDART00000092015
DDB1 and CUL4 associated factor 12
chr24_-_37810565 0.43 ENSDART00000172178
si:ch211-231f6.6
chr3_-_19750156 0.43 ENSDART00000134969
Rho family GTPase 2
chr7_-_28278230 0.43 ENSDART00000054368
suppression of tumorigenicity 5
chr12_-_3903961 0.43 ENSDART00000134292
ENSDARG00000021154
chr16_-_35474091 0.43 ENSDART00000172294
ENSDART00000162733
CTP synthase 1b
chr2_-_45118469 0.43 ENSDART00000018818
mitochondrial E3 ubiquitin protein ligase 1a
chr13_+_15669704 0.42 ENSDART00000146234
apoptogenic 1, mitochondrial
chr5_+_26804676 0.42 ENSDART00000121886
ENSDART00000005025
hematopoietic death receptor
chr7_+_38444768 0.42 ENSDART00000024590
synaptotagmin XIII
chr20_+_35182783 0.42 ENSDART00000040456
CDC42 binding protein kinase alpha (DMPK-like) b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.5 1.9 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.5 1.4 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.5 4.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.4 1.1 GO:0006531 aspartate metabolic process(GO:0006531)
0.3 1.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.3 2.4 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.3 0.9 GO:0042264 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.3 0.8 GO:1903010 regulation of bone development(GO:1903010)
0.3 1.3 GO:0033572 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.2 1.0 GO:1901490 regulation of lymphangiogenesis(GO:1901490) positive regulation of lymphangiogenesis(GO:1901492)
0.2 0.7 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 2.3 GO:0015671 oxygen transport(GO:0015671)
0.2 1.0 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.2 0.6 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.2 0.7 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.2 0.5 GO:0046887 positive regulation of peptide secretion(GO:0002793) positive regulation of insulin secretion(GO:0032024) positive regulation of hormone secretion(GO:0046887) positive regulation of peptide hormone secretion(GO:0090277)
0.2 0.5 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 0.7 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.2 1.1 GO:0061621 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 0.5 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.2 0.6 GO:0048790 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.2 0.9 GO:0051601 exocyst localization(GO:0051601)
0.2 1.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.1 1.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.4 GO:0098751 bone cell development(GO:0098751)
0.1 0.5 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.1 0.9 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.9 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 0.9 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 3.4 GO:0006119 oxidative phosphorylation(GO:0006119)
0.1 0.3 GO:0050886 sleep(GO:0030431) endocrine process(GO:0050886)
0.1 0.5 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 1.1 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.1 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 1.3 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.1 1.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.4 GO:0010481 keratinocyte development(GO:0003334) epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 2.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.1 GO:0070831 basement membrane assembly(GO:0070831)
0.1 0.3 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.1 0.3 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.1 0.4 GO:0060394 SMAD protein complex assembly(GO:0007183) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.5 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 0.4 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.8 GO:0033292 T-tubule organization(GO:0033292)
0.1 0.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.3 GO:0030730 regulation of sequestering of triglyceride(GO:0010889) positive regulation of sequestering of triglyceride(GO:0010890) sequestering of triglyceride(GO:0030730)
0.1 0.3 GO:0009223 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1 0.3 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1 0.3 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.6 GO:0046113 nucleobase catabolic process(GO:0046113)
0.1 1.3 GO:0019827 stem cell population maintenance(GO:0019827)
0.1 1.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 0.4 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.1 0.7 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.1 0.4 GO:0071450 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 1.0 GO:0051180 vitamin transport(GO:0051180)
0.1 0.9 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.9 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.6 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.4 GO:0019856 pyrimidine nucleobase metabolic process(GO:0006206) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 1.5 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 1.0 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 2.3 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.1 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 0.2 GO:0022602 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698)
0.0 0.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0071280 cellular response to copper ion(GO:0071280)
0.0 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.2 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.6 GO:0006825 copper ion transport(GO:0006825)
0.0 1.3 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0002446 neutrophil mediated immunity(GO:0002446) defense response to fungus(GO:0050832)
0.0 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.6 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 1.7 GO:0009615 response to virus(GO:0009615)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0061337 cardiac conduction(GO:0061337)
0.0 1.3 GO:0007416 synapse assembly(GO:0007416)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.6 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.5 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.1 GO:0002762 negative regulation of myeloid leukocyte differentiation(GO:0002762)
0.0 0.1 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.8 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.1 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 1.5 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.1 GO:0034340 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.8 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 2.2 GO:0006936 muscle contraction(GO:0006936)
0.0 0.3 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.0 0.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 1.1 GO:0018198 peptidyl-cysteine modification(GO:0018198)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.8 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 2.6 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.2 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 1.5 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.3 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0006692 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.1 GO:0050746 regulation of lipoprotein metabolic process(GO:0050746) regulation of protein lipidation(GO:1903059)
0.0 0.2 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.1 GO:1900115 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of BMP from receptor via BMP binding(GO:0038098) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.6 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.6 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.5 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.9 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.6 GO:0006400 tRNA modification(GO:0006400)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.1 GO:0001845 phagolysosome assembly(GO:0001845)
0.0 0.7 GO:0007338 single fertilization(GO:0007338)
0.0 0.3 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.1 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.5 GO:0030217 T cell differentiation(GO:0030217)
0.0 0.2 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.8 GO:0010038 response to metal ion(GO:0010038)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0051923 sulfation(GO:0051923)
0.0 0.4 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.5 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.1 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.0 GO:0030328 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.0 0.1 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.6 GO:0031017 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.2 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.3 GO:0030641 regulation of cellular pH(GO:0030641)
0.0 0.1 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.6 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 1.2 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.0 0.3 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.2 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.4 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.3 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.6 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.0 0.1 GO:0001678 cellular glucose homeostasis(GO:0001678)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.5 1.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 0.9 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 2.5 GO:0031430 M band(GO:0031430)
0.2 1.0 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.2 1.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 1.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 0.5 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.2 1.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 2.2 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.4 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 5.8 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 0.4 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.1 1.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.4 GO:0061702 inflammasome complex(GO:0061702)
0.1 0.5 GO:1990246 uniplex complex(GO:1990246)
0.1 1.1 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 0.5 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.1 6.4 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1 2.7 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 0.6 GO:0005921 gap junction(GO:0005921)
0.1 0.3 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 1.0 GO:0043195 terminal bouton(GO:0043195)
0.1 1.3 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.1 0.9 GO:0000145 exocyst(GO:0000145)
0.1 1.3 GO:0043186 P granule(GO:0043186)
0.1 0.5 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.3 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.0 1.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.3 GO:0005833 hemoglobin complex(GO:0005833) haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.4 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.6 GO:0070822 Sin3-type complex(GO:0070822)
0.0 1.6 GO:0042641 actomyosin(GO:0042641)
0.0 0.4 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 1.1 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 0.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.8 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.9 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.4 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.5 GO:0005776 autophagosome(GO:0005776)
0.0 1.1 GO:0030424 axon(GO:0030424)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.5 1.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.4 5.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.4 1.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.3 2.0 GO:0098809 nitrite reductase activity(GO:0098809)
0.3 2.4 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.3 1.3 GO:0004998 transferrin receptor activity(GO:0004998)
0.2 1.2 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.2 0.6 GO:0005243 gap junction channel activity(GO:0005243)
0.2 1.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 2.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 1.1 GO:0070095 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.2 0.8 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.2 0.8 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.2 0.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 0.9 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 0.6 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725) molybdenum ion binding(GO:0030151)
0.1 1.3 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.9 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.4 GO:0032090 Pyrin domain binding(GO:0032090)
0.1 0.4 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.6 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 1.3 GO:0009055 electron carrier activity(GO:0009055)
0.1 1.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.5 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.5 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 1.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.8 GO:0043495 protein anchor(GO:0043495)
0.1 0.7 GO:0015250 water channel activity(GO:0015250)
0.1 0.6 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.1 0.6 GO:0043531 ADP binding(GO:0043531)
0.1 0.6 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.4 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.3 GO:0047522 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 0.9 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.0 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.5 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 1.3 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.4 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 1.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.1 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 0.3 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.1 0.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 1.3 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 0.2 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.1 1.0 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 0.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.9 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.1 0.9 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 1.6 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.8 GO:0005507 copper ion binding(GO:0005507)
0.0 0.3 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 1.6 GO:0019955 cytokine binding(GO:0019955)
0.0 0.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 1.3 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.3 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 1.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 1.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.7 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729) CCR5 chemokine receptor binding(GO:0031730)
0.0 0.4 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 5.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 2.4 GO:0000149 SNARE binding(GO:0000149)
0.0 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 1.3 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.1 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.9 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.2 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0 0.2 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.0 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.0 2.4 GO:0019900 kinase binding(GO:0019900)
0.0 0.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0005009 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.9 GO:0031490 chromatin DNA binding(GO:0031490)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 0.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 0.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 3.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 2.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 8.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 0.7 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.7 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.9 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.1 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint