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DANIO-CODE

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Results for ets2

Z-value: 0.82

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Transcription factors associated with ets2

Gene Symbol Gene ID Gene Info
ENSDARG00000103980 v-ets avian erythroblastosis virus E26 oncogene homolog 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ets2dr10_dc_chr10_+_187740_187782-0.342.0e-01Click!

Activity profile of ets2 motif

Sorted Z-values of ets2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ets2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr23_-_9924987 2.39 ENSDART00000005015
protein kinase C binding protein 1, like
chr5_+_4033390 1.75 ENSDART00000149185
spermidine/spermine N1-acetyltransferase 1a, duplicate 2
chr13_+_11913290 1.71 ENSDART00000079398
guanine nucleotide binding protein (G protein), gamma 2
chr4_-_22590638 1.69 ENSDART00000137814
hematopoietic cell-specific Lyn substrate 1
chr7_+_67244332 1.59 ENSDART00000170322
ribosomal protein L13
chr20_+_54289892 1.57 ENSDART00000060444
ribosomal protein S29
chr5_+_52393600 1.54

chr18_+_23004984 1.52 ENSDART00000171871
core-binding factor, beta subunit
chr21_+_28465617 1.48 ENSDART00000140229
OTU deubiquitinase, ubiquitin aldehyde binding 1a
chr25_-_13456748 1.46 ENSDART00000139290
anoctamin 10b
chr23_+_34030832 1.43 ENSDART00000172069
small nuclear ribonucleoprotein polypeptide G
chr13_+_11912981 1.42 ENSDART00000158244
guanine nucleotide binding protein (G protein), gamma 2
chr1_+_38099962 1.41 ENSDART00000166864
signal peptidase complex subunit 3
chr23_+_27749014 1.39 ENSDART00000128833
ribosomal protein S26
chr19_+_12058673 1.37 ENSDART00000111568
polymerase (RNA) II (DNA directed) polypeptide K
chr20_+_16843502 1.34 ENSDART00000050308
calmodulin 1b
chr23_+_36822250 1.33

chr19_+_33267939 1.32 ENSDART00000176726
ribosomal protein L30
chr11_-_44724371 1.29 ENSDART00000166501
calcium activated nucleotidase 1b
chr11_+_8119829 1.28 ENSDART00000011183
protein kinase, cAMP-dependent, catalytic, beta a
chr5_-_41672394 1.27 ENSDART00000164363
si:ch211-207c6.2
chr21_+_25034997 1.25 ENSDART00000167523
DIX domain containing 1b
chr10_+_22759607 1.24

chr16_+_5470544 1.22

chr13_-_24181106 1.22 ENSDART00000004420
RAB4a, member RAS oncogene family
chr7_-_25422583 1.21 ENSDART00000135415
dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
chr6_-_49064365 1.21 ENSDART00000156124
si:ch211-105j21.9
chr4_+_7668939 1.20 ENSDART00000149218
ELK3, ETS-domain protein
chr7_+_19122698 1.20 ENSDART00000162700
small nuclear ribonucleoprotein polypeptide F
chr10_+_26705729 1.20 ENSDART00000147013
si:ch73-52f15.5
chr16_+_25401922 1.20 ENSDART00000172514
ENSDART00000086409
dynein, cytoplasmic 1, intermediate chain 1
chr11_-_42826276 1.19

chr9_-_56644466 1.19 ENSDART00000149851
ribosomal protein L31
chr8_+_15201828 1.17 ENSDART00000132216
polyamine oxidase (exo-N4-amino) 1
chr9_-_42682501 1.17 ENSDART00000048320
tissue factor pathway inhibitor a
chr14_-_38538068 1.16 ENSDART00000173300
ubiquinol-cytochrome c reductase, complex III subunit VII
chr5_-_66792947 1.14 ENSDART00000147009
si:dkey-251i10.2
chr16_-_23882488 1.14 ENSDART00000077834
ribosomal protein S27, isoform 2
chr8_+_54171992 1.13 ENSDART00000122692
ENSDARG00000086057
chr22_-_14090538 1.13 ENSDART00000105717
aldehyde oxidase 5
chr10_+_7712522 1.10 ENSDART00000157608
family with sequence similarity 136, member A
chr25_+_7660590 1.08 ENSDART00000155016
diacylglycerol kinase, zeta b
chr3_+_31542311 1.08

chr20_-_36897042 1.08 ENSDART00000015190
peptidyl-tRNA hydrolase domain containing 1
chr16_-_24696036 1.08

chr9_-_7695437 1.07 ENSDART00000102715
tubulin, alpha 8 like 3
chr12_+_42281025 1.06 ENSDART00000167324
early B-cell factor 3a
chr24_+_5906087 1.06 ENSDART00000131768
abl-interactor 1a
chr18_-_3056732 1.04 ENSDART00000162657
ribosomal protein S3
chr10_+_16589111 1.04 ENSDART00000084278
isochorismatase domain containing 1
KN149998v1_+_54953 1.02

chr7_+_22552724 1.02 ENSDART00000101459
ENSDART00000159743
phosphorylase, glycogen, muscle b
chr20_+_14979154 1.00 ENSDART00000118157
dre-mir-199-1
chr1_+_1953714 0.99 ENSDART00000164488
ENSDART00000167050
ENSDART00000122626
ENSDART00000128187
muscleblind-like splicing regulator 2
chr22_-_23641813 0.99 ENSDART00000159622
complement factor H
chr22_+_5657904 0.95 ENSDART00000138102
deoxyribonuclease 1 like 4, tandem duplicate 2
chr10_+_9764591 0.95 ENSDART00000091780
ring finger and CCCH-type domains 2
chr6_+_23611854 0.92 ENSDART00000167795
phosphoinositide-3-kinase, regulatory subunit 6a
chr3_+_27684309 0.92

chr6_-_12224562 0.92 ENSDART00000090266
ENSDART00000144028
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr18_+_24932972 0.91 ENSDART00000008638
repulsive guidance molecule family member a
chr3_-_47328771 0.89 ENSDART00000020168
potassium channel tetramerization domain containing 5a
chr2_+_35871754 0.88 ENSDART00000134918
DEAH (Asp-Glu-Ala-His) box helicase 9
chr15_-_2689005 0.88 ENSDART00000063325
claudin f
chr21_+_25729090 0.88 ENSDART00000021664
claudin b
chr4_+_11312432 0.88 ENSDART00000051792
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa
chr6_-_49217110 0.86 ENSDART00000143252
ENSDART00000103376
ENSDART00000132347
ENSDART00000132131
nerve growth factor b (beta polypeptide)
chr5_-_62747812 0.86

chr16_-_39620777 0.85 ENSDART00000039832
transforming growth factor beta receptor 2b
chr3_+_19471228 0.85 ENSDART00000025358
integrin beta 3a
chr6_-_40660116 0.84 ENSDART00000154359
peptidylprolyl isomerase (cyclophilin)-like 1
chr3_-_27516974 0.84 ENSDART00000151675
si:ch211-157c3.4
chr25_-_20283460 0.84 ENSDART00000067454
potassium channel tetramerization domain containing 15a
chr3_+_21928483 0.84 ENSDART00000155739
KAT8 regulatory NSL complex subunit 1b
chr1_+_157674 0.84 ENSDART00000152205
ENSDART00000160843
cullin 4A
chr15_-_47264693 0.83

chr3_-_34208423 0.82 ENSDART00000151634
trinucleotide repeat containing 6C1
chr11_+_3969982 0.82 ENSDART00000082379
signal peptidase complex subunit 1
chr21_+_30757831 0.82 ENSDART00000139486
ENSDARG00000030006
chr11_-_42826308 0.81

chr21_-_40694583 0.81 ENSDART00000045124
proteasome maturation protein
chr8_+_17148864 0.80 ENSDART00000140531
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)
chr17_+_11264847 0.79 ENSDART00000153602
ENSDARG00000097666
chr3_+_54327353 0.79 ENSDART00000127487
eukaryotic translation initiation factor 3, subunit G
chr23_+_17939650 0.79 ENSDART00000162822
nascent polypeptide-associated complex alpha subunit
KN150680v1_+_10854 0.79

chr3_+_13043951 0.79

chr13_+_46040822 0.78 ENSDART00000056987
MARCKS-like 1a
chr18_-_39491932 0.77 ENSDART00000122930
secretogranin III
chr8_-_22486746 0.77 ENSDART00000101616
si:ch211-261n11.5
chr5_+_4906729 0.76 ENSDART00000139553
mitogen-activated protein kinase associated protein 1
chr13_+_28689749 0.76 ENSDART00000101653
ENSDARG00000062790
chr11_-_176933 0.76 ENSDART00000172920
cyclin-dependent kinase 4
chr19_-_15288270 0.76 ENSDART00000151451
phosphatase and actin regulator 4a
chr19_-_1905372 0.76 ENSDART00000029646
ribosomal protein, large, P1
chr4_-_25496215 0.76 ENSDART00000041402
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr15_-_4537178 0.75 ENSDART00000155619
ENSDART00000128602
transcription factor Dp-2
chr17_+_443558 0.75 ENSDART00000171386
zgc:194887
chr16_+_38327295 0.74 ENSDART00000085143
BCL2/adenovirus E1B 19kD interacting protein, like
KN150503v1_-_598 0.74 ENSDART00000174608
ENSDARG00000108333
chr1_-_44239584 0.73 ENSDART00000137216
transmembrane protein 176
chr7_-_66653301 0.73 ENSDART00000155954
adrenomedullin a
chr6_-_41087828 0.73 ENSDART00000028217
serine/arginine-rich splicing factor 3a
KN149874v1_+_3991 0.73

chr22_-_21151096 0.73 ENSDART00000131743
si:ch211-87h14.3
chr17_-_29102320 0.73 ENSDART00000104204
forkhead box G1a
chr18_+_7625616 0.72 ENSDART00000131662
ENSDARG00000092191
chr14_+_38538151 0.72 ENSDART00000043317
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr11_-_16840339 0.72 ENSDART00000122222
succinate-CoA ligase, GDP-forming, beta subunit
chr3_+_12432686 0.71

chr14_-_14337584 0.71 ENSDART00000167119
ENSDART00000168027
ENSDART00000167521
zinc finger protein 185 with LIM domain
chr8_-_17148743 0.71 ENSDART00000025803
polymerase (DNA directed), alpha 2
chr21_+_16987306 0.71 ENSDART00000080628
actin related protein 2/3 complex, subunit 3
chr5_-_63031745 0.71

chr2_-_37832757 0.70

KN149874v1_+_3898 0.70

chr24_-_21325777 0.70 ENSDART00000109848
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr25_-_26292712 0.70 ENSDART00000067114
F-box and leucine-rich repeat protein 22
chr4_-_978592 0.69 ENSDART00000160902
N-acetylgalactosaminidase, alpha
chr18_-_25002972 0.69 ENSDART00000163449
chromodomain helicase DNA binding protein 2
chr9_-_21427331 0.69 ENSDART00000102143
COX17 cytochrome c oxidase copper chaperone
chr16_+_46530388 0.69 ENSDART00000058324
rapunzel 4
chr8_+_41639900 0.69 ENSDART00000136492
si:ch211-158d24.4
chr20_+_7596461 0.68 ENSDART00000127975
ENSDART00000132481
ENSDART00000144551
biogenesis of lysosomal organelles complex-1, subunit 2
chr24_+_9272045 0.68 ENSDART00000132724
si:ch211-285f17.1
chr14_+_4169846 0.68 ENSDART00000038301
glucosamine-6-phosphate deaminase 2
chr18_+_36650892 0.68 ENSDART00000098980
zinc finger protein 296
chr3_+_23540206 0.68

chr20_+_26993709 0.67 ENSDART00000133293
finTRIM family, member 97
chr4_+_22757046 0.67

chr12_-_308929 0.67 ENSDART00000066579
ENSDART00000171396
6-pyruvoyltetrahydropterin synthase
chr12_-_28840796 0.67

chr7_+_69232260 0.67 ENSDART00000073861
GABA(A) receptor-associated protein b
chr10_-_27261937 0.67

chr8_-_40231417 0.66 ENSDART00000162020
lysine (K)-specific demethylase 2Ba
chr6_+_39362786 0.65 ENSDART00000151322
ENSDARG00000028618
chr13_+_27654900 0.65 ENSDART00000160550
ENSDARG00000102040
chr4_-_25847471 0.65 ENSDART00000142491
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr7_-_24350507 0.65 ENSDART00000127155
phosphatidylinositol 3-kinase, catalytic subunit type 3
chr16_+_20932876 0.65 ENSDART00000079343
JAZF zinc finger 1b
chr19_-_5142310 0.65 ENSDART00000130062
chromodomain helicase DNA binding protein 4a
chr17_+_11346554 0.65 ENSDART00000113669
EF-hand calcium binding domain 2
chr22_+_980836 0.64 ENSDART00000149743
peroxisome proliferator-activated receptor delta a
chr2_+_22839514 0.64 ENSDART00000167915
leucine rich repeat containing 8 family, member Da
chr16_+_55090464 0.64 ENSDART00000161086
C-x(9)-C motif containing 1
chr10_-_7712439 0.63 ENSDART00000159330
prenylcysteine oxidase 1
chr4_-_9666436 0.63 ENSDART00000133214
cyclin D binding myb-like transcription factor 1
chr2_+_37833161 0.63 ENSDART00000166352
short chain dehydrogenase/reductase family 39U, member 1
chr5_+_3965645 0.62 ENSDART00000100061
peroxiredoxin 4
chr17_+_45412784 0.62 ENSDART00000122128
neudesin neurotrophic factor
chr10_+_7043530 0.62

chr15_-_47264619 0.62

chr2_+_47885551 0.61

chr12_+_16403743 0.61 ENSDART00000058665
kinesin family member 20Bb
chr24_-_9819862 0.61 ENSDART00000092975
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr16_+_42067930 0.61 ENSDART00000102789
Fli-1 proto-oncogene, ETS transcription factor b
chr8_-_23102555 0.61

chr7_+_890752 0.61 ENSDART00000111531
ependymin-like 1
chr2_+_54060488 0.61 ENSDART00000167239
ENSDARG00000099376
chr2_-_32372801 0.61 ENSDART00000143348
ENSDARG00000093778
chr10_+_36254196 0.61 ENSDART00000114102
cytochrome c oxidase assembly factor 4 homolog
chr1_+_44141337 0.60

chr5_+_30143469 0.59 ENSDART00000138292
finTRIM family, member 83
chr19_-_35512932 0.59

chr21_-_11539798 0.59 ENSDART00000144770
calpastatin
chr17_-_7990960 0.58

chr2_-_10020770 0.58 ENSDART00000046587
adaptor-related protein complex 2, mu 1 subunit, a
chr25_+_5695630 0.58 ENSDART00000161035
chromosome 12 open reading frame 75
chr19_+_26065401 0.58 ENSDART00000146947
tachykinin 1
chr12_+_1572834 0.58

chr19_+_9231110 0.57 ENSDART00000127803
CDC-like kinase 2a
chr2_-_42643045 0.57 ENSDART00000139929
extended synaptotagmin-like protein 2a
chr2_+_9263844 0.57 ENSDART00000028906
phosphatidylinositol glycan anchor biosynthesis, class K
chr2_-_11879076 0.56 ENSDART00000145108
ENSDARG00000039203
chr25_+_34069931 0.56

chr9_-_42682631 0.56 ENSDART00000047653
tissue factor pathway inhibitor a
chr9_-_19951894 0.56 ENSDART00000146841
si:ch211-141e20.2
chr10_-_16109057 0.56 ENSDART00000141868
si:dkey-184a18.5
chr3_-_12432661 0.56

chr7_-_23933499 0.56 ENSDART00000087298
guanosine monophosphate reductase 2
chr23_-_28286971 0.56

chr14_+_49921861 0.56 ENSDART00000173240
zgc:154054
chr14_+_23412305 0.56 ENSDART00000136909
glucosamine-6-phosphate deaminase 1
KN149909v1_-_34614 0.55

chr8_-_24276524 0.55

chr17_+_53146423 0.55 ENSDART00000163456
ENSDART00000158973
ENSDARG00000102122
chr8_-_4529979 0.55 ENSDART00000143511
ENSDART00000134324
glycoprotein Ib (platelet), beta polypeptide
chr3_+_52974018 0.55 ENSDART00000156490
PET100 homolog
chr24_-_10928910 0.55 ENSDART00000127398
ENSDARG00000090548
chr7_+_36267647 0.55 ENSDART00000173653
chromodomain helicase DNA binding protein 9
chr16_+_21891184 0.54

chr13_-_37527812 0.54 ENSDART00000143806
si:dkey-188i13.11
chr23_+_1675422 0.54

chr22_-_31722970 0.54 ENSDART00000128247
LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
chr3_+_59491893 0.54 ENSDART00000084729
platelet/endothelial cell adhesion molecule 1
chr11_-_36088889 0.53 ENSDART00000146495
proteasome subunit alpha 5
chr8_+_19457907 0.53 ENSDART00000011258
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
chr11_+_15935769 0.53 ENSDART00000158824
chitobiase, di-N-acetyl-
chr22_+_22235270 0.53 ENSDART00000017755
UBX domain protein 6
chr7_+_20046425 0.53 ENSDART00000131019
acyl-CoA dehydrogenase, very long chain

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0002280 monocyte activation involved in immune response(GO:0002280) negative regulation of phagocytosis(GO:0050765)
0.4 1.7 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.4 1.5 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.3 0.9 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.2 0.5 GO:0050764 regulation of phagocytosis(GO:0050764)
0.2 0.9 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 1.5 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.2 0.6 GO:0030328 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.2 0.6 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.2 0.5 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.2 0.9 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.2 0.7 GO:0071280 cellular response to copper ion(GO:0071280)
0.2 1.5 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 0.5 GO:0071800 podosome assembly(GO:0071800)
0.1 0.4 GO:0051101 regulation of DNA binding(GO:0051101) regulation of oligodendrocyte progenitor proliferation(GO:0070445) negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.1 1.7 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.4 GO:0050864 regulation of B cell activation(GO:0050864)
0.1 0.4 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) actin filament debranching(GO:0071846)
0.1 0.5 GO:0048790 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.1 0.7 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 0.4 GO:0061549 sympathetic ganglion development(GO:0061549)
0.1 1.1 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.4 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.8 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 0.3 GO:0001955 blood vessel maturation(GO:0001955)
0.1 1.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.3 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 0.8 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.3 GO:0014005 microglia development(GO:0014005)
0.1 0.5 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.5 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.4 GO:0050820 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.1 0.7 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.1 3.1 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.1 0.6 GO:0030242 pexophagy(GO:0030242)
0.1 2.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 0.7 GO:0086003 cardiac muscle cell contraction(GO:0086003)
0.1 0.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.7 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.1 0.8 GO:0070527 platelet aggregation(GO:0070527)
0.1 1.1 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.9 GO:0097320 membrane tubulation(GO:0097320)
0.1 0.2 GO:0072501 cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320) cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.2 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.1 0.9 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 0.9 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 1.2 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.4 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.2 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded DNA demethylation(GO:0035552)
0.1 0.9 GO:0043584 nose development(GO:0043584)
0.1 1.3 GO:0010737 protein kinase A signaling(GO:0010737)
0.1 0.5 GO:0010887 negative regulation of cholesterol storage(GO:0010887) negative regulation of lipid storage(GO:0010888)
0.1 0.2 GO:0098751 bone cell development(GO:0098751)
0.1 0.3 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 1.0 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.1 1.8 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 0.3 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 0.4 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.6 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 1.0 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.1 0.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 1.7 GO:0007596 blood coagulation(GO:0007596) hemostasis(GO:0007599)
0.1 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.2 GO:0060997 dendritic spine development(GO:0060996) dendritic spine morphogenesis(GO:0060997)
0.1 1.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.7 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 1.2 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.3 GO:0009791 post-embryonic development(GO:0009791)
0.0 0.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.4 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846) positive regulation of TORC1 signaling(GO:1904263)
0.0 0.4 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.7 GO:0050773 regulation of dendrite development(GO:0050773)
0.0 0.2 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.5 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.3 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.4 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.7 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.2 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.7 GO:0051014 actin filament severing(GO:0051014)
0.0 0.8 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.5 GO:0021794 thalamus development(GO:0021794)
0.0 0.5 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.4 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.9 GO:0031167 rRNA methylation(GO:0031167)
0.0 1.6 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 1.8 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.2 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 2.3 GO:0010970 establishment of localization by movement along microtubule(GO:0010970)
0.0 0.2 GO:1901908 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169) diadenosine polyphosphate metabolic process(GO:0015959) diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 1.0 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.3 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.7 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.7 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.8 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.1 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 1.4 GO:0006612 protein targeting to membrane(GO:0006612)
0.0 0.4 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.6 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.2 GO:0003139 secondary heart field specification(GO:0003139)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.7 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 1.3 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.4 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 0.9 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.2 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.2 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.6 GO:0009615 response to virus(GO:0009615)
0.0 0.1 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.4 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 1.8 GO:0008154 actin polymerization or depolymerization(GO:0008154)
0.0 0.2 GO:0097581 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.6 GO:0006821 chloride transport(GO:0006821)
0.0 0.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.3 2.2 GO:0005787 signal peptidase complex(GO:0005787)
0.3 3.1 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.3 0.8 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.2 0.7 GO:1902560 GMP reductase complex(GO:1902560)
0.2 0.7 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.2 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.2 0.6 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.2 0.5 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.2 0.9 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 1.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.4 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 1.9 GO:0030315 T-tubule(GO:0030315)
0.1 0.9 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.1 5.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.6 GO:0030897 HOPS complex(GO:0030897)
0.1 1.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 1.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 4.9 GO:0022626 cytosolic large ribosomal subunit(GO:0022625) cytosolic ribosome(GO:0022626)
0.1 0.5 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.1 0.6 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 1.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.6 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.2 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.7 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.8 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.7 GO:0044545 NSL complex(GO:0044545)
0.0 1.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0016586 RSC complex(GO:0016586)
0.0 1.2 GO:0008305 integrin complex(GO:0008305)
0.0 0.8 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.5 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.2 GO:0030175 filopodium(GO:0030175)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0030990 intraciliary transport particle(GO:0030990)
0.0 0.3 GO:0071797 LUBAC complex(GO:0071797)
0.0 2.2 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.4 GO:0070847 core mediator complex(GO:0070847)
0.0 0.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.0 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.5 GO:0030018 Z disc(GO:0030018)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.9 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.8 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0000938 GARP complex(GO:0000938)
0.0 0.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.5 GO:0001726 ruffle(GO:0001726)
0.0 0.8 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 2.6 GO:0005874 microtubule(GO:0005874)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0019809 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.4 1.2 GO:0046592 polyamine oxidase activity(GO:0046592)
0.4 1.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.3 1.2 GO:0045503 dynein light chain binding(GO:0045503)
0.3 0.9 GO:0034713 transforming growth factor beta receptor activity, type II(GO:0005026) type I transforming growth factor beta receptor binding(GO:0034713)
0.3 1.1 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.3 3.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 0.7 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.2 0.7 GO:0004774 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.2 1.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 0.6 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.2 0.9 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.2 0.6 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.2 1.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.2 1.3 GO:0004691 AMP-activated protein kinase activity(GO:0004679) cAMP-dependent protein kinase activity(GO:0004691)
0.2 0.9 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 0.7 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2 0.5 GO:0004568 chitinase activity(GO:0004568)
0.2 0.9 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.2 1.0 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.2 1.0 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.2 0.6 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.2 1.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.4 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.9 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.4 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.1 0.5 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.7 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.1 1.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.7 GO:0015925 galactosidase activity(GO:0015925)
0.1 0.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.9 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.3 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 1.3 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.5 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.5 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.7 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.4 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.2 GO:0035515 DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
0.1 0.3 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.1 0.6 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.8 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.9 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 10.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 0.5 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.2 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.3 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.3 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.6 GO:0035004 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004)
0.0 0.4 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 1.2 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.8 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 1.2 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 1.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.5 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.2 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 1.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0003874 6-pyruvoyltetrahydropterin synthase activity(GO:0003874)
0.0 0.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.8 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.3 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.8 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.3 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.2 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 3.5 GO:0051015 actin filament binding(GO:0051015)
0.0 0.6 GO:0045296 cadherin binding(GO:0045296)
0.0 2.2 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.4 GO:0005178 integrin binding(GO:0005178)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.6 GO:0005254 chloride channel activity(GO:0005254)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.9 GO:0051082 unfolded protein binding(GO:0051082)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 0.5 PID ALK2 PATHWAY ALK2 signaling events
0.1 2.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 1.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.4 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.4 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.3 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.3 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.8 PID E2F PATHWAY E2F transcription factor network
0.0 0.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.3 2.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 1.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 2.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 0.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 5.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 4.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 0.5 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 0.3 REACTOME GABA B RECEPTOR ACTIVATION Genes involved in GABA B receptor activation
0.1 1.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 0.7 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 0.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 0.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 0.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.6 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.6 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation