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Results for evx2

Z-value: 0.59

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Transcription factors associated with evx2

Gene Symbol Gene ID Gene Info
ENSDARG00000059255 even-skipped homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
evx2dr10_dc_chr9_+_2001849_2001884-0.581.9e-02Click!

Activity profile of evx2 motif

Sorted Z-values of evx2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of evx2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr23_+_43868027 1.87 ENSDART00000112598
ENSDART00000169576
OTU deubiquitinase 4
chr25_-_9889107 1.76 ENSDART00000137407
ENSDARG00000093575
chr5_+_19429500 1.30 ENSDART00000168868
ankyrin repeat domain 13A
chr5_+_19429620 1.29 ENSDART00000088819
ankyrin repeat domain 13A
chr15_-_20189097 0.87 ENSDART00000152355
mediator complex subunit 13b
chr7_+_22042296 0.80 ENSDART00000123457
transmembrane protein 102
chr14_+_21522672 0.72 ENSDART00000122739
C-terminal binding protein 1
chr16_-_25620142 0.69 ENSDART00000077420
dystrobrevin binding protein 1a
chr13_-_36537892 0.69 ENSDART00000085319
son of sevenless homolog 2 (Drosophila)
chr5_+_21563654 0.69 ENSDART00000045574
shisa family member 2a
chr25_-_9889072 0.67 ENSDART00000137407
ENSDARG00000093575
chr21_-_13565401 0.66 ENSDART00000151547
patatin-like phospholipase domain containing 7a
chr13_-_36538099 0.62

chr16_-_25620064 0.57 ENSDART00000077420
dystrobrevin binding protein 1a
chr5_+_21564036 0.51 ENSDART00000045574
shisa family member 2a
chr5_+_4906690 0.50 ENSDART00000124022
mitogen-activated protein kinase associated protein 1
chr15_-_20189405 0.47 ENSDART00000152355
mediator complex subunit 13b
chr5_+_21563703 0.34 ENSDART00000045574
shisa family member 2a
chr5_-_19429016 0.28 ENSDART00000170344
G protein-coupled receptor kinase interacting ArfGAP 2a
chr11_-_27378184 0.27 ENSDART00000157337
ENSDARG00000097455
chr2_-_2252088 0.23 ENSDART00000164674
synovial sarcoma translocation, chromosome 18 (H. sapiens)
chr19_-_19806070 0.22 ENSDART00000165206
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1b
chr24_-_24859135 0.20 ENSDART00000136860
zinc finger, DHHC-type containing 20b
chr7_-_68229115 0.19

chr7_-_26260802 0.15 ENSDART00000121698
SUMO1/sentrin/SMT3 specific peptidase 3b
chr5_-_25133456 0.05 ENSDART00000051566
zgc:101016

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.2 1.3 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 1.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.7 GO:0051287 NAD binding(GO:0051287)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.7 PID ATM PATHWAY ATM pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac