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Results for fli1b

Z-value: 0.95

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Transcription factors associated with fli1b

Gene Symbol Gene ID Gene Info
ENSDARG00000040080 Fli-1 proto-oncogene, ETS transcription factor b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
fli1bdr10_dc_chr16_+_42067930_420680140.911.3e-06Click!

Activity profile of fli1b motif

Sorted Z-values of fli1b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of fli1b

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr23_-_9924987 3.45 ENSDART00000005015
protein kinase C binding protein 1, like
chr5_-_62747812 3.42

chr7_-_25422583 2.61 ENSDART00000135415
dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
chr3_+_31542311 2.39

chr8_-_7049946 2.38 ENSDART00000045669
ENSDART00000162950
keratin 73
chr7_+_19765237 2.27 ENSDART00000100808
B-cell CLL/lymphoma 6, member B
chr5_-_1325831 2.22

chr18_+_38307946 2.17 ENSDART00000134247
LIM domain only 2 (rhombotin-like 1)
chr11_+_8119829 2.14 ENSDART00000011183
protein kinase, cAMP-dependent, catalytic, beta a
chr5_-_62747914 2.10

chr15_-_4537178 1.89 ENSDART00000155619
ENSDART00000128602
transcription factor Dp-2
chr23_+_13911019 1.78 ENSDART00000168545
zinc finger and BTB domain containing 46
chr9_-_34129128 1.75

chr5_-_67043355 1.75 ENSDART00000134386
Rho GTPase activating protein 31
chr5_-_34016383 1.71 ENSDART00000050271
ENSDART00000097975
hexosaminidase B (beta polypeptide)
chr18_-_25002972 1.70 ENSDART00000163449
chromodomain helicase DNA binding protein 2
chr14_+_49921861 1.67 ENSDART00000173240
zgc:154054
chr19_-_2399429 1.64 ENSDART00000043595
twist family bHLH transcription factor 1a
chr22_+_5657904 1.64 ENSDART00000138102
deoxyribonuclease 1 like 4, tandem duplicate 2
chr23_+_36822250 1.59

chr19_-_325337 1.58 ENSDART00000147635
glycerol-3-phosphate dehydrogenase 1c
chr16_-_39620777 1.57 ENSDART00000039832
transforming growth factor beta receptor 2b
chr14_+_13147115 1.56 ENSDART00000054849
plastin 3 (T isoform)
chr5_+_36487425 1.56 ENSDART00000049900
transgelin 2
chr4_-_17735989 1.47 ENSDART00000016658
choline phosphotransferase 1
chr5_-_41672394 1.47 ENSDART00000164363
si:ch211-207c6.2
chr5_-_15774816 1.46 ENSDART00000090684
kringle containing transmembrane protein 1
chr4_-_22590638 1.45 ENSDART00000137814
hematopoietic cell-specific Lyn substrate 1
chr5_+_4033390 1.40 ENSDART00000149185
spermidine/spermine N1-acetyltransferase 1a, duplicate 2
chr21_-_11539798 1.39 ENSDART00000144770
calpastatin
chr20_+_20600211 1.37 ENSDART00000036124
SIX homeobox 1b
chr9_+_54692834 1.36

chr7_+_34482282 1.36

chr22_-_13139894 1.35 ENSDART00000105762
aryl hydrocarbon receptor 2
chr19_-_35512932 1.35

chr4_+_3344998 1.34 ENSDART00000075320
nicotinamide phosphoribosyltransferase a
chr22_-_23641813 1.31 ENSDART00000159622
complement factor H
chr1_+_49041978 1.31 ENSDART00000140824
si:ch211-149l1.2
chr17_-_29102320 1.30 ENSDART00000104204
forkhead box G1a
chr15_-_2689005 1.30 ENSDART00000063325
claudin f
chr13_-_24181106 1.30 ENSDART00000004420
RAB4a, member RAS oncogene family
chr16_+_1338291 1.28 ENSDART00000149299
ceramide synthase 2b
chr7_+_22552724 1.27 ENSDART00000101459
ENSDART00000159743
phosphorylase, glycogen, muscle b
chr7_+_67244332 1.26 ENSDART00000170322
ribosomal protein L13
chr23_+_17939650 1.25 ENSDART00000162822
nascent polypeptide-associated complex alpha subunit
chr24_+_36746202 1.25 ENSDART00000159017
si:ch73-334d15.4
chr8_-_40231417 1.24 ENSDART00000162020
lysine (K)-specific demethylase 2Ba
chr24_+_5906087 1.24 ENSDART00000131768
abl-interactor 1a
chr18_+_23004984 1.23 ENSDART00000171871
core-binding factor, beta subunit
chr2_+_22839514 1.23 ENSDART00000167915
leucine rich repeat containing 8 family, member Da
chr19_-_35739239 1.21

chr11_-_25803101 1.21 ENSDART00000088888
kazrin, periplakin interacting protein b
chr3_+_13043951 1.21

chr19_-_35513216 1.21

chr16_+_42067930 1.20 ENSDART00000102789
Fli-1 proto-oncogene, ETS transcription factor b
chr22_-_120677 1.18

chr13_+_11913290 1.18 ENSDART00000079398
guanine nucleotide binding protein (G protein), gamma 2
chr24_-_10928910 1.17 ENSDART00000127398
ENSDARG00000090548
chr10_+_9764591 1.16 ENSDART00000091780
ring finger and CCCH-type domains 2
chr25_+_7660590 1.15 ENSDART00000155016
diacylglycerol kinase, zeta b
chr20_-_36897042 1.15 ENSDART00000015190
peptidyl-tRNA hydrolase domain containing 1
chr12_+_27370834 1.14 ENSDART00000105661
mesenchyme homeobox 1
chr17_+_1610578 1.14 ENSDART00000082101
protein phosphatase 2, regulatory subunit B', gamma a
chr2_-_3317258 1.14 ENSDART00000167944
wingless-type MMTV integration site family, member 3A
chr21_+_30434147 1.13 ENSDART00000147375
sorting nexin 12
chr7_-_64637419 1.11 ENSDART00000020456
matrix metallopeptidase 15b
chr6_+_30681170 1.09 ENSDART00000112294
tetratricopeptide repeat domain 22
chr9_-_23346038 1.08 ENSDART00000135461
LY6/PLAUR domain containing 6B
chr12_-_28840796 1.07

chr13_+_23065500 1.06 ENSDART00000158370
sorbin and SH3 domain containing 1
chr23_-_15807415 1.06 ENSDART00000178557
ENSDARG00000108083
chr5_+_18740715 1.06 ENSDART00000089173
ATPase, class I, type 8B, member 5a
chr9_-_31714290 1.06 ENSDART00000127214
transmembrane and tetratricopeptide repeat containing 4
chr18_+_91971 1.05

chr13_+_16130212 1.05 ENSDART00000125813
molybdenum cofactor sulfurase
chr14_-_31128891 1.05

chr13_-_39365252 1.05 ENSDART00000019379
MARVEL domain containing 1
chr16_+_38327295 1.05 ENSDART00000085143
BCL2/adenovirus E1B 19kD interacting protein, like
chr16_-_36991800 1.04 ENSDART00000171351
aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase)
KN149998v1_+_54953 1.04

chr23_+_13910925 1.04 ENSDART00000168545
zinc finger and BTB domain containing 46
chr16_-_26803204 1.03 ENSDART00000162665
epithelial splicing regulatory protein 1
chr19_+_33267939 1.03 ENSDART00000176726
ribosomal protein L30
chr16_-_42063851 1.02 ENSDART00000045403
ets variant 2
chr13_+_25298383 1.01

chr21_-_35806638 1.01 ENSDART00000172245
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr3_+_24327586 1.00 ENSDART00000153551
chromobox homolog 6b
chr9_-_7695437 1.00 ENSDART00000102715
tubulin, alpha 8 like 3
chr25_+_18460166 1.00 ENSDART00000073726
caveolin 2
chr10_+_22759607 1.00

chr20_+_16843502 1.00 ENSDART00000050308
calmodulin 1b
chr17_+_3842688 0.99 ENSDART00000170822
thioredoxin-related transmembrane protein 4
chr7_+_73408688 0.99 ENSDART00000159745
Purkinje cell protein 4 like 1
chr19_+_34114412 0.99 ENSDART00000162517
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr14_-_48951428 0.99 ENSDART00000157785
Rap guanine nucleotide exchange factor (GEF) 2
chr11_+_26371444 0.99 ENSDART00000042322
microtubule-associated protein 1 light chain 3 alpha
chr9_-_1949904 0.98 ENSDART00000082355
homeobox D4a
chr24_+_9272045 0.97 ENSDART00000132724
si:ch211-285f17.1
chr24_+_42884 0.97 ENSDART00000122785
zgc:152808
chr13_+_11912981 0.97 ENSDART00000158244
guanine nucleotide binding protein (G protein), gamma 2
chr24_-_6048914 0.97 ENSDART00000146830
ENSDART00000021981
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr8_+_54171992 0.96 ENSDART00000122692
ENSDARG00000086057
chr14_+_26498814 0.96 ENSDART00000137695
kelch-like family member 4
chr25_-_20283460 0.95 ENSDART00000067454
potassium channel tetramerization domain containing 15a
chr6_+_1895734 0.95 ENSDART00000109679
quattro
chr21_+_25729090 0.94 ENSDART00000021664
claudin b
chr9_-_9693163 0.94 ENSDART00000018228
glycogen synthase kinase 3 beta
chr22_-_14090538 0.94 ENSDART00000105717
aldehyde oxidase 5
chr14_-_425659 0.93

chr7_-_35042805 0.93 ENSDART00000005053
solute carrier family 12 (potassium/chloride transporter), member 4
chr5_+_31590746 0.93

chr23_-_29138952 0.93 ENSDART00000002812
castor zinc finger 1
chr16_+_53238110 0.92 ENSDART00000102170
ENSDARG00000069929
chr7_+_13750329 0.92 ENSDART00000091470
furin (paired basic amino acid cleaving enzyme) a
chr5_-_31275147 0.91 ENSDART00000098160
transmembrane protein 119b
chr18_+_48426375 0.90

chr20_-_40217185 0.89

chr6_-_12224562 0.89 ENSDART00000090266
ENSDART00000144028
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr17_+_381715 0.89 ENSDART00000162898
si:rp71-62i8.1
chr3_+_23638277 0.89 ENSDART00000110682
homeobox B1a
chr11_+_43924640 0.88 ENSDART00000179206
guanine nucleotide binding protein (G protein), beta polypeptide 4b
chr6_+_19795100 0.87

chr3_+_22246697 0.87 ENSDART00000155597
Rho GTPase activating protein 27, like
chr5_-_58269742 0.86 ENSDART00000122413
melanoma cell adhesion molecule a
chr12_+_36716775 0.86 ENSDART00000048927
COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
chr19_-_7069920 0.86 ENSDART00000145741
zinc finger protein 384 like
chr16_-_16582360 0.86

chr23_-_24755654 0.86 ENSDART00000104035
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr14_-_32553399 0.85 ENSDART00000169380
solute carrier family 25, member 43
chr21_+_25034997 0.85 ENSDART00000167523
DIX domain containing 1b
chr17_-_39237265 0.85 ENSDART00000050534
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr5_+_30143469 0.85 ENSDART00000138292
finTRIM family, member 83
chr1_+_35933511 0.85 ENSDART00000010632
endothelin receptor type Aa
chr24_+_18804086 0.85 ENSDART00000106186
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr25_+_34069931 0.84

chr10_-_35036872 0.84 ENSDART00000170625
SMAD family member 9
chr1_-_51862897 0.83 ENSDART00000136469
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr5_-_43686611 0.82 ENSDART00000146080
si:ch73-337l15.2
chr3_-_23558171 0.82

chr20_+_20287015 0.82 ENSDART00000002507
ras homolog family member J
chr5_+_68943914 0.82 ENSDART00000159594
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr1_-_18695214 0.82

chr3_+_23540206 0.82

chr11_+_5929544 0.81 ENSDART00000104364
ribosomal protein S15
chr3_-_50386208 0.81 ENSDART00000156709
ENSDARG00000097178
chr4_+_7668939 0.81 ENSDART00000149218
ELK3, ETS-domain protein
chr17_+_11264847 0.81 ENSDART00000153602
ENSDARG00000097666
chr8_-_19250414 0.81 ENSDART00000100473
ENSDARG00000013711
chr20_-_20502615 0.80

chr9_-_12726136 0.80

chr5_-_54954988 0.79 ENSDART00000142912
heterogeneous nuclear ribonucleoprotein K, like
chr23_+_31181140 0.79 ENSDART00000103448
T-box 18
chr7_-_64637051 0.79 ENSDART00000020456
matrix metallopeptidase 15b
chr14_-_33936261 0.78 ENSDART00000021437
glutamate receptor, ionotropic, AMPA 1a
chr3_+_25933164 0.78 ENSDART00000143697
si:dkeyp-69e1.8
chr17_+_31346338 0.77 ENSDART00000062900
inositol-trisphosphate 3-kinase A
chr23_-_28286971 0.77

chr7_-_38418301 0.77 ENSDART00000167209
apelin receptor 2
chr1_-_7456961 0.75 ENSDART00000152295
family with sequence similarity 83 member G
chr1_-_46052304 0.75 ENSDART00000142880
ENSDARG00000092950
chr13_+_28689749 0.75 ENSDART00000101653
ENSDARG00000062790
chr21_+_43204049 0.74 ENSDART00000151748
AF4/FMR2 family, member 4
chr20_+_26408687 0.74

chr5_+_45677439 0.74 ENSDART00000045598
zgc:110626
chr5_-_62816208 0.74 ENSDART00000097325
complement component 5
chr20_-_475417 0.73 ENSDART00000032212
fyn-related Src family tyrosine kinase
KN149859v1_+_16751 0.73 ENSDART00000167610
ENSDARG00000103399
chr1_+_25928481 0.73 ENSDART00000158193
coronin, actin binding protein, 2A
chr11_-_3968366 0.73 ENSDART00000171093
glycosyltransferase 8 domain containing 1
chr8_+_36888422 0.73

chr3_-_61104221 0.73 ENSDART00000155414
tectonin beta-propeller repeat containing 1b
chr11_-_36088889 0.73 ENSDART00000146495
proteasome subunit alpha 5
chr19_+_5375413 0.73 ENSDART00000141237
si:dkeyp-113d7.10
chr9_+_36051713 0.72 ENSDART00000134447
regulator of calcineurin 1a
chr12_+_28739504 0.72 ENSDART00000152991
nuclear factor, erythroid 2-like 1b
chr13_+_41998500 0.72 ENSDART00000074707
CDC42 effector protein (Rho GTPase binding) 3
chr23_+_19018062 0.72 ENSDART00000104487
cytochrome c oxidase subunit IV isoform 2
chr9_-_56644466 0.71 ENSDART00000149851
ribosomal protein L31
chr10_+_16589111 0.71 ENSDART00000084278
isochorismatase domain containing 1
chr20_+_25441689 0.71 ENSDART00000063028
connective tissue growth factor a
chr4_+_22757046 0.71

chr10_+_4717800 0.71 ENSDART00000161789
paralemmin 2
chr18_-_25659136 0.70 ENSDART00000138861
si:ch211-13k12.2
chr5_-_67043168 0.70 ENSDART00000134386
Rho GTPase activating protein 31
chr13_+_32013916 0.70 ENSDART00000020270
odd-skipped related transciption factor 1
chr23_+_36007936 0.70 ENSDART00000128533
homeo box C3a
chr5_-_12213712 0.70 ENSDART00000099749
claudin 22
chr16_-_48672056 0.70

chr10_-_11053655 0.69 ENSDART00000132995
adenylate kinase 3
chr8_+_15201828 0.69 ENSDART00000132216
polyamine oxidase (exo-N4-amino) 1
chr8_+_11604334 0.69 ENSDART00000004288
intraflagellar transport 81 homolog
chr8_-_12365342 0.68 ENSDART00000113286
PHD finger protein 19
chr13_+_24271932 0.67 ENSDART00000043002
RAB1A, member RAS oncogene family b
chr10_+_4987494 0.67 ENSDART00000121959
si:ch73-234b20.5
chr14_+_24637864 0.67 ENSDART00000170871
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr11_-_176933 0.66 ENSDART00000172920
cyclin-dependent kinase 4
chr5_-_31275259 0.66 ENSDART00000098160
transmembrane protein 119b
chr7_+_19122698 0.66 ENSDART00000162700
small nuclear ribonucleoprotein polypeptide F
chr10_+_7043530 0.66

chr10_+_29351676 0.66 ENSDART00000088973
synaptotagmin-like 2a

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0050765 monocyte activation involved in immune response(GO:0002280) negative regulation of phagocytosis(GO:0050765)
0.7 2.0 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.4 1.6 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.4 1.6 GO:0022602 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698)
0.4 2.0 GO:0048901 anterior lateral line neuromast development(GO:0048901) anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.4 2.2 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.4 1.8 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.3 0.3 GO:0042116 macrophage activation involved in immune response(GO:0002281) macrophage activation(GO:0042116)
0.3 1.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.3 1.2 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.3 0.9 GO:0070254 mucus secretion(GO:0070254)
0.3 0.9 GO:0032616 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.3 1.0 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.3 1.0 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.2 0.9 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 0.8 GO:0043586 tongue development(GO:0043586) tongue morphogenesis(GO:0043587) taste bud development(GO:0061193) taste bud morphogenesis(GO:0061194) taste bud formation(GO:0061195)
0.2 0.5 GO:1900060 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.2 0.9 GO:0021561 facial nerve development(GO:0021561)
0.2 1.1 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.2 1.0 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.2 0.7 GO:0035776 pronephric proximal tubule development(GO:0035776)
0.2 0.3 GO:0050764 regulation of phagocytosis(GO:0050764)
0.2 0.6 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168) regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.2 1.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.2 1.6 GO:0051639 actin filament network formation(GO:0051639)
0.2 1.4 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 0.6 GO:0043651 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 1.9 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 0.9 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.4 GO:0014005 microglia development(GO:0014005)
0.1 1.6 GO:0043584 nose development(GO:0043584)
0.1 0.9 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 1.5 GO:0000272 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 1.7 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.1 0.5 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.1 0.4 GO:0042590 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 0.6 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.7 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 2.1 GO:0010737 protein kinase A signaling(GO:0010737)
0.1 0.4 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.1 1.2 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.2 GO:0070528 protein kinase C signaling(GO:0070528)
0.1 0.3 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.1 0.4 GO:0072425 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.1 0.3 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.8 GO:0048796 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.1 0.4 GO:0046888 negative regulation of hormone secretion(GO:0046888)
0.1 0.4 GO:0033499 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.1 0.3 GO:0042908 xenobiotic transport(GO:0042908)
0.1 1.1 GO:0031274 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.4 GO:1901492 regulation of lymphangiogenesis(GO:1901490) positive regulation of lymphangiogenesis(GO:1901492)
0.1 2.2 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 0.9 GO:0042310 vasoconstriction(GO:0042310)
0.1 1.1 GO:0021794 thalamus development(GO:0021794)
0.1 2.1 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.1 0.5 GO:0061075 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.1 0.8 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 1.1 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.3 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 2.1 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.1 0.4 GO:0072530 purine-containing compound transmembrane transport(GO:0072530)
0.1 0.5 GO:0021754 facial nucleus development(GO:0021754)
0.1 1.0 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 1.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 0.3 GO:0006788 heme oxidation(GO:0006788)
0.1 0.2 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.7 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.2 GO:0099565 chemical synaptic transmission, postsynaptic(GO:0099565)
0.1 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.2 GO:1900101 regulation of endoplasmic reticulum unfolded protein response(GO:1900101) negative regulation of endoplasmic reticulum unfolded protein response(GO:1900102) regulation of IRE1-mediated unfolded protein response(GO:1903894) negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.1 2.6 GO:0060037 pharyngeal system development(GO:0060037)
0.1 0.5 GO:0098508 endothelial to hematopoietic transition(GO:0098508)
0.1 0.4 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.1 0.4 GO:0061056 sclerotome development(GO:0061056)
0.1 0.7 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.2 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.1 0.4 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.5 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.2 GO:0099563 modification of synaptic structure(GO:0099563)
0.0 0.6 GO:0006465 signal peptide processing(GO:0006465)
0.0 1.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.6 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.8 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.8 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.7 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.3 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.1 GO:0070863 intestinal cholesterol absorption(GO:0030299) regulation of protein exit from endoplasmic reticulum(GO:0070861) positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.8 GO:0051014 actin filament severing(GO:0051014)
0.0 1.1 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.5 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.7 GO:0030199 collagen fibril organization(GO:0030199)
0.0 2.4 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 2.1 GO:0042552 myelination(GO:0042552)
0.0 0.9 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 1.8 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.5 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 1.4 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.2 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.4 GO:0060606 neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.6 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 1.4 GO:0001817 regulation of cytokine production(GO:0001817)
0.0 1.2 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 1.8 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.5 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.7 GO:0042073 intraciliary transport(GO:0042073)
0.0 1.2 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 0.4 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.3 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.4 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.0 0.3 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 1.1 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.1 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331) regulation of cell-cell adhesion mediated by cadherin(GO:2000047)
0.0 0.2 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.2 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.3 GO:0031623 receptor internalization(GO:0031623)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.2 GO:0072554 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 0.6 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 0.3 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.4 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 2.1 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.6 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 0.1 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.0 0.6 GO:0006414 translational elongation(GO:0006414)
0.0 0.3 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.0 GO:0048211 Golgi vesicle docking(GO:0048211)
0.0 0.3 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.6 GO:0016331 morphogenesis of embryonic epithelium(GO:0016331)
0.0 1.9 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 0.5 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.6 GO:0007422 peripheral nervous system development(GO:0007422)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.4 2.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 0.9 GO:0098594 mucin granule(GO:0098594)
0.3 0.8 GO:1902560 GMP reductase complex(GO:1902560)
0.2 1.2 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2 3.2 GO:0030315 T-tubule(GO:0030315)
0.2 2.1 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.2 0.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 0.5 GO:0043291 RAVE complex(GO:0043291)
0.2 0.5 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.4 GO:0070552 BRISC complex(GO:0070552)
0.1 0.8 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 1.0 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.8 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.5 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.1 0.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.4 GO:0016460 myosin II complex(GO:0016460)
0.1 0.6 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.1 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.0 GO:0060170 ciliary membrane(GO:0060170)
0.1 1.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.7 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.7 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.4 GO:0042583 chromaffin granule(GO:0042583)
0.1 3.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.3 GO:0030897 HOPS complex(GO:0030897)
0.1 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.7 GO:0030904 retromer complex(GO:0030904)
0.1 0.3 GO:0002102 podosome(GO:0002102)
0.0 3.9 GO:0030027 lamellipodium(GO:0030027)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 1.8 GO:0030427 site of polarized growth(GO:0030427)
0.0 1.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 2.2 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.6 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.2 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.4 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 1.1 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.5 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 1.6 GO:0005795 Golgi stack(GO:0005795)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.9 GO:0098791 Golgi subcompartment(GO:0098791)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 1.0 GO:0031965 nuclear membrane(GO:0031965)
0.0 4.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.5 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.8 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026) type I transforming growth factor beta receptor binding(GO:0034713)
0.5 1.5 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.4 1.6 GO:0019808 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.4 1.1 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.4 1.8 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.3 1.7 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.3 0.9 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.3 2.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679) cAMP-dependent protein kinase activity(GO:0004691)
0.3 1.7 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.3 0.8 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.3 1.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.3 1.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.3 1.3 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.2 0.7 GO:0046592 polyamine oxidase activity(GO:0046592)
0.2 0.7 GO:0030331 estrogen receptor binding(GO:0030331)
0.2 0.6 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.2 0.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 0.9 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.2 2.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 0.9 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 0.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 1.0 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.2 1.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.2 1.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 0.8 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.2 0.8 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2 1.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.2 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 1.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.6 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.8 GO:0060182 apelin receptor activity(GO:0060182)
0.1 1.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.4 GO:0032028 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.1 0.3 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 1.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.6 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 3.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.5 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.3 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.1 0.7 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.3 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.1 0.7 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 0.8 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 0.8 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 2.1 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.3 GO:0001727 lipid kinase activity(GO:0001727)
0.1 1.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.4 GO:0005522 profilin binding(GO:0005522)
0.1 0.2 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.7 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.7 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.0 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.5 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 1.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 1.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.6 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0034595 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0 0.3 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 2.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 4.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 4.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.8 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.1 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 4.6 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 1.6 GO:0003678 DNA helicase activity(GO:0003678)
0.0 1.2 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 1.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 2.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 2.0 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.5 GO:0019905 syntaxin binding(GO:0019905)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 0.8 PID ALK2 PATHWAY ALK2 signaling events
0.2 0.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 3.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 0.8 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 1.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 1.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.6 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.9 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.3 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.0 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.9 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.3 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.8 PID E2F PATHWAY E2F transcription factor network
0.0 0.3 PID ATM PATHWAY ATM pathway
0.0 0.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 1.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 2.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 0.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 0.8 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 1.0 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 0.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 0.6 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 0.7 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 1.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 0.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 0.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 3.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 2.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.7 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.5 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.0 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.6 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation