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Results for fosl1b+jdp2a

Z-value: 1.13

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Transcription factors associated with fosl1b+jdp2a

Gene Symbol Gene ID Gene Info
jdp2a
ENSDARG00000040137 Jun dimerization protein 2a
fosl1b
ENSDARG00000079373 FOS-like antigen 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
jdp2adr10_dc_chr17_-_50140768_50140778-0.421.0e-01Click!

Activity profile of fosl1b+jdp2a motif

Sorted Z-values of fosl1b+jdp2a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of fosl1b+jdp2a

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr9_-_30560440 3.88 ENSDART00000079068
asb11
ankyrin repeat and SOCS box containing 11
chr3_+_24067387 2.96 ENSDART00000055609
atf4b
activating transcription factor 4b
chr8_-_38168395 2.60 ENSDART00000155189
pdlim2
PDZ and LIM domain 2 (mystique)
chr21_-_2147438 2.52 ENSDART00000172276
zgc:163077
zgc:163077
chr8_+_25880895 2.31 ENSDART00000124300
rhoab
ras homolog gene family, member Ab
chr21_+_25729090 2.27 ENSDART00000021664
cldnb
claudin b
chr11_-_5793 2.25

chr19_+_17451381 2.15 ENSDART00000167602
spaca4l
sperm acrosome associated 4 like
chr22_+_16471319 2.14 ENSDART00000014330
ier5
immediate early response 5
chr23_+_25930072 2.13 ENSDART00000124103
hnf4a
hepatocyte nuclear factor 4, alpha
chr25_-_18234069 2.10 ENSDART00000104496
dusp6
dual specificity phosphatase 6
chr20_+_30948175 1.93

chr4_+_56996802 1.81

chr11_-_11925832 1.78

chr23_+_116397 1.75

chr25_-_22089794 1.49 ENSDART00000139110
pkp3a
plakophilin 3a
chr14_-_40454194 1.42 ENSDART00000166621
ef1
E74-like factor 1 (ets domain transcription factor)
chr11_-_18649022 1.42

chr8_-_337744 1.39

chr16_-_31517906 1.36 ENSDART00000145691
ENSDARG00000054814
ENSDARG00000054814
chr6_-_47928548 1.29

chr19_-_7576069 1.25 ENSDART00000148836
rfx5
regulatory factor X, 5
chr13_-_3801122 1.24

chr19_-_19888074 1.20

chr4_-_71353374 1.20

chr5_-_30324182 1.20 ENSDART00000153909
spns2
spinster homolog 2 (Drosophila)
chr8_+_46319434 1.15 ENSDART00000145618
si:dkey-75a21.2
si:dkey-75a21.2
chr21_-_2147085 1.11 ENSDART00000169262
zgc:163077
zgc:163077
chr4_-_49071258 1.08 ENSDART00000162560
BX855613.1
ENSDARG00000098743
chr6_-_47928632 1.04

chr20_+_28465622 1.03 ENSDART00000146905
ENSDART00000103355
rhov
ras homolog family member V
chr20_-_26632676 1.01 ENSDART00000131994
mthfd1l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr5_+_23585492 1.00 ENSDART00000135083
tp53
tumor protein p53
chr4_-_6800721 0.99 ENSDART00000099467
ifrd1
interferon-related developmental regulator 1
chr16_+_42925950 0.94 ENSDART00000159730
ENSDART00000014956
polr3glb
polymerase (RNA) III (DNA directed) polypeptide G like b
chr17_+_28657998 0.94 ENSDART00000159067
hectd1
HECT domain containing 1
chr21_-_36338514 0.94 ENSDART00000157826
mpp1
membrane protein, palmitoylated 1
chr13_+_7243353 0.92 ENSDART00000146592
gbf1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr6_+_42478185 0.86 ENSDART00000150226
mst1ra
macrophage stimulating 1 receptor a
chr21_+_22808694 0.85 ENSDART00000065555
birc2
baculoviral IAP repeat containing 2
chr15_-_40391882 0.81

chr5_+_41680352 0.80 ENSDART00000142855
tbx6l
T-box 6, like
chr23_-_30119058 0.79 ENSDART00000103480
ccdc187
coiled-coil domain containing 187
chr14_-_5509554 0.75

KN149695v1_+_67009 0.74 ENSDART00000178024
ENSDARG00000107779
ENSDARG00000107779
chr4_-_75690772 0.73 ENSDART00000174183
CABZ01063884.1
ENSDARG00000105697
chr11_+_26152136 0.70

chr7_+_5408319 0.70 ENSDART00000142709
si:dkeyp-67a8.4
si:dkeyp-67a8.4
chr21_-_2222412 0.68 ENSDART00000169448
si:ch73-299h12.1
si:ch73-299h12.1
chr4_-_36838449 0.68

chr3_-_44113070 0.67 ENSDART00000160717
znf750
zinc finger protein 750
chr4_+_52851409 0.63

chr19_-_10962536 0.61 ENSDART00000160438
psmd4a
proteasome 26S subunit, non-ATPase 4a
chr3_+_30790513 0.60 ENSDART00000130422
cldni
claudin i
chr16_-_31517858 0.59 ENSDART00000145691
ENSDARG00000054814
ENSDARG00000054814
chr8_+_48976657 0.57 ENSDART00000008058
aak1a
AP2 associated kinase 1a
chr5_+_19506512 0.56 ENSDART00000047841
sgsm1a
small G protein signaling modulator 1a
chr7_+_38455040 0.55

chr5_+_40910195 0.53 ENSDART00000134317
vcp
valosin containing protein
chr8_+_48976994 0.52 ENSDART00000008058
aak1a
AP2 associated kinase 1a
chr20_+_25726978 0.51 ENSDART00000164264
ppat
phosphoribosyl pyrophosphate amidotransferase
chr5_+_15319430 0.51 ENSDART00000162003
hspb8
heat shock protein b8
chr21_-_36338704 0.50 ENSDART00000157826
mpp1
membrane protein, palmitoylated 1
chr23_+_25929969 0.49 ENSDART00000145426
hnf4a
hepatocyte nuclear factor 4, alpha
chr22_+_39098205 0.49 ENSDART00000002826
gmppb
GDP-mannose pyrophosphorylase B
chr7_+_23306546 0.47 ENSDART00000049885
si:dkey-172j4.3
si:dkey-172j4.3
chr13_+_35213326 0.46 ENSDART00000019323
jag1b
jagged 1b
chr13_+_1051015 0.46 ENSDART00000033528
tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr13_+_46487890 0.45

chr4_+_56143439 0.45 ENSDART00000178597
si:ch211-212k5.1
si:ch211-212k5.1
chr20_-_16649213 0.44 ENSDART00000137601
ches1
checkpoint suppressor 1
chr22_-_36718623 0.43

chr12_+_37005712 0.43

chr17_+_23536720 0.43 ENSDART00000143508
pank1a
pantothenate kinase 1a
chr9_-_12913920 0.42 ENSDART00000122799
ankzf1
ankyrin repeat and zinc finger domain containing 1
chr13_-_36996246 0.42 ENSDART00000133242
syne2b
spectrin repeat containing, nuclear envelope 2b
chr6_-_49064365 0.41 ENSDART00000156124
si:ch211-105j21.9
si:ch211-105j21.9
KN149946v1_-_12861 0.41 ENSDART00000163016
CABZ01048402.2
ENSDARG00000103875
chr3_+_19066717 0.40 ENSDART00000134433
il12rb2l
interleukin 12 receptor, beta 2a, like
chr25_+_29752909 0.40 ENSDART00000005299
hsd17b12a
hydroxysteroid (17-beta) dehydrogenase 12a
chr4_+_46414646 0.40 ENSDART00000179615
BX324155.2
ENSDARG00000107359
chr5_-_4082749 0.39

chr13_+_7243325 0.39 ENSDART00000146592
gbf1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr11_-_269181 0.39

KN149726v1_+_1094 0.37

chr14_+_50394381 0.36 ENSDART00000158329
tnip1
TNFAIP3 interacting protein 1
chr11_+_37639045 0.36 ENSDART00000111157
si:ch211-112f3.4
si:ch211-112f3.4
chr20_+_25726732 0.36 ENSDART00000078385
ppat
phosphoribosyl pyrophosphate amidotransferase
chr16_-_27609082 0.36

chr18_+_45680493 0.35 ENSDART00000109948
qser1
glutamine and serine rich 1
chr5_+_17120453 0.34

chr6_+_56157608 0.34 ENSDART00000149665
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr4_+_4825409 0.33 ENSDART00000150309
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr8_-_31597252 0.32 ENSDART00000018886
ghra
growth hormone receptor a
chr6_-_31380261 0.31

chr1_+_15827083 0.31

chr12_-_20493683 0.30

chr1_+_52365033 0.30 ENSDART00000133411
inpp4b
inositol polyphosphate-4-phosphatase type II B
chr18_+_21419735 0.28 ENSDART00000144523
necab2
N-terminal EF-hand calcium binding protein 2
chr25_-_10930008 0.28 ENSDART00000156846
mespbb
mesoderm posterior bb
chr14_+_6308806 0.28 ENSDART00000139292
si:dkeyp-44a8.2
si:dkeyp-44a8.2
chr19_-_19888009 0.28

chr16_+_13964949 0.28 ENSDART00000143983
zgc:174888
zgc:174888
chr3_-_16569378 0.27 ENSDART00000055859
pold1
polymerase (DNA directed), delta 1, catalytic subunit
chr8_+_48976926 0.27 ENSDART00000008058
aak1a
AP2 associated kinase 1a
chr14_-_25636795 0.27

KN150708v1_+_30684 0.26

chr7_-_29262814 0.26 ENSDART00000124028
anxa2b
annexin A2b
chr20_+_32575184 0.26 ENSDART00000145269
ostm1
osteopetrosis associated transmembrane protein 1
chr25_+_16215855 0.25 ENSDART00000064187
parvaa
parvin, alpha a
chr7_+_6786457 0.25 ENSDART00000172421
rbm14b
RNA binding motif protein 14b
chr5_-_62963536 0.24 ENSDART00000050865
surf4l
surfeit gene 4, like
chr20_+_49975268 0.24 ENSDART00000008808
hmbox1b
homeobox containing 1 b
chr2_-_23310316 0.23 ENSDART00000146014
sap130b
Sin3A-associated protein b
chr7_+_71262935 0.23 ENSDART00000100396
ppp1r15a
protein phosphatase 1, regulatory subunit 15A
chr7_-_25426346 0.23 ENSDART00000082620
dysf
dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
chr22_+_11505448 0.23 ENSDART00000113930
npb
neuropeptide B
chr5_+_37184963 0.23 ENSDART00000053511
myo1ca
myosin Ic, paralog a
chr22_+_9832516 0.23 ENSDART00000105942
si:dkey-253d23.3
si:dkey-253d23.3
chr5_-_19691538 0.22 ENSDART00000139675
dao.1
D-amino-acid oxidase, tandem duplicate 1
chr24_+_22195227 0.22

chr16_-_13927684 0.22 ENSDART00000146719
leng9
leukocyte receptor cluster (LRC) member 9
chr11_+_268997 0.22 ENSDART00000168188
mettl1
methyltransferase like 1
chr3_-_15584548 0.22 ENSDART00000137325
mvp
major vault protein
chr4_-_12782246 0.22 ENSDART00000058020
helb
helicase (DNA) B
chr20_-_40823307 0.21 ENSDART00000061261
cx43
connexin 43
chr18_+_13108810 0.21 ENSDART00000161153
GAN
gigaxonin
chr11_-_25223723 0.21 ENSDART00000014945
hcfc1a
host cell factor C1a
chr13_+_46899292 0.20

chr9_-_30560373 0.20 ENSDART00000079068
asb11
ankyrin repeat and SOCS box containing 11
chr9_-_2416300 0.20

chr13_-_24779651 0.20 ENSDART00000077775
kat6b
K(lysine) acetyltransferase 6B
chr25_+_29752983 0.19 ENSDART00000141167
hsd17b12a
hydroxysteroid (17-beta) dehydrogenase 12a
chr1_-_39622531 0.19

chr16_-_43090120 0.19 ENSDART00000155637
BX005234.1
ENSDARG00000097761
chr16_-_13927947 0.19 ENSDART00000144856
leng9
leukocyte receptor cluster (LRC) member 9
chr25_+_18487313 0.18 ENSDART00000148741
met
MET proto-oncogene, receptor tyrosine kinase
chr13_-_37523664 0.18 ENSDART00000115354
si:dkey-188i13.10
si:dkey-188i13.10
chr23_-_1008307 0.17 ENSDART00000110588
cdh26.1
cadherin 26, tandem duplicate 1
chr3_+_25933164 0.17 ENSDART00000143697
si:dkeyp-69e1.8
si:dkeyp-69e1.8
chr21_-_18787657 0.17

chr1_+_19376127 0.16 ENSDART00000088653
prss12
protease, serine, 12 (neurotrypsin, motopsin)
chr17_-_5426195 0.16 ENSDART00000035944
clic5a
chloride intracellular channel 5a
chr11_+_6118826 0.16 ENSDART00000159680
nr2f6b
nuclear receptor subfamily 2, group F, member 6b
KN149735v1_-_1679 0.16

chr21_+_26576104 0.16 ENSDART00000142667
esrra
estrogen-related receptor alpha
chr5_+_33949469 0.15 ENSDART00000136787
aif1l
allograft inflammatory factor 1-like
chr15_+_17407258 0.15 ENSDART00000111753
vmp1
vacuole membrane protein 1
chr3_-_39245184 0.15

chr23_-_9872524 0.15 ENSDART00000133602
mapre1b
microtubule-associated protein, RP/EB family, member 1b
chr12_-_36113358 0.15

chr10_+_35479226 0.15 ENSDART00000147303
hhla2a.1
HERV-H LTR-associating 2a, tandem duplicate 1
chr22_-_20551624 0.15

chr4_+_4825628 0.15 ENSDART00000150309
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr16_-_24916921 0.14 ENSDART00000153731
si:dkey-79d12.5
si:dkey-79d12.5
chr6_-_39313219 0.14

chr10_+_5693933 0.14 ENSDART00000159769
pam
peptidylglycine alpha-amidating monooxygenase
chr24_-_32750010 0.13 ENSDART00000038364
ca2
carbonic anhydrase II
chr9_+_22846535 0.13 ENSDART00000101765
si:dkey-189g17.2
si:dkey-189g17.2
chr3_+_24067430 0.12 ENSDART00000055609
atf4b
activating transcription factor 4b
chr22_-_36718332 0.12

chr21_-_11564398 0.12 ENSDART00000141297
cast
calpastatin
chr19_-_29706969 0.11 ENSDART00000130815
ENSDART00000172590
ENSDART00000103437
e2f3
E2F transcription factor 3
chr14_+_34146377 0.11 ENSDART00000131861
tmsb2
thymosin beta 2
chr8_-_11132386 0.11 ENSDART00000133532
ENSDARG00000078221
ENSDARG00000078221
chr6_+_49489473 0.11 ENSDART00000177749
FO704848.1
ENSDARG00000107438
chr21_-_7702431 0.10

chr8_-_39944817 0.10 ENSDART00000083066
asphd2
aspartate beta-hydroxylase domain containing 2
chr24_-_3273409 0.10

chr5_-_22981395 0.10 ENSDART00000170293
si:dkeyp-20g2.1
si:dkeyp-20g2.1
chr17_+_45430353 0.10 ENSDART00000162937
ezra
ezrin a
chr8_+_36522231 0.09 ENSDART00000126687
sf3a1
splicing factor 3a, subunit 1
chr4_-_22590638 0.09 ENSDART00000137814
hcls1
hematopoietic cell-specific Lyn substrate 1
chr25_+_9904821 0.09

chr17_-_49931552 0.09 ENSDART00000161008
filip1a
filamin A interacting protein 1a
chr13_+_21757676 0.08 ENSDART00000162709
ndst2a
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2a
chr4_+_5308883 0.08 ENSDART00000150366
si:ch211-214j24.10
si:ch211-214j24.10
chr14_-_33704021 0.08 ENSDART00000149396
ENSDART00000123607
cyfip2
cytoplasmic FMR1 interacting protein 2
chr8_-_36522230 0.08 ENSDART00000132804
ccdc157
coiled-coil domain containing 157
chr5_-_19619115 0.06 ENSDART00000026516
pxmp2
peroxisomal membrane protein 2
chr11_-_6004509 0.06 ENSDART00000108628
ano8b
anoctamin 8b
chr10_+_35478939 0.06 ENSDART00000147303
hhla2a.1
HERV-H LTR-associating 2a, tandem duplicate 1
chr23_+_39569262 0.06 ENSDART00000031616
mical1
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr1_-_22170553 0.06 ENSDART00000139412
SMIM18
small integral membrane protein 18
chr2_-_44893769 0.06 ENSDART00000041806
acsm3
acyl-CoA synthetase medium-chain family member 3
chr5_+_50306662 0.05 ENSDART00000149892
col4a3bpa
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr7_+_23604092 0.05 ENSDART00000101406
rab39bb
RAB39B, member RAS oncogene family b
chr21_-_44570264 0.05 ENSDART00000159323
fundc2
fun14 domain containing 2
chr13_+_46899421 0.04

chr24_-_36412892 0.04 ENSDART00000148868
coasy
CoA synthase
chr12_-_29118423 0.04 ENSDART00000153175
si:ch211-214e3.5
si:ch211-214e3.5
chr11_-_25223169 0.04

chr16_-_34330688 0.03 ENSDART00000044235
ENSDART00000159744
phactr4b
phosphatase and actin regulator 4b
chr21_+_10769107 0.03

chr1_-_18084246 0.03

chr12_+_23250339 0.03 ENSDART00000078896
waca
WW domain containing adaptor with coiled-coil a
chr3_+_16826320 0.03 ENSDART00000112450
cavin1a
caveolae associated protein 1a
chr4_+_4825461 0.03 ENSDART00000150309
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr23_-_1008468 0.02 ENSDART00000110588
cdh26.1
cadherin 26, tandem duplicate 1
chr5_+_23585615 0.02 ENSDART00000135083
tp53
tumor protein p53

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.7 2.1 GO:1905178 regulation of cardiac muscle tissue regeneration(GO:1905178)
0.5 2.3 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.3 1.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.3 1.0 GO:0071896 protein localization to adherens junction(GO:0071896)
0.2 0.8 GO:0010939 regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544)
0.2 2.6 GO:0070365 hepatocyte differentiation(GO:0070365)
0.2 0.5 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.2 1.0 GO:1901216 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.2 0.5 GO:0071947 protein K29-linked deubiquitination(GO:0035523) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) protein K33-linked deubiquitination(GO:1990168)
0.1 2.2 GO:0007286 spermatid development(GO:0007286)
0.1 1.4 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 2.9 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 1.0 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 0.6 GO:0006703 estrogen biosynthetic process(GO:0006703) estrogen metabolic process(GO:0008210)
0.1 0.8 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
0.1 0.5 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.2 GO:0050765 monocyte activation involved in immune response(GO:0002280) negative regulation of phagocytosis(GO:0050765)
0.1 0.3 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.1 1.1 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 0.2 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 1.3 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:0060416 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.2 GO:0070178 D-amino acid catabolic process(GO:0019478) D-serine catabolic process(GO:0036088) D-amino acid metabolic process(GO:0046416) D-serine metabolic process(GO:0070178)
0.1 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.3 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.5 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.6 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.3 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.0 0.3 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.2 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.9 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 1.5 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 0.4 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.0 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.2 GO:0033505 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0 0.2 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.3 GO:0071698 olfactory placode development(GO:0071698)
0.0 0.1 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.5 GO:0034620 cellular response to unfolded protein(GO:0034620)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.1 0.3 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 1.1 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 1.5 GO:0030057 desmosome(GO:0030057)
0.1 2.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 2.2 GO:0031941 filamentous actin(GO:0031941)
0.1 0.6 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.2 GO:0032420 stereocilium(GO:0032420)
0.0 2.9 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.9 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.3 0.9 GO:0004044 amidophosphoribosyltransferase activity(GO:0004044)
0.2 2.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 1.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 0.5 GO:0008905 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.1 2.6 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.3 GO:0004903 growth hormone receptor activity(GO:0004903)
0.1 2.2 GO:0004675 transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.1 0.6 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 0.2 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.1 0.8 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 2.0 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 1.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 2.9 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.3 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.1 GO:0016842 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) amidine-lyase activity(GO:0016842)
0.0 0.3 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 1.7 GO:0045296 cadherin binding(GO:0045296)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 3.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.2 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 1.2 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.4 GO:0019955 cytokine binding(GO:0019955)
0.0 1.1 GO:0019199 transmembrane receptor protein tyrosine kinase activity(GO:0004714) transmembrane receptor protein kinase activity(GO:0019199)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.7 GO:0019901 protein kinase binding(GO:0019901)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 2.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 1.3 PID CD40 PATHWAY CD40/CD40L signaling
0.1 1.3 PID ARF 3PATHWAY Arf1 pathway
0.1 1.0 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 2.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.0 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 3.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane