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Results for foxb1b+foxb2

Z-value: 1.44

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Transcription factors associated with foxb1b+foxb2

Gene Symbol Gene ID Gene Info
ENSDARG00000037475 forkhead box B2
ENSDARG00000053650 forkhead box B1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxb1bdr10_dc_chr7_+_29189933_29189974-0.581.9e-02Click!

Activity profile of foxb1b+foxb2 motif

Sorted Z-values of foxb1b+foxb2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of foxb1b+foxb2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_-_32636372 6.16 ENSDART00000085512
ENSDART00000144694
KN motif and ankyrin repeat domains 1b
chr8_+_37716781 5.20 ENSDART00000108556
nucleophosmin/nucleoplasmin, 2a
chr4_-_14208573 4.34 ENSDART00000015134
twinfilin actin-binding protein 1b
chr3_+_42383724 3.24

chr11_-_25019899 3.09 ENSDART00000123567
snail family zinc finger 1a
chr24_-_14446593 2.93

chr7_-_37283707 2.83 ENSDART00000148905
ENSDART00000150229
cylindromatosis (turban tumor syndrome), a
chr11_-_6442588 2.79 ENSDART00000137879
zgc:162969
chr14_-_7102535 2.75 ENSDART00000036463
DND microRNA-mediated repression inhibitor 1
chr24_-_20999883 2.59 ENSDART00000155652
GRAM domain containing 1c
chr7_+_45747622 2.45 ENSDART00000163991
cyclin E1
chr7_+_45747395 2.30 ENSDART00000163991
cyclin E1
chr5_-_21523599 2.28 ENSDART00000023306
ankyrin repeat and SOCS box-containing 12a
chr16_-_47446494 2.27 ENSDART00000032188
si:dkey-256h2.1
chr5_-_68011971 2.20 ENSDART00000141699
methylphosphate capping enzyme
chr16_-_25318413 2.11 ENSDART00000058943
ENSDARG00000040280
chr3_-_20944579 2.09 ENSDART00000153739
nemo-like kinase, type 1
chr3_+_25776714 2.02 ENSDART00000170324
target of myb1 membrane trafficking protein
chr14_+_14850200 2.01 ENSDART00000167966
zgc:158852
chr8_+_26015379 1.96 ENSDART00000142555
ariadne homolog 2 (Drosophila)
chr6_-_31377513 1.92 ENSDART00000145715
adenylate kinase 4
chr9_-_21677941 1.91 ENSDART00000121939
ENSDART00000080404
M-phase phosphoprotein 8
chr23_-_16755868 1.90 ENSDART00000020810
syndecan binding protein (syntenin) 2
chr5_+_36049836 1.89 ENSDART00000147667
alkB homolog 6
chr1_+_21244200 1.87 ENSDART00000087729
lysine (K)-specific demethylase 4C
chr25_-_7794186 1.83 ENSDART00000104686
autophagy/beclin-1 regulator 1b
chr17_+_43916865 1.82 ENSDART00000049503
pellino E3 ubiquitin protein ligase family member 2
chr19_+_32670271 1.82

chr2_-_54224744 1.81

chr24_+_26223767 1.81

chr6_+_11162062 1.79 ENSDART00000151548
SUMO1/sentrin/SMT3 specific peptidase 2
chr15_-_33342455 1.78

chr16_-_5205600 1.77 ENSDART00000148955
branched chain keto acid dehydrogenase E1, beta polypeptide
chr2_-_29939721 1.76 ENSDART00000031130
PAX interacting (with transcription-activation domain) protein 1
chr12_-_19063761 1.75 ENSDART00000153343
zinc finger CCCH-type containing 7B
chr23_-_1562572 1.74 ENSDART00000013635
F-box protein 30b
chr5_-_17372745 1.69 ENSDART00000141978
si:dkey-112e17.1
chr11_-_14044356 1.68 ENSDART00000085158
transmembrane protein 259
chr23_+_20586745 1.67 ENSDART00000157522
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr17_-_9806363 1.66 ENSDART00000021942
e2f-associated phosphoprotein
chr5_+_61136434 1.66 ENSDART00000113508
heterogeneous nuclear ribonucleoprotein U-like 1 like
chr17_+_31205274 1.64 ENSDART00000155580
coiled-coil domain containing 32
chr8_+_7655257 1.63 ENSDART00000170184
FYVE, RhoGEF and PH domain containing 1
chr19_+_32000438 1.62 ENSDART00000150910
geminin, DNA replication inhibitor
chr8_-_3974320 1.60 ENSDART00000159895
myotubularin related protein 3
chr18_+_14725283 1.59 ENSDART00000146128
URI1, prefoldin-like chaperone
chr7_-_8466131 1.52 ENSDART00000065488
testis expressed 261
chr9_-_3548174 1.51 ENSDART00000145043
ENSDART00000169586
ddb1 and cul4 associated factor 17
chr13_-_25711537 1.51 ENSDART00000015154
poly(A) polymerase gamma
chr25_+_30627892 1.50

chr25_+_30627755 1.50

chr18_-_5167807 1.50

chr11_-_25019298 1.48 ENSDART00000130477
ENSDART00000079578
snail family zinc finger 1a
chr23_+_44470297 1.46 ENSDART00000149842
methylphosphate capping enzyme
chr7_+_15197911 1.46 ENSDART00000046542
insulin-like growth factor 1b receptor
chr23_+_22052173 1.45 ENSDART00000087110
eukaryotic translation initiation factor 4 gamma, 3b
chr14_+_20941526 1.43 ENSDART00000138551
small integral membrane protein 19
chr16_-_25317921 1.42

chr15_-_5913264 1.42 ENSDART00000155156
ENSDART00000155971
si:ch73-281n10.2
chr20_-_53123124 1.42 ENSDART00000162812
farnesyl-diphosphate farnesyltransferase 1
chr3_-_20944854 1.41 ENSDART00000109790
nemo-like kinase, type 1
chr12_-_7201358 1.41 ENSDART00000048866
inositol polyphosphate multikinase b
chr2_-_48103519 1.41 ENSDART00000056305
frizzled class receptor 8b
chr25_-_28630138 1.40

chr22_-_21873054 1.37

chr24_+_12693997 1.37

chr5_-_47610384 1.35

chr14_-_6901209 1.35 ENSDART00000167994
ENSDART00000166532
storkhead box 2b
chr16_-_52090636 1.34 ENSDART00000155308
ENSDARG00000063300
chr22_-_4787016 1.34 ENSDART00000140313
tumor necrosis factor, alpha-induced protein 8-like 1
chr20_-_25587274 1.33 ENSDART00000141340
si:dkey-183n20.15
chr19_-_19452999 1.33 ENSDART00000163359
ENSDART00000167951
dynein, cytoplasmic 1, light intermediate chain 1
chr17_-_30635487 1.32 ENSDART00000154960
SH3 and SYLF domain containing 1
chr3_-_26060787 1.31 ENSDART00000113843
yippee-like 3
chr20_+_30476065 1.31 ENSDART00000062441
ribonuclease H1
chr1_+_53294559 1.29 ENSDART00000159900
centriole, cilia and spindle-associated protein a
chr23_+_22052045 1.29 ENSDART00000145172
eukaryotic translation initiation factor 4 gamma, 3b
chr21_-_25991445 1.28 ENSDART00000034875
stromal cell-derived factor 2
chr17_+_32408151 1.28 ENSDART00000155519
si:ch211-139d20.3
chr21_+_20350218 1.28 ENSDART00000144366
si:dkey-30k6.5
chr25_-_3091345 1.28 ENSDART00000032390
general transcription factor IIH, polypeptide 1
chr25_-_10694465 1.27 ENSDART00000127054
ENSDARG00000089303
chr22_-_35003371 1.26 ENSDART00000133537
Rho GTPase activating protein 19
chr8_+_7655310 1.26 ENSDART00000170184
FYVE, RhoGEF and PH domain containing 1
chr7_-_31346802 1.24 ENSDART00000111388
immunoglobulin superfamily, DCC subclass, member 3
chr7_+_66660882 1.24 ENSDART00000082664
SET binding factor 2
chr23_-_3815871 1.24 ENSDART00000137826
high mobility group AT-hook 1a
chr17_+_10592507 1.24 ENSDART00000097274
autophagy related 14
chr15_+_20054306 1.24 ENSDART00000155199
zgc:112083
chr13_+_40689102 1.23 ENSDART00000016960
protein kinase, cGMP-dependent, type Ia
chr24_+_19065679 1.23 ENSDART00000139299
zgc:162928
chr4_-_12782246 1.23 ENSDART00000058020
helicase (DNA) B
chr24_+_14095601 1.23 ENSDART00000124740
nuclear receptor coactivator 2
chr4_+_8669695 1.23 ENSDART00000168768
adiponectin receptor 2
chr10_-_39362315 1.22 ENSDART00000023831
cryptochrome circadian clock 5
chr19_+_5399535 1.22 ENSDART00000145749
si:dkeyp-113d7.1
chr21_-_25991335 1.21 ENSDART00000034875
stromal cell-derived factor 2
chr11_+_11136919 1.21 ENSDART00000026135
lymphocyte antigen 75
chr11_-_30261689 1.20 ENSDART00000101667
mitogen-activated protein kinase kinase kinase kinase 3a
chr5_-_66070385 1.20 ENSDART00000032909
K(lysine) acetyltransferase 5b
chr13_+_36554762 1.19 ENSDART00000136030
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s
chr25_-_7794262 1.19 ENSDART00000156761
autophagy/beclin-1 regulator 1b
chr3_+_13780104 1.18 ENSDART00000164179
synaptonemal complex central element protein 2
chr14_-_21816253 1.18 ENSDART00000113752
si:dkey-6i22.5
chr5_-_64432697 1.18 ENSDART00000165556
torsin family 2, member A
chr11_-_25495823 1.17 ENSDART00000171935
bromodomain and PHD finger containing, 3a
chr21_-_26369503 1.16 ENSDART00000137312
eukaryotic translation initiation factor 4E binding protein 3
chr6_-_43297126 1.16 ENSDART00000154170
FERM domain containing 4Ba
chr12_+_35855929 1.16

chr3_-_29837411 1.15 ENSDART00000139310
branched chain amino-acid transaminase 2, mitochondrial
chr12_+_47828020 1.15 ENSDART00000112010
leucine zipper, putative tumor suppressor 2b
chr25_-_25339397 1.14 ENSDART00000171589
v-Ha-ras Harvey rat sarcoma viral oncogene homolog a
chr8_+_10825036 1.14 ENSDART00000140717
bromodomain and PHD finger containing, 3b
chr16_-_26947117 1.14 ENSDART00000111156
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr21_+_3764216 1.14 ENSDART00000149777
senataxin
chr5_-_65564733 1.14 ENSDART00000178162
ENSDARG00000107190
chr12_+_30611399 1.14 ENSDART00000153036
solute carrier family 35, member F3a
chr21_-_25991595 1.14 ENSDART00000034875
stromal cell-derived factor 2
chr3_+_56882443 1.13

chr2_-_57826189 1.13 ENSDART00000131420
si:dkeyp-68b7.5
chr16_+_46443800 1.12 ENSDART00000131072
rapunzel 2
chr9_+_28329384 1.12 ENSDART00000046880
pleckstrin homology domain containing, family M, member 3
chr9_-_3548211 1.10 ENSDART00000145043
ENSDART00000169586
ddb1 and cul4 associated factor 17
chr7_-_8465929 1.09 ENSDART00000172928
testis expressed 261
chr16_-_25318334 1.09 ENSDART00000058943
ENSDARG00000040280
chr3_+_52745606 1.08 ENSDART00000104683
pre-B-cell leukemia transcription factor 4
chr16_+_41004372 1.08 ENSDART00000058587
glycogen synthase kinase binding protein
chr8_-_25696708 1.08 ENSDART00000007482
testis specific protein, Y-linked
chr6_-_52725402 1.07 ENSDART00000033949
oxidative stress responsive serine-rich 1
chr5_+_51979524 1.07 ENSDART00000168317
amyloid beta (A4) precursor protein-binding, family A, member 1a
chr7_+_59371957 1.07 ENSDART00000125570
tRNA methyltransferase 44 homolog (S. cerevisiae)
chr16_+_25381315 1.07 ENSDART00000114528
TBC1 domain family, member 31
chr18_+_5066229 1.07 ENSDART00000157671
ENSDARG00000100626
chr16_-_39317068 1.06 ENSDART00000133642
glycerol-3-phosphate dehydrogenase 1-like
chr8_+_7815256 1.06 ENSDART00000165575
CXXC finger protein 1a
chr4_-_14625618 1.06 ENSDART00000137847
plexin b2a
chr11_+_18450008 1.06 ENSDART00000162694
nuclear receptor coactivator 3
chr20_-_53123015 1.05 ENSDART00000162812
farnesyl-diphosphate farnesyltransferase 1
chr23_-_36349563 1.05

chr15_-_28547372 1.05 ENSDART00000057696
G protein-coupled receptor kinase interacting ArfGAP 1
chr13_-_36554590 1.04 ENSDART00000085298
L-2-hydroxyglutarate dehydrogenase
chr8_+_20108592 1.04

chr8_+_26015350 1.04 ENSDART00000004521
ariadne homolog 2 (Drosophila)
chr9_-_32347822 1.04 ENSDART00000037182
ankyrin repeat domain 44
chr12_+_38633026 1.04 ENSDART00000155563
ATP-binding cassette, sub-family A (ABC1), member 5
chr25_-_12316228 1.04 ENSDART00000168275
de-etiolated homolog 1 (Arabidopsis)
chr19_-_46500888 1.03 ENSDART00000178772
phosphatidylserine synthase 1b
chr8_-_17755104 1.03 ENSDART00000131276
si:ch211-150o23.2
chr12_+_18794467 1.03 ENSDART00000127536
chromobox homolog 7b
chr21_-_9689702 1.03 ENSDART00000158836
Rho GTPase activating protein 24
chr2_-_4191540 1.03 ENSDART00000158335
RAB18B, member RAS oncogene family
chr21_-_30247820 1.02 ENSDART00000066363
ENSDARG00000045127
chr13_+_24549249 1.02 ENSDART00000113981
zgc:66426
chr7_-_31669675 1.01 ENSDART00000131009
brain-derived neurotrophic factor
chr16_-_25318260 1.00 ENSDART00000058943
ENSDARG00000040280
chr19_+_7839888 1.00

chr17_-_9806413 0.99 ENSDART00000021942
e2f-associated phosphoprotein
chr10_-_24350114 0.98 ENSDART00000109549
ENSDART00000148480
inositol polyphosphate-5-phosphatase Kb
chr24_-_26224123 0.98 ENSDART00000080039
leucine rich repeat containing 31
chr5_+_61678410 0.98 ENSDART00000074117
aspartoacylase
chr3_+_13780013 0.97 ENSDART00000164179
synaptonemal complex central element protein 2
chr24_-_6649190 0.97 ENSDART00000042478
enkurin, TRPC channel interacting protein
chr6_-_19556029 0.97 ENSDART00000136019
protein phosphatase 1, regulatory subunit 12C
chr20_+_34485425 0.97 ENSDART00000146924
tRNA methyltransferase 1-like
chr13_-_22772577 0.97 ENSDART00000089133
RUN and FYVE domain containing 2
chr8_-_25696852 0.97 ENSDART00000007482
testis specific protein, Y-linked
chr7_-_31346844 0.96 ENSDART00000111388
immunoglobulin superfamily, DCC subclass, member 3
chr23_+_38313746 0.96 ENSDART00000129593
zinc finger protein 217
chr13_+_36832090 0.96 ENSDART00000024386
FERM domain containing 6
chr1_+_21244242 0.96 ENSDART00000087729
lysine (K)-specific demethylase 4C
chr6_-_49802414 0.96 ENSDART00000008959
negative elongation factor complex member C/D
chr8_-_50899562 0.96 ENSDART00000053750
acyl-CoA synthetase long-chain family member 2
chr15_+_27000467 0.96 ENSDART00000023842
protein phosphatase, Mg2+/Mn2+ dependent, 1Da
chr7_+_52437748 0.95 ENSDART00000174061
ENSDART00000174094
ENSDART00000110906
ENSDART00000174238
ENSDART00000174071
zinc finger protein 280D
chr23_-_30837726 0.95 ENSDART00000075918
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr21_+_15505169 0.95 ENSDART00000011318
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b
chr15_+_19948916 0.95 ENSDART00000054416
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, b
chr20_+_27813565 0.95 ENSDART00000008306
zinc finger and BTB domain containing 1
chr21_-_32048130 0.95 ENSDART00000137878
methionine adenosyltransferase II, beta
chr21_-_30247560 0.95 ENSDART00000066363
ENSDARG00000045127
chr23_+_28213261 0.95 ENSDART00000143362
ENSDARG00000094837
chr14_+_7596207 0.94 ENSDART00000113299
zgc:110843
chr5_-_31889551 0.94 ENSDART00000168870
G protein-coupled receptor 107
chr24_-_6649248 0.94 ENSDART00000042478
enkurin, TRPC channel interacting protein
chr10_-_8839096 0.94 ENSDART00000080763
si:dkey-27b3.2
chr2_+_34128846 0.94 ENSDART00000056666
kelch-like family member 20
chr10_-_24350023 0.93 ENSDART00000109549
ENSDART00000148480
inositol polyphosphate-5-phosphatase Kb
chr15_+_19948869 0.93 ENSDART00000054416
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, b
chr19_+_40750511 0.93 ENSDART00000147391
family with sequence similarity 133, member B
chr17_-_23234771 0.92

chr14_+_27811681 0.91

chr16_-_37518912 0.91

chr2_-_24413154 0.91 ENSDART00000145526
solute carrier family 12 (potassium/chloride transporter), member 7a
chr4_+_11203919 0.91 ENSDART00000150551
ENSDARG00000096218
chr19_-_10996809 0.91 ENSDART00000163179
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a
chr5_-_48028931 0.91 ENSDART00000031194
LysM, putative peptidoglycan-binding, domain containing 3
chr23_-_18851683 0.91 ENSDART00000169180
ENSDART00000006482
transient receptor potential cation channel, subfamily C, member 4 associated protein b
chr23_+_28213293 0.91 ENSDART00000143362
ENSDARG00000094837
chr20_-_223222 0.91 ENSDART00000104790
zinc finger protein 292b
chr15_-_17088606 0.90 ENSDART00000154719
ENSDART00000014465
huntingtin interacting protein 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.6 2.8 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.5 2.7 GO:0070874 negative regulation of peptidyl-serine phosphorylation(GO:0033137) negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.5 5.7 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.5 2.0 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.5 1.5 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.5 3.7 GO:0070266 necroptotic process(GO:0070266) protein linear deubiquitination(GO:1990108)
0.4 2.2 GO:1904869 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.4 1.2 GO:0009098 leucine biosynthetic process(GO:0009098)
0.4 2.5 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.3 1.9 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.3 1.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.3 2.0 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.3 0.9 GO:0035092 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.3 1.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.3 2.5 GO:0007130 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.3 0.8 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.3 1.0 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.3 0.8 GO:0070841 inclusion body assembly(GO:0070841) regulation of inclusion body assembly(GO:0090083)
0.2 1.9 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.2 1.1 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.2 2.4 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.2 1.1 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.2 0.6 GO:0043476 pigment accumulation(GO:0043476)
0.2 1.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.2 1.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 5.4 GO:0008078 mesodermal cell migration(GO:0008078)
0.2 0.5 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.2 1.4 GO:0051013 microtubule severing(GO:0051013)
0.2 0.5 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) hepatic duct development(GO:0061011)
0.2 0.9 GO:0032790 ribosome disassembly(GO:0032790)
0.2 0.5 GO:0042126 nitrate metabolic process(GO:0042126) nitrate assimilation(GO:0042128)
0.1 0.7 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.1 1.0 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.3 GO:0048569 post-embryonic organ development(GO:0048569)
0.1 1.1 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.1 2.4 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 0.6 GO:0045190 B cell activation involved in immune response(GO:0002312) isotype switching(GO:0045190)
0.1 0.6 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.5 GO:0050746 regulation of lipoprotein metabolic process(GO:0050746) regulation of protein lipidation(GO:1903059)
0.1 1.6 GO:0016926 protein desumoylation(GO:0016926)
0.1 1.0 GO:0034389 lipid particle organization(GO:0034389)
0.1 6.5 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.1 1.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 1.6 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.1 0.9 GO:0006108 malate metabolic process(GO:0006108)
0.1 1.3 GO:0007584 response to nutrient(GO:0007584)
0.1 1.6 GO:0090169 regulation of spindle assembly(GO:0090169) regulation of mitotic spindle assembly(GO:1901673)
0.1 0.7 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 2.1 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 1.4 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.5 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.1 0.9 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 1.6 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.7 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 3.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 1.0 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 0.4 GO:0006498 N-terminal protein lipidation(GO:0006498) N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.1 0.6 GO:0009651 hypotonic response(GO:0006971) response to salt stress(GO:0009651) hypotonic salinity response(GO:0042539) sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 4.0 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.1 0.5 GO:0035794 positive regulation of mitochondrial membrane permeability(GO:0035794) mitochondrial outer membrane permeabilization(GO:0097345) positive regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902110) mitochondrial outer membrane permeabilization involved in programmed cell death(GO:1902686)
0.1 0.6 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 0.7 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 0.6 GO:1900045 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.7 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.5 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 2.1 GO:0046847 filopodium assembly(GO:0046847)
0.1 0.4 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 8.9 GO:0006338 chromatin remodeling(GO:0006338)
0.1 1.4 GO:0034112 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 0.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 0.9 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 0.8 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 1.5 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.1 0.7 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.1 0.9 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.3 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 1.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 1.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.3 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.1 0.4 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 3.2 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 2.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 1.0 GO:0097194 execution phase of apoptosis(GO:0097194)
0.1 0.7 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.3 GO:0031061 bulbus arteriosus development(GO:0003232) negative regulation of histone methylation(GO:0031061)
0.1 1.7 GO:0001895 retina homeostasis(GO:0001895)
0.1 0.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.6 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 1.5 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.1 GO:0035494 regulation of synaptic vesicle priming(GO:0010807) SNARE complex disassembly(GO:0035494)
0.0 0.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.7 GO:0006298 mismatch repair(GO:0006298)
0.0 0.2 GO:0035627 ceramide transport(GO:0035627)
0.0 0.4 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 2.1 GO:0009615 response to virus(GO:0009615)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 1.7 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.2 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 1.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 1.2 GO:0006400 tRNA modification(GO:0006400)
0.0 0.6 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 2.8 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.6 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.3 GO:0050670 regulation of mononuclear cell proliferation(GO:0032944) regulation of T cell proliferation(GO:0042129) regulation of lymphocyte proliferation(GO:0050670) regulation of leukocyte proliferation(GO:0070663)
0.0 0.6 GO:0051307 meiotic chromosome separation(GO:0051307)
0.0 1.2 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.4 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 2.0 GO:0055113 epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.0 0.8 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.8 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 1.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 1.0 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 1.3 GO:0016573 histone acetylation(GO:0016573)
0.0 0.2 GO:0008272 sulfate transport(GO:0008272)
0.0 1.4 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 2.4 GO:0007626 locomotory behavior(GO:0007626)
0.0 2.6 GO:0032870 cellular response to hormone stimulus(GO:0032870)
0.0 0.8 GO:0006282 regulation of DNA repair(GO:0006282)
0.0 0.1 GO:0035188 hatching(GO:0035188) hatching gland development(GO:0048785) organism emergence from protective structure(GO:0071684)
0.0 0.9 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.7 GO:0000154 rRNA modification(GO:0000154)
0.0 0.2 GO:0019856 pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.6 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.5 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 0.5 GO:0048599 oocyte development(GO:0048599)
0.0 0.8 GO:0048916 posterior lateral line development(GO:0048916)
0.0 0.9 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.4 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.3 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 1.2 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.3 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.7 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 0.6 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.3 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.6 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.4 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.5 GO:0007281 germ cell development(GO:0007281)
0.0 0.4 GO:0032543 mitochondrial translation(GO:0032543)
0.0 1.1 GO:0006413 translational initiation(GO:0006413)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026) positive regulation of mRNA processing(GO:0050685)
0.0 0.1 GO:0030042 actin filament depolymerization(GO:0030042)
0.0 0.9 GO:0008284 positive regulation of cell proliferation(GO:0008284)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0000801 central element(GO:0000801)
0.6 3.8 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.4 1.2 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.3 2.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.3 1.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.2 1.3 GO:0000439 core TFIIH complex(GO:0000439)
0.2 1.6 GO:0005899 insulin receptor complex(GO:0005899)
0.2 0.9 GO:0070695 FHF complex(GO:0070695)
0.2 0.9 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.2 1.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 2.4 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 5.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 2.1 GO:0044545 NSL complex(GO:0044545)
0.1 0.6 GO:0030897 HOPS complex(GO:0030897)
0.1 0.7 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 0.4 GO:0034990 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 2.8 GO:0043186 P granule(GO:0043186)
0.1 3.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 0.8 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 1.0 GO:0032021 NELF complex(GO:0032021)
0.1 1.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.7 GO:0072487 MSL complex(GO:0072487)
0.1 0.3 GO:0070390 transcription export complex 2(GO:0070390)
0.1 1.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 2.1 GO:0032587 ruffle membrane(GO:0032587)
0.1 2.2 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.0 GO:0035060 brahma complex(GO:0035060)
0.1 0.7 GO:0000812 Swr1 complex(GO:0000812)
0.1 1.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.5 GO:0072379 ER membrane insertion complex(GO:0072379)
0.1 1.0 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.6 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 2.7 GO:0001726 ruffle(GO:0001726)
0.1 0.7 GO:0032300 mismatch repair complex(GO:0032300)
0.1 3.4 GO:0030496 midbody(GO:0030496)
0.1 1.2 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.6 GO:0035869 ciliary transition zone(GO:0035869)
0.1 0.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.0 GO:0070822 Sin3-type complex(GO:0070822)
0.1 1.0 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 3.2 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 1.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.5 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 3.6 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.0 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 1.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.1 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 1.7 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 7.0 GO:0005730 nucleolus(GO:0005730)
0.0 4.1 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.8 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.5 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 4.1 GO:0005815 microtubule organizing center(GO:0005815)
0.0 0.4 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.2 GO:0000784 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.0 0.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.1 GO:0005741 mitochondrial outer membrane(GO:0005741)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.4 GO:0051059 NF-kappaB binding(GO:0051059)
1.1 3.2 GO:0097020 COPII adaptor activity(GO:0097020)
0.8 2.5 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.8 2.4 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.7 2.2 GO:0045545 syndecan binding(GO:0045545)
0.7 2.7 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.6 2.3 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.5 1.6 GO:0019807 aspartoacylase activity(GO:0019807)
0.5 3.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.5 5.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.4 1.2 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.4 1.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.4 1.5 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.4 4.3 GO:0003785 actin monomer binding(GO:0003785)
0.4 1.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.3 3.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.3 1.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 0.9 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.3 2.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.3 0.9 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.3 0.8 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.3 0.8 GO:0048270 methionine adenosyltransferase regulator activity(GO:0048270)
0.2 0.7 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.2 1.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 2.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 0.7 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.2 2.4 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.2 1.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.2 0.6 GO:0043515 kinetochore binding(GO:0043515)
0.2 1.0 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.2 1.4 GO:0001727 lipid kinase activity(GO:0001727)
0.2 1.0 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.2 1.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 1.6 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.2 0.6 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.2 0.6 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692) cGMP binding(GO:0030553)
0.2 1.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 0.7 GO:0070568 guanylyltransferase activity(GO:0070568)
0.2 0.5 GO:0046857 nitrite reductase [NAD(P)H] activity(GO:0008942) oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor(GO:0046857)
0.2 0.5 GO:0046592 polyamine oxidase activity(GO:0046592)
0.1 0.7 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.6 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.6 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 0.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.9 GO:0016504 peptidase activator activity(GO:0016504)
0.1 2.8 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.7 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 1.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.4 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.1 1.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.6 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.8 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.1 GO:0043142 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 3.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.4 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.7 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.9 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 0.2 GO:0102344 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1 1.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 0.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.6 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 1.1 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.7 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.7 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.1 0.3 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.6 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.4 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.2 GO:0046624 ceramide transporter activity(GO:0035620) sphingolipid transporter activity(GO:0046624) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 0.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.8 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.1 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 0.5 GO:0070628 proteasome binding(GO:0070628)
0.1 1.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 1.3 GO:0071949 FAD binding(GO:0071949)
0.0 1.0 GO:0000339 RNA cap binding(GO:0000339)
0.0 7.0 GO:0042393 histone binding(GO:0042393)
0.0 0.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 4.2 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 0.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 2.0 GO:0030276 clathrin binding(GO:0030276)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 1.8 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 1.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 2.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 1.9 GO:0005319 lipid transporter activity(GO:0005319)
0.0 2.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.9 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.8 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.8 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.6 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.8 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 2.3 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 1.0 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 1.0 GO:0042803 protein homodimerization activity(GO:0042803)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 3.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 3.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 0.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 1.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 1.8 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 4.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.8 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 2.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 2.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 0.6 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.1 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.6 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 1.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.7 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.0 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 5.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.9 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.1 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1