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DANIO-CODE
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Results for foxd3
Z-value: 1.97
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Transcription factors associated with foxd3
Network of associatons between targets according to the STRING database.
First level regulatory network of foxd3
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_-_32914487 Show fit | 5.44 |
ENSDART00000015547
|
claudin g |
|
| chr5_+_36168475 Show fit | 5.13 |
ENSDART00000146854
|
MAP/microtubule affinity-regulating kinase 4a |
|
| chr15_+_38397772 Show fit | 5.03 |
ENSDART00000142403
|
si:dkey-24p1.6 |
|
| chr5_+_57254393 Show fit | 5.00 |
ENSDART00000050949
|
B-cell translocation gene 4 |
|
| chr17_+_14957568 Show fit | 4.17 |
ENSDART00000066604
|
G protein-coupled receptor 137c |
|
| chr4_-_16639774 Show fit | 3.97 |
ENSDART00000125323
|
caprin family member 2 |
|
| chr12_-_28680035 Show fit | 3.73 |
ENSDART00000020667
|
oxysterol binding protein-like 7 |
|
| chr10_+_15644868 Show fit | 3.60 |
ENSDART00000139259
|
zinc finger, AN1-type domain 5b |
|
| chr7_-_47978449 Show fit | 3.58 |
ENSDART00000127007
ENSDART00000024062 |
cytoplasmic polyadenylation element binding protein 1b |
|
| chr7_-_47990610 Show fit | 3.52 |
ENSDART00000147968
|
RNA binding protein with multiple splicing 2b |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 14.3 | GO:0051603 | proteolysis involved in cellular protein catabolic process(GO:0051603) |
| 0.8 | 7.6 | GO:0060281 | regulation of oocyte development(GO:0060281) |
| 1.0 | 7.3 | GO:0090244 | Wnt signaling pathway involved in somitogenesis(GO:0090244) |
| 1.0 | 6.7 | GO:2000479 | regulation of cAMP-dependent protein kinase activity(GO:2000479) negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.5 | 6.3 | GO:0019747 | regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052) |
| 0.2 | 6.3 | GO:0043297 | apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830) |
| 0.0 | 5.8 | GO:0016567 | protein ubiquitination(GO:0016567) |
| 0.6 | 5.7 | GO:0046548 | retinal rod cell development(GO:0046548) |
| 0.3 | 4.8 | GO:0046716 | muscle cell cellular homeostasis(GO:0046716) |
| 0.2 | 4.8 | GO:0045324 | late endosome to vacuole transport(GO:0045324) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 16.6 | GO:0005764 | lysosome(GO:0005764) |
| 0.0 | 10.7 | GO:0005730 | nucleolus(GO:0005730) |
| 0.2 | 9.3 | GO:0005814 | centriole(GO:0005814) |
| 0.2 | 9.1 | GO:0000779 | condensed chromosome, centromeric region(GO:0000779) |
| 0.1 | 7.8 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.7 | 7.3 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.2 | 6.5 | GO:0030496 | midbody(GO:0030496) |
| 0.1 | 5.8 | GO:0070160 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
| 0.5 | 5.1 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.1 | 4.7 | GO:0000118 | histone deacetylase complex(GO:0000118) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 15.5 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.1 | 11.1 | GO:0042393 | histone binding(GO:0042393) |
| 0.1 | 11.0 | GO:0042802 | identical protein binding(GO:0042802) |
| 0.0 | 7.5 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
| 0.5 | 6.9 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 1.0 | 6.7 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.6 | 6.5 | GO:0001217 | bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217) |
| 0.1 | 6.3 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.2 | 5.3 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.3 | 5.1 | GO:0015248 | sterol transporter activity(GO:0015248) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 9.0 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.2 | 6.5 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 6.4 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.3 | 4.4 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 3.7 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.1 | 3.3 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 3.1 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.1 | 2.8 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.1 | 2.3 | PID ATM PATHWAY | ATM pathway |
| 0.1 | 1.9 | PID FOXO PATHWAY | FoxO family signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 10.1 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.4 | 7.4 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.1 | 5.4 | REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 | Genes involved in Autodegradation of the E3 ubiquitin ligase COP1 |
| 0.2 | 4.4 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.2 | 3.6 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.4 | 3.4 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.1 | 2.8 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.1 | 2.8 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.1 | 2.5 | REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT | Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat |
| 0.1 | 2.4 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |