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Results for foxd3

Z-value: 1.97

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Transcription factors associated with foxd3

Gene Symbol Gene ID Gene Info
ENSDARG00000021032 forkhead box D3

Activity profile of foxd3 motif

Sorted Z-values of foxd3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of foxd3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_32914487 5.44 ENSDART00000015547
claudin g
chr5_+_36168475 5.13 ENSDART00000146854
MAP/microtubule affinity-regulating kinase 4a
chr15_+_38397772 5.03 ENSDART00000142403
si:dkey-24p1.6
chr5_+_57254393 5.00 ENSDART00000050949
B-cell translocation gene 4
chr17_+_14957568 4.17 ENSDART00000066604
G protein-coupled receptor 137c
chr4_-_16639774 3.97 ENSDART00000125323
caprin family member 2
chr12_-_28680035 3.73 ENSDART00000020667
oxysterol binding protein-like 7
chr10_+_15644868 3.60 ENSDART00000139259
zinc finger, AN1-type domain 5b
chr7_-_47978449 3.58 ENSDART00000127007
ENSDART00000024062
cytoplasmic polyadenylation element binding protein 1b
chr7_-_47990610 3.52 ENSDART00000147968
RNA binding protein with multiple splicing 2b
chr1_-_7160294 3.50 ENSDART00000174972
ENSDARG00000108483
chr22_-_28828375 3.46 ENSDART00000104880
ENSDART00000005112
si:dkeyp-34c12.1
chr12_+_28774063 3.44 ENSDART00000166229
phosphorylase kinase, gamma 2 (testis)
chr24_+_36429525 3.33 ENSDART00000062722
pseudouridylate synthase 3
chr1_-_50395003 3.21 ENSDART00000035150
spastin
chr12_-_22116694 3.19 ENSDART00000038310
ENSDART00000132731
ORMDL sphingolipid biosynthesis regulator 3
chr9_+_55731780 3.16 ENSDART00000111111
neuroligin 4b
chr11_+_17849608 3.15 ENSDART00000020283
RNA pseudouridylate synthase domain containing 4
chr2_+_30013086 3.08 ENSDART00000138050
RNA binding motif protein 33b
chr7_-_51497945 3.07 ENSDART00000054591
bone morphogenetic protein 15
chr15_+_20054306 3.06 ENSDART00000155199
zgc:112083
chr22_+_24532560 3.00 ENSDART00000169847
WD repeat domain 47b
chr16_-_47446494 2.92 ENSDART00000032188
si:dkey-256h2.1
chr19_-_27093095 2.88

chr10_-_14971273 2.84 ENSDART00000137430
SMAD family member 2
chr8_+_37716781 2.80 ENSDART00000108556
nucleophosmin/nucleoplasmin, 2a
chr22_-_10562118 2.78 ENSDART00000105846
si:dkey-42i9.8
chr2_-_44924505 2.76 ENSDART00000113351
non-SMC condensin I complex, subunit D2
chr16_+_25344257 2.74 ENSDART00000058938
F-box protein 32
chr1_-_7160099 2.70 ENSDART00000174972
ENSDARG00000108483
chr18_+_2250457 2.67

chr10_+_19059739 2.67 ENSDART00000038674
transmembrane protein 230a
chr4_+_14983045 2.65 ENSDART00000067046
cation/H+ exchanger protein 1
chr4_-_20414881 2.65 ENSDART00000161343
centrosomal protein 83
chr5_-_8712114 2.64 ENSDART00000134896
ENSDART00000147000
low-density lipoprotein receptor related-protein 13
chr20_+_48631807 2.62 ENSDART00000108884
PR domain containing 1c, with ZNF domain
chr19_+_5399535 2.57 ENSDART00000145749
si:dkeyp-113d7.1
chr3_+_17562348 2.57

chr22_+_24532479 2.57 ENSDART00000169847
WD repeat domain 47b
chr16_+_47283253 2.48 ENSDART00000062507
islet cell autoantigen 1
chr20_+_13987091 2.46 ENSDART00000152611
NIMA-related kinase 2
chr2_-_39026651 2.45 ENSDART00000114085
si:ch211-119o8.6
chr19_-_6274169 2.44 ENSDART00000140347
ENSDART00000092656
Ets2 repressor factor
chr2_+_22984662 2.43 ENSDART00000144890
BCL2-related ovarian killer b
chr15_-_17163526 2.43 ENSDART00000101724
v-mos Moloney murine sarcoma viral oncogene homolog
chr17_+_23463072 2.42

chr18_+_15303434 2.39 ENSDART00000099777
ENSDART00000170246
si:dkey-103i16.6
chr23_+_25952724 2.36 ENSDART00000124963
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr3_-_34398743 2.34 ENSDART00000023039
septin 9a
KN150339v1_-_39357 2.34 ENSDART00000169638
wu:fa19b12
chr6_-_53049946 2.33 ENSDART00000103267
family with sequence similarity 212, member Ab
chr22_+_18840143 2.33

chr19_+_16159980 2.31 ENSDART00000151169
glucocorticoid modulatory element binding protein 1
chr12_+_18784456 2.30 ENSDART00000105854
Josephin domain containing 1
chr5_+_60677040 2.30 ENSDART00000009507
GATS protein-like 2
chr2_+_34984631 2.29 ENSDART00000141796
astrotactin 1
chr10_+_37457234 2.26 ENSDART00000136554
A kinase (PRKA) anchor protein 1a
chr16_+_25693740 2.26 ENSDART00000077484
zinc fingers and homeoboxes 2a
chr16_+_36794614 2.25 ENSDART00000139069
2,4-dienoyl CoA reductase 1, mitochondrial
chr24_+_9887575 2.25 ENSDART00000172773
si:ch211-146l10.8
chr15_+_21776031 2.23 ENSDART00000136151
zgc:162339
chr15_+_38397715 2.22 ENSDART00000142403
si:dkey-24p1.6
chr16_+_19831573 2.22 ENSDART00000135359
metastasis associated in colon cancer 1
chr20_-_6542402 2.21 ENSDART00000054653
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like
chr19_-_48346883 2.21 ENSDART00000123771
ENSDART00000081675
catenin, beta 2
KN150663v1_-_3381 2.20

chr11_-_10001506 2.19 ENSDART00000123359
neuroligin 1
chr4_+_1770595 2.19 ENSDART00000148486
SR-related CTD-associated factor 11
chr5_-_15971338 2.19 ENSDART00000110437
piwi-like RNA-mediated gene silencing 2
chr18_+_17545564 2.18 ENSDART00000061007
metallothionein 2
chr24_-_20225190 2.17 ENSDART00000109223
deleted in lung and esophageal cancer 1
chr5_-_8712068 2.13 ENSDART00000134896
ENSDART00000147000
low-density lipoprotein receptor related-protein 13
chr20_-_28897936 2.13 ENSDART00000049462
RAB15, member RAS oncogene family
chr8_+_8605240 2.12 ENSDART00000075624
ubiquitin specific peptidase 11
chr12_+_30389706 2.10

chr15_-_14102102 2.09 ENSDART00000139068
zgc:114130
chr17_-_23689233 2.09 ENSDART00000124661
3'-phosphoadenosine 5'-phosphosulfate synthase 2a
chr19_-_35408237 2.07 ENSDART00000141704
si:rp71-45k5.2
chr15_-_43996427 2.05 ENSDART00000177294
ENSDART00000177892
ENSDART00000174655
ENSDARG00000106999
chr3_-_29779725 2.05 ENSDART00000151501
RUN domain containing 1
chr2_-_40857927 2.05 ENSDART00000157099
ENSDARG00000096869
chr23_+_45177338 2.04

chr8_+_40463218 2.01

chr14_-_32467474 2.00

chr6_+_40925259 2.00 ENSDART00000002728
ENSDART00000145153
eukaryotic translation initiation factor 4E nuclear import factor 1
chr6_-_53145464 1.97 ENSDART00000079694
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
chr23_-_35384257 1.96 ENSDART00000113643
F-box protein 25
chr16_+_25693878 1.96 ENSDART00000077484
zinc fingers and homeoboxes 2a
chr19_+_29716509 1.96 ENSDART00000142694
ENSDART00000009149
transmembrane protein 57a
chr3_-_28371648 1.95 ENSDART00000150912
ENSDARG00000096347
chr9_-_51745361 1.94 ENSDART00000154959
ENSDARG00000097096
chr12_+_20569459 1.92 ENSDART00000112847
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1, tandem duplicate 2
chr5_-_47419494 1.90 ENSDART00000078401
transmembrane protein 161B
chr15_-_8787051 1.89 ENSDART00000154171
Rho GTPase activating protein 35a
chr19_-_41820114 1.88 ENSDART00000038038
split hand/foot malformation (ectrodactyly) type 1
chr3_-_29779598 1.87 ENSDART00000151501
RUN domain containing 1
chr16_-_41537827 1.86 ENSDART00000169312
CKLF-like MARVEL transmembrane domain containing 6
chr9_-_8916860 1.83 ENSDART00000138527
RAB20, member RAS oncogene family
chr23_+_25952913 1.81 ENSDART00000124963
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr19_+_29716557 1.80 ENSDART00000142694
ENSDART00000009149
transmembrane protein 57a
chr5_-_21523599 1.80 ENSDART00000023306
ankyrin repeat and SOCS box-containing 12a
chr5_-_22466262 1.79 ENSDART00000172549
si:dkey-237j10.2
chr14_-_7437682 1.79 ENSDART00000172215
si:ch211-39i2.2
chr3_+_30187036 1.79 ENSDART00000151006
ENSDARG00000096295
chr12_-_10438255 1.78 ENSDART00000106172
ras-related C3 botulinum toxin substrate 1a (rho family, small GTP binding protein Rac1)
chr1_+_32825950 1.76 ENSDART00000018472
charged multivesicular body protein 2Bb
chr14_-_34293596 1.75 ENSDART00000128869
actin filament associated protein 1-like 1a
chr22_-_10722533 1.75 ENSDART00000081191
SAS-6 centriolar assembly protein
chr1_+_50547385 1.74 ENSDART00000132141
BTB (POZ) domain containing 3a
chr20_-_28898117 1.73 ENSDART00000049462
RAB15, member RAS oncogene family
chr15_+_23721725 1.72 ENSDART00000078336
kinesin light chain 3
chr6_-_39220951 1.72 ENSDART00000133305
ENSDART00000166290
osteosarcoma amplified 9, endoplasmic reticulum lectin
chr24_+_12873142 1.71 ENSDART00000142457
staufen double-stranded RNA binding protein 2
chr12_-_17741377 1.71 ENSDART00000166604
BAI1-associated protein 2-like 1a
chr3_-_42949449 1.71 ENSDART00000161127
axin 1
chr5_+_12971972 1.70 ENSDART00000132406
cyclin and CBS domain divalent metal cation transport mediator 4b
chr13_+_8364704 1.70 ENSDART00000109059
tetratricopeptide repeat domain 7A
chr12_-_25288550 1.69 ENSDART00000142674
zinc finger protein 36, C3H type-like 2
chr8_-_602656 1.69

chr11_+_24756894 1.68 ENSDART00000129211
ENSDARG00000044874
chr2_-_56897037 1.68 ENSDART00000164086
solute carrier family 25, member 42
chr9_-_38213786 1.67

chr18_+_27095471 1.67 ENSDART00000125326
ENSDART00000098334
protein phosphatase 1, regulatory subunit 15B
chr18_+_47305642 1.67 ENSDART00000009775
RNA binding motif protein 7
chr7_-_49528331 1.66 ENSDART00000052083
four jointed box 1
chr16_+_47283374 1.65 ENSDART00000062507
islet cell autoantigen 1
chr20_+_39145226 1.65 ENSDART00000142778
ENSDARG00000092980
chr17_+_32670368 1.64 ENSDART00000142449
cathepsin Ba
chr16_-_26654610 1.62 ENSDART00000134448
l(3)mbt-like 1b (Drosophila)
chr5_-_56254482 1.62 ENSDART00000014028
protein phosphatase, Mg2+/Mn2+ dependent, 1Db
chr14_-_26167494 1.62 ENSDART00000143454
ENSDART00000111860
synovial apoptosis inhibitor 1, synoviolin
chr17_-_29253770 1.62 ENSDART00000104219
REST corepressor 1
chr23_+_25952958 1.62 ENSDART00000124963
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr1_+_45148002 1.61 ENSDART00000148086
mitogen-activated protein kinase kinase 7
chr15_+_38397897 1.60 ENSDART00000142403
si:dkey-24p1.6
chr25_+_33787063 1.59

chr2_+_44659334 1.59 ENSDART00000155017
PAS domain containing serine/threonine kinase
chr19_-_6274458 1.57 ENSDART00000151405
Ets2 repressor factor
chr17_-_7661725 1.57 ENSDART00000143870
required for meiotic nuclear division 1 homolog
chr17_-_29253918 1.56 ENSDART00000104219
REST corepressor 1
chr18_+_38963423 1.55

chr2_+_35134340 1.55 ENSDART00000113609
ring finger and WD repeat domain 2
chr4_+_9466175 1.54 ENSDART00000012659
zgc:55888
chr3_-_42949526 1.53 ENSDART00000161127
axin 1
chr7_-_58856806 1.53 ENSDART00000159285
HAUS augmin-like complex, subunit 6
chr23_-_33811895 1.53 ENSDART00000131680
si:ch211-210c8.7
chr3_-_26060787 1.52 ENSDART00000113843
yippee-like 3
chr10_-_6587281 1.52 ENSDART00000163788
ENSDART00000171833
chromodomain helicase DNA binding protein 1
chr19_-_9584480 1.51 ENSDART00000091615
intermediate filament family orphan 1a
chr14_-_36096780 1.51 ENSDART00000173350
aspartylglucosaminidase
chr20_-_33584483 1.51 ENSDART00000177645
SMEK homolog 1, suppressor of mek1 (Dictyostelium)
chr24_-_12685892 1.51 ENSDART00000039312
importin 4
chr8_-_4270732 1.50 ENSDART00000134378
cut-like homeobox 2b
chr6_-_51811024 1.50 ENSDART00000031597
proteasome inhibitor subunit 1
chr13_+_18376540 1.50 ENSDART00000142622
si:ch211-198a12.6
chr8_+_39734109 1.49 ENSDART00000017153
Hermansky-Pudlak syndrome 4
chr9_-_12603178 1.49

chr8_+_17107665 1.49 ENSDART00000158707
ENSDART00000061758
mesoderm induction early response 1, family member 3 b
chr5_+_29052293 1.49 ENSDART00000035400
tuberous sclerosis 1a
chr6_-_52567422 1.49 ENSDART00000098421
ubiquinol-cytochrome c reductase complex assembly factor 1
chr2_+_1645259 1.48 ENSDART00000155956
synovial sarcoma, X breakpoint 2 interacting protein a
chr5_+_3683209 1.48 ENSDART00000132056
gametogenetin binding protein 2
chr10_+_29251234 1.47 ENSDART00000123033
phosphatidylinositol binding clathrin assembly protein a
chr2_+_30013537 1.47 ENSDART00000151848
RNA binding motif protein 33b
chr5_-_23013803 1.46 ENSDART00000137655
stromal antigen 2a
chr21_+_5854755 1.46 ENSDART00000149689
MOB kinase activator 1Bb
chr19_+_24483983 1.46 ENSDART00000141351
peroxisomal biogenesis factor 11 beta
chr3_+_40142679 1.44 ENSDART00000009411
BUD31 homolog (S. cerevisiae)
chr17_-_7661762 1.43 ENSDART00000135538
required for meiotic nuclear division 1 homolog
chr14_-_36096895 1.42 ENSDART00000173350
aspartylglucosaminidase
chr16_+_46443800 1.42 ENSDART00000131072
rapunzel 2
chr19_-_43359719 1.42 ENSDART00000086659
cysteine/histidine-rich 1
chr10_+_14530451 1.41 ENSDART00000026383
sigma non-opioid intracellular receptor 1
chr19_-_6274237 1.41 ENSDART00000151405
Ets2 repressor factor
chr10_-_33307992 1.41 ENSDART00000169064
B-cell CLL/lymphoma 7B, a
chr12_+_20290592 1.41 ENSDART00000115015
Rho GTPase activating protein 17a
chr6_-_31377513 1.40 ENSDART00000145715
adenylate kinase 4
chr21_+_15608741 1.40 ENSDART00000146909
coiled-coil-helix-coiled-coil-helix domain containing 10
chr5_-_14000166 1.39 ENSDART00000099566
si:ch211-244o22.2
chr4_+_1727494 1.39 ENSDART00000149448
ENSDARG00000095920
chr13_-_22831005 1.39 ENSDART00000143112
tetraspanin 15
chr17_+_15780112 1.38 ENSDART00000027667
ENSDART00000161637
ras-related GTP binding D
chr17_-_29254409 1.38 ENSDART00000104219
REST corepressor 1
chr3_-_56803756 1.37 ENSDART00000014103
zgc:112148
chr7_+_28824986 1.37 ENSDART00000052349
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr23_-_33753484 1.37 ENSDART00000138416
transcription factor CP2
chr3_-_42949479 1.35 ENSDART00000161127
axin 1
chr9_+_8919663 1.35 ENSDART00000134954
carbohydrate kinase domain containing
chr23_+_36608246 1.35 ENSDART00000113179
tetraspanin 31
chr15_+_35089305 1.34 ENSDART00000156515
zgc:55621
chr1_-_54488824 1.34 ENSDART00000150430
proliferation associated nuclear element
chr1_-_54505313 1.34 ENSDART00000100619
ENSDART00000163796
zgc:158803
chr17_+_37563386 1.34 ENSDART00000156281
metastasis associated 1
chr5_-_47419466 1.33 ENSDART00000078401
transmembrane protein 161B
chr18_+_20571460 1.33 ENSDART00000151990
WEE1 homolog 2 (S. pombe)
chr22_-_17663766 1.33 ENSDART00000147070
tight junction protein 3
chr5_-_47419401 1.33 ENSDART00000078401
transmembrane protein 161B
chr19_-_42933592 1.33 ENSDART00000007642
zgc:110239
chr12_-_28680442 1.33 ENSDART00000178777
oxysterol binding protein-like 7
chr18_-_44854242 1.32 ENSDART00000086823
signal recognition particle receptor (docking protein)

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 7.3 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
1.0 4.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
1.0 4.0 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
1.0 2.9 GO:0044375 regulation of peroxisome size(GO:0044375)
1.0 6.7 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479) negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.9 2.7 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.9 0.9 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.9 3.6 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.9 3.5 GO:0051150 regulation of smooth muscle cell differentiation(GO:0051150) negative regulation of smooth muscle cell differentiation(GO:0051151)
0.8 3.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119) mRNA pseudouridine synthesis(GO:1990481)
0.8 2.5 GO:0006449 regulation of translational termination(GO:0006449)
0.8 3.2 GO:0043243 positive regulation of protein complex disassembly(GO:0043243)
0.8 7.6 GO:0060281 regulation of oocyte development(GO:0060281)
0.7 2.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.7 2.2 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.7 2.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.6 3.9 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.6 3.2 GO:0060631 regulation of meiosis I(GO:0060631)
0.6 3.7 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.6 2.9 GO:0010922 positive regulation of phosphatase activity(GO:0010922) positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.6 5.7 GO:0046548 retinal rod cell development(GO:0046548)
0.6 1.7 GO:0071763 nuclear membrane organization(GO:0071763)
0.6 1.7 GO:0019376 galactosylceramide catabolic process(GO:0006683) galactolipid catabolic process(GO:0019376)
0.5 2.6 GO:1901993 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.5 1.5 GO:0002504 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.5 3.0 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.5 1.5 GO:1903232 melanosome assembly(GO:1903232)
0.5 2.9 GO:0050427 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.5 1.9 GO:0015882 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.5 6.3 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.5 2.7 GO:0040016 embryonic cleavage(GO:0040016)
0.4 3.5 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.4 1.7 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.4 0.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.4 4.2 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.4 1.5 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.4 1.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.4 1.1 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.4 2.8 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249) positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3 1.0 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.3 4.1 GO:0050796 regulation of insulin secretion(GO:0050796)
0.3 4.8 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.3 3.0 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.3 1.0 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.3 1.9 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.3 1.9 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.3 1.6 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.3 1.6 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.3 2.2 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.3 2.5 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.3 2.2 GO:0043536 positive regulation of blood vessel endothelial cell migration(GO:0043536) positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.3 0.9 GO:0070914 UV-damage excision repair(GO:0070914)
0.3 2.3 GO:1902743 regulation of lamellipodium assembly(GO:0010591) regulation of lamellipodium organization(GO:1902743)
0.3 0.9 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.3 1.7 GO:0032527 protein exit from endoplasmic reticulum(GO:0032527) endoplasmic reticulum to cytosol transport(GO:1903513)
0.3 3.7 GO:0006517 protein deglycosylation(GO:0006517)
0.3 1.7 GO:0021693 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698)
0.3 1.6 GO:0006043 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.3 2.9 GO:0006379 mRNA cleavage(GO:0006379)
0.2 1.5 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 1.0 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.2 6.3 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.2 1.5 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 1.2 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.2 0.7 GO:0090281 negative regulation of vascular permeability(GO:0043116) negative regulation of calcium ion import(GO:0090281)
0.2 1.4 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.2 1.2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.2 0.7 GO:0042126 nitrate metabolic process(GO:0042126) nitrate assimilation(GO:0042128)
0.2 0.5 GO:0071921 regulation of sister chromatid cohesion(GO:0007063) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.2 1.3 GO:0006309 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.2 0.7 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.2 1.3 GO:0030104 water homeostasis(GO:0030104)
0.2 2.2 GO:0001973 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.2 1.1 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.2 4.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.2 1.5 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.2 0.4 GO:0003179 heart valve morphogenesis(GO:0003179)
0.2 0.6 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.2 3.4 GO:0032482 Rab protein signal transduction(GO:0032482)
0.2 0.6 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.2 2.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.2 0.6 GO:0032570 response to progesterone(GO:0032570) medium-chain fatty acid biosynthetic process(GO:0051792)
0.2 2.6 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.2 0.8 GO:0046078 dUMP biosynthetic process(GO:0006226) dUMP metabolic process(GO:0046078)
0.2 0.6 GO:0006408 snRNA export from nucleus(GO:0006408) regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833)
0.2 2.7 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.2 1.5 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.2 0.4 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037)
0.2 2.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.2 0.6 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.2 0.9 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.2 0.7 GO:0006013 mannose metabolic process(GO:0006013)
0.2 2.0 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.2 0.7 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 1.6 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2 0.5 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.2 2.1 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.2 1.0 GO:0033198 response to ATP(GO:0033198)
0.2 0.7 GO:2001271 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 0.7 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.2 0.6 GO:0048103 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
0.2 1.1 GO:0006108 malate metabolic process(GO:0006108)
0.2 0.9 GO:0016578 histone deubiquitination(GO:0016578)
0.2 4.8 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.2 0.8 GO:0034367 macromolecular complex remodeling(GO:0034367)
0.1 4.0 GO:0048263 determination of dorsal identity(GO:0048263)
0.1 0.6 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.1 1.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.9 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.4 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.1 0.4 GO:0051645 Golgi localization(GO:0051645)
0.1 2.4 GO:0097192 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.1 1.3 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 1.2 GO:0097194 execution phase of apoptosis(GO:0097194)
0.1 0.7 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.1 0.9 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 3.3 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.1 1.8 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 1.6 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.1 0.4 GO:0002686 negative regulation of leukocyte migration(GO:0002686)
0.1 3.0 GO:2001236 regulation of extrinsic apoptotic signaling pathway(GO:2001236)
0.1 1.6 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 0.3 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 2.2 GO:0008354 germ cell migration(GO:0008354)
0.1 0.6 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.1 1.0 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.1 1.2 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.1 1.6 GO:0033866 coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.1 0.4 GO:0045190 B cell activation involved in immune response(GO:0002312) isotype switching(GO:0045190)
0.1 0.5 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.4 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.1 1.2 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.1 0.8 GO:0001845 phagolysosome assembly(GO:0001845)
0.1 0.3 GO:0003241 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 1.1 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.3 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.1 1.9 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 0.3 GO:0034085 establishment of sister chromatid cohesion(GO:0034085)
0.1 0.7 GO:0071169 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.1 1.5 GO:0051310 metaphase plate congression(GO:0051310)
0.1 1.3 GO:0008105 asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176)
0.1 0.9 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.4 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.1 0.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.5 GO:1901097 negative regulation of autophagosome maturation(GO:1901097) negative regulation of autophagosome assembly(GO:1902902)
0.1 0.9 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.1 1.1 GO:0043462 regulation of ATPase activity(GO:0043462)
0.1 1.2 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 0.4 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 0.4 GO:0000423 macromitophagy(GO:0000423)
0.1 2.0 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 0.8 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 0.3 GO:0051580 neurotransmitter uptake(GO:0001504) regulation of neurotransmitter uptake(GO:0051580) neurotransmitter reuptake(GO:0098810)
0.1 4.0 GO:0016575 histone deacetylation(GO:0016575)
0.1 0.2 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.1 0.2 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.1 1.3 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 1.5 GO:0001966 thigmotaxis(GO:0001966)
0.1 0.7 GO:0006611 protein export from nucleus(GO:0006611)
0.1 2.3 GO:0007062 sister chromatid cohesion(GO:0007062)
0.1 1.3 GO:0031100 organ regeneration(GO:0031100)
0.1 0.8 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 2.4 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.1 4.3 GO:0051225 spindle assembly(GO:0051225)
0.1 0.7 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.1 0.4 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.8 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 0.7 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.8 GO:0035794 positive regulation of mitochondrial membrane permeability(GO:0035794) mitochondrial outer membrane permeabilization(GO:0097345) positive regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902110) mitochondrial outer membrane permeabilization involved in programmed cell death(GO:1902686)
0.1 2.4 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.1 0.4 GO:0090316 positive regulation of intracellular protein transport(GO:0090316)
0.1 0.4 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.4 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.1 0.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 1.0 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.7 GO:0021767 mammillary body development(GO:0021767)
0.1 1.1 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 0.8 GO:2000380 regulation of mesoderm development(GO:2000380)
0.1 1.7 GO:0032465 regulation of cytokinesis(GO:0032465)
0.1 0.3 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.1 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.1 2.0 GO:0016579 protein deubiquitination(GO:0016579)
0.1 1.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.3 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1 0.1 GO:1903429 regulation of cell maturation(GO:1903429)
0.0 0.7 GO:0002250 adaptive immune response(GO:0002250)
0.0 0.1 GO:0055016 hypochord development(GO:0055016)
0.0 2.7 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 1.0 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 2.1 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 2.9 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.0 1.2 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 2.1 GO:0022406 membrane docking(GO:0022406) vesicle docking(GO:0048278)
0.0 0.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 4.0 GO:1990778 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0 0.7 GO:2000344 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.8 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 1.4 GO:0009306 protein secretion(GO:0009306)
0.0 2.9 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.8 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.7 GO:0003171 atrioventricular valve development(GO:0003171)
0.0 1.8 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 1.5 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.8 GO:0006829 zinc II ion transport(GO:0006829)
0.0 14.3 GO:0051603 proteolysis involved in cellular protein catabolic process(GO:0051603)
0.0 1.7 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 1.0 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.7 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 3.4 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.2 GO:0009084 glutamine family amino acid biosynthetic process(GO:0009084)
0.0 0.6 GO:0031297 replication fork processing(GO:0031297)
0.0 0.4 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:1901031 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 0.6 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.3 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
0.0 0.6 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.6 GO:0007164 establishment of planar polarity(GO:0001736) establishment of tissue polarity(GO:0007164)
0.0 0.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 2.1 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.4 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.5 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 2.0 GO:0017148 negative regulation of translation(GO:0017148) negative regulation of cellular amide metabolic process(GO:0034249)
0.0 0.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 5.8 GO:0016567 protein ubiquitination(GO:0016567)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0000077 DNA damage checkpoint(GO:0000077)
0.0 3.3 GO:0006869 lipid transport(GO:0006869)
0.0 1.2 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.4 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.7 GO:0060037 pharyngeal system development(GO:0060037)
0.0 1.4 GO:0001666 response to hypoxia(GO:0001666) response to decreased oxygen levels(GO:0036293)
0.0 0.2 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0070084 protein initiator methionine removal(GO:0070084)
0.0 0.8 GO:0007030 Golgi organization(GO:0007030)
0.0 0.1 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579) positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 0.2 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.7 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.3 GO:0072666 protein targeting to vacuole(GO:0006623) establishment of protein localization to vacuole(GO:0072666)
0.0 0.2 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.0 0.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.4 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.4 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.0 0.4 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 2.0 GO:0006486 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0035339 SPOTS complex(GO:0035339)
0.9 3.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.8 3.0 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.7 7.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.7 2.7 GO:0098536 deuterosome(GO:0098536)
0.5 3.6 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.5 5.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.5 1.5 GO:0031085 BLOC-3 complex(GO:0031085)
0.5 3.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.4 1.2 GO:0070390 transcription export complex 2(GO:0070390)
0.3 3.4 GO:0070652 HAUS complex(GO:0070652)
0.3 2.9 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.3 2.2 GO:0071546 pi-body(GO:0071546)
0.3 2.7 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.3 4.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.3 3.2 GO:0030667 secretory granule membrane(GO:0030667)
0.3 1.2 GO:0071141 SMAD protein complex(GO:0071141)
0.3 0.6 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.3 3.2 GO:0000815 ESCRT III complex(GO:0000815)
0.3 1.0 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.3 2.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.3 4.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.3 2.0 GO:0089701 U2AF(GO:0089701)
0.2 0.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.2 0.7 GO:1990745 EARP complex(GO:1990745)
0.2 1.6 GO:0070187 telosome(GO:0070187)
0.2 1.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.2 4.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 1.8 GO:0002102 podosome(GO:0002102)
0.2 1.0 GO:0035517 PR-DUB complex(GO:0035517)
0.2 0.6 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 1.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 2.5 GO:0034518 RNA cap binding complex(GO:0034518)
0.2 9.1 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.2 6.5 GO:0030496 midbody(GO:0030496)
0.2 0.7 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.2 1.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 9.3 GO:0005814 centriole(GO:0005814)
0.2 1.0 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 4.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.2 0.9 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 2.8 GO:0042555 MCM complex(GO:0042555)
0.1 2.0 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 1.0 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.1 0.7 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.3 GO:0034709 methylosome(GO:0034709)
0.1 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 3.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 7.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 1.3 GO:0008278 cohesin complex(GO:0008278)
0.1 0.3 GO:0071020 post-spliceosomal complex(GO:0071020)
0.1 1.0 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 3.6 GO:0000775 chromosome, centromeric region(GO:0000775)
0.1 0.7 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 1.4 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 0.2 GO:0030686 90S preribosome(GO:0030686)
0.1 0.4 GO:0008091 spectrin(GO:0008091)
0.1 0.6 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 4.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 5.8 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 16.6 GO:0005764 lysosome(GO:0005764)
0.1 1.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.3 GO:0043296 apical junction complex(GO:0043296)
0.1 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.5 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 0.9 GO:0061617 MICOS complex(GO:0061617)
0.1 2.2 GO:0005811 lipid particle(GO:0005811)
0.1 0.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.1 2.5 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 10.7 GO:0005730 nucleolus(GO:0005730)
0.0 1.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 1.6 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 4.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.5 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.6 GO:0035102 PRC1 complex(GO:0035102)
0.0 2.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.5 GO:0055037 recycling endosome(GO:0055037)
0.0 1.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.6 GO:0005930 axoneme(GO:0005930)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 1.7 GO:0005925 focal adhesion(GO:0005925)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.2 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.4 GO:0071565 nBAF complex(GO:0071565)
0.0 0.4 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.6 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.7 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.7 3.7 GO:0003948 N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity(GO:0003948)
0.7 2.0 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.6 6.5 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.6 3.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.6 1.7 GO:0004336 galactosylceramidase activity(GO:0004336)
0.5 1.6 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.5 2.2 GO:0034584 piRNA binding(GO:0034584)
0.5 1.6 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.5 3.1 GO:0070698 type I activin receptor binding(GO:0070698)
0.5 2.0 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.5 0.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.5 6.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.5 2.9 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.4 3.8 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.4 1.9 GO:0070551 endoribonuclease activity, cleaving siRNA-paired mRNA(GO:0070551)
0.4 1.9 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.4 1.1 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.4 1.1 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.3 1.0 GO:0070336 flap-structured DNA binding(GO:0070336)
0.3 1.3 GO:0004046 aminoacylase activity(GO:0004046)
0.3 2.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.3 1.9 GO:0015616 DNA translocase activity(GO:0015616)
0.3 2.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.3 2.4 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.3 1.5 GO:0042287 MHC protein binding(GO:0042287)
0.3 4.2 GO:0070411 I-SMAD binding(GO:0070411)
0.3 4.1 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.3 0.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.3 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.3 1.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.3 1.6 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.3 4.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.3 5.1 GO:0015248 sterol transporter activity(GO:0015248)
0.2 1.0 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2 1.9 GO:0034452 dynactin binding(GO:0034452)
0.2 1.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.2 0.7 GO:0008942 nitrite reductase [NAD(P)H] activity(GO:0008942) oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor(GO:0046857)
0.2 2.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 1.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2 2.0 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.2 0.7 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 0.9 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.2 0.7 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.2 0.6 GO:0008126 acetylesterase activity(GO:0008126)
0.2 3.6 GO:0004407 histone deacetylase activity(GO:0004407) NAD-dependent histone deacetylase activity(GO:0017136)
0.2 5.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.2 1.0 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 0.9 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.2 2.0 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.2 4.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.2 1.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 1.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 1.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.2 1.0 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.2 1.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.3 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.7 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.1 2.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 1.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 3.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.1 GO:0050699 WW domain binding(GO:0050699)
0.1 6.3 GO:0008013 beta-catenin binding(GO:0008013)
0.1 0.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.8 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.1 1.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.9 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 1.7 GO:0019894 kinesin binding(GO:0019894)
0.1 0.5 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 0.5 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 2.5 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 0.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 1.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.9 GO:0030619 U1 snRNA binding(GO:0030619)
0.1 0.3 GO:0004044 amidophosphoribosyltransferase activity(GO:0004044)
0.1 1.0 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 3.2 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 0.6 GO:0043531 ADP binding(GO:0043531)
0.1 0.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.5 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.5 GO:0070273 phosphatidylinositol-5-phosphate binding(GO:0010314) phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 1.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 2.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 0.8 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.9 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 1.0 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.2 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.9 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 1.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 1.2 GO:0008143 poly(A) binding(GO:0008143)
0.1 1.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.7 GO:0031267 small GTPase binding(GO:0031267)
0.1 11.1 GO:0042393 histone binding(GO:0042393)
0.1 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 11.0 GO:0042802 identical protein binding(GO:0042802)
0.1 1.3 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 1.7 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.1 2.9 GO:0003678 DNA helicase activity(GO:0003678)
0.1 2.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.3 GO:0001097 TFIIH-class transcription factor binding(GO:0001097) poly(C) RNA binding(GO:0017130)
0.0 1.9 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 15.5 GO:0003924 GTPase activity(GO:0003924)
0.0 1.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 3.7 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 2.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.3 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.7 GO:0032190 acrosin binding(GO:0032190)
0.0 1.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.5 GO:0002039 p53 binding(GO:0002039)
0.0 2.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.7 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.8 GO:0019239 deaminase activity(GO:0019239)
0.0 1.1 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.8 GO:0016866 intramolecular transferase activity(GO:0016866)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.7 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.7 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.6 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 3.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.5 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 7.5 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 1.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.0 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.0 0.3 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.7 GO:0045296 cadherin binding(GO:0045296)
0.0 0.3 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 2.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 2.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.0 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 3.5 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.3 4.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 6.5 PID AURORA B PATHWAY Aurora B signaling
0.2 1.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 1.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 6.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 2.8 PID AURORA A PATHWAY Aurora A signaling
0.1 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 3.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 1.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 2.3 PID ATM PATHWAY ATM pathway
0.1 1.4 PID RAS PATHWAY Regulation of Ras family activation
0.1 3.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.9 PID FOXO PATHWAY FoxO family signaling
0.1 3.7 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 1.3 PID BMP PATHWAY BMP receptor signaling
0.1 1.5 PID AP1 PATHWAY AP-1 transcription factor network
0.1 1.2 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 1.0 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 1.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.6 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.5 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.5 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.1 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.4 7.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 4.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 3.6 REACTOME KINESINS Genes involved in Kinesins
0.2 0.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 1.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 10.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.2 1.7 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 0.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 2.5 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1 0.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.0 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 5.4 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.0 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.9 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 1.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 1.7 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 2.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.9 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 0.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 2.1 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 1.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.6 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1 1.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 2.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.2 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.1 0.5 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 0.8 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.9 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.0 2.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.0 2.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME MEIOSIS Genes involved in Meiosis
0.0 0.3 REACTOME METABOLISM OF RNA Genes involved in Metabolism of RNA
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins