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Results for foxd5_foxd2

Z-value: 1.10

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Transcription factors associated with foxd5_foxd2

Gene Symbol Gene ID Gene Info
foxd5
ENSDARG00000042485 forkhead box D5
foxd2
ENSDARG00000058133 forkhead box D2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxd2dr10_dc_chr8_+_19642272_196422790.601.5e-02Click!
foxd5dr10_dc_chr8_+_30443651_304437620.302.7e-01Click!

Activity profile of foxd5_foxd2 motif

Sorted Z-values of foxd5_foxd2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of foxd5_foxd2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr22_-_17570306 3.90 ENSDART00000139361
gpx4a
glutathione peroxidase 4a
chr1_-_29669484 3.37 ENSDART00000164202
igf2bp2b
insulin-like growth factor 2 mRNA binding protein 2b
chr19_-_22802777 2.89 ENSDART00000151234
eppk1
epiplakin 1
chr4_+_12014166 2.64 ENSDART00000034401
ENSDART00000172691
cry1aa
cryptochrome circadian clock 1aa
chr18_-_46356213 2.52 ENSDART00000010813
foxa3
forkhead box A3
chr1_-_29669529 2.46 ENSDART00000164202
igf2bp2b
insulin-like growth factor 2 mRNA binding protein 2b
chr4_-_25226680 2.28 ENSDART00000066932
ENSDART00000066933
ENSDART00000157714
itih2
inter-alpha-trypsin inhibitor heavy chain 2
chr17_-_10682357 2.19 ENSDART00000064597
lgals3b
lectin, galactoside binding soluble 3b
chr20_+_4120302 2.09 ENSDART00000159837
cnksr3
cnksr family member 3
chr25_-_7635824 1.89 ENSDART00000126499
phf21ab
PHD finger protein 21Ab
chr5_-_21523520 1.74 ENSDART00000023306
asb12a
ankyrin repeat and SOCS box-containing 12a
chr12_-_6144233 1.74 ENSDART00000152292
a1cf
apobec1 complementation factor
chr3_+_36282205 1.73 ENSDART00000170318
si:ch1073-443f11.2
si:ch1073-443f11.2
chr8_+_15968469 1.69 ENSDART00000134787
elavl4
ELAV like neuron-specific RNA binding protein 4
chr13_+_32013916 1.68 ENSDART00000020270
osr1
odd-skipped related transciption factor 1
chr5_+_31606213 1.61 ENSDART00000126873
myhz2
myosin, heavy polypeptide 2, fast muscle specific
chr8_+_7937128 1.59 ENSDART00000137920
si:ch211-169p10.1
si:ch211-169p10.1
chr17_+_21944679 1.56 ENSDART00000063704
crip3
cysteine-rich protein 3
chr20_-_39003917 1.55

chr2_+_27000558 1.45 ENSDART00000099208
asph
aspartate beta-hydroxylase
chr25_+_386916 1.43

chr14_+_2969679 1.37 ENSDART00000044678
ENSDARG00000034011
ENSDARG00000034011
chr25_+_19051298 1.35 ENSDART00000067324
mfge8b
milk fat globule-EGF factor 8 protein b
chr6_-_55881470 1.30 ENSDART00000160991
cyp24a1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr25_+_24152717 1.29 ENSDART00000064646
tmem86a
transmembrane protein 86A
chr2_-_9950224 1.27 ENSDART00000146407
si:ch1073-170o4.1
si:ch1073-170o4.1
chr10_-_8336541 1.25 ENSDART00000163803
plpp1a
phospholipid phosphatase 1a
chr22_+_11726312 1.23 ENSDART00000155366
krt96
keratin 96
chr14_-_4014025 1.21 ENSDART00000157782
irf2
interferon regulatory factor 2
chr2_+_48052054 1.17 ENSDART00000159701
ftr23
finTRIM family, member 23
chr3_-_21149752 1.16 ENSDART00000003939
syngr1a
synaptogyrin 1a
chr20_-_39003972 1.15

chr7_-_12656353 1.10 ENSDART00000023301
ENSDART00000172901
ENSDART00000163045
ENSDART00000163461
sh3gl3a
SH3-domain GRB2-like 3a
chr8_+_48488009 1.07

chr6_-_8029184 1.01 ENSDART00000091628
ccdc151
coiled-coil domain containing 151
chr25_-_7635442 0.96 ENSDART00000021577
phf21ab
PHD finger protein 21Ab
chr6_-_32718634 0.93 ENSDART00000175666
mafaa
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa
chr19_-_31815128 0.93 ENSDART00000137292
tmem106bb
transmembrane protein 106Bb
chr2_+_43736542 0.91 ENSDART00000148454
itgb1b.1
integrin, beta 1b.1
chr8_+_7937320 0.91 ENSDART00000137920
si:ch211-169p10.1
si:ch211-169p10.1
chr9_+_4188263 0.90 ENSDART00000164543
kalrna
kalirin RhoGEF kinase a
chr6_+_40673803 0.87 ENSDART00000111639
rereb
arginine-glutamic acid dipeptide (RE) repeats b
chr14_-_24304373 0.87

chr11_+_41401893 0.86 ENSDART00000171655
AL929185.1
ENSDARG00000103982
chr24_+_9911748 0.86

chr5_+_36049885 0.84 ENSDART00000147667
alkbh6
alkB homolog 6
chr5_+_34798432 0.83 ENSDART00000098010
ptger4b
prostaglandin E receptor 4 (subtype EP4) b
chr16_+_11833310 0.82 ENSDART00000060266
ceacam1
carcinoembryonic antigen-related cell adhesion molecule 1
chr23_-_20332076 0.81 ENSDART00000147326
lamb2
laminin, beta 2 (laminin S)
chr8_-_16223730 0.81 ENSDART00000057590
dmrta2
DMRT-like family A2
chr17_-_9917832 0.80 ENSDART00000161574
ENSDART00000166081
zgc:109986
zgc:109986
chr22_-_11408859 0.77 ENSDART00000007649
mid1ip1b
MID1 interacting protein 1b
chr9_+_16437408 0.77 ENSDART00000006787
epha3
eph receptor A3
chr20_+_2937165 0.77 ENSDART00000135919
amd1
adenosylmethionine decarboxylase 1
chr16_-_30606364 0.75 ENSDART00000147986
lmna
lamin A
chr25_+_28717079 0.75 ENSDART00000162854
pkmb
pyruvate kinase, muscle, b
chr22_-_13018196 0.74 ENSDART00000028787
ahr1b
aryl hydrocarbon receptor 1b
chr23_+_24711233 0.73

chr21_-_44610563 0.73 ENSDART00000099528
spry4
sprouty homolog 4 (Drosophila)
chr25_-_33920256 0.71

chr1_-_36356039 0.70 ENSDART00000172111
ENSDART00000160056
nr3c2
nuclear receptor subfamily 3, group C, member 2
chr10_+_9764591 0.69 ENSDART00000091780
rc3h2
ring finger and CCCH-type domains 2
chr23_+_22763861 0.68

chr25_+_17327279 0.68 ENSDART00000061738
elmo3
engulfment and cell motility 3
chr23_-_17034625 0.67 ENSDART00000142546
cdc42l2
cell division cycle 42 like 2
chr5_+_66984082 0.67 ENSDART00000137700
si:dkey-70b23.2
si:dkey-70b23.2
chr18_+_9524331 0.66 ENSDART00000053125
sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr12_-_34786844 0.66 ENSDART00000027379
bicral
BRD4 interacting chromatin remodeling complex associated protein like
chr25_-_13580057 0.65 ENSDART00000090226
znf319b
zinc finger protein 319b
chr17_+_37985095 0.65 ENSDART00000075941
plekhh1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr6_+_4091384 0.65 ENSDART00000170351
nbeal1
neurobeachin-like 1
chr20_-_13728005 0.64 ENSDART00000152499
ezrb
ezrin b
chr9_-_37940101 0.63 ENSDART00000087663
sema5ba
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Ba
chr15_+_28435937 0.62 ENSDART00000142298
slc43a2a
solute carrier family 43 (amino acid system L transporter), member 2a
chr16_+_46526268 0.61 ENSDART00000134734
rpz5
rapunzel 5
chr2_-_37974443 0.60 ENSDART00000034595
cbln10
cerebellin 10
chr7_-_18295101 0.59 ENSDART00000173969
rgs12a
regulator of G protein signaling 12a
chr1_-_36356001 0.57 ENSDART00000172111
ENSDART00000160056
nr3c2
nuclear receptor subfamily 3, group C, member 2
chr25_-_7635175 0.55 ENSDART00000142439
phf21ab
PHD finger protein 21Ab
chr23_-_35392359 0.54 ENSDART00000166167
fam110c
family with sequence similarity 110, member C
chr18_+_9524184 0.54 ENSDART00000053125
sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr18_+_36683567 0.54 ENSDART00000098972
capn12
calpain 12
chr16_+_43235751 0.53 ENSDART00000065643
dbf4
DBF4 zinc finger
chr5_-_14990023 0.53

chr25_-_13057808 0.53 ENSDART00000172571
smpd3
sphingomyelin phosphodiesterase 3, neutral
chr10_+_4114961 0.52

chr6_-_40101104 0.52 ENSDART00000017402
ip6k2b
inositol hexakisphosphate kinase 2b
chr19_-_5416317 0.52 ENSDART00000010373
krt1-19d
keratin, type 1, gene 19d
chr7_+_28896401 0.52 ENSDART00000076345
slc38a8b
solute carrier family 38, member 8b
chr18_+_9524247 0.51 ENSDART00000053125
sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr8_+_13064944 0.51

KN150670v1_-_72156 0.50

chr12_-_5420963 0.50 ENSDART00000109305
tbc1d12b
TBC1 domain family, member 12b
chr24_-_24306469 0.49 ENSDART00000154149
BX323067.1
ENSDARG00000097984
chr8_+_15968636 0.48 ENSDART00000141173
elavl4
ELAV like neuron-specific RNA binding protein 4
chr18_+_19430116 0.48 ENSDART00000025107
map2k1
mitogen-activated protein kinase kinase 1
chr23_+_22763789 0.46

chr22_-_17570275 0.45 ENSDART00000099056
gpx4a
glutathione peroxidase 4a
chr3_-_49104540 0.45 ENSDART00000138503
btr02
bloodthirsty-related gene family, member 2
chr19_+_42492029 0.44 ENSDART00000150949
nfyc
nuclear transcription factor Y, gamma
chr22_+_24686610 0.43 ENSDART00000088027
ssx2ipb
synovial sarcoma, X breakpoint 2 interacting protein b
chr14_-_26078923 0.43 ENSDART00000022236
emx3
empty spiracles homeobox 3
chr24_+_9163779 0.43

chr3_-_21149711 0.43 ENSDART00000003939
syngr1a
synaptogyrin 1a
chr15_-_28329664 0.41 ENSDART00000175022
prpf8
pre-mRNA processing factor 8
chr16_+_22950567 0.40 ENSDART00000143957
flad1
flavin adenine dinucleotide synthetase 1
chr20_+_36330995 0.40 ENSDART00000131867
cnih3
cornichon family AMPA receptor auxiliary protein 3
chr22_+_2244267 0.40 ENSDART00000142890
si:dkey-4c15.9
si:dkey-4c15.9
chr11_+_30416953 0.39

chr5_-_11443522 0.39 ENSDART00000074979
rnft2
ring finger protein, transmembrane 2
chr1_+_32964583 0.37 ENSDART00000131664
nsun3
NOP2/Sun domain family, member 3
chr2_-_32404140 0.35 ENSDART00000148202
ubtfl
upstream binding transcription factor, like
chr10_+_39325810 0.35 ENSDART00000170079
foxred1
FAD-dependent oxidoreductase domain containing 1
chr9_+_3164027 0.35 ENSDART00000160567
ENSDART00000161216
dync1i2a
dynein, cytoplasmic 1, intermediate chain 2a
chr22_+_11726429 0.35 ENSDART00000155366
krt96
keratin 96
chr11_-_9479592 0.34 ENSDART00000175829
CU179643.1
ENSDARG00000086489
chr19_+_32679258 0.33

chr17_+_30431520 0.33 ENSDART00000153826
lpin1
lipin 1
chr19_+_32679320 0.33

chr2_+_57894141 0.33 ENSDART00000171264
ENSDART00000163278
si:ch211-155e24.3
si:ch211-155e24.3
chr11_+_6298048 0.32 ENSDART00000104409
ENSDART00000139882
ranbp3a
RAN binding protein 3a
chr14_+_34626233 0.32 ENSDART00000004550
rnf145a
ring finger protein 145a
chr25_-_10671899 0.31 ENSDART00000121724
lrp5
low density lipoprotein receptor-related protein 5
chr15_+_24756002 0.31 ENSDART00000110618
LRRC75A
leucine rich repeat containing 75A
chr15_+_24277664 0.30 ENSDART00000155502
sez6b
seizure related 6 homolog b
chr1_-_661529 0.30 ENSDART00000166786
ENSDART00000170483
appa
amyloid beta (A4) precursor protein a
chr6_+_28232386 0.29 ENSDART00000163057
FP101882.1
ENSDARG00000098121
chr20_-_26973962 0.29

chr25_+_5567388 0.28

chr16_-_7310925 0.27 ENSDART00000149030
nt5c3a
5'-nucleotidase, cytosolic IIIA
chr16_-_8711133 0.26

chr6_-_43030859 0.26 ENSDART00000161722
glyctk
glycerate kinase
chr21_+_27379622 0.25 ENSDART00000108763
cfb
complement factor B
chr20_-_51454057 0.24 ENSDART00000023064
slc35b2
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
chr3_-_34207879 0.24

chr6_-_10837245 0.24 ENSDART00000141017
sumo3a
small ubiquitin-like modifier 3a
chr23_-_28496509 0.24 ENSDART00000140448
c1ql4a
complement component 1, q subcomponent-like 4
chr18_+_5005303 0.23

chr5_+_29071526 0.23 ENSDART00000043096
ak8
adenylate kinase 8
chr22_-_16153692 0.23 ENSDART00000171331
vcam1b
vascular cell adhesion molecule 1b
chr15_+_28435875 0.22 ENSDART00000168453
slc43a2a
solute carrier family 43 (amino acid system L transporter), member 2a
chr19_+_5218864 0.22 ENSDART00000108541
si:dkey-89b17.4
si:dkey-89b17.4
chr6_+_4091251 0.22 ENSDART00000170351
nbeal1
neurobeachin-like 1
chr5_-_22847399 0.21 ENSDART00000169258
nlgn3b
neuroligin 3b
chr23_+_20779487 0.21 ENSDART00000079538
ccdc30
coiled-coil domain containing 30
chr5_-_13844114 0.21

chr9_-_6230087 0.21 ENSDART00000032368
tmtops2b
teleost multiple tissue opsin 2b
chr11_-_9479689 0.21 ENSDART00000175829
CU179643.1
ENSDARG00000086489
chr22_+_5633739 0.21 ENSDART00000106141
tma7
translation machinery associated 7 homolog
chr4_-_9866451 0.21 ENSDART00000133169
fbxo18
F-box protein, helicase, 18
chr16_-_1479139 0.20 ENSDART00000036348
sim1a
single-minded family bHLH transcription factor 1a
chr2_-_30710221 0.19 ENSDART00000090292
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr5_+_26195283 0.19 ENSDART00000053001
tcn2
transcobalamin II
chr16_-_43235448 0.19 ENSDART00000165293
slc25a40
solute carrier family 25, member 40
chr18_+_19430260 0.17 ENSDART00000025107
map2k1
mitogen-activated protein kinase kinase 1
chr14_+_20809902 0.17 ENSDART00000139103
aldob
aldolase b, fructose-bisphosphate
chr18_-_6844440 0.17 ENSDART00000142647
si:dkey-266m15.5
si:dkey-266m15.5
chr16_-_12282596 0.17 ENSDART00000110567
clstn3
calsyntenin 3
chr5_+_36049995 0.16 ENSDART00000111414
alkbh6
alkB homolog 6
chr22_-_11463487 0.16 ENSDART00000002691
tspan7b
tetraspanin 7b
chr6_+_24561921 0.14 ENSDART00000169283
znf644b
zinc finger protein 644b
chr9_+_30297924 0.14 ENSDART00000060174
jagn1a
jagunal homolog 1a
chr19_+_816354 0.14 ENSDART00000093304
nrm
nurim (nuclear envelope membrane protein
chr16_+_43236190 0.13 ENSDART00000065643
dbf4
DBF4 zinc finger
chr13_-_34926382 0.13 ENSDART00000178470
btbd3b
BTB (POZ) domain containing 3b
chr20_-_25537241 0.13 ENSDART00000153266
itsn2a
intersectin 2a
chr19_+_5219163 0.12

chr16_+_53391438 0.12 ENSDART00000010792
ptdss1a
phosphatidylserine synthase 1a
chr18_-_46355957 0.12 ENSDART00000010813
foxa3
forkhead box A3
chr8_+_26390972 0.12 ENSDART00000053447
ifrd2
interferon-related developmental regulator 2
chr25_-_7635613 0.12 ENSDART00000021577
phf21ab
PHD finger protein 21Ab
chr6_-_40700033 0.11 ENSDART00000113196
si:ch211-157b11.14
si:ch211-157b11.14
KN150442v1_-_37820 0.11 ENSDART00000158371
ptmab
prothymosin, alpha b
chr20_+_34814623 0.10 ENSDART00000034252
pnocb
prepronociceptin b
chr20_-_49307929 0.10 ENSDART00000057700
naa20
N(alpha)-acetyltransferase 20, NatB catalytic subunit
chr13_+_32609784 0.10 ENSDART00000160138
sobpa
sine oculis binding protein homolog (Drosophila) a
chr1_-_9256864 0.10 ENSDART00000041849
tmem8a
transmembrane protein 8A
chr16_+_18729942 0.10 ENSDART00000147844
ENSDART00000021596
rxrbb
retinoid x receptor, beta b
chr23_+_22763739 0.09

chr19_-_42668754 0.08 ENSDART00000132591
si:ch211-191i18.4
si:ch211-191i18.4
chr2_-_37151666 0.08 ENSDART00000146123
elavl1
ELAV like RNA binding protein 1
chr3_+_45345181 0.07

chr17_+_9918253 0.06 ENSDART00000169892
srp54
signal recognition particle 54
chr20_-_26973934 0.06

chr8_+_35483042 0.06 ENSDART00000111021
si:dkeyp-14d3.1
si:dkeyp-14d3.1
chr14_-_24304628 0.06

chr18_+_10957421 0.05 ENSDART00000166561
ttc38
tetratricopeptide repeat domain 38
chr20_+_16822321 0.05 ENSDART00000161226
psmc1b
proteasome 26S subunit, ATPase 1b
chr15_-_5911548 0.04

chr19_+_46631965 0.03 ENSDART00000158703
vps28
vacuolar protein sorting 28 (yeast)
chr18_+_22296882 0.03 ENSDART00000079139
ctcf
CCCTC-binding factor (zinc finger protein)
chr13_+_32609849 0.02 ENSDART00000160138
sobpa
sine oculis binding protein homolog (Drosophila) a
chr13_+_16390948 0.02 ENSDART00000122557
kcnma1a
potassium large conductance calcium-activated channel, subfamily M, alpha member 1a
chr4_-_9866515 0.02 ENSDART00000133169
fbxo18
F-box protein, helicase, 18
chr24_+_3447129 0.02 ENSDART00000134598
wdr37
WD repeat domain 37
chr6_-_10837765 0.01 ENSDART00000143730
sumo3a
small ubiquitin-like modifier 3a
chr8_-_52607867 0.01 ENSDART00000176559
ENSDARG00000099294
ENSDARG00000099294
chr21_+_37668334 0.00 ENSDART00000143621
nsd1b
nuclear receptor binding SET domain protein 1b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.7 2.6 GO:0048785 hatching gland development(GO:0048785)
0.5 1.4 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.5 2.9 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.5 1.9 GO:0035776 pronephric proximal tubule development(GO:0035776)
0.3 1.3 GO:0033280 response to vitamin D(GO:0033280) vitamin D metabolic process(GO:0042359)
0.3 1.3 GO:0071387 response to cortisol(GO:0051414) cellular response to cortisol stimulus(GO:0071387)
0.2 2.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.2 0.8 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.2 2.8 GO:0060324 face development(GO:0060324)
0.2 0.8 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.1 0.8 GO:0008216 spermidine metabolic process(GO:0008216)
0.1 1.7 GO:0016556 mRNA modification(GO:0016556)
0.1 0.7 GO:0090342 regulation of cell aging(GO:0090342)
0.1 0.6 GO:0050975 sensory perception of touch(GO:0050975)
0.1 0.3 GO:0035676 anterior lateral line neuromast hair cell development(GO:0035676)
0.1 0.4 GO:0046443 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.1 1.7 GO:0014823 response to activity(GO:0014823)
0.1 0.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571) regulation of nuclear cell cycle DNA replication(GO:0033262)
0.1 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.7 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.1 0.2 GO:0097105 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 0.8 GO:0070831 basement membrane assembly(GO:0070831)
0.1 0.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.9 GO:0032418 lysosome localization(GO:0032418)
0.1 0.7 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.1 0.5 GO:0030216 keratinocyte differentiation(GO:0030216)
0.1 0.4 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.9 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 4.4 GO:0006979 response to oxidative stress(GO:0006979)
0.0 0.8 GO:0015807 L-amino acid transport(GO:0015807)
0.0 0.8 GO:0021984 adenohypophysis development(GO:0021984)
0.0 1.4 GO:0007338 single fertilization(GO:0007338)
0.0 0.5 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0050832 defense response to fungus(GO:0050832)
0.0 1.7 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.5 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.5 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.6 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.2 GO:0051963 regulation of synapse assembly(GO:0051963) positive regulation of synapse assembly(GO:0051965)
0.0 0.3 GO:0006956 complement activation(GO:0006956)
0.0 0.6 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 0.7 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.4 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.3 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.8 GO:0046890 regulation of lipid biosynthetic process(GO:0046890)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 1.1 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 0.5 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.2 GO:0042476 odontogenesis(GO:0042476)
0.0 0.7 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 0.7 GO:0006909 phagocytosis(GO:0006909)
0.0 0.3 GO:0016925 protein sumoylation(GO:0016925)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0001772 immunological synapse(GO:0001772)
0.1 2.9 GO:0045095 keratin filament(GO:0045095)
0.1 1.6 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.4 GO:0031431 Dbf4-dependent protein kinase complex(GO:0031431)
0.1 2.2 GO:0043204 perikaryon(GO:0043204)
0.1 0.8 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 2.8 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 3.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.7 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 1.2 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 1.6 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.9 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.5 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.1 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.5 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.7 2.2 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.6 2.9 GO:0019215 intermediate filament binding(GO:0019215)
0.3 1.3 GO:0016803 ether hydrolase activity(GO:0016803)
0.3 0.9 GO:0098639 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3 0.8 GO:0004953 icosanoid receptor activity(GO:0004953)
0.2 0.7 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.4 GO:0030623 U5 snRNA binding(GO:0030623)
0.1 1.7 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.4 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.1 1.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.7 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.4 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 0.3 GO:0045503 dynein light chain binding(GO:0045503)
0.1 0.3 GO:0008887 glycerate kinase activity(GO:0008887)
0.1 1.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 0.2 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 5.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 0.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 2.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.5 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.4 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 3.3 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.8 GO:0005178 integrin binding(GO:0005178)
0.0 0.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.9 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 1.7 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.7 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 1.6 GO:0003774 motor activity(GO:0003774)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.0 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.0 0.0 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 2.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 2.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.2 1.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 1.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 0.5 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex