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Results for foxm1

Z-value: 0.91

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Transcription factors associated with foxm1

Gene Symbol Gene ID Gene Info
foxm1
ENSDARG00000003200 forkhead box M1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxm1dr10_dc_chr4_-_5822882_58230230.657.0e-03Click!

Activity profile of foxm1 motif

Sorted Z-values of foxm1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of foxm1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_+_30013086 4.26 ENSDART00000138050
rbm33b
RNA binding motif protein 33b
KN150623v1_+_258 2.20

chr18_-_11626694 2.08 ENSDART00000098565
CRACR2A
calcium release activated channel regulator 2A
chr17_-_45021393 2.04

chr13_+_24549364 1.97 ENSDART00000139854
zgc:66426
zgc:66426
chr18_+_17545564 1.73 ENSDART00000061007
mt2
metallothionein 2
chr14_+_25208174 1.67 ENSDART00000079016
thoc3
THO complex 3
chr22_+_818795 1.67 ENSDART00000003325
dennd2db
DENN/MADD domain containing 2Db
chr10_+_19059739 1.66 ENSDART00000038674
tmem230a
transmembrane protein 230a
chr1_-_50395003 1.58 ENSDART00000035150
spast
spastin
chr3_-_27470582 1.57 ENSDART00000077734
zgc:66160
zgc:66160
chr10_-_4641624 1.55 ENSDART00000163951
plppr1
phospholipid phosphatase related 1
chr15_-_29393378 1.54 ENSDART00000114492
si:dkey-52l18.4
si:dkey-52l18.4
chr1_+_51118765 1.49 ENSDART00000156349
BX548032.3
ENSDARG00000096092
chr4_+_16020464 1.30 ENSDART00000144611
CR749763.5
ENSDARG00000093983
chr25_-_7794186 1.30 ENSDART00000104686
ambra1b
autophagy/beclin-1 regulator 1b
chr25_-_24105014 1.28 ENSDART00000048507
uevld
UEV and lactate/malate dehyrogenase domains
chr12_-_25288550 1.27 ENSDART00000142674
zfp36l2
zinc finger protein 36, C3H type-like 2
chr3_-_54352535 1.23 ENSDART00000021977
ENSDART00000078973
dnmt1
DNA (cytosine-5-)-methyltransferase 1
chr7_-_2614300 1.21 ENSDART00000153548
BX323987.1
ENSDARG00000097745
chr3_+_1398333 1.19 ENSDART00000031823
triobpb
TRIO and F-actin binding protein b
chr13_+_12629211 1.17 ENSDART00000015127
zgc:100846
zgc:100846
chr17_-_7661725 1.17 ENSDART00000143870
rmnd1
required for meiotic nuclear division 1 homolog
chr17_+_52526741 1.17 ENSDART00000109891
angel1
angel homolog 1 (Drosophila)
chr20_+_48631807 1.16 ENSDART00000108884
prdm1c
PR domain containing 1c, with ZNF domain
chr15_+_29460803 1.08 ENSDART00000155198
gdpd5b
glycerophosphodiester phosphodiesterase domain containing 5b
chr6_+_40924559 1.07 ENSDART00000133599
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr1_+_45148002 1.06 ENSDART00000148086
map2k7
mitogen-activated protein kinase kinase 7
chr12_+_17032997 1.05 ENSDART00000028003
ankrd22
ankyrin repeat domain 22
chr6_-_6951460 1.05 ENSDART00000148879
nhej1
nonhomologous end-joining factor 1
chr22_+_1717236 1.04

chr1_+_52686770 1.03 ENSDART00000143909
tbc1d9
TBC1 domain family, member 9 (with GRAM domain)
chr4_-_4603294 1.02 ENSDART00000130601
CABZ01020840.1
ENSDARG00000090401
chr5_-_23092592 1.02 ENSDART00000024815
fam76b
family with sequence similarity 76, member B
chr8_-_22537326 1.01 ENSDART00000165640
porcnl
porcupine homolog like
chr6_+_40925259 1.01 ENSDART00000002728
ENSDART00000145153
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr13_-_22831005 0.99 ENSDART00000143112
tspan15
tetraspanin 15
chr25_-_28630138 0.98

chr1_+_52686620 0.97 ENSDART00000176087
tbc1d9
TBC1 domain family, member 9 (with GRAM domain)
chr16_-_28659489 0.97 ENSDART00000059053
rpp38
ribonuclease P/MRP 38 subunit
chr13_-_22831037 0.96 ENSDART00000057641
tspan15
tetraspanin 15
chr19_-_1571878 0.96

chr14_-_15777250 0.95 ENSDART00000165656
mxd3
MAX dimerization protein 3
chr2_+_30013537 0.94 ENSDART00000151848
rbm33b
RNA binding motif protein 33b
chr11_+_31346560 0.94 ENSDART00000124830
ENSDART00000162768
zgc:162816
zgc:162816
chr4_+_9010972 0.94 ENSDART00000058007
samm50l
sorting and assembly machinery component 50 homolog, like
chr3_-_22240424 0.92

chr22_-_22107535 0.91

chr4_+_14983045 0.90 ENSDART00000067046
cax1
cation/H+ exchanger protein 1
chr20_+_26005068 0.90 ENSDART00000016864
slc35f6
solute carrier family 35, member F6
chr23_-_33811895 0.87 ENSDART00000131680
si:ch211-210c8.7
si:ch211-210c8.7
chr17_-_11312263 0.86 ENSDART00000091159
adpgk2
ADP-dependent glucokinase 2
chr2_-_44924505 0.86 ENSDART00000113351
ncapd2
non-SMC condensin I complex, subunit D2
chr17_-_7661762 0.85 ENSDART00000135538
rmnd1
required for meiotic nuclear division 1 homolog
chr11_-_10001506 0.84 ENSDART00000123359
nlgn1
neuroligin 1
chr15_-_29393320 0.84 ENSDART00000114492
si:dkey-52l18.4
si:dkey-52l18.4
chr20_+_48631724 0.83 ENSDART00000108884
prdm1c
PR domain containing 1c, with ZNF domain
chr4_+_20901498 0.81

chr20_+_46837436 0.80 ENSDART00000145294
ENSDARG00000022260
ENSDARG00000022260
chr17_-_25612341 0.80 ENSDART00000126201
ENSDART00000105503
rab3gap2
RAB3 GTPase activating protein subunit 2 (non-catalytic)
chr2_+_37855019 0.78 ENSDART00000113337
parp2
poly (ADP-ribose) polymerase 2
chr24_+_5863770 0.78 ENSDART00000161104
mastl
microtubule associated serine/threonine kinase-like
chr7_-_3986977 0.78

chr9_-_21729953 0.76

chr5_-_9443859 0.74

chr9_+_21448920 0.73 ENSDART00000137024
ska3
spindle and kinetochore associated complex subunit 3
chr21_-_7322856 0.72 ENSDART00000151543
ENSDART00000114982
f2rl1.2
coagulation factor II (thrombin) receptor-like 1, tandem duplicate 2
KN149908v1_+_8072 0.71

chr25_-_7794262 0.70 ENSDART00000156761
ambra1b
autophagy/beclin-1 regulator 1b
chr4_-_30690750 0.70 ENSDART00000160757
CU302413.2
ENSDARG00000107562
chr17_-_23689380 0.69 ENSDART00000124661
papss2a
3'-phosphoadenosine 5'-phosphosulfate synthase 2a
chr13_+_33545847 0.69 ENSDART00000023379
mgme1
mitochondrial genome maintenance exonuclease 1
chr13_-_51617421 0.68 ENSDART00000121457
lbh
limb bud and heart development
chr8_+_23126036 0.68 ENSDART00000141175
gid8a
GID complex subunit 8 homolog a (S. cerevisiae)
chr22_+_24532479 0.67 ENSDART00000169847
wdr47b
WD repeat domain 47b
chr15_-_28654137 0.67 ENSDART00000156049
ssh2a
slingshot protein phosphatase 2a
chr23_+_37124543 0.66 ENSDART00000155706
CR762407.2
ENSDARG00000097111
chr17_+_12878081 0.66 ENSDART00000115208
fbxo33
F-box protein 33
chr21_-_23009910 0.66 ENSDART00000016167
zw10
zw10 kinetochore protein
chr10_-_244746 0.64 ENSDART00000136551
klhl35
kelch-like family member 35
chr16_+_40181425 0.64 ENSDART00000155421
cenpw
centromere protein W
chr11_-_36212977 0.64 ENSDART00000165203
usp48
ubiquitin specific peptidase 48
chr5_-_56874877 0.63

chr22_-_38947928 0.63 ENSDART00000008365
ncbp2
nuclear cap binding protein subunit 2
chr20_+_35156812 0.63

chr20_-_22899048 0.63 ENSDART00000063609
fip1l1a
FIP1 like 1a (S. cerevisiae)
chr13_-_33077267 0.63 ENSDART00000146138
trip11
thyroid hormone receptor interactor 11
chr17_-_25612397 0.63 ENSDART00000126201
ENSDART00000105503
rab3gap2
RAB3 GTPase activating protein subunit 2 (non-catalytic)
chr9_-_56423275 0.63

chr3_+_16772351 0.62 ENSDART00000164895
atp6v0a1a
ATPase, H+ transporting, lysosomal V0 subunit a1a
chr12_-_18997267 0.62 ENSDART00000149180
aco2
aconitase 2, mitochondrial
chr25_+_3521763 0.61 ENSDART00000160017
CABZ01058261.1
ENSDARG00000099194
chr6_+_60130210 0.61 ENSDART00000148557
aurka
aurora kinase A
chr6_+_27100350 0.61 ENSDART00000121558
atg4b
autophagy related 4B, cysteine peptidase
chr8_-_602656 0.60

chr13_+_24549249 0.60 ENSDART00000113981
zgc:66426
zgc:66426
chr19_-_38832985 0.60

chr4_-_36838449 0.59

chr13_-_17880164 0.58 ENSDART00000144813
march8
membrane-associated ring finger (C3HC4) 8
chr10_-_35108268 0.58 ENSDART00000147805
supt20
SPT20 homolog, SAGA complex component
chr8_-_24194821 0.58 ENSDART00000177464
CT025875.1
ENSDARG00000106046
chr1_+_52686829 0.58 ENSDART00000143909
tbc1d9
TBC1 domain family, member 9 (with GRAM domain)
chr23_+_39718769 0.58 ENSDART00000034690
otud3
OTU deubiquitinase 3
chr15_-_37687982 0.57 ENSDART00000154641
proser3
proline and serine rich 3
chr12_+_30119447 0.57 ENSDART00000102081
afap1l2
actin filament associated protein 1-like 2
chr16_+_51328478 0.57 ENSDART00000168162
FQ323156.1
ENSDARG00000100697
chr7_+_55648832 0.57 ENSDART00000082780
ACSF3
acyl-CoA synthetase family member 3
chr7_+_23752492 0.56 ENSDART00000141165
tinf2
TERF1 (TRF1)-interacting nuclear factor 2
chr3_+_1398365 0.56 ENSDART00000031823
triobpb
TRIO and F-actin binding protein b
chr19_+_25569817 0.56 ENSDART00000163220
si:ch211-239d6.2
si:ch211-239d6.2
chr16_+_8067699 0.55 ENSDART00000126041
ano10a
anoctamin 10a
chr2_+_33943680 0.54 ENSDART00000109849
kif2c
kinesin family member 2C
chr25_-_25339397 0.53 ENSDART00000171589
hrasa
v-Ha-ras Harvey rat sarcoma viral oncogene homolog a
chr22_-_38947987 0.53 ENSDART00000008365
ncbp2
nuclear cap binding protein subunit 2
chr20_+_48631844 0.51 ENSDART00000108884
prdm1c
PR domain containing 1c, with ZNF domain
chr10_+_22921629 0.51 ENSDART00000057291
arrb2a
arrestin, beta 2a
chr7_-_5172270 0.51 ENSDART00000172963
FP236789.1
ENSDARG00000105406
chr4_-_20119812 0.51 ENSDART00000100867
fam3c
family with sequence similarity 3, member C
chr22_-_9905160 0.50 ENSDART00000136404
si:dkey-253d23.11
si:dkey-253d23.11
chr8_-_18176067 0.50 ENSDART00000114177
si:ch211-241d21.5
si:ch211-241d21.5
chr2_-_37821146 0.49 ENSDART00000154124
nfatc4
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chr2_+_43355846 0.48 ENSDART00000056402
pard3ab
par-3 family cell polarity regulator alpha, b
chr14_+_44343015 0.48 ENSDART00000079866
slc30a9
solute carrier family 30 (zinc transporter), member 9
chr1_-_54488896 0.47 ENSDART00000150430
pane1
proliferation associated nuclear element
chr1_+_16834347 0.46 ENSDART00000005593
ENSDART00000140076
casp3a
caspase 3, apoptosis-related cysteine peptidase a
chr7_+_28844711 0.46 ENSDART00000052345
tradd
tnfrsf1a-associated via death domain
chr1_-_28057759 0.45 ENSDART00000152589
timmdc1
translocase of inner mitochondrial membrane domain containing 1
chr24_-_2386805 0.44

chr14_+_8332180 0.43 ENSDART00000123506
si:dkeyp-115e12.6
si:dkeyp-115e12.6
chr11_+_30006715 0.43 ENSDART00000157272
ENSDART00000003475
ppef1
protein phosphatase, EF-hand calcium binding domain 1
chr7_-_38540389 0.42

chr8_+_28377022 0.42 ENSDART00000158788
klhl12
kelch-like family member 12
chr4_-_2370333 0.42 ENSDART00000131046
si:ch73-278m9.1
si:ch73-278m9.1
chr25_-_13990944 0.41 ENSDART00000124140
zgc:101566
zgc:101566
chr24_+_5863597 0.41 ENSDART00000161104
mastl
microtubule associated serine/threonine kinase-like
chr8_+_23125906 0.41 ENSDART00000131617
gid8a
GID complex subunit 8 homolog a (S. cerevisiae)
chr20_+_46837276 0.41 ENSDART00000145294
ENSDARG00000022260
ENSDARG00000022260
chr13_-_51617449 0.41 ENSDART00000121457
lbh
limb bud and heart development
chr4_+_5332964 0.39 ENSDART00000123375
zgc:113263
zgc:113263
chr8_-_51537679 0.39 ENSDART00000147742
fgfr1a
fibroblast growth factor receptor 1a
chr8_+_23126151 0.39 ENSDART00000146264
gid8a
GID complex subunit 8 homolog a (S. cerevisiae)
chr2_-_47827343 0.38 ENSDART00000056882
cul3a
cullin 3a
chr18_+_18450245 0.38 ENSDART00000043843
siah1
siah E3 ubiquitin protein ligase 1
chr17_-_15021379 0.38 ENSDART00000012877
ENSDART00000109190
ero1a
endoplasmic reticulum oxidoreductase alpha
chr18_-_20605032 0.38 ENSDART00000134722
bcl2l13
BCL2-like 13 (apoptosis facilitator)
chr21_-_2211701 0.38 ENSDART00000175686
si:dkey-50i6.6
si:dkey-50i6.6
chr5_+_32215942 0.38 ENSDART00000047377
crata
carnitine O-acetyltransferase a
chr8_+_40176716 0.37 ENSDART00000055861
rnf34a
ring finger protein 34a
chr8_+_2398268 0.37 ENSDART00000133938
ENSDART00000002764
polb
polymerase (DNA directed), beta
chr15_+_31709330 0.37 ENSDART00000159634
b3glcta
beta 3-glucosyltransferase a
chr10_+_573116 0.37 ENSDART00000129856
ENSDART00000110384
smad4a
SMAD family member 4a
chr7_+_60054043 0.36 ENSDART00000145201
ppp1r14bb
protein phosphatase 1, regulatory (inhibitor) subunit 14Bb
chr15_-_14653696 0.36 ENSDART00000172195
adck4
aarF domain containing kinase 4
chr8_+_50543161 0.36 ENSDART00000176614
ENSDART00000174435
PEBP4
phosphatidylethanolamine binding protein 4
chr15_+_23598869 0.36 ENSDART00000152320
si:dkey-182i3.10
si:dkey-182i3.10
chr15_-_23849212 0.36 ENSDART00000059354
rad1
RAD1 homolog (S. pombe)
chr11_-_17882817 0.35 ENSDART00000155443
qrich1
glutamine-rich 1
chr7_-_7533548 0.35 ENSDART00000173376
intu
inturned planar cell polarity protein
chr8_+_44448437 0.35 ENSDART00000143807
mhc1laa
major histocompatibility complex class I LAA
chr5_-_51256304 0.35 ENSDART00000125535
mtx3
metaxin 3
chr6_+_27100249 0.35 ENSDART00000121558
atg4b
autophagy related 4B, cysteine peptidase
chr7_-_13661739 0.33 ENSDART00000062257
slc39a1
solute carrier family 39 (zinc transporter), member 1
chr25_-_20633069 0.33 ENSDART00000172170
si:ch211-127m7.2
si:ch211-127m7.2
chr4_-_2814833 0.33

chr5_+_22470177 0.33 ENSDART00000020434
brwd3
bromodomain and WD repeat domain containing 3
chr22_+_38948272 0.32 ENSDART00000085685
sirt7
sirtuin 7
chr19_+_19917767 0.32

chr1_-_22577855 0.32 ENSDART00000175685
rfc1
replication factor C (activator 1) 1
chr19_-_12058542 0.32 ENSDART00000168308
si:ch73-49k18.1
si:ch73-49k18.1
chr20_+_38955797 0.32

chr6_-_13910679 0.31 ENSDART00000065361
etv5b
ets variant 5b
chr14_+_15982295 0.31 ENSDART00000106593
prpf19
pre-mRNA processing factor 19
chr15_+_1688846 0.30 ENSDART00000021299
nmd3
NMD3 ribosome export adaptor
chr17_+_8642373 0.30 ENSDART00000105326
tonsl
tonsoku-like, DNA repair protein
chr7_-_6209659 0.28 ENSDART00000173032
CU457819.4
Histone H3.2
chr10_+_15496705 0.28 ENSDART00000129441
erbb2ip
erbb2 interacting protein
chr2_+_11422195 0.28 ENSDART00000019078
lhx8a
LIM homeobox 8a
chr16_-_53978295 0.27 ENSDART00000158047
ZNRF2
zinc and ring finger 2
chr11_-_44738541 0.27 ENSDART00000168066
afmid
arylformamidase
chr13_+_12629243 0.27 ENSDART00000015127
zgc:100846
zgc:100846
chr9_+_42744931 0.27

chr9_+_21729882 0.26 ENSDART00000132211
arhgef7a
Rho guanine nucleotide exchange factor (GEF) 7a
chr19_+_19164500 0.26 ENSDART00000165728
vps52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr10_+_19059663 0.26 ENSDART00000038674
tmem230a
transmembrane protein 230a
chr11_-_17883113 0.26 ENSDART00000040171
qrich1
glutamine-rich 1
chr7_+_38540519 0.26 ENSDART00000052322
zgc:110699
zgc:110699
chr25_+_35540123 0.25 ENSDART00000126326
rpgrip1l
RPGRIP1-like
chr10_-_4641512 0.25 ENSDART00000163951
plppr1
phospholipid phosphatase related 1
chr15_+_31709362 0.25 ENSDART00000159634
b3glcta
beta 3-glucosyltransferase a
chr22_+_1540035 0.24 ENSDART00000159050
si:ch211-255f4.8
si:ch211-255f4.8
chr9_-_55250643 0.24 ENSDART00000085693
gpm6bb
glycoprotein M6Bb
chr18_+_15964146 0.24

chr14_-_44329331 0.23 ENSDART00000098640
grhpra
glyoxylate reductase/hydroxypyruvate reductase a
chr14_-_51764932 0.23 ENSDART00000158353
exosc3
exosome component 3
chr11_-_42148337 0.23 ENSDART00000160704
slmapa
sarcolemma associated protein a
chr1_+_39849028 0.23 ENSDART00000135578
scoca
short coiled-coil protein a
chr7_+_38540586 0.23 ENSDART00000052322
zgc:110699
zgc:110699
chr14_-_41020814 0.23 ENSDART00000169247
cstf2
cleavage stimulation factor, 3' pre-RNA, subunit 2
chr23_-_5188577 0.22 ENSDART00000123191
ube2t
ubiquitin-conjugating enzyme E2T (putative)
chr22_+_1717284 0.22

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0043243 positive regulation of protein complex disassembly(GO:0043243)
0.4 1.2 GO:0006408 snRNA export from nucleus(GO:0006408) regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833)
0.3 2.0 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.3 0.8 GO:0097105 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.3 1.0 GO:0061355 Wnt protein secretion(GO:0061355)
0.2 0.7 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.2 1.7 GO:0090050 positive regulation of blood vessel endothelial cell migration(GO:0043536) positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2 1.4 GO:0036268 swimming(GO:0036268)
0.2 0.7 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.2 1.2 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.2 0.9 GO:0019478 D-amino acid catabolic process(GO:0019478) D-serine catabolic process(GO:0036088) D-amino acid metabolic process(GO:0046416) D-serine metabolic process(GO:0070178)
0.2 0.7 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.2 1.1 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.2 0.9 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 0.6 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.2 0.5 GO:0043393 G-protein coupled receptor internalization(GO:0002031) regulation of protein binding(GO:0043393)
0.2 0.8 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.2 0.5 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 1.4 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.5 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 0.6 GO:0000212 meiotic spindle organization(GO:0000212)
0.1 1.0 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.2 GO:0051589 negative regulation of neurotransmitter transport(GO:0051589)
0.1 0.7 GO:0034035 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.6 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.9 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.4 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.4 GO:2001271 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.9 GO:0032387 negative regulation of intracellular transport(GO:0032387)
0.1 1.5 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.1 0.5 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 1.8 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.1 0.6 GO:0001845 phagolysosome assembly(GO:0001845)
0.1 0.2 GO:1900274 positive regulation of phospholipase C activity(GO:0010863) skin morphogenesis(GO:0043589) regulation of phospholipase C activity(GO:1900274)
0.1 0.3 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.1 0.6 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.4 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 1.7 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1 0.4 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 0.2 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.1 1.5 GO:0048263 determination of dorsal identity(GO:0048263)
0.1 0.7 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 0.2 GO:0010660 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.0 0.8 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.6 GO:0031297 replication fork processing(GO:0031297)
0.0 0.8 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.3 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.3 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.4 GO:0051310 metaphase plate congression(GO:0051310)
0.0 1.8 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.2 GO:0032534 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.0 0.3 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 2.0 GO:0014904 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 0.2 GO:0090178 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 2.6 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.5 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.3 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.4 GO:0050906 detection of stimulus involved in sensory perception(GO:0050906)
0.0 0.3 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.3 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.6 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 2.1 GO:0006413 translational initiation(GO:0006413)
0.0 2.0 GO:1990778 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0 0.4 GO:0060173 limb development(GO:0060173)
0.0 0.7 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 1.1 GO:0003401 axis elongation(GO:0003401)
0.0 0.9 GO:0006096 glycolytic process(GO:0006096)
0.0 0.4 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.1 GO:0033314 mitotic G2 DNA damage checkpoint(GO:0007095) mitotic DNA replication checkpoint(GO:0033314)
0.0 0.4 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.7 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 2.6 GO:0051493 regulation of cytoskeleton organization(GO:0051493)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0032807 DNA ligase IV complex(GO:0032807)
0.2 1.7 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 1.1 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.2 1.1 GO:0070187 telosome(GO:0070187)
0.2 1.0 GO:0001650 fibrillar center(GO:0001650)
0.1 0.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.6 GO:0035101 FACT complex(GO:0035101)
0.1 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 1.2 GO:0034518 RNA cap binding complex(GO:0034518)
0.1 0.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 1.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.4 GO:0000803 sex chromosome(GO:0000803) inactive sex chromosome(GO:0098577)
0.0 0.6 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.0 1.5 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.0 1.6 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 1.6 GO:0030496 midbody(GO:0030496)
0.0 0.2 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 1.4 GO:0005776 autophagosome(GO:0005776)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 1.3 GO:0005930 axoneme(GO:0005930)
0.0 0.4 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.1 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.6 GO:0060076 excitatory synapse(GO:0060076)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.3 1.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.3 0.9 GO:0016841 ammonia-lyase activity(GO:0016841)
0.2 1.0 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.2 0.7 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 0.6 GO:0035174 histone serine kinase activity(GO:0035174)
0.2 0.8 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.4 GO:0008465 glycerate dehydrogenase activity(GO:0008465)
0.1 0.4 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.1 0.6 GO:0042287 MHC protein binding(GO:0042287)
0.1 0.7 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.8 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.7 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.1 1.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 1.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.3 GO:0004061 arylformamidase activity(GO:0004061)
0.1 0.9 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.1 0.6 GO:0051117 ATPase binding(GO:0051117)
0.1 0.4 GO:0017130 TFIIH-class transcription factor binding(GO:0001097) poly(C) RNA binding(GO:0017130)
0.1 1.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 1.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.6 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.5 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.4 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 1.2 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 2.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887) DNA polymerase activity(GO:0034061)
0.0 0.3 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.4 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.8 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.4 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.1 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 2.7 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 2.3 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.0 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 2.1 PID AURORA B PATHWAY Aurora B signaling
0.0 1.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.2 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.5 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.8 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase