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Results for foxn1

Z-value: 1.11

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Transcription factors associated with foxn1

Gene Symbol Gene ID Gene Info
ENSDARG00000011879 forkhead box N1

Activity profile of foxn1 motif

Sorted Z-values of foxn1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of foxn1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr23_+_19663746 3.48 ENSDART00000170149
sarcolemma associated protein b
chr9_-_46614949 3.35 ENSDART00000009790
connexin 43.4
chr17_-_45021393 2.93

chr9_+_21982644 2.43 ENSDART00000134915
REV1, polymerase (DNA directed)
chr13_+_22973764 2.29 ENSDART00000110266
phosphoinositide-3-kinase adaptor protein 1
chr12_-_25058837 2.11 ENSDART00000135368
ras homolog family member Q
KN150633v1_+_13413 2.04

chr22_-_38473263 1.99 ENSDART00000098461
protein tyrosine kinase 7a
chr25_+_34340569 1.99 ENSDART00000157638
transmembrane protein 231
chr19_-_6274169 1.97 ENSDART00000140347
ENSDART00000092656
Ets2 repressor factor
chr9_+_21982679 1.95 ENSDART00000134915
REV1, polymerase (DNA directed)
chr4_+_71390178 1.84 ENSDART00000174128
zgc:152938
chr8_+_5222023 1.80 ENSDART00000035676
BCL2/adenovirus E1B interacting protein 3-like a
chr6_+_40994859 1.78 ENSDART00000151419
transforming growth factor, alpha
chr20_-_47576872 1.76 ENSDART00000067776
RAB10, member RAS oncogene family
chr13_-_50940551 1.73

chr14_+_22159893 1.69 ENSDART00000019296
growth differentiation factor 9
chr6_+_40994918 1.67 ENSDART00000151419
transforming growth factor, alpha
chr23_+_6652454 1.67 ENSDART00000081763
RNA binding motif protein 38
chr5_-_53907908 1.66 ENSDART00000158069
Sjogren syndrome nuclear autoantigen 1
chr20_-_14885629 1.60 ENSDART00000160481
SUN domain containing ossification factor
chr10_+_22065599 1.57 ENSDART00000143461
nucleophosmin 1a (nucleolar phosphoprotein B23, numatrin)
chr25_-_36512943 1.56 ENSDART00000114508
hypoxanthine phosphoribosyltransferase 1, like
chr4_-_12103129 1.53 ENSDART00000048391
ENSDART00000132650
B-Raf proto-oncogene, serine/threonine kinase
chr5_+_29193876 1.53 ENSDART00000045410
Thy-1 cell surface antigen
chr20_-_14885599 1.53 ENSDART00000160481
SUN domain containing ossification factor
chr3_+_59972297 1.52

chr19_-_6274458 1.49 ENSDART00000151405
Ets2 repressor factor
chr6_+_40995061 1.47 ENSDART00000151419
transforming growth factor, alpha
chr13_-_50940520 1.46

chr21_-_14154489 1.45 ENSDART00000114715
mannosidase, alpha, class 1B, member 1a
chr5_+_22541236 1.44 ENSDART00000171719
alpha thalassemia/mental retardation syndrome X-linked, like
chr22_+_26840517 1.42 ENSDART00000158756
CREB binding protein a
chr23_+_30971404 1.40 ENSDART00000146859
Cdk5 and Abl enzyme substrate 2a
chr10_+_29251234 1.40 ENSDART00000123033
phosphatidylinositol binding clathrin assembly protein a
chr9_+_21982756 1.35 ENSDART00000059652
REV1, polymerase (DNA directed)
chr22_+_26270259 1.33 ENSDART00000060898
mitochondrial ribosomal protein S28
chr5_-_29782745 1.33 ENSDART00000125381
grass carp reovirus (GCRV)-induced gene 2o
chr8_-_602656 1.31

chr10_-_1185831 1.30 ENSDART00000114261
bone morphogenetic protein receptor, type IBb
chr21_+_21242470 1.30 ENSDART00000148346
inositol-trisphosphate 3-kinase Ca
chr9_-_8916789 1.30 ENSDART00000144673
RAB20, member RAS oncogene family
chr22_-_38473305 1.29 ENSDART00000098461
protein tyrosine kinase 7a
chr3_-_15325357 1.28 ENSDART00000139575
spinster homolog 1 (Drosophila)
chr15_+_35105420 1.28 ENSDART00000153840
si:ch73-95l15.5
chr22_+_62610 1.26 ENSDART00000062264
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr13_+_35799681 1.24 ENSDART00000046115
major facilitator superfamily domain containing 2aa
chr13_+_35799602 1.24 ENSDART00000046115
major facilitator superfamily domain containing 2aa
chr5_-_18458903 1.24 ENSDART00000145210
ankyrin repeat and LEM domain containing 2
chr3_+_58417512 1.23 ENSDART00000154122
si:ch211-165g14.1
chr3_+_1054368 1.22 ENSDART00000153693
si:ch73-166o21.1
chr2_+_23004159 1.21 ENSDART00000123442
zgc:161973
chr3_+_18691103 1.20 ENSDART00000128626
transmembrane protein 104
chr2_-_32403565 1.20 ENSDART00000056634
upstream binding transcription factor, like
chr1_+_40428827 1.19 ENSDART00000145272
low density lipoprotein receptor-related protein associated protein 1
chr3_-_18655432 1.18 ENSDART00000034489
methionine sulfoxide reductase B1a
chr16_+_26673760 1.17 ENSDART00000141393
protein tyrosine phosphatase, non-receptor type 3
chr19_-_6274237 1.14 ENSDART00000151405
Ets2 repressor factor
chr16_+_53632289 1.14 ENSDART00000124691
sphingomyelin phosphodiesterase 5
chr20_-_50211708 1.13 ENSDART00000148892
exostosin-like glycosyltransferase 3
chr13_-_32324315 1.10

chr7_+_66660882 1.08 ENSDART00000082664
SET binding factor 2
chr13_+_28785104 1.07

chr3_+_7877162 1.07 ENSDART00000057434
ENSDART00000170291
hook microtubule-tethering protein 2
chr9_-_46615212 1.07 ENSDART00000009790
connexin 43.4
chr9_-_41288163 1.05 ENSDART00000131681
asparagine synthetase domain containing 1
chr5_-_34600655 1.05 ENSDART00000164396
FCH domain only 2
chr10_+_37556367 1.04 ENSDART00000135642
musashi RNA-binding protein 2a
chr9_-_46615155 1.03 ENSDART00000009790
connexin 43.4
chr17_+_34238753 1.02 ENSDART00000014306
membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5)
chr19_+_29716509 1.02 ENSDART00000142694
ENSDART00000009149
transmembrane protein 57a
chr4_+_71390236 1.00 ENSDART00000174116
zgc:152938
chr13_+_32323781 1.00 ENSDART00000057421
retinol dehydrogenase 14a (all-trans/9-cis/11-cis)
chr3_-_29760674 0.99 ENSDART00000014021
solute carrier family 25, member 39
chr16_-_40508858 0.99 ENSDART00000032389
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr9_-_8916860 0.98 ENSDART00000138527
RAB20, member RAS oncogene family
chr10_+_29247498 0.98

chr21_-_36710989 0.98 ENSDART00000086060
mitochondrial ribosomal protein L22
chr9_-_8917143 0.98 ENSDART00000138527
RAB20, member RAS oncogene family
chr7_+_69290790 0.98 ENSDART00000109507
Rap1 GTPase-GDP dissociation stimulator 1
chr10_+_16543480 0.97 ENSDART00000121864
solute carrier family 27 (fatty acid transporter), member 6
chr5_+_62595346 0.97 ENSDART00000140065
si:ch73-37h15.2
chr10_+_384571 0.96 ENSDART00000129757
si:ch211-242f23.8
chr22_-_38472936 0.95 ENSDART00000098461
protein tyrosine kinase 7a
chr3_-_29760552 0.94 ENSDART00000014021
solute carrier family 25, member 39
chr19_+_29716557 0.94 ENSDART00000142694
ENSDART00000009149
transmembrane protein 57a
chr16_+_23367580 0.93 ENSDART00000015956
ephrin-A1b
KN149779v1_-_14268 0.93 ENSDART00000162865
intraflagellar transport 27 homolog (Chlamydomonas)
chr23_+_35551931 0.92 ENSDART00000132609
cyclin T1
chr2_-_48401770 0.91 ENSDART00000056277
GRB10 interacting GYF protein 2
chr19_+_770644 0.91 ENSDART00000150926
glutathione S-transferase rho
chr8_+_5222145 0.91 ENSDART00000035676
BCL2/adenovirus E1B interacting protein 3-like a
chr25_-_34340016 0.90 ENSDART00000039485
GABA(A) receptor-associated protein like 2
chr6_-_7529384 0.90 ENSDART00000091836
ENSDART00000151697
ubinuclein 2a
chr20_+_23707789 0.90

chr23_+_30971437 0.90 ENSDART00000146859
Cdk5 and Abl enzyme substrate 2a
chr4_+_71390285 0.89 ENSDART00000174116
zgc:152938
chr17_-_52933930 0.88

chr2_-_6380292 0.88 ENSDART00000092182
protein phosphatase, Mg2+/Mn2+ dependent, 1La
chr17_-_23874858 0.87 ENSDART00000122108
PDZ domain containing 8
chr15_-_23973374 0.87 ENSDART00000088808
ubiquitin specific peptidase 32
chr6_+_40994992 0.84 ENSDART00000151419
transforming growth factor, alpha
chr10_+_29251158 0.83 ENSDART00000123033
phosphatidylinositol binding clathrin assembly protein a
chr18_+_18890626 0.83 ENSDART00000019581
ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)
chr7_+_8834138 0.82 ENSDART00000173250
proprotein convertase subtilisin/kexin type 6
chr20_-_6153384 0.82 ENSDART00000161566
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr11_-_22210506 0.81 ENSDART00000146873
transmembrane protein 183A
chr16_+_51597530 0.81

chr8_+_13753663 0.80

chr15_-_35020312 0.80 ENSDART00000154094
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase a
chr5_+_1461715 0.80 ENSDART00000054057
DDRGK domain containing 1
chr20_+_23707625 0.79

chr6_+_12269410 0.79 ENSDART00000149529
serine/threonine kinase 24b (STE20 homolog, yeast)
chr5_-_29782945 0.79 ENSDART00000125381
grass carp reovirus (GCRV)-induced gene 2o
chr19_+_7254917 0.78 ENSDART00000123934
hydroxysteroid (17-beta) dehydrogenase 8
chr8_-_21039978 0.78 ENSDART00000137606
ENSDART00000146532
zgc:112962
chr5_-_5848617 0.77

chr5_+_34863545 0.77 ENSDART00000131286
ER lipid raft associated 2
chr24_+_19065679 0.77 ENSDART00000139299
zgc:162928
KN150034v1_+_1223 0.76

chr5_-_29782972 0.76 ENSDART00000125381
grass carp reovirus (GCRV)-induced gene 2o
chr7_+_23881828 0.75 ENSDART00000076735
low density lipoprotein receptor-related protein 10
chr7_-_600388 0.75

chr1_+_43822319 0.74 ENSDART00000147702
zinc finger, DHHC-type containing 5a
chr8_+_52544578 0.74 ENSDART00000127729
STAM binding protein b
chr6_+_50382153 0.74 ENSDART00000055504
cytochrome c-1
chr17_+_24045582 0.73 ENSDART00000132755
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2b
chr7_+_39812659 0.72 ENSDART00000099046
ENSDARG00000036489
chr3_-_19913207 0.72

chr23_-_19560269 0.71 ENSDART00000009092
family with sequence similarity 208, member Ab
chr25_+_3423586 0.70 ENSDART00000166312
coiled-coil domain containing 77
chr3_+_58417635 0.70 ENSDART00000154122
si:ch211-165g14.1
chr13_+_22973830 0.70 ENSDART00000110266
phosphoinositide-3-kinase adaptor protein 1
chr2_-_16690351 0.68 ENSDART00000057216
Rho guanine nucleotide exchange factor (GEF) 4
chr4_+_26064174 0.68 ENSDART00000171204
SCY1 like pseudokinase 2
chr17_-_16316519 0.68 ENSDART00000170091
homeobox containing 1a
chr22_-_38472879 0.67 ENSDART00000149683
protein tyrosine kinase 7a
chr17_-_16316442 0.67 ENSDART00000170091
homeobox containing 1a
chr5_+_25474996 0.67 ENSDART00000098473
Kruppel-like factor 9
chr3_+_52745606 0.67 ENSDART00000104683
pre-B-cell leukemia transcription factor 4
chr5_-_18459312 0.67 ENSDART00000145210
ankyrin repeat and LEM domain containing 2
chr2_-_22875246 0.67 ENSDART00000159641
zinc finger protein 644a
chr7_+_71585147 0.67 ENSDART00000161344
NOL1/NOP2/Sun domain family, member 6
chr4_+_71390404 0.66 ENSDART00000174116
zgc:152938
chr9_+_55395276 0.66 ENSDART00000029528
motile sperm domain containing 2
chr14_+_22160235 0.66 ENSDART00000019296
growth differentiation factor 9
chr1_-_44649941 0.66 ENSDART00000110390
ENSDARG00000025518
chr10_+_16543577 0.65 ENSDART00000121864
solute carrier family 27 (fatty acid transporter), member 6
chr16_-_40508938 0.65 ENSDART00000032389
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr9_-_28588192 0.64 ENSDART00000104317
ENSDART00000064343
Kruppel-like factor 7b
chr13_-_25620394 0.64 ENSDART00000111567
sphingosine-1-phosphate lyase 1
chr21_-_14079056 0.63 ENSDART00000111659
deafness, autosomal recessive 31a
chr16_+_11351423 0.63 ENSDART00000138335
glycogen synthase kinase 3 alpha b
chr17_+_43916865 0.63 ENSDART00000049503
pellino E3 ubiquitin protein ligase family member 2
chr14_+_21457220 0.62 ENSDART00000111839
lysine (K)-specific demethylase 2Ab
chr5_+_25475041 0.62 ENSDART00000098473
Kruppel-like factor 9
chr7_+_23224924 0.62 ENSDART00000142401
zgc:109889
chr7_-_60046465 0.62 ENSDART00000127518
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr8_-_49217824 0.61

chr3_+_15679209 0.61 ENSDART00000104397
transmembrane protein 11
chr11_-_37816180 0.61 ENSDART00000086516
kelch domain containing 8A
chr17_-_23874694 0.61 ENSDART00000122108
PDZ domain containing 8
chr25_+_7358777 0.61 ENSDART00000161593
phosphatidylserine synthase 2
chr5_-_18458827 0.60 ENSDART00000145210
ankyrin repeat and LEM domain containing 2
chr7_+_23224800 0.60 ENSDART00000115299
ENSDART00000101423
zgc:109889
chr17_-_32417510 0.60 ENSDART00000145487
Kruppel-like factor 11b
chr8_-_25826973 0.60 ENSDART00000047008
ENSDART00000128829
EF-hand domain family, member D2
chr1_+_43822153 0.60 ENSDART00000147702
zinc finger, DHHC-type containing 5a
chr14_+_21522672 0.59 ENSDART00000122739
C-terminal binding protein 1
chr8_+_16722505 0.58 ENSDART00000133514
ELOVL fatty acid elongase 7a
chr23_-_10851353 0.58 ENSDART00000055038
RING1 and YY1 binding protein a
chr25_+_11212787 0.58 ENSDART00000159583
ENSDARG00000099473
chr15_+_19399898 0.57 ENSDART00000143632
acyl-CoA dehydrogenase family, member 8
chr22_-_6490288 0.57 ENSDART00000149676
ENSDARG00000095952
chr21_-_35291005 0.57 ENSDART00000134780
ubiquitin-like domain containing CTD phosphatase 1
chr18_-_16948109 0.56 ENSDART00000100117
zinc finger protein 143b
chr12_-_4597080 0.56 ENSDART00000110514
proline rich 12a
chr25_-_16685648 0.56 ENSDART00000019413
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9a
chr2_-_56632969 0.56 ENSDART00000089158
histocompatibility (minor) HA-1 a
chr18_+_439402 0.55 ENSDART00000167841
synovial sarcoma translocation gene on chromosome 18-like 2
chr2_+_35750334 0.55 ENSDART00000052666
RAS protein activator like 2
chr13_-_25620444 0.55 ENSDART00000111567
sphingosine-1-phosphate lyase 1
chr12_+_19199002 0.54 ENSDART00000066389
transmembrane protein 184ba
chr9_-_28588228 0.53 ENSDART00000104317
ENSDART00000064343
Kruppel-like factor 7b
chr7_-_60046429 0.52 ENSDART00000127518
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr7_+_39812732 0.52 ENSDART00000099046
ENSDARG00000036489
chr23_+_6652502 0.52 ENSDART00000081763
RNA binding motif protein 38
chr13_+_32323952 0.52 ENSDART00000057421
retinol dehydrogenase 14a (all-trans/9-cis/11-cis)
chr13_+_35799851 0.52 ENSDART00000046115
major facilitator superfamily domain containing 2aa
chr5_-_19428718 0.51 ENSDART00000088881
ENSDART00000168053
G protein-coupled receptor kinase interacting ArfGAP 2a
chr10_-_35164761 0.51 ENSDART00000049633
zgc:110006
chr4_-_16893974 0.51 ENSDART00000124627
serine/threonine kinase receptor associated protein
chr14_+_21835107 0.51 ENSDART00000109065
cyclin G1
chr12_+_2769741 0.51 ENSDART00000178262
MMS19 homolog, cytosolic iron-sulfur assembly component
chr7_+_39812522 0.50 ENSDART00000099046
ENSDARG00000036489
chr17_+_24045786 0.50 ENSDART00000132755
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2b
chr9_-_55395115 0.50

chr1_-_24453469 0.49 ENSDART00000132355
F-box and WD repeat domain containing 7
chr15_-_35020250 0.49 ENSDART00000154094
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase a
chr20_+_51918642 0.48 ENSDART00000010271
axin interactor, dorsalization associated

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.9 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040)
0.8 5.7 GO:0070987 error-free translesion synthesis(GO:0070987)
0.8 3.0 GO:0051977 maintenance of blood-brain barrier(GO:0035633) lysophospholipid transport(GO:0051977) lipid transport across blood brain barrier(GO:1990379)
0.7 5.8 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.5 1.5 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.4 1.8 GO:0046098 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine metabolic process(GO:0046098) guanine biosynthetic process(GO:0046099) hypoxanthine metabolic process(GO:0046100)
0.4 1.2 GO:1902908 regulation of melanosome transport(GO:1902908)
0.4 2.3 GO:0030237 female sex determination(GO:0030237)
0.4 3.1 GO:0046850 regulation of bone remodeling(GO:0046850)
0.4 1.2 GO:0043116 negative regulation of vascular permeability(GO:0043116) negative regulation of calcium ion import(GO:0090281)
0.4 1.9 GO:0006828 manganese ion transport(GO:0006828)
0.3 1.4 GO:0006407 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
0.3 2.5 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.3 1.2 GO:0010985 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916) regulation of lipoprotein particle clearance(GO:0010984) negative regulation of lipoprotein particle clearance(GO:0010985)
0.3 0.8 GO:1903894 regulation of endoplasmic reticulum unfolded protein response(GO:1900101) negative regulation of endoplasmic reticulum unfolded protein response(GO:1900102) regulation of IRE1-mediated unfolded protein response(GO:1903894) negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.2 1.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 1.0 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.2 1.9 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.2 1.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.2 1.2 GO:0017145 stem cell division(GO:0017145)
0.2 0.8 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.2 1.8 GO:0097345 positive regulation of mitochondrial membrane permeability(GO:0035794) mitochondrial outer membrane permeabilization(GO:0097345) positive regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902110) mitochondrial outer membrane permeabilization involved in programmed cell death(GO:1902686)
0.2 0.6 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 0.5 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168)
0.1 0.5 GO:0031642 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.1 0.8 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.3 GO:0072003 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.1 1.0 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.9 GO:0021634 optic nerve formation(GO:0021634)
0.1 1.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 1.3 GO:0090398 cellular senescence(GO:0090398)
0.1 1.2 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.1 1.3 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 1.4 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 0.8 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.7 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.5 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.1 1.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 1.5 GO:0048538 thymus development(GO:0048538)
0.1 1.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 1.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.9 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.4 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.2 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.0 0.2 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.0 2.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 1.2 GO:0046466 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.0 1.0 GO:0015908 fatty acid transport(GO:0015908)
0.0 0.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 1.6 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.2 GO:0030262 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.8 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.8 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 1.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.0 3.2 GO:0006936 muscle contraction(GO:0006936)
0.0 0.8 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.6 GO:0097192 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 0.6 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.3 GO:0060036 notochord cell vacuolation(GO:0060036)
0.0 0.5 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 1.1 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.6 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.6 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.7 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.2 GO:0031268 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.8 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.4 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.1 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 1.5 GO:0016573 histone acetylation(GO:0016573)
0.0 1.2 GO:0016579 protein deubiquitination(GO:0016579)
0.0 1.4 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.5 GO:0039021 pronephric glomerulus development(GO:0039021)
0.0 0.2 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 3.5 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.7 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 0.1 GO:0003356 regulation of cilium beat frequency(GO:0003356) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.3 1.5 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.2 0.5 GO:0097361 CIA complex(GO:0097361)
0.2 0.8 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.2 0.8 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 1.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.7 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.9 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 0.2 GO:0034991 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 1.2 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.7 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.7 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.2 GO:0097546 ciliary base(GO:0097546)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.0 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 1.0 GO:0005844 polysome(GO:0005844)
0.0 3.3 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.9 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.2 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.0 0.5 GO:0030663 COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663)
0.0 1.7 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.5 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 1.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.7 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.7 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 1.4 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 2.2 GO:0005813 centrosome(GO:0005813)
0.0 0.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.9 GO:0005911 cell-cell junction(GO:0005911)
0.0 7.2 GO:0005615 extracellular space(GO:0005615)
0.0 3.8 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 6.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.2 GO:0005930 axoneme(GO:0005930)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 5.4 GO:0005794 Golgi apparatus(GO:0005794)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.7 GO:0017125 deoxycytidyl transferase activity(GO:0017125)
1.0 3.0 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.8 3.0 GO:0051978 lysophospholipid transporter activity(GO:0051978)
0.6 1.8 GO:0052657 guanine phosphoribosyltransferase activity(GO:0052657)
0.5 4.6 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.4 5.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.4 1.2 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.4 1.2 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.4 2.3 GO:0070698 type I activin receptor binding(GO:0070698)
0.3 1.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.3 1.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.3 1.2 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.3 2.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 1.2 GO:0048019 receptor antagonist activity(GO:0048019)
0.2 0.7 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.2 1.9 GO:0016530 metallochaperone activity(GO:0016530)
0.2 2.5 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.2 1.5 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.2 1.1 GO:0043295 glutathione binding(GO:0043295)
0.1 1.3 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 1.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 2.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.9 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 1.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 1.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 1.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 1.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.6 GO:0022884 protein transmembrane transporter activity(GO:0008320) macromolecule transmembrane transporter activity(GO:0022884)
0.1 0.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.3 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.1 0.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 1.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.8 GO:0048038 quinone binding(GO:0048038)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.6 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 1.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 1.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.5 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 1.0 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.8 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 1.1 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 2.3 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.5 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.6 GO:0032452 histone demethylase activity(GO:0032452)
0.0 6.1 GO:0003924 GTPase activity(GO:0003924)
0.0 0.7 GO:0009055 electron carrier activity(GO:0009055)
0.0 1.2 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 2.1 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.1 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 1.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 1.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 1.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 2.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 0.5 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 3.0 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.7 PID ATM PATHWAY ATM pathway
0.0 0.5 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.8 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 1.4 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.2 3.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 2.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 0.9 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 0.6 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.2 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 1.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 5.6 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 2.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.8 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis