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Results for foxo3b+foxo6a+foxo6b

Z-value: 1.48

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Transcription factors associated with foxo3b+foxo6a+foxo6b

Gene Symbol Gene ID Gene Info
foxo6b
ENSDARG00000024619 forkhead box O6 b
foxo3b
ENSDARG00000042904 forkhead box O3b
foxo6a
ENSDARG00000100486 forkhead box O6 a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxo3bdr10_dc_chr20_-_32429820_32429890-0.894.8e-06Click!
si:ch211-206a7.2dr10_dc_chr19_+_15666408_15666441-0.783.8e-04Click!

Activity profile of foxo3b+foxo6a+foxo6b motif

Sorted Z-values of foxo3b+foxo6a+foxo6b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of foxo3b+foxo6a+foxo6b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr7_-_19989384 5.33 ENSDART00000173619
si:ch73-335l21.4
si:ch73-335l21.4
chr10_-_25608902 4.84 ENSDART00000147876
grik1a
glutamate receptor, ionotropic, kainate 1a
chr15_+_38397772 4.53 ENSDART00000142403
si:dkey-24p1.6
si:dkey-24p1.6
chr24_-_14446593 4.19

chr23_+_28396415 3.91 ENSDART00000142179
birc5b
baculoviral IAP repeat containing 5b
chr24_+_19270877 3.78

chr7_+_29969850 3.59 ENSDART00000109243
sema4bb
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Bb
chr3_+_44928323 3.46 ENSDART00000170913
zgc:112146
zgc:112146
chr7_-_19989419 3.41 ENSDART00000127699
si:ch73-335l21.4
si:ch73-335l21.4
chr5_+_29052293 3.36 ENSDART00000035400
tsc1a
tuberous sclerosis 1a
chr10_-_7513764 3.35 ENSDART00000167054
ENSDART00000167706
nrg1
neuregulin 1
chr5_-_11530803 3.31 ENSDART00000159896
gatsl3
GATS protein-like 3
chr5_-_25133229 2.83 ENSDART00000051566
zgc:101016
zgc:101016
chr22_-_6916274 2.81

chr5_-_17372745 2.73 ENSDART00000141978
si:dkey-112e17.1
si:dkey-112e17.1
chr6_+_29763568 2.66 ENSDART00000151784
ptmaa
prothymosin, alpha a
chr12_+_18849010 2.65 ENSDART00000078494
l3mbtl2
l(3)mbt-like 2 (Drosophila)
chr9_-_12603178 2.55

chr2_-_7260067 2.55 ENSDART00000092116
extl2
exostosin-like glycosyltransferase 2
chr12_+_18848952 2.51 ENSDART00000153235
l3mbtl2
l(3)mbt-like 2 (Drosophila)
chr2_-_37495925 2.49 ENSDART00000146103
dapk3
death-associated protein kinase 3
chr7_-_19713757 2.43

chr20_+_34091702 2.41 ENSDART00000061729
si:dkey-97o5.1
si:dkey-97o5.1
chr14_-_47387481 2.32 ENSDART00000031498
ccna2
cyclin A2
chr10_+_33790718 2.32 ENSDART00000161430
rxfp2a
relaxin/insulin-like family peptide receptor 2a
chr21_-_17001108 2.32 ENSDART00000101263
ube2g1b
ubiquitin-conjugating enzyme E2G 1b (UBC7 homolog, yeast)
chr12_+_47729417 2.24 ENSDART00000159120
polr3a
polymerase (RNA) III (DNA directed) polypeptide A
chr7_-_29084775 2.15 ENSDART00000075757
gtf2a2
general transcription factor IIA, 2
chr7_+_69211965 2.09 ENSDART00000028064
ctdnep1b
CTD nuclear envelope phosphatase 1b
chr17_+_28653205 2.05 ENSDART00000129779
hectd1
HECT domain containing 1
chr4_-_12782246 2.04 ENSDART00000058020
helb
helicase (DNA) B
chr8_+_47565879 2.04

chr2_+_21698627 2.03 ENSDART00000133228
ctdsplb
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like b
chr6_-_22060441 2.03 ENSDART00000167167
utp6
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr9_-_12603215 2.01

chr15_+_38397715 1.97 ENSDART00000142403
si:dkey-24p1.6
si:dkey-24p1.6
chr5_+_29052517 1.92 ENSDART00000035400
tsc1a
tuberous sclerosis 1a
chr7_+_36281268 1.91 ENSDART00000173682
chd9
chromodomain helicase DNA binding protein 9
chr9_+_27909662 1.91 ENSDART00000112415
lcmt2
leucine carboxyl methyltransferase 2
chr11_+_24806542 1.85 ENSDART00000018743
phf20a
PHD finger protein 20, a
chr21_-_41148147 1.85 ENSDART00000169977
bnip1b
BCL2/adenovirus E1B interacting protein 1b
chr21_-_17001152 1.84 ENSDART00000101263
ube2g1b
ubiquitin-conjugating enzyme E2G 1b (UBC7 homolog, yeast)
chr13_-_25711537 1.83 ENSDART00000015154
papolg
poly(A) polymerase gamma
chr16_+_46443800 1.82 ENSDART00000131072
rpz2
rapunzel 2
chr17_-_29005489 1.76 ENSDART00000157210
CR925802.1
ENSDARG00000097263
chr5_+_25133592 1.76 ENSDART00000098467
abhd17b
abhydrolase domain containing 17B
chr7_-_36281088 1.74 ENSDART00000158224
CU464124.1
ENSDARG00000103315
chr8_-_53165501 1.74 ENSDART00000135982
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr25_-_34648876 1.73 ENSDART00000154851
zgc:153405
zgc:153405
chr19_-_20026445 1.71 ENSDART00000160002
tax1bp1a
Tax1 (human T-cell leukemia virus type I) binding protein 1a
chr6_-_41141242 1.69 ENSDART00000128723
ENSDART00000151055
slc6a22.1
solute carrier family 6 member 22, tandem duplicate 1
chr18_+_20571460 1.69 ENSDART00000151990
wee2
WEE1 homolog 2 (S. pombe)
chr2_+_22753634 1.64 ENSDART00000171853
LMO4
zgc:56628
chr3_+_27163495 1.63 ENSDART00000175278
ENSDART00000177526
BX908803.2
ENSDARG00000107836
chr5_+_29052462 1.62 ENSDART00000035400
tsc1a
tuberous sclerosis 1a
chr2_-_56632969 1.62 ENSDART00000089158
hmha1a
histocompatibility (minor) HA-1 a
chr7_+_31750808 1.56 ENSDART00000173848
mettl15
methyltransferase like 15
chr14_+_46362661 1.55 ENSDART00000025749
ttc9c
tetratricopeptide repeat domain 9C
chr7_+_29970029 1.55 ENSDART00000109243
sema4bb
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Bb
chr23_+_28213261 1.50 ENSDART00000143362
BX663515.1
ENSDARG00000094837
chr2_-_38097978 1.49 ENSDART00000056544
tox4a
TOX high mobility group box family member 4 a
chr15_+_38397897 1.48 ENSDART00000142403
si:dkey-24p1.6
si:dkey-24p1.6
chr16_-_29470341 1.46 ENSDART00000149289
tlr18
toll-like receptor 18
chr18_+_20571400 1.44 ENSDART00000151990
wee2
WEE1 homolog 2 (S. pombe)
chr6_-_41141280 1.42 ENSDART00000001861
slc6a22.1
solute carrier family 6 member 22, tandem duplicate 1
chr7_+_31750775 1.39 ENSDART00000173848
mettl15
methyltransferase like 15
chr23_-_36547458 1.38 ENSDART00000006881
zbtb39
zinc finger and BTB domain containing 39
KN150034v1_+_1223 1.37

chr3_-_22240424 1.36

chr22_+_18294579 1.35 ENSDART00000033103
gatad2ab
GATA zinc finger domain containing 2Ab
chr20_-_7079949 1.34 ENSDART00000040793
sirt5
sirtuin 5
chr21_+_17265099 1.33 ENSDART00000145057
tsc1b
tuberous sclerosis 1b
chr22_+_18294622 1.30 ENSDART00000033103
gatad2ab
GATA zinc finger domain containing 2Ab
chr19_+_20027309 1.28 ENSDART00000165934
hibadha
3-hydroxyisobutyrate dehydrogenase a
chr7_+_69211741 1.23 ENSDART00000109644
ctdnep1b
CTD nuclear envelope phosphatase 1b
chr12_+_17481598 1.22 ENSDART00000170449
ENSDART00000111565
pms2
PMS1 homolog 2, mismatch repair system component
chr19_-_7522951 1.19 ENSDART00000003544
gabpb2a
GA binding protein transcription factor, beta subunit 2a
chr18_+_20571513 1.19 ENSDART00000136710
wee2
WEE1 homolog 2 (S. pombe)
chr5_-_11531015 1.19 ENSDART00000159896
gatsl3
GATS protein-like 3
chr16_-_29470491 1.19 ENSDART00000175571
tlr18
toll-like receptor 18
chr12_-_4444385 1.16 ENSDART00000092492
si:ch211-173d10.1
si:ch211-173d10.1
chr23_+_28213293 1.16 ENSDART00000143362
BX663515.1
ENSDARG00000094837
chr21_-_13026036 1.15 ENSDART00000135623
fam219aa
family with sequence similarity 219, member Aa
chr19_-_7522853 1.14 ENSDART00000168194
gabpb2a
GA binding protein transcription factor, beta subunit 2a
chr7_+_69212144 1.10 ENSDART00000159799
ctdnep1b
CTD nuclear envelope phosphatase 1b
chr13_-_12898069 1.09 ENSDART00000009499
whsc1
Wolf-Hirschhorn syndrome candidate 1
chr19_-_13368170 1.06 ENSDART00000158330
zfpm2b
zinc finger protein, FOG family member 2b
chr24_-_38221052 1.05

chr20_-_7079708 1.04 ENSDART00000040793
sirt5
sirtuin 5
chr7_-_41601001 1.03 ENSDART00000174258
zgc:92818
zgc:92818
chr23_-_903314 1.01 ENSDART00000165102
rhoac
ras homolog gene family, member Ac
chr20_-_3385325 1.00 ENSDART00000092264
rev3l
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr2_+_22753590 0.98 ENSDART00000171853
LMO4
zgc:56628
chr16_-_25485248 0.94 ENSDART00000040756
zgc:136493
zgc:136493
chr23_+_44937093 0.92

chr12_+_28685081 0.91 ENSDART00000022724
pnpo
pyridoxamine 5'-phosphate oxidase
KN150034v1_+_1158 0.89

chr22_+_2517235 0.89 ENSDART00000147967
si:ch73-92e7.4
si:ch73-92e7.4
chr5_-_11530880 0.86 ENSDART00000159896
gatsl3
GATS protein-like 3
chr11_+_41307205 0.86

chr2_-_38098036 0.84 ENSDART00000056544
tox4a
TOX high mobility group box family member 4 a
chr24_-_14446522 0.84

chr14_-_47387082 0.83

chr21_-_19649065 0.82 ENSDART00000131562
ENSDART00000133467
BX927394.1
ENSDARG00000092538
chr12_+_47729272 0.77 ENSDART00000159120
polr3a
polymerase (RNA) III (DNA directed) polypeptide A
chr6_-_57479549 0.76 ENSDART00000128065
ddx27
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
chr15_-_19398601 0.75 ENSDART00000062576
thyn1
thymocyte nuclear protein 1
KN150232v1_+_13079 0.74 ENSDART00000174701
CABZ01084889.1
ENSDARG00000107269
chr13_-_10214396 0.72 ENSDART00000132231
AL929457.1
ENSDARG00000095483
chr3_+_33788977 0.72 ENSDART00000055248
alkbh7
alkB homolog 7
chr2_-_56632913 0.70 ENSDART00000089158
hmha1a
histocompatibility (minor) HA-1 a
chr8_+_26838596 0.70

chr21_-_13026077 0.68 ENSDART00000024616
fam219aa
family with sequence similarity 219, member Aa
chr5_-_25133456 0.64 ENSDART00000051566
zgc:101016
zgc:101016
chr5_-_23171454 0.64 ENSDART00000135153
TBC1D8B
TBC1 domain family member 8B
chr7_+_36280848 0.63 ENSDART00000027807
chd9
chromodomain helicase DNA binding protein 9
chr7_+_31750514 0.62 ENSDART00000173976
mettl15
methyltransferase like 15
chr16_-_29470444 0.58 ENSDART00000175571
tlr18
toll-like receptor 18
chr20_+_42993675 0.57 ENSDART00000153240
ENSDART00000134855
efr3bb
EFR3 homolog Bb (S. cerevisiae)
chr9_+_426701 0.56 ENSDART00000164310
bzw1b
basic leucine zipper and W2 domains 1b
chr15_-_46501789 0.56 ENSDART00000099185
ilkap
integrin-linked kinase-associated serine/threonine phosphatase
chr20_+_41904897 0.53 ENSDART00000139805
mcm9
minichromosome maintenance 9 homologous recombination repair factor
chr11_-_21243422 0.53 ENSDART00000080116
ikbke
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr23_-_12223670 0.52 ENSDART00000135035
fam217b
family with sequence similarity 217, member B
chr25_+_4729095 0.51 ENSDART00000163839
ap4e1
adaptor-related protein complex 4, epsilon 1 subunit
chr13_-_12898263 0.51 ENSDART00000009499
whsc1
Wolf-Hirschhorn syndrome candidate 1
chr22_-_10410949 0.51 ENSDART00000111962
ENSDART00000064809
nol8
nucleolar protein 8
chr19_-_20026359 0.51 ENSDART00000171664
tax1bp1a
Tax1 (human T-cell leukemia virus type I) binding protein 1a
chr13_-_48068159 0.50 ENSDART00000165157
CU468002.1
ENSDARG00000103616
chr10_+_45056951 0.47 ENSDART00000158553
ENSDARG00000101143
ENSDARG00000101143
chr7_-_19714367 0.46 ENSDART00000010932
snx15
sorting nexin 15
chr18_-_21921898 0.45 ENSDART00000132381
edc4
enhancer of mRNA decapping 4
chr16_+_29651305 0.45 ENSDART00000124232
mcl1b
MCL1, BCL2 family apoptosis regulator b
chr15_-_8215797 0.43 ENSDART00000156663
bach1a
BTB and CNC homology 1, basic leucine zipper transcription factor 1 a
chr3_-_4648706 0.42

chr15_-_19398506 0.42 ENSDART00000062576
thyn1
thymocyte nuclear protein 1
chr15_-_46501920 0.36 ENSDART00000099185
ilkap
integrin-linked kinase-associated serine/threonine phosphatase
chr8_-_16428630 0.33 ENSDART00000098691
rnf11b
ring finger protein 11b
chr5_-_43219303 0.32 ENSDART00000022481
mccc2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr2_-_44346715 0.30 ENSDART00000140633
sdhc
succinate dehydrogenase complex, subunit C, integral membrane protein
chr24_-_24884852 0.29 ENSDART00000122997
nup58
nucleoporin 58
chr19_+_21783204 0.28 ENSDART00000024639
tshz1
teashirt zinc finger homeobox 1
chr13_+_48067433 0.27 ENSDART00000171080
msh6
mutS homolog 6 (E. coli)
chr14_-_6096120 0.27

chr15_-_21756778 0.26 ENSDART00000039865
sdhdb
succinate dehydrogenase complex, subunit D, integral membrane protein b
chr8_+_17975195 0.26 ENSDART00000039887
ENSDART00000121984
ssbp3b
single stranded DNA binding protein 3b
chr14_-_31675157 0.26

chr23_+_17952613 0.24 ENSDART00000156331
si:ch73-390p7.2
si:ch73-390p7.2
chr20_+_41904703 0.24 ENSDART00000139805
mcm9
minichromosome maintenance 9 homologous recombination repair factor
chr16_-_31393328 0.23 ENSDART00000178298
mroh1
maestro heat-like repeat family member 1
chr10_-_38582881 0.22 ENSDART00000157222
BX000451.1
ENSDARG00000097896
chr18_+_21124045 0.22 ENSDART00000060191
suv420h1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr6_-_3837266 0.20 ENSDART00000059212
unc50
unc-50 homolog (C. elegans)
chr9_+_426850 0.19 ENSDART00000164310
bzw1b
basic leucine zipper and W2 domains 1b
KN150648v1_+_877 0.19

chr25_-_34622553 0.18 ENSDART00000125128
FP236630.1
ENSDARG00000086304
chr5_+_38126649 0.17 ENSDART00000138484
ENSDART00000142867
si:dkey-58f10.7
si:dkey-58f10.7
chr6_-_57479360 0.13 ENSDART00000128065
ddx27
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
chr3_+_42217445 0.13 ENSDART00000168228
tmem184a
transmembrane protein 184a
chr3_+_60367511 0.12 ENSDART00000128260
CABZ01087514.1
ENSDARG00000090861
chr6_+_22060547 0.12 ENSDART00000165271
suz12b
SUZ12 polycomb repressive complex 2b subunit
chr6_+_55835894 0.10 ENSDART00000108786
si:ch211-81n22.1
si:ch211-81n22.1
chr18_-_44533391 0.09 ENSDART00000077125
aplp2
amyloid beta (A4) precursor-like protein 2
chr16_+_10950751 0.06 ENSDART00000128762
dedd1
death effector domain-containing 1
chr15_+_42329433 0.06 ENSDART00000130404
scaf4b
SR-related CTD-associated factor 4b
chr7_+_25735735 0.02 ENSDART00000112908
pelp1
proline, glutamate and leucine rich protein 1
chr23_+_44622486 0.01 ENSDART00000014691
eif4e2rs1
eukaryotic translation initiation factor 4E family member 2 related sequence 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0051311 meiotic metaphase plate congression(GO:0051311)
1.1 3.3 GO:0008347 glial cell migration(GO:0008347) eurydendroid cell differentiation(GO:0021755)
0.9 4.3 GO:0060631 regulation of meiosis I(GO:0060631)
0.7 8.2 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.6 4.4 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.6 2.4 GO:0036048 regulation of ketone biosynthetic process(GO:0010566) protein demalonylation(GO:0036046) peptidyl-lysine demalonylation(GO:0036047) protein desuccinylation(GO:0036048) peptidyl-lysine desuccinylation(GO:0036049) protein deglutarylation(GO:0061698)
0.6 2.3 GO:0030801 positive regulation of cyclic nucleotide metabolic process(GO:0030801) positive regulation of cyclic nucleotide biosynthetic process(GO:0030804) positive regulation of nucleotide biosynthetic process(GO:0030810) positive regulation of cyclase activity(GO:0031281) positive regulation of lyase activity(GO:0051349) positive regulation of purine nucleotide biosynthetic process(GO:1900373)
0.5 2.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.5 1.9 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.3 1.3 GO:0006574 valine catabolic process(GO:0006574)
0.2 0.9 GO:0042823 water-soluble vitamin biosynthetic process(GO:0042364) pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.2 3.6 GO:0070475 rRNA base methylation(GO:0070475)
0.2 4.8 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.2 3.2 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.1 0.6 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 1.8 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 2.1 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 1.0 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 5.0 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.1 1.5 GO:0006298 mismatch repair(GO:0006298)
0.1 0.4 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.7 GO:0070265 necrotic cell death(GO:0070265) programmed necrotic cell death(GO:0097300)
0.1 2.0 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 1.8 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.1 1.6 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 2.0 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 0.3 GO:0006552 leucine catabolic process(GO:0006552)
0.0 3.1 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 1.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 2.3 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.4 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 1.7 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 4.2 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.9 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.8 GO:0032508 DNA geometric change(GO:0032392) DNA duplex unwinding(GO:0032508)
0.0 2.5 GO:0010942 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.0 7.3 GO:0016567 protein ubiquitination(GO:0016567)
0.0 6.6 GO:0045892 negative regulation of transcription, DNA-templated(GO:0045892)
0.0 0.1 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 2.6 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.8 2.3 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.6 4.4 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.4 1.2 GO:0032389 MutLalpha complex(GO:0032389)
0.4 2.0 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.3 2.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 2.6 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.6 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 3.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.3 GO:1905202 methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1 3.9 GO:0005876 spindle microtubule(GO:0005876)
0.1 1.0 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.3 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.8 GO:0042555 MCM complex(GO:0042555)
0.0 0.5 GO:0044545 NSL complex(GO:0044545)
0.0 1.7 GO:0031201 SNARE complex(GO:0031201)
0.0 2.1 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 1.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.5 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 10.6 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 3.5 GO:0005730 nucleolus(GO:0005730)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0071424 rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424)
0.7 3.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.7 2.7 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.6 2.4 GO:0061697 protein-malonyllysine demalonylase activity(GO:0036054) protein-succinyllysine desuccinylase activity(GO:0036055) protein-glutaryllysine deglutarylase activity(GO:0061697)
0.5 1.8 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.4 3.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.4 4.8 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.3 3.9 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.2 0.9 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2 2.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 2.0 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.2 5.2 GO:0035064 methylated histone binding(GO:0035064)
0.2 2.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 1.5 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 1.8 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 5.0 GO:0045499 chemorepellent activity(GO:0045499)
0.1 4.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 2.0 GO:0030515 snoRNA binding(GO:0030515)
0.1 0.3 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 3.0 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 0.9 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.3 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 4.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.3 GO:0048039 ubiquinone binding(GO:0048039)
0.1 5.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 2.3 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.1 1.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.9 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 2.5 GO:0003678 DNA helicase activity(GO:0003678)
0.0 3.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 1.3 GO:0050661 NADP binding(GO:0050661)
0.0 2.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.4 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.7 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 1.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.9 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 2.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.6 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 2.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.3 3.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 3.0 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 2.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.5 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 2.1 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.0 REACTOME DNA REPAIR Genes involved in DNA Repair