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DANIO-CODE

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Results for foxo4

Z-value: 1.26

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Transcription factors associated with foxo4

Gene Symbol Gene ID Gene Info
ENSDARG00000055792 forkhead box O4

Activity profile of foxo4 motif

Sorted Z-values of foxo4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of foxo4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_-_32636372 5.41 ENSDART00000085512
ENSDART00000144694
KN motif and ankyrin repeat domains 1b
chr1_-_7160294 4.01 ENSDART00000174972
ENSDARG00000108483
chr15_+_20054306 3.88 ENSDART00000155199
zgc:112083
chr22_-_28828375 3.38 ENSDART00000104880
ENSDART00000005112
si:dkeyp-34c12.1
chr11_-_25019899 3.16 ENSDART00000123567
snail family zinc finger 1a
chr1_-_7160099 3.13 ENSDART00000174972
ENSDARG00000108483
chr14_+_14850200 3.03 ENSDART00000167966
zgc:158852
chr8_+_37716781 2.95 ENSDART00000108556
nucleophosmin/nucleoplasmin, 2a
chr16_-_13723352 2.83 ENSDART00000139102
D site albumin promoter binding protein b
chr1_-_8593850 2.75 ENSDART00000146065
ENSDART00000114876
ubinuclein 1
chr13_-_25711537 2.73 ENSDART00000015154
poly(A) polymerase gamma
chr7_+_45747622 2.43 ENSDART00000163991
cyclin E1
chr19_+_5399535 2.35 ENSDART00000145749
si:dkeyp-113d7.1
chr7_+_45747395 2.34 ENSDART00000163991
cyclin E1
chr9_-_12687806 2.31 ENSDART00000058565
PTTG1 interacting protein b
chr3_-_15325357 2.29 ENSDART00000139575
spinster homolog 1 (Drosophila)
chr9_-_21677941 2.19 ENSDART00000121939
ENSDART00000080404
M-phase phosphoprotein 8
chr6_-_8008902 2.16 ENSDART00000151358
ral guanine nucleotide dissociation stimulator-like 3a
chr18_-_20476969 2.13 ENSDART00000060311
progestin and adipoQ receptor family member Va
chr17_+_14957568 2.13 ENSDART00000066604
G protein-coupled receptor 137c
chr25_-_7794186 2.11 ENSDART00000104686
autophagy/beclin-1 regulator 1b
chr23_-_1562572 2.11 ENSDART00000013635
F-box protein 30b
chr2_-_30216377 2.04 ENSDART00000130142
ubiquitin-conjugating enzyme E2W (putative)
chr16_-_26947117 1.99 ENSDART00000111156
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr11_-_44859225 1.95 ENSDART00000163776
eukaryotic translation initiation factor 4A3
chr17_-_9806363 1.93 ENSDART00000021942
e2f-associated phosphoprotein
chr7_+_28824986 1.93 ENSDART00000052349
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr21_+_20350152 1.92 ENSDART00000144366
si:dkey-30k6.5
chr16_-_13723295 1.92 ENSDART00000139102
D site albumin promoter binding protein b
chr24_+_26223767 1.92

chr17_+_33205930 1.89 ENSDART00000104476
sorting nexin 9a
chr23_-_36349563 1.89

chr4_-_14208573 1.87 ENSDART00000015134
twinfilin actin-binding protein 1b
chr8_+_26015379 1.85 ENSDART00000142555
ariadne homolog 2 (Drosophila)
chr5_+_3567992 1.85 ENSDART00000129329
RPA interacting protein
chr17_+_33205732 1.82 ENSDART00000104476
sorting nexin 9a
chr21_+_20350218 1.79 ENSDART00000144366
si:dkey-30k6.5
chr22_-_29740287 1.79 ENSDART00000166002
programmed cell death 4b
chr2_-_30216333 1.79 ENSDART00000130142
ubiquitin-conjugating enzyme E2W (putative)
chr11_+_11136919 1.78 ENSDART00000026135
lymphocyte antigen 75
chr5_-_56254482 1.75 ENSDART00000014028
protein phosphatase, Mg2+/Mn2+ dependent, 1Db
chr13_+_12629211 1.74 ENSDART00000015127
zgc:100846
chr22_-_29740737 1.69 ENSDART00000009223
programmed cell death 4b
chr12_-_19063761 1.65 ENSDART00000153343
zinc finger CCCH-type containing 7B
chr20_-_53123124 1.61 ENSDART00000162812
farnesyl-diphosphate farnesyltransferase 1
chr7_-_51474531 1.61 ENSDART00000083190
histone deacetylase 8
chr14_+_41039244 1.57 ENSDART00000111480
BCL6 corepressor-like 1
chr5_-_22099244 1.55 ENSDART00000161298
non-POU domain containing, octamer-binding
chr5_-_66070385 1.55 ENSDART00000032909
K(lysine) acetyltransferase 5b
chr16_-_41764849 1.54 ENSDART00000084610
centrosomal protein 85
chr3_-_26060787 1.53 ENSDART00000113843
yippee-like 3
chr3_-_15529158 1.53 ENSDART00000080441
zgc:66443
chr15_+_27000467 1.51 ENSDART00000023842
protein phosphatase, Mg2+/Mn2+ dependent, 1Da
chr19_-_5186692 1.50 ENSDART00000037007
triosephosphate isomerase 1a
chr1_+_50547385 1.49 ENSDART00000132141
BTB (POZ) domain containing 3a
chr22_+_38322821 1.48 ENSDART00000104498
REST corepressor 3
chr2_+_58943872 1.44 ENSDART00000158860
ENSDART00000067736
serine/threonine kinase 11
chr23_-_3815871 1.44 ENSDART00000137826
high mobility group AT-hook 1a
chr15_+_34211736 1.42 ENSDART00000163513
ADP-ribosylation factor-like 4aa
chr14_+_26417614 1.41 ENSDART00000148216
polymerase (RNA) II (DNA directed) polypeptide G-like
chr7_+_28825033 1.41 ENSDART00000052349
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr6_-_8009143 1.41 ENSDART00000151358
ral guanine nucleotide dissociation stimulator-like 3a
chr22_+_23260371 1.40

chr15_+_19948916 1.39 ENSDART00000054416
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, b
chr15_-_14102102 1.37 ENSDART00000139068
zgc:114130
chr3_+_48810347 1.36 ENSDART00000133283
protein kinase C substrate 80K-H
chr6_+_38629054 1.33 ENSDART00000086533
ATPase, class V, type 10A
chr21_+_20350334 1.33 ENSDART00000144366
si:dkey-30k6.5
chr10_-_6587281 1.32 ENSDART00000163788
ENSDART00000171833
chromodomain helicase DNA binding protein 1
chr9_-_37557040 1.31 ENSDART00000039913
hspb associated protein 1
chr17_-_23689380 1.30 ENSDART00000124661
3'-phosphoadenosine 5'-phosphosulfate synthase 2a
chr10_+_32107014 1.30 ENSDART00000137373
si:ch211-266i6.3
chr5_+_44246311 1.30 ENSDART00000145299
ENSDART00000136521
KN motif and ankyrin repeat domains 1a
chr25_-_7794262 1.29 ENSDART00000156761
autophagy/beclin-1 regulator 1b
chr5_-_64432697 1.27 ENSDART00000165556
torsin family 2, member A
chr20_+_53563389 1.27 ENSDART00000060432
cell division cycle 40 homolog (S. cerevisiae)
chr16_-_5205600 1.26 ENSDART00000148955
branched chain keto acid dehydrogenase E1, beta polypeptide
chr24_-_6649190 1.25 ENSDART00000042478
enkurin, TRPC channel interacting protein
chr12_+_23691261 1.25 ENSDART00000066331
supervillin a
chr5_-_56254353 1.25 ENSDART00000014028
protein phosphatase, Mg2+/Mn2+ dependent, 1Db
chr20_+_1364879 1.24 ENSDART00000145981
ENSDART00000152709
methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
chr22_-_29740663 1.24 ENSDART00000009223
programmed cell death 4b
chr8_-_51612689 1.23 ENSDART00000175779
potassium channel tetramerization domain containing 9a
chr15_-_37687982 1.21 ENSDART00000154641
proline and serine rich 3
chr7_-_51474798 1.20 ENSDART00000175523
histone deacetylase 8
chr24_-_6649248 1.20 ENSDART00000042478
enkurin, TRPC channel interacting protein
chr17_+_32408151 1.19 ENSDART00000155519
si:ch211-139d20.3
chr21_+_19511167 1.19 ENSDART00000058487
retinoic acid induced 14
chr18_-_17158316 1.16 ENSDART00000141873
zinc finger CCCH-type containing 18
chr22_-_29695242 1.16

chr20_-_53123015 1.15 ENSDART00000162812
farnesyl-diphosphate farnesyltransferase 1
chr15_+_19948869 1.14 ENSDART00000054416
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, b
chr22_+_18840143 1.14

chr6_+_40925259 1.13 ENSDART00000002728
ENSDART00000145153
eukaryotic translation initiation factor 4E nuclear import factor 1
chr12_+_23691397 1.12 ENSDART00000066331
supervillin a
chr3_+_32279635 1.11 ENSDART00000141793
related RAS viral (r-ras) oncogene homolog
chr21_+_34053739 1.11 ENSDART00000147519
myotubularin related protein 1b
chr1_+_45148002 1.11 ENSDART00000148086
mitogen-activated protein kinase kinase 7
chr10_-_6587375 1.10 ENSDART00000163788
ENSDART00000171833
chromodomain helicase DNA binding protein 1
chr15_-_31103957 1.10 ENSDART00000080328
neurofibromin 1a
chr20_-_20711298 1.09 ENSDART00000063492
protein phosphatase, Mg2+/Mn2+ dependent, 1Ab
chr19_+_40750511 1.09 ENSDART00000147391
family with sequence similarity 133, member B
chr16_-_39317068 1.06 ENSDART00000133642
glycerol-3-phosphate dehydrogenase 1-like
chr21_-_32048130 1.05 ENSDART00000137878
methionine adenosyltransferase II, beta
chr4_-_1871246 1.05 ENSDART00000103484
growth arrest-specific 2 like 3
chr11_+_16017857 1.05 ENSDART00000081054
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr12_+_19999188 1.03

chr11_-_34314863 1.02 ENSDART00000133302
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a
chr2_-_31728072 1.01 ENSDART00000113498
leucine rich repeat and coiled-coil centrosomal protein 1
chr5_-_31474372 1.01 ENSDART00000162577
actin related protein 2/3 complex, subunit 5-like, b
chr11_-_25019298 1.01 ENSDART00000130477
ENSDART00000079578
snail family zinc finger 1a
chr8_+_26015350 1.00 ENSDART00000004521
ariadne homolog 2 (Drosophila)
chr23_+_35551931 1.00 ENSDART00000132609
cyclin T1
chr15_-_28654137 1.00 ENSDART00000156049
slingshot protein phosphatase 2a
chr20_+_26005068 0.99 ENSDART00000016864
solute carrier family 35, member F6
chr18_+_38963423 0.99

chr12_+_18794467 0.99 ENSDART00000127536
chromobox homolog 7b
chr23_+_38313746 0.99 ENSDART00000129593
zinc finger protein 217
chr19_+_10477101 0.98 ENSDART00000151735
NECAP endocytosis associated 1
chr23_+_39718769 0.98 ENSDART00000034690
OTU deubiquitinase 3
chr23_+_22052173 0.98 ENSDART00000087110
eukaryotic translation initiation factor 4 gamma, 3b
chr17_+_43916865 0.98 ENSDART00000049503
pellino E3 ubiquitin protein ligase family member 2
chr17_-_9806413 0.98 ENSDART00000021942
e2f-associated phosphoprotein
chr13_-_33096839 0.97 ENSDART00000057386
golgin A5
chr22_+_23260413 0.97

chr24_+_14095601 0.97 ENSDART00000124740
nuclear receptor coactivator 2
chr20_-_21906340 0.97 ENSDART00000145807
si:ch211-207i1.2
chr5_-_18393705 0.94 ENSDART00000010101
ENSDART00000099434
acetoacetyl-CoA synthetase
chr3_-_15529108 0.92 ENSDART00000080441
zgc:66443
chr2_-_45118469 0.92 ENSDART00000018818
mitochondrial E3 ubiquitin protein ligase 1a
chr23_+_32015527 0.92 ENSDART00000088607
nuclear envelope integral membrane protein 1
chr15_-_37687790 0.92 ENSDART00000154641
proline and serine rich 3
chr8_-_25696708 0.91 ENSDART00000007482
testis specific protein, Y-linked
chr3_+_19536018 0.90 ENSDART00000006490
tousled-like kinase 2
chr19_-_33013672 0.90 ENSDART00000134149
zgc:91944
chr3_+_52745606 0.88 ENSDART00000104683
pre-B-cell leukemia transcription factor 4
chr13_+_28487504 0.88 ENSDART00000087001
cyclin and CBS domain divalent metal cation transport mediator 2a
chr15_+_45738963 0.88

chr22_-_28828300 0.88 ENSDART00000104880
si:dkeyp-34c12.1
chr5_-_56254422 0.87 ENSDART00000014028
protein phosphatase, Mg2+/Mn2+ dependent, 1Db
chr6_-_8009055 0.86 ENSDART00000151358
ral guanine nucleotide dissociation stimulator-like 3a
chr13_+_969851 0.86 ENSDART00000139560
protein phosphatase 3, regulatory subunit B, alpha a
chr4_+_8669695 0.83 ENSDART00000168768
adiponectin receptor 2
chr15_+_25745737 0.83 ENSDART00000077853
hypermethylated in cancer 1
chr14_+_2820269 0.82 ENSDART00000162445
HMG box domain containing 3
chr1_+_8594006 0.82 ENSDART00000142384
ENSDARG00000092791
chr12_-_28422582 0.81 ENSDART00000067762
myosin ID
chr15_+_27000663 0.81 ENSDART00000023842
protein phosphatase, Mg2+/Mn2+ dependent, 1Da
chr4_-_4247251 0.81 ENSDART00000150279
CD9 molecule b
chr19_-_10737772 0.80 ENSDART00000081379
oleoyl-ACP hydrolase
chr23_+_22052045 0.80 ENSDART00000145172
eukaryotic translation initiation factor 4 gamma, 3b
chr13_-_22772707 0.80 ENSDART00000089133
RUN and FYVE domain containing 2
chr15_-_37687938 0.79 ENSDART00000154641
proline and serine rich 3
chr21_+_34053590 0.79 ENSDART00000147519
ENSDART00000158115
ENSDART00000029599
ENSDART00000145123
myotubularin related protein 1b
chr17_+_33205888 0.79 ENSDART00000104476
sorting nexin 9a
chr23_+_44470297 0.79 ENSDART00000149842
methylphosphate capping enzyme
chr21_-_9689702 0.79 ENSDART00000158836
Rho GTPase activating protein 24
chr3_-_26060702 0.78 ENSDART00000144726
yippee-like 3
chr17_+_10592507 0.78 ENSDART00000097274
autophagy related 14
chr5_+_44538762 0.77 ENSDART00000172702
ENSDART00000136002
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr10_-_6587666 0.77 ENSDART00000158881
chromodomain helicase DNA binding protein 1
chr20_-_16949608 0.77 ENSDART00000027582
breast cancer metastasis-suppressor 1-like b
chr5_+_36904127 0.77 ENSDART00000165465
si:ch1073-224n8.1
chr7_-_24557143 0.77 ENSDART00000138193
OTU deubiquitinase, ubiquitin aldehyde binding 1b
chr13_-_22772577 0.77 ENSDART00000089133
RUN and FYVE domain containing 2
chr3_-_26060748 0.75 ENSDART00000144726
yippee-like 3
chr3_+_10182994 0.75 ENSDART00000156700
chromobox homolog 2 (Drosophila Pc class)
chr2_-_30216455 0.75 ENSDART00000130142
ubiquitin-conjugating enzyme E2W (putative)
chr7_+_72030256 0.75 ENSDART00000172021
toll interacting protein
chr2_+_33206305 0.74 ENSDART00000145588
ring finger protein 220a
chr23_-_36350288 0.74 ENSDART00000110478
zgc:174906
chr3_-_15325178 0.74 ENSDART00000139575
spinster homolog 1 (Drosophila)
chr3_+_10182687 0.74 ENSDART00000156700
chromobox homolog 2 (Drosophila Pc class)
chr3_+_54777037 0.73 ENSDART00000132587
N-methylpurine DNA glycosylase
chr17_+_43729816 0.72 ENSDART00000164097
ENSDARG00000101112
chr15_+_27000248 0.72 ENSDART00000023842
protein phosphatase, Mg2+/Mn2+ dependent, 1Da
chr19_-_25842574 0.71 ENSDART00000036854
glucocorticoid induced 1
KN149858v1_+_13014 0.71 ENSDART00000165916
mediator complex subunit 8
chr16_-_55263338 0.70 ENSDART00000113358
WD and tetratricopeptide repeats 1
chr1_+_50547341 0.70 ENSDART00000132141
BTB (POZ) domain containing 3a
chr8_+_12913443 0.70 ENSDART00000081601
choline/ethanolamine phosphotransferase 1a
chr12_+_43683149 0.69 ENSDART00000162014
si:ch211-232h12.2
chr22_+_37696341 0.68 ENSDART00000007346
proteasome 26S subunit, non-ATPase 1
chr10_-_25755035 0.67 ENSDART00000140483
SR-related CTD-associated factor 4a
chr2_-_30216703 0.67 ENSDART00000130142
ubiquitin-conjugating enzyme E2W (putative)
chr2_+_17027403 0.67 ENSDART00000164329
protein phosphatase 1, regulatory (inhibitor) subunit 7
chr10_-_39272645 0.67 ENSDART00000161758
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr8_-_25696852 0.67 ENSDART00000007482
testis specific protein, Y-linked
chr9_+_24398747 0.66 ENSDART00000090280
ENSDART00000133479
zgc:153901
chr10_+_39272734 0.66 ENSDART00000075943
etoposide induced 2.4
chr24_-_26224123 0.66 ENSDART00000080039
leucine rich repeat containing 31
chr20_+_53563189 0.66 ENSDART00000060432
cell division cycle 40 homolog (S. cerevisiae)
chr24_-_5903682 0.66 ENSDART00000007373
ENSDART00000135124
acyl-CoA binding domain containing 5a
chr10_+_573116 0.66 ENSDART00000129856
ENSDART00000110384
SMAD family member 4a
chr13_-_42274444 0.65 ENSDART00000043069
membrane-associated ring finger (C3HC4) 5
chr2_+_11422195 0.65 ENSDART00000019078
LIM homeobox 8a
chr2_-_24413154 0.64 ENSDART00000145526
solute carrier family 12 (potassium/chloride transporter), member 7a
chr14_+_8288174 0.64 ENSDART00000037749
syntaxin 5A
chr4_+_5147577 0.64 ENSDART00000067392
tp53-induced glycolysis and apoptosis regulator b
chr20_-_3258772 0.63 ENSDART00000166831
ribosomal protein S6 kinase polypeptide 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.3 GO:0006449 regulation of translational termination(GO:0006449)
0.5 1.5 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.4 2.8 GO:0070933 histone H4 deacetylation(GO:0070933)
0.4 2.8 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.4 2.2 GO:0036268 swimming(GO:0036268)
0.3 1.7 GO:0097009 energy homeostasis(GO:0097009)
0.3 0.9 GO:0032024 positive regulation of peptide secretion(GO:0002793) positive regulation of insulin secretion(GO:0032024) positive regulation of hormone secretion(GO:0046887) positive regulation of peptide hormone secretion(GO:0090277)
0.3 1.9 GO:0042989 sequestering of actin monomers(GO:0042989)
0.2 2.0 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.2 1.0 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.2 1.3 GO:0050428 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.2 1.1 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.2 0.6 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) hepatic duct development(GO:0061011)
0.2 2.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.2 3.0 GO:0090398 cellular senescence(GO:0090398)
0.2 1.4 GO:0014009 glial cell proliferation(GO:0014009) regulation of glial cell proliferation(GO:0060251)
0.2 0.7 GO:0051055 negative regulation of lipid biosynthetic process(GO:0051055)
0.2 4.7 GO:0008078 mesodermal cell migration(GO:0008078)
0.2 1.1 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.2 0.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 4.7 GO:0003171 atrioventricular valve development(GO:0003171)
0.2 1.0 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.2 0.6 GO:1900543 negative regulation of nucleotide metabolic process(GO:0045980) negative regulation of purine nucleotide metabolic process(GO:1900543)
0.2 0.8 GO:0031507 heterochromatin assembly(GO:0031507)
0.2 7.8 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.1 0.6 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.8 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 1.1 GO:0030011 maintenance of cell polarity(GO:0030011) maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.5 GO:0018008 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.1 1.5 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.8 GO:1902914 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.1 2.7 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.1 0.6 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 1.2 GO:0035794 positive regulation of mitochondrial membrane permeability(GO:0035794) mitochondrial outer membrane permeabilization(GO:0097345) positive regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902110) mitochondrial outer membrane permeabilization involved in programmed cell death(GO:1902686)
0.1 0.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 1.3 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.7 GO:0030242 pexophagy(GO:0030242)
0.1 0.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 1.2 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.1 4.7 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.1 1.1 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 0.4 GO:0035313 negative regulation of Rac protein signal transduction(GO:0035021) wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.1 4.6 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 1.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.3 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.1 0.8 GO:0007584 response to nutrient(GO:0007584)
0.1 0.4 GO:0000423 macromitophagy(GO:0000423)
0.1 2.9 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.1 4.0 GO:0016575 histone deacetylation(GO:0016575)
0.1 0.5 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 2.0 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 3.2 GO:0000281 mitotic cytokinesis(GO:0000281)
0.1 1.0 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 2.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.3 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 1.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.9 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.6 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.6 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 1.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.8 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.9 GO:0051646 mitochondrion localization(GO:0051646)
0.0 1.9 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 1.0 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 2.0 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.5 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.2 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.0 0.3 GO:0071850 positive regulation of cytokinesis(GO:0032467) mitotic cell cycle arrest(GO:0071850)
0.0 0.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.4 GO:0045471 response to ethanol(GO:0045471)
0.0 2.1 GO:0048477 oogenesis(GO:0048477)
0.0 1.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.5 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 1.9 GO:0071599 otic vesicle development(GO:0071599)
0.0 0.7 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.1 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 0.2 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.5 GO:0071910 determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
0.0 0.7 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.1 GO:0003342 bulbus arteriosus development(GO:0003232) proepicardium development(GO:0003342) septum transversum development(GO:0003343)
0.0 0.1 GO:0051972 regulation of telomerase activity(GO:0051972)
0.0 1.6 GO:0006334 nucleosome assembly(GO:0006334)
0.0 1.1 GO:0048741 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 0.4 GO:0051307 meiotic chromosome separation(GO:0051307)
0.0 0.8 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 0.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 2.1 GO:0006413 translational initiation(GO:0006413)
0.0 0.4 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.4 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.6 GO:0048821 erythrocyte development(GO:0048821)
0.0 0.6 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 1.8 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 3.0 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.8 GO:0016573 histone acetylation(GO:0016573)
0.0 0.4 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.7 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.8 GO:0048916 posterior lateral line development(GO:0048916)
0.0 0.1 GO:0007032 endosome organization(GO:0007032)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.8 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.4 2.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.3 1.4 GO:0017177 glucosidase II complex(GO:0017177)
0.3 0.8 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 2.0 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.2 1.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 0.8 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 2.8 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.3 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.1 0.6 GO:1990246 uniplex complex(GO:1990246)
0.1 0.8 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 1.0 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 0.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.5 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 6.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.0 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 1.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.1 GO:0042583 chromaffin granule(GO:0042583)
0.1 0.7 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.8 GO:0016605 PML body(GO:0016605)
0.0 1.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 2.2 GO:0005776 autophagosome(GO:0005776)
0.0 1.1 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.3 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 1.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.3 GO:0005884 actin filament(GO:0005884)
0.0 0.8 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.0 GO:0031985 Golgi cisterna(GO:0031985)
0.0 3.6 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 0.6 GO:0043596 nuclear replication fork(GO:0043596)
0.0 5.3 GO:0005730 nucleolus(GO:0005730)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 13.0 GO:0005829 cytosol(GO:0005829)
0.0 0.1 GO:0000784 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.0 0.5 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.5 GO:0031201 SNARE complex(GO:0031201)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.9 2.8 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.7 2.7 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.5 1.5 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.3 6.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.3 0.8 GO:0048270 methionine adenosyltransferase regulator activity(GO:0048270)
0.2 2.8 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 0.7 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.2 1.3 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2 1.9 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 1.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.2 1.2 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.2 1.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.2 3.2 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.2 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.2 0.6 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.2 1.9 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 0.9 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 2.0 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 1.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 0.5 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.1 1.0 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 3.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.8 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 2.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 2.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 1.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 4.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 2.3 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.1 1.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.6 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 0.7 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.1 0.7 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.4 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 1.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 1.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.9 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.0 1.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 2.1 GO:0005496 steroid binding(GO:0005496)
0.0 2.0 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 1.1 GO:0030145 manganese ion binding(GO:0030145)
0.0 5.1 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 2.0 GO:0003724 RNA helicase activity(GO:0003724)
0.0 1.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 2.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 5.4 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.8 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 2.7 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 5.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.9 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.7 GO:0015293 symporter activity(GO:0015293)
0.0 2.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 2.3 GO:0042393 histone binding(GO:0042393)
0.0 1.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.3 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.4 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 1.0 GO:0042803 protein homodimerization activity(GO:0042803)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 1.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 1.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 0.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.1 PID RAS PATHWAY Regulation of Ras family activation
0.1 0.7 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 3.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.7 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 4.8 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.2 1.7 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.2 1.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 1.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 2.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 0.7 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 1.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.0 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 1.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.5 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 0.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 0.9 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 1.9 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 2.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 0.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.4 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 1.1 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.0 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 8.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.8 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis