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DANIO-CODE
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Results for foxp3b
Z-value: 3.10
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Transcription factors associated with foxp3b
Network of associatons between targets according to the STRING database.
First level regulatory network of foxp3b
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr11_+_2527564 Show fit | 6.30 |
ENSDART00000175330
|
DnaJ (Hsp40) homolog, subfamily C, member 14 |
|
| chr15_+_38397772 Show fit | 6.29 |
ENSDART00000142403
|
si:dkey-24p1.6 |
|
| chr5_-_32636372 Show fit | 6.08 |
ENSDART00000085512
ENSDART00000144694 |
KN motif and ankyrin repeat domains 1b |
|
| chr14_-_15777250 Show fit | 6.08 |
ENSDART00000165656
|
MAX dimerization protein 3 |
|
| chr23_+_19663746 Show fit | 6.01 |
ENSDART00000170149
|
sarcolemma associated protein b |
|
| chr21_-_30256477 Show fit | 5.58 |
ENSDART00000137193
|
stem-loop binding protein 2 |
|
| chr17_-_30884905 Show fit | 5.31 |
ENSDART00000131633
ENSDART00000146824 |
Enah/Vasp-like a |
|
| chr18_+_17545564 Show fit | 4.96 |
ENSDART00000061007
|
metallothionein 2 |
|
| chr11_-_6442588 Show fit | 4.90 |
ENSDART00000137879
|
zgc:162969 |
|
| chr6_+_51713264 Show fit | 4.83 |
ENSDART00000146281
|
family with sequence similarity 65, member C |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 11.3 | GO:0006886 | intracellular protein transport(GO:0006886) |
| 0.1 | 10.9 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
| 1.7 | 10.1 | GO:0040016 | embryonic cleavage(GO:0040016) |
| 0.0 | 9.7 | GO:0016567 | protein ubiquitination(GO:0016567) |
| 0.2 | 9.6 | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029) |
| 0.8 | 8.9 | GO:0044154 | histone H3-K14 acetylation(GO:0044154) |
| 0.1 | 8.6 | GO:0070646 | protein modification by small protein removal(GO:0070646) |
| 0.1 | 8.6 | GO:0006338 | chromatin remodeling(GO:0006338) |
| 0.3 | 7.8 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
| 0.5 | 7.4 | GO:0070828 | heterochromatin organization(GO:0070828) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 28.7 | GO:0005654 | nucleoplasm(GO:0005654) |
| 0.1 | 16.1 | GO:0005730 | nucleolus(GO:0005730) |
| 0.1 | 14.8 | GO:0005815 | microtubule organizing center(GO:0005815) |
| 0.4 | 14.5 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.3 | 13.2 | GO:0016605 | PML body(GO:0016605) |
| 0.3 | 9.3 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.1 | 9.1 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.6 | 8.9 | GO:0070775 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.6 | 8.0 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.1 | 8.0 | GO:0005802 | trans-Golgi network(GO:0005802) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 13.4 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.1 | 11.6 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 0.1 | 11.1 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.1 | 10.9 | GO:0042803 | protein homodimerization activity(GO:0042803) |
| 0.1 | 10.7 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
| 0.1 | 10.0 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.1 | 9.9 | GO:0003724 | RNA helicase activity(GO:0003724) |
| 0.1 | 9.9 | GO:0036459 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.8 | 8.9 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994) |
| 0.8 | 8.9 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 18.9 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.6 | 9.8 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.9 | 6.4 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.9 | 5.7 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.6 | 5.1 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.1 | 5.0 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 3.9 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 3.3 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.5 | 3.2 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.1 | 3.1 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 28.4 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.8 | 16.2 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.4 | 13.8 | REACTOME PERK REGULATED GENE EXPRESSION | Genes involved in PERK regulated gene expression |
| 0.5 | 13.0 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.5 | 9.2 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.2 | 9.1 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.2 | 8.8 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.4 | 7.6 | REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION | Genes involved in RORA Activates Circadian Expression |
| 0.3 | 6.9 | REACTOME GROWTH HORMONE RECEPTOR SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.1 | 6.3 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |