ISMARA results: gata1a+gata2b

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Results for gata1a+gata2b

Z-value: 0.21

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Transcription factors associated with gata1a+gata2b

Gene Symbol	Gene ID	Gene Info
gata2b NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000009094	GATA binding protein 2b
gata1a NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000013477	GATA binding protein 1a

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
gata1a	dr10_dc_chr11_-_25181234_25181253	-0.65	6.1e-03	Click!

Activity profile of gata1a+gata2b motif

Sorted Z-values of gata1a+gata2b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of gata1a+gata2b

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Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr22_+_21373501 Show fit	0.47	ENSDART00000089408	shdb NCBI UniProt ZFIN ENSEMBL Google Show fit	Src homology 2 domain containing transforming protein D, b
chr6_-_49160475 Show fit	0.42	ENSDART00000041942	tspan2a NCBI UniProt ZFIN ENSEMBL Google Show fit	tetraspanin 2a
chr22_-_11817641 Show fit	0.34	ENSDART00000000192	ptpn4b NCBI UniProt ZFIN ENSEMBL Google Show fit	protein tyrosine phosphatase, non-receptor type 4b
chr17_+_23534953 Show fit	0.33	ENSDART00000135814	pank1a NCBI UniProt ZFIN ENSEMBL Google Show fit	pantothenate kinase 1a
chr5_-_6054581 Show fit	0.28
chr6_+_9735100 Show fit	0.23	ENSDART00000171518	abi2b NCBI UniProt ZFIN ENSEMBL Google Show fit	abl-interactor 2b
chr22_-_16244177 Show fit	0.22	ENSDART00000105681	cdc14ab NCBI UniProt ZFIN ENSEMBL Google Show fit	cell division cycle 14Ab
chr8_-_6782167 Show fit	0.20	ENSDART00000135834 ENSDART00000172157	dock5 NCBI UniProt ZFIN ENSEMBL Google Show fit	dedicator of cytokinesis 5
chr17_+_23534824 Show fit	0.18	ENSDART00000135814	pank1a NCBI UniProt ZFIN ENSEMBL Google Show fit	pantothenate kinase 1a
chr4_-_1496779 Show fit	0.15	ENSDART00000166360	nap1l1 NCBI UniProt ZFIN ENSEMBL Google Show fit	nucleosome assembly protein 1-like 1
chr5_+_17543117 Show fit	0.12	ENSDART00000132164	hira NCBI UniProt ZFIN ENSEMBL Google Show fit	histone cell cycle regulator a
chr19_+_12525407 Show fit	0.11	ENSDART00000135706	ldlrad4a NCBI UniProt ZFIN ENSEMBL Google Show fit	low density lipoprotein receptor class A domain containing 4a
chr25_+_32085705 Show fit	0.11	ENSDART00000132698	ctdspl2a NCBI UniProt ZFIN ENSEMBL Google Show fit	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2a
chr6_-_49160398 Show fit	0.08	ENSDART00000143241	tspan2a NCBI UniProt ZFIN ENSEMBL Google Show fit	tetraspanin 2a
chr10_+_42761028 Show fit	0.05	ENSDART00000075259	fgfr1b NCBI UniProt ZFIN ENSEMBL Google Show fit	fibroblast growth factor receptor 1b
chr20_+_34126950 Show fit	0.01	ENSDART00000134305	prg4b NCBI UniProt ZFIN ENSEMBL Google Show fit	proteoglycan 4b
chr7_+_15081529 Show fit	0.01	ENSDART00000006018	mespaa NCBI UniProt ZFIN ENSEMBL Google Show fit	mesoderm posterior aa

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.5	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.2	GO:0071850	mitotic cell cycle arrest(GO:0071850)
0.0	0.1	GO:0060394	SMAD protein complex assembly(GO:0007183) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:1902636	kinociliary basal body(GO:1902636)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0004594	pantothenate kinase activity(GO:0004594)
0.1	0.5	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0070412	R-SMAD binding(GO:0070412)