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Results for gata1b+gata2a

Z-value: 3.21

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Transcription factors associated with gata1b+gata2a

Gene Symbol Gene ID Gene Info
gata1b
ENSDARG00000059130 GATA binding protein 1b
gata2a
ENSDARG00000059327 GATA binding protein 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gata2adr10_dc_chr11_-_3846064_38461210.888.0e-06Click!

Activity profile of gata1b+gata2a motif

Sorted Z-values of gata1b+gata2a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of gata1b+gata2a

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_+_25157675 12.48 ENSDART00000136984
fabp2
fatty acid binding protein 2, intestinal
chr23_+_7445760 10.92 ENSDART00000012194
gata5
GATA binding protein 5
chr7_-_50827308 10.68 ENSDART00000121574
col4a6
collagen, type IV, alpha 6
chr20_+_15653121 10.22 ENSDART00000152702
jun
jun proto-oncogene
chr25_+_21732255 10.14 ENSDART00000027393
ckmt1
creatine kinase, mitochondrial 1
chr15_+_19902697 9.77 ENSDART00000101204
alcamb
activated leukocyte cell adhesion molecule b
chr10_+_10843384 8.78 ENSDART00000130283
ambp
alpha-1-microglobulin/bikunin precursor
chr13_+_2774422 8.54 ENSDART00000162362
wu:fj16a03
wu:fj16a03
chr1_+_29054033 8.13 ENSDART00000054066
zic2b
zic family member 2 (odd-paired homolog, Drosophila) b
chr11_-_28367271 7.21 ENSDART00000065853
dhrs3b
dehydrogenase/reductase (SDR family) member 3b
chr2_+_4366169 7.20 ENSDART00000157903
gata6
GATA binding protein 6
chr23_+_36023748 7.17

chr12_-_5628401 6.72 ENSDART00000105884
itga3b
integrin, alpha 3b
chr10_+_13251463 6.67 ENSDART00000000887
rassf6
Ras association (RalGDS/AF-6) domain family 6
chr6_+_58921655 6.57 ENSDART00000083628
ddit3
DNA-damage-inducible transcript 3
chr8_-_50299273 6.55 ENSDART00000023639
nkx2.7
NK2 transcription factor related 7
chr7_+_34018862 6.46 ENSDART00000123498
fibinb
fin bud initiation factor b
chr23_+_25782195 6.37 ENSDART00000060059
rbms2b
RNA binding motif, single stranded interacting protein 2b
chr23_-_10747605 6.23

chr8_-_40287789 6.21 ENSDART00000074125
aplnra
apelin receptor a
chr23_-_24755654 6.21 ENSDART00000104035
ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr16_-_30606364 5.92 ENSDART00000147986
lmna
lamin A
chr23_-_23474703 5.54 ENSDART00000078936
her9
hairy-related 9
chr21_-_22510751 5.49 ENSDART00000169870
myo5b
myosin VB
chr11_-_1374026 5.48 ENSDART00000172953
rpl29
ribosomal protein L29
chr25_+_18467217 5.36 ENSDART00000170841
cav1
caveolin 1
chr8_+_7740132 5.30 ENSDART00000171325
tfe3a
transcription factor binding to IGHM enhancer 3a
chr4_-_24298444 5.25 ENSDART00000077926
ENSDART00000128368
celf2
cugbp, Elav-like family member 2
chr10_-_17527124 5.22 ENSDART00000137905
nt5c2l1
5'-nucleotidase, cytosolic II, like 1
chr12_-_20228689 5.10 ENSDART00000066384
hbbe2
hemoglobin beta embryonic-2
chr25_+_7858886 4.92 ENSDART00000171904
ucmab
upper zone of growth plate and cartilage matrix associated b
chr8_-_18502159 4.78 ENSDART00000148802
ENSDART00000149081
ENSDART00000148962
nexn
nexilin (F actin binding protein)
chr22_-_36915567 4.76 ENSDART00000029588
kng1
kininogen 1
chr22_+_16509286 4.63 ENSDART00000083063
tal1
T-cell acute lymphocytic leukemia 1
chr5_+_34022151 4.63 ENSDART00000141338
enc1
ectodermal-neural cortex 1
chr20_-_22478716 4.58 ENSDART00000110967
ENSDART00000011135
kita
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a
chr19_+_4996328 4.54 ENSDART00000165082
ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr7_-_73530653 4.53 ENSDART00000166633
ENSDART00000009888
ENSDART00000171254
casq1b
calsequestrin 1b
chr13_+_22350043 4.53 ENSDART00000136863
ldb3a
LIM domain binding 3a
chr16_+_55351732 4.50 ENSDART00000109391
CABZ01052290.1
ENSDARG00000077559
chr6_-_39278328 4.40 ENSDART00000148531
arhgef25b
Rho guanine nucleotide exchange factor (GEF) 25b
chr16_+_51316772 4.39 ENSDART00000169022
hmgn2
high mobility group nucleosomal binding domain 2
chr8_+_15968469 4.39 ENSDART00000134787
elavl4
ELAV like neuron-specific RNA binding protein 4
chr3_-_56969897 4.34

chr3_+_24145201 4.30 ENSDART00000169765
pdgfbb
platelet-derived growth factor beta polypeptide b
chr3_+_28371725 4.07 ENSDART00000151081
sept12
septin 12
chr12_+_34026544 4.00 ENSDART00000153413
cyth1b
cytohesin 1b
chr8_+_23464087 3.97 ENSDART00000026316
sema3gb
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
KN149726v1_+_1094 3.97

chr18_+_27753985 3.96 ENSDART00000141835
tspan18b
tetraspanin 18b
chr11_-_28367400 3.92 ENSDART00000065853
dhrs3b
dehydrogenase/reductase (SDR family) member 3b
chr25_-_13631707 3.84 ENSDART00000169865
lcat
lecithin-cholesterol acyltransferase
chr13_-_22901327 3.82 ENSDART00000056523
hkdc1
hexokinase domain containing 1
chr1_-_16876855 3.80 ENSDART00000125125
acsl1a
acyl-CoA synthetase long-chain family member 1a
chr8_-_40425193 3.79 ENSDART00000130798
myl7
myosin, light chain 7, regulatory
chr8_+_48488009 3.76

chr19_-_6856033 3.75 ENSDART00000170952
pvrl2l
poliovirus receptor-related 2 like
chr20_+_40247918 3.70 ENSDART00000121818
trdn
triadin
chr11_-_13069266 3.68 ENSDART00000169052
elovl1b
ELOVL fatty acid elongase 1b
chr3_+_52901602 3.64 ENSDART00000114343
brd4
bromodomain containing 4
chr6_+_54231519 3.61 ENSDART00000149542
pacsin1b
protein kinase C and casein kinase substrate in neurons 1b
chr17_-_42108276 3.59 ENSDART00000110871
ENSDART00000155484
nkx2.4a
NK2 homeobox 4a
chr17_-_14663139 3.53 ENSDART00000037371
ppp1r13ba
protein phosphatase 1, regulatory subunit 13Ba
chr5_-_63487161 3.52 ENSDART00000048395
cmlc1
cardiac myosin light chain-1
chr10_-_43200499 3.45 ENSDART00000171494
ssbp2
single-stranded DNA binding protein 2
chr17_-_13072982 3.39 ENSDART00000178859
CABZ01047998.1
ENSDARG00000105945
chr11_-_1792616 3.39

chr16_-_13652342 3.39 ENSDART00000144140
BX323458.2
ENSDARG00000094614
chr9_+_33167554 3.38 ENSDART00000007630
nhlh2
nescient helix loop helix 2
chr20_+_33972327 3.33 ENSDART00000170930
rxrgb
retinoid X receptor, gamma b
chr9_+_49054601 3.30 ENSDART00000047401
abcb11a
ATP-binding cassette, sub-family B (MDR/TAP), member 11a
chr25_-_35698109 3.26 ENSDART00000134928
nfatc3b
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3b
chr11_-_37921642 3.22

chr21_-_40607549 3.19 ENSDART00000172706
pcyt1bb
phosphate cytidylyltransferase 1, choline, beta b
chr25_+_18467835 3.15 ENSDART00000172338
cav1
caveolin 1
chr16_+_13534390 3.09 ENSDART00000157396
ENSDARG00000022807
ENSDARG00000022807
chr16_+_55121654 3.08 ENSDART00000149449
pabpc1a
poly(A) binding protein, cytoplasmic 1a
chr4_+_1680973 3.07 ENSDART00000149826
ENSDART00000166437
ENSDART00000031135
ENSDART00000172300
ENSDART00000067446
slc38a4
solute carrier family 38, member 4
chr16_+_26576242 3.05 ENSDART00000039746
epb41b
erythrocyte membrane protein band 4.1b
chr24_-_11768200 3.04 ENSDART00000033621
tm9sf1
transmembrane 9 superfamily member 1
chr14_+_26247858 3.02 ENSDART00000105932
si:dkeyp-110e4.11
si:dkeyp-110e4.11
chr5_+_14703190 2.99 ENSDART00000040826
tbx1
T-box 1
chr24_-_39970858 2.99 ENSDART00000134251
slc12a7b
solute carrier family 12 (potassium/chloride transporter), member 7b
chr1_+_25662910 2.95 ENSDART00000113020
tet2
tet methylcytosine dioxygenase 2
chr6_-_43679553 2.94 ENSDART00000150128
foxp1b
forkhead box P1b
chr5_+_37996820 2.93 ENSDART00000015136
mogat3b
monoacylglycerol O-acyltransferase 3b
chr6_-_586251 2.93 ENSDART00000148867
ENSDART00000149414
ENSDART00000149248
lgals2b
lectin, galactoside-binding, soluble, 2b
chr11_+_31022048 2.93 ENSDART00000160154
si:dkey-238i5.2
si:dkey-238i5.2
chr16_-_31835463 2.91 ENSDART00000148389
chd4b
chromodomain helicase DNA binding protein 4b
chr21_-_9313788 2.83

chr8_-_3974357 2.82 ENSDART00000163754
ENSDART00000169474
mtmr3
myotubularin related protein 3
chr18_+_27753913 2.74 ENSDART00000141835
tspan18b
tetraspanin 18b
chr18_+_48433986 2.72 ENSDART00000076861
fli1a
Fli-1 proto-oncogene, ETS transcription factor a
chr8_+_6533379 2.66 ENSDART00000138135
vsig8b
V-set and immunoglobulin domain containing 8b
chr8_-_25678416 2.64 ENSDART00000143938
sema3ga
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ga
chr24_+_19374099 2.62 ENSDART00000056081
ENSDART00000027022
sulf1
sulfatase 1
chr25_-_3730472 2.60

chr17_-_26849495 2.59 ENSDART00000153590
si:dkey-221l4.10
si:dkey-221l4.10
chr16_-_13652300 2.57 ENSDART00000144140
BX323458.2
ENSDARG00000094614
chr15_-_18110169 2.46

chr2_-_52202004 2.40 ENSDART00000165350
BX908782.1
ENSDARG00000098957
chr20_+_25567046 2.37 ENSDART00000153071
pfas
phosphoribosylformylglycinamidine synthase
chr10_+_13251650 2.37 ENSDART00000136932
rassf6
Ras association (RalGDS/AF-6) domain family 6
chr23_+_36016450 2.37 ENSDART00000103035
hoxc6a
homeobox C6a
chr14_+_28126921 2.30 ENSDART00000026846
pin4
protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)
KN150171v1_+_3909 2.29 ENSDART00000171048
CABZ01071639.1
ENSDARG00000099435
chr24_+_28441089 2.27

chr8_+_48888672 2.26

chr11_-_25181234 2.25 ENSDART00000013714
gata1a
GATA binding protein 1a
chr14_-_27754549 2.23 ENSDART00000135337
zgc:64189
zgc:64189
chr24_-_25546068 2.22 ENSDART00000015391
chrnd
cholinergic receptor, nicotinic, delta (muscle)
chr10_+_10780578 2.22 ENSDART00000170147
ENSDART00000004181
slc27a4
solute carrier family 27 (fatty acid transporter), member 4
chr16_-_22860052 2.21 ENSDART00000127570
pbxip1b
pre-B-cell leukemia homeobox interacting protein 1b
chr7_-_15004167 2.21 ENSDART00000030009
ENSDARG00000023868
ENSDARG00000023868
chr8_+_29733109 2.20 ENSDART00000020621
mapk4
mitogen-activated protein kinase 4
chr25_+_18467034 2.20 ENSDART00000170841
cav1
caveolin 1
chr22_-_36915720 2.19 ENSDART00000029588
kng1
kininogen 1
chr14_+_50011198 2.19 ENSDART00000171955
CR855307.1
ENSDARG00000099628
chr21_+_39918070 2.17 ENSDART00000135235
slc47a1
solute carrier family 47 (multidrug and toxin extrusion), member 1
chr23_+_25930072 2.16 ENSDART00000124103
hnf4a
hepatocyte nuclear factor 4, alpha
chr16_+_55121164 2.16 ENSDART00000149264
pabpc1a
poly(A) binding protein, cytoplasmic 1a
chr2_+_4366568 2.14 ENSDART00000166476
gata6
GATA binding protein 6
chr2_+_38279372 2.10 ENSDART00000076478
dhrs1
dehydrogenase/reductase (SDR family) member 1
chr4_+_7499654 2.10 ENSDART00000158999
tnnt2e
troponin T2e, cardiac
chr3_-_35472632 2.09 ENSDART00000055269
gng13b
guanine nucleotide binding protein (G protein), gamma 13b
chr7_+_44106327 2.05 ENSDART00000108766
ENSDART00000111441
cdh5
cadherin 5
chr10_+_21693418 2.05 ENSDART00000160754
pcdh1g1
protocadherin 1 gamma 1
chr3_-_26073676 2.04 ENSDART00000169123
gdpd3a
glycerophosphodiester phosphodiesterase domain containing 3a
chr5_+_52198613 2.01 ENSDART00000162459
scarb2a
scavenger receptor class B, member 2a
chr12_+_34615991 1.96

chr21_-_11741819 1.96 ENSDART00000081652
rfesd
Rieske (Fe-S) domain containing
chr22_-_11596329 1.93 ENSDART00000063133
gcga
glucagon a
chr13_+_24132494 1.92 ENSDART00000135992
abcb10
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr24_-_25545773 1.91 ENSDART00000015391
chrnd
cholinergic receptor, nicotinic, delta (muscle)
chr8_+_20592039 1.90 ENSDART00000160421
nfic
nuclear factor I/C
chr22_+_21095535 1.89

chr8_-_14113377 1.88 ENSDART00000090427
si:dkey-6n6.1
si:dkey-6n6.1
chr3_-_26073923 1.87 ENSDART00000103748
gdpd3a
glycerophosphodiester phosphodiesterase domain containing 3a
chr12_+_33879261 1.80

chr10_-_36603263 1.79 ENSDART00000108484
ENSDART00000086861
nipblb
nipped-B homolog b (Drosophila)
chr11_-_35313757 1.78 ENSDART00000031441
sema3fb
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb
chr16_+_31890795 1.74 ENSDART00000159821
atn1
atrophin 1
chr22_-_17026421 1.73 ENSDART00000138382
nfia
nuclear factor I/A
chr7_+_9659464 1.72 ENSDART00000172824
cers3a
ceramide synthase 3a
chr5_-_68024401 1.70 ENSDART00000016307
her1
hairy-related 1
chr2_+_4366515 1.66 ENSDART00000166476
gata6
GATA binding protein 6
chr16_-_24753560 1.65 ENSDART00000063083
pon3.2
paraoxonase 3, tandem duplicate 2
chr12_-_13042845 1.64 ENSDART00000152510
ccser2b
coiled-coil serine-rich protein 2b
chr1_+_25974174 1.63 ENSDART00000152144
si:dkey-25o16.2
si:dkey-25o16.2
chr3_-_12087518 1.63 ENSDART00000081374
cfap70
cilia and flagella associated protein 70
chr7_+_26980284 1.54 ENSDART00000173962
sox6
SRY (sex determining region Y)-box 6
chr13_+_45339261 1.52 ENSDART00000045329
mgst3b
microsomal glutathione S-transferase 3b
chr5_+_26127909 1.52 ENSDART00000098545
tmem150aa
transmembrane protein 150Aa
chr22_-_17026124 1.51 ENSDART00000138382
nfia
nuclear factor I/A
chr1_+_11485480 1.45 ENSDART00000132560
stra6l
STRA6-like
chr18_-_16806665 1.44 ENSDART00000048722
ampd3b
adenosine monophosphate deaminase 3b
chr11_+_43136945 1.43

chr25_-_21697789 1.41

chr5_-_12025080 1.40 ENSDART00000164190
ksr2
kinase suppressor of ras 2
chr2_-_30787161 1.33 ENSDART00000131230
rgs20
regulator of G protein signaling 20
chr8_+_22559432 1.32

chr5_+_36295353 1.31 ENSDART00000135776
srsf7a
serine/arginine-rich splicing factor 7a
chr8_-_43568078 1.29 ENSDART00000051139
ENSDART00000160289
ncor2
nuclear receptor corepressor 2
chr14_-_32063302 1.29 ENSDART00000173114
fgf13a
fibroblast growth factor 13a
chr1_+_25974337 1.28 ENSDART00000152617
si:dkey-25o16.2
si:dkey-25o16.2
chr20_+_19093073 1.27 ENSDART00000147105
tdh
L-threonine dehydrogenase
chr14_-_31918174 1.22 ENSDART00000052949
fgf13a
fibroblast growth factor 13a
chr10_+_19568414 1.21 ENSDART00000162912
vsig8a
V-set and immunoglobulin domain containing 8a
chr23_-_17524325 1.18 ENSDART00000104680
tpd52l2b
tumor protein D52-like 2b
chr10_-_175160 1.17

chr1_-_23659549 1.14 ENSDART00000177989
lrba
LPS-responsive vesicle trafficking, beach and anchor containing
chr25_+_12542563 1.13

chr8_+_15968636 1.12 ENSDART00000141173
elavl4
ELAV like neuron-specific RNA binding protein 4
chr18_+_48434068 1.12 ENSDART00000076861
fli1a
Fli-1 proto-oncogene, ETS transcription factor a
chr10_-_22988906 1.11

chr20_+_40248154 1.11 ENSDART00000121818
trdn
triadin
chr1_+_25974264 1.09 ENSDART00000152785
si:dkey-25o16.2
si:dkey-25o16.2
chr5_-_13145749 1.01 ENSDART00000166957
purba
purine-rich element binding protein Ba
chr22_-_22696091 1.00

chr2_+_38279454 0.98 ENSDART00000076478
dhrs1
dehydrogenase/reductase (SDR family) member 1
chr19_-_46058123 0.91

chr16_+_14820248 0.90

chr21_-_25719352 0.90 ENSDART00000002341
cldnc
claudin c
chr3_-_29932835 0.90

chr24_+_35173816 0.89

chr24_-_17089437 0.88

chr19_+_38270817 0.86

chr22_-_36915689 0.84 ENSDART00000029588
kng1
kininogen 1
chr15_-_19162052 0.82

chr8_-_25678085 0.81 ENSDART00000143938
sema3ga
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ga
chr13_+_24132236 0.81 ENSDART00000088005
abcb10
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr6_-_58921392 0.79

chr19_+_39100820 0.76

chr13_-_25643419 0.69 ENSDART00000145640
pdlim1
PDZ and LIM domain 1 (elfin)
chr16_+_31890895 0.69 ENSDART00000159821
atn1
atrophin 1
chr18_+_27753844 0.67 ENSDART00000141835
tspan18b
tetraspanin 18b
chr15_+_31956131 0.67

chr5_-_24247047 0.66

chr25_-_22955066 0.60 ENSDART00000024633
dusp8a
dual specificity phosphatase 8a
chr7_-_65012626 0.58

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 10.9 GO:0048618 post-embryonic morphogenesis(GO:0009886) post-embryonic foregut morphogenesis(GO:0048618)
2.7 10.7 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
2.2 6.6 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
1.8 5.5 GO:0003245 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
1.5 4.6 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
1.5 10.7 GO:0001773 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011) dendritic cell differentiation(GO:0097028)
1.5 4.5 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
1.4 9.8 GO:0021885 forebrain cell migration(GO:0021885)
1.3 10.1 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
1.3 3.8 GO:0055004 atrial cardiac myofibril assembly(GO:0055004)
1.2 4.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
1.1 7.8 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
1.1 11.1 GO:0042572 retinol metabolic process(GO:0042572)
1.1 4.3 GO:1903392 epicardial cell to mesenchymal cell transition(GO:0003347) negative regulation of adherens junction organization(GO:1903392)
1.0 8.1 GO:0033278 cell proliferation in midbrain(GO:0033278)
1.0 3.0 GO:0061323 cell proliferation involved in heart morphogenesis(GO:0061323) regulation of cell proliferation involved in heart morphogenesis(GO:2000136)
0.9 3.6 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.9 7.2 GO:0014831 gastro-intestinal system smooth muscle contraction(GO:0014831)
0.9 5.3 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.8 5.9 GO:0090342 regulation of cell aging(GO:0090342)
0.8 6.5 GO:0003207 cardiac chamber formation(GO:0003207)
0.8 4.1 GO:0051281 inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of calcium ion transport into cytosol(GO:0010524) positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) regulation of inhibitory G-protein coupled receptor phosphorylation(GO:1904323) positive regulation of inhibitory G-protein coupled receptor phosphorylation(GO:1904325)
0.8 9.0 GO:0046686 response to cadmium ion(GO:0046686)
0.7 2.2 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.7 8.8 GO:0018298 protein-chromophore linkage(GO:0018298)
0.7 2.1 GO:0001955 blood vessel maturation(GO:0001955)
0.6 10.7 GO:0071711 basement membrane organization(GO:0071711)
0.6 3.0 GO:0006211 5-methylcytosine catabolic process(GO:0006211) 5-methylcytosine metabolic process(GO:0019857)
0.6 3.5 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.6 2.2 GO:0030224 monocyte differentiation(GO:0030224)
0.5 3.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.5 3.6 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.5 5.1 GO:0015671 oxygen transport(GO:0015671)
0.5 2.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.4 4.9 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.4 2.2 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.3 3.3 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.3 2.1 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.3 2.6 GO:0031641 regulation of myelination(GO:0031641)
0.3 1.5 GO:0042694 muscle cell fate specification(GO:0042694)
0.3 1.3 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.3 3.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.2 7.5 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.2 2.0 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 1.4 GO:0071939 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.2 2.8 GO:0006884 cell volume homeostasis(GO:0006884)
0.2 4.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 5.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 3.3 GO:0032526 response to retinoic acid(GO:0032526)
0.2 2.4 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.2 2.2 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.2 9.2 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.2 1.4 GO:0006188 IMP biosynthetic process(GO:0006188) IMP salvage(GO:0032264)
0.2 10.0 GO:0033334 fin morphogenesis(GO:0033334)
0.1 5.5 GO:0050768 negative regulation of neurogenesis(GO:0050768)
0.1 1.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 0.5 GO:0006958 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.1 12.5 GO:0033993 response to lipid(GO:0033993)
0.1 2.9 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.1 0.4 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 3.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.6 GO:0034405 response to fluid shear stress(GO:0034405)
0.1 1.7 GO:0001757 somite specification(GO:0001757)
0.1 3.6 GO:0021854 hypothalamus development(GO:0021854)
0.1 1.2 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 1.2 GO:0030225 macrophage differentiation(GO:0030225)
0.1 7.4 GO:0045765 regulation of angiogenesis(GO:0045765)
0.1 2.1 GO:0006937 regulation of muscle contraction(GO:0006937)
0.1 4.2 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.1 5.5 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 2.6 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 4.5 GO:0001756 somitogenesis(GO:0001756)
0.0 5.0 GO:0034101 erythrocyte differentiation(GO:0030218) erythrocyte homeostasis(GO:0034101)
0.0 0.9 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 2.9 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 1.7 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 5.2 GO:0006417 regulation of translation(GO:0006417)
0.0 3.2 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 5.2 GO:0006260 DNA replication(GO:0006260)
0.0 1.9 GO:0042594 response to starvation(GO:0042594)
0.0 0.2 GO:0014823 response to activity(GO:0014823)
0.0 4.2 GO:0050877 neurological system process(GO:0050877)
0.0 9.0 GO:0042981 regulation of apoptotic process(GO:0042981)
0.0 6.8 GO:0008380 RNA splicing(GO:0008380)
0.0 2.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 2.9 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 1.0 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 2.3 GO:0006364 rRNA processing(GO:0006364)
0.0 0.4 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 10.7 GO:0098644 complex of collagen trimers(GO:0098644)
0.9 4.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.9 2.6 GO:0033270 paranode region of axon(GO:0033270)
0.7 5.1 GO:0005833 hemoglobin complex(GO:0005833) haptoglobin-hemoglobin complex(GO:0031838)
0.5 4.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.3 11.1 GO:0005811 lipid particle(GO:0005811)
0.3 10.7 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.2 4.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 6.7 GO:0008305 integrin complex(GO:0008305)
0.2 8.0 GO:0030426 growth cone(GO:0030426)
0.2 4.1 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.2 5.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 5.2 GO:0031941 filamentous actin(GO:0031941)
0.1 0.6 GO:0070724 BMP receptor complex(GO:0070724)
0.1 5.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.1 4.0 GO:0016459 myosin complex(GO:0016459)
0.1 2.1 GO:0016342 catenin complex(GO:0016342)
0.1 14.5 GO:0030424 axon(GO:0030424)
0.1 2.1 GO:0005861 troponin complex(GO:0005861)
0.1 9.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 2.2 GO:0005902 microvillus(GO:0005902)
0.1 1.9 GO:0031012 extracellular matrix(GO:0031012)
0.1 14.0 GO:0005667 transcription factor complex(GO:0005667)
0.1 5.9 GO:0005882 intermediate filament(GO:0005882)
0.1 52.4 GO:0005576 extracellular region(GO:0005576)
0.0 3.6 GO:0000793 condensed chromosome(GO:0000793)
0.0 20.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 4.0 GO:0005912 adherens junction(GO:0005912)
0.0 3.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 3.6 GO:0043005 neuron projection(GO:0043005)
0.0 3.1 GO:0005938 cell cortex(GO:0005938)
0.0 3.5 GO:0005764 lysosome(GO:0005764)
0.0 2.3 GO:0005819 spindle(GO:0005819)
0.0 4.4 GO:0000785 chromatin(GO:0000785)
0.0 1.3 GO:0016607 nuclear speck(GO:0016607)
0.0 10.5 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 8.2 GO:1990904 ribonucleoprotein complex(GO:1990904)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 11.1 GO:0004745 retinol dehydrogenase activity(GO:0004745)
1.3 10.1 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
1.1 12.5 GO:0005504 fatty acid binding(GO:0005504)
1.1 11.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.8 3.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.8 3.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.7 2.9 GO:0016936 galactoside binding(GO:0016936)
0.7 5.1 GO:0031720 haptoglobin binding(GO:0031720)
0.7 4.1 GO:0060182 apelin receptor activity(GO:0060182)
0.7 3.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.7 5.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.6 3.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.5 4.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.5 2.6 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.5 6.6 GO:0008420 CTD phosphatase activity(GO:0008420)
0.4 7.2 GO:0002039 p53 binding(GO:0002039)
0.4 19.7 GO:0008013 beta-catenin binding(GO:0008013)
0.4 1.3 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.4 4.1 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.4 1.7 GO:0004064 arylesterase activity(GO:0004064)
0.4 3.8 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.4 2.9 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.4 2.2 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.3 2.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3 3.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.3 5.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.3 1.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3 4.8 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.3 2.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3 2.1 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.3 2.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 2.8 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.3 1.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 5.2 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.2 2.4 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.2 2.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 7.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 9.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 10.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 8.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 2.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 3.7 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 4.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.9 GO:0005518 collagen binding(GO:0005518)
0.1 4.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 1.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 1.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 2.0 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 1.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 2.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 12.3 GO:0008134 transcription factor binding(GO:0008134)
0.1 12.2 GO:0042802 identical protein binding(GO:0042802)
0.1 4.6 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 5.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 17.1 GO:0046983 protein dimerization activity(GO:0046983)
0.1 2.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 3.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.6 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 3.1 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 1.9 GO:0005179 hormone activity(GO:0005179)
0.0 2.1 GO:0045296 cadherin binding(GO:0045296)
0.0 36.4 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 5.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 3.1 GO:0060090 binding, bridging(GO:0060090)
0.0 4.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 1.9 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 1.0 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 9.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.9 7.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.6 10.7 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.5 10.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.5 6.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.3 11.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.2 2.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.2 6.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.2 5.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.2 5.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 3.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 11.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.3 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 10.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
1.1 9.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
1.0 7.8 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.7 6.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.6 4.1 REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.5 3.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 10.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.3 4.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.3 5.9 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.3 2.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.3 5.5 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.3 21.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.2 3.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 6.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 1.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 2.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 5.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat