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Results for gata5

Z-value: 0.51

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Transcription factors associated with gata5

Gene Symbol Gene ID Gene Info
gata5
ENSDARG00000017821 GATA binding protein 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gata5dr10_dc_chr23_+_7445760_74458830.611.2e-02Click!

Activity profile of gata5 motif

Sorted Z-values of gata5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of gata5

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_+_12613413 1.14 ENSDART00000166071
cyp2k16
cytochrome P450, family 2, subfamily K, polypeptide16
chr3_+_31490043 1.05 ENSDART00000076636
fzd2
frizzled class receptor 2
chr16_+_24069711 1.05 ENSDART00000142869
apoc2
apolipoprotein C-II
chr15_-_18425091 1.00 ENSDART00000155866
zbtb16b
zinc finger and BTB domain containing 16b
chr16_+_53238110 0.92 ENSDART00000102170
CABZ01053976.1
ENSDARG00000069929
chr18_+_24932972 0.80 ENSDART00000008638
rgma
repulsive guidance molecule family member a
chr2_+_27739201 0.78 ENSDART00000145909
sepp1b
selenoprotein P, plasma, 1b
chr23_+_7445760 0.75 ENSDART00000012194
gata5
GATA binding protein 5
chr7_+_25649559 0.72 ENSDART00000026295
arrb2b
arrestin, beta 2b
chr6_-_8126955 0.72 ENSDART00000132412
acp5a
acid phosphatase 5a, tartrate resistant
chr6_+_43236843 0.67 ENSDART00000112474
arl6ip5a
ADP-ribosylation factor-like 6 interacting protein 5a
chr25_-_21692269 0.64

chr7_-_37350985 0.63 ENSDART00000173523
nkd1
naked cuticle homolog 1 (Drosophila)
chr23_+_38239701 0.62 ENSDART00000148188
zgc:112994
zgc:112994
chr10_-_17527124 0.61 ENSDART00000137905
nt5c2l1
5'-nucleotidase, cytosolic II, like 1
chr7_+_24770873 0.61 ENSDART00000165314
AL954715.1
ENSDARG00000103682
chr23_-_26150495 0.59 ENSDART00000126299
gdi1
GDP dissociation inhibitor 1
chr25_-_13631707 0.59 ENSDART00000169865
lcat
lecithin-cholesterol acyltransferase
chr3_-_39287733 0.59

chr21_-_30074456 0.56 ENSDART00000014223
slc23a1
solute carrier family 23 (ascorbic acid transporter), member 1
chr23_+_21610798 0.55 ENSDART00000111966
arhgef10lb
Rho guanine nucleotide exchange factor (GEF) 10-like b
chr5_+_27897765 0.52 ENSDART00000166737
ENSDART00000164418
nfr
notochord formation related
chr16_-_17439735 0.51 ENSDART00000144392
zyx
zyxin
chr21_-_40811269 0.50 ENSDART00000148513
limk1b
LIM domain kinase 1b
chr11_+_27970922 0.47 ENSDART00000169360
ENSDART00000043756
ephb2b
eph receptor B2b
chr23_+_19018062 0.47 ENSDART00000104487
cox4i2
cytochrome c oxidase subunit IV isoform 2
chr22_+_1568413 0.46 ENSDART00000175704
si:ch211-255f4.11
si:ch211-255f4.11
chr3_+_32360862 0.44 ENSDART00000151329
trpm4a
transient receptor potential cation channel, subfamily M, member 4a
KN150178v1_-_23644 0.43 ENSDART00000165583
soul3
heme-binding protein soul3
chr9_+_32267615 0.42

chr4_+_13453879 0.42 ENSDART00000145069
dyrk2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr7_+_39139117 0.40 ENSDART00000165594
CT030188.1
ENSDARG00000099385
chr7_+_25793777 0.40 ENSDART00000174010
ENSDART00000173815
CT027989.1
ENSDARG00000105638
chr2_+_27739142 0.39 ENSDART00000115071
sepp1b
selenoprotein P, plasma, 1b
chr20_-_47932043 0.38 ENSDART00000085624
ipo13
importin 13
chr13_+_51154848 0.37 ENSDART00000163847
nkx6.2
NK6 homeobox 2
chr12_-_36138709 0.36 ENSDART00000130985
st6galnac
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase
chr15_-_11257445 0.36

chr7_+_39139248 0.35 ENSDART00000165594
CT030188.1
ENSDARG00000099385
chr2_+_4534596 0.33 ENSDART00000157744
ENSDART00000163111
ENSDART00000163986
wacb
WW domain containing adaptor with coiled-coil b
chr17_-_44133970 0.33 ENSDART00000126097
otx2
orthodenticle homeobox 2
chr6_-_37765778 0.32 ENSDART00000149068
nipa2
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr7_+_25794014 0.32 ENSDART00000174010
ENSDART00000173815
CT027989.1
ENSDARG00000105638
chr19_-_41933808 0.32 ENSDART00000062080
chrac1
chromatin accessibility complex 1
chr18_+_25016753 0.31 ENSDART00000099476
fam174b
family with sequence similarity 174, member B
chr23_-_1008307 0.30 ENSDART00000110588
cdh26.1
cadherin 26, tandem duplicate 1
chr22_-_21151096 0.30 ENSDART00000131743
si:ch211-87h14.3
si:ch211-87h14.3
chr10_-_24422496 0.29 ENSDART00000141332
ENSDART00000100772
slc43a2b
solute carrier family 43 (amino acid system L transporter), member 2b
chr19_-_11096996 0.27 ENSDART00000010997
tpm3
tropomyosin 3
chr11_+_11809234 0.27 ENSDART00000168346
CR848705.1
ENSDARG00000102054
chr8_-_31597252 0.26 ENSDART00000018886
ghra
growth hormone receptor a
chr15_+_25700036 0.26 ENSDART00000135409
ENSDART00000162240
tsr1
TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
chr11_+_38858351 0.25 ENSDART00000155746
cdc42
cell division cycle 42
chr9_+_32267297 0.24

chr2_-_53797503 0.23 ENSDART00000057053
im:7138239
im:7138239
chr9_-_6683651 0.23 ENSDART00000061593
pou3f3a
POU class 3 homeobox 3a
chr4_+_22749707 0.22

chr6_-_54103765 0.21 ENSDART00000083880
hyal2a
hyaluronoglucosaminidase 2a
chr6_+_19167652 0.21 ENSDART00000086619
prkca
protein kinase C, alpha
chr2_-_53248164 0.19 ENSDART00000114682
ralbp1
ralA binding protein 1
chr5_+_18421698 0.19 ENSDART00000051621
pgam5
PGAM family member 5, serine/threonine protein phosphatase, mitochondrial
chr9_+_50670635 0.18 ENSDART00000179475
CABZ01083707.1
ENSDARG00000107278
chr10_+_42761097 0.18 ENSDART00000075259
fgfr1b
fibroblast growth factor receptor 1b
chr2_-_53797678 0.17 ENSDART00000057053
im:7138239
im:7138239
chr3_-_7252474 0.16

chr19_-_4769990 0.16

chr19_+_341775 0.15 ENSDART00000151013
ensaa
endosulfine alpha a
chr6_+_24561921 0.15 ENSDART00000169283
znf644b
zinc finger protein 644b
chr17_-_17744885 0.14 ENSDART00000155261
slirp
SRA stem-loop interacting RNA binding protein
chr8_-_25678416 0.13 ENSDART00000143938
sema3ga
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ga
chr16_+_12922721 0.13 ENSDART00000008535
u2af2a
U2 small nuclear RNA auxiliary factor 2a
chr16_-_30463239 0.12 ENSDART00000003752
cct3
chaperonin containing TCP1, subunit 3 (gamma)
chr3_-_14545180 0.12 ENSDART00000133850
gadd45gip1
growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr6_+_43236957 0.11 ENSDART00000112474
arl6ip5a
ADP-ribosylation factor-like 6 interacting protein 5a
chr15_+_22078226 0.11 ENSDART00000079504
ankk1
ankyrin repeat and kinase domain containing 1
chr7_+_34394526 0.10

chr13_-_4005533 0.10 ENSDART00000132354
tjap1
tight junction associated protein 1 (peripheral)
chr3_-_13771322 0.10 ENSDART00000159177
ENSDART00000165174
si:dkey-61n16.5
si:dkey-61n16.5
chr8_+_8934762 0.10 ENSDART00000133137
bcap31
B-cell receptor-associated protein 31
chr3_+_33309011 0.09 ENSDART00000164322
gtpbp1
GTP binding protein 1
chr6_-_54103833 0.09 ENSDART00000083880
hyal2a
hyaluronoglucosaminidase 2a
chr11_+_5845373 0.09 ENSDART00000111374
ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7, (NADH-coenzyme Q reductase)
chr1_+_45147775 0.09 ENSDART00000179047
map2k7
mitogen-activated protein kinase kinase 7
chr4_+_13453833 0.09 ENSDART00000145069
dyrk2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr20_+_23602537 0.08

chr19_-_11096542 0.08

chr16_+_24818799 0.08 ENSDART00000155217
si:dkey-79d12.4
si:dkey-79d12.4
chr19_-_7913229 0.06 ENSDART00000104703
znf687b
zinc finger protein 687b
chr4_-_5904787 0.06 ENSDART00000169439
arl1
ADP-ribosylation factor-like 1
chr20_-_35173500 0.06 ENSDART00000019196
lft1
lefty1
chr8_+_6533379 0.06 ENSDART00000138135
vsig8b
V-set and immunoglobulin domain containing 8b
chr24_-_7602759 0.06 ENSDART00000041714
atp6v0a1b
ATPase, H+ transporting, lysosomal V0 subunit a1b
chr22_+_35090105 0.05

chr1_+_58365570 0.05 ENSDART00000152669
gpr108
G protein-coupled receptor 108
chr20_-_10500595 0.05 ENSDART00000064112
glrx5
glutaredoxin 5 homolog (S. cerevisiae)
chr7_-_68989537 0.05 ENSDART00000176894
phlpp2
PH domain and leucine rich repeat protein phosphatase 2
chr6_-_16267366 0.04 ENSDART00000089445
agap1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr14_+_6655541 0.04 ENSDART00000148447
hnrnpaba
heterogeneous nuclear ribonucleoprotein A/Ba
chr16_-_28333633 0.04 ENSDART00000121671
si:dkey-12j5.1
si:dkey-12j5.1
chr3_-_40791035 0.04 ENSDART00000055201
foxk1
forkhead box K1
chr22_-_22696091 0.04

chr23_-_19055201 0.03 ENSDART00000147617
bcl2l1
bcl2-like 1
chr8_-_25678085 0.03 ENSDART00000143938
sema3ga
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ga
chr11_+_14373731 0.02 ENSDART00000161879
BX571942.1
ENSDARG00000099220
chr10_+_21699252 0.02 ENSDART00000160464
pcdh1gb2
protocadherin 1 gamma b 2
chr23_+_29431388 0.02 ENSDART00000027255
tardbpl
TAR DNA binding protein, like
chr10_+_11439845 0.02 ENSDART00000064210
cwc27
CWC27 spliceosome-associated protein homolog (S. cerevisiae)
chr19_+_40792612 0.02 ENSDART00000017917
vps50
VPS50 EARP/GARPII complex subunit
chr5_+_17543117 0.01 ENSDART00000132164
hira
histone cell cycle regulator a
chr12_-_16035939 0.01 ENSDART00000090881
si:dkey-100n10.2
si:dkey-100n10.2
chr18_-_20880226 0.00 ENSDART00000090079
synm
synemin, intermediate filament protein

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.2 1.0 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.2 0.7 GO:0002031 G-protein coupled receptor internalization(GO:0002031) regulation of protein binding(GO:0043393)
0.2 0.7 GO:0048618 post-embryonic morphogenesis(GO:0009886) post-embryonic foregut morphogenesis(GO:0048618)
0.2 0.6 GO:1903533 regulation of protein targeting(GO:1903533)
0.1 0.4 GO:0002706 regulation of lymphocyte mediated immunity(GO:0002706)
0.1 0.6 GO:0015882 L-ascorbic acid transport(GO:0015882)
0.1 0.7 GO:0045453 bone resorption(GO:0045453)
0.1 1.1 GO:0007223 Wnt signaling pathway involved in heart development(GO:0003306) Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.1 1.1 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 1.0 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.1 GO:0009404 toxin metabolic process(GO:0009404)
0.1 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 1.1 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.1 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.0 0.2 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.4 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.7 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.3 GO:0000479 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 0.8 GO:0051051 negative regulation of transport(GO:0051051)
0.0 0.3 GO:0060319 primitive erythrocyte differentiation(GO:0060319)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0042627 chylomicron(GO:0042627)
0.1 0.2 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 0.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.3 GO:0008623 CHRAC(GO:0008623)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 0.7 GO:0003993 acid phosphatase activity(GO:0003993) ferric iron binding(GO:0008199)
0.1 0.8 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.2 GO:0004903 growth hormone receptor activity(GO:0004903)
0.1 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 1.1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.4 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.4 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors