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Results for gata6

Z-value: 0.93

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Transcription factors associated with gata6

Gene Symbol Gene ID Gene Info
ENSDARG00000103589 GATA binding protein 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gata6dr10_dc_chr2_+_4366169_43662970.766.6e-04Click!

Activity profile of gata6 motif

Sorted Z-values of gata6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of gata6

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_+_32160464 2.74 ENSDART00000099880
wingless-type MMTV integration site family, member 11, related
chr10_+_10843384 2.73 ENSDART00000130283
alpha-1-microglobulin/bikunin precursor
chr25_+_21732255 2.53 ENSDART00000027393
creatine kinase, mitochondrial 1
chr12_-_20228689 2.44 ENSDART00000066384
hemoglobin beta embryonic-2
chr10_-_13814731 1.92 ENSDART00000145103
ciliary neurotrophic factor receptor
chr23_+_7445760 1.89 ENSDART00000012194
GATA binding protein 5
chr8_+_7740132 1.86 ENSDART00000171325
transcription factor binding to IGHM enhancer 3a
chr17_+_19479310 1.79 ENSDART00000077804
solute carrier family 22, member 15
chr13_+_2774422 1.61 ENSDART00000162362
wu:fj16a03
chr10_-_32614936 1.54 ENSDART00000143301
monoacylglycerol O-acyltransferase 2
chr5_-_63487161 1.44 ENSDART00000048395
cardiac myosin light chain-1
chr23_-_10747605 1.39

chr2_+_21342233 1.37 ENSDART00000062563
ras responsive element binding protein 1b
chr13_-_22901327 1.36 ENSDART00000056523
hexokinase domain containing 1
chr16_-_17439735 1.34 ENSDART00000144392
zyxin
chr23_+_25782195 1.30 ENSDART00000060059
RNA binding motif, single stranded interacting protein 2b
chr22_+_1568413 1.30 ENSDART00000175704
si:ch211-255f4.11
chr8_-_40287789 1.29 ENSDART00000074125
apelin receptor a
chr20_+_15653121 1.21 ENSDART00000152702
jun proto-oncogene
chr16_+_21090083 1.17 ENSDART00000052662
homeobox A13b
chr20_+_40247918 1.15 ENSDART00000121818
triadin
chr24_-_39970858 1.13 ENSDART00000134251
solute carrier family 12 (potassium/chloride transporter), member 7b
chr6_+_58921655 1.13 ENSDART00000083628
DNA-damage-inducible transcript 3
chr5_-_37521979 1.10 ENSDART00000141791
ENSDART00000170528
si:ch211-284e13.6
chr7_-_73530653 1.10 ENSDART00000166633
ENSDART00000009888
ENSDART00000171254
calsequestrin 1b
chr6_-_12079553 1.09 ENSDART00000157058
si:dkey-276j7.1
chr20_+_6600184 1.05 ENSDART00000136567
tensin 3, tandem duplicate 2
chr8_+_23464087 1.05 ENSDART00000026316
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
chr16_+_13534390 1.04 ENSDART00000157396
ENSDARG00000022807
chr1_+_1657493 1.01 ENSDART00000103850
ATPase, Na+/K+ transporting, alpha 1a polypeptide, tandem duplicate 3
chr8_-_18502159 0.98 ENSDART00000148802
ENSDART00000149081
ENSDART00000148962
nexilin (F actin binding protein)
chr5_+_49103778 0.98 ENSDART00000155405
ENSDARG00000098045
chr19_-_27730419 0.98 ENSDART00000151047
SH3-binding domain protein 5-like, b
chr19_+_4996328 0.97 ENSDART00000165082
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr14_+_33382973 0.95 ENSDART00000132488
apelin
chr3_+_52901602 0.94 ENSDART00000114343
bromodomain containing 4
chr5_+_34022151 0.94 ENSDART00000141338
ectodermal-neural cortex 1
chr17_-_13072982 0.92 ENSDART00000178859
ENSDARG00000105945
chr3_-_56969897 0.91

chr20_+_6600246 0.90 ENSDART00000136567
tensin 3, tandem duplicate 2
chr13_+_24132494 0.90 ENSDART00000135992
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr20_+_23339698 0.87 ENSDART00000074167
OCIA domain containing 2
chr23_-_30114528 0.86 ENSDART00000131209
coiled-coil domain containing 187
chr6_-_37765778 0.80 ENSDART00000149068
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr8_-_17580655 0.77

chr6_-_54103765 0.75 ENSDART00000083880
hyaluronoglucosaminidase 2a
chr25_+_18467034 0.75 ENSDART00000170841
caveolin 1
chr16_+_26576242 0.74 ENSDART00000039746
erythrocyte membrane protein band 4.1b
chr16_-_5936637 0.73 ENSDART00000085678
trafficking protein, kinesin binding 1
chr22_-_22696091 0.70

chr11_-_1374026 0.69 ENSDART00000172953
ribosomal protein L29
chr3_-_26073676 0.69 ENSDART00000169123
glycerophosphodiester phosphodiesterase domain containing 3a
chr14_-_33704021 0.68 ENSDART00000149396
ENSDART00000123607
cytoplasmic FMR1 interacting protein 2
chr23_-_23474703 0.65 ENSDART00000078936
hairy-related 9
chr12_-_26339002 0.65 ENSDART00000153214
synaptopodin 2-like b
chr11_-_9479592 0.65 ENSDART00000175829
ENSDARG00000086489
chr10_-_13814679 0.64 ENSDART00000145103
ciliary neurotrophic factor receptor
chr25_-_35698109 0.63 ENSDART00000134928
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3b
chr21_+_25899113 0.62 ENSDART00000141149
calneuron 2
chr11_-_27253835 0.61 ENSDART00000065889
wingless-type MMTV integration site family, member 7Aa
chr17_-_24666272 0.61 ENSDART00000105457
MORN repeat containing 2
chr8_-_6833841 0.60 ENSDART00000005321
neurofilament, light polypeptide b
KN150171v1_+_3909 0.59 ENSDART00000171048
ENSDARG00000099435
chr23_+_25930072 0.59 ENSDART00000124103
hepatocyte nuclear factor 4, alpha
chr16_-_22860052 0.58 ENSDART00000127570
pre-B-cell leukemia homeobox interacting protein 1b
chr3_-_26073923 0.58 ENSDART00000103748
glycerophosphodiester phosphodiesterase domain containing 3a
chr14_+_33382672 0.56 ENSDART00000075312
apelin
chr8_+_6533379 0.56 ENSDART00000138135
V-set and immunoglobulin domain containing 8b
chr16_-_13652300 0.52 ENSDART00000144140
ENSDARG00000094614
chr3_-_30810423 0.52 ENSDART00000076830
coronin, actin binding protein, 1A
chr12_+_33879261 0.51

chr11_-_35313757 0.51 ENSDART00000031441
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb
chr14_-_31918174 0.50 ENSDART00000052949
fibroblast growth factor 13a
chr14_-_47909935 0.49 ENSDART00000058789
quinoid dihydropteridine reductase a
chr3_+_20007257 0.48 ENSDART00000125281
nerve growth factor receptor a (TNFR superfamily, member 16)
chr21_-_25719352 0.47 ENSDART00000002341
claudin c
chr11_-_9479689 0.42 ENSDART00000175829
ENSDARG00000086489
chr10_-_25629613 0.42 ENSDART00000131640
T-cell lymphoma invasion and metastasis 1a
chr2_-_52202004 0.38 ENSDART00000165350
ENSDARG00000098957
chr8_+_25594106 0.37

chr19_+_38270817 0.33

chr9_-_9250896 0.30 ENSDART00000121665
cystathionine-beta-synthase b
chr13_+_24132236 0.30 ENSDART00000088005
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr3_+_28371725 0.29 ENSDART00000151081
septin 12
chr25_-_22955066 0.29 ENSDART00000024633
dual specificity phosphatase 8a
chr20_+_40248154 0.29 ENSDART00000121818
triadin
chr6_+_43236843 0.27 ENSDART00000112474
ADP-ribosylation factor-like 6 interacting protein 5a
chr15_-_19162052 0.26

chr6_-_43782889 0.25

chr15_+_31956131 0.23

chr23_+_20936600 0.23 ENSDART00000129992
paired box 7b
chr14_+_34154895 0.23 ENSDART00000147756
wingless-type MMTV integration site family, member 8a
chr7_+_26274252 0.21 ENSDART00000164824
tyrosine kinase, non-receptor, 1
chr17_-_29885237 0.20 ENSDART00000009104
estrogen-related receptor gamma a
chr4_+_16736949 0.20 ENSDART00000161394
t-complex 11, testis-specific-like 2
chr19_-_7913229 0.19 ENSDART00000104703
zinc finger protein 687b
chr17_+_27384572 0.19

chr7_-_22519196 0.18 ENSDART00000129919
ENSDARG00000091111
chr10_-_24422496 0.17 ENSDART00000141332
ENSDART00000100772
solute carrier family 43 (amino acid system L transporter), member 2b
chr20_-_16022816 0.17 ENSDART00000152828
family with sequence similarity 20, member B (H. sapiens)
chr6_-_42379717 0.16 ENSDART00000133647
ER membrane protein complex subunit 3
chr1_-_499082 0.16 ENSDART00000144406
ENSDART00000031635
excision repair cross-complementation group 5
chr21_+_39055276 0.15 ENSDART00000075958
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr6_-_54103833 0.13 ENSDART00000083880
hyaluronoglucosaminidase 2a
chr17_+_1660922 0.11 ENSDART00000159190
signal recognition particle 14
chr14_+_6655894 0.11 ENSDART00000148394
heterogeneous nuclear ribonucleoprotein A/Ba
chr17_+_8018808 0.11 ENSDART00000131200
myc target 1b
chr13_+_18235298 0.10 ENSDART00000133057
ENSDART00000111129
cell division cycle and apoptosis regulator 1
chr8_+_7740024 0.08 ENSDART00000171325
transcription factor binding to IGHM enhancer 3a
chr18_+_38928044 0.08

chr6_-_58921392 0.08

chr19_-_3208863 0.06

chr24_+_3447129 0.04 ENSDART00000134598
WD repeat domain 37
chr13_-_22901265 0.04 ENSDART00000056523
hexokinase domain containing 1
chr14_+_6656015 0.03 ENSDART00000148394
heterogeneous nuclear ribonucleoprotein A/Ba
chr8_+_7739964 0.03 ENSDART00000171325
transcription factor binding to IGHM enhancer 3a
chr1_+_58365570 0.01 ENSDART00000152669
G protein-coupled receptor 108
chr13_+_1665226 0.01 ENSDART00000029343
collagen, type XXI, alpha 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.5 1.5 GO:0042756 drinking behavior(GO:0042756)
0.5 1.9 GO:0009886 post-embryonic morphogenesis(GO:0009886) post-embryonic foregut morphogenesis(GO:0048618)
0.4 1.1 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.4 1.1 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.4 2.6 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.3 2.0 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.3 2.5 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.2 1.0 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.2 0.9 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.2 2.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 2.4 GO:0015671 oxygen transport(GO:0015671)
0.2 1.4 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.2 0.7 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.2 0.9 GO:1904323 inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of calcium ion transport into cytosol(GO:0010524) positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) regulation of inhibitory G-protein coupled receptor phosphorylation(GO:1904323) positive regulation of inhibitory G-protein coupled receptor phosphorylation(GO:1904325)
0.2 0.9 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.3 GO:0033238 regulation of cellular amino acid metabolic process(GO:0006521) regulation of cellular amine metabolic process(GO:0033238) regulation of sulfur metabolic process(GO:0042762)
0.1 0.5 GO:1902222 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1 0.6 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.0 GO:0046686 response to cadmium ion(GO:0046686)
0.1 0.7 GO:0001964 startle response(GO:0001964)
0.1 2.0 GO:0055075 potassium ion homeostasis(GO:0055075)
0.1 0.2 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.1 0.2 GO:0039015 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.1 0.6 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.6 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 1.6 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.7 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 1.3 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.2 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.7 GO:0050768 negative regulation of neurogenesis(GO:0050768)
0.0 0.6 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.0 0.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.6 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.4 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 1.2 GO:0033333 fin development(GO:0033333)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 GO:0031838 hemoglobin complex(GO:0005833) haptoglobin-hemoglobin complex(GO:0031838)
0.2 1.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.6 GO:0005883 neurofilament(GO:0005883)
0.1 1.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.7 GO:0031209 SCAR complex(GO:0031209)
0.1 0.2 GO:0097189 apoptotic body(GO:0097189)
0.0 1.6 GO:0030018 Z disc(GO:0030018)
0.0 2.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 3.2 GO:0009986 cell surface(GO:0009986)
0.0 0.1 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.7 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.3 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.5 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 GO:0031720 haptoglobin binding(GO:0031720)
0.3 2.5 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.3 0.9 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.3 1.5 GO:0031704 apelin receptor binding(GO:0031704)
0.2 0.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 0.9 GO:0060182 apelin receptor activity(GO:0060182)
0.1 1.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 1.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.6 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.5 GO:0070402 NADPH binding(GO:0070402)
0.1 0.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.0 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 1.5 GO:0016411 acylglycerol O-acyltransferase activity(GO:0016411)
0.1 2.6 GO:0019955 cytokine binding(GO:0019955)
0.1 1.0 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.1 2.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.7 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 1.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 2.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 1.0 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 0.7 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.9 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 2.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters