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Results for gcm2

Z-value: 1.06

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Transcription factors associated with gcm2

Gene Symbol Gene ID Gene Info
gcm2
ENSDARG00000045413 glial cells missing transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gcm2dr10_dc_chr24_-_8691595_86915970.533.4e-02Click!

Activity profile of gcm2 motif

Sorted Z-values of gcm2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of gcm2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr10_-_39187544 3.08 ENSDART00000148648
rps25
ribosomal protein S25
chr7_-_6219627 2.51 ENSDART00000172898
HIST2H2AB (1 of many)
zgc:165551
chr25_+_35791595 1.86 ENSDART00000103013
ENSDARG00000070286
ENSDARG00000070286
chr20_+_17840364 1.71 ENSDART00000024627
cdh2
cadherin 2, type 1, N-cadherin (neuronal)
chr16_-_20506304 1.57 ENSDART00000134980
si:dkeyp-86h10.3
si:dkeyp-86h10.3
chr16_+_25491981 1.56 ENSDART00000086333
jarid2a
jumonji, AT rich interactive domain 2a
chr5_-_15774816 1.46 ENSDART00000090684
kremen1
kringle containing transmembrane protein 1
chr1_-_20218263 1.41 ENSDART00000078271
cpe
carboxypeptidase E
chr25_+_35798656 1.40 ENSDART00000103006
zgc:110434
zgc:110434
chr25_-_35817806 1.37 ENSDART00000129969
ENSDARG00000086604
ENSDARG00000086604
chr7_-_6295302 1.33 ENSDART00000173199
HIST2H2AB (1 of many)
si:ch1073-153i20.5
chr25_+_35778740 1.31 ENSDART00000073404
zgc:114037
zgc:114037
chr25_+_34628342 1.30 ENSDART00000155501
zgc:110434
zgc:110434
chr17_-_35934175 1.28 ENSDART00000110040
ENSDART00000137525
sox11a
AL929378.1
SRY (sex determining region Y)-box 11a
ENSDARG00000092907
chr1_-_50513645 1.23 ENSDART00000047851
jag1a
jagged 1a
chr6_+_42821679 1.21 ENSDART00000046498
sema3fa
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa
chr7_-_26035308 1.21 ENSDART00000131906
zgc:77439
zgc:77439
chr25_-_34635772 1.17 ENSDART00000113870
ENSDARG00000075379
ENSDARG00000075379
chr16_+_32605735 1.16 ENSDART00000093250
pou3f2b
POU class 3 homeobox 2b
chr25_+_35787139 1.16 ENSDART00000073402
si:ch211-113a14.16
si:ch211-113a14.16
chr1_-_50513873 1.09 ENSDART00000137172
jag1a
jagged 1a
chr7_-_6295176 1.06 ENSDART00000173199
HIST2H2AB (1 of many)
si:ch1073-153i20.5
chr17_-_26592356 1.00 ENSDART00000016608
mrpl57
mitochondrial ribosomal protein L57
chr1_+_4704661 0.99 ENSDART00000040204
tuba8l2
tubulin, alpha 8 like 2
chr16_+_53178713 0.98 ENSDART00000174634
CABZ01062546.1
ENSDARG00000108858
chr7_+_1397973 0.97

chr25_-_33920256 0.95

chr16_+_12376719 0.95 ENSDART00000060037
ENSDARG00000040971
ENSDARG00000040971
chr4_+_317946 0.90 ENSDART00000132625
tulp4a
tubby like protein 4a
chr9_+_26292183 0.88

chr18_+_41243277 0.85

chr14_+_6834563 0.84 ENSDART00000170994
ENSDART00000129898
ctsf
cathepsin F
chr11_+_23522743 0.83 ENSDART00000121874
nfasca
neurofascin homolog (chicken) a
chr2_-_32521879 0.79 ENSDART00000056639
faim2a
Fas apoptotic inhibitory molecule 2a
chr20_+_27048717 0.78 ENSDART00000062066
si:dkey-177p2.6
si:dkey-177p2.6
chr23_+_1675422 0.78

chr9_-_56292487 0.78 ENSDART00000151720
si:ch211-39i22.1
si:ch211-39i22.1
chr3_-_58488929 0.74 ENSDART00000042386
unm_sa1261
un-named sa1261
chr19_+_2013850 0.73 ENSDART00000048850
sh3bp5a
SH3-domain binding protein 5a (BTK-associated)
chr6_-_37644217 0.72 ENSDART00000065119
chst7
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
chr7_+_72532825 0.72 ENSDART00000175316
FO818686.1
ENSDARG00000108531
chr18_-_21229799 0.71 ENSDART00000060160
calb2a
calbindin 2a
chr5_-_41645167 0.70

chr5_+_18421698 0.70 ENSDART00000051621
pgam5
PGAM family member 5, serine/threonine protein phosphatase, mitochondrial
chr21_+_27241416 0.68

chr9_-_3429153 0.68 ENSDART00000111386
dlx2a
distal-less homeobox 2a
chr17_-_5453357 0.67 ENSDART00000004043
enpp4
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr16_+_5778398 0.67 ENSDART00000011166
ENSDART00000126445
zgc:158689
zgc:158689
chr1_-_44239584 0.66 ENSDART00000137216
tmem176
transmembrane protein 176
chr13_-_24779651 0.63 ENSDART00000077775
kat6b
K(lysine) acetyltransferase 6B
chr1_+_1964902 0.63 ENSDART00000138396
mbnl2
muscleblind-like splicing regulator 2
chr16_+_55008251 0.60 ENSDART00000176995
CABZ01087388.1
ENSDARG00000106538
chr14_-_15393962 0.60 ENSDART00000161123
ENSDART00000167146
neurl1b
neuralized E3 ubiquitin protein ligase 1B
chr22_-_4622401 0.60 ENSDART00000106166
rx1
retinal homeobox gene 1
chr25_-_21796677 0.59 ENSDART00000089642
fbxo31
F-box protein 31
chr25_-_34639606 0.58 ENSDART00000126259
zgc:110434
zgc:110434
chr12_-_7790348 0.57 ENSDART00000148673
ank3b
ankyrin 3b
chr1_-_53746151 0.57 ENSDART00000179565
CABZ01043826.1
ENSDARG00000108130
chr1_+_33563354 0.57 ENSDART00000075584
kctd12.2
potassium channel tetramerisation domain containing 12.2
chr23_+_12799718 0.55

chr14_+_7393010 0.55 ENSDART00000123139
brd8
bromodomain containing 8
chr4_-_71770315 0.55 ENSDART00000171434
zgc:162958
zgc:162958
chr24_-_6129575 0.54 ENSDART00000021609
gad2
glutamate decarboxylase 2
chr6_+_59749159 0.54

chr17_+_51272621 0.52

chr3_+_39617522 0.52

chr7_+_73600230 0.52 ENSDART00000113375
HIST2H2AB (1 of many)
histone cluster 2 H2A family member b
chr24_-_26339981 0.51 ENSDART00000135496
eif5a
eukaryotic translation initiation factor 5A
chr7_-_73632917 0.51 ENSDART00000122392
HIST2H2AB (1 of many)
histone cluster 2 H2A family member b
chr14_-_30747259 0.51 ENSDART00000002250
hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr5_+_69490090 0.49

chr22_-_37676744 0.49 ENSDART00000028085
ttc14
tetratricopeptide repeat domain 14
chr10_+_29965951 0.49 ENSDART00000116893
SNORD14
Small nucleolar RNA SNORD14
chr5_+_37996820 0.47 ENSDART00000015136
mogat3b
monoacylglycerol O-acyltransferase 3b
chr15_+_8359658 0.46 ENSDART00000152603
egln2
egl-9 family hypoxia-inducible factor 2
chr22_-_20316908 0.46 ENSDART00000165667
tcf3b
transcription factor 3b
chr13_-_42986821 0.45 ENSDART00000164439
si:ch211-106f21.1
si:ch211-106f21.1
chr24_+_24924379 0.44 ENSDART00000115165
amer2
APC membrane recruitment protein 2
chr18_-_17410180 0.43 ENSDART00000060949
zfpm1
zinc finger protein, FOG family member 1
chr18_+_2991098 0.42 ENSDART00000165048
aamdc
adipogenesis associated, Mth938 domain containing
chr14_+_44399056 0.42 ENSDART00000173043
atp8a1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr7_-_20201358 0.41 ENSDART00000174001
ntn5
netrin 5
chr5_-_25509259 0.41 ENSDART00000137376
BX510923.1
ENSDARG00000094488
chr13_-_36420228 0.39

chr3_-_39208943 0.39

chr17_-_5453436 0.38 ENSDART00000004043
enpp4
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr19_+_32679320 0.38

chr19_+_32679258 0.38

chr17_+_13088982 0.38 ENSDART00000012670
pnn
pinin, desmosome associated protein
chr1_-_50513762 0.37 ENSDART00000047851
jag1a
jagged 1a
chr10_-_20399472 0.33 ENSDART00000080143
sfrp1b
secreted frizzled-related protein 1b
chr5_-_25509188 0.33 ENSDART00000137376
BX510923.1
ENSDARG00000094488
chr25_-_34635697 0.33 ENSDART00000113870
ENSDARG00000075379
ENSDARG00000075379
chr4_+_21319791 0.33

chr16_-_52761159 0.32 ENSDART00000111869
ubr5
ubiquitin protein ligase E3 component n-recognin 5
chr25_-_35817715 0.32 ENSDART00000129969
ENSDARG00000086604
ENSDARG00000086604
chr19_+_4093543 0.30 ENSDART00000172204
meaf6
MYST/Esa1-associated factor 6
chr3_+_32360862 0.30 ENSDART00000151329
trpm4a
transient receptor potential cation channel, subfamily M, member 4a
chr5_-_25509310 0.29 ENSDART00000137376
BX510923.1
ENSDARG00000094488
chr7_-_26035541 0.29 ENSDART00000057288
zgc:77439
zgc:77439
chr15_+_29190162 0.28 ENSDART00000105222
zgc:101731
zgc:101731
chr13_+_14873339 0.27 ENSDART00000057810
emx1
empty spiracles homeobox 1
chr14_-_16791447 0.27 ENSDART00000158002
CR812832.1
ENSDARG00000103278
chr23_+_32085181 0.27 ENSDART00000053509
plagx
pleiomorphic adenoma gene X
chr22_-_8228763 0.26 ENSDART00000097196
zmp:0000001043
zmp:0000001043
chr16_-_22260272 0.26 ENSDART00000138419
CR855277.1
ENSDARG00000092020
chr9_-_29850713 0.25 ENSDART00000156609
CU855930.2
ENSDARG00000097441
chr1_+_44239727 0.25 ENSDART00000141145
si:dkey-9i23.16
si:dkey-9i23.16
chr1_+_3674819 0.25

chr4_+_19545842 0.24 ENSDART00000140028
lrrc4.1
leucine rich repeat containing 4.1
chr20_+_23392782 0.24

chr11_+_35790782 0.22 ENSDART00000125221
CR933559.1
ENSDARG00000087939
chr2_-_24614261 0.21 ENSDART00000099532
vmhc
ventricular myosin heavy chain
chr6_-_6091628 0.21 ENSDART00000132350
rtn4a
reticulon 4a
chr20_+_43751193 0.21 ENSDART00000017269
parp1
poly (ADP-ribose) polymerase 1
chr6_+_15635696 0.21 ENSDART00000128939
iqca1
IQ motif containing with AAA domain 1
chr22_+_26840335 0.20 ENSDART00000158756
crebbpa
CREB binding protein a
chr7_-_20201693 0.20 ENSDART00000174001
ntn5
netrin 5
chr17_+_23534824 0.19 ENSDART00000135814
pank1a
pantothenate kinase 1a
chr14_-_2295383 0.18 ENSDART00000162537
ENSDART00000106705
pcdh2ab3
pcdh2ab3
protocadherin 2 alpha b 3
protocadherin 2 alpha b 3
chr3_+_32618086 0.17 ENSDART00000125260
hsd3b7
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase
chr22_-_20317201 0.17 ENSDART00000161610
tcf3b
transcription factor 3b
chr20_-_37733350 0.17

chr25_-_3730472 0.17

chr16_-_32718222 0.17 ENSDART00000161395
pnisr
PNN-interacting serine/arginine-rich protein
chr18_+_8388897 0.17 ENSDART00000083421
cpt1b
carnitine palmitoyltransferase 1B (muscle)
chr5_+_69489874 0.16

chr17_-_25545464 0.16 ENSDART00000040032
ENSDART00000163447
rtn4ip1
reticulon 4 interacting protein 1
chr7_-_4987762 0.15 ENSDART00000097877
ltb4r2a
leukotriene B4 receptor 2a
KN150118v1_+_46683 0.15

chr22_-_20317131 0.15 ENSDART00000161610
tcf3b
transcription factor 3b
chr24_+_16005004 0.14 ENSDART00000163086
ENSDART00000152087
si:dkey-118j18.2
si:dkey-118j18.2
chr6_+_42821484 0.13 ENSDART00000046498
sema3fa
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa
chr3_-_31111443 0.13 ENSDART00000076925
ITPRIPL2
ITPRIP like 2
chr11_+_38013564 0.13 ENSDART00000171496
CDK18
cyclin dependent kinase 18
chr16_+_12376861 0.12 ENSDART00000060037
ENSDARG00000040971
ENSDARG00000040971
chr13_+_30546398 0.12

chr7_-_6219521 0.12 ENSDART00000161304
HIST2H2AB (1 of many)
zgc:165551
chr7_+_5786385 0.12 ENSDART00000173404
HIST2H2AB (1 of many)
histone cluster 2 H2A family member b
chr6_+_46404650 0.11 ENSDART00000131203
ENSDART00000103472
ENSDART00000132845
ENSDART00000138567
ENSDART00000168440
pbrm1l
polybromo 1, like
chr23_-_31033917 0.10 ENSDART00000142661
osbpl2a
oxysterol binding protein-like 2a
chr6_-_60172823 0.09

chr11_+_26138359 0.09 ENSDART00000087652
cpne1
copine I
chr10_+_15078155 0.08

chr6_+_19476202 0.07 ENSDART00000113911
micall1a
MICAL-like 1a
chr6_+_15635738 0.07 ENSDART00000128939
iqca1
IQ motif containing with AAA domain 1
chr11_-_41798903 0.05 ENSDART00000162944
dnajc11b
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr7_-_73632999 0.05 ENSDART00000122392
HIST2H2AB (1 of many)
histone cluster 2 H2A family member b
chr20_-_54645903 0.04 ENSDART00000038745
yy1b
YY1 transcription factor b
chr5_-_15774729 0.04 ENSDART00000090684
kremen1
kringle containing transmembrane protein 1
chr21_-_19649065 0.04 ENSDART00000131562
ENSDART00000133467
BX927394.1
ENSDARG00000092538
chr16_+_51598269 0.03 ENSDART00000169443
SLC9A1
solute carrier family 9 member A1
chr13_-_25153833 0.02 ENSDART00000039828
ENSDART00000110304
vcla
vinculin a
chr22_-_29810429 0.02 ENSDART00000135503
BX649294.1
ENSDARG00000092881
chr7_-_18894589 0.01 ENSDART00000142924
kirrel1a
kin of IRRE like a

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0098743 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.3 1.5 GO:0048901 anterior lateral line neuromast development(GO:0048901) anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.3 1.1 GO:0050820 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.2 0.7 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.2 0.7 GO:1902869 negative regulation of photoreceptor cell differentiation(GO:0046533) regulation of amacrine cell differentiation(GO:1902869) positive regulation of amacrine cell differentiation(GO:1902871)
0.2 0.5 GO:0045905 positive regulation of translational termination(GO:0045905)
0.1 0.4 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 0.5 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.1 1.3 GO:0046548 retinal rod cell development(GO:0046548)
0.1 2.7 GO:0030878 thyroid gland development(GO:0030878)
0.1 0.6 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 0.3 GO:0002706 regulation of lymphocyte mediated immunity(GO:0002706)
0.1 0.4 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.1 0.7 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249) positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.8 GO:0019226 transmission of nerve impulse(GO:0019226)
0.1 0.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.3 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.3 GO:0035777 pronephric distal tubule development(GO:0035777)
0.1 0.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.7 GO:0061099 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.3 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.5 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.6 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 1.2 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.2 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.0 0.1 GO:0001961 positive regulation of cytokine-mediated signaling pathway(GO:0001961) positive regulation of response to cytokine stimulus(GO:0060760)
0.0 1.3 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.6 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.3 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.4 GO:0007398 ectoderm development(GO:0007398)
0.0 1.4 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.5 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.8 GO:0016358 dendrite development(GO:0016358)
0.0 0.7 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 1.6 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.2 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 1.4 GO:0016485 protein processing(GO:0016485)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 GO:0014704 intercalated disc(GO:0014704)
0.1 3.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.7 GO:0043195 terminal bouton(GO:0043195)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 0.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0016586 RSC complex(GO:0016586)
0.0 1.0 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.6 GO:0005604 basement membrane(GO:0005604)
0.0 1.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.5 GO:0005643 nuclear pore(GO:0005643)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.3 1.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 1.6 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.2 0.7 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 2.7 GO:0005112 Notch binding(GO:0005112)
0.1 0.5 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 1.3 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.5 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.6 GO:0030332 cyclin binding(GO:0030332)
0.1 0.2 GO:0004953 icosanoid receptor activity(GO:0004953)
0.0 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.5 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 1.7 GO:0045296 cadherin binding(GO:0045296)
0.0 0.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.7 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.2 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 4.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.3 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 1.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 3.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 0.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity