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Results for gfi1b

Z-value: 0.90

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Transcription factors associated with gfi1b

Gene Symbol Gene ID Gene Info
gfi1b
ENSDARG00000079947 growth factor independent 1B transcription repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gfi1bdr10_dc_chr21_-_17259886_172599330.885.9e-06Click!

Activity profile of gfi1b motif

Sorted Z-values of gfi1b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of gfi1b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr19_+_43039606 3.65 ENSDART00000010104
crtap
cartilage associated protein
chr3_-_32686790 3.13 ENSDART00000075465
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr23_-_35595271 3.13 ENSDART00000164616
tuba1c
tubulin, alpha 1c
chr17_+_15425559 2.94 ENSDART00000026180
fabp7a
fatty acid binding protein 7, brain, a
chr7_-_25623974 2.70 ENSDART00000173602
cd99l2
CD99 molecule-like 2
chr5_-_39910235 2.61 ENSDART00000146237
ENSDART00000163302
fsta
follistatin a
chr16_-_45269179 2.52 ENSDART00000162095
si:dkey-33i11.4
si:dkey-33i11.4
chr15_-_24987099 2.24

chr6_+_29800606 2.14 ENSDART00000017424
ptmaa
prothymosin, alpha a
chr2_+_32036450 2.08 ENSDART00000140776
CR391940.1
ENSDARG00000091946
chr25_-_31881585 1.89 ENSDART00000123999
ENSDART00000158091
ENSDARG00000100731
ENSDARG00000100731
chr14_+_34683602 1.83 ENSDART00000172171
ebf1a
early B-cell factor 1a
chr8_-_19364689 1.80 ENSDART00000014183
colgalt2
collagen beta(1-O)galactosyltransferase 2
chr23_+_8671759 1.73 ENSDART00000129997
rgs19
regulator of G protein signaling 19
chr19_-_28546417 1.69 ENSDART00000130922
ENSDART00000079114
irx1b
iroquois homeobox 1b
chr6_+_7309023 1.62 ENSDART00000160128
erbb3a
erb-b2 receptor tyrosine kinase 3a
chr1_+_13779755 1.59

chr1_+_12076622 1.56 ENSDART00000159226
pcdh10a
protocadherin 10a
chr12_-_3742062 1.52 ENSDART00000092983
ENSDARG00000063555
ENSDARG00000063555
chr2_-_10555152 1.51 ENSDART00000150166
gng12a
guanine nucleotide binding protein (G protein), gamma 12a
chr8_-_15144533 1.49 ENSDART00000138855
bcar3
breast cancer anti-estrogen resistance 3
chr4_-_12008472 1.48 ENSDART00000092250
btbd11a
BTB (POZ) domain containing 11a
chr9_+_48309684 1.46 ENSDART00000177287
ENSDART00000113883
ENSDARG00000041339
ENSDARG00000041339
chr23_-_10202347 1.45 ENSDART00000142442
plxnb1a
plexin b1a
chr23_+_23305483 1.40 ENSDART00000126479
plekhn1
pleckstrin homology domain containing, family N member 1
KN150342v1_-_59821 1.40 ENSDART00000163274
ENSDARG00000100757
ENSDARG00000100757
chr7_-_70219217 1.36 ENSDART00000097710
ppargc1a
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr7_+_25649559 1.35 ENSDART00000026295
arrb2b
arrestin, beta 2b
chr1_-_24988461 1.33 ENSDART00000054230
fgg
fibrinogen gamma chain
chr20_+_51034244 1.32

chr3_+_23587156 1.31

chr7_+_20699191 1.26 ENSDART00000062003
efnb3b
ephrin-B3b
chr18_+_23891068 1.25 ENSDART00000146490
BX569787.1
ENSDARG00000092402
chr10_-_39210658 1.22 ENSDART00000150193
slc37a4b
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr6_-_24003717 1.20 ENSDART00000164915
scinla
scinderin like a
chr24_-_4418454 1.19 ENSDART00000066835
fzd8a
frizzled class receptor 8a
chr10_+_9325719 1.19 ENSDART00000064968
rasgef1bb
RasGEF domain family, member 1Bb
chr6_-_12616971 1.18 ENSDART00000056764
bmpr2a
bone morphogenetic protein receptor, type II a (serine/threonine kinase)
chr20_+_19175518 1.18

chr20_-_51746555 1.16 ENSDART00000065231
disp1
dispatched homolog 1 (Drosophila)
chr21_-_17566461 1.14 ENSDART00000044078
ENSDART00000168495
ENSDART00000020048
gsna
gelsolin a
chr13_+_21649283 1.13 ENSDART00000021556
si:ch211-51a6.2
si:ch211-51a6.2
chr25_+_11317025 1.09

chr5_-_58162552 1.08 ENSDART00000161230
arhgef12b
Rho guanine nucleotide exchange factor (GEF) 12b
chr25_+_19901741 1.06 ENSDART00000026401
ENSDARG00000004577
ENSDARG00000004577
chr7_+_48047139 1.04 ENSDART00000052122
crabp1b
cellular retinoic acid binding protein 1b
chr23_-_10202175 1.04 ENSDART00000142442
plxnb1a
plexin b1a
chr14_+_34683695 1.03 ENSDART00000170631
ebf1a
early B-cell factor 1a
chr6_+_35378839 1.02 ENSDART00000102483
ENSDART00000133783
rgs4
regulator of G protein signaling 4
chr9_+_21466934 1.01 ENSDART00000139620
lats2
large tumor suppressor kinase 2
chr12_-_3741925 1.00 ENSDART00000092983
ENSDARG00000063555
ENSDARG00000063555
chr19_-_22904687 0.98 ENSDART00000141503
pleca
plectin a
chr3_-_32409303 0.98 ENSDART00000151476
rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr23_-_20494890 0.92

chr8_+_2260519 0.91 ENSDART00000136743
ikbkb
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr9_-_5618609 0.91 ENSDART00000127219
FAM155A
family with sequence similarity 155 member A
chr23_+_7537089 0.91 ENSDART00000135551
si:ch211-200e2.1
si:ch211-200e2.1
chr18_+_23891152 0.90 ENSDART00000146490
BX569787.1
ENSDARG00000092402
chr23_+_14058972 0.90 ENSDART00000090864
lmod3
leiomodin 3 (fetal)
chr2_+_10023967 0.90 ENSDART00000148227
anxa13l
annexin A13, like
chr22_-_36552513 0.90 ENSDART00000129318
CABZ01045212.1
ENSDARG00000087525
chr3_+_22246697 0.89 ENSDART00000155597
arhgap27l
Rho GTPase activating protein 27, like
chr24_+_10276926 0.89 ENSDART00000145771
ENSDART00000157350
CT573344.1
ENSDARG00000093108
chr13_-_43027245 0.88 ENSDART00000099601
ENSDARG00000068784
ENSDARG00000068784
chr9_-_1964814 0.88 ENSDART00000082354
hoxd9a
homeobox D9a
chr3_+_23561215 0.87 ENSDART00000078453
hoxb7a
homeobox B7a
chr1_-_46398498 0.87 ENSDART00000000087
itsn1
intersectin 1 (SH3 domain protein)
chr19_+_47846675 0.85 ENSDART00000041114
psmb2
proteasome subunit beta 2
chr16_+_10531986 0.85 ENSDART00000161568
ino80e
INO80 complex subunit E
chr11_+_34788205 0.85 ENSDART00000124800
fam212aa
family with sequence similarity 212, member Aa
chr16_+_10531926 0.85 ENSDART00000161568
ino80e
INO80 complex subunit E
chr14_-_29565869 0.84 ENSDART00000172349
sorbs2b
sorbin and SH3 domain containing 2b
chr21_+_38264846 0.83 ENSDART00000065159
zgc:158291
zgc:158291
chr13_+_21649237 0.83 ENSDART00000021556
si:ch211-51a6.2
si:ch211-51a6.2
chr24_+_9272045 0.82 ENSDART00000132724
si:ch211-285f17.1
si:ch211-285f17.1
chr2_+_2583068 0.82

chr7_-_26137243 0.81 ENSDART00000111494
gal3st4
galactose-3-O-sulfotransferase 4
chr21_-_33961137 0.80 ENSDART00000100508
ebf1b
early B-cell factor 1b
chr20_+_27565701 0.79

chr19_-_35642440 0.78 ENSDART00000167853
ENSDART00000054274
macf1a
microtubule-actin crosslinking factor 1a
chr2_-_32468715 0.74

chr7_+_44106327 0.74 ENSDART00000108766
ENSDART00000111441
cdh5
cadherin 5
chr19_+_2291874 0.72

chr20_+_18263793 0.72 ENSDART00000011287
aqp4
aquaporin 4
chr7_-_57727148 0.71

chr3_+_23561502 0.70 ENSDART00000078453
hoxb7a
homeobox B7a
chr9_+_34832049 0.70 ENSDART00000100735
ENSDART00000133996
shox
short stature homeobox
chr8_+_39525254 0.70

chr7_+_48047113 0.68 ENSDART00000052122
crabp1b
cellular retinoic acid binding protein 1b
chr23_+_22729939 0.68 ENSDART00000009337
eno1a
enolase 1a, (alpha)
chr6_-_16156494 0.67

chr18_-_22745846 0.64 ENSDART00000023721
nudt21
nudix hydrolase 21
chr18_+_23890892 0.64 ENSDART00000146490
BX569787.1
ENSDARG00000092402
chr3_-_12818954 0.63 ENSDART00000158747
ENSDART00000158815
pdgfab
platelet-derived growth factor alpha polypeptide b
chr17_-_12231165 0.63 ENSDART00000080927
snap25b
synaptosomal-associated protein, 25b
chr6_+_45493396 0.62 ENSDART00000159863
cntn4
contactin 4
chr25_-_14953284 0.61 ENSDART00000165632
pax6a
paired box 6a
chr14_-_9407573 0.61 ENSDART00000166739
NRK
si:zfos-2326c3.2
KN150342v1_-_60050 0.60 ENSDART00000163274
ENSDARG00000100757
ENSDARG00000100757
chr22_+_31866783 0.60 ENSDART00000159825
dock3
dedicator of cytokinesis 3
chr6_-_34237257 0.60 ENSDART00000102391
dmrt2b
doublesex and mab-3 related transcription factor 2b
chr24_+_35500964 0.59 ENSDART00000058571
snai2
snail family zinc finger 2
chr12_+_38388606 0.59 ENSDART00000081046
ttyh2
tweety family member 2
chr12_+_5969088 0.56 ENSDART00000114961
si:ch211-131k2.3
si:ch211-131k2.3
chr7_-_25624128 0.54 ENSDART00000173505
cd99l2
CD99 molecule-like 2
chr10_+_9134634 0.54 ENSDART00000110443
fstb
follistatin b
chr9_+_3048953 0.54 ENSDART00000140614
BX957292.1
ENSDARG00000092185
chr23_+_35980812 0.52

chr20_-_26142897 0.52 ENSDART00000140255
si:dkey-12h9.6
si:dkey-12h9.6
chr16_+_23367625 0.51 ENSDART00000015956
efna1b
ephrin-A1b
chr3_+_23561306 0.50 ENSDART00000078453
hoxb7a
homeobox B7a
chr3_+_29891683 0.48

chr21_-_16123432 0.46 ENSDART00000124871
ENSDART00000161979
tnfrsfa
tumor necrosis factor receptor superfamily, member a
chr12_+_27444832 0.44 ENSDART00000133719
etv4
ets variant 4
chr2_+_56705456 0.44

chr6_-_23830912 0.42

chr6_+_50393779 0.42 ENSDART00000055502
ergic3
ERGIC and golgi 3
chr5_+_69401770 0.42

chr12_-_3742020 0.41 ENSDART00000092983
ENSDARG00000063555
ENSDARG00000063555
chr25_-_3853819 0.40 ENSDART00000124749
myrf
myelin regulatory factor
chr9_+_50609926 0.38 ENSDART00000098687
GRB14
growth factor receptor bound protein 14
chr6_+_11014565 0.35 ENSDART00000132677
atg9a
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr5_+_57102973 0.32 ENSDART00000135344
ppp2r1ba
protein phosphatase 2, regulatory subunit A, beta a
chr7_+_48047266 0.32 ENSDART00000052122
crabp1b
cellular retinoic acid binding protein 1b
chr17_-_37447917 0.31 ENSDART00000075975
crip1
cysteine-rich protein 1
chr23_-_24336930 0.31 ENSDART00000160312
hspb7
heat shock protein family, member 7 (cardiovascular)
chr6_+_3356712 0.30 ENSDART00000151607
faah
fatty acid amide hydrolase
chr5_-_11593397 0.30 ENSDART00000161542
lrrc74b
leucine rich repeat containing 74B
chr3_-_30810423 0.30 ENSDART00000076830
coro1a
coronin, actin binding protein, 1A
chr7_-_27877036 0.30 ENSDART00000044208
lmo1
LIM domain only 1
chr6_+_3356617 0.30 ENSDART00000109576
faah
fatty acid amide hydrolase
chr9_+_32267297 0.29

chr8_-_25678085 0.29 ENSDART00000143938
sema3ga
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ga
chr8_-_16479344 0.27 ENSDART00000146469
ENSDART00000132681
ttc39a
tetratricopeptide repeat domain 39A
chr15_+_32863182 0.25

chr25_-_14953370 0.24 ENSDART00000159490
pax6a
paired box 6a
chr20_-_28226 0.24 ENSDART00000148717
zgc:174972
zgc:174972
chr14_-_46525518 0.21 ENSDART00000173172
si:ch211-114c17.1
si:ch211-114c17.1
chr9_+_44921233 0.20 ENSDART00000145271
nckap1
NCK-associated protein 1
chr2_+_31855153 0.19 ENSDART00000066789
stard3nl
STARD3 N-terminal like
chr19_+_20617339 0.19 ENSDART00000133633
igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr19_+_20616655 0.18 ENSDART00000163026
igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr3_-_30833046 0.18

chr10_-_34927807 0.16 ENSDART00000138755
dclk1a
doublecortin-like kinase 1a
chr25_+_17906515 0.16

KN150529v1_+_16214 0.15 ENSDART00000177459
CABZ01084538.1
ENSDARG00000108298
chr3_-_41944723 0.14 ENSDART00000083111
ttyh3a
tweety family member 3a
chr12_-_4183910 0.14 ENSDART00000129427
vkorc1
vitamin K epoxide reductase complex, subunit 1
chr21_+_27333941 0.14 ENSDART00000009234
rbm14a
RNA binding motif protein 14a
chr23_+_25930072 0.12 ENSDART00000124103
hnf4a
hepatocyte nuclear factor 4, alpha
chr9_+_19678618 0.11 ENSDART00000152034
si:ch211-140m22.7
si:ch211-140m22.7
chr23_+_8862155 0.09 ENSDART00000132992
sox18
SRY (sex determining region Y)-box 18
chr16_+_10438774 0.09 ENSDART00000121966
mdc1
mediator of DNA damage checkpoint 1
chr17_-_19809993 0.08

chr10_-_35598016 0.06 ENSDART00000162139
si:ch211-244c8.4
si:ch211-244c8.4
chr4_-_12796590 0.05 ENSDART00000075127
b2m
beta-2-microglobulin
chr25_+_17217050 0.05 ENSDART00000125459
cnot1
CCR4-NOT transcription complex, subunit 1
chr25_-_34647197 0.02 ENSDART00000114908
si:dkey-261m9.15
si:dkey-261m9.15
chr25_+_35791595 0.02 ENSDART00000103013
ENSDARG00000070286
ENSDARG00000070286
chr6_-_16156294 0.02 ENSDART00000160809
agap1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0072025 distal convoluted tubule development(GO:0072025) late distal convoluted tubule development(GO:0072068)
0.5 1.4 GO:0002031 G-protein coupled receptor internalization(GO:0002031) regulation of protein binding(GO:0043393)
0.4 3.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.4 1.2 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.4 2.5 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.3 0.8 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.3 2.0 GO:0016103 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.2 0.7 GO:0001955 blood vessel maturation(GO:0001955)
0.2 3.6 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.2 0.7 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.2 1.6 GO:0097324 melanocyte migration(GO:0097324)
0.1 0.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 1.5 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 0.9 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 1.3 GO:0070527 platelet aggregation(GO:0070527)
0.1 1.0 GO:0003139 secondary heart field specification(GO:0003139)
0.1 0.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.5 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 0.4 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.7 GO:0006833 water transport(GO:0006833)
0.1 2.3 GO:0051014 actin filament severing(GO:0051014)
0.1 0.4 GO:0043217 myelin maintenance(GO:0043217)
0.1 0.8 GO:0042694 muscle cell fate specification(GO:0042694)
0.1 0.9 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.6 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.6 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 0.3 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.1 1.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.2 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 1.0 GO:0021654 rhombomere boundary formation(GO:0021654)
0.0 0.3 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.9 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 2.0 GO:0031638 zymogen activation(GO:0031638)
0.0 1.2 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.9 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) vitamin K metabolic process(GO:0042373)
0.0 0.0 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.7 GO:0030282 bone mineralization(GO:0030282)
0.0 0.6 GO:0007548 sex differentiation(GO:0007548)
0.0 0.1 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 1.7 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.3 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.6 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.7 GO:0006821 chloride transport(GO:0006821)
0.0 1.7 GO:0030902 hindbrain development(GO:0030902)
0.0 1.3 GO:0008284 positive regulation of cell proliferation(GO:0008284)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0005577 fibrinogen complex(GO:0005577)
0.4 2.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.2 0.8 GO:0032019 mitochondrial cloud(GO:0032019)
0.2 0.9 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 0.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.6 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.5 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 1.7 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 1.0 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.9 GO:0031430 M band(GO:0031430)
0.0 0.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.9 GO:0005839 proteasome core complex(GO:0005839)
0.0 1.4 GO:0016605 PML body(GO:0016605)
0.0 0.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.7 GO:0016342 catenin complex(GO:0016342)
0.0 0.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 1.5 GO:0000786 nucleosome(GO:0000786)
0.0 0.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.8 GO:0005925 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.4 1.8 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.3 0.9 GO:0008384 IkappaB kinase activity(GO:0008384)
0.3 3.1 GO:0048185 activin binding(GO:0048185)
0.3 2.9 GO:0005504 fatty acid binding(GO:0005504)
0.2 0.8 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.2 2.0 GO:0001972 retinoic acid binding(GO:0001972)
0.2 3.6 GO:0005518 collagen binding(GO:0005518)
0.2 0.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 2.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 0.6 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.1 0.7 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.7 GO:0015250 water channel activity(GO:0015250)
0.1 1.0 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.1 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.1 2.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 3.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.6 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.4 GO:1901612 cardiolipin binding(GO:1901612)
0.1 2.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.9 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.6 GO:0019838 growth factor binding(GO:0019838)
0.0 0.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 4.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.0 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.2 GO:0015293 symporter activity(GO:0015293)
0.0 0.7 GO:0045296 cadherin binding(GO:0045296)
0.0 1.4 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 5.6 GO:0005509 calcium ion binding(GO:0005509)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 0.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 0.7 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 1.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.6 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 3.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.2 0.9 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 3.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 2.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 0.7 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 1.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell