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Results for gli1+gli2b

Z-value: 1.14

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Transcription factors associated with gli1+gli2b

Gene Symbol Gene ID Gene Info
gli2b
ENSDARG00000020884 GLI family zinc finger 2b
gli1
ENSDARG00000101244 GLI family zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gli1dr10_dc_chr6_-_59510397_595104680.924.7e-07Click!

Activity profile of gli1+gli2b motif

Sorted Z-values of gli1+gli2b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of gli1+gli2b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr23_+_20496283 3.83 ENSDART00000144047
ENSDART00000104336
tnnc2
troponin C type 2 (fast)
chr7_+_29680967 3.72 ENSDART00000173540
tpma
alpha-tropomyosin
chr8_+_29953399 3.41 ENSDART00000149372
ENSDART00000007640
ptch1
ptch1
patched 1
patched 1
chr20_-_54206610 3.27 ENSDART00000004756
hsp90aa1.1
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1
chr2_-_34010299 3.09 ENSDART00000140910
ptch2
patched 2
chr18_-_5796081 2.89 ENSDART00000097696
ENSDART00000151453
si:ch1073-459b3.2
si:ch1073-459b3.2
chr23_-_22204223 2.67 ENSDART00000079212
phc2a
polyhomeotic homolog 2a (Drosophila)
chr7_-_26767182 2.67 ENSDART00000052731
nucb2a
nucleobindin 2a
chr10_+_43360137 2.59 ENSDART00000012522
vcanb
versican b
chr5_-_28090077 2.59

chr6_+_6967174 2.48 ENSDART00000151311
ENSDARG00000058903
ENSDARG00000058903
chr10_+_33227967 2.44 ENSDART00000159666
myl10
myosin, light chain 10, regulatory
chr11_-_80746 2.32

chr23_-_27226280 2.30 ENSDART00000141305
si:dkey-157g16.6
si:dkey-157g16.6
chr6_-_22504772 2.27 ENSDART00000170039
sept9b
septin 9b
chr10_-_24422257 2.26 ENSDART00000141332
ENSDART00000100772
slc43a2b
solute carrier family 43 (amino acid system L transporter), member 2b
chr21_-_43020159 2.23 ENSDART00000065097
dpysl3
dihydropyrimidinase-like 3
chr4_+_10722966 2.17 ENSDART00000102534
ENSDART00000067253
ENSDART00000136000
stab2
stabilin 2
chr23_+_34079219 1.94 ENSDART00000132668
si:ch211-207e14.4
si:ch211-207e14.4
chr9_-_23081250 1.92

chr12_-_17357133 1.92 ENSDART00000079115
papss2b
3'-phosphoadenosine 5'-phosphosulfate synthase 2b
chr10_-_14530112 1.81 ENSDART00000176126
galt
galactose-1-phosphate uridylyltransferase
chr8_+_13064944 1.76

chr23_+_28656263 1.75 ENSDART00000020296
nadl1.2
neural adhesion molecule L1.2
chr12_+_27026112 1.72 ENSDART00000076154
hoxb8b
homeobox B8b
chr13_-_39821399 1.70 ENSDART00000056996
sfrp5
secreted frizzled-related protein 5
chr8_-_40287789 1.69 ENSDART00000074125
aplnra
apelin receptor a
chr12_-_457997 1.69 ENSDART00000143232
dhrs7cb
dehydrogenase/reductase (SDR family) member 7Cb
chr21_-_30378764 1.67 ENSDART00000136247
grpel2
GrpE-like 2, mitochondrial
chr23_+_4475256 1.67 ENSDART00000081821
wnt7ab
wingless-type MMTV integration site family, member 7Ab
chr24_-_2278409 1.63

chr15_-_31687 1.61

chr8_+_999710 1.59 ENSDART00000081432
sprb
sepiapterin reductase b
chr23_-_27226387 1.59 ENSDART00000141305
si:dkey-157g16.6
si:dkey-157g16.6
chr22_+_24362712 1.58 ENSDART00000157861
p3h2
prolyl 3-hydroxylase 2
chr24_-_16884946 1.56 ENSDART00000171988
ptgdsb.2
prostaglandin D2 synthase b, tandem duplicate 2
chr15_-_42250788 1.55 ENSDART00000015843
pax3b
paired box 3b
chr20_-_28739099 1.51 ENSDART00000135513
rgs6
regulator of G protein signaling 6
chr12_+_27370834 1.49 ENSDART00000105661
meox1
mesenchyme homeobox 1
chr21_-_91068 1.47

chr14_-_16171165 1.47 ENSDART00000089021
canx
calnexin
chr9_-_10561062 1.47 ENSDART00000175269
thsd7ba
thrombospondin, type I, domain containing 7Ba
chr8_-_4903896 1.47 ENSDART00000004986
igsf9b
immunoglobulin superfamily, member 9b
chr4_+_5124186 1.46 ENSDART00000127874
ccnd2b
cyclin D2, b
chr21_-_37404394 1.46 ENSDART00000129439
BX649250.1
ENSDARG00000091187
chr9_-_46272322 1.43 ENSDART00000169682
hdac4
histone deacetylase 4
chr6_+_9192009 1.43 ENSDART00000022620
kalrnb
kalirin RhoGEF kinase b
chr13_-_9554501 1.41 ENSDART00000139541
ENSDARG00000069828
ENSDARG00000069828
chr3_-_15918262 1.41 ENSDART00000157315
ENSDARG00000097322
ENSDARG00000097322
chr19_-_7069920 1.40 ENSDART00000145741
znf384l
zinc finger protein 384 like
chr6_+_45930323 1.37 ENSDART00000154896
rbp7b
retinol binding protein 7b, cellular
chr23_-_20402258 1.35 ENSDART00000136204
CR749762.2
ENSDARG00000093223
chr15_-_31871 1.25

chr4_+_27141061 1.25 ENSDART00000145083
brd1a
bromodomain containing 1a
chr13_-_40628582 1.18 ENSDART00000111641
ENSDART00000159255
morn4
MORN repeat containing 4
chr2_-_49114158 1.14

chr2_+_47885551 1.11

chr16_+_12740993 1.09 ENSDART00000128497
nat14
N-acetyltransferase 14 (GCN5-related, putative)
chr19_-_12785952 1.03

chr5_+_9542042 1.00 ENSDART00000137543
gstt2
glutathione S-transferase theta 2
chr3_+_47412661 0.96 ENSDART00000155648
ube2ia
ubiquitin-conjugating enzyme E2Ia
chr17_-_33764165 0.95 ENSDART00000043651
dnal1
dynein, axonemal, light chain 1
chr13_-_40628537 0.93 ENSDART00000111641
ENSDART00000159255
morn4
MORN repeat containing 4
chr24_-_6129575 0.89 ENSDART00000021609
gad2
glutamate decarboxylase 2
chr21_+_45693978 0.87 ENSDART00000160324
CABZ01102047.1
ENSDARG00000099648
chr17_-_26586506 0.87 ENSDART00000087062
fam149b1
family with sequence similarity 149, member B1
chr16_-_13704905 0.85 ENSDART00000060004
ntd5
ntl-dependent gene 5
chr15_-_34198725 0.85 ENSDART00000170130
ENSDARG00000101697
ENSDARG00000101697
chr15_-_34198695 0.85 ENSDART00000170130
ENSDARG00000101697
ENSDARG00000101697
chr1_+_30974088 0.84 ENSDART00000144957
as3mt
arsenite methyltransferase
chr1_-_43336274 0.82 ENSDART00000160276
si:ch73-109d9.3
si:ch73-109d9.3
chr7_+_15619409 0.82 ENSDART00000144765
ENSDART00000145946
pax6b
paired box 6b
chr10_+_39211384 0.82

chr21_-_41859818 0.81 ENSDART00000139698
endou2
endonuclease, polyU-specific 2
chr19_-_7069850 0.80 ENSDART00000145741
znf384l
zinc finger protein 384 like
chr21_+_45780315 0.79

chr15_-_47260896 0.78 ENSDART00000098711
eif3k
eukaryotic translation initiation factor 3, subunit K
chr18_+_49230636 0.77 ENSDART00000167609
ENSDART00000135026
ENSDART00000171618
si:ch211-136a13.1
si:ch211-136a13.1
chr13_-_4238224 0.77 ENSDART00000124716
si:dkeyp-121d4.3
si:dkeyp-121d4.3
chr22_+_24362832 0.77 ENSDART00000157861
p3h2
prolyl 3-hydroxylase 2
chr12_-_1545172 0.77

chr23_+_35954132 0.77 ENSDART00000103149
hoxc13a
homeobox C13a
KN150135v1_+_3896 0.75 ENSDART00000174906
CABZ01008508.1
ENSDARG00000106459
chr23_+_200650 0.74

chr7_+_25735562 0.74 ENSDART00000112908
pelp1
proline, glutamate and leucine rich protein 1
chr6_+_7395817 0.74 ENSDART00000150939
ENSDART00000151114
myh10
myosin, heavy chain 10, non-muscle
chr20_-_54645287 0.72 ENSDART00000153389
yy1b
YY1 transcription factor b
chr1_-_30772653 0.71 ENSDART00000087115
rims1b
regulating synaptic membrane exocytosis 1b
chr8_-_386408 0.70

chr5_+_2839985 0.69

chr20_+_26196386 0.64 ENSDART00000139350
syne1a
spectrin repeat containing, nuclear envelope 1a
chr18_-_5796337 0.63

chr11_+_2786083 0.62 ENSDART00000172837
kif21b
kinesin family member 21B
KN150339v1_-_34304 0.60

chr21_-_44707326 0.58 ENSDART00000013814
ammecr1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 homolog (human)
chr3_+_12132746 0.56

chr10_-_39211281 0.54 ENSDART00000148825
slc37a4b
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr5_-_52197945 0.54

chr10_+_17490443 0.52

chr7_+_10460031 0.52 ENSDART00000167323
arnt2
aryl-hydrocarbon receptor nuclear translocator 2
chr10_-_37098396 0.50 ENSDART00000155277
BX323076.2
ENSDARG00000097288
chr16_+_11295005 0.49

chr25_+_32062428 0.49 ENSDART00000152326
sqrdl
sulfide quinone reductase-like (yeast)
chr5_+_35913418 0.47 ENSDART00000013590
wnt11
wingless-type MMTV integration site family, member 11
chr12_-_26323696 0.47

chr20_-_25727347 0.45 ENSDART00000136475
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr22_+_29694605 0.43

chr7_+_20008453 0.42 ENSDART00000012450
dvl2
dishevelled segment polarity protein 2
chr7_+_29680933 0.42 ENSDART00000173540
tpma
alpha-tropomyosin
chr20_-_54206786 0.40 ENSDART00000004756
hsp90aa1.1
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1
chr23_+_4287444 0.39 ENSDART00000012445
zgc:113278
zgc:113278
chr7_+_29681196 0.39 ENSDART00000039657
tpma
alpha-tropomyosin
chr20_+_22780756 0.38

chr21_-_44707514 0.38 ENSDART00000013814
ammecr1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 homolog (human)
chr2_-_59006559 0.38

chr10_-_14530340 0.37 ENSDART00000101298
ENSDART00000138161
galt
galactose-1-phosphate uridylyltransferase
chr20_+_25727285 0.37 ENSDART00000143883
ppat
phosphoribosyl pyrophosphate amidotransferase
chr7_+_29681510 0.36 ENSDART00000173737
tpma
alpha-tropomyosin
chr8_-_16556749 0.35 ENSDART00000101655
calr
calreticulin
chr13_-_4238408 0.33 ENSDART00000124716
si:dkeyp-121d4.3
si:dkeyp-121d4.3
chr18_-_1620953 0.32

chr10_-_45535333 0.31

chr18_+_18598885 0.31

chr7_-_18281871 0.29

chr8_+_7882144 0.29

chr20_+_54645315 0.29

chr21_+_17509116 0.27

chr11_+_40567461 0.26 ENSDART00000160023
errfi1a
ERBB receptor feedback inhibitor 1a
chr9_+_24344001 0.26

chr21_+_42450453 0.26

chr17_-_1496133 0.26 ENSDART00000175509
SLC25A29
solute carrier family 25 member 29
chr18_-_40763343 0.24 ENSDART00000130397
akt2
v-akt murine thymoma viral oncogene homolog 2
chr20_-_51373292 0.22 ENSDART00000027836
ENSDART00000114407
rbm25b
RNA binding motif protein 25b
chr9_+_17855021 0.21 ENSDART00000166566
ENSDART00000060356
dgkh
diacylglycerol kinase, eta
chr5_+_35913494 0.19 ENSDART00000013590
wnt11
wingless-type MMTV integration site family, member 11
chr7_+_25735735 0.19 ENSDART00000112908
pelp1
proline, glutamate and leucine rich protein 1
chr5_+_35839198 0.18 ENSDART00000102973
ENSDART00000103020
eda
ectodysplasin A
chr7_+_10460159 0.16 ENSDART00000158162
arnt2
aryl-hydrocarbon receptor nuclear translocator 2
chr21_-_37404533 0.15 ENSDART00000129439
BX649250.1
ENSDARG00000091187
chr3_+_32711007 0.14 ENSDART00000122228
prr14
proline rich 14
chr7_+_10459899 0.13 ENSDART00000171385
arnt2
aryl-hydrocarbon receptor nuclear translocator 2
chr19_-_42668754 0.13 ENSDART00000132591
si:ch211-191i18.4
si:ch211-191i18.4
chr12_-_31307581 0.12 ENSDART00000153172
vti1a
vesicle transport through interaction with t-SNAREs 1A
chr8_-_43733891 0.10 ENSDART00000166581
ep400
E1A binding protein p400
chr4_+_14659537 0.10

KN149739v1_+_40107 0.07

chr25_+_29631947 0.06 ENSDART00000154849
ENSDARG00000029431
ENSDARG00000029431
chr18_+_58161 0.06

chr14_+_28180174 0.05 ENSDART00000161852
stag2b
stromal antigen 2b
chr2_+_42155813 0.05 ENSDART00000143562
gbp2
guanylate binding protein 2
chr20_+_14073464 0.04 ENSDART00000049864
rd3
retinal degeneration 3
chr23_+_18852697 0.03 ENSDART00000158267
emp3b
epithelial membrane protein 3b
chr11_-_21143897 0.02 ENSDART00000163008
RASSF5
Ras association domain family member 5
chr24_-_39630728 0.01 ENSDART00000031486
lyrm1
LYR motif containing 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.5 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.6 3.7 GO:0045428 regulation of nitric oxide biosynthetic process(GO:0045428) positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
0.6 4.0 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.6 1.7 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
0.5 2.2 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.5 2.2 GO:1901492 regulation of lymphangiogenesis(GO:1901490) positive regulation of lymphangiogenesis(GO:1901492)
0.5 2.8 GO:0032099 regulation of response to food(GO:0032095) negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.4 2.2 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.3 1.9 GO:0050427 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.3 1.6 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.2 0.9 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.2 1.5 GO:0061056 sclerotome development(GO:0061056)
0.2 0.8 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.2 3.8 GO:0014823 response to activity(GO:0014823)
0.2 0.9 GO:1904325 inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of calcium ion transport into cytosol(GO:0010524) positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) regulation of inhibitory G-protein coupled receptor phosphorylation(GO:1904323) positive regulation of inhibitory G-protein coupled receptor phosphorylation(GO:1904325)
0.2 0.8 GO:0090104 pancreatic epsilon cell differentiation(GO:0090104)
0.2 1.6 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 2.3 GO:0044259 collagen metabolic process(GO:0032963) multicellular organismal macromolecule metabolic process(GO:0044259)
0.1 1.3 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 1.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 0.8 GO:0048796 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.1 2.3 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 0.7 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 0.7 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.1 1.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.3 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.8 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.4 GO:0090178 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 1.8 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 4.9 GO:0006936 muscle contraction(GO:0006936)
0.0 1.0 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.7 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.4 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 1.0 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 2.3 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.7 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.3 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.3 3.7 GO:0043209 myelin sheath(GO:0043209)
0.2 3.8 GO:0005861 troponin complex(GO:0005861)
0.1 0.7 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.1 2.7 GO:0035102 PRC1 complex(GO:0035102)
0.1 2.3 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 1.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 2.2 GO:0030426 growth cone(GO:0030426)
0.1 2.7 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 4.9 GO:0005884 actin filament(GO:0005884)
0.0 0.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.8 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 1.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.7 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.7 GO:0016459 myosin complex(GO:0016459)
0.0 2.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.3 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.6 GO:0005871 kinesin complex(GO:0005871)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.5 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.6 2.3 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.5 1.9 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 1.9 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.3 2.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.3 4.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 3.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 2.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.2 0.8 GO:0030792 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.2 0.9 GO:0060182 apelin receptor activity(GO:0060182)
0.1 0.4 GO:0004044 amidophosphoribosyltransferase activity(GO:0004044)
0.1 1.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.4 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.3 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 1.0 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.4 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 2.8 GO:0005109 frizzled binding(GO:0005109)
0.1 2.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 4.9 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 3.5 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.7 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0005123 death receptor binding(GO:0005123)
0.0 1.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.1 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 2.3 GO:0060090 binding, bridging(GO:0060090)
0.0 2.7 GO:0042393 histone binding(GO:0042393)
0.0 0.8 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.9 GO:0008201 heparin binding(GO:0008201)
0.0 1.6 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 0.6 GO:0003777 microtubule motor activity(GO:0003777)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.9 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 2.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.3 2.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 3.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 7.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.9 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import