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Results for glis3

Z-value: 0.88

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Transcription factors associated with glis3

Gene Symbol Gene ID Gene Info
glis3
ENSDARG00000069726 GLIS family zinc finger 3

Activity profile of glis3 motif

Sorted Z-values of glis3 motif

Network of associatons between targets according to the STRING database.

Top targets:

Promoter Score Transcript Gene Gene Info
chr14_-_30363703 3.73 ENSDART00000134098
efemp2a
EGF containing fibulin-like extracellular matrix protein 2a
chr6_-_22504772 3.58 ENSDART00000170039
sept9b
septin 9b
chr15_-_41288480 2.51 ENSDART00000155359
smco4
single-pass membrane protein with coiled-coil domains 4
chr8_-_15144533 2.34 ENSDART00000138855
bcar3
breast cancer anti-estrogen resistance 3
chr8_+_13064944 2.11

chr13_-_508202 2.00 ENSDART00000066080
ENSDART00000128969
slit1a
slit homolog 1a (Drosophila)
chr8_+_46651079 1.87 ENSDART00000113803
her3
hairy-related 3
chr13_-_508050 1.75 ENSDART00000066080
ENSDART00000128969
slit1a
slit homolog 1a (Drosophila)
chr18_+_7350133 1.52 ENSDART00000172404
cers3b
ceramide synthase 3b
chr18_+_9228336 1.13

chr18_-_41384938 0.92 ENSDART00000098673
ptx3a
pentraxin 3, long a
chr14_-_33704021 0.70 ENSDART00000149396
ENSDART00000123607
cyfip2
cytoplasmic FMR1 interacting protein 2
chr5_+_66984082 0.65 ENSDART00000137700
si:dkey-70b23.2
si:dkey-70b23.2
chr13_+_28723589 0.50

chr14_-_28228583 0.46 ENSDART00000054088
zgc:113364
zgc:113364
chr3_+_30059565 0.42 ENSDART00000157320
akt1s1
AKT1 substrate 1 (proline-rich)
chr17_+_23558463 0.38 ENSDART00000149281
slc16a12a
solute carrier family 16, member 12a
chr25_+_7287952 0.26 ENSDART00000170569
syt12
synaptotagmin XII
chr13_-_508110 0.23 ENSDART00000066080
ENSDART00000128969
slit1a
slit homolog 1a (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.3 4.0 GO:0045773 positive regulation of axon extension(GO:0045773)
0.2 2.3 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 0.4 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1 0.7 GO:0001964 startle response(GO:0001964)
0.0 3.6 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.3 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.0 1.5 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 1.9 GO:0045665 negative regulation of neuron differentiation(GO:0045665)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 8.6 GO:0005615 extracellular space(GO:0005615)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.0 GO:0048495 Roundabout binding(GO:0048495)
0.1 1.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.7 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 3.6 GO:0060090 binding, bridging(GO:0060090)
0.0 0.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 2.3 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.3 GO:0001786 phosphatidylserine binding(GO:0001786)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol